Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	EBF2 ZBTB37 ZBTB2 ZBTB38 ZFAT ZSCAN12 PER2 ZFHX4 ZNF544 ZSCAN5A ZSCAN5C ZNF184 ZSCAN26 ZFHX2 ZFHX3 ZNF470 ZNF221 CLOCK ZSCAN23 ZNF646	4.09e-09	1244	69	20	GO:0000978
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	EBF2 ZBTB37 ZBTB2 ZBTB38 ZFAT ZSCAN12 PER2 ZFHX4 ZNF544 ZSCAN5A ZSCAN5C ZNF184 ZSCAN26 ZFHX2 ZFHX3 ZNF470 ZNF221 CLOCK ZSCAN23 ZNF646	5.90e-09	1271	69	20	GO:0000987
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	EBF2 ZBTB37 ZBTB2 ZBTB38 ZFAT ZSCAN12 PER2 ZFHX4 ZNF544 ZSCAN5A ZSCAN5C ZNF184 ZSCAN26 ZFHX2 ZFHX3 ZNF470 ZNF221 ADNP CLOCK ZSCAN23 ZNF646	1.07e-08	1459	69	21	GO:0000977
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	EBF2 ZBTB37 ZBTB2 ZBTB38 ZFAT ZSCAN12 ZFHX4 ZNF544 ZSCAN5A ZSCAN5C ZNF184 ZSCAN26 ZFHX2 ZFHX3 ZNF470 ZNF221 ADNP CLOCK ZSCAN23 ZNF646	3.47e-08	1412	69	20	GO:0000981
MousePheno	arrhythmic circadian behavior persistence	PER2 ZFHX3 CLOCK	3.78e-06	9	51	3	MP:0020472
MousePheno	abnormal circadian behavior persistence	PER2 ZFHX3 CLOCK	7.39e-06	11	51	3	MP:0020471
MousePheno	abnormal circadian behavior phase	PER2 ZFHX3 CLOCK	9.94e-05	25	51	3	MP:0020473
MousePheno	advanced circadian behavior phase	ZFHX3 CLOCK	1.30e-04	5	51	2	MP:0020474
Domain	Znf_C2H2-like	ZNF462 ZBTB37 ZMAT3 RBSN ZBTB2 ZBTB38 ZFAT ZFHX4 ZNF544 ZNF532 ZSCAN5A ZFP64 ZSCAN5C ZNF184 ZSCAN26 CIZ1 ZFHX2 ZFHX3 ZNF470 ZNF221 ADNP ZSCAN23 ZNF646	1.99e-15	796	67	23	IPR015880
Domain	ZnF_C2H2	ZNF462 ZBTB37 ZMAT3 RBSN ZBTB2 ZBTB38 ZFAT ZFHX4 ZNF544 ZNF532 ZSCAN5A ZFP64 ZSCAN5C ZNF184 ZSCAN26 CIZ1 ZFHX2 ZFHX3 ZNF470 ZNF221 ADNP ZSCAN23 ZNF646	2.74e-15	808	67	23	SM00355
Domain	ZINC_FINGER_C2H2_1	ZNF462 ZBTB37 RBSN ZBTB2 ZBTB38 ZFAT ZFHX4 ZNF544 ZNF532 ZSCAN5A ZFP64 ZSCAN5C ZNF184 ZSCAN26 CIZ1 ZFHX2 ZFHX3 ZNF470 ZNF221 ADNP ZSCAN23 ZNF646	1.44e-14	777	67	22	PS00028
Domain	Znf_C2H2	ZNF462 ZBTB37 RBSN ZBTB2 ZBTB38 ZFAT ZFHX4 ZNF544 ZNF532 ZSCAN5A ZFP64 ZSCAN5C ZNF184 ZSCAN26 CIZ1 ZFHX2 ZFHX3 ZNF470 ZNF221 ADNP ZSCAN23 ZNF646	2.96e-14	805	67	22	IPR007087
Domain	ZINC_FINGER_C2H2_2	ZNF462 ZBTB37 RBSN ZBTB2 ZBTB38 ZFAT ZFHX4 ZNF544 ZNF532 ZSCAN5A ZFP64 ZSCAN5C ZNF184 ZSCAN26 ZFHX2 ZFHX3 ZNF470 ZNF221 ADNP ZSCAN23 ZNF646	1.56e-13	775	67	21	PS50157
Domain	Znf_C2H2/integrase_DNA-bd	ZNF462 ZBTB37 ZBTB2 ZBTB38 ZFAT ZFHX4 ZNF544 ZNF532 ZSCAN5A ZFP64 ZSCAN5C ZNF184 ZSCAN26 ZFHX2 ZFHX3 ZNF470 ZNF221 ADNP ZSCAN23 ZNF646	2.16e-13	694	67	20	IPR013087
Domain	zf-C2H2	ZNF462 ZBTB37 ZBTB2 ZBTB38 ZFAT ZFHX4 ZNF544 ZSCAN5A ZFP64 ZSCAN5C ZNF184 ZSCAN26 ZFHX2 ZFHX3 ZNF470 ZNF221 ADNP ZSCAN23 ZNF646	2.35e-12	693	67	19	PF00096
Domain	-	ZNF462 ZBTB37 ZBTB2 ZBTB38 ZFAT ZFHX4 ZNF544 ZNF532 ZSCAN5A ZFP64 ZNF184 ZSCAN26 ZFHX2 ZFHX3 ZNF470 ZNF221 ZSCAN23 ZNF646	1.74e-11	679	67	18	3.30.160.60
Domain	ZnF_U1	ZMAT3 ZFHX4 CIZ1 ZFHX2 ZFHX3	5.67e-08	29	67	5	SM00451
Domain	Znf_U1	ZMAT3 ZFHX4 CIZ1 ZFHX2 ZFHX3	5.67e-08	29	67	5	IPR003604
Domain	SCAN	ZSCAN5A ZSCAN5C ZSCAN26 ZSCAN23	4.83e-05	56	67	4	SM00431
Domain	SCAN_BOX	ZSCAN5A ZSCAN5C ZSCAN26 ZSCAN23	5.55e-05	58	67	4	PS50804
Domain	SCAN	ZSCAN5A ZSCAN5C ZSCAN26 ZSCAN23	5.55e-05	58	67	4	PF02023
Domain	SCAN_dom	ZSCAN5A ZSCAN5C ZSCAN26 ZSCAN23	5.55e-05	58	67	4	IPR003309
Domain	Retrov_capsid_C	ZSCAN5A ZSCAN5C ZSCAN26 ZSCAN23	5.93e-05	59	67	4	IPR008916
Domain	ResIII	IFIH1 FANCM	3.50e-04	8	67	2	PF04851
Domain	Helicase/UvrB_N	IFIH1 FANCM	3.50e-04	8	67	2	IPR006935
Domain	EGF_extracell	ITGBL1 ADAM19 LRP2	1.30e-03	60	67	3	IPR013111
Domain	EGF_2	ITGBL1 ADAM19 LRP2	1.30e-03	60	67	3	PF07974
Domain	ZF_MATRIN	ZMAT3 CIZ1	1.87e-03	18	67	2	PS50171
Domain	EGF-like_dom	ITGBL1 SCUBE1 ADAM19 LRP2 CRB1	1.99e-03	249	67	5	IPR000742
Domain	EGF_1	ITGBL1 SCUBE1 ADAM19 LRP2 CRB1	2.21e-03	255	67	5	PS00022
Domain	EGF_2	ITGBL1 SCUBE1 ADAM19 LRP2 CRB1	2.61e-03	265	67	5	PS01186
Domain	Znf_C2H2_jaz	ZMAT3 CIZ1	2.80e-03	22	67	2	IPR022755
Domain	zf-C2H2_jaz	ZMAT3 CIZ1	2.80e-03	22	67	2	PF12171
Domain	PAS_fold_3	PER2 CLOCK	3.06e-03	23	67	2	IPR013655
Domain	PAS_3	PER2 CLOCK	3.06e-03	23	67	2	PF08447
Domain	cEGF	SCUBE1 LRP2	3.90e-03	26	67	2	IPR026823
Domain	PAC	PER2 CLOCK	3.90e-03	26	67	2	IPR001610
Domain	cEGF	SCUBE1 LRP2	3.90e-03	26	67	2	PF12662
Domain	PAC	PER2 CLOCK	3.90e-03	26	67	2	SM00086
Domain	PAC	PER2 CLOCK	3.90e-03	26	67	2	PS50113
Domain	EGF_Ca-bd_CS	SCUBE1 LRP2 CRB1	5.12e-03	97	67	3	IPR018097
Domain	zf-C2H2_6	ZNF532 ZFP64 ZNF184 ZSCAN23 ZNF646	5.37e-03	314	67	5	PF13912
Domain	EGF_CA	SCUBE1 LRP2 CRB1	5.41e-03	99	67	3	PS01187
Domain	ASX_HYDROXYL	SCUBE1 LRP2 CRB1	5.57e-03	100	67	3	PS00010
Domain	PAS	PER2 CLOCK	5.87e-03	32	67	2	SM00091
Domain	EGF-type_Asp/Asn_hydroxyl_site	SCUBE1 LRP2 CRB1	6.54e-03	106	67	3	IPR000152
Domain	PAS	PER2 CLOCK	6.60e-03	34	67	2	IPR000014
Domain	PAS	PER2 CLOCK	6.60e-03	34	67	2	PS50112
Domain	Helicase_C	IFIH1 CHD6 FANCM	6.71e-03	107	67	3	PF00271
Domain	HELICc	IFIH1 CHD6 FANCM	6.71e-03	107	67	3	SM00490
Domain	Helicase_C	IFIH1 CHD6 FANCM	6.89e-03	108	67	3	IPR001650
Domain	DNA/RNA_helicase_DEAH_CS	CHD6 FANCM	6.99e-03	35	67	2	IPR002464
Domain	HELICASE_CTER	IFIH1 CHD6 FANCM	7.07e-03	109	67	3	PS51194
Domain	HELICASE_ATP_BIND_1	IFIH1 CHD6 FANCM	7.07e-03	109	67	3	PS51192
Domain	DEXDc	IFIH1 CHD6 FANCM	7.07e-03	109	67	3	SM00487
Domain	Helicase_ATP-bd	IFIH1 CHD6 FANCM	7.24e-03	110	67	3	IPR014001
Domain	DEAH_ATP_HELICASE	CHD6 FANCM	8.20e-03	38	67	2	PS00690
Domain	EGF_CA	SCUBE1 LRP2 CRB1	9.61e-03	122	67	3	SM00179
Domain	Homeobox	ZFHX4 ZFHX2 ZFHX3 ADNP	9.94e-03	234	67	4	PF00046
Domain	EGF-like_Ca-bd_dom	SCUBE1 LRP2 CRB1	1.00e-02	124	67	3	IPR001881
Domain	EGF_3	SCUBE1 ADAM19 LRP2 CRB1	1.01e-02	235	67	4	PS50026
Domain	EGF	ITGBL1 SCUBE1 LRP2 CRB1	1.01e-02	235	67	4	SM00181
Domain	HOMEOBOX_1	ZFHX4 ZFHX2 ZFHX3 ADNP	1.02e-02	236	67	4	PS00027
Domain	HOX	ZFHX4 ZFHX2 ZFHX3 ADNP	1.04e-02	237	67	4	SM00389
Domain	HOMEOBOX_2	ZFHX4 ZFHX2 ZFHX3 ADNP	1.07e-02	239	67	4	PS50071
Domain	Homeobox_dom	ZFHX4 ZFHX2 ZFHX3 ADNP	1.07e-02	239	67	4	IPR001356
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	ZNF462 ZBTB37 ZMAT3 ZSCAN12 ZSCAN5A ZFP64 ZSCAN5C CIZ1 PXN ZMYM2 ZFHX3 CLOCK ZNF646	7.32e-09	808	70	13	20412781
Pubmed	Behavioral abnormalities observed in Zfhx2-deficient mice.	ZFHX4 ZFHX2 ZFHX3	3.12e-08	4	70	3	23300874
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	ZNF462 ZFHX4 ZNF532 LRP2 PXN ZMYM2 ZFHX3 CHD6 ADNP	1.63e-07	418	70	9	34709266
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	ZNF462 ZNF184 STEEP1 ZSCAN26 CIZ1 ZMYM2 WDR12 CHD6 ADNP WDR43	3.83e-07	608	70	10	36089195
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	ZSCAN12 PLPPR4 ZNF532 NBEAL2 TMEM131L ADNP CLOCK WDR43 ZNF646	1.16e-06	529	70	9	14621295
Pubmed	NuRD subunit CHD4 regulates super-enhancer accessibility in rhabdomyosarcoma and represents a general tumor dependency.	ZNF462 ZFHX4 ZMYM2 ZFHX3 ADNP	2.15e-06	103	70	5	32744500
Pubmed	Circadian clock-dependent increase in salivary IgA secretion modulated by sympathetic receptor activation in mice.	PER2 CLOCK	3.99e-06	2	70	2	28821839
Pubmed	Circadian regulation of allergic reactions by the mast cell clock in mice.	PER2 CLOCK	3.99e-06	2	70	2	24060274
Pubmed	CLOCKΔ19 mutation modifies the manner of synchrony among oscillation neurons in the suprachiasmatic nucleus.	PER2 CLOCK	3.99e-06	2	70	2	29339832
Pubmed	Clock T3111C and Per2 C111G SNPs do not influence circadian rhythmicity in healthy Italian population.	PER2 CLOCK	3.99e-06	2	70	2	20886252
Pubmed	The circadian mutation PER2(S662G) is linked to cell cycle progression and tumorigenesis.	PER2 CLOCK	3.99e-06	2	70	2	21818120
Pubmed	Local receptors as novel regulators for peripheral clock expression.	PER2 CLOCK	3.99e-06	2	70	2	25145629
Pubmed	A time to fast, a time to feast: the crosstalk between metabolism and the circadian clock.	PER2 CLOCK	3.99e-06	2	70	2	19714310
Pubmed	The mouse ZFH-4 protein contains four homeodomains and twenty-two zinc fingers.	ZFHX4 ZFHX3	3.99e-06	2	70	2	10873665
Pubmed	Feeding cues and injected nutrients induce acute expression of multiple clock genes in the mouse liver.	PER2 CLOCK	3.99e-06	2	70	2	21901130
Pubmed	Paxillin Binding to the Cytoplasmic Domain of CD103 Promotes Cell Adhesion and Effector Functions for CD8+ Resident Memory T Cells in Tumors.	PXN ITGAE	3.99e-06	2	70	2	29021139
Pubmed	Role of intestinal circadian genes in alcohol-induced gut leakiness.	PER2 CLOCK	3.99e-06	2	70	2	21463335
Pubmed	Orexin signaling regulates both the hippocampal clock and the circadian oscillation of Alzheimer's disease-risk genes.	PER2 CLOCK	3.99e-06	2	70	2	27796320
Pubmed	Zfhx3-mediated genetic ablation of the SCN abolishes light entrainable circadian activity while sparing food anticipatory activity.	PER2 ZFHX3	3.99e-06	2	70	2	34632336
Pubmed	Circadian and ultradian rhythms of clock gene expression in the suprachiasmatic nucleus of freely moving mice.	PER2 CLOCK	3.99e-06	2	70	2	26194231
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	ZSCAN5A ZFP64 STEEP1 CIZ1 ZMYM2 CHD6 NKTR ZNF221 FANCM ADNP CLOCK WDR43	9.68e-06	1294	70	12	30804502
Pubmed	Circadian regulation of lipid mobilization in white adipose tissues.	PER2 CLOCK	1.20e-05	3	70	2	23434933
Pubmed	Phosphorylation of DNA-binding domains of CLOCK-BMAL1 complex for PER-dependent inhibition in circadian clock of mammalian cells.	PER2 CLOCK	1.20e-05	3	70	2	38805270
Pubmed	NPAS2 Compensates for Loss of CLOCK in Peripheral Circadian Oscillators.	PER2 CLOCK	1.20e-05	3	70	2	26895328
Pubmed	Expression pattern of circadian genes and steroidogenesis-related genes after testosterone stimulation in the human ovary.	PER2 CLOCK	1.20e-05	3	70	2	27614897
Pubmed	Peripheral circadian oscillators require CLOCK.	PER2 CLOCK	1.20e-05	3	70	2	17637349
Pubmed	For whom the circadian clock ticks? Investigation of PERIOD and CLOCK gene variants in bipolar disorder.	PER2 CLOCK	1.20e-05	3	70	2	34112033
Pubmed	Antisense-Induced Downregulation of Clock Genes in the Shell Region of the Nucleus Accumbens Reduces Binge Drinking in Mice.	PER2 CLOCK	1.20e-05	3	70	2	33606281
Pubmed	Core Circadian Clock Genes Regulate Leukemia Stem Cells in AML.	PER2 CLOCK	1.20e-05	3	70	2	27058663
Pubmed	Disruption of clock gene expression in human colorectal liver metastases.	PER2 CLOCK	1.20e-05	3	70	2	27492458
Pubmed	CLOCK and NPAS2 have overlapping roles in the suprachiasmatic circadian clock.	PER2 CLOCK	1.20e-05	3	70	2	17417633
Pubmed	Characterization and modeling of intermittent locomotor dynamics in clock gene-deficient mice.	PER2 CLOCK	1.20e-05	3	70	2	23516567
Pubmed	The circadian clock protein BMAL1 is necessary for fertility and proper testosterone production in mice.	PER2 CLOCK	1.20e-05	3	70	2	18258755
Pubmed	CLOCK, PER2 and BMAL1 DNA methylation: association with obesity and metabolic syndrome characteristics and monounsaturated fat intake.	PER2 CLOCK	1.20e-05	3	70	2	23003921
Pubmed	Differential Regulation of BMAL1, CLOCK, and Endothelial Signaling in the Aortic Arch and Ligated Common Carotid Artery.	PER2 CLOCK	1.20e-05	3	70	2	27923220
Pubmed	NRF2 regulates core and stabilizing circadian clock loops, coupling redox and timekeeping in Mus musculus.	PER2 CLOCK	1.20e-05	3	70	2	29481323
Pubmed	Photic induction of Period gene expression is reduced in Clock mutant mice.	PER2 CLOCK	1.20e-05	3	70	2	10208599
Pubmed	The Putatively Specific Synthetic REV-ERB Agonist SR9009 Inhibits IgE- and IL-33-Mediated Mast Cell Activation Independently of the Circadian Clock.	PER2 CLOCK	1.20e-05	3	70	2	31847374
Pubmed	Circadian control of the secretory pathway maintains collagen homeostasis.	PER2 CLOCK	1.20e-05	3	70	2	31907414
Pubmed	Regulation of Circadian Clock Genes on Sleep Disorders in Traumatic Brain Injury Patients.	PER2 CLOCK	1.20e-05	3	70	2	31252075
Pubmed	Developmental and reproductive performance in circadian mutant mice.	PER2 CLOCK	1.20e-05	3	70	2	16210390
Pubmed	Two coupled circadian oscillations regulate Bmal1-ELuc and Per2-SLR2 expression in the mouse suprachiasmatic nucleus.	PER2 CLOCK	1.20e-05	3	70	2	30283092
Pubmed	Molecular analysis of avian circadian clock genes.	PER2 CLOCK	1.20e-05	3	70	2	10891604
Pubmed	Human clock, PER1 and PER2 polymorphisms: lack of association with cocaine dependence susceptibility and cocaine-induced paranoia.	PER2 CLOCK	1.20e-05	3	70	2	17106427
Pubmed	PER2 rs2304672, CLOCK rs1801260, and PER3 rs57875989 polymorphisms are not associated with juvenile myoclonic epilepsy.	PER2 CLOCK	1.20e-05	3	70	2	24892753
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	ZNF462 RNF32 RBSN PER2 ZNF532 ZFP64 PXN ZFHX2 ZFHX3	1.24e-05	709	70	9	22988430
Pubmed	Expression and functional analyses of circadian genes in mouse oocytes and preimplantation embryos: Cry1 is involved in the meiotic process independently of circadian clock regulation.	PER2 CLOCK	2.39e-05	4	70	2	19020302
Pubmed	Zscan5b Deficiency Impairs DNA Damage Response and Causes Chromosomal Aberrations during Mitosis.	ZSCAN5A ZSCAN5C	2.39e-05	4	70	2	31155506
Pubmed	Clock-dependent temporal regulation of IL-33/ST2-mediated mast cell response.	PER2 CLOCK	2.39e-05	4	70	2	28259547
Pubmed	Lack of Association between Genetic Polymorphism of Circadian Genes (PER2, PER3, CLOCK and OX2R) with Late Onset Depression and Alzheimer's Disease in a Sample of a Brazilian Population (Circadian Genes, Late-Onset Depression and Alzheimer's Disease).	PER2 CLOCK	2.39e-05	4	70	2	27335043
Pubmed	The BMAL1 C terminus regulates the circadian transcription feedback loop.	PER2 CLOCK	2.39e-05	4	70	2	16777965
Pubmed	Dual modes of CLOCK:BMAL1 inhibition mediated by Cryptochrome and Period proteins in the mammalian circadian clock.	PER2 CLOCK	2.39e-05	4	70	2	25228643
Pubmed	Evidence for clock genes circadian rhythms in human full-term placenta.	PER2 CLOCK	2.39e-05	4	70	2	26247999
Pubmed	Susceptibility rhythm to bacterial endotoxin in myeloid clock-knockout mice.	PER2 CLOCK	2.39e-05	4	70	2	34661529
Pubmed	Expression of clock proteins in developing tooth.	PER2 CLOCK	2.39e-05	4	70	2	21156215
Pubmed	Synchronization of circadian Per2 rhythms and HSF1-BMAL1:CLOCK interaction in mouse fibroblasts after short-term heat shock pulse.	PER2 CLOCK	2.39e-05	4	70	2	21915348
Pubmed	Genetic suppression of the circadian Clock mutation by the melatonin biosynthesis pathway.	PER2 CLOCK	2.39e-05	4	70	2	20404168
Pubmed	Expressions of tight junction proteins Occludin and Claudin-1 are under the circadian control in the mouse large intestine: implications in intestinal permeability and susceptibility to colitis.	PER2 CLOCK	2.39e-05	4	70	2	24845399
Pubmed	Antibodies for assessing circadian clock proteins in the rodent suprachiasmatic nucleus.	PER2 CLOCK	2.39e-05	4	70	2	22558277
Pubmed	Identification of two amino acids in the C-terminal domain of mouse CRY2 essential for PER2 interaction.	PER2 CLOCK	2.39e-05	4	70	2	20840750
Pubmed	Circadian modulation of gene expression, but not glutamate uptake, in mouse and rat cortical astrocytes.	PER2 CLOCK	2.39e-05	4	70	2	19829696
Pubmed	Biochemical analysis of the canonical model for the mammalian circadian clock.	PER2 CLOCK	2.39e-05	4	70	2	21613214
Pubmed	Interactive Organization of the Circadian Core Regulators PER2, BMAL1, CLOCK and PML.	PER2 CLOCK	2.39e-05	4	70	2	27383066
Pubmed	Regulation of clock genes.	PER2 CLOCK	2.39e-05	4	70	2	10487202
Pubmed	The light-dark cycle controls peripheral rhythmicity in mice with a genetically ablated suprachiasmatic nucleus clock.	PER2 CLOCK	2.39e-05	4	70	2	25063847
Pubmed	ZSCAN5B and primate-specific paralogs bind RNA polymerase III genes and extra-TFIIIC (ETC) sites to modulate mitotic progression.	ZSCAN5A ZSCAN5C	2.39e-05	4	70	2	27732952
Pubmed	FTO modulates circadian rhythms and inhibits the CLOCK-BMAL1-induced transcription.	PER2 CLOCK	2.39e-05	4	70	2	26188089
Pubmed	p53 regulates Period2 expression and the circadian clock.	PER2 CLOCK	2.39e-05	4	70	2	24051492
Pubmed	Expression of basic helix-loop-helix/PAS genes in the mouse suprachiasmatic nucleus.	PER2 CLOCK	2.39e-05	4	70	2	10077321
Pubmed	Disruption of the clock components CLOCK and BMAL1 leads to hypoinsulinaemia and diabetes.	PER2 CLOCK	2.39e-05	4	70	2	20562852
Pubmed	Usf1, a suppressor of the circadian Clock mutant, reveals the nature of the DNA-binding of the CLOCK:BMAL1 complex in mice.	PER2 CLOCK	2.39e-05	4	70	2	23580255
Pubmed	PML regulates PER2 nuclear localization and circadian function.	PER2 CLOCK	2.39e-05	4	70	2	22274616
Pubmed	Proteomic analysis of FOXP proteins reveals interactions between cortical transcription factors associated with neurodevelopmental disorders.	ZBTB2 ZFHX4 ZMYM2	2.47e-05	28	70	3	29365100
Pubmed	A novel p53 regulator, C16ORF72/TAPR1, buffers against telomerase inhibition.	ALKBH1 ZBTB38 NALF1 ZFHX4 SHMT1 ADNP WDR43	2.62e-05	431	70	7	33660365
Pubmed	Mammalian circadian autoregulatory loop: a timeless ortholog and mPer1 interact and negatively regulate CLOCK-BMAL1-induced transcription.	PER2 CLOCK	3.98e-05	5	70	2	9856465
Pubmed	SIRT1 regulates circadian clock gene expression through PER2 deacetylation.	PER2 CLOCK	3.98e-05	5	70	2	18662546
Pubmed	Rhythmic CLOCK-BMAL1 binding to multiple E-box motifs drives circadian Dbp transcription and chromatin transitions.	PER2 CLOCK	3.98e-05	5	70	2	16474407
Pubmed	Histone monoubiquitination by Clock-Bmal1 complex marks Per1 and Per2 genes for circadian feedback.	PER2 CLOCK	3.98e-05	5	70	2	26323038
Pubmed	The histone methyltransferase MLL1 permits the oscillation of circadian gene expression.	PER2 CLOCK	3.98e-05	5	70	2	21113167
Pubmed	Circadian Clock Control by Polyamine Levels through a Mechanism that Declines with Age.	PER2 CLOCK	3.98e-05	5	70	2	26456331
Pubmed	Magel2, a Prader-Willi syndrome candidate gene, modulates the activities of circadian rhythm proteins in cultured cells.	PER2 CLOCK	3.98e-05	5	70	2	22208286
Pubmed	Beta-catenin induces beta-TrCP-mediated PER2 degradation altering circadian clock gene expression in intestinal mucosa of ApcMin/+ mice.	PER2 CLOCK	3.98e-05	5	70	2	19106159
Pubmed	Interaction of circadian clock proteins PER2 and CRY with BMAL1 and CLOCK.	PER2 CLOCK	3.98e-05	5	70	2	18430226
Pubmed	BMAL1-dependent circadian oscillation of nuclear CLOCK: posttranslational events induced by dimerization of transcriptional activators of the mammalian clock system.	PER2 CLOCK	3.98e-05	5	70	2	12897057
Pubmed	Gene model 129 (Gm129) encodes a novel transcriptional repressor that modulates circadian gene expression.	PER2 CLOCK	3.98e-05	5	70	2	24385426
Pubmed	CIPC is a mammalian circadian clock protein without invertebrate homologues.	PER2 CLOCK	3.98e-05	5	70	2	17310242
Pubmed	Expression of mCLOCK and other circadian clock-relevant proteins in the mouse suprachiasmatic nuclei.	PER2 CLOCK	3.98e-05	5	70	2	12622829
Pubmed	A molecular mechanism regulating rhythmic output from the suprachiasmatic circadian clock.	PER2 CLOCK	5.96e-05	6	70	2	9989497
Pubmed	Molecular bases for circadian clocks.	PER2 CLOCK	5.96e-05	6	70	2	9988221
Pubmed	cAMP-response element (CRE)-mediated transcription by activating transcription factor-4 (ATF4) is essential for circadian expression of the Period2 gene.	PER2 CLOCK	5.96e-05	6	70	2	21768648
Pubmed	Interacting molecular loops in the mammalian circadian clock.	PER2 CLOCK	5.96e-05	6	70	2	10807566
Pubmed	The role of polymorphisms in circadian pathway genes in breast tumorigenesis.	PER2 CLOCK	5.96e-05	6	70	2	20978934
Pubmed	Poly(ADP-ribose) polymerase 1 participates in the phase entrainment of circadian clocks to feeding.	PER2 CLOCK	5.96e-05	6	70	2	20832105
Pubmed	Molecular assembly of the period-cryptochrome circadian transcriptional repressor complex.	PER2 CLOCK	5.96e-05	6	70	2	25127877
Pubmed	Phosphorylation of clock protein PER1 regulates its circadian degradation in normal human fibroblasts.	PER2 CLOCK	5.96e-05	6	70	2	14750904
Pubmed	Regulation of the PAI-1 promoter by circadian clock components: differential activation by BMAL1 and BMAL2.	PER2 CLOCK	5.96e-05	6	70	2	12738229
Pubmed	Rhythmic PER abundance defines a critical nodal point for negative feedback within the circadian clock mechanism.	PER2 CLOCK	5.96e-05	6	70	2	19917250
Pubmed	Clock genes and body composition in patients with schizophrenia under treatment with antipsychotic drugs.	PER2 CLOCK	5.96e-05	6	70	2	21050724
Pubmed	Preferential inhibition of BMAL2-CLOCK activity by PER2 reemphasizes its negative role and a positive role of BMAL2 in the circadian transcription.	PER2 CLOCK	5.96e-05	6	70	2	19605937
Pubmed	The trophoblast clock controls transport across placenta in mice.	PER2 CLOCK	8.33e-05	7	70	2	33913482
Interaction	H3C3 interactions	ZNF462 ZNF184 STEEP1 ZSCAN26 CIZ1 ZMYM2 WDR12 CHD6 ADNP WDR43	5.16e-06	495	67	10	int:H3C3
Cytoband	19q13.43	ZNF544 ZSCAN5A ZSCAN5C ZNF470	1.00e-05	87	70	4	19q13.43
Cytoband	9q34.1	CIZ1 CRAT	3.85e-04	19	70	2	9q34.1
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF462 ZBTB37 ZBTB2 ZBTB38 ZFAT ZSCAN12 ZNF544 ZNF532 ZSCAN5A ZFP64 ZSCAN5C ZNF184 ZSCAN26 ZFHX2 ZFHX3 ZNF470 ZNF221 ZSCAN23 ZNF646	9.43e-14	718	54	19	28
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZFHX4 ZFHX2 ZFHX3 ADNP	9.47e-08	15	54	4	529
GeneFamily	X-linked mental retardation\|RNA helicases	IFIH1 FANCM	4.73e-04	11	54	2	1168
ToppCell	3'-Broncho-tracheal-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs-Plasmacytoid_DCs_L.1.5.1.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ZAR1L ZFAT ADAM19 NLRP7 AZIN2 GPR183	3.87e-07	179	70	6	c9f45cfea0ceb0cdc31bcfd123aeab69aeb35c35
ToppCell	3'-Distal_airway-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs-Plasmacytoid_DCs_L.1.5.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ZFAT ADAM19 NLRP7 AZIN2 GPR183 TASL	4.00e-07	180	70	6	6a2366d76276452141db1bd93013a9503525f574
ToppCell	LA\|World / Chamber and Cluster_Paper	EBF2 ITGBL1 ADAM19 LRP2 ZFHX3 ABCA10	6.02e-07	193	70	6	d4bf89437216baf489ea0239136dcedf3b6714af
ToppCell	NS-critical-d_07-13-Myeloid-pDC\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	ZFAT ADAM19 NLRP7 GPR183 TASL	6.23e-06	165	70	5	17d5c4a111d9b5400780bc5e7b93ce2f5d69ceb7
ToppCell	10x5'v1-week_12-13-Myeloid_DC-DC-pDC\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	ZFAT ADAM19 NLRP7 AZIN2 GPR183	6.42e-06	166	70	5	9fa90d9d484563d44738bb2c6eb0775dffc4d549
ToppCell	3'-Parenchyma_lung-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs-Plasmacytoid_DCs_L.1.5.1.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ZFAT ADAM19 NLRP7 GPR183 TASL	6.80e-06	168	70	5	59b698f58cb206f0f8f0e8ad72b445d14ba24728
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs-Plasmacytoid_DCs_L.1.5.1.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ZFAT ADAM19 NLRP7 GPR183 TASL	7.20e-06	170	70	5	b49f7c8a27078de2137ed04f74cfee30729cfa5e
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ZFAT ADAM19 NLRP7 GPR183 TASL	7.20e-06	170	70	5	92e765ae0d3adb38d3b22fddb873fd5ccad3fd44
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ZFAT ADAM19 NLRP7 GPR183 TASL	7.20e-06	170	70	5	9f8b215caa1afa3cd7104c06fca7cfd790640f66
ToppCell	BAL-Control-Myeloid-pDC-pDC-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	ZFAT ADAM19 NLRP7 AZIN2 GPR183	8.07e-06	174	70	5	ab654e87c7eab7f33adc61be7a86da5c4d88008d
ToppCell	BAL-Control-Myeloid-pDC\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	ZFAT ADAM19 NLRP7 AZIN2 GPR183	8.07e-06	174	70	5	d9bccff5258c4277bdd1edbd87e17c327ec125e8
ToppCell	BAL-Control-Myeloid-pDC-pDC\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	ZFAT ADAM19 NLRP7 AZIN2 GPR183	8.07e-06	174	70	5	2453419842fd22d066631615403393bfe4449bb8
ToppCell	BAL-Control-Myeloid-pDC\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ZFAT ADAM19 NLRP7 AZIN2 GPR183	8.29e-06	175	70	5	6d5bdfbe53608e01c3845ecd908ca6d0fecc58f8
ToppCell	BAL-Control-Myeloid-pDC-pDC-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ZFAT ADAM19 NLRP7 AZIN2 GPR183	8.29e-06	175	70	5	6839ee3bb4457d13cb08ca8eb79ae33ddd256783
ToppCell	BAL-Control-Myeloid-pDC-pDC\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ZFAT ADAM19 NLRP7 AZIN2 GPR183	8.29e-06	175	70	5	9d6135e183179968555670abec39dff9da2c3219
ToppCell	Control-Myeloid-pDC\|Control / Disease group,lineage and cell class （2021.01.30）	ZFAT ADAM19 NLRP7 AZIN2 GPR183	8.52e-06	176	70	5	baa3563973ea1a351fe028f55828463d2a51bf1a
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	EBF2 ITGBL1 NALF1 PLPPR4 ABCA10	8.76e-06	177	70	5	9ec7f1e64312d26d434b3312b58386715dbad644
ToppCell	3'-Broncho-tracheal-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ZFAT ADAM19 NLRP7 AZIN2 GPR183	8.76e-06	177	70	5	8887ff6341eb070bdaa890cc2cd7745f0cf1b0af
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	EBF2 ITGBL1 NALF1 PLPPR4 ABCA10	8.76e-06	177	70	5	016277dfd59b1793fddaaadc2b3f41622d76ce3a
ToppCell	10x3'2.3-week_12-13-Myeloid_DC-DC-pDC\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	ZFAT ADAM19 NLRP7 AZIN2 GPR183	8.76e-06	177	70	5	e36c2005be74ee8ff03c2052504cb496faf86009
ToppCell	3'-Broncho-tracheal-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ZFAT ADAM19 NLRP7 AZIN2 GPR183	8.76e-06	177	70	5	507f06d31ab773099c9431b6f433899dc97b5566
ToppCell	BAL-Mild-cDC_4\|Mild / Compartment, Disease Groups and Clusters	ZBTB2 ZNF544 AZIN2 LRRK2 FANCM	9.25e-06	179	70	5	68511e87b12b8253de7771e5ccfc5869248b8450
ToppCell	3'-Distal_airway-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ZFAT ADAM19 NLRP7 GPR183 TASL	9.25e-06	179	70	5	4808469096cd6bec2bdfcf4fc55aa324757600c3
ToppCell	3'-Distal_airway-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ZFAT ADAM19 NLRP7 GPR183 TASL	9.25e-06	179	70	5	4d55718c6afd8a038d93cc77b9b08171dab9976f
ToppCell	moderate-Myeloid-pDC\|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	ZFAT ADAM19 NLRP7 GPR183 TASL	9.51e-06	180	70	5	a0751ad5e42a21cb107d900abfa9ee967a0069fc
ToppCell	droplet-Lung-LUNG-30m-Lymphocytic-Ly6g5b+_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZNF462 NALF1 NBEAL2 GPR183 IL23R	9.51e-06	180	70	5	5c649e2b3f5a53c0040b69df6e289fb3427ef2db
ToppCell	NS-moderate-d_16-33-Myeloid-pDC\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	ZFAT ADAM19 NLRP7 GPR183 TASL	9.51e-06	180	70	5	144818e69613296cde43f29cb8c20899c670b319
ToppCell	5'-GW_trimst-2-LymphNode-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	EBF2 ITGBL1 ZFHX4 PLPPR4 ABCA10	1.06e-05	184	70	5	4d4d8f3f44c67d74c57e7af7b7c158f0157b2f49
ToppCell	cellseq-Immune-Immune_Myeloid-Myeloid_Dendritic-pDC\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ZFAT ADAM19 NLRP7 GPR183 TASL	1.11e-05	186	70	5	d23c3318937492d7d665bec14253124c49181b5a
ToppCell	3'-Parenchyma_lung-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs-Plasmacytoid_DCs_L.1.5.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ZFAT ADAM19 NLRP7 GPR183 TASL	1.17e-05	188	70	5	1f820cb19eb0e15f0eb69d07e457072bbdad8ecb
ToppCell	3'-Parenchyma_lung-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ZFAT ADAM19 NLRP7 GPR183 TASL	1.23e-05	190	70	5	c44aae2e0d3cc84a187e12917fd8c2d7483f41d8
ToppCell	3'-Parenchyma_lung-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ZFAT ADAM19 NLRP7 GPR183 TASL	1.23e-05	190	70	5	705489ebbaf3d8e643498c3e507742114475fc55
ToppCell	medial-2-Hematologic-EREG+_Dendritic\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ADAM19 LRRK2 GPR183 PLA2G2C TASL	1.36e-05	194	70	5	b2b4e4c3ac0df0d9f17b930ffb60c0fd85b3dd78
ToppCell	medial-Hematologic-Plasmacytoid_Dendritic\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ZFAT ADAM19 NLRP7 GPR183 TASL	1.36e-05	194	70	5	bb36274d6fe2d18c545a17d3809f331586502d01
ToppCell	medial-Hematologic-EREG+_Dendritic-2\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ADAM19 LRRK2 GPR183 PLA2G2C TASL	1.36e-05	194	70	5	15f3b6b6579e388d0820f05e93a77ee1634bd6c3
ToppCell	medial-Hematologic-EREG+_Dendritic\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ADAM19 LRRK2 GPR183 PLA2G2C TASL	1.36e-05	194	70	5	1f3d22292d2691f93aa7b6770f5c250a33db3cc0
ToppCell	medial-2-Hematologic-Plasmacytoid_Dendritic\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ZFAT ADAM19 NLRP7 GPR183 TASL	1.36e-05	194	70	5	d58be6454a0795d6771036a1620553a153861615
ToppCell	medial-Hematologic-Plasmacytoid_Dendritic-2\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ZFAT ADAM19 NLRP7 GPR183 TASL	1.36e-05	194	70	5	0117cd68750153fd6b8978c8b4ce3589486d2b5f
ToppCell	Biopsy_Control_(H.)-Immune-pDCs\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	ZFAT ADAM19 NLRP7 AZIN2 GPR183	1.40e-05	195	70	5	47d139215f0b51f5ea9b5fb09b1100e320e3f1e2
ToppCell	distal-3-Hematologic-Plasmacytoid_Dendritic\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ZFAT ADAM19 NLRP7 GPR183 TASL	1.43e-05	196	70	5	6028b790abba9bad1d5373bab13eb24855988f48
ToppCell	distal-Hematologic-Plasmacytoid_Dendritic-3\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ZFAT ADAM19 NLRP7 GPR183 TASL	1.47e-05	197	70	5	3a5908deb5c5a2bf06019a102fb1652233cf2a2a
ToppCell	Biopsy_IPF-Immune-pDCs\|Biopsy_IPF / Sample group, Lineage and Cell type	ZFAT ADAM19 NLRP7 AZIN2 GPR183	1.51e-05	198	70	5	aa8943e6796f619406056cf763b751fe9a9a3e0c
ToppCell	distal-Hematologic-Plasmacytoid_Dendritic\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ZFAT ADAM19 NLRP7 GPR183 TASL	1.51e-05	198	70	5	bb03744d8372405c278a0781e2f513bed00cf2b3
ToppCell	BAL-Severe-cDC_1\|Severe / Compartment, Disease Groups and Clusters	IFIH1 ADAM19 GPR183 LY6E TASL	1.54e-05	199	70	5	9f5750212b887f92761ade33fc6e108cd5275297
ToppCell	distal-2-Hematologic-Plasmacytoid_Dendritic\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ZFAT ADAM19 NLRP7 GPR183 TASL	1.54e-05	199	70	5	78796b05d28b35e7361b6271d4a3858faa39c45c
ToppCell	LPS_only-Myeloid-Dendritic_cells-pDC\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ZAR1L ADAM19 GPR183 TASL	6.10e-05	135	70	4	0afe232aa1a1e6c37a5b3183b67d7fa07e0ea791
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PARP4 ZFHX4 LRRK2 CHRM2	7.42e-05	142	70	4	6469cf82552b39f63e20b841c9eed50de6f58d54
ToppCell	LPS-IL1RA-Endothelial-Mes-Like-Gen_Cap\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ITGBL1 ZFHX4 SACS CRB1	8.04e-05	145	70	4	90ca38c02325c5c637c32efdef634b54cc3cd105
ToppCell	LPS_only-Myeloid-Dendritic_cells\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ZAR1L ADAM19 GPR183 TASL	8.71e-05	148	70	4	cb9365663f9cba35d47b5dd9079f42e88b70d915
ToppCell	BAL-Mild-Myeloid-cDC-cDC-cDC_4\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	ZNF544 AZIN2 LRRK2 FANCM	8.94e-05	149	70	4	a85a051e0d82430160967e72fa04b55f43e84513
ToppCell	Leuk-UTI-Lymphocyte-T_NK-dnT\|Leuk-UTI / Disease, Lineage and Cell Type	PTGES2 ZSCAN5A ZNF470 GPR183	8.94e-05	149	70	4	53f145cf7089d948d41aa3c443e983e011826836
ToppCell	TCGA-Bladder-Solid_Tissue_Normal-Urothelial_normal_tissue-Urothelial_normal_tissue-4\|TCGA-Bladder / Sample_Type by Project: Shred V9	SCUBE1 NALF1 PER2 PLPPR4	9.17e-05	150	70	4	bcb99c6fa81052556ab30f9db5875fccf1ae724b
ToppCell	BAL-Mild-Myeloid-cDC-cDC-cDC_4\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ZNF544 AZIN2 LRRK2 FANCM	9.17e-05	150	70	4	7a381f5ae94eba5eb60dcbf83416b4eb18c279ea
ToppCell	356C-Myeloid-Dendritic-pDC\|356C / Donor, Lineage, Cell class and subclass (all cells)	ZFAT ADAM19 NLRP7 TASL	1.07e-04	156	70	4	d9d87368e43b24952e70f31f38425e15b716ff5b
ToppCell	severe-Myeloid-pDC\|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	ZFAT NLRP7 AZIN2 GPR183	1.21e-04	161	70	4	9e8e8ac11f7fb8c8697357c21034b613f191db2b
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L4\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ZAR1L SCUBE1 LRRK2 CHRM2	1.26e-04	163	70	4	1e8ab00ecc2d2ba35aa6745c0ed38663e26312e8
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L4-L4_IT_VISp_Rspo1\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ZAR1L SCUBE1 LRRK2 CHRM2	1.26e-04	163	70	4	431221a41d396b09170476179590eaf8a55266d8
ToppCell	356C-Myeloid-Dendritic-pDC\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	ZFAT ADAM19 ZSCAN12 NLRP7	1.29e-04	164	70	4	fed26f4ac36a2b0722bc7b9f91659c5e0cf4d53a
ToppCell	E18.5-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SACS GPR183 ADNP TASL	1.32e-04	165	70	4	0c80abf13409767825ef8a507b498afafa7e89c5
ToppCell	E18.5-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SACS GPR183 ADNP TASL	1.32e-04	165	70	4	cced77f2d74b07010307d7f4788b8cf3fdaeb91a
ToppCell	severe-Myeloid-pDC\|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	ZFAT NLRP7 AZIN2 GPR183	1.36e-04	166	70	4	ae38850fde549b8dd6fb12f0ef80b428ade50485
ToppCell	Healthy_Control-Lymphoid-pDC\|Healthy_Control / Condition, Lineage, Cell class and cell subclass	ZFAT ADAM19 NLRP7 GPR183	1.45e-04	169	70	4	a4e9b8b2f0338203455ba941b8f99bf4884d26f0
ToppCell	Healthy_Control-Lymphoid-pDC-\|Healthy_Control / Condition, Lineage, Cell class and cell subclass	ZFAT ADAM19 NLRP7 GPR183	1.45e-04	169	70	4	338ce99897cb522b86edd603f75bc15ec4dfcda3
ToppCell	droplet-Lung-nan-18m-Myeloid-Interstitial_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZFAT ADAM19 PLPPR4 ZFHX3	1.52e-04	171	70	4	7ca404539344e14dcd90c746c9122f713a7db78b
ToppCell	3'-Broncho-tracheal-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs-Plasmacytoid_DCs_L.1.5.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ZFAT ADAM19 NLRP7 GPR183	1.52e-04	171	70	4	4fd2c7977c512c51507f055fc74b111c0228ed8b
ToppCell	droplet-Lung-nan-18m-Myeloid-lung_macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZFAT ADAM19 PLPPR4 ZFHX3	1.52e-04	171	70	4	ab113c8e773b0af47a87aed50e96be3ba71c3c82
ToppCell	Pericytes-Donor_02\|World / lung cells shred on cell class, cell subclass, sample id	EBF2 ITGBL1 SCUBE1 CHRM2	1.52e-04	171	70	4	bbc8d9fc83d37c9250345b1e76776610799de9ae
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-Plasmacytoid_Dendritic_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ZFAT ADAM19 GPR183 TASL	1.52e-04	171	70	4	39c8ae139e449217091e1481eb5e2aafb8f69a1c
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-Plasmacytoid_Dendritic_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ZFAT ADAM19 GPR183 TASL	1.52e-04	171	70	4	af1c93eb75f45c042ea475d93db56e4da207e31f
ToppCell	5'-GW_trimst-2-SmallIntestine-Hematopoietic-Myeloid-pDC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ZFAT NLRP7 GPR183 TASL	1.55e-04	172	70	4	b84610f1e5889a655652800c2b3270d264bfe1a9
ToppCell	Epithelial-Epithelial-C_(AT2)\|Epithelial / shred on cell class and cell subclass (v4)	ADAM19 LRRK2 LRP2 LY6E	1.59e-04	173	70	4	f57cbf5bd2a9e5db47b4919e9cd5e50781c1a990
ToppCell	3'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid-pDC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ZFAT NLRP7 GPR183 TASL	1.62e-04	174	70	4	4120656e6d6cf5435a248326b5fdbdc7b22137af
ToppCell	343B-Lymphocytic-NK_cells-NK_cell_E\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	SCUBE1 ZNF184 SIK2 TASL	1.66e-04	175	70	4	78a86cac3e6c0d115c997d1c29ee0e24af54551f
ToppCell	facs-Marrow-B-cells-24m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZFHX4 LRP2 GPR183 LY6E	1.66e-04	175	70	4	887e75fc90e59a6394d62f3c048a9cfdf6707725
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c04-ANXA2\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	PTGES2 ADAM19 GPR183 LY6E	1.66e-04	175	70	4	5f5fc1bf29f07e086951d4f9486b5f07bdcc5d4f
ToppCell	mild-Myeloid-pDC\|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	ZFAT NLRP7 AZIN2 GPR183	1.70e-04	176	70	4	59a9c262c252b7d220a025837922d98e9d6b0a24
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RNF32 SACS LRRK2 CRB1	1.70e-04	176	70	4	33323c97afe509147956b8df9f92ca6b0537e604
ToppCell	CV-Severe-7\|Severe / Virus stimulation, Condition and Cluster	PIGN ADAM19 SIK2 IL23R	1.73e-04	177	70	4	82fdd6185b368f54f03de389427cbe3071d21a99
ToppCell	myeloid-Dendritic_cell-Plasmacytoid_dendritic_cell\|myeloid / Lineage, cell class and subclass	ZFAT NLRP7 AZIN2 CRB1	1.77e-04	178	70	4	f75591988bbbeba073b66329a3437cb9b02f7648
ToppCell	390C-Lymphocytic-ILC-ILC-1\|390C / Donor, Lineage, Cell class and subclass (all cells)	ZFAT ZSCAN26 SIK2 TMEM131L	1.81e-04	179	70	4	e7045e27f0eb88f552b31c04b56d78e5ccd7a36c
ToppCell	LA-01._Fibroblast_I\|LA / Chamber and Cluster_Paper	EBF2 ITGBL1 ZFHX3 ABCA10	1.81e-04	179	70	4	dcb6ec9ae72b13fe388b72dace2815293fafe8ee
ToppCell	moderate-Myeloid-pDC\|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	ZFAT ADAM19 NLRP7 GPR183	1.85e-04	180	70	4	1d8df7df03a71f49d6683554d3c948ce90dda42e
ToppCell	3'_v3-Lung-Myeloid_Dendritic-pDC\|Lung / Manually curated celltypes from each tissue	ZFAT ADAM19 NLRP7 GPR183	1.89e-04	181	70	4	3d7f089fb434fbc989f1fa159e22133ae00b2487
ToppCell	wk_20-22-Hematologic-Myeloid-pDC\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	ZFAT ADAM19 NLRP7 GPR183	1.89e-04	181	70	4	60607c5ff6d5b1cb416adc034491dca31c41e988
ToppCell	B_cells-ISG-high_B_cells\|World / Immune cells in Kidney/Urine in Lupus Nephritis	TDRD7 IFIH1 ADAM19 TASL	1.97e-04	183	70	4	dc2b00e920efa1dcc2a6265cd1024e3249c9974f
ToppCell	BAL-Control-Myeloid-cDC-cDC-cDC_1\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	IFIH1 ADAM19 GPR183 TASL	1.97e-04	183	70	4	bd78e5c2670e67b4363078e3ca5a5b7081d24b7e
ToppCell	BAL-Control-Myeloid-cDC-cDC-cDC_1\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	IFIH1 ADAM19 GPR183 TASL	1.97e-04	183	70	4	d1bf3abf42eb9d7facf775becf1338d1faadd647
ToppCell	droplet-Lung-nan-21m-Lymphocytic-Ly6g5b+_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZNF462 GPR183 ITGAE IL23R	1.97e-04	183	70	4	302bd0f1f8025f385a764f2a9adafdd7f1f67ea3
ToppCell	droplet-Lung-30m-Hematologic-lymphocytic-immature_innate_lymphoid_cell\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ZNF462 NALF1 GPR183 IL23R	2.01e-04	184	70	4	3d8008f8d2e39c0d7a3cabc45620027491da03cf
ToppCell	URO-Myeloid-pDC\|URO / Disease, Lineage and Cell Type	ZFAT NLRP7 GPR183 TASL	2.01e-04	184	70	4	0edb5dd003c2bca0b9e3ec18d03610d68bd52538
ToppCell	droplet-Lung-30m-Hematologic-lymphocytic-immature_innate_lymphoid_cell-Ly6g5b+_T\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ZNF462 NALF1 GPR183 IL23R	2.01e-04	184	70	4	eeed75984ff111c0d1750df2f978163a42f20207
ToppCell	PBMC-Mild-cDC_9\|Mild / Compartment, Disease Groups and Clusters	PIGN IFIH1 SCUBE1 ADAM19	2.01e-04	184	70	4	2e0c9a2c40c892a2d435eafb31f1f838de9baf15
ToppCell	Leuk-UTI-Other-RBC\|Leuk-UTI / Disease, Lineage and Cell Type	ZFAT NLRP7 AZIN2 GPR183	2.05e-04	185	70	4	5b5dd856d6efc0539d92533cff134bbc3f98be45
ToppCell	Leuk-UTI-Other\|Leuk-UTI / Disease, Lineage and Cell Type	ZFAT NLRP7 AZIN2 GPR183	2.05e-04	185	70	4	895e8087e97ac0eab3446385e6e0dd24bea7f42c
ToppCell	ICU-NoSEP-Myeloid-pDC\|ICU-NoSEP / Disease, Lineage and Cell Type	ZFAT NLRP7 AZIN2 GPR183	2.05e-04	185	70	4	7564a47df4a4e3af30d40aa0f48bd9d9c82358ae
ToppCell	COVID-19_Convalescent-PLT_4\|World / Disease Group and Platelet Clusters	PTGES2 RBSN ZMYM2 GPR183	2.10e-04	186	70	4	5954a1e3ffafb33f2a9bc87af3343f304fda4c92
ToppCell	5'-Airway_Nasal-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ZFAT ADAM19 NLRP7 GPR183	2.10e-04	186	70	4	0096a61b1841784c913752b4f3639200446cc02c
ToppCell	5'-Airway_Nasal-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs-Plasmacytoid_DCs_L.1.5.1.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ZFAT ADAM19 NLRP7 GPR183	2.10e-04	186	70	4	6345777847960c71a2ba3ce5a49c72c34ebd0e73
ToppCell	control-Myeloid-pDC\|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	ZFAT NLRP7 AZIN2 GPR183	2.10e-04	186	70	4	fccee4cfcc887358cf916d974f29627095b5ad9c
ToppCell	5'-Airway_Nasal-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ZFAT ADAM19 NLRP7 GPR183	2.10e-04	186	70	4	9e159ad7289dcae2ec7ce655df746f46801b81d3
Disease	anxiety, stress-related disorder, major depressive disorder	ZSCAN12 ZNF184 ZSCAN26 ZSCAN23	3.69e-06	46	67	4	EFO_0005230, EFO_0010098, MONDO_0002009
Disease	Influenza	TDRD7 IFIH1 LY6E	2.28e-04	52	67	3	C0021400
Disease	autoimmune thyroiditis (is_implicated_in)	ZFAT LRP2	3.30e-04	12	67	2	DOID:7188 (is_implicated_in)
Disease	anorexia nervosa	NALF1 LRP2 CRB1	5.49e-04	70	67	3	MONDO_0005351
Disease	autoimmune thyroid disease, systemic lupus erythematosus, type 1 diabetes mellitus, ankylosing spondylitis, psoriasis, common variable immunodeficiency, celiac disease, ulcerative colitis, Crohn's disease, autoimmune disease, juvenile idiopathic arthritis	LRRK2 IL23R CRB1	5.49e-04	70	67	3	EFO_0000384, EFO_0000676, EFO_0000729, EFO_0001060, EFO_0002609, EFO_0003898, EFO_0005140, EFO_0006812, MONDO_0005147, MONDO_0007915, MONDO_0015517
Disease	Crohn's disease (is_implicated_in)	LRRK2 IL23R	2.12e-03	30	67	2	DOID:8778 (is_implicated_in)

Protein segments in the cluster

Peptide	Gene	Start	Entry
LLNCPYCTFNADKKT	ADNP	106	Q9H2P0
FSVACNTKKLNCFPV	ABCA10	881	Q8WWZ4
KQCLKLYSQKPNVCN	ALKBH1	116	Q13686
YYCCRQNNKLGQLKP	ADAM19	721	Q9H013
CANPCKQIAQIKYAA	AZIN2	111	Q96A70
FLKFFLKCNQNCLKT	EBF2	186	Q9HAK2
KPLCMNQYYQILSSC	CRAT	166	P43155
NPACYALCNATFKKT	CHRM2	436	P08172
CPLCLKDLQSFYQLH	RBSN	16	Q9H1K0
KLKEFSCQPVLNSYQ	PLA2G2C	71	Q5R387
LNSLKCINYPSEKSC	FANCM	1051	Q8IYD8
QLPYEKACKNKLFCV	ITGAE	816	P38570
LACKNQPTCSYQQIS	PER2	571	O15055
KCPTLKQFNLSYNQL	LRRK2	1081	Q5S007
YNKSVPNLCKQICSH	LRP2	4326	P98164
FANCIFCLKVKYLPQ	PARP4	6	Q9UKK3
QNDKPYCQNCFLKLF	PXN	576	P49023
PGNLCCLYQTNSKLY	CHD6	1626	Q8TD26
YCQAAIKNCQPRKLH	IL23R	51	Q5VWK5
YKNNPSLITFLCKNC	IFIH1	896	Q9BYX4
CLNQKSNLYCLKPTI	LY6E	26	Q16553
YIKNSFCNKNNTRCL	CRB1	21	P82279
YLTCNPQLGKRKFCS	CT62	66	P0C5K7
IDAICQNTPKSYKCL	SCUBE1	46	Q8IWY4
ISNYCKKTPSNNITC	SACS	356	Q9NZJ4
CQYPTNCDLTKKKSN	ITGBL1	126	O95965
NFYCDVPQLIKLACT	OR4D5	176	Q8NGN0
CQKRALQAYKLDPQC	SHMT1	96	P34896
KKCAKCGLPLFYQSQ	STEEP1	91	Q9H5V9
SLHNKVCQQLKGCYL	TMEM131L	236	A2VDJ0
QLFSDICPKTCKNFL	NKTR	26	P30414
KNTLCNYDPSKTCYQ	NXPH1	206	P58417
LLHYSPQACKNNICL	NBEAL2	846	Q6ZNJ1
YSQICCKLFRTAKQN	GPR183	216	P32249
NKKTCPLCRKNQYQT	RNF32	161	Q9H0A6
KPSLLSKAQNTCQLY	SIK2	686	Q9H0K1
SYPDCKLQTLVLQQC	NLRP7	871	Q8WX94
QLTLYQYKTCPFCSK	PTGES2	101	Q9H7Z7
TLYCQVPCKGLNKLS	TDRD7	666	Q8NHU6
TPEYLKSKNQLEFCC	CLOCK	181	O15516
PSKQALQFFCYICKA	CIZ1	586	Q9ULV3
CKPNYTSLNVSCKEN	PLPPR4	211	Q7Z2D5
FKCPDCSLLYAQKQL	ZNF532	936	Q9HCE3
IYQCKLCNYNTQLKA	ZFHX4	916	Q86UP3
SNTDNKPYKCSICNV	ZFHX4	1541	Q86UP3
CPQCSYASAIKANLN	ZFAT	301	Q9P243
PRLTCIYCAKSFNQK	ZBTB37	371	Q5TC79
KLCCYGTQLKANFQL	ZFHX2	761	Q9C0A1
YLVPSSCKSICKNYN	TASL	111	Q9HAI6
PYTCDVCQKQFTQKS	ZSCAN5A	411	Q9BUG6
YPCSLCSKQLFNAAA	ZNF646	401	O15015
PYQCKQCNKAFSQLA	ZNF470	311	Q6ECI4
VCCKQKLTSIQFSYN	PIGN	756	O95427
APSDIQLKCNYCKNS	ZMYM2	631	Q9UBW7
QLKCNYCKNSFCSKP	ZMYM2	636	Q9UBW7
PFKCNICQKAFRLNS	ZSCAN26	421	Q16670
QQKPYRCNECKQSFS	ZNF221	166	Q9UK13
PYKCNQCNKAFARSS	ZNF544	631	Q6NX49
LFKCALCAYTNPIRK	ZNF462	1696	Q96JM2
LCKPLYCKLCNVTLN	ZMAT3	66	Q9HA38
LVQTNKPYKCNLCDK	ZBTB2	441	Q8N680
LVCKYCNKQFTTLNR	ZBTB38	371	Q8NAP3
GNKVFNCISYSPLCK	WDR12	296	Q9GZL7
TRDKPYQCTQCNKSF	ZSCAN12	381	O43309
FKCQICPYASRNSSQ	ZFP64	231	Q9NTW7
PYTCDICQKQFTQKS	ZSCAN5C	411	A6NGD5
YFKQLCCKCQKSFNP	ZAR1L	251	A6NP61
KPYNCNECRKTFSQS	ZNF184	696	Q99676
YCKKPLTSNCTIQIA	WDR43	306	Q15061
CKLCRYNTQLKANFQ	ZFHX3	986	Q15911
KPYQCNQCNKSFSRR	ZSCAN23	331	Q3MJ62
QFNCRKTIPCKQYCL	NALF1	321	B1AL88