Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	very long-chain fatty acid-CoA ligase activity	SLC27A1 SLC27A5 SLC27A3	5.50e-05	10	157	3	GO:0031957
GeneOntologyMolecularFunction	intracellular sodium-activated potassium channel activity	KCNT2 KCNT1	6.14e-05	2	157	2	GO:0005228
GeneOntologyMolecularFunction	long-chain fatty acid-CoA ligase activity	SLC27A1 SLC27A5 SLC27A3	2.02e-04	15	157	3	GO:0004467
GeneOntologyMolecularFunction	RNA polymerase I core binding	RRN3P2 RRN3	3.65e-04	4	157	2	GO:0001042
GeneOntologyCellularComponent	chromatin	SOX2 FOXN1 TBX3 NR2F6 CDX1 DEAF1 FOXO6 KLF14 ZNF385A RUNX2 PELP1 GLYR1 DMRTB1 ACTL6B NKX6-1 BRD1 TAL1 PLK3 DDX11L8 SLX4 NR1I3 DNMT1 FOXL1 NPAS2 TBX6	1.24e-04	1480	158	25	GO:0000785
Domain	EGF_LAM_2	HSPG2 STAB1 CELSR1 CELSR3	9.80e-05	30	152	4	PS50027
Domain	EGF_LAM_1	HSPG2 STAB1 CELSR1 CELSR3	9.80e-05	30	152	4	PS01248
Domain	IGc2	SEMA3F HSPG2 SPEG FSTL4 IGDCC3 CILP2 ROBO2 ALPK2 LILRA4	1.34e-04	235	152	9	SM00408
Domain	Ig_sub2	SEMA3F HSPG2 SPEG FSTL4 IGDCC3 CILP2 ROBO2 ALPK2 LILRA4	1.34e-04	235	152	9	IPR003598
Domain	EGF_Lam	HSPG2 STAB1 CELSR1 CELSR3	1.81e-04	35	152	4	SM00180
Domain	Laminin_EGF	HSPG2 STAB1 CELSR1 CELSR3	1.81e-04	35	152	4	PF00053
Domain	Laminin_EGF	HSPG2 STAB1 CELSR1 CELSR3	2.51e-04	38	152	4	IPR002049
Domain	AMP-bd_C	SLC27A1 SLC27A5 SLC27A3	3.30e-04	17	152	3	IPR025110
Domain	AMP-binding_C	SLC27A1 SLC27A5 SLC27A3	3.30e-04	17	152	3	PF13193
Domain	BK_channel_a	KCNT2 KCNT1	3.91e-04	4	152	2	PF03493
Domain	K_chnl_Ca-activ_BK_asu	KCNT2 KCNT1	3.91e-04	4	152	2	IPR003929
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	SEMA3F HSPG2 NR2F6 SPEG HUWE1 EDC4 ARHGEF11 NPHP4 RASSF7 NR2F2 SBNO2 SLC52A3 CELSR1 MROH1 CELSR3 SCN5A HELZ2 IRS2 SIPA1L2 TTC5 MMP17 PLK3 MED13	1.27e-09	1105	158	23	35748872
Pubmed	Dissecting Wnt/beta-catenin signaling during gastrulation using RNA interference in mouse embryos.	SOX2 CDX1 IGDCC3 XDH TBX6	8.96e-08	25	158	5	15857914
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	NR2F6 DEAF1 COPA TCOF1 SEPTIN9 IQCN HUWE1 HEXIM2 TUBGCP6 ZNF106 GSE1 HELZ2 IRS2 EXOC2 PARD3 MED13 DNMT1	1.00e-07	774	158	17	15302935
Pubmed	A family of fatty acid transporters conserved from mycobacterium to man.	SLC27A1 SLC27A5 SLC27A3	1.82e-06	6	158	3	9671728
Pubmed	Dystroglycan is a scaffold for extracellular axon guidance decisions.	CELSR1 CELSR3 ROBO2	1.82e-06	6	158	3	30758284
Pubmed	Differential expression of fatty acid transport proteins in epidermis and skin appendages.	SLC27A1 SLC27A5 SLC27A3	3.18e-06	7	158	3	16354187
Pubmed	Advances in the understanding of skeletal muscle weakness in murine models of diseases affecting nerve-evoked muscle activity, motor neurons, synapses and myofibers.	HSPG2 ACHE BCL3	3.18e-06	7	158	3	25042397
Pubmed	A census of human transcription factors: function, expression and evolution.	SOX2 FOXN1 TBX3 NR2F6 CDX1 DEAF1 ZNF385A RUNX2 NR2F2 DMRTB1 NKX6-1 TAL1 NR1I3 FOXL1 NPAS2 TBX6	4.25e-06	908	158	16	19274049
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	NRDE2 MED16 PPFIA1 PRDX4 RBM42 ZNF385A EDC4 AP3B1 ARHGEF11 MFF DNTTIP1 KIAA1671 RMDN3 CELSR1 FAM120C HELZ2 MCAT EXOC2 PARD3 MED13 NR1I3	4.61e-06	1497	158	21	31527615
Pubmed	X-linked adrenoleukodystrophy: role of very long-chain acyl-CoA synthetases.	SLC27A1 SLC27A5 SLC27A3	5.07e-06	8	158	3	15464426
Pubmed	Deficiency of Wdr60 and Wdr34 cause distinct neural tube malformation phenotypes in early embryos.	DYNC2I2 CELSR1 CELSR3 NKX6-1	5.67e-06	26	158	4	37228654
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	FOXN1 NR2F6 FOXO6 COPA HUWE1 PRPF8 NR2F2 HEXIM2 DNTTIP1 RMDN3 GSE1 PELP1 GLYR1 NKX6-1 FOXL1	9.32e-06	857	158	15	25609649
Pubmed	Trait-associated noncoding variant regions affect TBX3 regulation and cardiac conduction.	TBX3 RYR2 SCN5A	1.08e-05	10	158	3	32672536
Pubmed	Crumbs2 mediates ventricular layer remodelling to form the spinal cord central canal.	SOX2 NKX6-1 PARD3	1.08e-05	10	158	3	32150534
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	TCOF1 WDR7 PPFIA1 GPRIN3 HUWE1 AP3B1 MFF RYR2 TASOR2 KIAA1671 CD5 RELL1 PARD3 DNMT1	1.36e-05	777	158	14	35844135
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	SEPTIN9 IQCN ZNF385A HUWE1 ATP10A NEK9 HEXIM2 SBNO2 TASOR2 DNTTIP1 KIAA1671 DNAAF5 FAM120C GLYR1 EEPD1 NUP210 MAST1 PRKAG2 PARD3 NPAS2	1.49e-05	1489	158	20	28611215
Pubmed	The expression and function of fatty acid transport protein-2 and -4 in the murine placenta.	SLC27A1 SLC27A5 SLC27A3	1.96e-05	12	158	3	22028793
Pubmed	Genome-wide detection of allele specific copy number variation associated with insulin resistance in African Americans from the HyperGEN study.	AP3B1 ATP10A SEZ6L	1.96e-05	12	158	3	21901158
Pubmed	Cell volume changes regulate slick (Slo2.1), but not slack (Slo2.2) K+ channels.	KCNT2 KCNT1	2.05e-05	2	158	2	25347289
Pubmed	Rrn3 phosphorylation is a regulatory checkpoint for ribosome biogenesis.	RRN3P2 RRN3	2.05e-05	2	158	2	12015311
Pubmed	NPAS2 as a transcriptional regulator of non-rapid eye movement sleep: genotype and sex interactions.	SCN5A NPAS2	2.05e-05	2	158	2	16636276
Pubmed	Loss of Nav1.5 expression and function in murine atria containing the RyR2-P2328S gain-of-function mutation.	RYR2 SCN5A	2.05e-05	2	158	2	23723061
Pubmed	Reduced activity and cytoplasmic localization of Runx2 is observed in C3h10t1/2 cells overexpressing Tbx3.	TBX3 RUNX2	2.05e-05	2	158	2	21455926
Pubmed	Positional cloning of a gene involved in the pathogenesis of Treacher Collins syndrome. The Treacher Collins Syndrome Collaborative Group.	CDX1 TCOF1	2.05e-05	2	158	2	8563749
Pubmed	Evidence for RPGRIP1 gene as risk factor for primary open angle glaucoma.	RPGRIP1 NPHP4	2.05e-05	2	158	2	21224891
Pubmed	PELP1 promotes the expression of RUNX2 via the ERK pathway during the osteogenic differentiation of human periodontal ligament stem cells.	RUNX2 PELP1	2.05e-05	2	158	2	33607589
Pubmed	A neuroprotective phase precedes striatal degeneration upon nucleolar stress.	RRN3P2 RRN3	2.05e-05	2	158	2	23764776
Pubmed	Slack and Slick K(Na) channels regulate the accuracy of timing of auditory neurons.	KCNT2 KCNT1	2.05e-05	2	158	2	17344399
Pubmed	Non-motor symptoms associated with progressive loss of dopaminergic neurons in a mouse model of Parkinson's disease.	RRN3P2 RRN3	2.05e-05	2	158	2	38745938
Pubmed	Function of the growth-regulated transcription initiation factor TIF-IA in initiation complex formation at the murine ribosomal gene promoter.	RRN3P2 RRN3	2.05e-05	2	158	2	8413268
Pubmed	Evidence of a dosage effect and a physiological endplate acetylcholinesterase deficiency in the first mouse models mimicking Schwartz-Jampel syndrome neuromyotonia.	HSPG2 ACHE	2.05e-05	2	158	2	18647752
Pubmed	Loss of SPEG Inhibitory Phosphorylation of Ryanodine Receptor Type-2 Promotes Atrial Fibrillation.	SPEG RYR2	2.05e-05	2	158	2	32683896
Pubmed	Stimulation of noradrenergic transmission by reboxetine is beneficial for a mouse model of progressive parkinsonism.	RRN3P2 RRN3	2.05e-05	2	158	2	30918302
Pubmed	Heat shock represses rRNA synthesis by inactivation of TIF-IA and lncRNA-dependent changes in nucleosome positioning.	RRN3P2 RRN3	2.05e-05	2	158	2	27257073
Pubmed	Cardiac Slo2.1 Is Required for Volatile Anesthetic Stimulation of K+ Transport and Anesthetic Preconditioning.	KCNT2 KCNT1	2.05e-05	2	158	2	26845140
Pubmed	ERK-dependent phosphorylation of the transcription initiation factor TIF-IA is required for RNA polymerase I transcription and cell growth.	RRN3P2 RRN3	2.05e-05	2	158	2	12620228
Pubmed	Purkinje Cells as Sources of Arrhythmias in Long QT Syndrome Type 3.	RYR2 SCN5A	2.05e-05	2	158	2	26289036
Pubmed	Molecular mechanisms of Slo2 K+ channel closure.	KCNT2 KCNT1	2.05e-05	2	158	2	27682982
Pubmed	Genetic analysis in post-mortem samples with micro-ischemic alterations.	RYR2 SCN5A	2.05e-05	2	158	2	28086167
Pubmed	Integration of the Deacetylase SIRT1 in the Response to Nucleolar Stress: Metabolic Implications for Neurodegenerative Diseases.	RRN3P2 RRN3	2.05e-05	2	158	2	31110473
Pubmed	DNA binding by the ribosomal DNA transcription factor rrn3 is essential for ribosomal DNA transcription.	RRN3P2 RRN3	2.05e-05	2	158	2	23393135
Pubmed	Differential distribution of the sodium-activated potassium channels slick and slack in mouse brain.	KCNT2 KCNT1	2.05e-05	2	158	2	26587966
Pubmed	Impaired rRNA synthesis triggers homeostatic responses in hippocampal neurons.	RRN3P2 RRN3	2.05e-05	2	158	2	24273493
Pubmed	Sodium-activated potassium channels shape peripheral auditory function and activity of the primary auditory neurons in mice.	KCNT2 KCNT1	2.05e-05	2	158	2	30796290
Pubmed	Interaction of nephrocystin-4 and RPGRIP1 is disrupted by nephronophthisis or Leber congenital amaurosis-associated mutations.	RPGRIP1 NPHP4	2.05e-05	2	158	2	16339905
Pubmed	Temporal requirements for ISL1 in sympathetic neuron proliferation, differentiation, and diversification.	TBX3 RYR2 CELSR3 GSE1 DNMT1	2.76e-05	77	158	5	29445148
Pubmed	Ligand-activated peroxisome proliferator activated receptor gamma alters placental morphology and placental fatty acid uptake in mice.	SLC27A1 SLC27A5 SLC27A3	3.23e-05	14	158	3	17463056
Pubmed	FoxO6 regulates Hippo signaling and growth of the craniofacial complex.	SOX2 FOXO6 RUNX2	3.23e-05	14	158	3	30286078
Pubmed	A non-autonomous function of the core PCP protein VANGL2 directs peripheral axon turning in the developing cochlea.	SOX2 CELSR1 CELSR3	3.23e-05	14	158	3	29784671
Pubmed	Interaction of Sox2 with RNA binding proteins in mouse embryonic stem cells.	SOX2 TBX3 PRPF8 DNTTIP1 GLYR1 PRKAG2	3.70e-05	135	158	6	31077711
Pubmed	Proteomic identification of brain proteins that interact with dynein light chain LC8.	MTR MAST1 PARD3 DNMT1	4.01e-05	42	158	4	14760703
Pubmed	Role of Rb during Neurogenesis and Axonal Guidance in the Developing Olfactory System.	SOX2 SEMA3F ROBO2	4.02e-05	15	158	3	27667971
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	PPFIA1 RALGPS2 EDC4 ARHGEF17 NEK9 RASSF7 KIAA1671 ZNF106 GAN IRS2 BRD1 PARD3 SIPA1L2 DNMT1	4.18e-05	861	158	14	36931259
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	COPA TCOF1 PRDX4 HUWE1 EDC4 PRPF8 TASOR2 PELP1 GLYR1 NUP210 HELZ2 DNMT1	4.74e-05	653	158	12	22586326
Pubmed	Assessment of a polymorphism of SDK1 with hypertension in Japanese Individuals.	SEMA3F SEPTIN9 ATP10A SPTBN5 CELSR1 NUP210	4.92e-05	142	158	6	19851296
Pubmed	Hindgut defects and transformation of the gastro-intestinal tract in Tcf4(-/-)/Tcf1(-/-) embryos.	SOX2 CDX1 TBX6	4.93e-05	16	158	3	15057272
Pubmed	Prdm13 is required for Ebf3+ amacrine cell formation in the retina.	SOX2 GAD2 SLC6A9	4.93e-05	16	158	3	29258872
Pubmed	The Lineage Differentiation and Dynamic Heterogeneity of Thymic Epithelial Cells During Thymus Organogenesis.	SOX2 FOXN1 CDX1	4.93e-05	16	158	3	35273595
Pubmed	Cdx2 regulation of posterior development through non-Hox targets.	SOX2 CDX1 TBX6	4.93e-05	16	158	3	19906845
Pubmed	Association of genetic variants with hemorrhagic stroke in Japanese individuals.	SEMA3F SEPTIN9 ATP10A SPTBN5 CELSR1 NUP210	5.11e-05	143	158	6	20198315
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	TBX3 TCOF1 PPFIA1 KIAA1671 TUBGCP6 RMDN3 GSE1 FAM120C SCN5A MTR IRS2 ACTL6B BRD1 PARD3 SIPA1L2 SEZ6L	5.26e-05	1116	158	16	31753913
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	NRDE2 COPA TCOF1 SEPTIN9 PPFIA1 PRDX4 RBM42 PCDHAC2 AP3B1 PRPF8 HEXIM2 DNTTIP1 FAM120C GLYR1 HELZ2 MCAT PARD3 DNMT1	5.50e-05	1371	158	18	36244648
Pubmed	Genetic determinants of P wave duration and PR segment.	TBX3 SCN5A MED13	5.97e-05	17	158	3	24850809
Pubmed	Anticancer drugs induce hypomethylation of the acetylcholinesterase promoter via a phosphorylated-p38-DNMT1-AChE pathway in apoptotic hepatocellular carcinoma cells.	ACHE DNMT1	6.13e-05	3	158	2	26299326
Pubmed	Novel Mode of Defective Neural Tube Closure in the Non-Obese Diabetic (NOD) Mouse Strain.	SOX2 TBX6	6.13e-05	3	158	2	26593875
Pubmed	RyR2 and calpain-10 delineate a novel apoptosis pathway in pancreatic islets.	RYR2 CAPN10	6.13e-05	3	158	2	15044459
Pubmed	The flamingo-related mouse Celsr family (Celsr1-3) genes exhibit distinct patterns of expression during embryonic development.	CELSR1 CELSR3	6.13e-05	3	158	2	11677057
Pubmed	Dysregulation of CDX1, CDX2 and SOX2 in patients with gastric cancer also affects the non-malignant mucosa.	SOX2 CDX1	6.13e-05	3	158	2	23613102
Pubmed	Regulation of renin expression by the orphan nuclear receptors Nr2f2 and Nr2f6.	NR2F6 NR2F2	6.13e-05	3	158	2	22278040
Pubmed	Friend of GATA 2 physically interacts with chicken ovalbumin upstream promoter-TF2 (COUP-TF2) and COUP-TF3 and represses COUP-TF2-dependent activation of the atrial natriuretic factor promoter.	NR2F6 NR2F2	6.13e-05	3	158	2	11382775
Pubmed	Antagonistic Functions of USAG-1 and RUNX2 during Tooth Development.	SOX2 RUNX2	6.13e-05	3	158	2	27518316
Pubmed	Protein expression profiles in murine ventricles modeling catecholaminergic polymorphic ventricular tachycardia: effects of genotype and sex.	RYR2 SCN5A	6.13e-05	3	158	2	32713021
Pubmed	T-box 3 negatively regulates osteoblast differentiation by inhibiting expression of osterix and runx2.	TBX3 RUNX2	6.13e-05	3	158	2	19115250
Pubmed	Knockout of Slo2.2 enhances itch, abolishes KNa current, and increases action potential firing frequency in DRG neurons.	KCNT2 KCNT1	6.13e-05	3	158	2	26559620
Pubmed	TAF12 recruits Gadd45a and the nucleotide excision repair complex to the promoter of rRNA genes leading to active DNA demethylation.	RRN3P2 RRN3	6.13e-05	3	158	2	19217408
Pubmed	Nucleolar stress controls mutant Huntington toxicity and monitors Huntington's disease progression.	RRN3P2 RRN3	6.13e-05	3	158	2	34880223
Pubmed	Low expression of IL-6 and TNF-α correlates with the presence of the nuclear regulators of NF-κB, IκBNS and BCL-3, in the uterus of mice.	NFKBID BCL3	6.13e-05	3	158	2	26442662
Pubmed	Mutations in the gene encoding the basal body protein RPGRIP1L, a nephrocystin-4 interactor, cause Joubert syndrome.	RPGRIP1 NPHP4	6.13e-05	3	158	2	17558407
Pubmed	Chicken ovalbumin upstream promoter-transcription factor members repress retinoic acid-induced Cdx1 expression.	CDX1 NR2F2	6.13e-05	3	158	2	15677473
Pubmed	The nuclear orphan receptor NR2F6 suppresses lymphocyte activation and T helper 17-dependent autoimmunity.	NR2F6 NR2F2	6.13e-05	3	158	2	18701084
Pubmed	HELZ2 promotes K63-linked polyubiquitination of c-Myc to induce retinoblastoma tumorigenesis.	HUWE1 HELZ2	6.13e-05	3	158	2	34761308
Pubmed	Spatiotemporal transcriptomic atlas of mouse organogenesis using DNA nanoball-patterned arrays.	SOX2 GAD2 RUNX2 ROBO2	6.28e-05	47	158	4	35512705
Pubmed	A dorsal-ventral gradient of Wnt3a/β-catenin signals controls mouse hindgut extension and colon formation.	SOX2 CDX1 TBX6	8.45e-05	19	158	3	32156757
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	HDAC9 GPRIN3 NPHP4 ATP10A NEK9 SHROOM4 EEPD1 NUP210 HELZ2 SLX4	9.23e-05	493	158	10	15368895
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	PNPLA4 PPFIA1 PRPF8 ARHGEF17 KIAA1549L PELP1 FAM120C	1.03e-04	234	158	7	36243803
Pubmed	Targeted proteomic analysis of 14-3-3 sigma, a p53 effector commonly silenced in cancer.	RALGPS2 ARHGEF17 GAN IRS2 PARD3	1.06e-04	102	158	5	15778465
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	WDR7 SEPTIN9 SPEG ARHGEF17 MROH1 GSE1 MAST1 SIPA1L2 SEZ6L	1.09e-04	407	158	9	12693553
Pubmed	Evolutionarily conserved requirement of Cdx for post-occipital tissue emergence.	SOX2 CDX1 TBX6	1.15e-04	21	158	3	22675207
Pubmed	RUNX1 maintains the identity of the fetal ovary through an interplay with FOXL2.	RUNX2 NR2F2 RYR2	1.15e-04	21	158	3	31712577
Pubmed	The role of Tal2 and Tal1 in the differentiation of midbrain GABAergic neuron precursors.	SOX2 NKX6-1 TAL1	1.15e-04	21	158	3	24167708
Pubmed	Sequential genome-wide CRISPR-Cas9 screens identify genes regulating cell-surface expression of tetraspanins.	NR2F6 XDH STAB1 KIAA1671 GSE1 PELP1 FAM120C RRN3 EEPD1 IRS2 PARD3 PLK3 SLX4	1.18e-04	832	158	13	36724073
Pubmed	Mechanochemical control of mesenchymal condensation and embryonic tooth organ formation.	SEMA3F HSPG2	1.22e-04	4	158	2	21924961
Pubmed	The adhesion GPCRs CELSR1-3 and LPHN3 engage G proteins via distinct activation mechanisms.	CELSR1 CELSR3	1.22e-04	4	158	2	37224017
Pubmed	A direct fate exclusion mechanism by Sonic hedgehog-regulated transcriptional repressors.	SOX2 NKX6-1	1.22e-04	4	158	2	26293298
Pubmed	Nervous System Regionalization Entails Axial Allocation before Neural Differentiation.	SOX2 CDX1	1.22e-04	4	158	2	30343898
Pubmed	Orphan nuclear receptor chicken ovalbumin upstream promoter-transcription factor II (COUP-TFII) protein negatively regulates bone morphogenetic protein 2-induced osteoblast differentiation through suppressing runt-related gene 2 (Runx2) activity.	RUNX2 NR2F2	1.22e-04	4	158	2	22493443
Pubmed	Perlecan is required for the chondrogenic differentiation of synovial mesenchymal cells through regulation of Sox9 gene expression.	HSPG2 RUNX2	1.22e-04	4	158	2	27238423
Pubmed	Formation and contraction of multicellular actomyosin cables facilitate lens placode invagination.	ARHGEF11 PARD3	1.22e-04	4	158	2	32113830
Pubmed	Developmental expression profiles of Celsr (Flamingo) genes in the mouse.	CELSR1 CELSR3	1.22e-04	4	158	2	11850187
Pubmed	Runx2+ Niche Cells Maintain Incisor Mesenchymal Tissue Homeostasis through IGF Signaling.	SOX2 RUNX2	1.22e-04	4	158	2	32783935
Cytoband	Ensembl 112 genes in cytogenetic band chr19p13	NR2F6 MED16 PLPPR3 IQCN GDF1 SBNO2 CILP2 OR1I1 SLC27A1 MAST1 DNMT1	1.08e-04	797	158	11	chr19p13
GeneFamily	Potassium sodium-activated channel subfamily T	KCNT2 KCNT1	2.97e-05	2	99	2	856
GeneFamily	Adhesion G protein-coupled receptors, subfamily C\|CELSR cadherins	CELSR1 CELSR3	8.87e-05	3	99	2	913
GeneFamily	Adhesion G protein-coupled receptors, subfamily C\|CELSR cadherins	CELSR1 CELSR3	8.87e-05	3	99	2	1189
GeneFamily	PDZ domain containing	ARHGEF11 SHROOM4 MAST1 FRMPD3 PARD3 SIPA1L2	1.88e-04	152	99	6	1220
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	HSPG2 SPEG FSTL4 IGDCC3 ROBO2 ALPK2	2.57e-04	161	99	6	593
GeneFamily	Acyl-CoA synthetase family	SLC27A1 SLC27A5 SLC27A3	3.78e-04	26	99	3	40
GeneFamily	Forkhead boxes	FOXN1 FOXO6 FOXL1	1.68e-03	43	99	3	508
GeneFamily	Nuclear hormone receptors	NR2F6 NR2F2 NR1I3	2.44e-03	49	99	3	71
GeneFamily	T-boxes	TBX3 TBX6	4.29e-03	18	99	2	766
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	FGD2 ARHGEF11 ARHGEF17	5.68e-03	66	99	3	722
GeneFamily	Solute carriers	SLC52A3 SLC6A9 SLC22A18 SLC27A1 SLC25A38 SLC27A5 SLC27A3	6.00e-03	395	99	7	752
GeneFamily	PWWP domain containing	GLYR1 BRD1	6.38e-03	22	99	2	1147
Coexpression	MIKKELSEN_MEF_HCP_WITH_H3K27ME3	SOX2 CDX1 ACHE FSTL4 MATN4 RYR2 CELSR1 SCN5A MAST1 ACTL6B NKX6-1 TAL1 KCNT1 SEZ6L FOXL1	3.15e-06	591	158	15	M2019
Coexpression	MIKKELSEN_MEF_HCP_WITH_H3K27ME3	SOX2 CDX1 ACHE FSTL4 MATN4 RYR2 CELSR1 SCN5A MAST1 ACTL6B NKX6-1 TAL1 KCNT1 SEZ6L FOXL1	3.85e-06	601	158	15	MM866
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GAD2 ACHE FIGN ANKRD55 NR2F2 KCNT2 ROBO2 FRMPD3 PARD3	2.40e-08	187	158	9	ae2ee6f8e5c37cb88a67f3e742cf86e57657bfaf
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	HSPG2 TBX3 RALGPS2 FIGN ARHGEF17 NR2F2 RYR2 MMP17	1.75e-07	170	158	8	5570c0e825bca77613bf0ebde620cf744fa1cb84
ToppCell	droplet-Lung-nan-3m-Myeloid-plasmacytoid_dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FGD2 ACHE IDH3A RUNX2 JAML RIN1 EEPD1 RELL1	2.00e-07	173	158	8	1b9b4e165121b08ef15a93fca6bea875cae69f19
ToppCell	droplet-Lung-nan-3m-Myeloid-Plasmacytoid_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FGD2 ACHE IDH3A RUNX2 JAML RIN1 EEPD1 RELL1	2.00e-07	173	158	8	c25f24d7b672c9686d31ebc8d263042282f520fd
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SOX2 GAD2 RUNX2 ANKRD55 NR2F2 CDCA7 FRMPD3 PARD3	4.43e-07	192	158	8	bf1943715085c4124b1675888b0615c9500ec888
ToppCell	Striatum-Endothelial-ENDOTHELIAL_STALK-Flt1_1\|Striatum / BrainAtlas - Mouse McCarroll V32	XDH ATP10A SLC52A3 SHROOM4 SLC22A18 HELZ2 TAL1	6.05e-07	137	158	7	306b11b3b9e5fd562d845fb5eaa4ac982864efce
ToppCell	LPS-antiTNF-Hematopoietic_Meg-Ery-Mes-Epi-like-Erythroid\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	HDAC9 NR2F6 PNPLA4 SPEG MATN4 RYR2 NUP210	6.05e-07	137	158	7	8e2fa2ef8becace96a68bb85c002329110902fbb
ToppCell	Striatum-Endothelial-ENDOTHELIAL_STALK\|Striatum / BrainAtlas - Mouse McCarroll V32	XDH ATP10A SLC52A3 SHROOM4 SLC22A18 HELZ2 TAL1	6.05e-07	137	158	7	d37f425b13bc046baa1f8619b98a16b936f88ff6
ToppCell	droplet-Fat-SCAT-30m-Myeloid\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NR2F6 FGD2 PCDHAC2 NFKBID KIAA1549L MTR SLC27A5	1.33e-06	154	158	7	73de626b210ec5482ba89a65e784c1e77ff2894e
ToppCell	droplet-Fat-SCAT-30m-Myeloid-myeloid_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NR2F6 FGD2 PCDHAC2 NFKBID KIAA1549L MTR SLC27A5	1.33e-06	154	158	7	56fe9953e58f71626d3ddf63d340ed35dfc4ce9f
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Myocytic\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ARHGEF17 NR2F2 RYR2 SLC6A9 KCNT2 ECRG4 MMP17	1.45e-06	156	158	7	6365b69ede98bc866e996bc52736b00401aacf6f
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Myocytic-Pericyte_2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ARHGEF17 NR2F2 RYR2 SLC6A9 KCNT2 ECRG4 MMP17	1.51e-06	157	158	7	bfec34182f052cf1c0d847ba53ea335d4d1190de
ToppCell	Frontal_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	HDAC9 GAD2 PLPPR3 ANKRD55 NR2F2 DPEP2 SCN5A	1.64e-06	159	158	7	7f29f9dcf25ffa1822b137c571e9ac16defc6292
ToppCell	LPS-IL1RA-Myeloid-Dendritic_cells-pDC\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	HDAC9 FGD2 NFKBID RUNX2 ATP10A MMP17 NLRC3	1.71e-06	160	158	7	dee756a2dc9725520d439e7273c489c2284015d8
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-SPN_Neuron_STR\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GAD2 GPRIN3 NPHP4 RIN1 SCN5A MAST1 NPAS2	2.10e-06	165	158	7	1b7dfa173e83aa8c46a3153a3261866c065c3b73
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-medium_spiny_neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GAD2 GPRIN3 NPHP4 RIN1 SCN5A MAST1 NPAS2	2.10e-06	165	158	7	b4f7d33af7d053ec07b01bd67d861600a9c4822e
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PRDX4 GPRIN3 BCL3 ARHGEF17 ATP10A ROBO2 IRS2	2.28e-06	167	158	7	b4ef07117d14da3d5fbced949e4dfcb01c392295
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PRDX4 GPRIN3 BCL3 ARHGEF17 ATP10A ROBO2 IRS2	2.28e-06	167	158	7	94fc7df7ca55cd722a8dbd153201a29891217473
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PRDX4 GPRIN3 BCL3 ARHGEF17 ATP10A ROBO2 IRS2	2.28e-06	167	158	7	eff3723fe60755272eca237459165e436e919ece
ToppCell	TCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Classical-8\|TCGA-Thryoid / Sample_Type by Project: Shred V9	RUNX2 ARHGEF17 SHROOM4 FAM120C ECRG4 SIPA1L2 MED13	2.37e-06	168	158	7	00646601548b0fee42ae16bfa5e93603bc7c5129
ToppCell	Tracheal-10x5prime-Immune_Myeloid-Dendritic_cell-DC_plasmacytoid\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	FGD2 RUNX2 NPHP4 JAML LDLRAD4 ALPK2 LILRA4	2.37e-06	168	158	7	c34dd4a9c54d8e9c8f118e6a3816548890cb0746
ToppCell	NS-critical-d_0-4-Epithelial-Secretory\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	HSPG2 FOXO6 PRDX4 KIAA1671 SHROOM4 FCGBP NPAS2	2.47e-06	169	158	7	aec97583b23112060437b619cb429dc32f29285f
ToppCell	facs-Large_Intestine-Distal-18m-Epithelial-epithelial_cell_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPG2 TCOF1 ACHE MATN4 CNTLN NPHP4 DNMT1	2.88e-06	173	158	7	a5172dee859bf6c2eed46c48bd64dfef0ff9f28f
ToppCell	facs-Large_Intestine-Distal-18m-Epithelial-Lgr5-_amplifying_undifferentiated_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPG2 TCOF1 ACHE MATN4 CNTLN NPHP4 DNMT1	2.88e-06	173	158	7	639b5b0b33ce5aa0bc26363c059717012ddc14c0
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_SST_CXCL14\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GAD2 NIPAL3 FIGN NR2F2 SCN5A PARD3 SIPA1L2	3.61e-06	179	158	7	c7afbd10072d36a35cd20ae73670d76b9cefd22d
ToppCell	Control-Endothelial_cells-Capillary_endothelial_cells\|Control / group, cell type (main and fine annotations)	TBX3 FSTL4 KIAA1671 SHROOM4 EEPD1 SIPA1L2 TAL1	3.74e-06	180	158	7	b043f9ffb9a4cd427a15bebb86a711c7b08866e8
ToppCell	Control-Myeloid-Dendritic_cells\|Control / group, cell type (main and fine annotations)	HDAC9 FGD2 NFKBID GPRIN3 JAML STAB1 LDLRAD4	3.74e-06	180	158	7	25ad95c3c30e3b82abe93bd77ba003f5c2241f7c
ToppCell	facs-Heart-LV-18m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TBX3 NR2F6 FGD2 RALGPS2 NFKBID RELL1 CHST3	4.02e-06	182	158	7	6dff753d65ba45db81f3cc0c9f59e1779d490955
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ARHGEF17 NR2F2 RYR2 SLC6A9 KCNT2 ECRG4 MMP17	4.17e-06	183	158	7	8a799807fbf24456a9811e0c64068187940a2f71
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ACHE FIGN ANKRD55 NR2F2 KCNT2 ROBO2 PARD3	4.32e-06	184	158	7	32473dbdb2de66391157c5814ef34e790806e4f2
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GAD2 ACHE ANKRD55 NR2F2 KCNT2 FRMPD3 PARD3	4.48e-06	185	158	7	cefd81adb480c027545a5c78dcd05669783717f4
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SOX2 GAD2 ACHE PLPPR3 ZNF385A ANKRD55 NR2F2	4.48e-06	185	158	7	739260f8abebaf10a5cc49d91726278579e26170
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GAD2 NR2F2 CILP2 EEPD1 FRMPD3 PARD3 SEZ6L	4.81e-06	187	158	7	d2ffb2f34f07b0dd5d3cb3ee0275f46ebecf4146
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ACHE FIGN ANKRD55 NR2F2 KCNT2 ROBO2 PARD3	4.98e-06	188	158	7	6ee3f8f94ea7bdf652c9575fc65bff08070093a4
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ACHE IGDCC3 FIGN ANKRD55 NR2F2 KCNT2 PARD3	4.98e-06	188	158	7	c66fccdfe68760b8c3efca77e3c25966dc9a8a5f
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6-Inh_L1_PAX6_CA4\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GAD2 NR2F2 CDCA7 EEPD1 FRMPD3 PARD3 SEZ6L	4.98e-06	188	158	7	ee572246e0c2f41bdbc29a03edc67b831af95c09
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-6_LAMP5_CA13_(Lamp5_Lhx6_1)\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SOX2 SEMA3F GAD2 DDI1 ANKRD55 CDCA7 EEPD1	4.98e-06	188	158	7	3139540a656c0436b2123ea50741ff8d00112165
ToppCell	Control-Myeloid-Transitioning_MDM\|Control / group, cell type (main and fine annotations)	TCOF1 NFKBID GPRIN3 JAML STAB1 PRKAG2 LDLRAD4	5.34e-06	190	158	7	d6fd8c23cde4a10cc1517b6899a5a855fdfff2e2
ToppCell	Control-Endothelial-VE_Venous\|Endothelial / Disease state, Lineage and Cell class	HDAC9 ANKRD55 SHROOM4 GSE1 RELL1 LDLRAD4 NPAS2	5.34e-06	190	158	7	4e30155203b4a8c5e496fcbe9348b67b98ebc625
ToppCell	3'_v3-bone_marrow-Myeloid_Dendritic\|bone_marrow / Manually curated celltypes from each tissue	FGD2 IDH3A RUNX2 JAML RASD1 LDLRAD4 LILRA4	5.34e-06	190	158	7	6892c603037b61ef88d6ca01b7592dc0d347d63b
ToppCell	COVID-19-lung-CD4+_Treg\|COVID-19 / Disease (COVID-19 only), tissue and cell type	GPRIN3 RUNX2 JAML CD5 NUP210 NLRC3 LDLRAD4	5.53e-06	191	158	7	5a4ad5ae5c2dbfb225158cb598ef649c26a48350
ToppCell	Adult-Immune-monocyte-D175\|Adult / Lineage, Cell type, age group and donor	HDAC9 FGD2 NFKBID JAML STAB1 LDLRAD4 SEZ6L	5.53e-06	191	158	7	cbebb4d9550fdcd606cb3685ac9546c6b73fd422
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SOX2 GAD2 NIPAL3 ANKRD55 NR2F2 FRMPD3 PARD3	5.53e-06	191	158	7	7b386512284dfaa0e95358b28ee82632ee965e64
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-3_mon-IPC_like-IPCs\|3_mon / Sample Type, Dataset, Time_group, and Cell type.	HDAC9 SEPTIN9 IGDCC3 GSE1 RASD1 ROBO2 SEZ6L	5.53e-06	191	158	7	e4c1c533771b582e21683dbec6f93a558d865e00
ToppCell	COVID-19-lung-CD4+_Treg\|lung / Disease (COVID-19 only), tissue and cell type	GPRIN3 RUNX2 JAML CD5 NUP210 NLRC3 LDLRAD4	5.53e-06	191	158	7	73ea3078c1f55cd47e4d99e77b3ce4ff17549d49
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-3_mon-IPC_like\|3_mon / Sample Type, Dataset, Time_group, and Cell type.	HDAC9 SEPTIN9 IGDCC3 GSE1 RASD1 ROBO2 SEZ6L	5.53e-06	191	158	7	48cffb55c71bb8b34e926fc461fcd345ce43ea00
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GAD2 ACHE ANKRD55 NR2F2 KCNT2 FRMPD3 PARD3	5.72e-06	192	158	7	3abee376c37c3646da33ac381aa63d50a01607a6
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-DC-DC3-G\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TCOF1 NFKBID IDH3A RUNX2 JAML LDLRAD4 LILRA4	5.92e-06	193	158	7	30abf991ac17c18679ab7d633e7549c0ce841920
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Dendritic\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	HDAC9 FGD2 ZNF385A RUNX2 JAML SEZ6L LILRA4	6.33e-06	195	158	7	4cbc36fb3ef9aef61367d3b37070a9a85fae1418
ToppCell	Control-Lymphoid-T\|Lymphoid / Disease state, Lineage and Cell class	GPRIN3 RUNX2 JAML ANKRD55 RYR2 CD5 LDLRAD4	6.33e-06	195	158	7	6687e579582d7a239bee80846de0cf827a6f6a62
ToppCell	Adult-Immune-monocyte-D122\|Adult / Lineage, Cell type, age group and donor	HDAC9 FGD2 JAML STAB1 DPEP2 PRKAG2 LDLRAD4	6.55e-06	196	158	7	16b0acb6157534938ca83d4e909471e33a7d3c52
ToppCell	IPF-Lymphoid-T\|Lymphoid / Disease state, Lineage and Cell class	GPRIN3 RUNX2 JAML ANKRD55 RYR2 CD5 LDLRAD4	6.55e-06	196	158	7	6e70c48a63d9673eb16b0847c1bd88eecc2f7a3c
ToppCell	COPD-Lymphoid-T\|Lymphoid / Disease state, Lineage and Cell class	GPRIN3 RUNX2 JAML ANKRD55 RYR2 CD5 LDLRAD4	6.55e-06	196	158	7	c9bdd505c3ab380ed7b272aa518df31a0a706a06
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Myeloid-Dendritic\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	HDAC9 FGD2 ZNF385A RUNX2 JAML SEZ6L LILRA4	6.77e-06	197	158	7	89fe4885efc8db142c0dc0506840ae8aceba9ef9
ToppCell	myeloid-pro-pDC\|World / Lineage and Cell class	DYNC2I2 IDH3A RUNX2 CDCA7 RASD1 LDLRAD4 LILRA4	6.77e-06	197	158	7	8918ee006b16f6b86ed33ce1dd5c0f01f51f88f5
ToppCell	Parenchymal-NucSeq-Immune_Myeloid-Macrophage_other-Macro_AW_CX3CR1\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	HDAC9 FGD2 GPRIN3 JAML STAB1 FCGBP LDLRAD4	6.99e-06	198	158	7	732a43061d75bc5e1cf23f5056b72cd10c926668
ToppCell	Bronchial-10x5prime-Stromal-Myofibroblastic\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	SPEG ARHGEF17 NR2F2 RYR2 ECRG4 KCNT1 FOXL1	7.23e-06	199	158	7	ad75e5e26c37a97331164d7f77235ebd9a933a44
ToppCell	Bronchial-10x5prime-Immune_Myeloid-Dendritic_cell\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	HDAC9 ACHE NFKBID RUNX2 JAML LDLRAD4 LILRA4	7.23e-06	199	158	7	946d904a880c0e211861fcec7e120853ffade282
ToppCell	Neuronal-Inhibitory-iA-iA_2(LAMP5)-CA1-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	SOX2 SEMA3F GAD2 ANKRD55 CDCA7 EEPD1 PARD3	7.47e-06	200	158	7	ca5401b76ab014080914bf78042d368cf318effa
ToppCell	Neuronal-Inhibitory-iA-iA_1(SST_PAX6)-PAX6-CDH12-L1-2\|Neuronal / cells hierarchy compared to all cells using T-Statistic	SOX2 GAD2 NR2F2 EEPD1 FRMPD3 PARD3 SEZ6L	7.47e-06	200	158	7	ead9eb579bb25fde05fc15602e3d05ab6617f7ac
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic-Pericyte\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	ARHGEF17 NR2F2 RYR2 SLC6A9 KCNT2 ECRG4 MMP17	7.47e-06	200	158	7	4e1e19214aeebbdca004de7faaf4cc9d18498591
ToppCell	Neuronal-Inhibitory-iA-iA_2(LAMP5)-CA1--L2-6\|Neuronal / cells hierarchy compared to all cells using T-Statistic	SOX2 SEMA3F GAD2 ANKRD55 CDCA7 EEPD1 PARD3	7.47e-06	200	158	7	70c47d3bbe67d88c5b9dff99c33a603d25fa2ab0
ToppCell	Neuronal-Inhibitory-iA\|Neuronal / cells hierarchy compared to all cells using T-Statistic	SOX2 GAD2 ANKRD55 NR2F2 EEPD1 FRMPD3 PARD3	7.47e-06	200	158	7	5ef4a3dc18a44292184a59ced916183c0699b01e
ToppCell	Neuronal-Inhibitory-iA-iA_2(LAMP5)-DBP\|Neuronal / cells hierarchy compared to all cells using T-Statistic	SOX2 GAD2 BCL3 RUNX2 ANKRD55 EEPD1 PARD3	7.47e-06	200	158	7	17ee2ca50a3690531d42dab5858c6ff9d103cae0
ToppCell	Neuronal-Inhibitory-iA-iA_2(LAMP5)-DBP--L1-2\|Neuronal / cells hierarchy compared to all cells using T-Statistic	SOX2 GAD2 BCL3 RUNX2 ANKRD55 EEPD1 PARD3	7.47e-06	200	158	7	05440294290b4f5c63342544170645a759227e00
ToppCell	Neuronal-Inhibitory-iA-iA_2(LAMP5)-CA1\|Neuronal / cells hierarchy compared to all cells using T-Statistic	SOX2 SEMA3F GAD2 ANKRD55 CDCA7 EEPD1 PARD3	7.47e-06	200	158	7	40286010bd17cf9e34ecd5440953b072ebfae208
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic-Pericyte-Pericyte_2\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	ARHGEF17 NR2F2 RYR2 SLC6A9 KCNT2 ECRG4 MMP17	7.47e-06	200	158	7	786f1ae53e60b5ffbf4bfd393d10b802478148b3
ToppCell	Neuronal-Inhibitory-iA-iA_2(LAMP5)-LCP2-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	SOX2 GAD2 RUNX2 ANKRD55 CDCA7 EEPD1 PARD3	7.47e-06	200	158	7	7345cc7dc24b9174541a3e68ecac8c4c092be400
ToppCell	LPS_only-Mesenchymal_myocytic-Pericyte-Pericyte_2\|LPS_only / Treatment groups by lineage, cell group, cell type	ARHGEF17 NR2F2 RYR2 SLC6A9 KCNT2 ECRG4 MMP17	7.47e-06	200	158	7	69edc375d85689300d1dbc1217fedc40063ecdcb
ToppCell	Neuronal-Inhibitory-iA-iA_2(LAMP5)-DBP-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	SOX2 GAD2 BCL3 RUNX2 ANKRD55 EEPD1 PARD3	7.47e-06	200	158	7	0e7a07a7c6d743d9763315c78f1bc1e1867688d8
ToppCell	Control_saline-Endothelial-Endothelial-Vein\|Control_saline / Treatment groups by lineage, cell group, cell type	SEMA3F HDAC9 HSPG2 IGDCC3 NR2F2 STAB1 KIAA1549L	7.47e-06	200	158	7	e5f876910bc8cb390d9b46a48d9b6d4d57235551
ToppCell	Control_saline-Mesenchymal_myocytic-Pericyte-Pericyte_2\|Control_saline / Treatment groups by lineage, cell group, cell type	ARHGEF17 NR2F2 RYR2 SLC6A9 KCNT2 ECRG4 MMP17	7.47e-06	200	158	7	bc8949eb34482aca166c4602ff6ab876cb4c2c3c
ToppCell	Neuronal-Inhibitory-iA-iA_2(LAMP5)-LCP2--L1-4\|Neuronal / cells hierarchy compared to all cells using T-Statistic	SOX2 GAD2 RUNX2 ANKRD55 CDCA7 EEPD1 PARD3	7.47e-06	200	158	7	f268cb1bb047e88913a828614b0a77871f5f8814
ToppCell	Neuronal-Inhibitory-iA-iA_1(SST_PAX6)-PAX6-CDH12\|Neuronal / cells hierarchy compared to all cells using T-Statistic	SOX2 GAD2 NR2F2 EEPD1 FRMPD3 PARD3 SEZ6L	7.47e-06	200	158	7	c74bc12e13d002dedaaf75a2244ec111e47524e1
ToppCell	Neuronal-Inhibitory-iA-iA_2(LAMP5)-LCP2\|Neuronal / cells hierarchy compared to all cells using T-Statistic	SOX2 GAD2 RUNX2 ANKRD55 CDCA7 EEPD1 PARD3	7.47e-06	200	158	7	5ff9ac97ef970b3b74ebb07f62a0a1f4176a10b4
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	ARHGEF17 NR2F2 RYR2 SLC6A9 KCNT2 ECRG4 ROBO2	7.47e-06	200	158	7	67dcbd86fbc79fd585d0793f979e4aac100326c9
ToppCell	Bronchial-NucSeq-Immune_Lymphocytic-T-T_CD4\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	GPRIN3 RUNX2 JAML CD5 NUP210 NLRC3 LDLRAD4	7.47e-06	200	158	7	9de4d6ebb7e9bee5d811519eb05913ef30f70786
ToppCell	Control_saline-Mesenchymal_myocytic-Pericyte\|Control_saline / Treatment groups by lineage, cell group, cell type	ARHGEF17 NR2F2 RYR2 SLC6A9 KCNT2 ECRG4 MMP17	7.47e-06	200	158	7	cb7ef774b6d300f8019c5b16a04e3ebd165e4f1c
ToppCell	LPS-antiTNF-Hematopoietic_Meg-Ery-Mes-Epi-like\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NR2F6 PNPLA4 SPEG MATN4 RYR2 NUP210	9.20e-06	136	158	6	a2063abe2d7c3277bfbe1514c8c66363cf04b248
ToppCell	Frontal_cortex-Endothelial-ENDOTHELIAL_STALK\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	BCL3 ATP10A SLC52A3 SHROOM4 HELZ2 TAL1	1.87e-05	154	158	6	b0735365de153d4586ca17896431d7bd9c7d8eac
ToppCell	Posterior_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	SOX2 GAD2 ANKRD55 NR2F2 SCN5A FRMPD3	1.93e-05	155	158	6	105d59d8a1bb8cb37eef2c1767d737b2108ac7c5
ToppCell	COVID-19-Myeloid-Dendritic_cells\|COVID-19 / group, cell type (main and fine annotations)	HDAC9 GPRIN3 JAML STAB1 PRKAG2 LDLRAD4	2.01e-05	156	158	6	a07a9096799e4ba663841c70035b4b32c1fda4f9
ToppCell	Cerebellum-Endothelial-ENDOTHELIAL_STALK\|Cerebellum / BrainAtlas - Mouse McCarroll V32	XDH ATP10A SLC52A3 SHROOM4 CDCA7 TAL1	2.75e-05	165	158	6	7d319a112b9062efee428bef6f4534d2ce782e04
ToppCell	Posterior_cortex-Neuronal-Inhibitory\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	SOX2 GAD2 ACHE ZNF385A ANKRD55 FRMPD3	2.94e-05	167	158	6	9a84f45345c75f2c8ff38a04245aadee2a26a240
ToppCell	Club_cells-IPF_03\|World / lung cells shred on cell class, cell subclass, sample id	SOX2 IGDCC3 RUNX2 FCGBP RASD1 MUC20	2.94e-05	167	158	6	dbdaaeb3bd9139cb008d9fe24ec031fc5628f136
ToppCell	368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1.5\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	TBX3 EDC4 NR2F2 KIAA1671 SLC27A5 SLC27A3	3.04e-05	168	158	6	94cded2e953c0970bf2f3dbe0ce46bd77a5ed8c7
ToppCell	10x5'-Lung-Myeloid_Dendritic-pDC\|Lung / Manually curated celltypes from each tissue	HDAC9 RUNX2 RASD1 LDLRAD4 ALPK2 LILRA4	3.04e-05	168	158	6	90f713dae3fcbd6ca801a019e3861c263ff3366b
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	HDAC9 FGD2 JAML STAB1 IRS2 PRKAG2	3.04e-05	168	158	6	61a5435b27b01ff1a509ea463a6af220c5d2c9b3
ToppCell	3'-Parenchyma_lung-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs-Plasmacytoid_DCs_L.1.5.1.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FGD2 RUNX2 JAML RASD1 LDLRAD4 LILRA4	3.04e-05	168	158	6	59b698f58cb206f0f8f0e8ad72b445d14ba24728
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	HDAC9 FGD2 JAML STAB1 IRS2 PRKAG2	3.04e-05	168	158	6	26fce414439ccd204e3acb41f2b4f75072df5a26
ToppCell	droplet-Lung-LUNG-1m-Myeloid-Myeloid_Dendritic_Type_1\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GAD2 FGD2 PGGHG NFKBID ZNF385A ANKRD55	3.15e-05	169	158	6	735655e75511c5c41aca667909e8bb52a0ad7fc6
ToppCell	wk_20-22-Mesenchymal-Chondrocyte\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	FSTL4 MATN4 CILP2 ECRG4 NKX6-1 SEZ6L	3.36e-05	171	158	6	d2938639e9a7c349e5a6ec61724222f9d127c89f
ToppCell	Children_(3_yrs)-Immune-dendritic_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	HDAC9 FGD2 RUNX2 ANKRD55 LDLRAD4 LILRA4	3.36e-05	171	158	6	6a5ac0f56bd7b4543be103100fb735ca6bc5b8bf
ToppCell	facs-Marrow-T-cells-3m-Myeloid-CD4+_macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HDAC9 RPGRIP1 RUNX2 JAML EEPD1 RELL1	3.36e-05	171	158	6	6a0fafb8fd9fc7671618eeb2bf528ce8ce86b794
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Vip\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SOX2 GAD2 ANKRD55 NR2F2 KCNT2 SCN5A	3.36e-05	171	158	6	5efd15300f865ebf651e0888265cbd717bc3b9d3
ToppCell	droplet-Spleen-nan-18m-Myeloid-macrophage_dendritic_cell_progenitor\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RUNX2 JAML SLC27A1 EEPD1 RELL1 PARD3	3.36e-05	171	158	6	4e856441063e9825b6f87a1d3dd19c77dae4662c
ToppCell	facs-Marrow-T-cells-3m-Myeloid-macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HDAC9 RPGRIP1 RUNX2 JAML EEPD1 RELL1	3.36e-05	171	158	6	e02b5831768dbb1b68998b672e55c9680ab0cc86
ToppCell	metastatic_Lymph_Node-Myeloid_cells-pDCs\|metastatic_Lymph_Node / Location, Cell class and cell subclass	IDH3A RUNX2 JAML RASD1 LDLRAD4 LILRA4	3.36e-05	171	158	6	1f8e66073088fc1969782e443bf00f8c1877ea91
ToppCell	droplet-Liver-LIVER-30m-Myeloid-plasmacytoid_dendritic_cells\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPGRIP1 RUNX2 JAML RELL1 LDLRAD4 CHST3	3.47e-05	172	158	6	db5a31cafce4346fe459d7f35210823fd7004439
ToppCell	5'-GW_trimst-2-SmallIntestine-Hematopoietic-Myeloid-pDC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	IDH3A RUNX2 JAML RASD1 LDLRAD4 LILRA4	3.47e-05	172	158	6	b84610f1e5889a655652800c2b3270d264bfe1a9
Drug	Proglumide [6620-60-6]; Up 200; 12uM; MCF7; HT_HG-U133A	SEMA3F NR2F6 COPA MED16 SPEG HUWE1 ARHGEF17 STAB1 GLYR1 MMP17	8.28e-07	191	156	10	3861_UP
Drug	LY 294002; Up 200; 10uM; MCF7; HT_HG-U133A	SPEG HUWE1 NEK9 CD5 GLYR1 IRS2 TAL1 FOXL1 TBX6	6.46e-06	189	156	9	5587_UP
Drug	Domperidone maleate; Down 200; 7.4uM; HL60; HT_HG-U133A	NR2F6 DEAF1 SEPTIN9 RBM42 EDC4 RASSF7 GLYR1 PARD3 PLK3	8.67e-06	196	156	9	1301_DN
Drug	Fenbufen [36330-85-5]; Down 200; 15.8uM; MCF7; HT_HG-U133A	SOX2 MED16 ARHGEF17 RYR2 SBNO2 CAPN10 GLYR1 IRS2 MMP17	9.03e-06	197	156	9	3618_DN
Drug	Benfotiamine [22457-89-2]; Down 200; 8.6uM; MCF7; HT_HG-U133A	SOX2 HSPG2 GAD2 COPA MED16 SEPTIN9 BCL3 NEK9 SBNO2	9.03e-06	197	156	9	3931_DN
Drug	Carbachol [51-83-2]; Down 200; 21.8uM; PC3; HT_HG-U133A	SEMA3F HSPG2 SPEG SBNO2 RIN1 GLYR1 NUP210 PLK3 LDLRAD4	9.41e-06	198	156	9	6742_DN
Drug	Drofenine hydrochloride [548-66-3]; Down 200; 11.4uM; PC3; HT_HG-U133A	DEAF1 BCL3 ARHGEF11 NPHP4 NR2F2 SLC22A18 CELSR1 GSE1 BRD1	1.02e-05	200	156	9	7129_DN
Drug	Procainamide	SCN5A DNMT1	4.66e-05	2	156	2	DB01035
Drug	Carcinine [56897-53-1]; Down 200; 22uM; PC3; HT_HG-U133A	SEMA3F HSPG2 PNPLA4 SEPTIN9 CXCL3 SBNO2 CELSR1 NUP210	5.74e-05	193	156	8	4225_DN
Drug	Benfotiamine [22457-89-2]; Up 200; 8.6uM; PC3; HT_HG-U133A	PGGHG ACHE SEPTIN9 XDH ARHGEF17 NEK9 SBNO2 TAL1	6.17e-05	195	156	8	4312_UP
Drug	Repaglinide [135062-02-1]; Up 200; 8.8uM; HL60; HT_HG-U133A	FGD2 FSTL4 ARHGEF11 DPEP2 MMP17 LDLRAD4 SEZ6L CHST3	6.17e-05	195	156	8	6135_UP
Drug	Carbimazole [22232-54-8]; Down 200; 21.4uM; MCF7; HT_HG-U133A	SEMA3F ARHGEF11 RYR2 SBNO2 CAPN10 FAM120C GLYR1 IRS2	6.17e-05	195	156	8	5399_DN
Drug	Picotamide monohydrate [80530-63-8]; Up 200; 10.2uM; PC3; HT_HG-U133A	SEMA3F PNPLA4 MED16 CNTLN ATP10A SBNO2 CELSR3 TBX6	6.17e-05	195	156	8	7140_UP
Drug	Amoxicillin [26787-78-0]; Down 200; 11uM; PC3; HT_HG-U133A	COPA TCOF1 MED16 PPFIA1 NEK9 NR2F2 IRS2 PARD3	6.17e-05	195	156	8	6285_DN
Drug	Sulfadoxine [2447-57-6]; Down 200; 12.8uM; MCF7; HT_HG-U133A	MTG1 HSPG2 COPA MED16 RBM42 NEK9 RASSF7 IRS2	6.39e-05	196	156	8	3547_DN
Drug	Antazoline hydrochloride [2508-72-7]; Up 200; 13.2uM; PC3; HT_HG-U133A	SEMA3F MED16 SEPTIN9 SPEG RIN1 KIAA1549L NUP210 IRS2	6.39e-05	196	156	8	7128_UP
Drug	Alcuronium chloride [15180-03-7]; Up 200; 5.4uM; MCF7; HT_HG-U133A	SEMA3F HDAC9 NIPAL3 NEK9 FAM120C NUP210 IRS2 PLK3	6.39e-05	196	156	8	7345_UP
Drug	Epitiostanol [2363-58-8]; Down 200; 13uM; PC3; HT_HG-U133A	SOX2 MED16 BCL3 CXCL3 RYR2 SBNO2 CAPN10 NPAS2	6.39e-05	196	156	8	4204_DN
Drug	Etodolac [41340-25-4]; Down 200; 14uM; MCF7; HT_HG-U133A	HSPG2 DEAF1 PGGHG SEPTIN9 EDC4 NEK9 GLYR1 PLK3	6.63e-05	197	156	8	2254_DN
Drug	Alclometasone dipropionate [667634-13-2]; Up 200; 7.6uM; MCF7; HT_HG-U133A	MED16 SPEG MMP17 LDLRAD4 SEZ6L CHST3 NPAS2 TBX6	6.63e-05	197	156	8	6094_UP
Drug	Fludrocortisone acetate [514-36-3]; Up 200; 9.4uM; MCF7; HT_HG-U133A	SOX2 HSPG2 XDH SBNO2 STAB1 SPTBN5 FAM120C PLK3	6.63e-05	197	156	8	2328_UP
Drug	Solasodine [126-17-0]; Down 200; 9.6uM; MCF7; HT_HG-U133A	NR2F6 DEAF1 MED16 BCL3 ARHGEF17 SBNO2 GLYR1 PRKAG2	6.63e-05	197	156	8	3924_DN
Drug	Sulfamethoxazole [723-46-6]; Down 200; 15.8uM; PC3; HT_HG-U133A	SEMA3F HSPG2 AP3B1 NPHP4 CXCL3 SBNO2 RIN1 NUP210	6.87e-05	198	156	8	7366_DN
Drug	HA-1077 dihydrochloride; Down 200; 10uM; PC3; HG-U133A	TBX3 TCOF1 SEPTIN9 NEK9 SLC6A9 CD5 GLYR1 MMP17	6.87e-05	198	156	8	436_DN
Drug	Monocrotaline [315-22-0]; Up 200; 12.2uM; MCF7; HT_HG-U133A	SOX2 DEAF1 COPA RALGPS2 ARHGEF17 CELSR3 GLYR1 LDLRAD4	7.11e-05	199	156	8	6771_UP
Drug	Canavanine sulfate monohydrate (L,+) [206996-57-8]; Down 200; 13.6uM; PC3; HT_HG-U133A	SOX2 COPA MED16 CXCL3 SBNO2 CAPN10 PARD3 NPAS2	7.11e-05	199	156	8	4197_DN
Drug	ICI 182,780; Down 200; 1uM; PC3; HT_HG-U133A	DEAF1 PNPLA4 SPEG EDC4 RASSF7 SLC22A18 GLYR1 IRS2	7.11e-05	199	156	8	1205_DN
Drug	Riluzole hydrochloride; Down 200; 14.8uM; PC3; HT_HG-U133A	SEMA3F TCOF1 BCL3 ARHGEF11 RASSF7 CAPN10 SLC22A18 CELSR1	7.11e-05	199	156	8	7365_DN
Drug	Ribavirin [36791-04-5]; Down 200; 16.4uM; PC3; HT_HG-U133A	SEMA3F MED16 SBNO2 GSE1 BRD1 PARD3 PLK3 NPAS2	7.11e-05	199	156	8	7316_DN
Drug	Norgestrel-(-)-D [797-63-7]; Up 200; 12.8uM; MCF7; HT_HG-U133A	RPGRIP1 GAD2 ATP10A ANKRD55 SLC6A9 IRS2 LDLRAD4 TBX6	7.11e-05	199	156	8	3606_UP
Drug	Cotinine (-) [486-56-6]; Up 200; 22.6uM; MCF7; HT_HG-U133A	HSPG2 GAD2 ARHGEF11 ARHGEF17 RYR2 FAM120C IRS2 LDLRAD4	7.11e-05	199	156	8	1511_UP
Drug	Lidoflazine [3416-26-0]; Up 200; 8.2uM; MCF7; HT_HG-U133A	SEMA3F SEPTIN9 RBM42 RASSF7 GLYR1 IRS2 PARD3 LDLRAD4	7.11e-05	199	156	8	6278_UP
Drug	Spectinomycin dihydrochloride [21736-83-4]; Up 200; 9.8uM; HL60; HT_HG-U133A	GAD2 SEPTIN9 NIPAL3 NR2F2 SPTBN5 FAM120C DPEP2 LILRA4	7.37e-05	200	156	8	2987_UP
Disease	Arrhythmogenic Right Ventricular Dysplasia	RYR2 SCN5A	8.20e-05	3	155	2	C0349788
Disease	neuritic plaque measurement, cerebral amyloid angiopathy, neurofibrillary tangles measurement	HDAC9 ECRG4	1.63e-04	4	155	2	EFO_0006790, EFO_0006797, EFO_0006798
Disease	neuritic plaque measurement, cerebral amyloid angiopathy	HDAC9 ECRG4	1.63e-04	4	155	2	EFO_0006790, EFO_0006798
Disease	diastolic blood pressure, systolic blood pressure	HDAC9 TBX3 SPEG RALGPS2 FIGN RYR2 KIAA1671 OR1I1 PELP1 SCN5A TAL1 NPAS2	2.31e-04	670	155	12	EFO_0006335, EFO_0006336
Disease	type 2 diabetes mellitus (implicated_via_orthology)	NR2F6 NR2F2 CAPN10 MTR IRS2	2.37e-04	105	155	5	DOID:9352 (implicated_via_orthology)
Disease	NEURAL TUBE DEFECTS, SUSCEPTIBILITY TO	CELSR1 PARD3	7.52e-04	8	155	2	C3891448
Disease	serum gamma-glutamyl transferase measurement	SEPTIN9 ARHGEF11 RYR2 STAB1 GSE1 PARD3 SIPA1L2 MMP17 TAL1 MED13 NR1I3 ALPK2 DNMT1	1.11e-03	914	155	13	EFO_0004532
Disease	very low density lipoprotein cholesterol measurement, cholesterol:total lipids ratio	KLF14 TSEN54 BCL3 ZNF106 RRN3 HELZ2	1.17e-03	222	155	6	EFO_0008317, EFO_0020943
Disease	Odontome	TBX3 RUNX2	1.20e-03	10	155	2	C0524730
Disease	Tooth Abnormalities	TBX3 RUNX2	1.20e-03	10	155	2	C0040427
Disease	systemic juvenile idiopathic arthritis	HDAC9 SLC6A9 FOXL1	1.22e-03	40	155	3	EFO_1001999
Disease	reticulocyte count	SEMA3F GAD2 MED16 SEPTIN9 KLF14 PLPPR3 PRPF8 ANKRD55 SBNO2 EEPD1 MAST1 IRS2 DNMT1 TBX6	1.27e-03	1045	155	14	EFO_0007986
Disease	total hip arthroplasty, osteoarthritis	RUNX2 ECRG4 CHST3	1.40e-03	42	155	3	EFO_0009806, MONDO_0005178
Disease	osteoarthritis, hip	HDAC9 RUNX2 ECRG4 CHST3	1.43e-03	92	155	4	EFO_1000786
Disease	Tachycardia, Ventricular	RYR2 SCN5A	1.46e-03	11	155	2	C0042514
Disease	Long QT Syndrome	RYR2 SCN5A	1.46e-03	11	155	2	C0023976
Disease	Abnormality of the dentition	ABHD17C ROBO2	1.75e-03	12	155	2	HP_0000164
Disease	ascorbic acid 2-sulfate measurement	DEAF1 RRN3P2	2.06e-03	13	155	2	EFO_0800169
Disease	eosinophil count	GAD2 PLPPR3 BCL3 RUNX2 SBNO2 CILP2 CELSR1 CD5 GSE1 PELP1 HELZ2 ECRG4 EXOC2 MMP17 LDLRAD4 ALPK2 TBX6	2.18e-03	1488	155	17	EFO_0004842
Disease	cortical thickness	HDAC9 HSPG2 RALGPS2 RUNX2 NR2F2 STAB1 ZNF106 CELSR1 GLYR1 ROBO2 EXOC2 PRKAG2 PARD3 FOXL1	2.28e-03	1113	155	14	EFO_0004840
Disease	Schizophrenia	HDAC9 GAD2 ACHE ARHGEF11 SBNO2 CFAP65 SLC6A9 MTR MCAT BRD1 DNMT1 NPAS2	2.51e-03	883	155	12	C0036341
Disease	very low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio	KLF14 TSEN54 ZNF106 RRN3 EEPD1 HELZ2	2.79e-03	264	155	6	EFO_0008317, EFO_0020944
Disease	Acute Cerebrovascular Accidents	HDAC9 TBX3 PRPF8	2.90e-03	54	155	3	C0751956
Disease	cardiovascular disease	SEPTIN9 KLF14 FIGN ABHD17C SPTBN5 PRKAG2 SIPA1L2 DNMT1	2.96e-03	457	155	8	EFO_0000319
Disease	Spondyloepiphyseal Dysplasia	HSPG2 CHST3	3.13e-03	16	155	2	C0038015
Disease	Spondyloepiphyseal Dysplasia Tarda, X-Linked	HSPG2 CHST3	3.13e-03	16	155	2	C3541456
Disease	Schwartz-Jampel Syndrome, Type 1	HSPG2 CHST3	3.13e-03	16	155	2	C4551479
Disease	Schwartz-Jampel Syndrome	HSPG2 CHST3	3.13e-03	16	155	2	C0036391
Disease	Melnick-Needles Syndrome	HSPG2 CHST3	3.13e-03	16	155	2	C0025237
Disease	Van Buchem disease	HSPG2 CHST3	3.54e-03	17	155	2	C0432272
Disease	pain	FOXO6 SEPTIN9 ABHD17C ROBO2 CHST3	3.84e-03	196	155	5	EFO_0003843
Disease	Cerebrovascular accident	HDAC9 TBX3 PRPF8	4.29e-03	62	155	3	C0038454
Disease	neuroimaging measurement	HDAC9 RALGPS2 RUNX2 ARHGEF11 NR2F2 ZNF106 CELSR1 SLC27A1 ROBO2 EXOC2 PRKAG2 PARD3 FOXL1	4.32e-03	1069	155	13	EFO_0004346
Disease	osteochondrodysplasia (is_implicated_in)	HSPG2 CHST3	4.42e-03	19	155	2	DOID:2256 (is_implicated_in)
Disease	Osteochondrodysplasias	HSPG2 CHST3	4.42e-03	19	155	2	C0029422
Disease	Dyschondroplasias	HSPG2 CHST3	4.42e-03	19	155	2	C0013366
Disease	very low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio	KLF14 TSEN54 BCL3 ZNF106 EEPD1 HELZ2	4.49e-03	291	155	6	EFO_0008317, EFO_0020946
Disease	triglycerides:total lipids ratio, intermediate density lipoprotein measurement	KLF14 TSEN54 ZNF106 RRN3	4.59e-03	127	155	4	EFO_0008595, EFO_0020947
Disease	colorectal cancer	TBX3 CDX1 FOXO6 RUNX2 SBNO2 KCNT1 SLC27A5 FOXL1 CHST3	4.78e-03	604	155	9	MONDO_0005575
Disease	Multiple Epiphyseal Dysplasia	HSPG2 CHST3	4.90e-03	20	155	2	C0026760
Disease	Osteoarthritis of hip	HDAC9 RUNX2	4.90e-03	20	155	2	C0029410
Disease	freckles	EXOC2 PARD3	4.90e-03	20	155	2	EFO_0003963
Disease	cortical surface area measurement	HDAC9 PPFIA1 RALGPS2 CNTLN NR2F2 ZNF106 CELSR1 ROBO2 ACTL6B EXOC2 PRKAG2 BRD1 PARD3 FOXL1 TBX6	4.93e-03	1345	155	15	EFO_0010736

Protein segments in the cluster

Peptide	Gene	Start	Entry
TPDSHMTPAPLALRA	nan	101	Q9H8V8
AVMAAAAGSPLSLRP	ZNF385A	336	Q96PM9
GAASVGMHLLSPPSR	ACHE	236	P22303
HIPDLSSFAMPLLDG	PRKAG2	36	Q9UGJ0
EEASGMHLPERPAAA	BRD1	676	O95696
ADFDVTGPHAPILAM	BTNL10	31	A8MVZ5
PMAHDITATPAGPSL	CDX1	226	P47902
MAASPARPAVLALTG	ECRG4	1	Q9H1Z8
HAPLLSAPMGSRRLE	CNTLN	76	Q9NXG0
VAARMRHIPLAPGSD	DNMT1	1421	P26358
MSPGVFSRHLPKDAR	ALPK2	751	Q86TB3
ALHVPRDGAEVMSPL	ACTL6B	71	O94805
HTTDDLRMSSLPPLG	GSE1	226	Q14687
EAVRNATRHPGAAPM	ARHGEF11	1076	O15085
PALEGALHRSSMQPD	CD5	466	P06127
RVLSMPPVAGTACHA	CAPN10	436	Q9HC96
NGRLPLHAATAEPDM	ANKRD55	126	Q3KP44
VRGSHGEPDASLMPR	CELSR1	2781	Q9NYQ6
RAHSSPEMRAPGSLK	CFAP157	491	Q5JU67
MAHATLSAAPSNPRL	CXCL3	1	P19876
MGSTLGCHRSIPRDP	EEPD1	1	Q7L9B9
EHTLLEGLSAPAPMS	ATP10A	1381	O60312
PALSPSLMADLEGLH	AP3B1	836	O00203
PSPMASATERLHQDL	RASSF7	231	Q02833
SALSSAAAGPRPMAL	RBM42	171	Q9BTD8
TAPLLAAAGLHAAPM	NR2F6	256	P10588
RPDGQPATREHLLMA	HSPG2	1066	P98160
PDGQPATREHLLMAL	HSPG2	1471	P98160
SGMATIRHPTPLALG	HSPG2	3741	P98160
VAPFARRPSVHSDLM	RASD1	246	Q9Y272
SMPLHVAPLLAAAGL	NR2F2	261	P24468
VAPLLAAAGLHASPM	NR2F2	266	P24468
MRSAAGTPVPSAHLD	EDC4	1246	Q6P2E9
ALLGPADPSASSRHM	IQCN	1161	Q9H0B3
DSITPLLGHLPSDVM	NPAS2	111	Q99743
PPVHRMLAGSDAIIR	ARHGEF17	1901	Q96PE2
LAAMALFSPDRPGVT	NR1I3	266	Q14994
RGVAMVHPLLPGSST	NUP210	941	Q8TEM1
GSPALIRSMLLSNPH	DDI1	141	Q8WTU0
PLPGHLVDMSGTRTL	PCDHB13	731	Q9Y5F0
VVGPLHAMPATDLSA	FIGN	701	Q5HY92
GMAALPRLIAFTSEH	GAD2	266	Q05329
TKEGAAHPPLRLRSM	LILRA4	356	P59901
APATLPVMQEEHGSR	NIPAL3	376	Q6P499
LMIRHFRLEPGGSPS	IGDCC3	96	Q8IVU1
ADVGSLRAMASPPLD	MATN4	176	O95460
CLSTTPPGDMAHARV	KIAA1671	631	Q9BY89
RLAMTPTERPHGSDI	NEK9	681	Q8TD19
MELLHPLGRDSPIAG	MCEE	96	Q96PE7
AMESGALARLTGPAH	NLRC3	586	Q7RTR2
PHMLPEDGANLSSAR	MFF	211	Q9GZY8
TEVPAMTLAPGHAAL	MUC20	41	Q8N307
VVPGPSLEVARAHML	NFKBID	21	Q8NI38
HPLALQLDRTEGSMP	CFAP65	1041	Q6ZU64
RALMHAAAPGAADLP	GDF1	321	P27539
EGPARLPVHSIIASM	KCNT1	636	Q5JUK3
AGEAALTRMPSSVPL	DYNC2I2	366	Q96EX3
SVMLDLDVLRGHPPA	MTG1	316	Q9BT17
GLHSPMLDLDNDTRP	EXOC2	401	Q96KP1
LRSGMESILPPSAHE	PNPLA4	91	P41247
LLPSDGSEHSQPIMA	FAM151B	61	Q6UXP7
AHPISLMTLPGEAGA	FOXO6	376	A8MYZ6
IALGDAVNHPTPMAA	GLYR1	511	Q49A26
ILSHPALPGTEEAMF	NRDE2	456	Q9H7Z3
PHSPAREVDRLGVMT	PPFIA1	706	Q13136
HMVLGALSPEAEPNT	TUBGCP6	1276	Q96RT7
RMAESTGPEPAQLHD	KIAA1549L	1666	Q6ZVL6
GPSRLPVHSIIASMG	KCNT2	581	Q6UVM3
GDTHRAMLPSPLNVR	PGGHG	51	Q32M88
GSLLAARDTEMHPIP	OR1I1	326	O60431
ALGPMSHLLPSERLE	MROH1	246	Q8NDA8
PALFRDISMNHLPGL	PELP1	166	Q8IZL8
ARVPHSLDLSSPNMA	HUWE1	2226	Q7Z6Z7
TALSVMIPAVDPHGS	MAST1	916	Q9Y2H9
MIPAVDPHGSSPLAS	MAST1	921	Q9Y2H9
SRLRLPEMVGHPAFA	NPHP4	341	O75161
RLSPSMGHPLEVGLA	MED16	456	Q9Y2X0
MEQAGTRPAATEHPR	PCDHAC2	1	Q9Y5I4
SGAFHTRLMEPAVEP	MCAT	266	Q8IVS2
TRLSLEGLPSLPSMH	IRS2	891	Q9Y4H2
TPIAAGHPSMNLLLR	IDH3A	101	P50213
VGAVLPGPMLHRALS	GLYCTK	46	Q8IVS8
RSHVEPSERAAVAMP	DMRTB1	141	Q96MA1
PRVTAVAVMAAEPGH	DEAF1	61	O75398
GDAHLLMSIPSPFRG	FCGBP	4966	Q9Y6R7
AAFHPTMPLIVSGAD	COPA	211	P53621
PGHTRAGLEMSLRAA	FRMPD3	936	Q5JV73
PLSMPRINHGVLSAE	GAN	311	Q9H2C0
VAASLRCHAEGIPMP	FSTL4	356	Q6MZW2
PASPLMHIEGFLAAL	DDX11L8	561	A8MPP1
DGEPHIPSLLSMSTR	FAM120C	576	Q9NX05
LHSPLMSGLRVAFPD	ABHD17C	231	Q6PCB6
EVMALPKPGGAHSLA	MAN2C1	636	Q9NTJ4
AAPQDMRAHTSIPLL	FGD2	581	Q7Z6J4
MSHLFDPRLPALAAS	FOXL1	1	Q12952
RALTTLGAPRAHTMP	DPEP2	41	Q9H4A9
LVSMSAGAVVHRRPP	KLF14	16	Q8TD94
LVDGRHSPPMVRSVA	PRPSAP2	221	O60256
MAALGVAEAVAAPHP	DNAAF5	1	Q86Y56
SSPAASVLPHPAMDR	HDAC9	611	Q9UKV0
LSIDRMEHPSSPRGA	CELSR3	2326	Q9NYQ7
LVTTDDMHPFLAPAG	HELZ2	1621	Q9BYK8
AAGRDLIHTPLTMPA	GPRIN3	116	Q6ZVF9
LVTAGASPMALDRHG	BCL3	191	P20749
PVLDTLAMLTAHRAG	SCNM1	51	Q9BWG6
SPAMRGSTPLDVAAA	RYR2	2231	Q92736
MPLHVRRSSDPALIG	PARD3	136	Q8TEW0
LDDSVMEPHAPSRGQ	RALGPS2	371	Q86X27
MAATTPSRPAGHRLP	ODF3L2	271	Q3SX64
PHVAFRAPASVGMSL	MEIS3P1	251	A6NDR6
LSDLGRIPHPSMRVG	RUNX2	246	Q13950
MAAPLLHTRLPGDAA	RRN3	1	Q9NYV6
TSDPGRHVMLLRAVP	RMDN3	56	Q96TC7
AEVPEPAAPSRLHMS	SOX2	281	P48431
AAAALHMLRTEPPGT	RIN1	76	Q13671
SAILSMLRGAPDSAP	PSAPL1	116	Q6NUJ1
PRRPDSGDVTVMDLH	SEZ6L	396	Q9BYH1
MSHLVDPTSGDLPVR	RPGRIP1	1	Q96KN7
VSALPGMEAPLSHLE	SLC52A3	196	Q9NQ40
LPHRAPDFAMSAVLG	TBX3	21	O15119
AVHAALFPPLSMSAP	SEMA3F	701	Q13275
MASDSRHTLLRAPAP	TSEN54	306	Q7Z6J9
MEALPLLAATTPDHG	PRDX4	1	Q13162
TAHPRIAPKASMAGA	TCOF1	1026	Q13428
HGINDILSRPSMPVA	NKX6-1	96	P78426
PRDSPLGHDTVRALM	MMP17	146	Q9ULZ9
LEGRDAAEASMAPPH	TAL1	16	P17542
SPPELTVHVGDSALM	JAML	26	Q86YT9
PARTMHDTLLPDGDL	FOXN1	511	O15353
RHDSGGSLPLTPRME	HEXIM2	36	Q96MH2
PPATAFEGHMLLSGL	MTR	346	Q99707
ATSPGSHLLRPVMLE	SCN5A	611	Q14524
PATGHSLRPLDIEFM	SEPTIN9	416	Q9UHD8
PRAHPAPSMGSLRNE	SIPA1L2	1531	Q9P2F8
LASMPHPLRSRAFSE	SHROOM4	1046	Q9ULL8
LEDMLRSLHAGPPSE	SBNO2	1316	Q9Y2G9
LGVHQVPASTRDPAM	MED13	306	Q9UHV7
FASRLPGALMHTLPA	SLC22A18	121	Q96BI1
LRGHPPTALESVMLG	SLC25A38	116	Q96DW6
MAGQPHSPRELLGAA	SPTBN5	1	Q9NRC6
ALSRSEMEPGAAVPA	SLX4	426	Q8IY92
HSGPLRVAMKFPARS	CDCA7	66	Q9BWT1
HLAGARDATPTEEPM	CILP2	16	Q8IUL8
PAVAGPRRHVLLMAT	CHST3	126	Q7LGC8
LVLGLHRASEMAGPP	PRPF8	1051	Q6P2Q9
MRTSVGHQDARPEAP	PLK3	376	Q9H4B4
RPLGHRTGTLEFMAP	SPEG	3116	Q15772
PPGHILSSDRAAAGM	DNTTIP1	171	Q9H147
AGMAAVADPHSLLDP	SLC27A1	551	Q6PCB7
RAGMAALVLRPPHAL	SLC27A3	586	Q5K4L6
PHGRGMPLAHSVLSS	SLC27A5	206	Q9Y2P5
SAPSLDDPARRHMTI	PLPPR3	381	Q6T4P5
MAPRALPGSAVLAAA	RELL1	1	Q8IUW5
SMLGSLRPAHLGPCS	TTC5	291	Q8N0Z6
ARPRMAAAHGPVAPS	SLC6A9	11	P48067
LASDLPNLGPLRTMH	STAB1	1806	Q9NY15
SPMARRHGIPGALTL	SCART1	541	Q4G0T1
RPLPHLAADMQASGE	XDH	576	P47989
DDPRSHRMLLPSGSL	ROBO2	76	Q9HCK4
SGMEAAPRTLAAHPP	TBX6	51	O95947
MAAPLLHTRLPGDAA	RRN3P2	1	A6NIE6
SAEMPLILTDHPGRT	TASOR2	1476	Q5VWN6
ALLMHPAPGAVDADS	UHRF1BP1	881	Q6BDS2
MGLPLSPAADSARSA	WDR7	1241	Q9Y4E6
MTSAASPHPGLLLDL	ZNF106	656	Q9H2Y7
SAAPRLGASEIMHAP	LDLRAD4	121	O15165