Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionDNA-binding transcription factor activity, RNA polymerase II-specific

ZIK1 KLF1 ZNF732 ZNF718 ZNF358 ZNF436 ZNF722 ZNF735 ZNF790 ZSCAN18 GLIS3 ZNF217 ZNF841 ZNF446 NOTCH1

3.02e-0514126415GO:0000981
GeneOntologyMolecularFunctioncis-regulatory region sequence-specific DNA binding

ZIK1 KLF1 ZNF732 ZNF718 ZNF358 ZNF722 ZNF735 ZNF790 ZSCAN18 GLIS3 ZNF217 ZNF841 ZNF446 NOTCH1

3.95e-0512716414GO:0000987
GeneOntologyMolecularFunctionRNA polymerase II cis-regulatory region sequence-specific DNA binding

ZIK1 KLF1 ZNF732 ZNF718 ZNF358 ZNF722 ZNF735 ZNF790 ZSCAN18 GLIS3 ZNF217 ZNF841 ZNF446

1.33e-0412446413GO:0000978
GeneOntologyMolecularFunctionRNA polymerase II transcription regulatory region sequence-specific DNA binding

ZIK1 KLF1 ZNF732 ZNF718 ZNF358 ZNF436 ZNF722 ZNF735 ZNF790 ZSCAN18 GLIS3 ZNF217 ZNF841 ZNF446

1.74e-0414596414GO:0000977
GeneOntologyMolecularFunctionserine-type peptidase activity

RELN PRSS12 MMP2 F2 F9

5.29e-04207645GO:0008236
GeneOntologyMolecularFunctionserine hydrolase activity

RELN PRSS12 MMP2 F2 F9

5.90e-04212645GO:0017171
GeneOntologyMolecularFunctionpeptidase activity

RELN MMEL1 ADAMTS6 PRSS12 USP32 MMP2 F2 F9

1.11e-03654648GO:0008233
GeneOntologyMolecularFunctionmonoacylglycerol lipase activity

PNLIPRP2 ABHD12B

1.18e-0316642GO:0047372
GeneOntologyCellularComponentextracellular matrix

COL6A3 RELN ADAMTS6 PTPRZ1 LAMA1 SEMA3B LTBP2 MMP2 F2 F9

2.84e-056566410GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

COL6A3 RELN ADAMTS6 PTPRZ1 LAMA1 SEMA3B LTBP2 MMP2 F2 F9

2.91e-056586410GO:0030312
GeneOntologyCellularComponentcollagen-containing extracellular matrix

COL6A3 RELN PTPRZ1 LAMA1 SEMA3B LTBP2 MMP2 F2 F9

3.22e-05530649GO:0062023
Domain-

PRDM9 ZIK1 KLF1 ZNF732 ZNF718 ZNF358 ZNF436 ZNF735 ZNF790 ZSCAN18 GLIS3 ZNF217 ZNF841 ZFPM1 ZNF446 ZXDB

5.83e-1067963163.30.160.60
DomainZnf_C2H2/integrase_DNA-bd

PRDM9 ZIK1 KLF1 ZNF732 ZNF718 ZNF358 ZNF436 ZNF735 ZNF790 ZSCAN18 GLIS3 ZNF217 ZNF841 ZFPM1 ZNF446 ZXDB

8.00e-106946316IPR013087
DomainZINC_FINGER_C2H2_2

PRDM9 ZIK1 KLF1 ZNF732 ZNF718 ZNF358 ZNF436 ZNF735 ZNF790 ZSCAN18 GLIS3 ZNF217 ZNF841 ZFPM1 ZNF446 ZXDB

3.91e-097756316PS50157
DomainZINC_FINGER_C2H2_1

PRDM9 ZIK1 KLF1 ZNF732 ZNF718 ZNF358 ZNF436 ZNF735 ZNF790 ZSCAN18 GLIS3 ZNF217 ZNF841 ZFPM1 ZNF446 ZXDB

4.06e-097776316PS00028
DomainZnf_C2H2-like

PRDM9 ZIK1 KLF1 ZNF732 ZNF718 ZNF358 ZNF436 ZNF735 ZNF790 ZSCAN18 GLIS3 ZNF217 ZNF841 ZFPM1 ZNF446 ZXDB

5.72e-097966316IPR015880
DomainZnf_C2H2

PRDM9 ZIK1 KLF1 ZNF732 ZNF718 ZNF358 ZNF436 ZNF735 ZNF790 ZSCAN18 GLIS3 ZNF217 ZNF841 ZFPM1 ZNF446 ZXDB

6.71e-098056316IPR007087
Domainzf-C2H2

PRDM9 ZIK1 KLF1 ZNF732 ZNF718 ZNF358 ZNF436 ZNF735 ZNF790 GLIS3 ZNF217 ZNF841 ZFPM1 ZNF446 ZXDB

6.98e-096936315PF00096
DomainZnF_C2H2

PRDM9 ZIK1 KLF1 ZNF732 ZNF718 ZNF358 ZNF436 ZNF735 ZNF790 ZSCAN18 GLIS3 ZNF217 ZNF841 ZFPM1 ZNF446 ZXDB

7.07e-098086316SM00355
DomainEGF_extracell

ITGBL1 RELN JAG1 LTBP2 NOTCH1

1.76e-0660635IPR013111
DomainEGF_2

ITGBL1 RELN JAG1 LTBP2 NOTCH1

1.76e-0660635PF07974
DomainKringle-like

PRSS12 MRC2 MMP2 F2

3.94e-0632634IPR013806
DomainEGF

ITGBL1 RELN JAG1 LAMA1 LTBP2 F9 NOTCH1

1.39e-05235637SM00181
DomainEGF-like_dom

ITGBL1 RELN JAG1 LAMA1 LTBP2 F9 NOTCH1

2.02e-05249637IPR000742
DomainEGF_1

ITGBL1 RELN JAG1 LAMA1 LTBP2 F9 NOTCH1

2.35e-05255637PS00022
DomainKRAB

PRDM9 ZIK1 ZNF732 ZNF718 ZNF436 ZNF735 ZNF790 ZNF446

2.60e-05358638PF01352
DomainEGF_2

ITGBL1 RELN JAG1 LAMA1 LTBP2 F9 NOTCH1

3.00e-05265637PS01186
DomainKRAB

PRDM9 ZIK1 ZNF732 ZNF718 ZNF436 ZNF735 ZNF790 ZNF446

3.23e-05369638SM00349
DomainKRAB

PRDM9 ZIK1 ZNF732 ZNF718 ZNF436 ZNF735 ZNF790 ZNF446

3.29e-05370638IPR001909
Domainzf-C2H2_6

PRDM9 ZNF732 ZNF718 ZNF358 ZNF735 ZNF790 ZNF841

8.77e-05314637PF13912
DomainKRAB

ZIK1 ZNF732 ZNF718 ZNF436 ZNF735 ZNF790 ZNF446

1.97e-04358637PS50805
DomainEGF-like_CS

RELN JAG1 LAMA1 LTBP2 F9 NOTCH1

2.45e-04261636IPR013032
DomainEGF_Ca-bd_CS

JAG1 LTBP2 F9 NOTCH1

3.22e-0497634IPR018097
DomainEGF_CA

JAG1 LTBP2 F9 NOTCH1

3.48e-0499634PS01187
DomainASX_HYDROXYL

JAG1 LTBP2 F9 NOTCH1

3.62e-04100634PS00010
DomainEGF-type_Asp/Asn_hydroxyl_site

JAG1 LTBP2 F9 NOTCH1

4.51e-04106634IPR000152
Domain-

KBTBD3 KLHDC7A KLHL14

5.68e-04486332.120.10.80
Domain-

F2 F9

7.23e-04126324.10.740.10
DomainCoagulation_fac_subgr_Gla_dom

F2 F9

7.23e-0412632IPR017857
DomainEGF_CA

JAG1 LTBP2 F9 NOTCH1

7.67e-04122634SM00179
DomainEGF-like_Ca-bd_dom

JAG1 LTBP2 F9 NOTCH1

8.15e-04124634IPR001881
DomainKelch-typ_b-propeller

KBTBD3 KLHDC7A KLHL14

8.47e-0455633IPR015915
DomainNCD3G

TAS1R1 GRM2

8.53e-0413632PF07562
DomainGPCR_3_9-Cys_dom

TAS1R1 GRM2

8.53e-0413632IPR011500
Domain-

MRC2 MMP2

8.53e-04136322.10.10.10
DomainEGF

JAG1 LTBP2 F9 NOTCH1

8.65e-04126634PF00008
DomainKelch

KBTBD3 KLHDC7A KLHL14

9.89e-0458633SM00612
DomainFN_type2_col-bd

MRC2 MMP2

9.93e-0414632IPR000562
DomainFN2_2

MRC2 MMP2

9.93e-0414632PS51092
DomainGla

F2 F9

9.93e-0414632PF00594
Domainfn2

MRC2 MMP2

9.93e-0414632PF00040
DomainGLA

F2 F9

9.93e-0414632SM00069
DomainFN2_1

MRC2 MMP2

9.93e-0414632PS00023
DomainGPCR_3_CS

TAS1R1 GRM2

9.93e-0414632IPR017979
DomainFN2

MRC2 MMP2

9.93e-0414632SM00059
DomainGLA_1

F2 F9

9.93e-0414632PS00011
DomainGLA_domain

F2 F9

9.93e-0414632IPR000294
DomainGLA_2

F2 F9

9.93e-0414632PS50998
DomainEGF_3

RELN JAG1 LTBP2 F9 NOTCH1

1.17e-03235635PS50026
DomainKringle

PRSS12 F2

1.47e-0317632IPR000001
DomainKringle_CS

PRSS12 F2

1.47e-0317632IPR018056
DomainKRINGLE_2

PRSS12 F2

1.47e-0317632PS50070
DomainKringle

PRSS12 F2

1.47e-0317632PF00051
DomainKRINGLE_1

PRSS12 F2

1.47e-0317632PS00021
DomainKR

PRSS12 F2

1.47e-0317632SM00130
DomainKelch_1

KBTBD3 KLHDC7A KLHL14

1.70e-0370633PF01344
DomainKelch_1

KBTBD3 KLHDC7A KLHL14

1.70e-0370633IPR006652
DomainGrowth_fac_rcpt_

JAG1 LAMA1 LTBP2 NOTCH1

1.90e-03156634IPR009030
DomainGPCR_3

TAS1R1 GRM2

2.26e-0321632IPR000337
Domain7tm_3

TAS1R1 GRM2

2.48e-0322632PF00003
DomainG_PROTEIN_RECEP_F3_2

TAS1R1 GRM2

2.48e-0322632PS00980
DomainG_PROTEIN_RECEP_F3_3

TAS1R1 GRM2

2.48e-0322632PS00981
DomainG_PROTEIN_RECEP_F3_1

TAS1R1 GRM2

2.48e-0322632PS00979
DomainG_PROTEIN_RECEP_F3_4

TAS1R1 GRM2

2.48e-0322632PS50259
DomainGPCR_3_C

TAS1R1 GRM2

2.48e-0322632IPR017978
DomainMetalloPept_cat_dom

MMEL1 ADAMTS6 MMP2

2.59e-0381633IPR024079
Domain-

MMEL1 ADAMTS6 MMP2

2.59e-03816333.40.390.10
DomainC2H2_Znf_fam

ZSCAN18 ZNF446

2.95e-0324632IPR027775
DomainEGF_CA

JAG1 LTBP2 NOTCH1

3.07e-0386633PF07645
DomainTRYPSIN_SER

PRSS12 F2 F9

3.49e-0390633IPR033116
DomainhEGF

JAG1 NOTCH1

4.00e-0328632PF12661
DomainZINC_PROTEASE

MMEL1 ADAMTS6 MMP2

4.43e-0398633PS00142
DomainTRYPSIN_HIS

PRSS12 F2 F9

5.09e-03103633IPR018114
DomainTRYPSIN_SER

PRSS12 F2 F9

5.51e-03106633PS00135
DomainTRYPSIN_HIS

PRSS12 F2 F9

5.66e-03107633PS00134
DomainPeptidase_S1A

PRSS12 F2 F9

6.58e-03113633IPR001314
PathwayREACTOME_DEFECTIVE_FACTOR_VIII_CAUSES_HEMOPHILIA_A

F2 F9

1.98e-047442M39000
PathwayREACTOME_SIGNALING_BY_NOTCH1_T_7_9_NOTCH1_M1580_K2555_TRANSLOCATION_MUTANT

JAG1 NOTCH1

1.98e-047442M27199
PathwayREACTOME_TRANSPORT_OF_GAMMA_CARBOXYLATED_PROTEIN_PRECURSORS_FROM_THE_ENDOPLASMIC_RETICULUM_TO_THE_GOLGI_APPARATUS

F2 F9

3.38e-049442MM14614
PathwayREACTOME_GAMMA_CARBOXYLATION_OF_PROTEIN_PRECURSORS

F2 F9

3.38e-049442MM14613
PathwayREACTOME_REMOVAL_OF_AMINOTERMINAL_PROPEPTIDES_FROM_GAMMA_CARBOXYLATED_PROTEINS

F2 F9

4.22e-0410442M26977
PathwayREACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS

F2 F9

5.14e-0411442M12484
PathwayREACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS

F2 F9

5.14e-0411442MM14615
PathwayKEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00380

JAG1 NOTCH1

6.16e-0412442M47532
PathwayKEGG_MEDICUS_REFERENCE_NOTCH_SIGNALING_PATHWAY

JAG1 NOTCH1

7.27e-0413442M47423
PathwayWP_VITAMIN_K_METABOLISM_AND_ACTIVATION_OF_DEPENDENT_PROTEINS

F2 F9

7.27e-0413442M45518
PathwayWP_NEUROGENESIS_REGULATION_IN_THE_OLFACTORY_EPITHELIUM

RELN JAG1 NOTCH1

7.38e-0457443M48326
PathwayREACTOME_GAMMA_CARBOXYLATION_HYPUSINYLATION_HYDROXYLATION_AND_ARYLSULFATASE_ACTIVATION

OGFOD1 F2 F9

7.38e-0457443MM14634
PathwayBIOCARTA_PLATELETAPP_PATHWAY

F2 F9

8.46e-0414442MM1458
PathwayBIOCARTA_PLATELETAPP_PATHWAY

F2 F9

8.46e-0414442M6487
PathwayREACTOME_RUNX3_REGULATES_NOTCH_SIGNALING

JAG1 NOTCH1

8.46e-0414442M27808
PathwayREACTOME_GAMMA_CARBOXYLATION_HYPUSINYLATION_HYDROXYLATION_AND_ARYLSULFATASE_ACTIVATION

OGFOD1 F2 F9

9.00e-0461443M26993
PathwayREACTOME_SIGNALING_BY_NOTCH1_HD_DOMAIN_MUTANTS_IN_CANCER

JAG1 NOTCH1

9.74e-0415442M27202
PathwayREACTOME_DEFECTS_OF_CONTACT_ACTIVATION_SYSTEM_CAS_AND_KALLIKREIN_KININ_SYSTEM_KKS

F2 F9

1.11e-0316442M38996
PathwayKEGG_MEDICUS_VARIANT_NOTCH_OVEREXPRESSION_TO_NOTCH_SIGNALING_PATHWAY

JAG1 NOTCH1

1.11e-0316442M47424
PathwayREACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS

ADAMTS6 NOTCH1 LARGE1

1.23e-0368443M27303
PathwayWP_AMPLIFICATION_AND_EXPANSION_OF_ONCOGENIC_PATHWAYS_AS_METASTATIC_TRAITS

JAG1 NOTCH1

1.26e-0317442M39443
PathwayWP_NOTCH1_REGULATION_OF_ENDOTHELIAL_CELL_CALCIFICATION

JAG1 NOTCH1

1.26e-0317442M39389
PathwayREACTOME_DISEASES_OF_HEMOSTASIS

F2 F9

1.57e-0319442M48230
PathwayREACTOME_PROTEIN_HYDROXYLATION

OGFOD1 F9

1.75e-0320442M48009
PathwayWP_BLOOD_CLOTTING_CASCADE

F2 F9

2.11e-0322442M39480
PathwayWP_DELTANOTCH_SIGNALING_PATHWAY

JAG1 ZFPM1 NOTCH1

2.12e-0382443MM15922
PathwayKEGG_ECM_RECEPTOR_INTERACTION

COL6A3 RELN LAMA1

2.27e-0384443M7098
PathwayBIOCARTA_INTRINSIC_PATHWAY

F2 F9

2.31e-0323442M15997
PathwayREACTOME_INTRINSIC_PATHWAY_OF_FIBRIN_CLOT_FORMATION

F2 F9

2.31e-0323442M14766
PathwayBIOCARTA_INTRINSIC_PATHWAY

F2 F9

2.31e-0323442MM1427
PathwayWP_BLOOD_CLOTTING_CASCADE

F2 F9

2.31e-0323442MM15936
PathwayREACTOME_INTRINSIC_PATHWAY_OF_FIBRIN_CLOT_FORMATION

F2 F9

2.31e-0323442MM14557
PathwayREACTOME_RNA_POLYMERASE_II_TRANSCRIPTION

ITGBL1 ZIK1 ZNF732 ZNF718 ZNF436 JAG1 ZNF735 ZNF790 ZFPM1 ZNF446 NOTCH1

2.91e-0313874411M734
PathwayWP_CANONICAL_AND_NONCANONICAL_NOTCH_SIGNALING

JAG1 NOTCH1

3.18e-0327442M39545
Pubmed

Notch2, but not Notch1, is required for proximal fate acquisition in the mammalian nephron.

JAG1 LAMA1 NOTCH1

3.43e-061665317229764
Pubmed

In-vitro evaluation of anti-factor IXa aptamer on thrombin generation, clotting time, and viscoelastometry.

F2 F9

3.44e-06265219404534
Pubmed

Molecular basis for Jagged-1/Serrate ligand recognition by the Notch receptor.

JAG1 NOTCH1

3.44e-06265223339193
Pubmed

A mutation in EGF repeat-8 of Notch discriminates between Serrate/Jagged and Delta family ligands.

JAG1 NOTCH1

3.44e-06265223197537
Pubmed

Suppression of renal cell carcinoma growth by inhibition of Notch signaling in vitro and in vivo.

JAG1 NOTCH1

3.44e-06265218079963
Pubmed

Jagged1-Notch1 Signaling Pathway Induces M1 Microglia to Disrupt the Barrier Function of Retinal Microvascular Endothelial Cells.

JAG1 NOTCH1

3.44e-06265238783634
Pubmed

A conserved face of the Jagged/Serrate DSL domain is involved in Notch trans-activation and cis-inhibition.

JAG1 NOTCH1

3.44e-06265218660822
Pubmed

Notch1 ligand signaling pathway activated in cervical cancer: poor prognosis with high-level JAG1/Notch1.

JAG1 NOTCH1

3.44e-06265225842263
Pubmed

NOTCH reprograms mitochondrial metabolism for proinflammatory macrophage activation.

LYZ NOTCH1

3.44e-06265225798621
Pubmed

Bronchial Epithelial Cells Promote the Differentiation of Th2 Lymphocytes in Airway Microenvironment through Jagged/Notch-1 Signaling after RSV Infection.

JAG1 NOTCH1

3.44e-06265230943513
Pubmed

Prognostic significance of Notch signalling molecules and their involvement in the invasiveness of endometrial carcinoma cells.

JAG1 NOTCH1

3.44e-06265222348356
Pubmed

Jagged1 and Notch1 help edit M cell patterning in Peyer's patch follicle epithelium.

JAG1 NOTCH1

3.44e-06265222504165
Pubmed

Absence of Notch1 in murine myeloid cells attenuates the development of experimental autoimmune encephalomyelitis by affecting Th1 and Th17 priming.

LYZ NOTCH1

3.44e-06265228762472
Pubmed

Human Cytomegalovirus Infection Dysregulates the Localization and Stability of NICD1 and Jag1 in Neural Progenitor Cells.

JAG1 NOTCH1

3.44e-06265225903338
Pubmed

Differential actions of the endocytic collagen receptor uPARAP/Endo180 and the collagenase MMP-2 in bone homeostasis.

MRC2 MMP2

3.44e-06265223940733
Pubmed

Jagged1-dependent Notch signaling is dispensable for hematopoietic stem cell self-renewal and differentiation.

JAG1 NOTCH1

3.44e-06265215550486
Pubmed

Association of high levels of Jagged-1 and Notch-1 expression with poor prognosis in head and neck cancer.

JAG1 NOTCH1

3.44e-06265220517681
Pubmed

Astrocytes Regulate Angiogenesis Through the Jagged1-Mediated Notch1 Pathway After Status Epilepticus.

JAG1 NOTCH1

3.44e-06265226507745
Pubmed

Jagged1 signals in the postnatal subventricular zone are required for neural stem cell self-renewal.

JAG1 NOTCH1

3.44e-06265216163386
Pubmed

Cleavage of human corneal type VI collagen alpha 3 chain by matrix metalloproteinase-2.

COL6A3 MMP2

3.44e-0626528862926
Pubmed

Up-regulated expression of Notch1 and Jagged1 in human colon adenocarcinoma.

JAG1 NOTCH1

3.44e-06265221145176
Pubmed

Studies on sporadic non-syndromic thoracic aortic aneurysms: 1. Deregulation of Jagged/Notch 1 homeostasis and selection of synthetic/secretor phenotype smooth muscle cells.

JAG1 NOTCH1

3.44e-06265229708032
Pubmed

The Notch ligand Jagged-1 is able to induce maturation of monocyte-derived human dendritic cells.

JAG1 NOTCH1

3.44e-06265212370358
Pubmed

Blocking the NOTCH pathway inhibits vascular inflammation in large-vessel vasculitis.

JAG1 NOTCH1

3.44e-06265221220737
Pubmed

JAG1-Mediated Notch Signaling Regulates Secretory Cell Differentiation of the Human Airway Epithelium.

JAG1 NOTCH1

3.44e-06265227216293
Pubmed

Multiple sclerosis: re-expression of a developmental pathway that restricts oligodendrocyte maturation.

JAG1 NOTCH1

3.44e-06265212357247
Pubmed

Activated Notch1 signaling promotes tumor cell proliferation and survival in Hodgkin and anaplastic large cell lymphoma.

JAG1 NOTCH1

3.44e-06265211964309
Pubmed

Jagged1-induced Notch activation contributes to the acquisition of bortezomib resistance in myeloma cells.

JAG1 NOTCH1

3.44e-06265229242532
Pubmed

Endothelial cells provide a notch-dependent pro-tumoral niche for enhancing breast cancer survival, stemness and pro-metastatic properties.

JAG1 NOTCH1

3.44e-06265225380486
Pubmed

Activating Notch signaling post-SCI modulates angiogenesis in penumbral vascular beds but does not improve hindlimb locomotor recovery.

JAG1 NOTCH1

3.44e-06265221156172
Pubmed

NOTCH1 mutations in individuals with left ventricular outflow tract malformations reduce ligand-induced signaling.

JAG1 NOTCH1

3.44e-06265218593716
Pubmed

Stroma-induced Jagged1 expression drives PC3 prostate cancer cell migration; disparate effects of RIP-generated proteolytic fragments on cell behaviour and Notch signaling.

JAG1 NOTCH1

3.44e-06265226921446
Pubmed

The significance of circulating factor IXa in blood.

F2 F9

3.44e-06265215039440
Pubmed

Notch signaling through Jagged-1 is necessary to initiate chondrogenesis in human bone marrow stromal cells but must be switched off to complete chondrogenesis.

JAG1 NOTCH1

3.44e-06265218192230
Pubmed

Targeting Notch1-YAP Circuit Reprograms Macrophage Polarization and Alleviates Acute Liver Injury in Mice.

LYZ NOTCH1

3.44e-06265236706917
Pubmed

Spatially restricted JAG1-Notch signaling in human thymus provides suitable DC developmental niches.

JAG1 NOTCH1

3.44e-06265228947612
Pubmed

Epidermal stem cells (ESCs) accelerate diabetic wound healing via the Notch signalling pathway.

JAG1 NOTCH1

3.44e-06265227129289
Pubmed

Immunohistochemical analysis of NOTCH1 and JAGGED1 expression in multiple myeloma and monoclonal gammopathy of undetermined significance.

JAG1 NOTCH1

3.44e-06265220800871
Pubmed

Activation of an endothelial Notch1-Jagged1 circuit induces VCAM1 expression, an effect amplified by interleukin-1β.

JAG1 NOTCH1

3.44e-06265226646450
Pubmed

[Gene expression of Notch1 and Jagged1 in children with acute leukemia].

JAG1 NOTCH1

3.44e-06265222357466
Pubmed

JAG1 overexpression contributes to Notch1 signaling and the migration of HTLV-1-transformed ATL cells.

JAG1 NOTCH1

3.44e-06265230231940
Pubmed

Notch1 Regulates Hippocampal Plasticity Through Interaction with the Reelin Pathway, Glutamatergic Transmission and CREB Signaling.

RELN NOTCH1

3.44e-06265226635527
Pubmed

A study of the role of Notch1 and JAG1 gene methylation in development of breast cancer.

JAG1 NOTCH1

3.44e-06265226971121
Pubmed

Notch1 signaling and regulatory T cell function.

JAG1 NOTCH1

3.44e-06265218292500
Pubmed

Jagged1 intracellular domain-mediated inhibition of Notch1 signalling regulates cardiac homeostasis in the postnatal heart.

JAG1 NOTCH1

3.44e-06265226249804
Pubmed

Mesenchymal stromal cells affect cardiomyocyte growth through juxtacrine Notch-1/Jagged-1 signaling and paracrine mechanisms: clues for cardiac regeneration.

JAG1 NOTCH1

3.44e-06265221712044
Pubmed

Immunohistochemical localization of Notch signaling molecules in ameloblastomas.

JAG1 NOTCH1

3.44e-06265221810559
Pubmed

Notch is required for the formation of all nephron segments and primes nephron progenitors for differentiation.

JAG1 LAMA1 NOTCH1

4.98e-061865329113990
Pubmed

Evolution of Cortical Neurogenesis in Amniotes Controlled by Robo Signaling Levels.

RELN JAG1 NOTCH1

6.94e-062065329961574
Pubmed

Combined loss of Hey1 and HeyL causes congenital heart defects because of impaired epithelial to mesenchymal transition.

JAG1 MMP2 NOTCH1

8.09e-062165317303760
Pubmed

The N-Myc-DLL3 cascade is suppressed by the ubiquitin ligase Huwe1 to inhibit proliferation and promote neurogenesis in the developing brain.

RELN JAG1 NOTCH1

8.09e-062165319686682
Pubmed

Myeloid p53 regulates macrophage polarization and venous thrombus resolution by inflammatory vascular remodeling in mice.

MMP2 LYZ

1.03e-05365228320710
Pubmed

Jagged1-selective notch signaling induces smooth muscle differentiation via a RBP-Jkappa-dependent pathway.

JAG1 NOTCH1

1.03e-05365216867989
Pubmed

Activation of Notch signal pathway is associated with a poorer prognosis in acute myeloid leukemia.

JAG1 NOTCH1

1.03e-05365220812035
Pubmed

Both Notch1 and its ligands in B cells promote antibody production.

JAG1 NOTCH1

1.03e-05365228863329
Pubmed

Expression of Notch1, Jagged1 and beta-catenin and their clinicopathological significance in hepatocellular carcinoma.

JAG1 NOTCH1

1.03e-05365219728763
Pubmed

Notch1, Jagged1, and HES5 are abundantly expressed in osteoarthritis.

JAG1 NOTCH1

1.03e-05365218354251
Pubmed

Noncanonical Notch signaling modulates cytokine responses of dendritic cells to inflammatory stimuli.

JAG1 NOTCH1

1.03e-05365222753939
Pubmed

Cancer stem cell and embryonic development-associated molecules contribute to prognostic significance in ovarian cancer.

JAG1 NOTCH1

1.03e-05365222080880
Pubmed

Reelin and Notch1 cooperate in the development of the dentate gyrus.

RELN NOTCH1

1.03e-05365219571148
Pubmed

A three-molecule score based on Notch pathway predicts poor prognosis in non-metastasis clear cell renal cell carcinoma.

JAG1 NOTCH1

1.03e-05365227612417
Pubmed

Overexpression of miR-34c inhibits high glucose-induced apoptosis in podocytes by targeting Notch signaling pathways.

JAG1 NOTCH1

1.03e-05365226191142
Pubmed

The Interplay of MicroRNA-34a, LGR4, EMT-Associated Factors, and MMP2 in Regulating Uveal Melanoma Cells.

LGR4 MMP2

1.03e-05365231661551
Pubmed

Notch activation results in phenotypic and functional changes consistent with endothelial-to-mesenchymal transformation.

JAG1 NOTCH1

1.03e-05365214988227
Pubmed

The life cycle of coagulation factor VIII in view of its structure and function.

F2 F9

1.03e-0536529834200
Pubmed

Collagen I and thrombin activate MMP-2 by MMP-14-dependent and -independent pathways: implications for airway smooth muscle migration.

MMP2 F2

1.03e-05365217189319
Pubmed

Inhibition of HER2 Increases JAGGED1-dependent Breast Cancer Stem Cells: Role for Membrane JAGGED1.

JAG1 NOTCH1

1.03e-05365229895705
Pubmed

Jagged1 is necessary for postnatal and adult neurogenesis in the dentate gyrus.

JAG1 NOTCH1

1.03e-05365224530424
Pubmed

Notch signaling represses myocardin-induced smooth muscle cell differentiation.

JAG1 NOTCH1

1.03e-05365215634680
Pubmed

Olfactory Sensory Neurons Control Dendritic Complexity of Mitral Cells via Notch Signaling.

JAG1 NOTCH1

1.03e-05365228027303
Pubmed

Notch pathway activation enhances cardiosphere in vitro expansion.

JAG1 NOTCH1

1.03e-05365230138533
Pubmed

Notch exhibits ligand bias and maneuvers stage-specific steering of neural differentiation in embryonic stem cells.

JAG1 NOTCH1

1.03e-05365220154142
Pubmed

Inhibition of Rspo-Lgr4 Facilitates Checkpoint Blockade Therapy by Switching Macrophage Polarization.

LGR4 LYZ

1.03e-05365229967265
Pubmed

Expression of Notch-1 and its ligands, Delta-like-1 and Jagged-1, is critical for glioma cell survival and proliferation.

JAG1 NOTCH1

1.03e-05365215781650
Pubmed

Jagged1-induced Notch signaling drives proliferation of multiple myeloma cells.

JAG1 NOTCH1

1.03e-05365214726396
Pubmed

Jagged1-Notch1-deployed tumor perivascular niche promotes breast cancer stem cell phenotype through Zeb1.

JAG1 NOTCH1

1.03e-05365233046710
Pubmed

Intracellular pathogen sensor NOD2 programs macrophages to trigger Notch1 activation.

JAG1 NOTCH1

1.03e-05365221156799
Pubmed

Polymorphisms in the Angiogenesis-Related Genes EFNB2, MMP2 and JAG1 Are Associated with Survival of Colorectal Cancer Patients.

JAG1 MMP2

1.03e-05365232751332
Pubmed

HIV-1 interaction with human mannose receptor (hMR) induces production of matrix metalloproteinase 2 (MMP-2) through hMR-mediated intracellular signaling in astrocytes.

MRC2 MMP2

1.03e-05365215955449
Pubmed

Epigenetic silencing of microRNA-199b-5p is associated with acquired chemoresistance via activation of JAG1-Notch1 signaling in ovarian cancer.

JAG1 NOTCH1

1.03e-05365224659709
Pubmed

Characterization of Notch Signalling Pathway Members in Normal Prostate, Prostatic Intraepithelial Neoplasia (PIN) and Prostatic Adenocarcinoma.

JAG1 NOTCH1

1.03e-05365226341090
Pubmed

Tissue factor deficiency increases alveolar hemorrhage and death in influenza A virus-infected mice.

LYZ F9

1.03e-05365226947929
Pubmed

Mouse large can modify complex N- and mucin O-glycans on alpha-dystroglycan to induce laminin binding.

LAMA1 LARGE1

1.03e-05365215788414
Pubmed

Immunohistochemical expression of Notch1, Jagged1, NF-κB and MMP-9 in colorectal cancer patients and the relationship to clinicopathological parameters.

JAG1 NOTCH1

1.03e-05365226406415
Pubmed

Unique patterns of Notch1, Notch4 and Jagged1 expression in ovarian vessels during folliculogenesis and corpus luteum formation.

JAG1 NOTCH1

1.03e-05365215939383
Pubmed

Spatial localization of the JAG1/Notch1/osteopontin cascade modulates extrahepatic metastasis in hepatocellular carcinoma.

JAG1 NOTCH1

1.03e-05365225176314
Pubmed

Reelin induces a radial glial phenotype in human neural progenitor cells by activation of Notch-1.

RELN NOTCH1

1.03e-05365218593473
Pubmed

[Expression of Notch1, MMP-2 and MMP-9 and their significance in glioma patients].

MMP2 NOTCH1

1.03e-05365222490851
Pubmed

Astrocyte-derived Jagged-1 mitigates deleterious Notch signaling in amyotrophic lateral sclerosis.

JAG1 NOTCH1

1.03e-05365230010003
Pubmed

Notch1 signaling pathway participates in cancer invasion by regulating MMPs in lingual squamous cell carcinoma.

MMP2 NOTCH1

1.03e-05365221993452
Pubmed

Papillomavirus-mediated neoplastic progression is associated with reciprocal changes in JAGGED1 and manic fringe expression linked to notch activation.

JAG1 NOTCH1

1.03e-05365215280477
Pubmed

Reelin regulates differentiation of neural stem cells by activation of notch signaling through Disabled-1 tyrosine phosphorylation.

RELN NOTCH1

1.03e-05365222394407
Pubmed

Molecular reconstruction and homology modelling of the catalytic domain of the common ancestor of the haemostatic vitamin-K-dependent serine proteinases.

F2 F9

1.03e-0536528707309
Pubmed

Regulatory mechanism of matrix metalloprotease-2 enzymatic activity by factor Xa and thrombin.

MMP2 F2

1.03e-05365219581306
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

UBR2 GLA SPOCK1 MRC2 LAMA1 SEMA3B LGR4 LTBP2 MMP2 SLC30A1 NOTCH1

1.29e-051201651135696571
Pubmed

Dbx1 controls the development of astrocytes of the intermediate spinal cord by modulating Notch signaling.

RELN JAG1 NOTCH1

1.39e-052565335815610
Pubmed

The structural role of radial glial endfeet in confining spinal motor neuron somata is controlled by the Reelin and Notch pathways.

RELN JAG1 NOTCH1

1.57e-052665323988635
Pubmed

Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.

COL6A3 RELN LAMA1 LTBP2 F2

1.97e-0517565528071719
Pubmed

Smooth muscle cell-specific Notch1 haploinsufficiency restricts the progression of abdominal aortic aneurysm by modulating CTGF expression.

LYZ NOTCH1

2.06e-05465228562688
Pubmed

miR-34a-5p Inhibits Cell Proliferation, Migration and Invasion Through Targeting JAG1/Notch1 Pathway in HPV-Infected Human Epidermal Keratinocytes.

JAG1 NOTCH1

2.06e-05465231781973
Cytoband4p16.3

ZNF732 ZNF718 LYAR

2.46e-04856534p16.3
Cytoband19q13.43

ZIK1 ZSCAN18 ZNF446

2.64e-048765319q13.43
Cytoband1p36

MMEL1 ZNF436

2.05e-03476521p36
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

PRDM9 ZIK1 KLF1 ZNF732 ZNF718 ZNF358 ZNF436 ZNF735 ZNF790 ZSCAN18 GLIS3 ZNF217 ZNF841 ZFPM1 ZNF446 ZXDB

4.52e-11718501628
GeneFamilyGla domain containing

F2 F9

5.73e-04135021250
GeneFamilyZinc fingers C2HC-type|PHD finger proteins|Lysine acetyltransferases

ZFPM1 LYAR

8.77e-041650266
CoexpressionFOROUTAN_INTEGRATED_TGFB_EMT_UP

COL6A3 ADAMTS6 SPOCK1 MRC2 JAG1 MMP2

4.05e-07120626M42505
CoexpressionBOQUEST_STEM_CELL_UP

COL6A3 ITGBL1 SPOCK1 MRC2 SUSD5 LTBP2 MMP2

2.76e-06261627M1834
CoexpressionNABA_MATRISOME

COL6A3 RELN ADAMTS6 SPOCK1 PRSS12 LAMA1 SEMA3B OGFOD1 LTBP2 MMP2 F2 F9

3.59e-0610086212MM17056
CoexpressionNABA_MATRISOME

COL6A3 RELN ADAMTS6 SPOCK1 PRSS12 LAMA1 SEMA3B OGFOD1 LTBP2 MMP2 F2 F9

4.30e-0610266212M5889
CoexpressionFOROUTAN_TGFB_EMT_UP

COL6A3 ADAMTS6 SPOCK1 MRC2 JAG1 MMP2

6.25e-06192626M42501
CoexpressionGSE2405_0H_VS_3H_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_UP

COL6A3 PTPRZ1 LGR4 LTBP2 MMP2 LARGE1

7.89e-06200626M6212
CoexpressionCHARAFE_BREAST_CANCER_LUMINAL_VS_MESENCHYMAL_DN

COL6A3 PRSS12 MRC2 JAG1 GLIS3 LTBP2 MMP2 SYDE1

1.35e-05465628M9192
CoexpressionANASTASSIOU_MULTICANCER_INVASIVENESS_SIGNATURE

COL6A3 ITGBL1 SPOCK1 MMP2

1.62e-0564624M2572
CoexpressionNABA_ECM_REGULATORS

ADAMTS6 PRSS12 OGFOD1 MMP2 F2 F9

2.12e-05238626M3468
CoexpressionNABA_ECM_REGULATORS

ADAMTS6 PRSS12 OGFOD1 MMP2 F2 F9

2.32e-05242626MM17062
CoexpressionMEBARKI_HCC_PROGENITOR_WNT_UP_CTNNB1_INDEPENDENT

SPOCK1 MRC2 MMP2

2.46e-0524623M38986
CoexpressionFOROUTAN_PRODRANK_TGFB_EMT_UP

ADAMTS6 SPOCK1 MRC2 JAG1 MMP2

7.75e-05185625M42503
CoexpressionNABA_MATRISOME_PRIMARY_METASTATIC_LUNG_TUMOR

LAMA1 LTBP2 F2

7.81e-0535623MM17054
CoexpressionGSE36891_UNSTIM_VS_POLYIC_TLR3_STIM_PERITONEAL_MACROPHAGE_DN

CPSF4L MCMBP ZNF217 SLC30A1 LARGE1

1.12e-04200625M8781
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HRGL2C

RELN ADAMTS6 PTPRZ1 MRC2 LAMA1 NOTCH1

1.19e-04325626M39053
CoexpressionBRUNEAU_HEART_GREAT_VESSELS_AND_VALVULOGENESIS

JAG1 NOTCH1

1.53e-048622M9884
CoexpressionHE_LIM_SUN_FETAL_LUNG_C3_OMD_POS_ENDOTHELIAL_CELL

SPOCK1 MRC2 JAG1 LGR4 ZNF217 LTBP2

1.92e-04355626M45758
CoexpressionMURARO_PANCREAS_MESENCHYMAL_STROMAL_CELL

COL6A3 SPOCK1 MRC2 JAG1 LTBP2 MMP2 SYDE1 NOTCH1

1.96e-04681628M39175
CoexpressionMEISSNER_BRAIN_HCP_WITH_H3K4ME3_AND_H3K27ME3

SLC6A11 STAC2 RELN PRSS12 JAG1 LAMA1 GLIS3 ZNF217 KLHL14 NOTCH1

1.98e-0410746210M1941
CoexpressionHEVNER_TELENCEPHALON_MENINGEAL_CELLS

COL6A3 LAMA1 MMP2

2.28e-0450623MM403
ToppCellLA-01._Fibroblast_I|LA / Chamber and Cluster_Paper

COL6A3 ITGBL1 SPOCK1 MRC2 GLIS3 LGR4 MMP2

7.20e-09179647dcb6ec9ae72b13fe388b72dace2815293fafe8ee
ToppCellLA-01._Fibroblast_I|World / Chamber and Cluster_Paper

COL6A3 ITGBL1 SPOCK1 MRC2 GLIS3 LGR4 LTBP2

9.74e-091876474ea486991f66c29728d127171a07b81404ec0b78
ToppCellLA-02._Fibroblast_II|World / Chamber and Cluster_Paper

COL6A3 ITGBL1 SPOCK1 MRC2 GLIS3 LGR4 LTBP2

1.30e-08195647a78b605b49acd8c9d68716266ca269dafcd910b9
ToppCellSubstantia_nigra-Endothelial-ENDOTHELIAL_TIP|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

COL6A3 MRC2 LAMA1 LTBP2 MMP2 KLHDC7A

1.12e-07159646cb2470b288c13e454a2a80115b0d5613b3f718e6
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

COL6A3 ITGBL1 ZNF732 PTPRZ1 MRC2 LTBP2

2.04e-071766469bc87cd5cda2372e1bce94c9dfd408eb1dfd8d0c
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

COL6A3 ITGBL1 ZNF732 PTPRZ1 MRC2 LTBP2

2.04e-071766463f8274a7ab67f9f8a8923193763a5543cfe4defa
ToppCell390C-Fibroblasts-Fibroblast-G|390C / Donor, Lineage, Cell class and subclass (all cells)

COL6A3 ITGBL1 MRC2 LTBP2 MMP2 SYDE1

2.33e-07180646137fc14859c89e1ecd98bee388bb58c04b835847
ToppCell390C-Fibroblasts-Fibroblast-G-|390C / Donor, Lineage, Cell class and subclass (all cells)

COL6A3 ITGBL1 MRC2 LTBP2 MMP2 SYDE1

2.33e-07180646cd6790de050151fedfa2c5ea6ad58b72665414b2
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL6A3 ITGBL1 SPOCK1 MRC2 LTBP2 MMP2

2.74e-0718564687c416d14ca6255bee39b16e7571553e36ee3069
ToppCellCOVID-19-Heart-Fib_2|COVID-19 / Disease (COVID-19 only), tissue and cell type

COL6A3 SPOCK1 MRC2 GLIS3 LGR4 LTBP2

2.74e-071856468f95d8e591bf7379d13f5a0545b0cb49e2b1ab5d
ToppCellTCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Ductal_Carcinoma-6|TCGA-Breast / Sample_Type by Project: Shred V9

ITGBL1 ADAMTS6 SPOCK1 GLIS3 LTBP2 MMP2

2.92e-07187646a96495803ba13fcfadd1d83b3cf5774f3fed0a20
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL6A3 ITGBL1 SPOCK1 MRC2 LTBP2 MMP2

3.31e-071916460fae1c2ef9f83ac7721d0a9d69455bf97eed9257
ToppCellLV-01._Fibroblast_I|LV / Chamber and Cluster_Paper

COL6A3 SPOCK1 MRC2 GLIS3 LGR4 LTBP2

3.51e-07193646dc17f3b9758936d428cf17f77a1ce6d4c479b165
ToppCellLV-02._Fibroblast_II|LV / Chamber and Cluster_Paper

COL6A3 SPOCK1 MRC2 GLIS3 LGR4 LTBP2

3.62e-07194646014d2feb5db2a6a35ef759761a41e466e108c3c1
ToppCellCOVID-19-Heart-Fib_2|Heart / Disease (COVID-19 only), tissue and cell type

COL6A3 SPOCK1 MRC2 GLIS3 LGR4 LTBP2

3.62e-07194646d91c9f2ec47319051fc398320693fddbe8bbd4d6
ToppCellLA-02._Fibroblast_II|LA / Chamber and Cluster_Paper

COL6A3 SPOCK1 MRC2 GLIS3 LGR4 LTBP2

3.62e-07194646234d1494c114cce77c619708bbcd8d5ce805f19b
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL6A3 ITGBL1 SPOCK1 MRC2 LTBP2 MMP2

3.73e-07195646f54bc4454270ff06e85596f98199372b50d0179f
ToppCellCOVID-19-Heart-Fib_1|Heart / Disease (COVID-19 only), tissue and cell type

COL6A3 SPOCK1 MRC2 GLIS3 LGR4 LTBP2

3.73e-07195646f423baa36ac7cdc383c033e35a7d17e6bf913323
ToppCell(1)_Osterolineage_cells-(11)_OLC-2|World / Cell class and subclass of bone marrow stroma cells in homeostatis

ITGBL1 SPOCK1 PTPRZ1 PRSS12 LTBP2 MMP2

3.73e-0719564678978d85273e5463a7f43e4c121e647fa6aba42b
ToppCellCOVID-19-Fibroblasts-Intermediate_pathological_FB|COVID-19 / group, cell type (main and fine annotations)

COL6A3 ITGBL1 MRC2 GLIS3 LTBP2 MMP2

3.96e-07197646f1c8936986123a3151140c374fcd62d6705c530b
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL6A3 ITGBL1 SPOCK1 MRC2 LTBP2 MMP2

3.96e-0719764671786e9432e2d649f5d86f639abb25e7102deb67
ToppCellCOVID-19-Fibroblasts|COVID-19 / group, cell type (main and fine annotations)

COL6A3 ITGBL1 MRC2 GLIS3 LTBP2 MMP2

3.96e-07197646fb847f2277609c31fffcdf49517243ce0684facf
ToppCelltumor_Lung-Fibroblasts-Myofibroblasts|tumor_Lung / Location, Cell class and cell subclass

COL6A3 ITGBL1 SPOCK1 MRC2 LTBP2 MMP2

4.08e-0719864631f9181dab689aabe9c6182c2ef7de65ba3f0ff6
ToppCellCOVID-19-lung-Fibroblast|lung / Disease (COVID-19 only), tissue and cell type

COL6A3 ITGBL1 MRC2 GLIS3 LTBP2 MMP2

4.08e-07198646df3de77216f5c5d6141ec44d01c56b942f611838
ToppCellmetastatic_Brain-Fibroblasts-FB-like_cells|metastatic_Brain / Location, Cell class and cell subclass

COL6A3 ITGBL1 SPOCK1 MRC2 LTBP2 MMP2

4.20e-0719964612133087eae9f0e9b6c13a71e8187117768e64ce
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL6A3 ITGBL1 SPOCK1 MRC2 LTBP2 MMP2

4.20e-071996469672230aa0bc6a7289050c955f5154ca183a5159
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL6A3 ITGBL1 SPOCK1 MRC2 LTBP2 MMP2

4.20e-07199646e18abe678da293bd01fae55e2f9ab6fdd643d02d
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL6A3 ITGBL1 SPOCK1 MRC2 LTBP2 MMP2

4.20e-071996461fd7bbb8727607e6507848602a19bc86882ef2d5
ToppCell(02)_MMP9/10+|World / shred by cell type by condition

SPOCK1 MRC2 JAG1 LTBP2 MMP2 ZXDB

4.20e-071996463f78eddeaa67d3b767aa38de765632166b09a4f0
ToppCellmedial-mesenchymal-Alveolar_Fibroblast|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

COL6A3 ITGBL1 PTPRZ1 MRC2 LTBP2 MMP2

4.33e-07200646c22cbfecee00183dd4be678f116ab9fd9ad0a4dd
ToppCellBronchus_Control_(B.)-Stromal-TX-Fibroblasts-2,_SCARA5|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

COL6A3 ITGBL1 SPOCK1 MRC2 LTBP2 MMP2

4.33e-072006462022df85df94ab8cbb4e80e3fe9894c01051c5e0
ToppCell3'-Parenchyma_lung-Mesenchymal|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL6A3 ITGBL1 SPOCK1 MRC2 LTBP2 MMP2

4.33e-07200646ba5ed66b05caa1be0bbf8d54c4e72a782b8d9833
ToppCellBronchus_Control_(B.)-Stromal-TX|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

COL6A3 ITGBL1 SPOCK1 MRC2 LTBP2 MMP2

4.33e-0720064669b41f5fb370aa8840a9ad7919d03ef1e57d1b5b
ToppCellmedial-2-mesenchymal-Alveolar_Fibroblast|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

COL6A3 ITGBL1 PTPRZ1 MRC2 LTBP2 MMP2

4.33e-07200646cc6062dac07916c29091fc6bee2b864d29e6525b
ToppCelltumor_Lymph_Node_/_Brain-Fibroblasts|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

COL6A3 ITGBL1 SPOCK1 MRC2 LTBP2 MMP2

4.33e-072006464f7e26b27bd51c32420ed8c2f52d070aee542159
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL6A3 ITGBL1 SPOCK1 MRC2 LTBP2 MMP2

4.33e-072006462e4ab7fbd94d3d865ef6188d3b4916d2bf1b8d89
ToppCelltumor_Lymph_Node_/_Brain-Fibroblasts-Myofibroblasts|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

COL6A3 ITGBL1 SPOCK1 MRC2 LTBP2 MMP2

4.33e-07200646ca777a7d001848f6d01c613ff2bda7e4f3e20521
ToppCellTracheal-NucSeq-Stromal-Fibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

COL6A3 ITGBL1 SPOCK1 MRC2 LTBP2 MMP2

4.33e-07200646b4ccffdd79526c85e5273d27b668dbddcddba1ee
ToppCellmedial-mesenchymal-Alveolar_Fibroblast-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

COL6A3 ITGBL1 PTPRZ1 MRC2 LTBP2 MMP2

4.33e-072006465c0716bf375c8158f7dc2c82bf5eaf37af594dd0
ToppCellParenchymal-10x5prime-Stromal-Fibroblastic-Fibro_adventitial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

COL6A3 ITGBL1 SPOCK1 MRC2 LTBP2 MMP2

4.33e-072006466b48ddde83bc6c941d557844aa214d4d2c8e736d
ToppCellParenchymal-10x5prime-Stromal-Fibroblastic-Fibro_myofibroblast|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

COL6A3 ITGBL1 SPOCK1 MRC2 LTBP2 MMP2

4.33e-0720064654806080b5e97859ee6a4a9b4f19e22021c218f5
ToppCellHippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Mgp_(Mgp)-|Hippocampus / BrainAtlas - Mouse McCarroll V32

COL6A3 MRC2 LAMA1 TAS1R1 LTBP2

4.72e-0710764513af691c8533418d2800a8eca61155896b559948
ToppCellHippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Mgp_(Mgp)|Hippocampus / BrainAtlas - Mouse McCarroll V32

COL6A3 MRC2 LAMA1 TAS1R1 LTBP2

4.72e-07107645a5a34bb9706527799ddb494d4f1bfc634c29e8a9
ToppCellCerebellum-Endothelial-ENDOTHELIAL_TIP|Cerebellum / BrainAtlas - Mouse McCarroll V32

COL6A3 MRC2 LAMA1 MMP2 KLHDC7A

2.43e-061496453980fa4f1986a2f164a1826ea043fb71f1d756cd
ToppCellFrontal_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_1|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

COL6A3 ITGBL1 MRC2 LAMA1 MMP2

2.85e-0615464565dbb60f636562eeba3dafadae9c0c7db2b27476
ToppCellChildren_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

STAC2 ITGBL1 ADAMTS6 LGR4 LTBP2

3.88e-06164645e3983f655cdba308fb192182829f17bef99ce0ba
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC6A11 COL6A3 MRC2 ZNF735 MMP2

3.88e-0616464501a7c335897128d3478b8b9b44fb461cab493084
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL6A3 ITGBL1 SPOCK1 MRC2 MMP2

4.89e-06172645e37c0b5b547a7345179ab258dd2141fec7064c17
ToppCell356C-Fibroblasts-Fibroblast-B_(Myofibroblast)|356C / Donor, Lineage, Cell class and subclass (all cells)

COL6A3 LGR4 LTBP2 MMP2 SYDE1

5.03e-0617364575e26a65071b0d2f30ed0b2aa9859c488f5cf362
ToppCell356C-Fibroblasts-Fibroblast-B_(Myofibroblast)-|356C / Donor, Lineage, Cell class and subclass (all cells)

COL6A3 LGR4 LTBP2 MMP2 SYDE1

5.03e-0617364526e2e674f5d312fa8f61c11b553dc6101f063b16
ToppCell390C-Fibroblasts-Fibroblast-B_(Myofibroblast)|390C / Donor, Lineage, Cell class and subclass (all cells)

COL6A3 ITGBL1 LTBP2 MMP2 SYDE1

5.47e-06176645852d3da0907fe87c0ef23d75a63ce07619cf0c54
ToppCell390C-Fibroblasts-Fibroblast-B_(Myofibroblast)-|390C / Donor, Lineage, Cell class and subclass (all cells)

COL6A3 ITGBL1 LTBP2 MMP2 SYDE1

5.47e-06176645d2df1e435996c51213e88270af9f928e9e09a6f5
ToppCellfacs-Lung-EPCAM-3m-Mesenchymal-adventitial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL6A3 ITGBL1 MMEL1 LTBP2 MMP2

5.78e-0617864527497dbfcf9bb4dd0bf7caa0bd78c7e85f5c18ee
ToppCellfacs-Lung-EPCAM-3m-Mesenchymal-Adventitial_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL6A3 ITGBL1 MMEL1 LTBP2 MMP2

5.78e-06178645d348a9550db940d204706529759dc51e30506b5f
ToppCellPosterior_cortex-Endothelial-ENDOTHELIAL_TIP|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

COL6A3 ITGBL1 MRC2 LAMA1 SEMA3B

5.78e-06178645cda7695411655bd6d0ba69e5041ca7530a9dad3a
ToppCellRA-01._Fibroblast_I|World / Chamber and Cluster_Paper

COL6A3 SPOCK1 MRC2 GLIS3 LGR4

6.27e-061816452b6ddeb53a79a658e2ba78527ff48c155b20daa6
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ITGBL1 ADAMTS6 MRC2 LTBP2 MMP2

6.27e-06181645d7e04e0ca549eac6d9b1192b6578f9b54943d54f
ToppCellmetastatic_Brain-Fibroblasts-Myofibroblasts|metastatic_Brain / Location, Cell class and cell subclass

COL6A3 ITGBL1 SPOCK1 MRC2 LTBP2

6.27e-06181645bd0b5f74f9c81ec0f1592710774a4fdf33d9d5a9
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL6A3 SPOCK1 MRC2 LTBP2 MMP2

6.44e-06182645d179b5deb07c20d49eb6c58d5a65904f8921de3a
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL6A3 SPOCK1 MRC2 LTBP2 MMP2

6.62e-0618364506a68fa2be36448064f4668be24a5b85ad85c6e8
ToppCelldroplet-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l1|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ITGBL1 SPOCK1 JAG1 LTBP2 MMP2

7.16e-061866454e983de6d2515082f9e555f4f949cec84281c140
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL6A3 ITGBL1 MRC2 LTBP2 MMP2

7.16e-061866455473283fb95cee556b1f6934cf72169b676b5bcc
ToppCelldroplet-Liver-HEPATOCYTES-1m-Mesenchymal-hepatic_stellate_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL6A3 RELN LAMA1 MMP2 SYDE1

7.35e-06187645b6ecf55014f246461bf1ca12f24cb4d046661fa4
ToppCelldroplet-Liver-HEPATOCYTES-1m-Mesenchymal-hepatic_stellate_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL6A3 RELN LAMA1 MMP2 SYDE1

7.35e-061876459fb15f24b9b364b0c4704ec98aec236eaec5411c
ToppCelldroplet-Liver-HEPATOCYTES-1m-Mesenchymal|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL6A3 RELN LAMA1 MMP2 SYDE1

7.35e-06187645e6afbaed352310a1cb49571a2aae18be1f533c9a
ToppCell-Donor_07|World / lung cells shred on cell class, cell subclass, sample id

COL6A3 ITGBL1 SPOCK1 LTBP2 MMP2

7.54e-06188645038f48e8daaeb72716e975d22a6b004a90654960
ToppCellCOVID-19-Heart-Fib_1|COVID-19 / Disease (COVID-19 only), tissue and cell type

COL6A3 SPOCK1 MRC2 GLIS3 LTBP2

7.54e-06188645fe361215f4ba841aa5e1e581fb56f2f4d3ccd201
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL6A3 ITGBL1 SPOCK1 LTBP2 MMP2

7.54e-06188645e18065bbc26d6f3774fd1f478fb41d8fb555fa26
ToppCell(2)_Fibroblasts-(22)_Fibro-3|World / Cell class and subclass of bone marrow stroma cells in homeostatis

ITGBL1 RELN PRSS12 SEMA3B MMP2

7.94e-061906453aed03b87ba2c8d479048c3ceef3ff5e38746c28
ToppCelldroplet-Kidney-nan-3m-Mesenchymal|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL6A3 ITGBL1 PTPRZ1 MRC2 MMP2

7.94e-061906452abeb013bb83c578e67dcb985ba44ca63134950b
ToppCellASK440-Mesenchymal|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq

COL6A3 ITGBL1 MRC2 LTBP2 MMP2

8.14e-06191645f12959eebb4167e1aa03de05d7711a702c58b3c9
ToppCellmetastatic_Lymph_Node-Fibroblasts-Myofibroblasts|metastatic_Lymph_Node / Location, Cell class and cell subclass

COL6A3 ITGBL1 SPOCK1 LTBP2 MMP2

8.14e-06191645aa43b472bc8362f79ae63f09f1ca764718bbf22c
ToppCellRV-01._Fibroblast_I|World / Chamber and Cluster_Paper

COL6A3 SPOCK1 MRC2 GLIS3 LGR4

8.14e-0619164570c067c54084bfb02c29bab085f4defd477194fb
ToppCellASK440-Mesenchymal-Fibroblast|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq

COL6A3 ITGBL1 MRC2 LTBP2 MMP2

8.14e-06191645387296b5377ef6839f0812e5b3529a10b5f7d530
ToppCelldroplet-Kidney-nan-3m-Mesenchymal-Stroma____fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL6A3 ITGBL1 PTPRZ1 MRC2 MMP2

8.14e-06191645d1205aab0937f2becfcd239610e9b78fb8a0c886
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL6A3 ITGBL1 MRC2 LTBP2 MMP2

8.35e-06192645f88aba74d6e8c594c32fe2bc095b5da28b4b28e9
ToppCellRV-01._Fibroblast_I|RV / Chamber and Cluster_Paper

COL6A3 SPOCK1 MRC2 GLIS3 LGR4

8.35e-06192645356160b113c3305a61ceeaff33ce3c9da0be2878
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-Degenerative_Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL6A3 ITGBL1 MRC2 LTBP2 MMP2

8.35e-0619264541a8326cd5bc19ad5041068501bab4c72399222e
ToppCellCOVID-19-Heart-Fib_+_EC_+_Pericyte|Heart / Disease (COVID-19 only), tissue and cell type

COL6A3 SPOCK1 MRC2 GLIS3 LTBP2

8.35e-0619264560b1312e84f6d6448365a952469c506c00b5fe93
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL6A3 ITGBL1 SPOCK1 LTBP2 MMP2

8.35e-06192645b9e4585bea280ca0ae159f0c6a2bf7b88a15a6e6
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL6A3 ITGBL1 SPOCK1 LTBP2 MMP2

8.35e-06192645c5f8e766453f87847b740d6988c524b3d0ef3765
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Astro-Astrocyte|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GAREM2 PTPRZ1 LAMA1 GLIS3 NOTCH1

8.56e-06193645b03d908d4b8940927f72c76a1b0f237d13f39056
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL6A3 ITGBL1 MRC2 LTBP2 MMP2

8.56e-06193645dc8e62df6121ee99b156aca6b1b3ae555739b6f2
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL6A3 ITGBL1 SPOCK1 MRC2 MMP2

8.56e-0619364509a9ab029f01234459a88e3e994fe90ef4cbb8c6
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Astro|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GAREM2 PTPRZ1 LAMA1 GLIS3 NOTCH1

8.56e-0619364540edc07b6e7f19f6ee885fa5af0b63ef1b0f2468
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.4.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL6A3 ITGBL1 SPOCK1 LTBP2 MMP2

8.56e-061936455bee7abc550ddaa28cbb3b9ecaf6b924ab175de0
ToppCelldroplet-Limb_Muscle-nan-3m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL6A3 ITGBL1 PRSS12 MRC2 MMP2

8.56e-06193645428b1a3ad87dff7f65de5161d40f102572a9341b
ToppCellLA|World / Chamber and Cluster_Paper

ITGBL1 SPOCK1 MRC2 GLIS3 LTBP2

8.56e-06193645d4bf89437216baf489ea0239136dcedf3b6714af
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Colon_Adenocarcinoma-10|TCGA-Colorectal / Sample_Type by Project: Shred V9

ITGBL1 SPOCK1 MRC2 SUSD5 LTBP2

8.56e-06193645194e7fa00a50cc4e026987b715323d125d79594e
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL6A3 ITGBL1 MRC2 LTBP2 MMP2

8.56e-06193645e2ee077fd381bd906e6b4329f22e7d106e422a7f
ToppCellRV-02._Fibroblast_II|RV / Chamber and Cluster_Paper

COL6A3 SPOCK1 MRC2 GLIS3 LGR4

8.78e-0619464511c79a8c56ece42713b04b321982e41e239f07a5
ToppCellTCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_NOS-3|TCGA-Stomach / Sample_Type by Project: Shred V9

ITGBL1 MRC2 SUSD5 LTBP2 MMP2

8.78e-061946452260cd817a6661e5eb6645b0c6786e18fd58371e
ToppCellMesenchymal_cells-Arteriolar_fibro.|World / Lineage and Cell class

COL6A3 ITGBL1 PRSS12 MRC2 MMP2

8.78e-06194645c1e8923a50b4138a1e4c054c0c17b7f7122aa8a9
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL6A3 ITGBL1 MRC2 LTBP2 MMP2

8.78e-0619464502b8102be9414d6964cd71019613edff6d88b893
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL6A3 ITGBL1 MRC2 LTBP2 MMP2

8.78e-0619464529f83cdd63314fff41258937d70b881a5503bfcc
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL6A3 ITGBL1 MRC2 LTBP2 MMP2

8.78e-06194645d3db241ea316bbcde6d16618193b474591ad5ce4
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL6A3 ITGBL1 MRC2 LTBP2 MMP2

9.00e-06195645df409f94f4e83be89f7a608058ee07ce3ce3a149
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL6A3 ITGBL1 MRC2 LTBP2 MMP2

9.00e-061956454243190ad291d56694e2155954dbaa879c9d3844
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL6A3 ITGBL1 SPOCK1 LTBP2 MMP2

9.00e-061956451236dc60288c7dd91868e86e9174a2dacd3b11b3
ToppCellRV-02._Fibroblast_II|World / Chamber and Cluster_Paper

COL6A3 SPOCK1 MRC2 GLIS3 LGR4

9.00e-06195645ce90b30dcdb56d4cd925cdb79fd9d7cefd998f48
DrugGLA-27

RELN GLA F9

1.92e-075623CID000163574
Drug2'-deoxythymidylyl-(3'-5')-2'-deoxyadenosine

JAG1 MMP2 NOTCH1

2.28e-0610623ctd:C028145
Diseasehemophilia B (is_implicated_in)

F2 F9

4.20e-062612DOID:12259 (is_implicated_in)
DiseaseHydrophthalmos

GLIS3 LTBP2

4.19e-055612C0020302
Diseaseretinal vein occlusion (is_implicated_in)

MMP2 F2

8.77e-057612DOID:1727 (is_implicated_in)
DiseaseBone Diseases

JAG1 MMP2

1.87e-0410612C0005940
DiseaseMarfan Syndrome

LTBP2 MMP2

2.28e-0411612C0024796
Diseasestenosing tenosynovitis

ADAMTS6 LTBP2

2.74e-0412612EFO_0010822
DiseaseMoyamoya Disease

GLA JAG1

5.60e-0417612C0026654
DiseaseGlioblastoma

JAG1 MMP2 NOTCH1

5.94e-0479613C0017636
Diseaseintraocular pressure measurement

COL6A3 RELN ADAMTS6 GLIS3 LTBP2 F2

6.36e-04509616EFO_0004695
DiseaseGiant Cell Glioblastoma

JAG1 MMP2 NOTCH1

7.11e-0484613C0334588
Diseasecongenital heart disease (is_implicated_in)

JAG1 NOTCH1

1.13e-0324612DOID:1682 (is_implicated_in)
DiseaseCarcinoma, Pancreatic Ductal

JAG1 NOTCH1

1.13e-0324612C0887833
DiseaseFibrosis, Liver

GLIS3 MMP2 F2

1.36e-03105613C0239946
DiseaseGlioblastoma Multiforme

JAG1 MMP2 NOTCH1

1.59e-03111613C1621958

Protein segments in the cluster

PeptideGeneStartEntry
SQDCPWYDQGFCKDG

CPSF4L

121

A6NMK7
WYDQGFCKDGPLCKY

CPSF4L

126

A6NMK7
RLDEFTCADCGLGYW

GRM2

531

Q14416
CWFCPGGEDEDRFDN

GVINP1

1101

Q7Z2Y8
KDCCWYEAALRDGNP

ABHD12B

126

Q7Z5M8
DWGVDLLKFDGCYCD

GLA

161

P06280
NIEKGWCYQGDCVPF

ADAMTS6

536

Q9UKP5
YDDDRKWGFCPDQGY

MMP2

381

P08253
VYSFCPDTCVWKGEG

KBTBD3

521

Q8NAB2
DLILYCGCEGWEPEY

OGFOD1

461

Q8N543
YGDARGKVDWGYCDC

PRSS12

151

P56730
DCPEYDRRFVGFGWN

LARGE1

666

O95461
RDSLNGYKCDCDPGW

NOTCH1

731

P46531
YWCNDGKTPGAVNAC

LYZ

81

P61626
FCNRTFDEYACWPDG

GLP1R

61

P43220
GGEAPSLEDWLCCEY

PEAK3

441

Q6ZS72
ECWCPFGFEGKNCEL

F9

116

P00740
FPCKDCGIWYRSERN

ZFPM1

241

Q8IX07
TQDYGKDERWGFCPI

MRC2

216

Q9UBG0
VASCQRPEGYWSDCG

LGR4

886

Q9BXB1
KCDQYWPADGSEEYG

PTPRZ1

1836

P23471
PCDDFYQFACGGWLR

MMEL1

111

Q495T6
CVCDEQWGGLYCDDP

RELN

2496

P78509
EKPYVCRECGRGFSW

PRDM9

661

Q9NQV7
PYVCRECGRGFSWQS

PRDM9

691

Q9NQV7
EKPYACTWEGCGWRF

KLF1

306

Q13351
CYCPEKGTWTELEGD

KLHL14

591

Q9P2G3
DCCNDERYWPAGQEP

DHX57

141

Q6P158
GEDFTCFWAGCPRRY

GLIS3

376

Q8NEA6
DPNTKSCARFWYGGC

COL6A3

3131

P12111
DECEDYGDPVCGTWK

LTBP2

1261

Q14767
LSCIDCGKDFWGDDY

LYAR

31

Q9NX58
GGLCCYDDEQDVWRP

KLHDC7A

506

Q5VTJ3
CRDYWVDTNGGCPYA

ERVFC1

96

P60507
KCDQGWYGDACQYPT

ITGBL1

116

O95965
CYGQLGCFSDEKPWA

PNLIPRP2

21

P54317
GPACLVKVYEDWDCF

MCMBP

236

Q9BTE3
YDEGDAFKCMCPGGW

JAG1

721

P78504
CFWAEKEPCMYPAGG

GPRASP1

676

Q5JY77
YCYPCTWGDCKVGES

GAREM2

551

Q75VX8
YAGDWSVCGRDFLPC

SYDE1

651

Q6ZW31
SCGEWYGLVQACGKD

SUSD5

186

O60279
QGVKCEECEDGHWGY

LAMA1

1021

P25391
ERPFLCDFDGCGWNF

ZXDB

451

P98169
ENPYTCEECGKAFNW

ZNF718

196

Q3SXZ3
YRCEECGKAFRWPSN

ZNF735

241

P0CB33
GEKPYECNECWRSFG

ZNF436

386

Q9C0F3
SDLYRCQPCGKEEWA

TAS1R1

531

Q7RTX1
DPYCAWDGVACTRFQ

SEMA3B

531

Q13214
WRCCQPFSGNKEQGY

STAC2

356

Q6ZMT1
HTGERPWECNECGKF

ZIK1

261

Q3SY52
LSNNEWCYCFQKPGG

SPOCK1

296

Q08629
CWRKVCPLFEGIGYA

SLC6A11

121

P48066
PYTCEQCGRGFDWKS

ZNF446

331

Q9NWS9
PYKCNECGKAFNWGS

ZNF841

396

Q6ZN19
YECEECGKAFLWGSQ

ZNF790

506

Q6PG37
KPYACGECGEAFAWL

ZSCAN18

411

Q8TBC5
YGCNMCGRRFKEPWF

ZNF217

156

O75362
FCRNPDGDEEGVWCY

F2

261

P00734
PYECEECGKAFGWST

ZNF732

501

B4DXR9
FSWKGCSEGDFCVNP

SLC30A1

271

Q9Y6M5
CGDTEAWKEGPYCQK

UBR2

151

Q8IWV8
DSGVYCCRIEVPGWF

TIMD4

106

Q96H15
PWYRFCRGCKIDCGE

USP32

1171

Q8NFA0
DYQREGSNWLKPCCG

TMEM266

71

Q2M3C6
YRCEECGKAFRWPSN

ZNF722

241

A0A1W2PQL4
PYQCAACGKAFGWRS

ZNF358

206

Q9NW07