Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	extracellularly ATP-gated monoatomic cation channel activity	P2RX3 P2RX7	1.44e-04	7	53	2	GO:0004931
GeneOntologyMolecularFunction	ATP-gated ion channel activity	P2RX3 P2RX7	2.46e-04	9	53	2	GO:0035381
GeneOntologyMolecularFunction	histone H4K8 acetyltransferase activity	BRPF3 BRPF1	3.74e-04	11	53	2	GO:0043996
GeneOntologyMolecularFunction	histone H4K5 acetyltransferase activity	BRPF3 BRPF1	3.74e-04	11	53	2	GO:0043995
GeneOntologyMolecularFunction	histone H4K12 acetyltransferase activity	BRPF3 BRPF1	4.49e-04	12	53	2	GO:0043997
GeneOntologyMolecularFunction	insulin-like growth factor binding	IGF2R CCN2	1.15e-03	19	53	2	GO:0005520
GeneOntologyMolecularFunction	ubiquitin-like ligase-substrate adaptor activity	PRAMEF7 PRAMEF8 SMAD7	1.35e-03	82	53	3	GO:1990756
GeneOntologyMolecularFunction	nucleotide receptor activity	P2RX3 P2RX7	1.54e-03	22	53	2	GO:0016502
GeneOntologyMolecularFunction	purinergic nucleotide receptor activity	P2RX3 P2RX7	1.54e-03	22	53	2	GO:0001614
GeneOntologyMolecularFunction	histone H4 acetyltransferase activity	BRPF3 BRPF1	1.69e-03	23	53	2	GO:0010485
GeneOntologyMolecularFunction	sialic acid binding	SELE SIGLEC10	1.99e-03	25	53	2	GO:0033691
GeneOntologyMolecularFunction	enzyme-substrate adaptor activity	PRAMEF7 PRAMEF8 SMAD7	2.06e-03	95	53	3	GO:0140767
GeneOntologyMolecularFunction	scavenger receptor activity	ACKR3 DMBT1	2.33e-03	27	53	2	GO:0005044
GeneOntologyCellularComponent	MOZ/MORF histone acetyltransferase complex	BRPF3 BRPF1	1.36e-04	7	54	2	GO:0070776
GeneOntologyCellularComponent	H3 histone acetyltransferase complex	BRPF3 BRPF1	1.82e-04	8	54	2	GO:0070775
MousePheno	limbs/digits/tail phenotype	PRAMEF7 IGF2R P2RX7 ADAMTS9 DNAJC16 INPP5E EPHA2 WNT10A LIPT2 CCN2 LRRK1 RFT1 CMYA5 PRAMEF8	1.85e-05	1258	44	14	MP:0005371
Domain	TSP_1	RSPO3 ADAMTSL1 ADAMTS9 CCN2 SSPOP	1.03e-06	63	54	5	PF00090
Domain	TSP1	RSPO3 ADAMTSL1 ADAMTS9 CCN2 SSPOP	1.21e-06	65	54	5	SM00209
Domain	TSP1_rpt	RSPO3 ADAMTSL1 ADAMTS9 CCN2 SSPOP	1.21e-06	65	54	5	IPR000884
Domain	TSP1	RSPO3 ADAMTSL1 ADAMTS9 CCN2 SSPOP	1.21e-06	65	54	5	PS50092
Domain	CTCK_1	VWF CCN2 SSPOP	1.81e-05	18	54	3	PS01185
Domain	Cys_knot_C	VWF CCN2 SSPOP	5.02e-05	25	54	3	IPR006207
Domain	CTCK_2	VWF CCN2 SSPOP	5.02e-05	25	54	3	PS01225
Domain	VWFC_1	VWF CCN2 SSPOP	1.52e-04	36	54	3	PS01208
Domain	P2X_receptor	P2RX3 P2RX7	1.71e-04	7	54	2	PF00864
Domain	P2X_purnocptor	P2RX3 P2RX7	1.71e-04	7	54	2	IPR001429
Domain	-	P2RX3 P2RX7	1.71e-04	7	54	2	2.60.490.10
Domain	P2X_RECEPTOR	P2RX3 P2RX7	1.71e-04	7	54	2	PS01212
Domain	P2X_extracellular_dom	P2RX3 P2RX7	1.71e-04	7	54	2	IPR027309
Domain	VWC	VWF CCN2 SSPOP	1.79e-04	38	54	3	SM00214
Domain	VWFC_2	VWF CCN2 SSPOP	1.79e-04	38	54	3	PS50184
Domain	EPL1	BRPF3 BRPF1	2.27e-04	8	54	2	PF10513
Domain	Enhancer_polycomb-like_N	BRPF3 BRPF1	2.27e-04	8	54	2	IPR019542
Domain	VWF_dom	VWF CCN2 SSPOP	2.42e-04	42	54	3	IPR001007
Domain	TIL	VWF SSPOP	5.32e-04	12	54	2	PF01826
Domain	C8	VWF SSPOP	5.32e-04	12	54	2	PF08742
Domain	Unchr_dom_Cys-rich	VWF SSPOP	6.27e-04	13	54	2	IPR014853
Domain	C8	VWF SSPOP	6.27e-04	13	54	2	SM00832
Domain	TIL_dom	VWF SSPOP	7.30e-04	14	54	2	IPR002919
Domain	Znf_FYVE_PHD	BRPF3 PHF24 BRPF1 ZFYVE26	8.58e-04	147	54	4	IPR011011
Domain	Zinc_finger_PHD-type_CS	BRPF3 PHF24 BRPF1	8.79e-04	65	54	3	IPR019786
Domain	VWD	VWF SSPOP	9.59e-04	16	54	2	SM00216
Domain	VWF_type-D	VWF SSPOP	9.59e-04	16	54	2	IPR001846
Domain	VWFD	VWF SSPOP	9.59e-04	16	54	2	PS51233
Domain	VWD	VWF SSPOP	9.59e-04	16	54	2	PF00094
Domain	VWC_out	VWF SSPOP	1.36e-03	19	54	2	SM00215
Domain	PRAME_family	PRAMEF7 PRAMEF8	1.36e-03	19	54	2	IPR026271
Domain	PWWP	BRPF3 BRPF1	1.51e-03	20	54	2	SM00293
Domain	EPHD	BRPF3 BRPF1	1.83e-03	22	54	2	PS51805
Domain	CT	VWF CCN2	1.83e-03	22	54	2	SM00041
Domain	PWWP	BRPF3 BRPF1	2.00e-03	23	54	2	PF00855
Domain	PWWP_dom	BRPF3 BRPF1	2.00e-03	23	54	2	IPR000313
Domain	PWWP	BRPF3 BRPF1	2.17e-03	24	54	2	PS50812
Domain	Peptidase_M12B_ADAM-TS	ADAMTSL1 ADAMTS9	2.17e-03	24	54	2	IPR013273
Domain	Znf_PHD	BRPF3 PHF24 BRPF1	2.32e-03	91	54	3	IPR001965
Domain	Bromodomain_CS	BRPF3 BRPF1	2.55e-03	26	54	2	IPR018359
Domain	ZF_PHD_2	BRPF3 PHF24 BRPF1	2.62e-03	95	54	3	PS50016
Domain	ZF_PHD_1	BRPF3 PHF24 BRPF1	2.70e-03	96	54	3	PS01359
Domain	VWC	VWF CCN2	2.96e-03	28	54	2	PF00093
Domain	BROMODOMAIN_1	BRPF3 BRPF1	5.12e-03	37	54	2	PS00633
Domain	Bromodomain	BRPF3 BRPF1	5.40e-03	38	54	2	PF00439
Domain	BROMODOMAIN_2	BRPF3 BRPF1	6.26e-03	41	54	2	PS50014
Domain	BROMO	BRPF3 BRPF1	6.56e-03	42	54	2	SM00297
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	ZNF462 VWF MYOM1 ADAMTS9 AGL CD164 CCN2 CMYA5	9.61e-07	497	54	8	23414517
Pubmed	Potential Involvement of P2 Receptors in the Pathological Processes of Hyperthyroidism: A Pilot Study.	P2RX3 P2RX7	2.37e-06	2	54	2	27312548
Pubmed	Tumour cells down-regulate CCN2 gene expression in co-cultured fibroblasts in a Smad7- and ERK-dependent manner.	CCN2 SMAD7	2.37e-06	2	54	2	24090133
Pubmed	Endothelial activation markers soluble E-selectin and von Willebrand factor in primary hyperparathyroidism.	SELE VWF	2.37e-06	2	54	2	21471547
Pubmed	Impaired flow mediated dilatation as evidence of endothelial dysfunction in chronic atrial fibrillation: relationship to plasma von Willebrand factor and soluble E-selectin levels.	SELE VWF	2.37e-06	2	54	2	17996280
Pubmed	The ectoenzyme E-NPP3 negatively regulates ATP-dependent chronic allergic responses by basophils and mast cells.	P2RX7 ENPP3	2.37e-06	2	54	2	25692702
Pubmed	O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation.	ADAMTSL1 ADAMTS9 CCN2 SSPOP	5.81e-06	75	54	4	20637190
Pubmed	Evidence for up-regulation of purinergic receptor genes associating with TRPV1 receptors and neurotrophic factors in the inflamed human esophagus.	P2RX3 P2RX7	7.09e-06	3	54	2	25336328
Pubmed	E-NPP3 controls plasmacytoid dendritic cell numbers in the small intestine.	P2RX7 ENPP3	7.09e-06	3	54	2	28225814
Pubmed	Endothelial markers are associated with pancreatic necrosis and overall prognosis in acute pancreatitis: A preliminary cohort study.	SELE VWF	7.09e-06	3	54	2	28007459
Pubmed	Co-Expression and Functional Interactions of Death Receptor 3 and E-Selectin in Clear Cell Renal Cell Carcinoma.	SELE TNFRSF25	7.09e-06	3	54	2	35063404
Pubmed	Smad7 blocks transforming growth factor-β1-induced gingival fibroblast-myofibroblast transition via inhibitory regulation of Smad2 and connective tissue growth factor.	CCN2 SMAD7	7.09e-06	3	54	2	21054221
Pubmed	Localization of P2X receptor subtypes 2, 3 and 7 in human urinary bladder.	P2RX3 P2RX7	7.09e-06	3	54	2	26253104
Pubmed	Endothelial cell markers in patients with pseudoexfoliation syndrome.	SELE VWF	7.09e-06	3	54	2	22593709
Pubmed	Fast Ca2+ Transients of Inner Hair Cells Arise Coupled and Uncoupled to Ca2+ Waves of Inner Supporting Cells in the Developing Mouse Cochlea.	P2RX3 P2RX7	1.42e-05	4	54	2	30104958
Pubmed	The Chromatin Regulator BRPF3 Preferentially Activates the HBO1 Acetyltransferase but Is Dispensable for Mouse Development and Survival.	BRPF3 BRPF1	1.42e-05	4	54	2	26677226
Pubmed	Profibrogenic transforming growth factor-beta/activin receptor-like kinase 5 signaling via connective tissue growth factor expression in hepatocytes.	CCN2 SMAD7	2.36e-05	5	54	2	17657819
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	TNFRSF25 VWF KLHL7 ADAMTS9 USP9X ZNF197 RAPGEF4 CCN2 MED13L CMYA5	2.49e-05	1285	54	10	35914814
Pubmed	Molecular physiology of P2X receptors.	P2RX3 P2RX7	3.54e-05	6	54	2	12270951
Pubmed	Increased serum vWF and sVCAM-1 levels are associated with late or very late angiographic stent thrombosis after sirolimus-eluting stent implantation.	SELE VWF	3.54e-05	6	54	2	20508517
Pubmed	The DNA sequence and analysis of human chromosome 6.	RSPO3 BRPF3 IGF2R CMTR1 ENPP3 CD164 CCN2	4.84e-05	622	54	7	14574404
Pubmed	Update of P2X receptor properties and their pharmacology: IUPHAR Review 30.	P2RX3 P2RX7	4.94e-05	7	54	2	33125712
Pubmed	Molecular architecture of quartet MOZ/MORF histone acetyltransferase complexes.	BRPF3 BRPF1	4.94e-05	7	54	2	18794358
Pubmed	Membrane compartments and purinergic signalling: occurrence and function of P2X receptors in lung.	P2RX3 P2RX7	4.94e-05	7	54	2	19076210
Pubmed	ATP-gated P2X cation-channels.	P2RX3 P2RX7	4.94e-05	7	54	2	18657557
Pubmed	Go it alone no more--P2X7 joins the society of heteromeric ATP-gated receptor channels.	P2RX3 P2RX7	4.94e-05	7	54	2	17895406
Pubmed	Down-Regulation of Inpp5e Associated With Abnormal Ciliogenesis During Embryonic Neurodevelopment Under Inositol Deficiency.	INPP5E PKHD1	4.94e-05	7	54	2	34093381
Pubmed	Meta-analysis of new genome-wide association studies of colorectal cancer risk.	MED13L SMAD7	4.94e-05	7	54	2	21761138
Pubmed	The contribution of genetic factors to thrombotic and bleeding outcomes in coronary patients randomised to IIb/IIIa antagonists.	SELE VWF	1.06e-04	10	54	2	12082590
Pubmed	Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.	ADAMTSL1 VWF DMBT1 SSPOP	1.61e-04	175	54	4	28071719
Pubmed	TGF-beta signaling is dynamically regulated during the alveolarization of rodent and human lungs.	CCN2 SMAD7	1.83e-04	13	54	2	18095342
Pubmed	Vascular dimorphism ensured by regulated proteoglycan dynamics favors rapid umbilical artery closure at birth.	ADAMTS9 INPP5E	1.83e-04	13	54	2	32909945
Pubmed	Platr4 is an early embryonic lncRNA that exerts its function downstream on cardiogenic mesodermal lineage commitment.	VWF CCN2	2.13e-04	14	54	2	36347239
Pubmed	Role of LTBP4 in alveolarization, angiogenesis, and fibrosis in lungs.	VWF CCN2	2.45e-04	15	54	2	28684544
Pubmed	White matter integrity as an intermediate phenotype: exploratory genome-wide association analysis in individuals at high risk of bipolar disorder.	ADAMTS9 AGL	2.45e-04	15	54	2	23218918
Pubmed	CXCL12 defines lung endothelial heterogeneity and promotes distal vascular growth.	VWF ACKR3	2.80e-04	16	54	2	36239312
Pubmed	Arx acts as a regional key selector gene in the ventral telencephalon mainly through its transcriptional repression activity.	RSPO3 ACKR3	2.80e-04	16	54	2	19627984
Pubmed	Differential expression of PRAMEL1, a cancer/testis antigen, during spermatogenesis in the mouse.	PRAMEF7 PRAMEF8	3.17e-04	17	54	2	23565261
Pubmed	Mouse Pramel1 regulates spermatogonial development by inhibiting retinoic acid signaling during spermatogenesis.	PRAMEF7 PRAMEF8	3.17e-04	17	54	2	37781892
Pubmed	The promoter of the oocyte-specific gene, Oog1, functions in both male and female meiotic germ cells in transgenic mice.	PRAMEF7 PRAMEF8	3.56e-04	18	54	2	23894331
Pubmed	Oogenesin is a novel mouse protein expressed in oocytes and early cleavage-stage embryos.	PRAMEF7 PRAMEF8	3.56e-04	18	54	2	12890732
Pubmed	Oocyte-specific gene Oog1 suppresses the expression of spermatogenesis-specific genes in oocytes.	PRAMEF7 PRAMEF8	3.56e-04	18	54	2	29731491
Pubmed	Identification of a new expanding family of genes characterized by atypical LRR domains. Localization of a cluster preferentially expressed in oocyte.	PRAMEF7 PRAMEF8	3.56e-04	18	54	2	14675769
Pubmed	Pramel15 facilitates zygotic nuclear DNMT1 degradation and DNA demethylation.	PRAMEF7 PRAMEF8	3.56e-04	18	54	2	39181896
Pubmed	Muscle composition is regulated by a Lox-TGFβ feedback loop.	CCN2 SMAD7	3.98e-04	19	54	2	25715398
Pubmed	Coronary Artery Formation Is Driven by Localized Expression of R-spondin3.	RSPO3 WNT10A	3.98e-04	19	54	2	28834739
Pubmed	Pramel7 mediates ground-state pluripotency through proteasomal-epigenetic combined pathways.	PRAMEF7 PRAMEF8	3.98e-04	19	54	2	28604677
Pubmed	Preferentially Expressed Antigen in Melanoma (PRAME) and the PRAME Family of Leucine-Rich Repeat Proteins.	PRAMEF7 PRAMEF8	4.42e-04	20	54	2	26694250
Pubmed	Oog1, an oocyte-specific protein, interacts with Ras and Ras-signaling proteins during early embryogenesis.	PRAMEF7 PRAMEF8	4.42e-04	20	54	2	16580637
Pubmed	Pramel7 mediates LIF/STAT3-dependent self-renewal in embryonic stem cells.	PRAMEF7 PRAMEF8	4.42e-04	20	54	2	21425410
Pubmed	ARRDC1 and ARRDC3 act as tumor suppressors in renal cell carcinoma by facilitating YAP1 degradation.	USP9X EPHA2	4.88e-04	21	54	2	29416926
Pubmed	KAT7/HBO1/MYST2 Regulates CENP-A Chromatin Assembly by Antagonizing Suv39h1-Mediated Centromere Inactivation.	BRPF3 BRPF1	4.88e-04	21	54	2	27270040
Pubmed	Sertoli cell-only phenotype and scRNA-seq define PRAMEF12 as a factor essential for spermatogenesis in mice.	PRAMEF7 PRAMEF8	5.36e-04	22	54	2	31729367
Pubmed	Co-adaptor driven assembly of a CUL3 E3 ligase complex.	USP9X AGL	5.36e-04	22	54	2	35120648
Pubmed	Oogenesis specific genes (Nobox, Oct4, Bmp15, Gdf9, Oogenesin1 and Oogenesin2) are differentially expressed during natural and gonadotropin-induced mouse follicular development.	PRAMEF7 PRAMEF8	5.86e-04	23	54	2	19480014
Pubmed	Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	ADAMTSL1 SUSD5 SSPOP	5.93e-04	105	54	3	9628581
Pubmed	Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution.	RSPO3 ADAMTS9	6.39e-04	24	54	2	20935629
Pubmed	MAGE-B4, a binding partner of PRAMEF12, is dispensable for spermatogenesis and male fertility in mice.	PRAMEF7 PRAMEF8	6.94e-04	25	54	2	37451217
Pubmed	Genes and microRNAs associated with mouse cleft palate: A systematic review and bioinformatics analysis.	IGF2R ADAMTS9	6.94e-04	25	54	2	29475039
Pubmed	Incomplete reactivation of Oct4-related genes in mouse embryos cloned from somatic nuclei.	PRAMEF7 PRAMEF8	6.94e-04	25	54	2	12620990
Pubmed	Tubby family proteins are adapters for ciliary trafficking of integral membrane proteins.	INPP5E PKHD1	6.94e-04	25	54	2	28154160
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	ZNF462 TPP2 IGF2R P2RX7 KLHL7 USP9X RAPGEF4	6.96e-04	963	54	7	28671696
Pubmed	Expression profiling in transgenic FVB/N embryonic stem cells overexpressing STAT3.	PRAMEF7 PRAMEF8	7.51e-04	26	54	2	18500982
Pubmed	Transcriptome analysis in prenatal IGF1-deficient mice identifies molecular pathways and target genes involved in distal lung differentiation.	IGF2R CCN2	8.10e-04	27	54	2	24391734
Pubmed	Differences in gene expression between mouse and human for dynamically regulated genes in early embryo.	PRAMEF7 PRAMEF8	8.72e-04	28	54	2	25089626
Pubmed	Wnt5a potentiates TGF-β signaling to promote colonic crypt regeneration after tissue injury.	RSPO3 WNT10A	9.35e-04	29	54	2	22956684
Pubmed	Thirteen Ovary-Enriched Genes Are Individually Not Essential for Female Fertility in Mice.	PRAMEF7 PRAMEF8	1.00e-03	30	54	2	38786026
Pubmed	Genetic interactions of the androgen and Wnt/beta-catenin pathways for the masculinization of external genitalia.	RSPO3 WNT10A	1.00e-03	30	54	2	19282366
Pubmed	Atlas of Wnt and R-spondin gene expression in the developing male mouse lower urogenital tract.	RSPO3 WNT10A	1.00e-03	30	54	2	21936019
Pubmed	LSM14B is essential for oocyte meiotic maturation by regulating maternal mRNA storage and clearance.	PRAMEF7 PRAMEF8	1.14e-03	32	54	2	37889087
Pubmed	Retinoic acid receptors are required for skeletal growth, matrix homeostasis and growth plate function in postnatal mouse.	PRAMEF7 PRAMEF8	1.36e-03	35	54	2	19389355
Pubmed	A global genomic transcriptional code associated with CNS-expressed genes.	ZNF462 ACKR3 AGL PKHD1	1.51e-03	318	54	4	16919269
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	IGF2R INPP5E ZFYVE26 LRRK1 MED13L CHRM4 SMAD7	1.54e-03	1105	54	7	35748872
Interaction	ASB15 interactions	USP9X AGL ZFYVE26 ASB15	2.44e-06	37	52	4	int:ASB15
Cytoband	Ensembl 112 genes in cytogenetic band chr1p36	PRAMEF7 TNFRSF25 DNAJC16 EPHA2 PRAMEF8	1.23e-03	681	54	5	chr1p36
Cytoband	1p36.21	PRAMEF7 PRAMEF8	2.53e-03	63	54	2	1p36.21
GeneFamily	Purinergic receptors P2X	P2RX3 P2RX7	1.15e-04	7	43	2	214
GeneFamily	PWWP domain containing	BRPF3 BRPF1	1.24e-03	22	43	2	1147
GeneFamily	PHD finger proteins	BRPF3 PHF24 BRPF1	1.27e-03	90	43	3	88
GeneFamily	PRAME family	PRAMEF7 PRAMEF8	1.48e-03	24	43	2	686
Coexpression	PEDRIOLI_MIR31_TARGETS_DN	SELE VWF MYOM1 P2RX7 ADAMTS9 ACKR3 CD164	2.14e-05	413	54	7	M2494
Coexpression	AIZARANI_LIVER_C29_MVECS_2	SELE RSPO3 VWF ADAMTS9 ACKR3 CCN2	4.41e-05	313	54	6	M39128
Coexpression	NABA_ECM_GLYCOPROTEINS	RSPO3 VWF CCN2 DMBT1 SSPOP	4.62e-05	191	54	5	MM17059
Coexpression	NABA_ECM_GLYCOPROTEINS	RSPO3 VWF CCN2 DMBT1 SSPOP	5.22e-05	196	54	5	M3008
Coexpression	EGFR_UP.V1_DN	ACKR3 AGL DTL RFWD3 SMAD7	5.22e-05	196	54	5	M2633
Coexpression	TRAVAGLINI_LUNG_VEIN_CELL	SELE VWF ADAMTS9	7.74e-05	40	54	3	M41663
ToppCell	Endothelial-A-Donor_04\|World / lung cells shred on cell class, cell subclass, sample id	SELE VWF ADAMTS9 ACKR3 RAPGEF4 CCN2	9.77e-08	185	54	6	ae49c61f6ecf128fe2a958b8c75c83688da75f59
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_vein\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SELE RSPO3 VWF ADAMTS9 RAPGEF4 CCN2	1.04e-07	187	54	6	e35716f8b482be3bf5ab79f087a9caf67a9d197a
ToppCell	Control-Endothelial-VE_Venous\|Control / Disease state, Lineage and Cell class	SELE RSPO3 VWF ADAMTS9 RAPGEF4 CCN2	1.18e-07	191	54	6	617546cf4883dedf3323e03a53ba5adec334cf8e
ToppCell	LPS-antiTNF-Endothelial-Endothelial-Vein\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SELE RSPO3 VWF ADAMTS9 ACKR3 RAPGEF4	1.22e-07	192	54	6	81baf1c4063469bb0c03a8602b40e387ba7b0dfb
ToppCell	LPS-IL1RA-Endothelial-Endothelial-Vein\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SELE RSPO3 VWF ADAMTS9 ACKR3 RAPGEF4	1.22e-07	192	54	6	717f3d3bbee4d0f64ba1341ee2b00a407ba1e0f3
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Endothelial-Vein\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SELE RSPO3 VWF ADAMTS9 ACKR3 RAPGEF4	1.25e-07	193	54	6	7261c1ce30c796b61c6ec58e64a051baa24732ff
ToppCell	5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_systemic-EC_venous_systemic_L.2.2.0.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SELE RSPO3 ADAMTSL1 VWF ADAMTS9 RAPGEF4	1.37e-07	196	54	6	5609b2d93172a488b35d854298a3a4e504e17e28
ToppCell	5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_systemic\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SELE RSPO3 VWF ADAMTS9 RAPGEF4 CCN2	1.46e-07	198	54	6	68ee0baa2f5cf239f2356cc59fee9041a7732bba
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_vein-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SELE VWF ADAMTS9 RP1L1 RAPGEF4	1.76e-06	166	54	5	f7926ee266dcbf10df375cd921f1db5a2fa604f8
ToppCell	COPD-Endothelial-VE_Venous\|World / Disease state, Lineage and Cell class	SELE VWF ADAMTS9 RAPGEF4 CCN2	2.55e-06	179	54	5	9968da1adcb561d9bf167a42ab5d9de85c071c4a
ToppCell	COPD-Endothelial-VE_Venous\|Endothelial / Disease state, Lineage and Cell class	SELE RSPO3 VWF ADAMTS9 CCN2	2.55e-06	179	54	5	e816dd846a6918ec143b57a380c3a47ed073b66e
ToppCell	droplet-Limb_Muscle-Pre-Sort\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SELE VWF MYOM1 ADAMTS9 SUSD5	2.62e-06	180	54	5	af2bafcd1b2082629de3ea336711add01565c4c4
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SELE VWF MYOM1 ADAMTS9 SUSD5	2.62e-06	180	54	5	f29a995cf6e1a1836ed68b73258d9370bf3d4434
ToppCell	Endothelial-A-IPF_02\|World / lung cells shred on cell class, cell subclass, sample id	SELE ADAMTSL1 VWF ADAMTS9 RAPGEF4	2.84e-06	183	54	5	2c3f2c25c38f0598b4787d2ec335efe00fdc9751
ToppCell	Control-Endothelial_cells-Pulmonary_venous_endothelial_cells\|Control / group, cell type (main and fine annotations)	SELE RSPO3 VWF ADAMTS9 RAPGEF4	2.84e-06	183	54	5	46be9f96755c7b65aeac061d95d15abeb6466034
ToppCell	COPD-Endothelial-VE_Venous\|COPD / Disease state, Lineage and Cell class	SELE VWF ADAMTS9 RAPGEF4 CCN2	2.91e-06	184	54	5	44d716e7ba46a1ed03f5992631289653f8fd7d5e
ToppCell	LPS-IL1RA-Endothelial-Endothelial-Activated_Gen_Cap\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SELE VWF ADAMTS9 ACKR3 RAPGEF4	2.99e-06	185	54	5	808d5e880069aff8866cd2c733b9fe568a37701f
ToppCell	367C-Endothelial_cells-Endothelial-D\|367C / Donor, Lineage, Cell class and subclass (all cells)	SELE VWF ADAMTS9 RAPGEF4 CCN2	3.15e-06	187	54	5	1342bc614bc4045263c2eb0a535a1dd6c64e7abe
ToppCell	367C-Endothelial_cells-Endothelial-D-\|367C / Donor, Lineage, Cell class and subclass (all cells)	SELE VWF ADAMTS9 RAPGEF4 CCN2	3.15e-06	187	54	5	7aa206262b14b9f2aaa99e59da38b96c3594d2c9
ToppCell	Endothelial-A-Donor_03\|World / lung cells shred on cell class, cell subclass, sample id	SELE VWF ACKR3 RAPGEF4 CCN2	3.15e-06	187	54	5	fd93f3f4b82dae3bf4eef245bfedc2a9e3251b61
ToppCell	Endothelial-A-SSc-ILD_02\|World / lung cells shred on cell class, cell subclass, sample id	SELE VWF ADAMTS9 RAPGEF4 CCN2	3.15e-06	187	54	5	febe0b99a6a815ce687160a0e7af55228b1d5beb
ToppCell	390C-Endothelial_cells-Endothelial-D-\|390C / Donor, Lineage, Cell class and subclass (all cells)	SELE RSPO3 VWF RP1L1 CCN2	3.24e-06	188	54	5	50481192da0e9484accb7fcbf9e28a246bb3b80f
ToppCell	Control-Endothelial-VE_Peribronchial\|Control / Disease state, Lineage and Cell class	SELE VWF ADAMTS9 RAPGEF4 CCN2	3.24e-06	188	54	5	f5b7dbc89f992c13280d36a34935be83906b1bc0
ToppCell	COVID-19-lung-Vein_EC\|lung / Disease (COVID-19 only), tissue and cell type	SELE ADAMTSL1 VWF ADAMTS9 RAPGEF4	3.24e-06	188	54	5	d582b76fc2faac526c9bf97503041129e1a6a211
ToppCell	390C-Endothelial_cells-Endothelial-D\|390C / Donor, Lineage, Cell class and subclass (all cells)	SELE RSPO3 VWF RP1L1 CCN2	3.24e-06	188	54	5	30bbd00297de7a2e3e6008aaf37ec0d0617315eb
ToppCell	Control-Endothelial-VE_Venous\|World / Disease state, Lineage and Cell class	SELE VWF ADAMTS9 RAPGEF4 CCN2	3.32e-06	189	54	5	f83f7521e377ded1522639e9a35c98b3e2725bac
ToppCell	LPS_only-Endothelial-Endothelial-Alv_Gen_Intermediate\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ADAMTSL1 VWF P2RX7 DTL RAPGEF4	3.32e-06	189	54	5	e82211b9dc7540e7a183be2cbcfae39fdf503949
ToppCell	3'-Distal_airway-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_systemic\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SELE RSPO3 VWF ADAMTS9 ACKR3	3.32e-06	189	54	5	e002dbb2138a6264be23f3b8148275a0cef351ef
ToppCell	COVID-19-lung-Vein_EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SELE ADAMTSL1 VWF ADAMTS9 RAPGEF4	3.41e-06	190	54	5	1caeaef78326734c1e31a0c4739190d5c5a77b9e
ToppCell	Control-Endothelial-VE_Venous\|Endothelial / Disease state, Lineage and Cell class	SELE RSPO3 VWF ADAMTS9 CCN2	3.41e-06	190	54	5	4e30155203b4a8c5e496fcbe9348b67b98ebc625
ToppCell	LPS_only-Endothelial-Endothelial-Vein\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SELE VWF ADAMTS9 ACKR3 RAPGEF4	3.59e-06	192	54	5	52acaecd3703166f5ce3b328aff7c82bd142fee4
ToppCell	LPS-antiTNF-Endothelial-Endothelial-Activated_Gen_Cap\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SELE VWF ADAMTS9 DTL RAPGEF4	3.59e-06	192	54	5	0aeb5351275c0a91151ea2d52b2cdde172da6731
ToppCell	nucseq-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel-SVEC\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	SELE VWF ADAMTS9 RAPGEF4 CCN2	3.59e-06	192	54	5	c3dda7c48732b0b8bde36de282d64192f5e9b98f
ToppCell	nucseq-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel-VEC\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	SELE RSPO3 VWF ADAMTS9 RAPGEF4	3.68e-06	193	54	5	9ba688b35a9ead5d04691b3f3f15484f02dbbd0d
ToppCell	IPF-Endothelial-VE_Venous\|World / Disease state, Lineage and Cell class	SELE VWF ADAMTS9 RAPGEF4 CCN2	3.68e-06	193	54	5	ef66a46e7ab44fcc4005a23416e6da478a4cce37
ToppCell	356C-Endothelial_cells-Endothelial-A_(Artery)\|356C / Donor, Lineage, Cell class and subclass (all cells)	SELE VWF ADAMTS9 RAPGEF4 CCN2	3.77e-06	194	54	5	2e5b195e02dcd5e9432b9a98b22e0478e65b9ba2
ToppCell	356C-Endothelial_cells-Endothelial-A_(Artery)-\|356C / Donor, Lineage, Cell class and subclass (all cells)	SELE VWF ADAMTS9 RAPGEF4 CCN2	3.77e-06	194	54	5	b6b5b0ab506b05a005ba8a05a3c7f4c725ba9200
ToppCell	LPS_only-Endothelial-Endothelial-Activated_Gen_Cap\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SELE VWF ADAMTS9 DTL RAPGEF4	3.87e-06	195	54	5	56efeb58df19f357d7d5ce87348d4f196a595421
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SELE ADAMTSL1 VWF ADAMTS9 RAPGEF4	3.87e-06	195	54	5	818bc18c5834238e5f733cac6fe928ed0788f57d
ToppCell	(6)_Endothelial-D\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	SELE VWF ADAMTS9 RAPGEF4 CCN2	3.87e-06	195	54	5	c0005a5f2dc63a0cc254c45ac89a2f42df6f8bde
ToppCell	ASK428-Endothelial-Endothelium\|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq	SELE VWF ADAMTS9 RAPGEF4 CCN2	3.96e-06	196	54	5	b1a81eddb91fb462360692b7b0a3ba4a947eac40
ToppCell	5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_systemic-EC_venous_systemic_L.2.2.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SELE RSPO3 VWF ADAMTS9 CCN2	3.96e-06	196	54	5	d5d3028fcbfa251a206d17ec33b3b313968f9d79
ToppCell	3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating-Alveolar_macrophage_proliferating_L.1.0.7.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SELE VWF ADAMTS9 ACKR3 DTL	3.96e-06	196	54	5	eb8c9a4a5eb21d43ff7b25deae5896c236f669b9
ToppCell	5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary-EC_venous_pulmonary_L.2.2.1.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SELE RSPO3 VWF ADAMTS9 CCN2	4.06e-06	197	54	5	8437c33e2c4a10a1b95343431e48d5e820b1f742
ToppCell	5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SELE RSPO3 VWF ADAMTS9 CCN2	4.06e-06	197	54	5	0542badae77d2f606c13cfaf361319495c354351
ToppCell	(4)_Blood_vessel\|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)	SELE RSPO3 VWF ADAMTS9 CCN2	4.06e-06	197	54	5	1b82979a41ef46c814c82527a585900586d71260
ToppCell	distal-Endothelial-Bronchial_Vessel_1\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	SELE VWF ADAMTS9 RAPGEF4 CCN2	4.06e-06	197	54	5	f45a93b5ad80a16b760acbaa6467648ffc05a0d3
ToppCell	3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary-EC_venous_pulmonary_L.2.2.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SELE VWF ADAMTS9 ACKR3 DTL	4.06e-06	197	54	5	76b61e60a757e58b465569538e632d6d9953e89a
ToppCell	356C-Endothelial_cells\|356C / Donor, Lineage, Cell class and subclass (all cells)	SELE VWF ADAMTS9 RAPGEF4 CCN2	4.06e-06	197	54	5	f20eda534b2b28986790b28ce150ca3ba067593a
ToppCell	390C-Endothelial_cells\|390C / Donor, Lineage, Cell class and subclass (all cells)	SELE VWF ADAMTS9 RAPGEF4 CCN2	4.06e-06	197	54	5	aa381acea0f7882d39435a6f713386bf0588b5f8
ToppCell	metastatic_Brain-Endothelial_cells\|metastatic_Brain / Location, Cell class and cell subclass	SELE VWF ADAMTS9 RAPGEF4 CCN2	4.17e-06	198	54	5	97ef7946ef11ac93318c1dd46b548dc01e5a6aba
ToppCell	3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SELE RSPO3 VWF ADAMTS9 RAPGEF4	4.17e-06	198	54	5	3ae1e2b4ca77b94eaa24a8c990780aff47dface6
ToppCell	Bronchial_Biopsy-Endothelial-Endothelial\|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X	SELE RSPO3 VWF ADAMTS9 RAPGEF4	4.17e-06	198	54	5	d4a4e5c358d26d09ff27541ce49d0db75c1cd08e
ToppCell	distal-1-Endothelial-Bronchial_Vessel_1\|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	SELE VWF ADAMTS9 RAPGEF4 CCN2	4.17e-06	198	54	5	5cd81fe1a21c0e1a7f0d5a62ddf8e422b05aedc7
ToppCell	IPF-Endothelial-VE_Peribronchial\|Endothelial / Disease state, Lineage and Cell class	SELE ADAMTSL1 VWF ADAMTS9 RAPGEF4	4.17e-06	198	54	5	b8bd1ba268480f54451648e01631b615a3401144
ToppCell	Bronchial_Biopsy-Endothelial\|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X	SELE RSPO3 VWF ADAMTS9 RAPGEF4	4.17e-06	198	54	5	ec80b05b8a1800c341b5741bf3e57213308398a7
ToppCell	3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary-EC_venous_pulmonary_L.2.2.1.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SELE RSPO3 VWF ADAMTS9 RAPGEF4	4.17e-06	198	54	5	fb70a649e4e2edb32967328c1085dc5999c29a33
ToppCell	metastatic_Brain-Endothelial_cells-Tumor_ECs\|metastatic_Brain / Location, Cell class and cell subclass	SELE VWF ADAMTS9 RAPGEF4 CCN2	4.17e-06	198	54	5	5e274f29cc796dae7d64d6035e904816c25f9914
ToppCell	3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SELE RSPO3 VWF ADAMTS9 RAPGEF4	4.17e-06	198	54	5	71ee440b1ac566db63d0b415c50a0ad064d14f15
ToppCell	distal-3-Endothelial-Bronchial_Vessel_1\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	SELE VWF ADAMTS9 RAPGEF4 CCN2	4.17e-06	198	54	5	00fdee373eaa43c9ce897f2ba2ecbe94cedea93a
ToppCell	3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_systemic\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SELE VWF ADAMTS9 RAPGEF4 CCN2	4.27e-06	199	54	5	6a7ecc3a68b9cfc49e50abaeb16e2eee3795377e
ToppCell	Parenchymal-10x5prime-Endothelial-Endothelia_vascular-VE_systemic_venous\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	SELE VWF ADAMTS9 RAPGEF4 CCN2	4.27e-06	199	54	5	6fb81388c5045e81c3849a7136bdff3f953f044e
ToppCell	Lung_Parenchyma-Severe-Myeloid-Macrophage-Macrophages-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SELE VWF ADAMTS9 RAPGEF4 CCN2	4.37e-06	200	54	5	e6d36be0c4c569e27303bb4e4f34cd2187e9759d
ToppCell	Biopsy_Other_PF-Endothelial\|Biopsy_Other_PF / Sample group, Lineage and Cell type	SELE VWF ADAMTS9 RAPGEF4 CCN2	4.37e-06	200	54	5	f9916134486fb1dac55f5e7e8deb35e7a3b85770
ToppCell	Bronchial-10x5prime-Endothelial-Endothelia_vascular-VE_pulmonary_venous\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	SELE RSPO3 VWF ADAMTS9 RAPGEF4	4.37e-06	200	54	5	84e145619a500530f42ed0fe72468ae95f4cbf1e
ToppCell	Parenchyma_COVID-19-Endothelial-TX-Macrophages\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	SELE VWF ADAMTS9 RAPGEF4 CCN2	4.37e-06	200	54	5	c0c51719cf81512c50bfcc2fed883c867e522d2a
ToppCell	Biopsy_Other_PF-Endothelial-Endothelial_cells\|Biopsy_Other_PF / Sample group, Lineage and Cell type	SELE VWF ADAMTS9 RAPGEF4 CCN2	4.37e-06	200	54	5	40d57a383c79d3365e033d08efd9371f0bc5bf55
ToppCell	Lung_Parenchyma-Severe-Myeloid-Macrophage\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	SELE VWF ADAMTS9 RAPGEF4 CCN2	4.37e-06	200	54	5	758840c31f2ddd7ccf7bf13252ebb48d33e89479
ToppCell	Lung_Parenchyma-Severe-Endothelial-Endothelial-Endothelial-1\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	SELE VWF ADAMTS9 RAPGEF4 CCN2	4.37e-06	200	54	5	27507c4b41d45c7cc50e4993169c0302be22ee34
ToppCell	3'-Adult-LargeIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SELE VWF ADAMTS9 RAPGEF4 CCN2	4.37e-06	200	54	5	cee07d9370656e1c428a7a9e9fbd175129901374
ToppCell	Parenchyma_COVID-19-Endothelial-TX-Endothelial-1\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	SELE VWF ADAMTS9 RAPGEF4 CCN2	4.37e-06	200	54	5	b65fb8d378abd91cdabf5faac5f4b90d527f8c44
ToppCell	Lung_Parenchyma-Severe-Endothelial-Endothelial-Endothelial-1-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SELE VWF ADAMTS9 RAPGEF4 CCN2	4.37e-06	200	54	5	2cb6e35add34b9dc564ebcf5d3cbc761325ca9f4
ToppCell	Bronchial-10x5prime-Endothelial-Endothelia_vascular-VE_systemic_venous\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	SELE VWF ADAMTS9 RAPGEF4 CCN2	4.37e-06	200	54	5	a3b09580738783c6bff31ea33d5188912e56b8a7
ToppCell	3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_systemic-EC_venous_systemic_L.2.2.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SELE VWF ADAMTS9 RAPGEF4 CCN2	4.37e-06	200	54	5	310c75e13be9194312a8b686804edcf13d44caf5
ToppCell	Lung_Parenchyma-Severe-Myeloid-Macrophage-Macrophages\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	SELE VWF ADAMTS9 RAPGEF4 CCN2	4.37e-06	200	54	5	c37fe06a94e5779c56e01389869bb432d3bbaebc
ToppCell	LV-03._Atrial_Cardiomyocyte\|LV / Chamber and Cluster_Paper	MYOM1 TESMIN PHF24 CMYA5	1.37e-05	120	54	4	3b77bd0e3630cdd45001cecf5e47660a90ebc92e
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_bronchial_vessel-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SELE VWF ADAMTS9 RAPGEF4	4.56e-05	163	54	4	ba7d02db0f0e2f9916ec8db52c067c87b6917c23
ToppCell	Endothelial-endothelial_cell_of_bronchial_vessel\|World / Lineage, Cell type, age group and donor	SELE VWF ADAMTS9 RAPGEF4	4.78e-05	165	54	4	84e553d699ac56df89a77248f7308b9133e1b683
ToppCell	facs-Lung-3m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l9\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TNFRSF25 SEPTIN1 ZFYVE26 CHRM4	5.01e-05	167	54	4	38b1f052d663fa8f407c54bdd2060216f26feb0e
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SELE VWF DTL RAPGEF4	5.13e-05	168	54	4	37249f38f8f04ec5743097259de67b106ca2b02f
ToppCell	Adult-Endothelial-endothelial_cell_of_vein-D175\|Adult / Lineage, Cell type, age group and donor	SELE VWF RAPGEF4 CCN2	5.25e-05	169	54	4	e1f0298236e4a1c59077c14f0dd29a78fac12648
ToppCell	Ionocyte-iono-1\|World / Class top	CMTR1 P2RX7 AGL RAPGEF4	5.25e-05	169	54	4	4b68bcb4b5fc3cd2db23cd4edace7444aa2d605c
ToppCell	Adult-Endothelial-endothelial_cell_of_bronchial_vessel-D122\|Adult / Lineage, Cell type, age group and donor	SELE VWF ADAMTS9 RAPGEF4	5.37e-05	170	54	4	a99cb3d21f8eb926886340ea99491e078e607648
ToppCell	Control-Endothelial_cells-Systemic_venous_endothelial_cells\|Control / group, cell type (main and fine annotations)	SELE VWF ADAMTS9 RAPGEF4	5.62e-05	172	54	4	c55dce1ed3ed7312394b4e050e1de852a994e130
ToppCell	Endothelial-A-IPF_03\|World / lung cells shred on cell class, cell subclass, sample id	SELE ADAMTSL1 VWF RAPGEF4	5.62e-05	172	54	4	a3201773a25832e92dd113fad165f1ecd37f5e91
ToppCell	facs-Lung-nan-3m-Lymphocytic-CD8-positive,_alpha-beta_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNFRSF25 SEPTIN1 RWDD2B CHRM4	5.88e-05	174	54	4	1c073177c1753e3b91ef8fd9e95230a1d13c82f3
ToppCell	PND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYOM1 SUSD5 DTL CCN2	5.88e-05	174	54	4	9f2e253694eb5860c00528fda31c305c6de8a2a1
ToppCell	Adult-Endothelial-endothelial_cell_of_vein-D231\|Adult / Lineage, Cell type, age group and donor	SELE RSPO3 VWF RAPGEF4	5.88e-05	174	54	4	2dd647c4fdf99fd1f7b838efef01baf2cbc3446d
ToppCell	facs-Lung-nan-3m-Lymphocytic-CD8+_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNFRSF25 SEPTIN1 RWDD2B CHRM4	5.88e-05	174	54	4	5491ad5c144baf2ef9b1c58eb720c872d14feb15
ToppCell	368C-Endothelial_cells-Endothelial-D\|368C / Donor, Lineage, Cell class and subclass (all cells)	SELE VWF ADAMTS9 RAPGEF4	6.01e-05	175	54	4	c4088b5f9fa145869cf5dd8bee7680b1c8fada42
ToppCell	368C-Endothelial_cells-Endothelial-D-\|368C / Donor, Lineage, Cell class and subclass (all cells)	SELE VWF ADAMTS9 RAPGEF4	6.01e-05	175	54	4	ca0d3e3a0a271cccdd3881b055fecb626712478d
ToppCell	356C-Endothelial_cells-Endothelial-D\|356C / Donor, Lineage, Cell class and subclass (all cells)	SELE VWF ADAMTS9 CCN2	6.28e-05	177	54	4	a0b172f40e0df97a288a5549ae7066697ad469b3
ToppCell	356C-Endothelial_cells-Endothelial-D-\|356C / Donor, Lineage, Cell class and subclass (all cells)	SELE VWF ADAMTS9 CCN2	6.28e-05	177	54	4	ab8f09e118e4df696b0b4d33f013da020bdbd351
ToppCell	E16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_G2M\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RSPO3 MYOM1 ENPP3 CCN2	6.42e-05	178	54	4	9fc5688cf705a74398d24e10e0aab4758612e72b
ToppCell	Endothelial-A-IPF_04\|World / lung cells shred on cell class, cell subclass, sample id	VWF ACKR3 RAPGEF4 CCN2	6.42e-05	178	54	4	2f2602b9305d55f25afa9861dd6c6347ae179337
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5-Exc_L4-5_RORB_HNRNPA1P46\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RSPO3 ADAMTSL1 CCN2 LRRK1	6.42e-05	178	54	4	b863fc85d2449f25e6cea289459a7bb1f89583fd
ToppCell	5'-GW_trimst-2-SmallIntestine-Endothelial-blood_vessel_EC-arterial_capillary\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SELE VWF ADAMTS9 SMAD7	6.70e-05	180	54	4	755050226eeb1991ee7f0d15e39d0458f3e4a791
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_vein-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	RSPO3 VWF RAPGEF4 CCN2	6.70e-05	180	54	4	27e8bbee388e64dd79d70b160b76d45b1f398006
ToppCell	COVID-19-Endothelial_cells-Endothelial_cells_(other)\|COVID-19 / group, cell type (main and fine annotations)	SELE VWF ADAMTS9 RAPGEF4	6.85e-05	181	54	4	26eb4ee57a70dbf54e096b73129fda9dfda1f6ec
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SELE ADAMTSL1 VWF ACKR3	6.85e-05	181	54	4	cef034030e6b029a49ae56be37ea1fac1a5c350e
Drug	Nf279	VWF P2RX3 P2RX7	5.62e-06	15	54	3	CID000004467
Disease	scoliosis (implicated_via_orthology)	ADAMTS9 SSPOP	2.92e-05	5	51	2	DOID:0060249 (implicated_via_orthology)
Disease	alkaline phosphatase measurement	SELE RSPO3 ADAMTSL1 P2RX7 INPP5E ENPP3 RP1L1 DMBT1 SMAD7	5.40e-05	1015	51	9	EFO_0004533
Disease	argininate measurement	IGF2R DNAJC16	8.15e-05	8	51	2	EFO_0800055
Disease	Paroxysmal atrial fibrillation	SELE ZNF462 VWF SMAD7	1.55e-04	156	51	4	C0235480
Disease	familial atrial fibrillation	SELE ZNF462 VWF SMAD7	1.55e-04	156	51	4	C3468561
Disease	Persistent atrial fibrillation	SELE ZNF462 VWF SMAD7	1.55e-04	156	51	4	C2585653
Disease	Atrial Fibrillation	SELE ZNF462 VWF SMAD7	1.71e-04	160	51	4	C0004238
Disease	cortical surface area measurement	RSPO3 ADAMTSL1 ADAMTS9 INPP5E ACKR3 ENPP3 RP1L1 PKHD1 MED13L	4.46e-04	1345	51	9	EFO_0010736
Disease	Congenital hernia of foramen of Morgagni	IGF2R CCN2	4.92e-04	19	51	2	C0265699
Disease	Congenital hernia of foramen of Bochdalek	IGF2R CCN2	4.92e-04	19	51	2	C0265700
Disease	bone density	RSPO3 ADAMTSL1 TESMIN DMBT1 MED13L	5.48e-04	388	51	5	EFO_0003923
Disease	Congenital diaphragmatic hernia	IGF2R CCN2	6.02e-04	21	51	2	C0235833
Disease	body surface area	ZNF462 BRPF3 DTL PKHD1 MED13L SMAD7	8.19e-04	643	51	6	EFO_0022196
Disease	serum gamma-glutamyl transferase measurement	RSPO3 P2RX7 DNAJC16 EPHA2 RP1L1 PKHD1 RWDD2B	9.44e-04	914	51	7	EFO_0004532
Disease	hematocrit	ZNF462 RSPO3 BRPF3 DNAJC16 PKHD1 DMBT1 SMAD7	1.69e-03	1011	51	7	EFO_0004348

Protein segments in the cluster

Peptide	Gene	Start	Entry
LVNTFCQSCIPDTVW	CHRM4	421	P08173
WTSCVIKDNPFCEFI	ASB15	471	Q8WXK1
VCAIWIPEVCFANTV	BRPF3	291	Q9ULD4
QEVTSVCWCPSDFTK	DTL	361	Q9NZJ0
VTAVSEVFLCCEQGW	RFT1	481	Q96AA3
EEEGDTCTICLEQWT	RFWD3	281	Q6PCD5
TWDFVDPTQRVSCSC	MED13L	411	Q71F56
LIWFCSEVECSTVTT	INPP5E	381	Q9NRR6
FNVSVVNTTCFWIEC	CD164	71	Q04900
VCTFENENTEWCLAV	LRRK1	1971	Q38SD2
FIPEAWSACTVTCGV	ADAMTSL1	526	Q8N6G6
ITSDWCFSCIHIEPV	DNAJC16	166	Q9Y2G8
WCSPLDQVCISNEVV	LY6L	46	H3BQJ8
WTEEVPSCQVVKCSS	SELE	481	P16581
CEVYDPATETWTELC	KLHL7	451	Q8IXQ5
TCEVSAWCPIEAVEE	P2RX7	161	Q99572
SCSLQPCEYVWITGE	ADAMTS9	1606	Q9P2N4
CCWDFEDTCVESTRI	ENPP3	81	O14638
CEEWVCDEPKDQTVV	CCN2	161	P29279
VYSVTCEQCWPESGE	EPHA2	361	P29317
TPVIRAEDCTVCWNT	CMYA5	3806	Q8N3K9
DISWPCNSSDCIVVD	ACKR3	16	P25106
SACTDSWRVVDCPES	KRTAP10-10	11	P60014
CDDSWTIQEAEVVCR	DMBT1	1911	Q9UGM3
QEVEVCCPWELSTLV	PRAMEF8	206	Q5VWM4
ACEQVSWFPECTTEI	CMTR1	151	Q8N1G2
NCSTDLTWFEHIVPC	LIPT2	171	A6NK58
TCEIQGWCPTEVDTV	P2RX3	146	P56373
RPSSCISWEVVEATC	TESMIN	446	Q9Y4I5
SECDFVFEWETPVVC	IGF2R	1781	P11717
CCWENPQFSSTVLSE	USP9X	2306	Q93008
NEIQFWVVTEICLCS	RAPGEF4	821	Q8WZA2
RVVQDCSFAVCTTGW	SUSD5	76	O60279
ICEDTECAVPEAWTL	SSPOP	4246	A2VEC9
CCAVFSEAPNSWIVE	SLFN11	321	Q7Z7L1
SCDIVNLTEASIWCE	PKHD1	1236	P08F94
PVVNDEMCDVCEVWT	PHF24	126	Q9UPV7
VVCALWIPEVCFANT	BRPF1	351	P55201
SVDCSDCWLPVVKFI	SEPTIN1	101	Q8WYJ6
QEVEVCCPWELSTLV	PRAMEF7	206	Q5VXH5
FISSCPCWLEVIFNS	SMAD7	411	O15105
EVSVCFTSEEWACLG	ZNF197	221	O14709
DVWTLPDQCHTVTCQ	VWF	1891	P04275
VACSAALDCDPIWVS	RP1L1	1506	Q8IWN7
VPEGATWAEVTVCSC	TPP2	666	P29144
ECVSIVHCEVSEWNP	RSPO3	141	Q9BXY4
WFVECQVSQCVSSSP	TNFRSF25	121	Q93038
VVCVEGPQSACEEFW	RWDD2B	226	P57060
CRDCVFEAVSIWDIT	ZNF462	1371	Q96JM2
FVVCEECRITEWVSV	WNT10A	401	Q9GZT5
TVICVFNWAFEECPP	SIGLEC10	161	Q96LC7
WQTLRSCCVEDPSTV	ZFYVE26	1536	Q68DK2
CPFSCETQAWSIATI	AGL	1511	P35573
APSAVSECFKCEEWT	MYOM1	1021	P52179