Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
Domain-

ARHGAP42 ARHGAP26 KIF1B DOCK10 ARHGEF18 ARHGEF17 PLCE1

9.76e-043917572.30.29.30
DomainI-BAR_dom

ARHGAP42 ARHGAP26

1.21e-0313752IPR013606
DomainPH_dom-like

ARHGAP42 ARHGAP26 KIF1B DOCK10 ARHGEF18 ARHGEF17 PLCE1

1.60e-03426757IPR011993
DomainMyosin_N

MYH13 MYH7B

1.62e-0315752PF02736
DomainMyosin_N

MYH13 MYH7B

1.62e-0315752IPR004009
DomainPH

ARHGAP42 ARHGAP26 KIF1B DOCK10 ARHGEF18

2.28e-03229755PF00169
DomainMyosin_tail_1

MYH13 MYH7B

2.34e-0318752PF01576
DomainMyosin_tail

MYH13 MYH7B

2.34e-0318752IPR002928
DomainMyosin-like_IQ_dom

MYH13 MYH7B

2.60e-0319752IPR027401
Domain-

MYH13 MYH7B

2.60e-03197524.10.270.10
DomainBromodomain_CS

BAZ1B BRWD1

4.86e-0326752IPR018359
DomainPH

ARHGAP42 ARHGAP26 KIF1B DOCK10 ARHGEF18

5.21e-03278755SM00233
DomainPH_DOMAIN

ARHGAP42 ARHGAP26 KIF1B DOCK10 ARHGEF18

5.29e-03279755PS50003
DomainRho_GTPase_activation_prot

ARHGAP42 NF1 ARHGAP26

5.34e-0388753IPR008936
DomainPH_domain

ARHGAP42 ARHGAP26 KIF1B DOCK10 ARHGEF18

5.37e-03280755IPR001849
DomainFHA

KIF1B MKI67

5.62e-0328752SM00240
DomainFHA_DOMAIN

KIF1B MKI67

6.86e-0331752PS50006
DomainFHA

KIF1B MKI67

6.86e-0331752PF00498
Pubmed

Tagging genes with cassette-exchange sites.

ZFAT ARHGAP26 GTSE1 MKI67 BAZ1B KDM7A REXO1L1P SOCS7

8.05e-0733577815741177
Pubmed

Transgenic mouse proteomics identifies new 14-3-3-associated proteins involved in cytoskeletal rearrangements and cell signaling.

NF1 CORO2A RIMS3 ARHGEF18 PFKL HSPA2

9.53e-0714777616959763
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

UBR1 PPIG NF1 MAPT RBBP8 KIF1B GTSE1 MKI67 BAZ1B ZMYM3 ZNF687

1.09e-06774771115302935
Pubmed

Mouse screen reveals multiple new genes underlying mouse and human hearing loss.

URI1 NF1 MCPH1 MYH7B AFF3 CCDC18 BAZ1B ARHGEF18 ZC3HC1 KDM7A PFKL CCDC77 SOCS7

3.17e-061242771330973865
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

RIMS3 KIF1B OBSL1 DOCK10 MAST1 ARHGEF17 ZMYM3 PLCE1

3.42e-0640777812693553
Pubmed

Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

ZFAT MYH7B KIF1B PLCE1 BAHCC1

3.45e-0610377510819331
Pubmed

Extragonadal teratocarcinoma in chimeric mice.

BRCA2 HSPA2

4.84e-06277210490215
Pubmed

DNA end resection requires constitutive sumoylation of CtIP by CBX4.

RBBP8 CBX4

4.84e-06277228740167
Pubmed

Evaluation of estrogen receptor alpha and beta and progesterone receptor expression and correlation with clinicopathologic factors and proliferative marker Ki-67 in breast cancers.

ESR2 MKI67

4.84e-06277218234277
Pubmed

KIF1B and NF1 are the most frequently mutated genes in paraganglioma and pheochromocytoma tumors.

NF1 KIF1B

4.84e-06277228515046
Pubmed

Expression of estrogen receptor β and Ki 67 in benign & malignant human prostate lesions by immunohistochemistry.

ESR2 MKI67

4.84e-06277225527409
Pubmed

Maternal Hypertension-Related Genotypes and Congenital Heart Defects.

ARHGAP42 PLCE1

4.84e-06277232710738
Pubmed

Neuroblast differentiation during development and in neuroblastoma requires KIF1Bβ-mediated transport of TRKA.

NF1 KIF1B MKI67

5.72e-061677328637693
Pubmed

Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification.

BRCA2 GTSE1 AFF3 CBX4 CCDC77 ZNF687

1.03e-0522277637071664
Pubmed

Microcephalin regulates BRCA2 and Rad51-associated DNA double-strand break repair.

MCPH1 BRCA2

1.45e-05377219549900
Pubmed

Dendritic and axonal distribution of the microtubule-associated proteins MAP2 and tau in the cerebellum of the nervous mutant mouse.

MAPT HPS5

1.45e-0537723147150
Pubmed

Neurofibromatosis with male breast cancer--risk factor or co-incidence? Report of two rare cases.

NF1 BRCA2

1.45e-05377225267367
Pubmed

BRIT1/MCPH1 is essential for mitotic and meiotic recombination DNA repair and maintaining genomic stability in mice.

MCPH1 BRCA2

1.45e-05377220107607
Pubmed

Tau hyperphosphorylation correlates with reduced methylation of protein phosphatase 2A.

MAPT ESR2

1.45e-05377218586097
Pubmed

Immunoexpression of estrogen receptor-β and progesterone receptor in prostate adenocarcinoma, does it inhibit neoplastic proliferation and invasion?

ESR2 MKI67

1.45e-05377232108623
Pubmed

Progress in tailoring adjuvant endocrine therapy for postmenopausal women with early breast cancer.

ESR2 MKI67

1.45e-05377219593135
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

NF1 MAPT PARP8 KIF1B GTSE1 CCDC18 CBX4 PPIP5K2 ARHGEF17 PPP1R12C

2.01e-05861771036931259
Pubmed

Cereblon Regulates the Proteotoxicity of Tau by Tuning the Chaperone Activity of DNAJA1.

MAPT HSPA2

2.89e-05477233972400
Pubmed

Human Endometriosis Tissue Microarray Reveals Site-specific Expression of Estrogen Receptors, Progesterone Receptor, and Ki67.

ESR2 MKI67

2.89e-05477229629944
Pubmed

Identification of ARHGEF17, DENND2D, FGFR3, and RB1 mutations in melanoma by inhibition of nonsense-mediated mRNA decay.

DENND2D ARHGEF17

2.89e-05477218677770
Pubmed

Microcephaly family protein MCPH1 stabilizes RAD51 filaments.

MCPH1 BRCA2

2.89e-05477232735676
Pubmed

A BAR domain-mediated autoinhibitory mechanism for RhoGAPs of the GRAF family.

ARHGAP42 ARHGAP26

2.89e-05477218954304
Pubmed

TDRD5 is required for retrotransposon silencing, chromatoid body assembly, and spermiogenesis in mice.

PIWIL4 ODF1 HSPA2

3.66e-052977321383078
Pubmed

Polycomb Group Protein CBX7 Represses Cardiomyocyte Proliferation Through Modulation of the TARDBP/RBM38 Axis.

MKI67 CBX4 PCGF5

4.06e-053077337158107
Pubmed

Polymorphic variants in hereditary pancreatic cancer genes are not associated with pancreatic cancer risk.

MCPH1 BRCA2 RBBP8

4.49e-053177319690177
Pubmed

Hormone receptors expression in phyllodes tumors of the breast.

ESR2 MKI67

4.82e-05577222590818
Pubmed

The Central Domain of MCPH1 Controls Development of the Cerebral Cortex and Gonads in Mice.

MCPH1 MKI67

4.82e-05577236078123
Pubmed

Loss of p53 partially rescues embryonic development of Palb2 knockout mice but does not foster haploinsufficiency of Palb2 in tumour suppression.

BRCA2 MKI67

7.22e-05677221404276
Pubmed

BRCA1 and 53BP1 regulate reprogramming efficiency by mediating DNA repair pathway choice at replication-associated double-strand breaks.

BRCA2 RBBP8

7.22e-05677238554279
Pubmed

High-grade serous carcinomas arise in the mouse oviduct via defects linked to the human disease.

NF1 BRCA2

7.22e-05677228608929
Pubmed

PALB2 is an integral component of the BRCA complex required for homologous recombination repair.

BRCA2 RBBP8

7.22e-05677219369211
Pubmed

SAG/RBX2/ROC2 E3 ubiquitin ligase is essential for vascular and neural development by targeting NF1 for degradation.

NF1 MKI67

7.22e-05677222118770
Pubmed

NuRD subunit CHD4 regulates super-enhancer accessibility in rhabdomyosarcoma and represents a general tumor dependency.

MKI67 BAZ1B ZMYM3 ZNF687

8.31e-0510377432744500
Pubmed

MCPH1 regulates the neuroprogenitor division mode by coupling the centrosomal cycle with mitotic entry through the Chk1-Cdc25 pathway.

MCPH1 MKI67

1.01e-04777221947081
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

PPIG BRCA2 KIF1B GTSE1 HAUS5 PPIP5K2 CCDC77 HSPA2 BRWD1

1.12e-0485377928718761
Pubmed

RNF168-mediated localization of BARD1 recruits the BRCA1-PALB2 complex to DNA damage.

BRCA2 RBBP8

1.34e-04877234408138
Pubmed

DCAF8, a novel MuRF1 interaction partner, promotes muscle atrophy.

PPIG RIMS3 KIF1B MKI67 ZC3HC1 BRWD1

1.60e-0436477631391242
Pubmed

Stabilization of mutant BRCA1 protein confers PARP inhibitor and platinum resistance.

BRCA2 RBBP8

1.72e-04977224085845
Pubmed

Functional and mutational landscapes of BRCA1 for homology-directed repair and therapy resistance.

BRCA2 RBBP8

1.72e-04977228398198
Pubmed

Conserved overlapping gene arrangement, restricted expression, and biochemical activities of DNA polymerase ν (POLN).

BRCA2 RBBP8

1.72e-04977226269593
Pubmed

In vivo regulation of TGF-β by R-Ras2 revealed through loss of the RasGAP protein NF1.

NF1 MKI67

1.72e-04977222918885
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

NUAK1 ARHGAP26 HAUS5 KDM7A PPIP5K2 HPS5 ZNF687

1.74e-0452977714621295
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

MAPT HAUS5 OBSL1 BAZ1B CBX4 INO80D ZMYM3 ZNF687 BAHCC1 BRWD1

1.74e-041116771031753913
Pubmed

Cell organization, growth, and neural and cardiac development require αII-spectrin.

MAPT MKI67

2.15e-041077222159418
Pubmed

Estrogen receptor (ER) beta or p53 attenuates ERalpha-mediated transcriptional activation on the BRCA2 promoter.

BRCA2 ESR2

2.15e-041077218765668
Pubmed

MOV10L1 is necessary for protection of spermatocytes against retrotransposons by Piwi-interacting RNAs.

PIWIL4 HSPA2

2.15e-041077220547853
Pubmed

Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme.

UBR1 URI1 ERCC3 ARHGEF18 PFKL HSPA2

2.32e-0439077617643375
Pubmed

Modification of ovarian cancer risk by BRCA1/2-interacting genes in a multicenter cohort of BRCA1/2 mutation carriers.

BRCA2 RBBP8

2.63e-041177219584272
Pubmed

Immune-related zinc finger gene ZFAT is an essential transcriptional regulator for hematopoietic differentiation in blood islands.

ZFAT MKI67

2.63e-041177220660741
Pubmed

Proteomics analysis of Ring1B/Rnf2 interactors identifies a novel complex with the Fbxl10/Jhdm1B histone demethylase and the Bcl6 interacting corepressor.

CBX4 PCGF5 ZNF687

2.80e-045777317296600
Pubmed

The cell proliferation antigen Ki-67 organises heterochromatin.

ERCC3 NF1 HAUS5 MKI67 DOCK10 ARHGEF18

3.03e-0441077626949251
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

NF1 CORO2A MAPT ARHGAP26 KIF1B MAST1 ZC3HC1 PFKL ARHGEF17 HSPA2 PPP1R12C

3.04e-041431771137142655
Pubmed

Genetically engineered mouse models of brain cancer and the promise of preclinical testing.

NF1 BRCA2

3.15e-041277219076778
Pubmed

CAMSAP1 breaks the homeostatic microtubule network to instruct neuronal polarity.

MAPT MKI67

3.15e-041277232839317
Pubmed

Molecular Characterization of Nodose Ganglia Development Reveals a Novel Population of Phox2b+ Glial Progenitors in Mice.

MAPT MKI67

3.15e-041277238830761
Pubmed

Interplay between Polo kinase, LKB1-activated NUAK1 kinase, PP1βMYPT1 phosphatase complex and the SCFβTrCP E3 ubiquitin ligase.

NUAK1 PPP1R12C

3.15e-041277224785407
Pubmed

Mouse models in tumor suppression.

NF1 BRCA2

3.15e-04127729917000
Pubmed

A cochlear progenitor pool influences patterning of the mammalian sensory epithelium via MYBL2.

MKI67 PORCN

3.15e-041277239254648
Pubmed

Multifactorial contributions to an acute DNA damage response by BRCA1/BARD1-containing complexes.

BRCA2 RBBP8

3.15e-041277216391231
Pubmed

The KIF3 motor transports N-cadherin and organizes the developing neuroepithelium.

KIF1B MKI67

3.15e-041277215834408
Pubmed

SUMOylation activates large tumour suppressor 1 to maintain the tissue homeostasis during Hippo signalling.

BRCA2 MKI67

3.15e-041277234267330
Pubmed

Innate neural stem cell heterogeneity determines the patterning of glioma formation in children.

NF1 MKI67

3.15e-041277222789544
Pubmed

Pax6 interactions with chromatin and identification of its novel direct target genes in lens and forebrain.

FAT4 KIF1B

3.15e-041277223342162
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

BRCA2 RBBP8 KIF1B OBSL1 BAZ1B CBX4 ZMYM3

3.30e-0458877738580884
Pubmed

A proteomic investigation of ligand-dependent HSP90 complexes reveals CHORDC1 as a novel ADP-dependent HSP90-interacting protein.

URI1 HSPA2 PLCE1

3.42e-046177319875381
Pubmed

hnRNPU is required for spermatogonial stem cell pool establishment in mice.

MKI67 PIWIL4

3.71e-041377238625792
Pubmed

SWI/SNF chromatin remodeling complex is required for initiation of sex-dependent differentiation in mouse germline.

MKI67 PIWIL4

3.71e-041377234912016
Pubmed

Involvement of SF-1 in neurogenesis and neuronal migration in the developing neocortex.

ESR2 MKI67

3.71e-041377226067405
Pubmed

Family with sequence similarity 60A (FAM60A) protein is a cell cycle-fluctuating regulator of the SIN3-HDAC1 histone deacetylase complex.

MKI67 PFKL BAHCC1

3.94e-046477322865885
Pubmed

The E3 ubiquitin ligase APC/CCdh1 degrades MCPH1 after MCPH1-βTrCP2-Cdc25A-mediated mitotic entry to ensure neurogenesis.

MCPH1 OBSL1 CCDC77

4.13e-046577329150431
Pubmed

Tbx5 is required for avian and Mammalian epicardial formation and coronary vasculogenesis.

MKI67 FREM3

4.33e-041477225245104
Pubmed

The RNA helicase MOV10L1 binds piRNA precursors to initiate piRNA processing.

PIWIL4 ODF1

4.99e-041577225762440
Pubmed

Developmental Requirement of Homeoprotein Otx2 for Specific Habenulo-Interpeduncular Subcircuits.

MAPT MKI67

4.99e-041577230593496
Pubmed

Primary Autosomal Recessive Microcephalies and Seckel Syndrome Spectrum Disorders – RETIRED CHAPTER, FOR HISTORICAL REFERENCE ONLY

MCPH1 RBBP8

5.69e-041677220301772
Pubmed

Neuronal-specific deficiency of the splicing factor Tra2b causes apoptosis in neurogenic areas of the developing mouse brain.

MAPT MKI67

5.69e-041677224586484
Pubmed

Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.

ERCC3 HAUS5 CCDC18 ZC3HC1 CBX4 CCDC77 ZNF687

5.72e-0464577725281560
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

UBR1 OBSL1 DOCK10 PFKL PPIP5K2 HPS5 PLCE1

5.98e-0465077738777146
Pubmed

BRCA1 and BRCA2 tumor suppressors in neural crest cells are essential for craniofacial bone development.

BRCA2 MKI67

6.44e-041777229718910
Pubmed

Cbx4 regulates the proliferation of thymic epithelial cells and thymus function.

MKI67 CBX4

6.44e-041777223362346
Pubmed

Structural basis and sequence rules for substrate recognition by Tankyrase explain the basis for cherubism disease.

FAT4 PPP1R12C

6.44e-041777222153077
Pubmed

The expression pattern of nuclear receptors during cerebellar development.

ESR2 MKI67

6.44e-041777217205580
Pubmed

NANOS2 promotes male germ cell development independent of meiosis suppression.

MKI67 PIWIL4

7.23e-041877224183939
Pubmed

Novel susceptibility loci for second primary tumors/recurrence in head and neck cancer patients: large-scale evaluation of genetic variants.

BRCA2 MKI67

7.23e-041877219584075
Pubmed

Fat1 interacts with Fat4 to regulate neural tube closure, neural progenitor proliferation and apical constriction during mouse brain development.

FAT4 MKI67

7.23e-041877226209645
Pubmed

Wilms Tumor Predisposition

NF1 BRCA2

7.23e-041877220301471
Pubmed

Requirement of FAT and DCHS protocadherins during hypothalamic-pituitary development.

FAT4 MKI67

7.23e-041877233108146
Pubmed

Phosphopeptide binding specificities of BRCA1 COOH-terminal (BRCT) domains.

RBBP8 KIF1B

8.07e-041977214578343
Pubmed

Treatment during a developmental window prevents NF1-associated optic pathway gliomas by targeting Erk-dependent migrating glial progenitors.

NF1 MKI67

8.07e-041977234428430
Pubmed

Functional Cooperation of α-Synuclein and Tau Is Essential for Proper Corticogenesis.

MAPT MKI67

8.07e-041977235906071
Pubmed

Transient inhibition of the ERK pathway prevents cerebellar developmental defects and improves long-term motor functions in murine models of neurofibromatosis type 1.

NF1 MKI67

8.07e-041977225535838
Pubmed

Distinct regulatory cascades govern extraocular and pharyngeal arch muscle progenitor cell fates.

MYH13 MKI67

8.96e-042077219531352
Pubmed

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.

ERCC3 NF1 MYH13 NUAK1 AFF3 OBSL1 PCGF5 ZNF687

9.12e-0491077836736316
Pubmed

The ubiquitin ligase Uhrf2 is a master regulator of cholesterol biosynthesis and is essential for liver regeneration.

MKI67 BAZ1B BRWD1

9.36e-048677337253089
Pubmed

Molecular Profiling Reveals Involvement of ESCO2 in Intermediate Progenitor Cell Maintenance in the Developing Mouse Cortex.

GTSE1 MKI67 ZNF687

9.68e-048777333798452
Pubmed

Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.

RBBP8 MKI67 BAZ1B CBX4 ZNF687

9.76e-0434177532971831
InteractionPMVK interactions

NF1 MCPH1 MAPT ESR2 MKI67 ZC3HC1

1.92e-06101746int:PMVK
InteractionYWHAZ interactions

NF1 CORO2A MAPT ESR2 PARP8 RIMS3 KIF1B CCDC18 OBSL1 MAST1 ARHGEF18 CBX4 PFKL PPIP5K2 HSPA2 PCGF5 PPP1R12C

4.34e-0613197417int:YWHAZ
InteractionFOXP4 interactions

ESR2 MKI67 PFKL ZMYM3 ZNF687

3.03e-0598745int:FOXP4
InteractionPNMA2 interactions

PPIG KIF1B GTSE1 MAST1 CBX4 ZNF865 ZNF687

3.78e-05251747int:PNMA2
InteractionAPBA1 interactions

UBR1 MAPT KIF1B GTSE1 MKI67

3.85e-05103745int:APBA1
InteractionYWHAG interactions

PPIG NF1 NUAK1 MAPT ESR2 PARP8 RIMS3 KIF1B GTSE1 CCDC18 CBX4 PPIP5K2 ARHGEF17 ZMYM3 PPP1R12C

3.98e-0512487415int:YWHAG
GeneFamilyZinc fingers|Zinc fingers PARP-type|Poly(ADP-ribose) polymerases

DNLZ ZC3HC1

1.07e-031559226
GeneFamilyMyosin heavy chains

MYH13 MYH7B

1.07e-03155921098
CoexpressionHE_LIM_SUN_FETAL_LUNG_C0_PERICYTE

ARHGAP42 MAPT ARHGAP26 ARHGEF17 TNFRSF21 HSPA2 PLCE1

1.60e-06195767M45684
ToppCellmyeloid-pro-pDC|World / Lineage and Cell class

BRCA2 GTSE1 MKI67 GAPT TNFRSF21 BAHCC1

1.20e-061977768918ee006b16f6b86ed33ce1dd5c0f01f51f88f5
ToppCellmild-pDC|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

ZFAT BRCA2 RIMS3 AFF3 GAPT TNFRSF21

1.20e-0619777615230a54fa5903dd728de1a0ad633bd2d2c7a04d
ToppCellsevere-pDC|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

ZFAT RIMS3 AFF3 GAPT CBX4 TNFRSF21

1.23e-061987763c4820a8391088682fb3e47b914f872533bae227
ToppCellLPS-antiTNF-Stromal_mesenchymal-Myocytic|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARHGAP42 MAPT ARHGEF17 TNFRSF21 PLCE1

7.59e-061567756365b69ede98bc866e996bc52736b00401aacf6f
ToppCellLPS-antiTNF-Stromal_mesenchymal-Myocytic-Pericyte_2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARHGAP42 MAPT ARHGEF17 TNFRSF21 PLCE1

7.83e-06157775bfec34182f052cf1c0d847ba53ea335d4d1190de
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SH3TC2 BRCA2 GTSE1 CCDC18 MKI67

9.96e-06165775eec2d327c94832d1390314c93ef6a2be4648478b
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SH3TC2 BRCA2 GTSE1 CCDC18 MKI67

1.06e-0516777550c29ea660bf07b890e4ac1a1985d0761d863dee
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SH3TC2 BRCA2 GTSE1 CCDC18 MKI67

1.12e-05169775b253a4a50c06d36228fcd5d856c57202cbac158f
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

BRCA2 GTSE1 AFF3 CCDC18 MKI67

1.12e-0516977554b13ab02b4c187f4754045ecfcf409749e7ccc0
ToppCell10x5'-blood-Myeloid_Dendritic-pDC|blood / Manually curated celltypes from each tissue

ZFAT AFF3 OBSL1 TNFRSF21 BAHCC1

1.15e-0517077559cb1262ff319349d42b11afbec2a9035b7b79f2
ToppCellCOVID_vent-Lymphocytic-Dendritic-pDC|COVID_vent / Disease condition, Lineage, Cell class and subclass

ZFAT RIMS3 AFF3 GAPT TNFRSF21

1.18e-05171775779c951d274ecbd1d546ac425d6c8e718623be5a
ToppCellCOVID_vent-Lymphocytic-Dendritic|COVID_vent / Disease condition, Lineage, Cell class and subclass

ZFAT RIMS3 AFF3 GAPT TNFRSF21

1.18e-05171775debbb071d260639b16269c94d172766908325c58
ToppCellCOVID-19_Mild-PLT_2|COVID-19_Mild / Disease Group and Platelet Clusters

ARHGAP42 MCPH1 GTSE1 HAUS5 ZC3HC1

1.25e-05173775d11705e56b6b21eec963ea224717f27680c781ed
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SH3TC2 BRCA2 GTSE1 CCDC18 MKI67

1.29e-0517477584da9faff088d05233183b425385beb054c92d1b
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SH3TC2 BRCA2 GTSE1 CCDC18 MKI67

1.29e-05174775dbb4e1a6c3319ce40f81bfd2d1745a88a2cc412e
ToppCell367C-Lymphocytic-NK_cells-Proliferating_NK_cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

ARHGAP42 BRCA2 RBBP8 GTSE1 MKI67

1.32e-051757750b1aaa028ba844d4bcb4509fdab8bee648373935
ToppCellNS-moderate-d_0-4-Myeloid-pDC|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ZFAT BRCA2 ESR2 GAPT ARHGEF17

1.40e-05177775de1ffe3df76100d46ca158bdd2fea2ebbd4656b4
ToppCellSevere-Lymphoid-pDC|Severe / Condition, Lineage, Cell class and cell subclass

ZFAT ESR2 AFF3 GAPT TNFRSF21

1.56e-051817752caecb7c5dcdad46fd02b4ffb73cb613ce835187
ToppCellSevere-Lymphoid-pDC-|Severe / Condition, Lineage, Cell class and cell subclass

ZFAT ESR2 AFF3 GAPT TNFRSF21

1.56e-05181775277ce4c49121da0990a5933b19d2c6af9bbe253e
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling-Cycling_Connecting_Tubule_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

BRCA2 GTSE1 CCDC18 MKI67 CCDC77

1.60e-05182775336cd05e46a741185ce3c59ee67a4b07fa6a5101
ToppCelldroplet-Lung-nan-18m-Myeloid-Proliferating_Classical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RBBP8 GTSE1 HAUS5 MKI67 GAPT

1.60e-0518277511494a66d986297b837332ee9d382b71b9f22591
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARHGAP42 MAPT ARHGEF17 TNFRSF21 PLCE1

1.64e-051837758a799807fbf24456a9811e0c64068187940a2f71
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARHGAP42 MAPT ARHGEF17 TNFRSF21 PLCE1

1.69e-05184775689a8af81a79a4bb3123cfa01958c953eab5de98
ToppCellfacs-Diaphragm-Limb_Muscle-18m-Lymphocytic-T_cell|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MCPH1 BRCA2 CORO2A MKI67 PFKL

1.69e-05184775185b49630da61cbf45c0926d1b992943296d2a54
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARHGAP42 MAPT RIMS3 ARHGEF17 PLCE1

1.69e-05184775327ff3ac8d2fecdd5d242bdc34f0dfdb1c59a68b
ToppCelldroplet-Lung-18m-Hematologic-myeloid-classical_monocyte_proliferating-classical_monocyte_proliferating_l33-52|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GTSE1 CCDC18 MKI67 GAPT GRAMD1C

1.73e-0518577547c69500877b851c0c9744f5e1ef2ee0bff99168
ToppCellBAL-Mild-Myeloid-pDC-pDC|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ZFAT ESR2 AFF3 GAPT TNFRSF21

1.73e-05185775f4588468e8654363f48adbe427dff10f16f1c7fe
ToppCellBAL-Mild-Myeloid-pDC-pDC-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ZFAT ESR2 AFF3 GAPT TNFRSF21

1.73e-051857753cb816fc9541c04b4436e21d984216cfbbacff98
ToppCellICU-NoSEP-Myeloid-pDC|ICU-NoSEP / Disease, Lineage and Cell Type

ZFAT RIMS3 AFF3 GAPT TNFRSF21

1.73e-051857757564a47df4a4e3af30d40aa0f48bd9d9c82358ae
ToppCellBAL-Mild-Myeloid-pDC|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ZFAT ESR2 AFF3 GAPT TNFRSF21

1.73e-05185775c2e70405969616c28fb6379ee318e17bbcef7b49
ToppCellMild-Lymphoid-pDC|Mild / Condition, Lineage, Cell class and cell subclass

ZFAT ESR2 AFF3 GAPT TNFRSF21

1.78e-051867757fa82972c726025d6402e5eb7bf0db3b699eba4c
ToppCellBAL-Mild-Myeloid-pDC-pDC|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

ZFAT ESR2 AFF3 GAPT TNFRSF21

1.78e-05186775b031f4e6867b6200b85f43276a34749bf5f4603f
ToppCellhealthy_donor-Lymphocytic-Dendritic|healthy_donor / Disease condition, Lineage, Cell class and subclass

ZFAT RIMS3 OBSL1 GAPT TNFRSF21

1.78e-05186775916f2aeea4989ba7a29e071e348a51010f010223
ToppCellBAL-Mild-Myeloid-pDC|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

ZFAT ESR2 AFF3 GAPT TNFRSF21

1.78e-05186775d2fbf53aac905c9896272ec5c2db28ee1a60f4be
ToppCellhealthy_donor-Lymphocytic-Dendritic-pDC|healthy_donor / Disease condition, Lineage, Cell class and subclass

ZFAT RIMS3 OBSL1 GAPT TNFRSF21

1.78e-0518677545f66619e45d590c7365a51782d4ac46b7d31fde
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1|TCGA-Pancreas / Sample_Type by Project: Shred V9

ARHGAP42 UBR1 PPIG HMCN1 SRFBP1

1.78e-0518677503db813598b67b1e08f759758a1c2023396921fa
ToppCellMild-Lymphoid-pDC-|Mild / Condition, Lineage, Cell class and cell subclass

ZFAT ESR2 AFF3 GAPT TNFRSF21

1.78e-051867751d05e73ae2ec0cc27f79e4fa40d6b21790059f80
ToppCellBAL-Mild-Myeloid-pDC-pDC-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ZFAT ESR2 AFF3 GAPT TNFRSF21

1.78e-0518677579aedd5aed72509a4925e9f6cb43bc0c798c86f5
ToppCellMild_COVID-19-Myeloid-pDC|Mild_COVID-19 / Disease group,lineage and cell class (2021.01.30)

ZFAT ESR2 AFF3 GAPT TNFRSF21

1.82e-0518777599c3c4a7b9179dce7982dc6516d561c952abc80e
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

BRCA2 GTSE1 CCDC18 MKI67 CCDC77

1.82e-05187775057569c9437219ecc396aa6e673b1178a2273837
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

BRCA2 GTSE1 CCDC18 MKI67 DOCK10

1.82e-0518777573931a5ea73799095daff100b5f18853c57c74dc
ToppCellcontrol-pDC|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

ZFAT RIMS3 OBSL1 GAPT TNFRSF21

1.82e-05187775c78aee98b32719aa45811b620fc97be1ecf5fd53
ToppCellE17.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_myogenic_precursor_(Axin2+)|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ARHGAP42 MAPT ARHGEF17 TNFRSF21 PLCE1

1.92e-0518977526cfe5b7e7f477f225f4e9f25f983f432f01e183
ToppCellE17.5-Mesenchymal-developing_mesenchymal_cell|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ARHGAP42 MAPT ARHGEF17 TNFRSF21 PLCE1

1.97e-051907752ab604d35456beba71c25511e0f819000e6642d2
ToppCellP07-Mesenchymal-developing_mesenchymal_cell|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ARHGAP42 MAPT MKI67 ARHGEF17 TNFRSF21

2.02e-05191775ddbc5f97f2aef19be4ad93db4139876c939b848e
ToppCellP07-Mesenchymal-developing_mesenchymal_cell-mesenchymal_myogenic_precursor_(Axin2+)|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ARHGAP42 MAPT DOCK10 ARHGEF17 TNFRSF21

2.02e-051917752ad717b59215ad8d933e9637d363b65d7298e5d4
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_myocytic-mes_pericyte_(14)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

MAPT ARHGAP26 ARHGEF17 HSPA2 PLCE1

2.07e-0519277555f95454399fd533df75db06584eaa48d6ee3830
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_pericyte_(14)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

MAPT ARHGAP26 ARHGEF17 HSPA2 PLCE1

2.07e-051927755000440dc1ed17e7474d340921bdff945646f27e
ToppCellhuman_hepatoblastoma-Tumor_cells-T1|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

BRCA2 GTSE1 CCDC18 MKI67 CCDC77

2.12e-051937754b9fa2a4424f8abe63fa7bee78db93dda04ab15f
ToppCellcontrol-pDC|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

ZFAT RIMS3 OBSL1 GAPT TNFRSF21

2.12e-0519377530a6559c9a9e8941861cb259b4836acccc427e68
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating-|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

BRCA2 GTSE1 CCDC18 MKI67 CBX4

2.12e-05193775e45ce9cf8421512b57f157c24b64793b47b4ba4b
ToppCellmild-pDC|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

ZFAT BRCA2 AFF3 GAPT TNFRSF21

2.34e-051977750cb00daa6943f7a7fb34a8fdf51188646af65686
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-Pericytes-Immature_pericyte|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ARHGAP42 MAPT ARHGEF17 HSPA2 PLCE1

2.34e-05197775fd65a9b41df618ff2a09d76dcf9f1ca3f3bdf52a
ToppCellwk_20-22-Mesenchymal-Myofibro_&_SMC-Pericyte|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

ARHGAP42 MAPT ARHGEF17 HSPA2 PLCE1

2.34e-0519777544cd1ece3633a31e8c9b667cd3cbc2749c06f478
ToppCellBiopsy_IPF-Immune-pDCs|Biopsy_IPF / Sample group, Lineage and Cell type

ZFAT RIMS3 AFF3 GAPT TNFRSF21

2.40e-05198775aa8943e6796f619406056cf763b751fe9a9a3e0c
ToppCellsevere-pDC|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

ZFAT RIMS3 AFF3 GAPT TNFRSF21

2.40e-0519877522da4a29b9ff8b94d98bc69b4632a2a58d5dd9e6
ToppCellwk_15-18-Mesenchymal-Myofibro_&_SMC-Pericyte|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

ARHGAP42 MAPT ARHGEF17 HSPA2 PLCE1

2.40e-0519877576d46950c11cb4708866db0da54ce00d5c0adab8
ToppCellSepsis-ICU-NoSEP-Myeloid-pDC|ICU-NoSEP / Disease, condition lineage and cell class

ZFAT RIMS3 AFF3 GAPT TNFRSF21

2.46e-05199775a199e67438eeed903d0996605591ec54400fdd66
ToppCelldistal-mesenchymal-Pericyte-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ARHGAP42 ARHGEF17 TNFRSF21 HSPA2 PLCE1

2.46e-05199775000d9b5f5a48e56f0733390adb3d7270c49a4a1a
ToppCelldistal-3-mesenchymal-Pericyte|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ARHGAP42 ARHGEF17 TNFRSF21 HSPA2 PLCE1

2.52e-05200775911db29f254bb697610e720ba78816e2c7f57933
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Pericyte|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

ARHGAP42 MAPT ARHGEF17 TNFRSF21 PLCE1

2.52e-05200775b5b5a32925f225610fe25a021a742d6397162863
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Pericyte-Pericyte_2|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

ARHGAP42 MAPT ARHGEF17 TNFRSF21 PLCE1

2.52e-05200775d2fcd3bd7c3223875f027eeb48ff621192a5f242
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Pericyte|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

ARHGAP42 MAPT ARHGEF17 TNFRSF21 PLCE1

2.52e-052007754e1e19214aeebbdca004de7faaf4cc9d18498591
ToppCellLPS_IL1RA-Mesenchymal_myocytic-Pericyte-Pericyte_2|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

ARHGAP42 MAPT ARHGEF17 TNFRSF21 PLCE1

2.52e-05200775cf883ba5dbe6350b93142d625a52b25ff2a8bb63
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW26-Stem_cells-Neuroepithelial_cell|GW26 / Sample Type, Dataset, Time_group, and Cell type.

BRCA2 GTSE1 CCDC18 MKI67 HSPA2

2.52e-05200775203b9a5de4430713da01b3331e69381db449a3a0
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW26-Stem_cells|GW26 / Sample Type, Dataset, Time_group, and Cell type.

BRCA2 GTSE1 CCDC18 MKI67 HSPA2

2.52e-05200775a854e19703dc920e48304541e2b06ed013292f3e
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Pericyte-Pericyte_2|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

ARHGAP42 MAPT ARHGEF17 TNFRSF21 PLCE1

2.52e-05200775786f1ae53e60b5ffbf4bfd393d10b802478148b3
ToppCellsevere-immature_Neutrophil|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

BRCA2 CORO2A KIF1B MKI67 PIWIL4

2.52e-052007755ee43386da8261d2e7602a152e6ba4338d844e08
ToppCellLPS_only-Mesenchymal_myocytic-Pericyte-Pericyte_2|LPS_only / Treatment groups by lineage, cell group, cell type

ARHGAP42 MAPT RIMS3 ARHGEF17 PLCE1

2.52e-0520077569edc375d85689300d1dbc1217fedc40063ecdcb
ToppCell368C-Epithelial_cells-Epithelial-B_(AT2)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

CORO2A CCDC18 DUSP19 CCDC77

3.58e-05107774410b37beffaf637a2a64c9d0ce7baf81f4bc667c
ToppCell368C-Epithelial_cells-Epithelial-B_(AT2)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

CORO2A CCDC18 DUSP19 CCDC77

3.58e-051077745bae4b3aede9bcbf7e88414e3453973cc8b0c3e7
ToppCellLPS_only-Unknown-Endothelial|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MAPT RIMS3 TNFRSF21 PLCE1

4.75e-05115774ad5298c2ad8bf94fa13c2e50b0799e929473ef59
ToppCellLPS_only-Unknown|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MAPT RIMS3 TNFRSF21 PLCE1

4.75e-051157747a733f6987b40ec497a03734b79ed5355ad3a2fc
ToppCellLPS_only-Unknown-Endothelial-Pericyte_2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MAPT RIMS3 TNFRSF21 PLCE1

4.75e-05115774c67145d3cd9243994a141749b426ff2a6dcc8d93
ToppCellTCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Diffuse|TCGA-Stomach / Sample_Type by Project: Shred V9

AFF3 DOCK10 GAPT ARHGEF18

7.42e-051297747d537680b0dfb764f7914d0475c66b678b5cb8d2
ToppCellPND07-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CORO2A MKI67 KDM7A PCGF5

1.20e-0414677445d7cb73776e60d22f335a651845e21e16948fcc
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

BRCA2 GTSE1 MKI67 MAST1

1.55e-04156774b3f10cd044f24807576e7d56e51df7064dbf6c50
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c12-FOXP3|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

SH3TC2 CCDC18 DOCK10 CCDC77

1.55e-04156774fbe23876f0899853cea3c5c4f3044a9cea064d5b
ToppCell356C-Myeloid-Dendritic-pDC|356C / Donor, Lineage, Cell class and subclass (all cells)

ARHGAP42 ZFAT GAPT ZNF891

1.55e-04156774d9d87368e43b24952e70f31f38425e15b716ff5b
ToppCellfacs-Lung-nan-3m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SH3TC2 BRCA2 KCNB2 GRAMD1C

1.70e-04160774f2cdee5a9e3b0eb125d6be7b5d239eb04333ae41
ToppCellCOVID_non-vent-Lymphocytic-Dendritic-pDC|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

ZFAT RIMS3 GAPT TNFRSF21

1.70e-0416077461f4cb4eb4313d8318aadbb99595a6cb7fd919f7
ToppCellCOVID_non-vent-Lymphocytic-Dendritic|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

ZFAT RIMS3 GAPT TNFRSF21

1.70e-0416077434b4f710cfcb6ec370b8b074f3cbfe272f392cec
ToppCell367C-Myeloid-Dendritic-cDC_proliferating_2|367C / Donor, Lineage, Cell class and subclass (all cells)

GTSE1 CCDC18 MKI67 CBX4

1.87e-041647740662cd9d21608efacc336e0a582859f3b9a4951d
ToppCell367C-Myeloid-Dendritic-pDC|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

ZFAT AFF3 TNFRSF21 ZNF891

1.87e-0416477495b800c78871354c859abaa832d778786ef7bcc0
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs-Plasmacytoid_DCs_L.1.5.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ZFAT RIMS3 AFF3 GAPT

1.92e-04165774e2a70dd5870fe8708bf630ed3e6eb3f295df0cdf
ToppCelldroplet-Lung-3m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l15|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ERCC3 LZTFL1 BAZ1B BAHCC1

1.92e-041657741d0f60bf47a40ac916f0fcb5532a968742a0edbb
ToppCellDividing_Macrophages-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

BRCA2 GTSE1 MKI67 MAST1

1.96e-04166774c503036f3c19ef186e1e62c9643c49dea3827f51
ToppCell5'-Adult-Appendix-Hematopoietic-T_cells-MAIT_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PARP8 HAUS5 MAST1 ZNF766

1.96e-04166774e4f14b2dd8c6199fa27cc3e3beeda681a3b5b889
ToppCell10x5'-Liver-Hematopoietic_progenitors|Liver / Manually curated celltypes from each tissue

BRCA2 GTSE1 MKI67 BAHCC1

1.96e-04166774ae967570248cf86ca3ddf55e33bcbb3e4e3684bc
ToppCell10x5'-Liver-Hematopoietic_progenitors-Cycling_pre-Myeloid-2|Liver / Manually curated celltypes from each tissue

BRCA2 GTSE1 MKI67 BAHCC1

1.96e-04166774a176e87aa6eec81d1fb79a028f759182d11b567d
ToppCell10x5'-Liver-Myeloid_Dendritic-pDC|Liver / Manually curated celltypes from each tissue

ZFAT AFF3 GAPT TNFRSF21

1.96e-0416677424dfa9f3e0842f9ab8350bf6a52ae0d10f2a0c44
ToppCell367C-Myeloid-Dendritic-pDC|367C / Donor, Lineage, Cell class and subclass (all cells)

ZFAT AFF3 TNFRSF21 ZNF891

2.01e-04167774650de8cd5df070639b8aa292aacead739cfdb02c
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c03-MKI67|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

RBBP8 GTSE1 MKI67 HSPA2

2.01e-041677749280558baddea51aae47f3383d895a9b0c6749a4
ToppCellfacs-MAT-Fat-18m-Myeloid-macrophage|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CORO2A DOCK10 GAPT TNFRSF21

2.01e-04167774c2952d8ba763374c5678b92825c8956fc3e3ecd2
ToppCellE18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ARHGAP42 ERCC3 MAPT TNFRSF21

2.01e-04167774b0eb7a40491dd2432f5282f578ce569df86d21a7
ToppCellNS-moderate-d_07-13-Myeloid-pDC|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ZFAT RIMS3 AFF3 GAPT

2.05e-04168774d03e91f0e0518b33555c0ec98124fc5ed0f11be5
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SH3TC2 BRCA2 GTSE1 MKI67

2.05e-04168774d35944fd9fea9934ce1e76b2b35d48e2300cca61
ToppCell(3)_DC_plasmacytoid|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

ZFAT GAPT TNFRSF21 ZNF891

2.05e-041687748a913db9b2a1a4ff96fb139734a3834e6aa263f1
ToppCell(3)_MNP-(3)_DC_plasmacytoid|(3)_MNP / Lung cell shreds - cell class (v4) and cell subclass (v4)

ZFAT AFF3 TNFRSF21 ZNF891

2.05e-0416877413c160ea1a19b47d2e7e2dae818c8dcde4e3e377
ToppCell390C-Myeloid-Dendritic-pDC|390C / Donor, Lineage, Cell class and subclass (all cells)

ZFAT AFF3 GAPT TNFRSF21

2.05e-041687745a2e7a52b7330dce30823695a7b9b26bc47a69ce
DiseaseJUVENILE MYELOMONOCYTIC LEUKEMIA

NF1 ARHGAP26

3.71e-054742607785
DiseaseJuvenile myelomonocytic leukemia

NF1 ARHGAP26

3.71e-054742cv:C0349639
DiseaseX-linked mental retardation with cerebellar hypoplasia and distinctive facial appearance (implicated_via_orthology)

ARHGAP42 ARHGAP26

3.71e-054742DOID:0080311 (implicated_via_orthology)
Diseasechronic obstructive pulmonary disease

MTHFSD HMCN1 KIF1B AFF3 DOCK10 DENND2D SRFBP1 FREM3 ARHGEF17

5.53e-05688749EFO_0000341
Diseasejuvenile myelomonocytic leukemia (is_implicated_in)

NF1 ARHGAP26

1.29e-047742DOID:0050458 (is_implicated_in)
DiseaseCarcinoma, Granular Cell

FAT4 ESR2 MKI67 PLCE1

2.11e-04116744C0205644
DiseaseAdenocarcinoma, Tubular

FAT4 ESR2 MKI67 PLCE1

2.11e-04116744C0205645
DiseaseAdenocarcinoma, Oxyphilic

FAT4 ESR2 MKI67 PLCE1

2.11e-04116744C0205642
DiseaseCarcinoma, Cribriform

FAT4 ESR2 MKI67 PLCE1

2.11e-04116744C0205643
DiseaseAdenocarcinoma, Basal Cell

FAT4 ESR2 MKI67 PLCE1

2.11e-04116744C0205641
DiseaseAdenocarcinoma

FAT4 ESR2 MKI67 PLCE1

2.11e-04116744C0001418
DiseaseFEV/FEC ratio

ARHGAP42 MTHFSD HMCN1 ARHGAP26 KIF1B AFF3 ARHGEF18 KDM7A DENND2D SRFBP1 ARHGEF17

2.34e-0412287411EFO_0004713
Diseasevital capacity

SH3TC2 ZFAT HMCN1 DNLZ MAPT RBBP8 MYH7B ARHGAP26 AFF3 PCGF5 PLCE1

2.47e-0412367411EFO_0004312
Diseasedilated cardiomyopathy 1S (implicated_via_orthology)

MYH13 MYH7B

2.76e-0410742DOID:0110454 (implicated_via_orthology)
Diseaseautosomal dominant hyaline body myopathy (implicated_via_orthology)

MYH13 MYH7B

2.76e-0410742DOID:0111269 (implicated_via_orthology)
Diseasecongenital myopathy 6 (implicated_via_orthology)

MYH13 MYH7B

2.76e-0410742DOID:0080719 (implicated_via_orthology)
Diseasedistal arthrogryposis type 2B3 (implicated_via_orthology)

MYH13 MYH7B

2.76e-0410742DOID:0111602 (implicated_via_orthology)
Diseaseinclusion body myositis (implicated_via_orthology)

MYH13 MYH7B

2.76e-0410742DOID:3429 (implicated_via_orthology)
Diseasedistal arthrogryposis type 2A (implicated_via_orthology)

MYH13 MYH7B

2.76e-0410742DOID:0111605 (implicated_via_orthology)
Diseasefamilial hypertrophic cardiomyopathy (implicated_via_orthology)

MYH13 MYH7B

2.76e-0410742DOID:0080326 (implicated_via_orthology)
Diseasedistal arthrogryposis type 1 (implicated_via_orthology)

MYH13 MYH7B

2.76e-0410742DOID:0111596 (implicated_via_orthology)
Diseasedistal myopathy (implicated_via_orthology)

MYH13 MYH7B

4.03e-0412742DOID:11720 (implicated_via_orthology)
Diseasemyotonia congenita (implicated_via_orthology)

MYH13 MYH7B

4.03e-0412742DOID:2106 (implicated_via_orthology)
DiseaseOligospermia

PIWIL4 BRWD1

4.03e-0412742C0028960
Diseaserestrictive cardiomyopathy (implicated_via_orthology)

MYH13 MYH7B

4.75e-0413742DOID:397 (implicated_via_orthology)
DiseaseBenign tumor of pancreas

BRCA2 RBBP8

4.75e-0413742C0347284
Diseasebreast cancer (is_implicated_in)

MCPH1 BRCA2 ESR2 MKI67

5.60e-04150744DOID:1612 (is_implicated_in)
Diseaseglycerate measurement

HMCN1 LZTFL1

6.38e-0415742EFO_0021029
DiseaseRASopathy

NF1 ARHGAP26

6.38e-0415742cv:C5555857
Diseasedistal arthrogryposis (implicated_via_orthology)

MYH13 MYH7B

6.38e-0415742DOID:0050646 (implicated_via_orthology)
DiseasePheochromocytoma, Extra-Adrenal

NF1 KIF1B

7.28e-0416742C1257877
Diseaseprotein C measurement

MYH7B BAZ1B

8.24e-0417742EFO_0004633
DiseaseQRS duration

ARHGAP42 FAT4 HMCN1 MYH7B OBSL1

9.26e-04298745EFO_0005055
Diseasehematocrit

MAPT ARHGAP26 ESR2 KIF1B AFF3 ZC3HC1 PFKL PCGF5 BAHCC1

9.43e-041011749EFO_0004348
DiseasePancreatic carcinoma

BRCA2 RBBP8

1.03e-0319742C0235974
DiseaseJuvenile Myelomonocytic Leukemia

NF1 ARHGAP26

1.03e-0319742C0349639
DiseasePheochromocytoma

NF1 KIF1B

1.03e-0319742C0031511
Diseaseeosinophil count

SH3TC2 ZFAT MAPT RBBP8 ARHGAP26 PARP8 LZTFL1 CCDC18 ARHGEF18 ZC3HC1 BAHCC1

1.16e-0314887411EFO_0004842
Diseasein situ carcinoma (is_marker_for)

ESR2 MKI67

1.26e-0321742DOID:8719 (is_marker_for)
Diseasetestosterone measurement

UBR1 NF1 HMCN1 MAPT ARHGAP26 ESR2 BAZ1B ZC3HC1 DENND2D BRWD1

1.27e-0312757410EFO_0004908
DiseasePrimary microcephaly

MCPH1 RBBP8

1.39e-0322742C0431350
DiseaseHereditary Paraganglioma-Pheochromocytoma Syndrome

NF1 KIF1B

1.52e-0323742C1708353
DiseaseHbA1c measurement

ZFAT DNLZ BAZ1B MAST1 DENND2D PFKL FREM3

1.52e-03675747EFO_0004541
DiseaseCoronary heart disease

ESR2 ZC3HC1

1.65e-0324742C0010068
DiseaseNeoplasm of the genitourinary tract

BRCA2 BCL10

1.65e-0324742cv:C0042065
DiseaseCerebral Astrocytoma

NF1 ESR2

1.79e-0325742C0750935
DiseaseIntracranial Astrocytoma

NF1 ESR2

1.79e-0325742C0750936
DiseasePilocytic Astrocytoma

NF1 ESR2

1.79e-0325742C0334583
DiseaseAstrocytoma

NF1 ESR2

1.79e-0325742C0004114
DiseaseJuvenile Pilocytic Astrocytoma

NF1 ESR2

1.79e-0325742C0280783
DiseaseDiffuse Astrocytoma

NF1 ESR2

1.79e-0325742C0280785
DiseaseGrade I Astrocytoma

NF1 ESR2

1.79e-0325742C1704230
Diseaseresponse to interferon

ARHGAP26 PLCE1

1.79e-0325742EFO_0007859
Diseasebreast cancer (implicated_via_orthology)

BRCA2 ESR2

1.79e-0325742DOID:1612 (implicated_via_orthology)
DiseaseSubependymal Giant Cell Astrocytoma

NF1 ESR2

1.79e-0325742C0205768
DiseaseMixed oligoastrocytoma

NF1 ESR2

1.79e-0325742C0547065
DiseaseChildhood Cerebral Astrocytoma

NF1 ESR2

1.79e-0325742C0338070
Diseasemyocardial infarction

ARHGAP42 ANKRD31 ARHGAP26 ZC3HC1 SRFBP1

1.88e-03350745EFO_0000612
DiseaseGemistocytic astrocytoma

NF1 ESR2

1.94e-0326742C0334581
DiseaseProtoplasmic astrocytoma

NF1 ESR2

1.94e-0326742C0334580
DiseaseFibrillary Astrocytoma

NF1 ESR2

1.94e-0326742C0334582
DiseaseCalcium channel blocker use measurement

ARHGAP42 ARHGEF18 ZC3HC1 PLCE1

2.05e-03213744EFO_0009930
DiseaseAnaplastic astrocytoma

NF1 ESR2

2.09e-0327742C0334579
DiseaseDevelopmental Academic Disorder

NF1 MAPT

2.41e-0329742C1330966
DiseaseLearning Disorders

NF1 MAPT

2.41e-0329742C0023186
DiseaseLearning Disturbance

NF1 MAPT

2.41e-0329742C0751263
DiseaseAdult Learning Disorders

NF1 MAPT

2.41e-0329742C0751262
DiseaseLearning Disabilities

NF1 MAPT

2.41e-0329742C0751265
Diseaserespiratory failure, COVID-19

MAPT LZTFL1

2.41e-0329742EFO_0009686, MONDO_0100096
Diseaseatrial fibrillation

ZFAT MAPT ARHGAP26 ESR2 KIF1B

2.42e-03371745EFO_0000275

Protein segments in the cluster

PeptideGeneStartEntry
SHRKELRSSVTCEKR

AFF3

636

P51826
LRSSVTCEKRRTRGL

AFF3

641

P51826
ALLVSSSCRRTKKVS

BAHCC1

2046

Q9P281
TSVKRRLSCLRSRVT

ARHGEF18

256

Q6ZSZ5
IRSSKQKCRLRVSTD

GRAMD1C

441

Q8IYS0
NTCISRLEKTRSKSE

RBBP8

366

Q99708
KRSALSCVISKTARL

BAZ1B

491

Q9UIG0
SCLRRLAVSSVLKSR

FAT4

3816

Q6V0I7
CRKRTVVSKRGVAVS

CCDC77

11

Q9BR77
VCTTLKRKSGSLRRS

ARHGEF17

1316

Q96PE2
ACVLRRSSRLEKLKV

ANKRD31

381

Q8N7Z5
NSRTTTLLRVKCVKH

OBSL1

501

O75147
KLLRRTCSSTVKTDD

PARP8

316

Q8N3A8
RCSTRVTVGTIKKFL

PCGF5

166

Q86SE9
LSRSQKCIRKEGSSE

KDM7A

821

Q6ZMT4
ARSKRGLRLKTVDSC

LZTFL1

21

Q9NQ48
QLSCRSLSKKERTSI

MCPH1

441

Q8NEM0
RETLKRKVSGNRCAS

ESR2

121

Q92731
TIRSKLSRRCPSQSK

KIF1B

1801

O60333
DSSRLKCTSIAVSRK

HPS5

31

Q9UPZ3
LRTACERAKRTLSSS

HSPA2

266

P54652
TLTRAKASAEKLCRT

MYH7B

1286

A7E2Y1
ILCRIRGSSSEAKNK

OR4N2

221

Q8NGD1
RSKEGRRKALSTCAS

OR4Q2

226

P0C623
SCDRIKQSASGTKRR

PFKL

551

P17858
FLQRRSSRRKVCTKT

GAPT

46

Q8N292
SKSVQRVTRSVKRCA

MKI67

3216

P46013
RLLIKGNSASKTRLC

HAUS5

401

O94927
AKLRRTTNRILASSC

ODF1

106

Q14990
KTRSIRRRDSCLNSK

GTSE1

426

Q9NYZ3
TKSCRTSNRKSLILT

MAST1

26

Q9Y2H9
TSLSRTRRTIRKTCP

HMCN1

5406

Q96RW7
RAQSRSRECDITKGK

PPIG

541

Q13427
KRLARILSACVLSKR

PORCN

366

Q9H237
DIIRSKTCSRRVKIN

KCNB2

26

Q92953
SKRGVDQTCTRVISK

DOCK10

2156

Q96BY6
RLKRRCTTSLIKEQE

BRCA2

3381

P51587
KVCGTRSSKRISKLA

DNLZ

76

Q5SXM8
KCTKLRRSISASDLT

CCDC18

1346

Q5T9S5
SCRTSSRKRAGKLLD

BCL10

56

O95999
NGSLLATTCKDRKIR

CORO2A

191

Q92828
ACKTTATTSSKRIVR

REXO1L1P

256

Q8IX06
REPCKKRLTARSIST

CBX4

421

O00257
RRKSLLTRKVICKSD

GOLPH3

111

Q9H4A6
NGLSRKISRKRVCSS

BRWD1

1891

Q9NSI6
RITRRCAATAANKIK

BRWD1

1926

Q9NSI6
RAACSRTSISRTKLR

INO80D

426

Q53TQ3
KSLVGVTAACTVRKR

ERCC3

346

P19447
ERSFCKALTSKTNRR

DENND2D

406

Q9H6A0
ASLKSGATATRRCRL

FREM3

196

P0C091
RKSILKSRSRENSVC

URI1

406

O94763
RRSSVCRLSSREKIS

PPP1R12C

341

Q9BZL4
VVCSIRKSSRTLKKG

TNFRSF21

366

O75509
KSKKERSTLLVRRFC

PLCE1

316

Q9P212
SRRTRAICLSTGSRK

ARHGAP42

591

A6NI28
TKKLRSNIRRSTETG

RIMS3

76

Q9UJD0
SVILKSCTRRKTDSI

ARHGAP26

316

Q9UNA1
NTSSRLSVIVVRKKC

PIWIL4

721

Q7Z3Z4
TARSLRRSLTCIKES

SH3TC2

1016

Q8TF17
RSRSRKISALKACRI

SPATA31E1

111

Q6ZUB1
RVTSHSLSCRRKGIL

NUAK1

511

O60285
PLRKAKRARLCSSSS

ZC3HC1

396

Q86WB0
AVCRKKFVSSIRLRT

ZFAT

461

Q9P243
SVCSKSFNRRESLKR

ZNF865

381

P0CJ78
FIGKVRRTRKKESSC

SRFBP1

286

Q8NEF9
TKDILRKCATSQGVR

MTHFSD

106

Q2M296
KRLREKSCLIVATTS

UBR1

986

Q8IWV7
ALSKSKSNIERTCRT

MYH13

1241

Q9UKX3
SEEVRSRCSLKHRKS

NF1

2446

P21359
STRSSAKTLKNRPCL

MAPT

396

P10636
KIRLSRLFRTKSCNG

SOCS7

211

O14512
VREKLGSSCKISRDR

THUMPD3

56

Q9BV44
KECGKAFRISSSLRR

ZNF442

436

Q9H7R0
RIKTIKTSCGNITRT

ZNF687

331

Q8N1G0
IKDINTGRSCAVRSK

ZNF766

86

Q5HY98
RKKLTSSGCIDDATR

PPIP5K2

1086

O43314
KECRKAFSVSSSLRR

ZNF891

491

A8MT65
RKGQKRLVLSESCSR

ZMYM3

1036

Q14202
LRKQCTRVTTLTGKK

DUSP19

16

Q8WTR2