Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ATP-dependent activity	APPBP2 DHX40 RSF1 DDX42 ABCB6 ATP10D MYO5C BLM DNAH12 STARD9 SHOC1 NAV1 CHD6 KIF2A ATP12A ATP1A4 KIF13A TDRD12	1.27e-06	614	154	18	GO:0140657
GeneOntologyMolecularFunction	ATP hydrolysis activity	DHX40 RSF1 DDX42 ABCB6 ATP10D BLM DNAH12 SHOC1 NAV1 CHD6 KIF2A ATP12A ATP1A4 KIF13A TDRD12	1.71e-06	441	154	15	GO:0016887
GeneOntologyMolecularFunction	microtubule motor activity	APPBP2 DNAH12 STARD9 KIF2A KIF13A	2.07e-04	70	154	5	GO:0003777
GeneOntologyMolecularFunction	cytoskeletal motor activity	APPBP2 MYO5C DNAH12 STARD9 KIF2A KIF13A	3.09e-04	118	154	6	GO:0003774
GeneOntologyMolecularFunction	ribonucleoside triphosphate phosphatase activity	DHX40 RSF1 DDX42 ABCB6 DNM1L ATP10D BLM DNAH12 SHOC1 NAV1 CHD6 KIF2A ATP12A ATP1A4 KIF13A TDRD12	3.31e-04	775	154	16	GO:0017111
GeneOntologyMolecularFunction	microtubule binding	APPBP2 DCDC1 MAP6 DLGAP5 DNM1L CLIP4 STARD9 KIF2A KIF13A	6.61e-04	308	154	9	GO:0008017
GeneOntologyMolecularFunction	pyrophosphatase activity	DHX40 RSF1 DDX42 ABCB6 DNM1L ATP10D BLM DNAH12 SHOC1 NAV1 CHD6 KIF2A ATP12A ATP1A4 KIF13A TDRD12	7.80e-04	839	154	16	GO:0016462
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides	DHX40 RSF1 DDX42 ABCB6 DNM1L ATP10D BLM DNAH12 SHOC1 NAV1 CHD6 KIF2A ATP12A ATP1A4 KIF13A TDRD12	7.90e-04	840	154	16	GO:0016817
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	DHX40 RSF1 DDX42 ABCB6 DNM1L ATP10D BLM DNAH12 SHOC1 NAV1 CHD6 KIF2A ATP12A ATP1A4 KIF13A TDRD12	7.90e-04	840	154	16	GO:0016818
GeneOntologyMolecularFunction	SUMO polymer binding	GCNA CASP8AP2	8.69e-04	6	154	2	GO:0032184
GeneOntologyCellularComponent	nuclear body	GCNA CASP8AP2 IL16 FBLL1 TCF20 NT5C3A AHCTF1 PARP3 DDX42 IFI16 BOLA3 UBOX5 ELL3 HIRA BLM SART1 SATB1 CBX6 RBM19 MDC1 KIF2A WDFY3 HEATR5B S100PBP	6.24e-08	903	156	24	GO:0016604
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	RALGAPA1 ERBB2 TCF20 MAP3K20 CAPZB PSD3 DNM1L KIAA0753 FSIP2 PJA2 ANLN STARD9 TBC1D1 NAV1 TJP2 KMT2A PRKCI KIF2A KIF13A BICC1 DOP1A ZC3HAV1	5.15e-11	861	156	22	36931259
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	RPL28 TCF20 COPG1 DHX40 AHCTF1 DLGAP5 RSF1 MAP3K20 CAPZB IFI16 MTPAP HIRA RALY BLM SART1 CLIC1 ANLN RBM19 MDC1 EIF2B5 SMARCC1 KIF2A WDFY3 CCDC86 GOT2 SORD ZC3HAV1	7.30e-11	1353	156	27	29467282
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	TCF20 DLGAP5 USP24 IQCN IFI16 CCNK BLM SART1 ANLN MDC1 EIF2B5 TJP2 SMARCC1 KMT2A OXSR1 ATM CCDC86 ZC3HAV1	1.42e-08	774	156	18	15302935
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	RPL28 MYLK TRO RSF1 DDX42 CAPZB MYNN RALY SART1 DOK4 STARD9 FUNDC2 SMARCC1 KMT2A PPP1R9B CHD6 ATM EMC2 ATP12A ATP1A4 TMPRSS7 HDGFL2 SLC25A31 DOP1A	3.11e-08	1442	156	24	35575683
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	TCF20 COPG1 AHCTF1 RSF1 DDX42 USP24 BLM SART1 PNPT1 MDC1 TJP2 SMARCC1 KMT2A ATM CCDC86 ZC3HAV1	4.65e-08	653	156	16	22586326
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	RALGAPA1 CASP8AP2 RPL28 AHCTF1 DDX42 APAF1 PSD3 RTN4IP1 CPD EXT2 MRPL45 KIAA0753 RALY BLM PJA2 PNPT1 CLPTM1L TRABD PRKCI ATM EMC2 HDGFL2 SOAT1 ZC3HAV1	5.52e-08	1487	156	24	33957083
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	TCF20 AHCTF1 DLGAP5 RSF1 HIRA BLM FSIP2 SATB1 ANLN MDC1 SMARCC1 KMT2A CHD6 CCDC86 HDGFL2	1.15e-07	608	156	15	36089195
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	CASP8AP2 TCF20 RSF1 DDX42 DNM1L RNF114 IFI16 CCNK RALY BLM SART1 CLIC1 MDC1 SMARCC1 KMT2A OXSR1 ATM HDGFL2 SORD	1.63e-07	1014	156	19	32416067
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	CASP8AP2 TICRR RPL28 TCF20 AHCTF1 DLGAP5 DDX42 IFI16 HIRA RALY BLM SART1 MDC1 SMARCC1 KMT2A CHD6 CCDC86 HDGFL2 NAIF1 SOAT1 ZC3HAV1	3.73e-07	1294	156	21	30804502
Pubmed	Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.	PRPSAP2 COPG1 DLGAP5 USP24 DNM1L CPD EXT2 RNF114 BOLA3 MTPAP SART1 CLPTM1L ANLN MDC1 PRKCI OXSR1 CCDC86 SOAT1 GOT2 SORD ZC3HAV1	3.88e-07	1297	156	21	33545068
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	RPL28 COPG1 DDX42 CAPZB DNM1L RALY SART1 CLPTM1L CLIC1 STARD9 RBM19 MDC1 EIF2B5 SMARCC1 PRKCI KIF2A ATM EMC2 CCDC86 SOAT1 GOT2 ZC3HAV1	4.45e-07	1425	156	22	30948266
Pubmed	Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.	TCF20 AHCTF1 DDX42 IFI16 CCNK RALY BLM SART1 MDC1 HDGFL2	6.70e-07	283	156	10	30585729
Pubmed	Alterations in p53, BRCA1, ATM, PIK3CA, and HER2 genes and their effect in modifying clinicopathological characteristics and overall survival of Bulgarian patients with breast cancer.	ERBB2 PIK3CA ATM	8.79e-07	5	156	3	20177704
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	ERBB2 ISCA1 NT5C3A AHCTF1 DNM1L RTN4IP1 CPD MRPL45 MTPAP RALY BLM PNPT1 CLPTM1L TRABD NFX1 NAV1 FUNDC2 PRKCI KIF2A EMC2 SOAT1 ZC3HAV1	9.98e-07	1496	156	22	32877691
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	FBLL1 DHX40 AHCTF1 MAP3K20 ABCB6 CCNK MTPAP HIRA BLM CLPTM1L CLIC1 ANLN RBM19 MDC1 NFX1 KMT2A CHD6 KIF2A HEATR5B CCDC86 HDGFL2 ZC3HAV1	1.01e-06	1497	156	22	31527615
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	FBLL1 TCF20 MAP6 DDX42 CAPZB MRPL45 CCNK HIRA RALY BLM SART1 PNPT1 SMARCC1 CHD6 KIF2A SRPX ATM CCDC86	1.92e-06	1082	156	18	38697112
Pubmed	MYC multimers shield stalled replication forks from RNA polymerase.	RALGAPA1 RPL28 FBLL1 TCF20 DHX40 DLGAP5 DDX42 BLM SART1 CLIC1 ANLN RBM19 MDC1 SMARCC1 KIF2A CCDC86 SOAT1	2.45e-06	989	156	17	36424410
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	UBR2 APPBP2 TCF20 TRO PSD3 PJA2 STARD9 TBC1D1 NAV1 CHD6 PDZD2	2.52e-06	407	156	11	12693553
Pubmed	A probability-based approach for high-throughput protein phosphorylation analysis and site localization.	AHCTF1 DLGAP5 RSF1 USP24 MAP3K20 IFI16 BLM ANLN TJP2 STK39 KIF13A ZC3HAV1	3.15e-06	503	156	12	16964243
Pubmed	Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.	TCF20 DDX42 CCNK HIRA SART1 ANLN MDC1 SMARCC1 KMT2A	3.72e-06	268	156	9	33640491
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	PRPSAP2 COPG1 MAP6 UFC1 USP24 ADGRB3 PSD3 SRCIN1 RALY PJA2 ELFN1 TMCC2 SLC4A10 NAV1 TJP2 PPP1R9B KIF2A EMC2	3.93e-06	1139	156	18	36417873
Pubmed	Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant.	RALGAPA1 TNC CAPZB DNM1L OPA3 SART1 ELFN1 STARD9 TJP2 PPP1R9B STK39	4.25e-06	430	156	11	32581705
Pubmed	Mutational profiling of kinases in human tumours of pancreatic origin identifies candidate cancer genes in ductal and ampulla of vater carcinomas.	ERBB2 PIK3CA ATM	7.29e-06	9	156	3	20838624
Pubmed	The histone demethylase LSD1/KDM1A promotes the DNA damage response.	GMNN MDC1 ATM	7.29e-06	9	156	3	24217620
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	FBLL1 TCF20 AHCTF1 USP24 CAPZB CCNK ANLN MDC1 TJP2 SMARCC1 KMT2A ZC3HAV1	7.63e-06	549	156	12	38280479
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	TICRR MAP6 AHCTF1 DLGAP5 DDX42 DNM1L RTN4IP1 UBOX5 KIAA0753 TMEM98 ANLN NFX1 TJP2 SMARCC1 KIF2A KIF13A BICC1	8.19e-06	1084	156	17	11544199
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	CASP8AP2 APAF1 ADGRB3 PSD3 TBC1D1 TMCC2 CHD6 WDFY3	8.64e-06	225	156	8	12168954
Pubmed	TWIST1 and chromatin regulatory proteins interact to guide neural crest cell differentiation.	TCF20 RALY RBM19 EIF2B5 NAV1 CHD6	1.02e-05	109	156	6	33554859
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	RPL28 AHCTF1 MAP3K20 CAPZB ITGA6 IFI16 MTPAP RALY SART1 CLIC1 ANLN RBM19 MDC1 NAV1 TJP2 PPP1R9B KIF2A ZC3HAV1	1.49e-05	1257	156	18	36526897
Pubmed	Genetic variants in apoptosis and immunoregulation-related genes are associated with risk of chronic lymphocytic leukemia.	IL16 APAF1 GMNN NOD2 MDC1 ATM ENO2	1.74e-05	179	156	7	19074885
Pubmed	In situ single-cell analysis identifies heterogeneity for PIK3CA mutation and HER2 amplification in HER2-positive breast cancer.	ERBB2 PIK3CA	2.00e-05	2	156	2	26301495
Pubmed	Interplay between the DNA damage proteins MDC1 and ATM in the regulation of the spindle assembly checkpoint.	MDC1 ATM	2.00e-05	2	156	2	24509855
Pubmed	Correlation between SNPs of PIK3CA, ERBB2 3'UTR, and their interactions with environmental factors and the risk of epithelial ovarian cancer.	ERBB2 PIK3CA	2.00e-05	2	156	2	33834328
Pubmed	PIK3CA mutations and their response to neoadjuvant treatment in early breast cancer: A systematic review and meta-analysis.	ERBB2 PIK3CA	2.00e-05	2	156	2	29575819
Pubmed	PIK3CA mutations are associated with reduced pathological complete response rates in primary HER2-positive breast cancer: pooled analysis of 967 patients from five prospective trials investigating lapatinib and trastuzumab.	ERBB2 PIK3CA	2.00e-05	2	156	2	27177864
Pubmed	Regulation of OSR1 and the sodium, potassium, two chloride cotransporter by convergent signals.	STK39 OXSR1	2.00e-05	2	156	2	24191005
Pubmed	PIK3CA mutations in Peruvian patients with HER2-amplified and triple negative non-metastatic breast cancers.	ERBB2 PIK3CA	2.00e-05	2	156	2	25467032
Pubmed	Characterization of SPAK and OSR1, regulatory kinases of the Na-K-2Cl cotransporter.	STK39 OXSR1	2.00e-05	2	156	2	16382158
Pubmed	Genetic Alterations Detected by Circulating Tumor DNA in HER2-Low Metastatic Breast Cancer.	ERBB2 PIK3CA	2.00e-05	2	156	2	37265453
Pubmed	A structural basis for the regulation of the LIM-homeodomain protein islet 1 (Isl1) by intra- and intermolecular interactions.	LHX3 ISL1	2.00e-05	2	156	2	23750000
Pubmed	SATB-1 and Her2 as predictive molecular and immunohistochemical markers for urothelial cell carcinoma of the bladder.	ERBB2 SATB1	2.00e-05	2	156	2	33285627
Pubmed	Ternary complex of Kif2A-bound tandem tubulin heterodimers represents a kinesin-13-mediated microtubule depolymerization reaction intermediate.	KIF2A KIF13A	2.00e-05	2	156	2	29980677
Pubmed	A distal modular enhancer complex acts to control pituitary- and nervous system-specific expression of the LHX3 regulatory gene.	LHX3 ISL1	2.00e-05	2	156	2	22194342
Pubmed	Cooperative oncogenic effect and cell signaling crosstalk of co‑occurring HER2 and mutant PIK3CA in mammary epithelial cells.	ERBB2 PIK3CA	2.00e-05	2	156	2	28902361
Pubmed	Association between gain-of-function mutations in PIK3CA and resistance to HER2-targeted agents in HER2-amplified breast cancer cell lines.	ERBB2 PIK3CA	2.00e-05	2	156	2	19633047
Pubmed	Regulation of NKCC2 activity by SPAK truncated isoforms.	STK39 OXSR1	2.00e-05	2	156	2	24173353
Pubmed	The Isl1-Lhx3 Complex Promotes Motor Neuron Specification by Activating Transcriptional Pathways that Enhance Its Own Expression and Formation.	LHX3 ISL1	2.00e-05	2	156	2	28451636
Pubmed	Phosphatidylinositol 3-kinase mediates activation of ATM by high NaCl and by ionizing radiation: Role in osmoprotective transcriptional regulation.	PIK3CA ATM	2.00e-05	2	156	2	16728507
Pubmed	Mutant PIK3CA accelerates HER2-driven transgenic mammary tumors and induces resistance to combinations of anti-HER2 therapies.	ERBB2 PIK3CA	2.00e-05	2	156	2	23940356
Pubmed	[Role of phosphatidylinositol 3-kinase and myosin light chain kinase during the activation of thrombin receptors].	MYLK PIK3CA	2.00e-05	2	156	2	19549383
Pubmed	FSIP1 binds HER2 directly to regulate breast cancer growth and invasiveness.	ERBB2 FSIP1	2.00e-05	2	156	2	28674022
Pubmed	Calcium-binding protein 39 facilitates molecular interaction between Ste20p proline alanine-rich kinase and oxidative stress response 1 monomers.	STK39 OXSR1	2.00e-05	2	156	2	23034389
Pubmed	Interaction between HER2 and ATM predicts poor survival in bladder cancer patients.	ERBB2 ATM	2.00e-05	2	156	2	36056635
Pubmed	Functional link between BLM defective in Bloom's syndrome and the ataxia-telangiectasia-mutated protein, ATM.	BLM ATM	2.00e-05	2	156	2	12034743
Pubmed	Autophosphorylation at serine 1981 stabilizes ATM at DNA damage sites.	MDC1 ATM	2.00e-05	2	156	2	20026654
Pubmed	The Ste20 kinases SPAK and OSR1 travel between cells through exosomes.	STK39 OXSR1	2.00e-05	2	156	2	27122160
Pubmed	ATM suppresses SATB1-induced malignant progression in breast epithelial cells.	SATB1 ATM	2.00e-05	2	156	2	23251624
Pubmed	SPAK and OSR1 Sensitive Cell Membrane Protein Abundance and Activity of KCNQ1/E1 K+ Channels.	STK39 OXSR1	2.00e-05	2	156	2	26584301
Pubmed	Outcome impact of PIK3CA mutations in HER2-positive breast cancer patients treated with trastuzumab.	ERBB2 PIK3CA	2.00e-05	2	156	2	23612454
Pubmed	Physiological expression of PI3K H1047R mutation reveals its anti-metastatic potential in ErbB2-driven breast cancer.	ERBB2 PIK3CA	2.00e-05	2	156	2	35538223
Pubmed	Oncogenic PIK3CA gene mutations and HER2/neu gene amplifications determine the sensitivity of uterine serous carcinoma cell lines to GDC-0980, a selective inhibitor of Class I PI3 kinase and mTOR kinase (TORC1/2).	ERBB2 PIK3CA	2.00e-05	2	156	2	23891627
Pubmed	Expression of SATB1 and HER2 in breast cancer and the correlations with clinicopathologic characteristics.	ERBB2 SATB1	2.00e-05	2	156	2	25956130
Pubmed	Dual HER2/PIK3CA Targeting Overcomes Single-Agent Acquired Resistance in HER2-Amplified Uterine Serous Carcinoma Cell Lines In Vitro and In Vivo.	ERBB2 PIK3CA	2.00e-05	2	156	2	26333383
Pubmed	PIK3CA Mutation in the ShortHER Randomized Adjuvant Trial for Patients with Early HER2+ Breast Cancer: Association with Prognosis and Integration with PAM50 Subtype.	ERBB2 PIK3CA	2.00e-05	2	156	2	32843527
Pubmed	Role of the WNK-activated SPAK kinase in regulating blood pressure.	STK39 OXSR1	2.00e-05	2	156	2	20091762
Pubmed	Dysregulation of the DNA Damage Response and KMT2A Rearrangement in Fetal Liver Hematopoietic Cells.	KMT2A ATM	2.00e-05	2	156	2	26657054
Pubmed	Fulvestrant plus palbociclib versus fulvestrant plus placebo for treatment of hormone-receptor-positive, HER2-negative metastatic breast cancer that progressed on previous endocrine therapy (PALOMA-3): final analysis of the multicentre, double-blind, phase 3 randomised controlled trial.	ERBB2 PIK3CA	2.00e-05	2	156	2	26947331
Pubmed	SPAK and OSR1 Sensitive Kir2.1 K+ Channels.	STK39 OXSR1	2.00e-05	2	156	2	26673921
Pubmed	Frequent detection of PIK3CA mutations in single circulating tumor cells of patients suffering from HER2-negative metastatic breast cancer.	ERBB2 PIK3CA	2.00e-05	2	156	2	27491860
Pubmed	CD49f protein expression varies among genetic subgroups of B lymphoblastic leukemia and is distinctly low in KMT2A-rearranged cases.	ITGA6 KMT2A	2.00e-05	2	156	2	31894899
Pubmed	ERBB2-Mutated Metastatic Non-Small Cell Lung Cancer: Response and Resistance to Targeted Therapies.	ERBB2 PIK3CA	2.00e-05	2	156	2	28167203
Pubmed	Proteomic Analysis of the EWS-Fli-1 Interactome Reveals the Role of the Lysosome in EWS-Fli-1 Turnover.	IL16 TCF20 RSF1 RNF114 GMNN CLIC1 SMARCC1 KMT2A KIF2A HDGFL2	2.40e-05	425	156	10	24999758
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	RALGAPA1 RPL28 IL16 MAP6 TNC CAPZB PSD3 DNM1L OPA3 SRCIN1 OPCML SLC4A10 NAV1 TJP2 KMT2A PPP1R9B KIF2A ENO2 GOT2	2.42e-05	1431	156	19	37142655
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	TCF20 AHCTF1 DLGAP5 RSF1 DDX42 CCNK BLM SART1 ANLN RBM19 MDC1 SMARCC1 KMT2A CCDC86 HDGFL2	2.78e-05	954	156	15	36373674
Pubmed	Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.	RPL28 FBLL1 AHCTF1 DDX42 IFI16 CCNK RALY SART1 CLPTM1L MDC1 TJP2 KMT2A CCDC86 ZC3HAV1	3.04e-05	847	156	14	35850772
Pubmed	The functional interactome of PYHIN immune regulators reveals IFIX is a sensor of viral DNA.	TCF20 RSF1 IFI16 HIRA SATB1 RBM19 MDC1 CCDC86 ZC3HAV1	3.05e-05	349	156	9	25665578
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	TCF20 MAP6 DLGAP5 ADGRB3 DNM1L HIRA SART1 NAV1 SMARCC1 PPP1R9B PRKCI DIXDC1 KIF2A WDFY3 FRMPD3	3.10e-05	963	156	15	28671696
Pubmed	Unbiased Identification of trans Regulators of ADAR and A-to-I RNA Editing.	RPL28 AHCTF1 BLM ANLN MDC1 SMARCC1 ATP1A4 SLC25A31	3.29e-05	271	156	8	32433965
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	TCF20 TNC DHX40 DLGAP5 RSF1 USP24 CLPTM1L DNAH12 SMARCC1 CHD6 WDFY3 SOAT1	3.35e-05	638	156	12	31182584
Pubmed	DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity.	TCF20 DDX42 IFI16 HIRA BLM ANLN MDC1 SMARCC1 KIF2A ATM	4.11e-05	453	156	10	29656893
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	ERBB2 IL16 SPAM1 FBLL1 DCDC1 AHCTF1 RSF1 ELL3 MTPAP RALY SART1 PJA2 TRABD SMARCC1 STK39 WDFY3	4.51e-05	1116	156	16	31753913
Pubmed	ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents.	DDX42 CAPZB RALY SART1 CLIC1 ANLN MDC1 PPP1R9B KIF2A CCDC86 HDGFL2 ZC3HAV1	4.64e-05	660	156	12	32780723
Pubmed	Structures of the Human SPAK and OSR1 Conserved C-Terminal (CCT) Domains.	STK39 OXSR1	5.98e-05	3	156	2	34726826
Pubmed	Two-stage candidate gene study of chromosome 3p demonstrates an association between nonsynonymous variants in the MST1R gene and Crohn's disease.	TRAIP NOD2	5.98e-05	3	156	2	18200509
Pubmed	Stromal Tumor-infiltrating Lymphocytes in NRG Oncology/NSABP B-31 Adjuvant Trial for Early-Stage HER2-Positive Breast Cancer.	ERBB2 PIK3CA	5.98e-05	3	156	2	30888406
Pubmed	The PARP3- and ATM-dependent phosphorylation of APLF facilitates DNA double-strand break repair.	PARP3 ATM	5.98e-05	3	156	2	23449221
Pubmed	SPAK and OSR1 play essential roles in potassium homeostasis through actions on the distal convoluted tubule.	STK39 OXSR1	5.98e-05	3	156	2	27068441
Pubmed	PIK3CA mutations, PTEN, and pHER2 expression and impact on outcome in HER2-positive early-stage breast cancer patients treated with adjuvant chemotherapy and trastuzumab.	ERBB2 PIK3CA	5.98e-05	3	156	2	22172323
Pubmed	Antibody targeting of HER2/HER3 signaling overcomes heregulin-induced resistance to PI3K inhibition in prostate cancer.	ERBB2 PIK3CA	5.98e-05	3	156	2	25471734
Pubmed	Regulation of ClC-2 activity by SPAK and OSR1.	STK39 OXSR1	5.98e-05	3	156	2	25323061
Pubmed	Targeting the kinase activities of ATR and ATM exhibits antitumoral activity in mouse models of MLL-rearranged AML.	KMT2A ATM	5.98e-05	3	156	2	27625305
Pubmed	Targeted disruption of mouse EGF receptor: effect of genetic background on mutant phenotype.	ERBB2 ITGA6	5.98e-05	3	156	2	7618084
Pubmed	UFL1 promotes histone H4 ufmylation and ATM activation.	UFC1 ATM	5.98e-05	3	156	2	30886146
Pubmed	USP37 regulates DNA damage response through stabilizing and deubiquitinating BLM.	BLM ATM	5.98e-05	3	156	2	34606619
Pubmed	Unlike Its Paralog LEDGF/p75, HRP-2 Is Dispensable for MLL-R Leukemogenesis but Important for Leukemic Cell Survival.	KMT2A HDGFL2	5.98e-05	3	156	2	33477970
Pubmed	Genomic and Transcriptomic Landscape of Triple-Negative Breast Cancers: Subtypes and Treatment Strategies.	ERBB2 PIK3CA	5.98e-05	3	156	2	30853353
Pubmed	WNK1 regulates phosphorylation of cation-chloride-coupled cotransporters via the STE20-related kinases, SPAK and OSR1.	STK39 OXSR1	5.98e-05	3	156	2	16263722
Pubmed	Orchestration of the DNA-damage response by the RNF8 ubiquitin ligase.	MDC1 ATM	5.98e-05	3	156	2	18006705
Pubmed	OSR1 and SPAK cooperatively modulate Sertoli cell support of mouse spermatogenesis.	STK39 OXSR1	5.98e-05	3	156	2	27853306
Pubmed	Negative regulation of the creatine transporter SLC6A8 by SPAK and OSR1.	STK39 OXSR1	5.98e-05	3	156	2	25531585
Interaction	H3C3 interactions	TCF20 AHCTF1 DLGAP5 RSF1 HIRA BLM FSIP2 SATB1 ANLN MDC1 SMARCC1 KMT2A CHD6 CCDC86 HDGFL2	6.75e-06	495	155	15	int:H3C3
Interaction	YWHAZ interactions	RALGAPA1 TICRR ERBB2 MAP6 RSF1 MAP3K20 CAPZB PSD3 DNM1L IFI16 RALY FSIP2 ANLN STARD9 TBC1D1 MDC1 NFX1 NAV1 TJP2 KMT2A PPP1R9B PRKCI KIF2A ATM WDFY3 SOAT1	8.48e-06	1319	155	26	int:YWHAZ
Interaction	BANF2 interactions	APAF1 DDIT4L STK39 OXSR1	2.21e-05	22	155	4	int:BANF2
Interaction	ASF1A interactions	CASP8AP2 TCF20 CAPZB HIRA BLM ANLN MDC1 SMARCC1 KMT2A CHD6	2.37e-05	249	155	10	int:ASF1A
Interaction	ADARB1 interactions	RPL28 TCF20 AHCTF1 RALY BLM PNPT1 ANLN RBM19 MDC1 SMARCC1 ATP1A4 CCDC86 SLC25A31 ZC3HAV1	2.60e-05	489	155	14	int:ADARB1
Interaction	YWHAH interactions	RALGAPA1 TICRR TCF20 MAP3K20 CAPZB PSD3 DNM1L KIAA0753 PJA2 PIK3CA ANLN STARD9 TBC1D1 NAV1 TJP2 KMT2A PPP1R9B PRKCI KIF2A BICC1 DOP1A ZC3HAV1	3.77e-05	1102	155	22	int:YWHAH
Interaction	CIT interactions	RPL28 FBLL1 TCF20 AHCTF1 RSF1 DDX42 CAPZB IFI16 RALY SART1 CLPTM1L DNAH12 ANLN ELFN1 RBM19 MDC1 SLC4A10 TJP2 SMARCC1 KMT2A KIF2A OXSR1 CCDC86 HDGFL2 SLC25A31 ZC3HAV1	4.34e-05	1450	155	26	int:CIT
Cytoband	3q26.3	PIK3CA PRKCI	1.15e-04	5	157	2	3q26.3
GeneFamily	Chloride intracellular channels	CLIC5 CLIC1	3.96e-04	6	94	2	307
GeneFamily	PDZ domain containing	IL16 TJP2 PPP1R9B FRMPD3 PDZD2	1.18e-03	152	94	5	1220
GeneFamily	Fibronectin type III domain containing	MYLK TNC FNDC1 ELFN1 USH2A	1.49e-03	160	94	5	555
GeneFamily	LIM class homeoboxes	LHX3 ISL1	1.71e-03	12	94	2	522
GeneFamily	Kinesins\|Pleckstrin homology domain containing	STARD9 KIF2A KIF13A	1.76e-03	46	94	3	622
GeneFamily	StAR related lipid transfer domain containing	ACOT12 STARD9	2.69e-03	15	94	2	759
GeneFamily	Ring finger proteins	VPS11 TRAIP RNF114 UBOX5 PJA2 RNF139	3.12e-03	275	94	6	58
GeneFamily	Zinc fingers\|Zinc fingers PARP-type\|Poly(ADP-ribose) polymerases	PARP3 ZC3HAV1	3.46e-03	17	94	2	684
Coexpression	NAKAYA_PLASMACYTOID_DENDRITIC_CELL_FLUMIST_AGE_18_50YO_7DY_UP	RALGAPA1 UBR2 VPS11 APPBP2 ISCA1 DDX42 APAF1 CAPZB CPD ELL3 PJA2 PIK3CA TBC1D1 NFX1 SMARCC1 KMT2A PRKCI OXSR1 ATM EMC2 RNF139 CCDC86 S100PBP	9.03e-07	1215	156	23	M41122
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	UBR2 APPBP2 AHCTF1 DLGAP5 DDX42 USP24 PSD3 ITGA6 HIRA BLM PJA2 TJP2 PRKCI STK39 KIF2A OXSR1 WDFY3 EMC2	3.69e-06	856	156	18	M4500
Coexpression	GSE10239_KLRG1INT_VS_KLRG1HIGH_EFF_CD8_TCELL_DN	DLGAP5 APAF1 ITGA6 ATP10D TMEM98 ANLN SLC4A10 KMT2A	2.66e-05	199	156	8	M3070
Coexpression	GSE17301_IFNA2_VS_IFNA2_AND_ACD3_ACD28_STIM_CD8_TCELL_UP	RALGAPA1 APPBP2 TCF20 CPD EXT2 SOAT1 DOP1A ZC3HAV1	2.76e-05	200	156	8	M8042
Coexpression	GSE12003_MIR223_KO_VS_WT_BM_PROGENITOR_4D_CULTURE_UP	FSIP1 NT5C3A RGL3 USP24 SATB1 NFX1 KMT2A SOAT1	2.76e-05	200	156	8	M387
Coexpression	GSE17721_PAM3CSK4_VS_GADIQUIMOD_24H_BMDC_DN	UBR2 DHX40 NT5C3A APAF1 USP24 RNF114 CBX6 SOCS4	2.76e-05	200	156	8	M3981
Coexpression	LAKE_ADULT_KIDNEY_C20_COLLECTING_DUCT_INTERCALATED_CELLS_TYPE_A_CORTEX	RALGAPA1 PSD3 ITGA6 TBC1D1 SHOC1 ADGRF5 CLNK	3.63e-05	152	156	7	M39239
ToppCell	E18.5-samps-Epithelial-Alveolar_epithelial-AT1\|E18.5-samps / Age Group, Lineage, Cell class and subclass	MAP6 TKTL2 NOD2 DNAH12 CLIC5 ATP1A4 NAIF1	4.06e-07	130	157	7	eb16a8f8f62add5fdd29c78d4608b6d1a06767f1
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PSD3 ITGA6 TBC1D1 SHOC1 ADGRF5 STK39 CLNK	1.45e-06	157	157	7	c17c5c01fcb65c453690c265ec4f300ecdfefd34
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Hematologic-red_blood_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ISCA1 NT5C3A TRAIP BOLA3 CLIC5 TMCC2 TDRD12	2.02e-06	165	157	7	62dd54dfbec7f43a41546a1fec719545c2608a36
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PSD3 ITGA6 TBC1D1 SHOC1 ADGRF5 CLNK PDZD2	3.09e-06	176	157	7	25ebc8716aa44e44fce577701e3e82c6745a75ab
ToppCell	Control_saline-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast\|Control_saline / Treatment groups by lineage, cell group, cell type	MYLK TNC MAP3K20 FNDC1 CBX6 DIXDC1 ATP1A4	7.16e-06	200	157	7	c5e051f1aac8dda376c342a9932785a23450e073
ToppCell	NS-critical-d_07-13-Lymphoid-NKT-proliferating\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	TICRR TRAIP DLGAP5 GMNN BLM AUNIP ANLN	7.16e-06	200	157	7	7f5cd05bb1b9a83baceddb7d7f0a9ec9781cda29
ToppCell	mild-CD8+_T_naive\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ANKRD31 ITGA6 SATB1 KMT2A KIF2A ATM ZC3HAV1	7.16e-06	200	157	7	c825320599a61a4c629d736f5c0fd6f1f405540a
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Connecting_Tubule_Intercalated_Cell_Type_A\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PSD3 ITGA6 TBC1D1 SHOC1 ADGRF5 CLNK	1.55e-05	150	157	6	87968ce885a4959616f0321f58517fe8029ba1b1
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PSD3 ITGA6 TBC1D1 SHOC1 ADGRF5 CLNK	3.04e-05	169	157	6	2a21f2cef959526bfe3c8f081f4f7e9dd4e01a37
ToppCell	droplet-Marrow-nan-3m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FSIP1 PARP3 DNM1L NOD2 SOCS4 NAV1	3.04e-05	169	157	6	5f5bec13208f4c3b6eacbba180c8a6402743b76e
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PSD3 ITGA6 TBC1D1 SHOC1 ADGRF5 CLNK	3.46e-05	173	157	6	0bc2aacae60c6d3276b0949eb0748b4ac1f56e54
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PSD3 ITGA6 TBC1D1 SHOC1 ADGRF5 CLNK	3.58e-05	174	157	6	5f4436863a40f8bca46e2989bca66c02b6be88d4
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PSD3 ITGA6 TBC1D1 SHOC1 ADGRF5 CLNK	3.69e-05	175	157	6	77c16e615c0fb9c83f29d7e0a547be72635fac81
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PSD3 ITGA6 TBC1D1 SHOC1 ADGRF5 CLNK	3.69e-05	175	157	6	1d8da48236549c01381f777ce5b2937f9f86acc2
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PSD3 ITGA6 TBC1D1 SHOC1 ADGRF5 CLNK	3.69e-05	175	157	6	98947a226b5a2ac7091ff9d34243ea7736add973
ToppCell	390C-Lymphocytic-NK_cells-Proliferating_NK_cell\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	TICRR TRAIP DLGAP5 GMNN AUNIP DNAH12	3.81e-05	176	157	6	8813c01ea080f373fe3970c5e1ba4c2dca0f7f02
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PSD3 ITGA6 TBC1D1 SHOC1 ADGRF5 CLNK	3.81e-05	176	157	6	c2c4306476989bc2fb30dab00250ef7915842f13
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PSD3 ITGA6 TBC1D1 SHOC1 ADGRF5 CLNK	3.93e-05	177	157	6	8e4005fad50e6f919da175f3b9ae58849dbd60b1
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PSD3 ITGA6 TBC1D1 SHOC1 ADGRF5 CLNK	4.19e-05	179	157	6	e6ae070b4c52ba08167c7d64ea4cfbac0454c1bf
ToppCell	390C-Lymphocytic-NK_cells-Proliferating_NK_cell\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	TICRR TRAIP DLGAP5 GMNN AUNIP DNAH12	4.19e-05	179	157	6	e67ad7ab04d0c1309296f57c1f53c5ca14c213fe
ToppCell	3'-GW_trimst-2-LargeIntestine-Epithelial-epithelial_progenitor_cell-TA\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TRAIP DLGAP5 NXPE1 MYO5C ANLN FRMPD3	4.32e-05	180	157	6	271ee52ed8f21f78ddf68e52fc88fe582701675e
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PSD3 ITGA6 TBC1D1 SHOC1 ADGRF5 CLNK	4.46e-05	181	157	6	30729f0364f719c044712a51453e22dc2c1a232b
ToppCell	facs-Heart-LV-3m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYLK DDIT4L OPCML PIK3CA TBC1D1 PDZD2	4.46e-05	181	157	6	1db1eb7d330a7e5090994007ae287e11f0a74450
ToppCell	facs-Heart-LV-3m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYLK DDIT4L OPCML PIK3CA TBC1D1 PDZD2	4.46e-05	181	157	6	06174ce9240c9261c0f51a1b0d875335d60722e5
ToppCell	Mesenchymal_cells-Adipo-CAR\|Mesenchymal_cells / Lineage and Cell class	MYLK TNC DDIT4L ADGRF5 SRPX SOAT1	4.46e-05	181	157	6	1cfb03eb03a37b036b4eeacec69c9b8163af1ee4
ToppCell	TCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-5\|TCGA-Liver / Sample_Type by Project: Shred V9	TICRR DLGAP5 BLM AUNIP ANLN S100PBP	4.74e-05	183	157	6	f604a8b62c7088fad8365dbf8d910fc980bd3ba8
ToppCell	COVID-19-kidney-CD-IC-A\|kidney / Disease (COVID-19 only), tissue and cell type	PSD3 ITGA6 TBC1D1 SHOC1 ADGRF5 CLNK	4.74e-05	183	157	6	5c7597a5b2bf6a481ca2c7e68560179214150fa0
ToppCell	LPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MYLK TNC MAP3K20 FNDC1 DIXDC1 BICC1	5.03e-05	185	157	6	e64e8c98dd88d91f6501d3fb10b60fd2f3c90af3
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Degenerative_Cortical_Intercalated_Cell_Type_A\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PSD3 ITGA6 TBC1D1 SHOC1 ADGRF5 CLNK	5.03e-05	185	157	6	9438097e94219c1db922b8507e3a29106d32a923
ToppCell	facs-Skin-Telogen-3m-Epithelial-actively_dividing_stem_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TICRR FSIP1 TRAIP DLGAP5 AUNIP ANLN	5.19e-05	186	157	6	9feef5936985e936b3d88f9d1bb012abb6468570
ToppCell	facs-Skin-Telogen-3m-Epithelial-keratinocyte_stem_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TICRR FSIP1 TRAIP DLGAP5 AUNIP ANLN	5.19e-05	186	157	6	89f5b06bc56674af304912d481ac697c7c870904
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TICRR TNC TRAIP DLGAP5 BLM ANLN	5.34e-05	187	157	6	e41e39fd3791acf8ae5376cc5061e196d96868ae
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TICRR TNC TRAIP DLGAP5 BLM ANLN	5.34e-05	187	157	6	cefa211ef224e803ea9467882e2ca74d0b1492f1
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PSD3 ITGA6 TBC1D1 SHOC1 ADGRF5 CLNK	5.34e-05	187	157	6	7b0168bdaa7c6c6b39878aff6a17f0943189a380
ToppCell	Multiple_Sclerosis-Lymphocyte-T_NK-T_NK_proliferative\|Multiple_Sclerosis / Disease, Lineage and Cell Type	TICRR TRAIP DLGAP5 GMNN AUNIP ANLN	5.50e-05	188	157	6	6c05797a5d0635d89ffcf4aca52178687129ccb4
ToppCell	ASK454-Endothelial-Lymphatic\|Endothelial / Donor, Lineage and Cell class of Lung cells from Dropseq	OPA3 TMEM98 FUNDC2 SMARCC1 KIF2A HDGFL2	5.67e-05	189	157	6	316c857dec9383823e09f966bca62d52d933b141
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TICRR DLGAP5 BLM ANLN STARD9 NAV1	5.83e-05	190	157	6	31de1727822e9818652946dfb962daee77ffad68
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PSD3 ITGA6 TBC1D1 SHOC1 ADGRF5 CLNK	5.83e-05	190	157	6	b3bccf4dd95e986db3cee324a6737f5fcc22e8e5
ToppCell	PND10\|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYLK TNC CPD NAV1 TJP2 ADGRF5	5.83e-05	190	157	6	d67e2814047c8df2ae4b7bc8be9539f5df6ecef2
ToppCell	facs-Marrow-KLS-18m-Hematologic-hematopoietic_stem_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ITGA6 EXT2 TMEM98 CBX6 SMARCC1 SORD	5.83e-05	190	157	6	11f32f46661e44770782b8ec13c00028e1dfc3cd
ToppCell	facs-Marrow-KLS-18m-Hematologic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ITGA6 EXT2 TMEM98 CBX6 SMARCC1 SORD	5.83e-05	190	157	6	20f4f6fe09345878484086047061d6f900f9d476
ToppCell	droplet-Lung-LUNG-30m-Lymphocytic-Proliferating_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TICRR TRAIP DLGAP5 GMNN AUNIP STK39	6.01e-05	191	157	6	239300ff76f2c855b2b04d3002461158be90a01b
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	RGL3 MYO5C CLIC5 PRKCI ADGRF5 PDZD2	6.01e-05	191	157	6	ca5669bd6f4a17471acae3eb229f845cc2e08efa
ToppCell	ILEUM-inflamed-(1)_T_cell-(1)_Th17_Trm\|(1)_T_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	NT5C3A CAPZB CPD BLM CLIC1 SLC4A10	6.18e-05	192	157	6	12f7ea575da5d650c740e6060f5dab0478e563dd
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	RGL3 PSD3 ITGA6 ADGRF5 STK39 CLNK	6.18e-05	192	157	6	f7e7491426bbd6ed29a465b58bf67acb93dbb90a
ToppCell	moderate-Epithelial-FOXN4+\|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	DLGAP5 MYO5C SPATA33 ANLN FAM227A ATP12A	6.55e-05	194	157	6	5dffa578149104dda33774361e9e77b227b5f1ce
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_cycling\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	TICRR TRAIP DLGAP5 GMNN BLM ANLN	6.74e-05	195	157	6	926eb3fc5d028be936885bea0654a77db3107234
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PSD3 ITGA6 TBC1D1 SHOC1 ADGRF5 CLNK	6.74e-05	195	157	6	f7d9adadd37209ce1a38e5d621607b9c9270fed8
ToppCell	Bronchial-10x5prime-Epithelial-Epi_airway_basal-Dividing_Basal\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	TICRR TRAIP DLGAP5 AUNIP ANLN ATP12A	7.13e-05	197	157	6	25bbe270d0897b9b1bd00d205f66efd1def81b99
ToppCell	COVID-19_Moderate-T/NK_proliferative\|World / disease group, cell group and cell class	TICRR TRAIP DLGAP5 GMNN BLM ANLN	7.33e-05	198	157	6	bf0131fbca6032e1aab4aa807f8c1d3be689cb7f
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Ductal_Carcinoma\|TCGA-Breast / Sample_Type by Project: Shred V9	TICRR COPG1 DLGAP5 BLM AUNIP ANLN	7.33e-05	198	157	6	880f9817f5145f10f29fc05c5866090433532fe2
ToppCell	cycling_basal_cell\|World / shred by cell class for turbinate	TICRR TRAIP DLGAP5 GMNN AUNIP ANLN	7.33e-05	198	157	6	e86c1224f5b0890a50a25257628e90c790aae7cd
ToppCell	LPS_anti-TNF-Hematopoietic_Erythro-Megakary-Erythro-Mega-Erythroid\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	ISCA1 NT5C3A PKD1L1 DLGAP5 TMCC2 ZC3HAV1	7.53e-05	199	157	6	565404c155dfac57c020a8f2d09cbf756da20ffd
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	MYLK TNC MAP3K20 FNDC1 DIXDC1 ATP1A4	7.53e-05	199	157	6	e9820d5fb4e8b46973c4c50ac5db8fb4a1bf603b
ToppCell	(02)_MMP9/10+-(2)_GFP_FOXI1\|(02)_MMP9/10+ / shred by cell type by condition	MYLK NT5C3A RSF1 IFI16 PJA2 PRKCI	7.53e-05	199	157	6	18a7f9ced4364f45b184bd529f32ef02c27779d3
ToppCell	mild-CD4+_T_naive\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ITGA6 SATB1 KMT2A KIF2A ATM ZC3HAV1	7.53e-05	199	157	6	3e4baaf4ee23f257d821194468102c00a8ad2f21
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TRO USP24 OPCML NAV1 KIF13A PDZD2	7.53e-05	199	157	6	19a97e27a4758e794ce7246d295e112b47931a48
ToppCell	Control_saline-Mesenchymal_myocytic-Myofibroblastic\|Control_saline / Treatment groups by lineage, cell group, cell type	MYLK TNC MAP3K20 FNDC1 DIXDC1 ATP1A4	7.75e-05	200	157	6	9d5b3c2dcfa55d50acc2ce2c319d51aa525d4cd1
ToppCell	LPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	MYLK TNC MAP3K20 FNDC1 DIXDC1 ATP1A4	7.75e-05	200	157	6	87827041663013f5e7273168dc8709d69840e7ce
ToppCell	NS-critical-LOC-Lymphoid-Treg\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	TICRR TRAIP DLGAP5 GMNN AUNIP ANLN	7.75e-05	200	157	6	d51e5c8c154b073caaf0cc09a3a3c0aafd57e44b
ToppCell	Control_saline-Mesenchymal_myocytic\|Control_saline / Treatment groups by lineage, cell group, cell type	MYLK TNC MAP3K20 FNDC1 DIXDC1 ATP1A4	7.75e-05	200	157	6	5ed4261157cd51109b314818133ac3a0d34ee5fa
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	MYLK TNC MAP3K20 FNDC1 DIXDC1 ATP1A4	7.75e-05	200	157	6	c596a53c0b63c9deaac7d99fcbdd94ecfa96b86c
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW23-Stem_cells-Neuroepithelial_cell\|GW23 / Sample Type, Dataset, Time_group, and Cell type.	TRAIP DLGAP5 GMNN MYO5C BLM ANLN	7.75e-05	200	157	6	c9c832f489629b8724501ddfede984b41a7b674d
ToppCell	MS-Multiple_Sclerosis-Lymphocyte-T/NK-T/NK_proliferative\|Multiple_Sclerosis / Disease, condition lineage and cell class	TICRR TRAIP DLGAP5 GMNN AUNIP ANLN	7.75e-05	200	157	6	7faf1e37364203a08d2b2544979e848b41e36b1c
ToppCell	distal-Hematologic-Proliferating_Macrophage-3\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	TICRR TRAIP DLGAP5 GMNN AUNIP ANLN	7.75e-05	200	157	6	9c03a8da12d29618f72c429836c1d1bd84a78b12
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	MYLK TNC MAP3K20 FNDC1 DIXDC1 ATP1A4	7.75e-05	200	157	6	08bf8c00eee6468215edb3611296bfc8784c4d56
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW12-Macroglial-Astrocyte\|GW12 / Sample Type, Dataset, Time_group, and Cell type.	TNC AHCTF1 USP24 ITGA6 BICC1 PDZD2	7.75e-05	200	157	6	b9bd6c4381c92bfc1bfff9aa778a62a41d08f1ef
ToppCell	Kidney\|World / Skin and Kidney Cells in Lupus Nephritis Patients.	MYLK RGL3 CASR TBC1D1 ADGRF5 BICC1	7.75e-05	200	157	6	1f99afa1f3c32a2a9cfb4ad33ff4d404e34fac63
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	MYLK TNC MAP3K20 FNDC1 DIXDC1 ATP1A4	7.75e-05	200	157	6	dcdaec3ca3a3024dc1b8788c417003f84c2bffdc
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW23-Stem_cells\|GW23 / Sample Type, Dataset, Time_group, and Cell type.	TRAIP DLGAP5 GMNN MYO5C BLM ANLN	7.75e-05	200	157	6	d7832ab1ed0ff0a6f7e3ac11b2095dc72c90af44
ToppCell	distal-3-Hematologic-Proliferating_Macrophage\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	TICRR TRAIP DLGAP5 GMNN AUNIP ANLN	7.75e-05	200	157	6	1b65c97e8123d0572d31525d6a10bc7f16857959
ToppCell	healthy_donor-Lymphocytic-T_cell-CD4+_T_cell_(ISG_high)\|healthy_donor / Disease condition, Lineage, Cell class and subclass	ANKRD31 RTN4IP1 DOK4 ANLN DIXDC1	1.29e-04	138	157	5	97f5dc17522462133e582b508ad0ef036e656872
ToppCell	390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6\|390C / Donor, Lineage, Cell class and subclass (all cells)	HIRA NOD2 RPP38-DT ATM FRMPD3	1.53e-04	143	157	5	d877d914e4e74db2053baa310d318d6440e672bc
ToppCell	normal_Lung-T/NK_cells-Naive_CD8+_T\|T/NK_cells / Location, Cell class and cell subclass	ANKRD31 RPL28 IL16 EMC2 CCDC86	1.91e-04	150	157	5	b81f8dfc7755252c457e38bb32b103af3b6f1c01
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_104\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DDIT4L BOLA3 SPATA33 ANLN ATP12A	1.97e-04	151	157	5	ea62e92ccb984f44559b434f35c1c4450767c8f1
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PSD3 ITGA6 SHOC1 ADGRF5 CLNK	2.03e-04	152	157	5	9391b46a441cf031665df1d142e3f65e98675eeb
ToppCell	droplet-Liver-LIVER-NPC-1m-Lymphocytic-B_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL16 ISCA1 BLM CLIC5 TMPRSS7	2.10e-04	153	157	5	a8f83ec640fae51d4fba34b92e3d6cca4999e930
ToppCell	Enthrocyte\|World / shred on cell class and cell subclass (v4)	ISCA1 NT5C3A TRAIP BOLA3 TMCC2	2.10e-04	153	157	5	654265f3c14344071b2af7ca05cbdbb17ce2c5d3
ToppCell	Enthrocyte\|World / shred on cell class and cell subclass (v4)	ISCA1 NT5C3A TRAIP BOLA3 TMCC2	2.10e-04	153	157	5	105b91f5277d145f7717307d7eb9b7d8e8e23576
ToppCell	10x5'-bone_marrow-Lymphocytic_B-Pro-B\|bone_marrow / Manually curated celltypes from each tissue	MYLK PSD3 MYO5C DOK4 NAV1	2.16e-04	154	157	5	8a8c3851888ab86ca2b13ccc042cde1fef8d88f8
ToppCell	10x5'-Liver-Lymphocytic_T_CD4/8-lo-Trm_Tgd\|Liver / Manually curated celltypes from each tissue	OPA3 RTN4IP1 ACOT12 CLNK PDZD2	2.16e-04	154	157	5	c6308074468235c88ef4ea43ab155d9f86cbf261
ToppCell	356C-Lymphocytic-ILC-ILC-2\|356C / Donor, Lineage, Cell class and subclass (all cells)	GCNA SRCIN1 CLIC5 CLNK HEATR5B	2.23e-04	155	157	5	0fd66c623cb433ceaa893bc21ba2e3b394faaf70
ToppCell	TCGA-Kidney-Primary_Tumor-Renal_Cell_Carcinoma-Kidney_Clear_Cell_Renal_Carcinoma-6\|TCGA-Kidney / Sample_Type by Project: Shred V9	TICRR DLGAP5 BLM AUNIP ANLN	2.29e-04	156	157	5	d249747c7108a0edfc72d24c09b0b0e4ed662b40
ToppCell	3'_v3-bone_marrow-Lymphocytic_B-Pro-B\|bone_marrow / Manually curated celltypes from each tissue	MYLK TRO PSD3 MYO5C DOK4	2.29e-04	156	157	5	b093dbba6662e4fffc8aa577587b77f64ac44b56
ToppCell	saliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage-macrophage,_alveolar-Macro_c1-C1QC\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	EXT2 GMNN AUNIP ANLN TTI1	2.29e-04	156	157	5	abea3c183d32062b009a79a2bdf861021989c7ef
ToppCell	mild_COVID-19_(asymptomatic)-CD4+_T_naive\|World / disease group, cell group and cell class (v2)	ANKRD31 ITGA6 SATB1 ATM RBM43	2.36e-04	157	157	5	23879e65a6acc33d9aad096cd23604a77b0ac9c2
ToppCell	NS-moderate-d_07-13-Epithelial-FOXN4+\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DLGAP5 DNAH12 ANLN FAM227A DIXDC1	2.36e-04	157	157	5	410c9d74a2085179cfb39853cb6d330fa98c9c1b
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SPAM1 PSD3 ITGA6 ADGRF5 CLNK	2.58e-04	160	157	5	174a4ab27114efcc63be36929b80680be3c35c9b
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PSD3 ITGA6 SHOC1 ADGRF5 CLNK	2.58e-04	160	157	5	1e210e526ea4d84fc58a798a26c0929bcb69fd89
ToppCell	lymphoid-B_cell-pro-B\|World / Lineage, cell class and subclass	TICRR MYLK DDIT4L PSD3 SRPX	2.65e-04	161	157	5	23138e579f07d5a6f20d41457cb573b4ac95a4ef
ToppCell	390C-Myeloid-Dendritic-cDC_proliferating_2\|Dendritic / Donor, Lineage, Cell class and subclass (all cells)	TRAIP DLGAP5 ANLN TMCC2 DIXDC1	2.73e-04	162	157	5	a957c7e347189b72fbd47db3075bb5e879a21c67
ToppCell	droplet-Marrow-nan-18m-Lymphocytic-immature_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ISCA1 NT5C3A SRCIN1 BOLA3 TMCC2	2.73e-04	162	157	5	08ee7ae56e4927874515c47adc86dd845bf29a26
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell_prolif\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CASP8AP2 MAP6 BLM PIK3CA ENO2	2.81e-04	163	157	5	1feb4ef7b8abcfca9a72c8d13c40548de79e7db2
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Connecting_Tubule_Intercalated_Cell_Type_A\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	RGL3 PSD3 SHOC1 ADGRF5 CLNK	2.97e-04	165	157	5	9bd332e5ede759a00a47728ea5558c215efdd77a
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TICRR TRAIP DLGAP5 BLM ANLN	3.14e-04	167	157	5	50c29ea660bf07b890e4ac1a1985d0761d863dee
ToppCell	facs-Trachea-24m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l15\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MAP6 TNC PARP3 BICC1 SLC25A31	3.14e-04	167	157	5	55c3c68af269fcf40f2b080ae4489523609ad388
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Connecting_Tubule_Intercalated_Cell_Type_A\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PSD3 ITGA6 SHOC1 ADGRF5 CLNK	3.14e-04	167	157	5	edc5f04584b44f99ff9a62bbe0dab6fc044fb334
ToppCell	droplet-Lung-nan-3m-Lymphocytic-Regulatory_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OPCML NXPE3 CHD6 ENO2 S100PBP	3.23e-04	168	157	5	1df3c8c7a6dceb901805eaba7f86f9943f4f1a9d
ToppCell	droplet-Lung-nan-3m-Lymphocytic-regulatory_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OPCML NXPE3 CHD6 ENO2 S100PBP	3.23e-04	168	157	5	1586451d437b70b2dffe41d782b694702dcaf50b
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PSD3 ITGA6 SHOC1 ADGRF5 CLNK	3.32e-04	169	157	5	4b3a7b4a497178799b6b2f0b744f5fb752cee31a
Disease	Ovarian neoplasm	ERBB2 OPCML PIK3CA	4.90e-06	7	155	3	cv:C0919267
Disease	Adenocarcinoma of lung (disorder)	ERBB2 CLPTM1L SATB1 PIK3CA EIF2B5 SMARCC1 STK39 ATM	1.41e-05	206	155	8	C0152013
Disease	Microcephaly	UFC1 TRAIP DNM1L KIF2A GOT2	2.78e-05	67	155	5	C0025958
Disease	telomere length	PSD3 CASR MYNN ELFN1 ATM ATP1A4 CLNK TMPRSS7 SOAT1	4.40e-05	313	155	9	EFO_0004505
Disease	cutaneous melanoma	MYNN RALY CLPTM1L SPATA33 TMCC2 ATM	4.46e-05	121	155	6	EFO_0000389
Disease	Optic Atrophy 1	DNM1L OPA3	8.20e-05	3	155	2	C0338508
Disease	Benign neoplasm of stomach	ERBB2 PIK3CA ATM	9.16e-05	17	155	3	C0153943
Disease	Neoplasm of uncertain or unknown behavior of stomach	ERBB2 PIK3CA ATM	9.16e-05	17	155	3	C0496905
Disease	Carcinoma in situ of stomach	ERBB2 PIK3CA ATM	9.16e-05	17	155	3	C0154060
Disease	Glioma	ERBB2 MYLK PSD3 PIK3CA ATM	9.79e-05	87	155	5	C0017638
Disease	Bladder Neoplasm	ISL1 CLPTM1L KMT2A CHD6 ATM ENO2	1.00e-04	140	155	6	C0005695
Disease	Malignant neoplasm of urinary bladder	ISL1 CLPTM1L KMT2A CHD6 ATM ENO2	1.04e-04	141	155	6	C0005684
Disease	urinary bladder carcinoma	PSD3 MYNN CLPTM1L CBX6	1.10e-04	47	155	4	MONDO_0004986
Disease	Stomach Carcinoma	ERBB2 PIK3CA ATM	1.76e-04	21	155	3	C0699791
Disease	ovarian cancer (is_implicated_in)	ERBB2 OPCML NOD2 PIK3CA	2.18e-04	56	155	4	DOID:2394 (is_implicated_in)
Disease	spermatogenic failure (is_implicated_in)	GCNA IQCN SHOC1	2.33e-04	23	155	3	DOID:0111910 (is_implicated_in)
Disease	Neoplasm of the genitourinary tract	ERBB2 OPCML PIK3CA	2.65e-04	24	155	3	cv:C0042065
Disease	Liver carcinoma	TICRR TRAIP DLGAP5 GMNN PNPT1 PIK3CA ANLN KMT2A SRPX ATM	3.66e-04	507	155	10	C2239176
Disease	Pigmented Basal Cell Carcinoma	ERBB2 CLPTM1L PIK3CA	4.23e-04	28	155	3	C1368275
Disease	Neoplasm of uncertain or unknown behavior of ovary	ERBB2 OPCML PIK3CA	4.70e-04	29	155	3	C0496920
Disease	Carcinoma, Basal Cell	ERBB2 CLPTM1L PIK3CA	4.70e-04	29	155	3	C4721806
Disease	Ovarian Carcinoma	ERBB2 OPCML PIK3CA	5.20e-04	30	155	3	C0029925
Disease	familial hemiplegic migraine (implicated_via_orthology)	ATP12A ATP1A4	5.66e-04	7	155	2	DOID:0060178 (implicated_via_orthology)
Disease	chronic mucus hypersecretion	SATB1 USH2A	5.66e-04	7	155	2	EFO_0005673
Disease	suberic acid measurement	PSD3 PDZD2	5.66e-04	7	155	2	EFO_0010534
Disease	Severe Congenital Microcephaly	TRAIP DNM1L KIF2A	5.74e-04	31	155	3	C3853041
Disease	alcohol use disorder (implicated_via_orthology)	ERBB2 PSD3 CLIC5 CLIC1 SMARCC1 ATP1A4	5.96e-04	195	155	6	DOID:1574 (implicated_via_orthology)
Disease	Microlissencephaly	TRAIP DNM1L KIF2A	6.91e-04	33	155	3	C1956147
Disease	Lymphoid leukemia	CLPTM1L KMT2A	7.52e-04	8	155	2	C0023448
Disease	Schizophrenia	MAP6 PSD3 OPCML PIK3CA NAV1 KMT2A PPP1R9B DIXDC1 KIF2A OXSR1 ATM CCDC86 ENO2	8.14e-04	883	155	13	C0036341
Disease	glycosyl-N-palmitoyl-sphingosine (d18:1/16:0) measurement	ATP10D STK39	9.63e-04	9	155	2	EFO_0800476
Disease	PITUITARY DWARFISM I	TRAIP GMNN	9.63e-04	9	155	2	C0342573
Disease	Conventional (Clear Cell) Renal Cell Carcinoma	ERBB2 APAF1 PIK3CA ATM RNF139	1.13e-03	148	155	5	C0279702
Disease	Head and Neck Carcinoma	ERBB2 PIK3CA	1.20e-03	10	155	2	C3887461
Disease	Carcinoma, Transitional Cell	APAF1 KMT2A CHD6	1.31e-03	41	155	3	C0007138
Disease	nevus count, cutaneous melanoma	RALY CLPTM1L TMCC2 ATM	1.37e-03	91	155	4	EFO_0000389, EFO_0004632
Disease	Gastric cancer	ERBB2 PIK3CA	1.46e-03	11	155	2	cv:C0024623
Disease	Neoplasm of stomach	ERBB2 PIK3CA	1.46e-03	11	155	2	cv:C0038356
Disease	GASTRIC CANCER	ERBB2 PIK3CA	1.46e-03	11	155	2	613659
Disease	nervous system disease (implicated_via_orthology)	ATP12A ATP1A4	1.75e-03	12	155	2	DOID:863 (implicated_via_orthology)
Disease	DEAFNESS, AUTOSOMAL RECESSIVE (disorder)	PNPT1 CLIC5	2.06e-03	13	155	2	C1846647
Disease	Malformations of Cortical Development	PIK3CA KIF2A	2.39e-03	14	155	2	C1955869
Disease	Neoplasm of lung	ERBB2 PIK3CA	2.39e-03	14	155	2	cv:C0024121
Disease	actinic keratosis	RALY SPATA33	2.39e-03	14	155	2	EFO_0002496
Disease	Lung cancer	ERBB2 PIK3CA	2.39e-03	14	155	2	cv:C0242379
Disease	LUNG CANCER	ERBB2 PIK3CA	2.39e-03	14	155	2	211980
Disease	Cortical Dysplasia	PIK3CA KIF2A	2.39e-03	14	155	2	C0431380
Disease	susceptibility to rubella infection measurement	OPCML KIF13A PDZD2	2.60e-03	52	155	3	EFO_0008418
Disease	urate measurement	DCDC1 FSIP1 TRAIP PSD3 SART1 NAV1 CLNK HEATR5B NAIF1 BICC1 SORD TDRD12	2.80e-03	895	155	12	EFO_0004531
Disease	leukemia	BLM KMT2A ATM	3.05e-03	55	155	3	C0023418
Disease	migraine disorder, fasting blood insulin measurement	ADGRB3 OPCML	3.13e-03	16	155	2	EFO_0004466, MONDO_0005277
Disease	Hypermetropia, Myopia	PNPT1 TMEM98 RBM19 BICC1 SORD	3.29e-03	189	155	5	HP_0000540, HP_0000545
Disease	Carcinoma, Granular Cell	ERBB2 PIK3CA SMARCC1 KMT2A	3.33e-03	116	155	4	C0205644
Disease	Adenocarcinoma, Tubular	ERBB2 PIK3CA SMARCC1 KMT2A	3.33e-03	116	155	4	C0205645
Disease	Adenocarcinoma, Oxyphilic	ERBB2 PIK3CA SMARCC1 KMT2A	3.33e-03	116	155	4	C0205642
Disease	Carcinoma, Cribriform	ERBB2 PIK3CA SMARCC1 KMT2A	3.33e-03	116	155	4	C0205643
Disease	Adenocarcinoma, Basal Cell	ERBB2 PIK3CA SMARCC1 KMT2A	3.33e-03	116	155	4	C0205641
Disease	Adenocarcinoma	ERBB2 PIK3CA SMARCC1 KMT2A	3.33e-03	116	155	4	C0001418
Disease	gout	PSD3 CLIC5 SMARCC1 ATP1A4 CLNK	3.84e-03	196	155	5	EFO_0004274
Disease	alpha synuclein measurement	PNPT1 OXSR1	3.97e-03	18	155	2	EFO_0009323
Disease	Chronic myeloproliferative disorder	TRAIP GMNN	4.42e-03	19	155	2	C1292778
Disease	Malignant Neoplasms	ERBB2 BLM PIK3CA ATM	4.72e-03	128	155	4	C0006826
Disease	Sarcomatoid Renal Cell Carcinoma	ERBB2 APAF1 PIK3CA RNF139	4.72e-03	128	155	4	C1266043
Disease	Chromophobe Renal Cell Carcinoma	ERBB2 APAF1 PIK3CA RNF139	4.72e-03	128	155	4	C1266042
Disease	Collecting Duct Carcinoma of the Kidney	ERBB2 APAF1 PIK3CA RNF139	4.72e-03	128	155	4	C1266044
Disease	Papillary Renal Cell Carcinoma	ERBB2 APAF1 PIK3CA RNF139	4.72e-03	128	155	4	C1306837
Disease	Renal Cell Carcinoma	ERBB2 APAF1 PIK3CA RNF139	4.72e-03	128	155	4	C0007134
Disease	leprosy, Crohn's disease	NOD2 LACC1	4.90e-03	20	155	2	EFO_0000384, EFO_0001054
Disease	cerebellum white matter volume change measurement, age at assessment	ADGRB3 TJP2	4.90e-03	20	155	2	EFO_0008007, EFO_0021498
Disease	breast carcinoma (is_marker_for)	MDC1 ATM ENO2	5.11e-03	66	155	3	DOID:3459 (is_marker_for)

Protein segments in the cluster

Peptide	Gene	Start	Entry
QKSSVRIKNPTRVEE	NT5C3A	56	Q9H0P0
QRPVVFVTRKKLVNA	APAF1	121	O14727
KNVLIVRREKTTSTP	FAM227A	446	F5H4B4
VKIPVAIKVLRENTS	ERBB2	746	P04626
TQAEARPLIKVKQLT	ELFN1	311	P0C7U0
KRLDKKRSVPVATVE	ELL3	211	Q9HB65
AEVVQVIRNPAKLKR	CCDC86	316	Q9H6F5
SPFSETVRIINRKVK	CBX6	151	O95503
LIVRKNIQDSVPKAV	DNM1L	656	O00429
TIKSQRPRSVHEKRV	ADGRB3	261	O60242
KFRNTPIVKATNREL	CASR	636	P41180
ERKVRVKSPRTQVGS	DIXDC1	561	Q155Q3
VTQILKEKFPRATAI	BOLA3	36	Q53S33
RQVKRAVVVSPKEEN	CCNK	331	O75909
EKQRVAIARTILKAP	ABCB6	731	Q9NP58
RVGQVITIKAKVTRA	ACOT12	66	Q8WYK0
SKVLVPEKLTQRIAQ	DDIT4L	76	Q96D03
ERRQNKTTTRTKVIP	DOP1A	1836	Q5JWR5
PVKVVVDVLRQASKA	APPBP2	241	Q92624
VLQISKESPQEIARK	SORD	221	Q00796
KAAVPLIRSQKIDVA	CLIP4	366	Q8N3C7
PSKSVIVKSVERNAL	BICC1	391	Q9H694
ARKQVTSASLEKVRP	CBLL2	141	Q8N7E2
IRNEKRVPTEHLQKT	CASP8AP2	486	Q9UKL3
SSVDQPLKIARDKVV	CAPZB	41	P47756
VVFNVTTVDLKRKPA	CLIC5	206	Q9NZA1
TVTNPKRIERAVEEK	ENO2	321	P09104
ATPLQKSEVVKLVRS	ATP10D	1031	Q9P241
RRVKTNVPVKLFARS	RALY	156	Q9UKM9
AAERSKTVILVKNLP	RBM19	581	Q9Y4C8
NVKESKAPERTVVVA	RBM43	6	Q6ZSC3
RPDDVFIAVKTTRKN	RFNG	56	Q9Y644
TKRVSARTNKARAPE	IQCN	281	Q9H0B3
VKVDRGPVRTVTKRV	PARP3	166	Q9Y6F1
KAAISQLRSPRVKES	OXSR1	351	O95747
VKNSTVAIKSRPVSR	KIAA1107	266	Q9UPP5
AIVNEKIPAVRSKRH	ANKRD31	1286	Q8N7Z5
STRNVIKVPLQKRAV	C22orf46	66	C9J442
ESKINFPIATKRIAV	DCDC1	1641	M0R2J8
VRATVRAVSKRKLQP	ISCA1	6	Q9BUE6
EKQIRIPRSLSVKAA	PRKCI	476	P41743
RANLQRQVKPKTVSE	MYLK	926	Q15746
LRRTKLNQESTAPKV	MDC1	1881	Q14676
KPTTADNKVIDRRRI	MAP6	346	Q96JE9
KTEVRRKVAQVRAAV	NAIF1	76	Q69YI7
RPSIKQVIVRKEDVT	ANLN	686	Q9NQW6
PQQALVIRDSEKKTI	ATP12A	181	P54707
RSPQREEVKTRSLKQ	FSIP2	1741	Q5CZC0
KKDIPVLVATDVAAR	DDX42	546	Q86XP3
NAEVKERVTLKPRSV	EIF2B5	416	Q13144
DLVNVAKKRTNIIPV	FBLL1	211	A6NHQ2
IRQVSKPLANRIKEA	OPA3	16	Q9H6K4
NQEERPRKTLVSKAI	PDZD2	1016	O15018
QRTFSVPVKQEVKRS	FAM214A	991	Q32MH5
PVTIVIRRKSLQSKE	IL16	1311	Q14005
AVPVTNRIVDNKSKI	DNAH12	2301	Q6ZR08
PAQDIVHTVTVKRKR	MYNN	246	Q9NPC7
EPKRNVVVTAIRGKS	NFX1	1051	Q12986
SKRRDPKVVVQENLR	LACC1	216	Q8IV20
TAKRPRTTITAKQLE	LHX3	156	Q9UBR4
KTITVTPNRIDLRQK	ITGA6	511	P23229
VKNVPSERIATQKIL	MTPAP	271	Q9NVV4
SQDKAPSVVRRALQK	RGL3	636	Q3MIN7
DKLNPRRAKVIIAVS	GPR45	141	Q9Y5Y3
QAKPVKVERTRKRSE	HDGFL2	441	Q7Z4V5
VPEQVIAEAIRKKTR	PIK3CA	216	P42336
NDVAAPDVRKVKITV	OPCML	206	Q14982
IVKNRRTVASIKNDP	KIF2A	91	O00139
EVARRSRITKNVPKQ	ATM	2576	Q13315
AAVSKTAVAPIERVK	SLC25A31	31	Q9H0C2
VVEKLKAVERNRPAS	HEATR5B	1931	Q9P2D3
NVSVAKTPVLRNKDV	BLM	51	P54132
LFPVVSRVTRVCKKD	CYP3A43	366	Q9HB55
ESLVIDRPRVRKQTK	CHD6	1041	Q8TD26
KLRSNPVKVRFSEQV	FRMPD3	146	Q5JV73
TVTEKEVPNKPLRVR	FNDC1	151	Q4ZHG4
KKNPAVTQLVDRTRI	CPD	1016	O75976
IPSSVRITRSKAKDQ	DLGAP5	146	Q15398
PVKVIHRDLKSRNVV	MAP3K20	126	Q9NYL2
KTVAKCQVTPRRNVL	IFI16	186	Q16666
KRNIELAKESRNPVV	FSIP1	256	Q8NA03
TKEDKTVVRQSPRRI	KMT2A	341	Q03164
ELQAPRKRTVKVTLT	KMT2A	2511	Q03164
RNAVIVAKSPASAKR	PRPSAP2	181	O60256
RRAPKRQASSVVVID	GCNA	66	Q96QF7
RVREAIRVSKIPDAK	SPAM1	281	P38567
ITAVKQPEKVAATRQ	COPG1	596	Q9Y678
EVKVSSVTKRTPRRI	AHCTF1	1861	Q8WYP5
EDPTNTAARKRKIAI	EMC2	116	Q15006
TPTAVERLKEQNLVK	HIRA	586	P54198
PRKVAAISVAQRVAE	DHX40	106	Q8IX18
ISRPTAKVAEIRDQK	RSF1	781	Q96T23
RSVLEKNLIKVTVAP	S100PBP	136	Q96BU1
RVQKKIVANRLTSPS	PKD1L1	586	Q8TDX9
LPKETKRQAVAIIFT	DOK4	71	Q8TEW6
LERKVSAKENRQAPV	AUNIP	231	Q9H7T9
LRSPATKVIIKTENI	NXPE1	466	Q8N323
TVAPRRKAVAREKVT	OVGP1	561	Q12889
RKAVAREKVTVPSRN	OVGP1	566	Q12889
EIKENIKNSSVPRRT	GMNN	11	O75496
VSEPAIQVRRKGKST	KIF13A	726	Q9H1H9
ASETTPKELRIKRQN	NAV1	1166	Q8NEY1
NRRTAVKKINSLPEI	RNF139	521	Q8WU17
LKIRKSNQIPTEVRS	FUNDC2	146	Q9BWH2
RSKVVQKPSVRRIST	RTN4IP1	21	Q8WWV3
LSKAVRARTKEDVPQ	USH2A	3486	O75445
SIVLPSQKRKIEQAE	UBOX5	356	O94941
VRENVPRVLNSAKEK	SOAT1	271	P35610
VVSKPREFASLIRNK	TMCC2	421	O75069
LDRSPKTVVVIRTAN	NXPE3	471	Q969Y0
VTQSAAIVPVRTKKR	MRPL45	26	Q9BRJ2
IPVKSKNIRVVVESF	TDRD12	101	Q587J7
ENISKNVDVRPKTSR	SOCS4	6	Q8WXH5
KRVSVVPRFINSQKR	SHOC1	1251	Q5VXU9
VAVRVRPLSKRETKE	STARD9	6	Q9P2P6
SAPVEEVRRVVSKKV	STARD9	2726	Q9P2P6
EVRRVVSKKVVAALP	STARD9	2731	Q9P2P6
KQPEKTTRVRTVLNE	ISL1	176	P61371
RITKTVDRKDPAVNI	KIAA0753	831	Q2KHM9
SVKERIAEPNKLTVR	SRPX	186	P78539
VVETVQVPLSKRAKF	PNPT1	606	Q8TCS8
VVVIKRRSGQRKPAT	RPL28	61	P46779
RKPVSFRQRISTKNE	SMARCC1	291	Q92922
NRQKTRPRTKISVEA	SATB1	641	Q01826
VLPSVRKAEAQIAAK	GOT2	76	P00505
ALRQKRAVATKSPTA	ADGRF5	46	Q8IZF2
TAEEVAARLKIPISK	ATP1A4	646	Q13733
NTQTRLERVDKPISK	CLNK	126	Q7Z7G1
FERTVNVSVPKKTRN	CLPTM1L	86	Q96KA5
VDTKRRTETVQKLCP	CLIC1	46	O00299
TRNPIAEVLARKKRT	COL5A1-AS1	11	Q5SY13
PEKRKAVRVALSSAT	RPP38-DT	36	Q8N326
TAVLRVKRKRSAEPA	SLC7A6OS	6	Q96CW6
KKVVVPQIIITRASN	SPATA33	81	Q96N06
TRRVVSEIPVLKTNA	UFC1	6	Q9Y3C8
VAAIVVKRPRKVQVA	TJP2	111	Q9UDY2
VKRPRKVQVAALQAS	TJP2	116	Q9UDY2
PVKDTVQEVTKVRRN	TICRR	901	Q7Z2Z1
TRIRQEIQELKASPK	VPS11	801	Q9H270
QSEIKRLKISSPVRV	WDFY3	3491	Q8IZQ1
PGTEKARSIVRQKTV	RALGAPA1	741	Q6GYQ0
LKNARKVVTSRPAAV	NOD2	416	Q9HC29
LEVQKPQVKLRRAVS	SRCIN1	1046	Q9C0H9
VKATIKDASLQPRNV	RNF114	121	Q9Y508
RQIEASVVAIRPKKS	TRO	286	Q12816
SVQVVSAQKKLPVRR	TMPRSS7	21	Q7RTY8
DSKRDVVKTIREVQP	TRABD	86	Q9H4I3
AKPDVKTVQVLRDTA	TKTL2	6	Q9H0I9
QKKLTNRIPIVRSFA	SLC4A10	226	Q6U841
SRQSTRKEPVTKQVR	TBC1D1	51	Q86TI0
RVPLKVVRTAENKLS	EXT2	506	Q93063
RVFAILENKKSIPVS	TNC	691	P24821
KLEAIVQKITSPNIR	TCF20	1351	Q9UGU0
LETTVQKVARVKAPN	SART1	651	O43290
PKKSRVSVVRQEAED	USP24	2051	Q9UPU5
IASKTQKDVIRRPTF	ZC3HAV1	671	Q7Z2W4
LTRTPDIAQRAKKVR	STK39	351	Q9UEW8
VIVRNTSRQTKPLKV	UBR2	286	Q8IWV8
EQVVRPKVRKLISSS	PJA2	311	O43164
PITAKVKRNVSERKD	PSD3	1021	Q9NYI0
SVKQPVKLQEAARSV	TTI1	1016	O43156
VAKRISPRVDDVVKS	TMEM98	131	Q9Y2Y6
VKQRVRVKTVPSLFQ	TRAIP	446	Q9BWF2
KRVTPSFVRKVQALL	MYO5C	1681	Q9NQX4
VPQVNSKLVSKRSRV	PPP1R9B	236	Q96SB3