Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	metalloendopeptidase activity	ADAMTS1 ADAM23 ADAM8 ADAM22 ADAMTS12 ECEL1	2.33e-05	120	95	6	GO:0004222
GeneOntologyMolecularFunction	ephrin receptor activity	EPHB4 EPHA6 EPHA3	9.57e-05	19	95	3	GO:0005003
GeneOntologyMolecularFunction	beta-adrenergic receptor kinase activity	GRK2 GRK3	1.34e-04	4	95	2	GO:0047696
GeneOntologyMolecularFunction	endopeptidase activity	PRSS54 ADAMTS1 ADAM23 ADAM8 ADAM22 ADAMTS12 FURIN ECEL1 PCSK4	2.10e-04	430	95	9	GO:0004175
GeneOntologyMolecularFunction	scavenger receptor activity	CD163 LRP1 DMBT1	2.81e-04	27	95	3	GO:0005044
GeneOntologyMolecularFunction	metallopeptidase activity	ADAMTS1 ADAM23 ADAM8 ADAM22 ADAMTS12 ECEL1	3.88e-04	200	95	6	GO:0008237
GeneOntologyMolecularFunction	L-leucine binding	UBR2 SESN1	4.63e-04	7	95	2	GO:0070728
GeneOntologyMolecularFunction	G protein-coupled receptor kinase activity	GRK2 GRK3	4.63e-04	7	95	2	GO:0004703
GeneOntologyMolecularFunction	lipoteichoic acid binding	CD6 DMBT1	4.63e-04	7	95	2	GO:0070891
GeneOntologyMolecularFunction	protein tyrosine kinase activity	EPHB4 EPHA6 ZAP70 PTK2 EPHA3	6.46e-04	145	95	5	GO:0004713
GeneOntologyMolecularFunction	heparan sulfate binding	FURIN DMBT1	7.89e-04	9	95	2	GO:1904399
GeneOntologyMolecularFunction	scaffold protein binding	SHANK1 CD163 GRK2 KCNA5	1.02e-03	93	95	4	GO:0097110
GeneOntologyMolecularFunction	peptidase activity	PRSS54 ADAMTS1 ADAM23 ADAM8 ADAM22 ADAMTS12 DPP9 FURIN ECEL1 PCSK4	1.10e-03	654	95	10	GO:0008233
GeneOntologyBiologicalProcess	positive regulation of catabolic process	RCHY1 SMURF1 FBXO11 ADAM8 SESN1 PTK2 SETD2 FBXO22 FURIN LRP1 SLC4A4 NANOS1 EIF2AK3	2.18e-05	701	96	13	GO:0009896
GeneOntologyBiologicalProcess	T cell aggregation	ADAM8 ZAP70	6.41e-05	3	96	2	GO:0070489
GeneOntologyBiologicalProcess	extracellular matrix organization	ADAMTS1 LAMC1 ADAM8 PTK2 ADAMTS12 FURIN LRP1 ANTXR1 EGFLAM	6.62e-05	377	96	9	GO:0030198
GeneOntologyBiologicalProcess	extracellular structure organization	ADAMTS1 LAMC1 ADAM8 PTK2 ADAMTS12 FURIN LRP1 ANTXR1 EGFLAM	6.75e-05	378	96	9	GO:0043062
GeneOntologyBiologicalProcess	external encapsulating structure organization	ADAMTS1 LAMC1 ADAM8 PTK2 ADAMTS12 FURIN LRP1 ANTXR1 EGFLAM	6.89e-05	379	96	9	GO:0045229
GeneOntologyBiologicalProcess	positive regulation of protein catabolic process	RCHY1 FBXO11 ADAM8 FBXO22 FURIN LRP1 EIF2AK3	9.52e-05	228	96	7	GO:0045732
GeneOntologyBiologicalProcess	cell projection morphogenesis	SHANK1 NES EPHA6 SMURF1 LAMC1 PTK2 CHRNB2 HOXA1 TAOK2 CELSR2 FBXO31 LRP1 EPHA3	1.16e-04	826	96	13	GO:0048858
GeneOntologyBiologicalProcess	ephrin receptor signaling pathway	EPHB4 EPHA6 PTK2 EPHA3	1.17e-04	54	96	4	GO:0048013
GeneOntologyBiologicalProcess	cell-substrate adhesion	LAMC1 ADAM8 PTK2 TAOK2 ADAMTS12 LRP1 ANTXR1 EGFLAM EPHA3	1.25e-04	410	96	9	GO:0031589
GeneOntologyBiologicalProcess	cerebrospinal fluid secretion	CELSR2 TP73	1.28e-04	4	96	2	GO:0033326
GeneOntologyBiologicalProcess	cell-substrate junction assembly	LAMC1 PTK2 TAOK2 LRP1 EPHA3	1.50e-04	108	96	5	GO:0007044
GeneOntologyBiologicalProcess	cell morphogenesis involved in neuron differentiation	SHANK1 EPHA6 SMURF1 LAMC1 PTK2 CHRNB2 HOXA1 TAOK2 CELSR2 FBXO31 LRP1 EPHA3	1.82e-04	748	96	12	GO:0048667
GeneOntologyBiologicalProcess	cell-substrate junction organization	LAMC1 PTK2 TAOK2 LRP1 EPHA3	2.01e-04	115	96	5	GO:0150115
Domain	EGF_2	EPHB4 ADAM23 LAMC1 ADAM8 ADAM22 CELSR2 NTN5 LRP1 EGFLAM EPHA3	1.19e-06	265	97	10	PS01186
Domain	Growth_fac_rcpt_	EPHB4 EPHA6 LAMC1 CELSR2 FURIN LRP1 PCSK4 EPHA3	1.52e-06	156	97	8	IPR009030
Domain	Pep_M12B_propep	ADAMTS1 ADAM23 ADAM8 ADAM22 ADAMTS12	1.70e-06	39	97	5	PF01562
Domain	Peptidase_M12B_N	ADAMTS1 ADAM23 ADAM8 ADAM22 ADAMTS12	1.70e-06	39	97	5	IPR002870
Domain	DISINTEGRIN_1	ADAMTS1 ADAM23 ADAM8 ADAM22 ADAMTS12	1.94e-06	40	97	5	PS00427
Domain	Reprolysin	ADAMTS1 ADAM23 ADAM8 ADAM22 ADAMTS12	1.94e-06	40	97	5	PF01421
Domain	ADAM_MEPRO	ADAMTS1 ADAM23 ADAM8 ADAM22 ADAMTS12	1.94e-06	40	97	5	PS50215
Domain	DISINTEGRIN_2	ADAMTS1 ADAM23 ADAM8 ADAM22 ADAMTS12	1.94e-06	40	97	5	PS50214
Domain	Peptidase_M12B	ADAMTS1 ADAM23 ADAM8 ADAM22 ADAMTS12	1.94e-06	40	97	5	IPR001590
Domain	-	EPHB4 EPHA6 LAMC1 FURIN PCSK4 EPHA3	2.16e-06	73	97	6	2.60.120.260
Domain	Disintegrin_dom	ADAMTS1 ADAM23 ADAM8 ADAM22 ADAMTS12	2.20e-06	41	97	5	IPR001762
Domain	SRCR	CD163 CD6 HHIPL1 DMBT1	3.82e-06	21	97	4	PF00530
Domain	-	ADAMTS1 ADAM23 ADAM8 ADAM22 ADAMTS12 ECEL1	3.98e-06	81	97	6	3.40.390.10
Domain	MetalloPept_cat_dom	ADAMTS1 ADAM23 ADAM8 ADAM22 ADAMTS12 ECEL1	3.98e-06	81	97	6	IPR024079
Domain	SAM	SHANK1 EPHB4 EPHA6 DGKH TP73 EPHA3	6.45e-06	88	97	6	SM00454
Domain	-	CD163 CD6 HHIPL1 DMBT1	7.95e-06	25	97	4	3.10.250.10
Domain	SR	CD163 CD6 HHIPL1 DMBT1	7.95e-06	25	97	4	SM00202
Domain	SRCR-like_dom	CD163 CD6 HHIPL1 DMBT1	9.36e-06	26	97	4	IPR017448
Domain	SRCR_1	CD163 CD6 HHIPL1 DMBT1	9.36e-06	26	97	4	PS00420
Domain	SRCR_2	CD163 CD6 HHIPL1 DMBT1	9.36e-06	26	97	4	PS50287
Domain	Galactose-bd-like	EPHB4 EPHA6 LAMC1 FURIN PCSK4 EPHA3	9.46e-06	94	97	6	IPR008979
Domain	SAM_DOMAIN	SHANK1 EPHB4 EPHA6 DGKH TP73 EPHA3	1.01e-05	95	97	6	PS50105
Domain	ADAM_Cys-rich	ADAMTS1 ADAM23 ADAM8 ADAM22	1.09e-05	27	97	4	IPR006586
Domain	ACR	ADAMTS1 ADAM23 ADAM8 ADAM22	1.09e-05	27	97	4	SM00608
Domain	SRCR	CD163 CD6 HHIPL1 DMBT1	1.09e-05	27	97	4	IPR001190
Domain	SAM	SHANK1 EPHB4 EPHA6 DGKH TP73 EPHA3	1.13e-05	97	97	6	IPR001660
Domain	-	SHANK1 EPHB4 EPHA6 DGKH TP73 EPHA3	1.88e-05	106	97	6	1.10.150.50
Domain	Quinoprot_gluc/sorb_DH	HHIPL2 LRP1 HHIPL1	2.89e-05	12	97	3	IPR011041
Domain	SAM/pointed	SHANK1 EPHB4 EPHA6 DGKH TP73 EPHA3	3.30e-05	117	97	6	IPR013761
Domain	RECEPTOR_TYR_KIN_V_2	EPHB4 EPHA6 EPHA3	4.74e-05	14	97	3	PS00791
Domain	RECEPTOR_TYR_KIN_V_1	EPHB4 EPHA6 EPHA3	4.74e-05	14	97	3	PS00790
Domain	Tyr_kinase_rcpt_V_CS	EPHB4 EPHA6 EPHA3	4.74e-05	14	97	3	IPR001426
Domain	EphA2_TM	EPHB4 EPHA6 EPHA3	4.74e-05	14	97	3	PF14575
Domain	Ephrin_rcpt_lig-bd_dom	EPHB4 EPHA6 EPHA3	4.74e-05	14	97	3	IPR001090
Domain	Eph_TM	EPHB4 EPHA6 EPHA3	4.74e-05	14	97	3	IPR027936
Domain	EPH_lbd	EPHB4 EPHA6 EPHA3	4.74e-05	14	97	3	SM00615
Domain	Ephrin_lbd	EPHB4 EPHA6 EPHA3	4.74e-05	14	97	3	PF01404
Domain	Tyr_kinase_ephrin_rcpt	EPHB4 EPHA6 EPHA3	4.74e-05	14	97	3	IPR016257
Domain	EPH_LBD	EPHB4 EPHA6 EPHA3	4.74e-05	14	97	3	PS51550
Domain	EGF_1	ADAM23 LAMC1 ADAM8 ADAM22 CELSR2 NTN5 LRP1 EGFLAM	5.49e-05	255	97	8	PS00022
Domain	EGF-like_CS	EPHB4 ADAM23 LAMC1 ADAM8 ADAM22 CELSR2 LRP1 EGFLAM	6.46e-05	261	97	8	IPR013032
Domain	Glc/Sorbosone_DH	HHIPL2 HHIPL1	7.98e-05	3	97	2	IPR012938
Domain	GSDH	HHIPL2 HHIPL1	7.98e-05	3	97	2	PF07995
Domain	Tyr_kinase_cat_dom	EPHB4 EPHA6 ZAP70 PTK2 EPHA3	9.49e-05	88	97	5	IPR020635
Domain	TyrKc	EPHB4 EPHA6 ZAP70 PTK2 EPHA3	9.49e-05	88	97	5	SM00219
Domain	ADAM_CR	ADAM23 ADAM8 ADAM22	1.05e-04	18	97	3	PF08516
Domain	-	ADAM23 ADAM8 ADAM22	1.45e-04	20	97	3	4.10.70.10
Domain	PROTEIN_KINASE_TYR	EPHB4 EPHA6 ZAP70 PTK2 EPHA3	1.50e-04	97	97	5	PS00109
Domain	Tyr_kinase_AS	EPHB4 EPHA6 ZAP70 PTK2 EPHA3	1.50e-04	97	97	5	IPR008266
Domain	Protein_kinase_ATP_BS	EPHB4 EPHA6 ZAP70 PTK2 TAOK2 GRK2 GRK3 EIF2AK3 EPHA3	1.57e-04	379	97	9	IPR017441
Domain	ZINC_PROTEASE	ADAMTS1 ADAM8 ADAM22 ADAMTS12 ECEL1	1.58e-04	98	97	5	PS00142
Domain	HMGI_Y	PATZ1 KMT2C	1.59e-04	4	97	2	PS00354
Domain	Disintegrin	ADAM23 ADAM8 ADAM22	1.69e-04	21	97	3	PF00200
Domain	DISIN	ADAM23 ADAM8 ADAM22	1.69e-04	21	97	3	SM00050
Domain	EGF	ADAM23 LAMC1 ADAM8 ADAM22 CELSR2 LRP1 EGFLAM	2.24e-04	235	97	7	SM00181
Domain	Ephrin_rec_like	EPHB4 EPHA6 EPHA3	2.87e-04	25	97	3	SM01411
Domain	Tyr-kin_ephrin_A/B_rcpt-like	EPHB4 EPHA6 EPHA3	2.87e-04	25	97	3	IPR011641
Domain	EGF-like_dom	ADAM23 LAMC1 ADAM8 ADAM22 CELSR2 LRP1 EGFLAM	3.19e-04	249	97	7	IPR000742
Domain	AT_hook	PATZ1 AHDC1 KMT2C	3.63e-04	27	97	3	SM00384
Domain	AT_hook_DNA-bd_motif	PATZ1 AHDC1 KMT2C	3.63e-04	27	97	3	IPR017956
Domain	Peptidase_S8_Asp-AS	FURIN PCSK4	3.95e-04	6	97	2	IPR023827
Domain	-	AASDH EIF2AK3	3.95e-04	6	97	2	2.140.10.10
Domain	Quinoprotein_ADH-like_fam	AASDH EIF2AK3	3.95e-04	6	97	2	IPR027295
Domain	EGF_LAM_2	LAMC1 CELSR2 NTN5	4.98e-04	30	97	3	PS50027
Domain	EGF_LAM_1	LAMC1 CELSR2 NTN5	4.98e-04	30	97	3	PS01248
Domain	P_proprotein	FURIN PCSK4	5.51e-04	7	97	2	PF01483
Domain	S8_pro-domain	FURIN PCSK4	5.51e-04	7	97	2	IPR032815
Domain	ZnF_UBR1	UBR2 FBXO11	5.51e-04	7	97	2	SM00396
Domain	PrprotnconvertsP	FURIN PCSK4	5.51e-04	7	97	2	IPR002884
Domain	GPCR_kinase	GRK2 GRK3	5.51e-04	7	97	2	IPR000239
Domain	ZF_UBR	UBR2 FBXO11	5.51e-04	7	97	2	PS51157
Domain	zf-UBR	UBR2 FBXO11	5.51e-04	7	97	2	PF02207
Domain	-	FURIN PCSK4	5.51e-04	7	97	2	3.30.70.850
Domain	Znf_UBR	UBR2 FBXO11	5.51e-04	7	97	2	IPR003126
Domain	S8_pro-domain	FURIN PCSK4	5.51e-04	7	97	2	PF16470
Domain	Pkinase_Tyr	EPHB4 EPHA6 ZAP70 PTK2 EPHA3	5.64e-04	129	97	5	PF07714
Domain	PROTEIN_KINASE_ATP	EPHB4 EPHA6 ZAP70 PTK2 TAOK2 GRK2 GRK3 EIF2AK3 EPHA3	6.39e-04	459	97	9	PS00107
Domain	Folate_rec	HHIPL2 HHIPL1	7.32e-04	8	97	2	PF03024
Domain	Folate_rcpt-like	HHIPL2 HHIPL1	7.32e-04	8	97	2	IPR018143
Domain	Ser-Thr/Tyr_kinase_cat_dom	EPHB4 EPHA6 ZAP70 PTK2 EPHA3	7.66e-04	138	97	5	IPR001245
Domain	EGF_Lam	LAMC1 CELSR2 NTN5	7.88e-04	35	97	3	SM00180
Domain	Laminin_EGF	LAMC1 CELSR2 NTN5	7.88e-04	35	97	3	PF00053
Domain	Peptidase_S8_His-AS	FURIN PCSK4	9.39e-04	9	97	2	IPR022398
Domain	Peptidase_S8_Ser-AS	FURIN PCSK4	9.39e-04	9	97	2	IPR023828
Domain	Prot_kinase_dom	EPHB4 EPHA6 ZAP70 PTK2 TAOK2 GRK2 GRK3 EIF2AK3 EPHA3	9.99e-04	489	97	9	IPR000719
Domain	Laminin_EGF	LAMC1 CELSR2 NTN5	1.00e-03	38	97	3	IPR002049
Domain	PROTEIN_KINASE_DOM	EPHB4 EPHA6 ZAP70 PTK2 TAOK2 GRK2 GRK3 EIF2AK3 EPHA3	1.06e-03	493	97	9	PS50011
Domain	-	HHIPL2 LRP1 HHIPL1	1.08e-03	39	97	3	2.120.10.30
Domain	Peptidase_S8_subtilisin-rel	FURIN PCSK4	1.17e-03	10	97	2	IPR015500
Domain	SUBTILASE_ASP	FURIN PCSK4	1.17e-03	10	97	2	PS00136
Domain	SUBTILASE_HIS	FURIN PCSK4	1.17e-03	10	97	2	PS00137
Domain	SUBTILASE_SER	FURIN PCSK4	1.17e-03	10	97	2	PS00138
Domain	EGF_3	ADAM23 ADAM8 ADAM22 CELSR2 LRP1 EGFLAM	1.42e-03	235	97	6	PS50026
Domain	-	FURIN PCSK4	1.42e-03	11	97	2	3.40.50.200
Domain	Ephrin_rec_like	EPHB4 EPHA3	1.42e-03	11	97	2	PF07699
Domain	Peptidase_S8/S53_dom	FURIN PCSK4	1.42e-03	11	97	2	IPR000209
Domain	Peptidase_S8	FURIN PCSK4	1.42e-03	11	97	2	PF00082
Domain	SAM_2	DGKH TP73 EPHA3	1.44e-03	43	97	3	PF07647
Domain	6-blade_b-propeller_TolB-like	HHIPL2 LRP1 HHIPL1	1.75e-03	46	97	3	IPR011042
Domain	Kinase-like_dom	EPHB4 EPHA6 ZAP70 PTK2 TAOK2 GRK2 GRK3 EIF2AK3 EPHA3	2.03e-03	542	97	9	IPR011009
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	UBR2 ABAT EPHA6 SMURF1 PEX14 ATP9B DGKH PTPN18 SESN1 AHDC1 PTK2 SBNO2 KMT2C CAMK2N1 GRK3 DPP9 LRP1 ANTXR1 SAMM50 PLOD1 PDZD2	8.63e-10	1489	98	21	28611215
Pubmed	Promotion of proliferation in the developing cerebral cortex by EphA4 forward signaling.	EPHB4 NES EPHA6 EPHA3	5.04e-07	23	98	4	19542359
Pubmed	Sleeping Beauty mutagenesis reveals cooperating mutations and pathways in pancreatic adenocarcinoma.	FBXO11 PTK2 KMT2C	2.57e-06	10	98	3	22421440
Pubmed	The protein tyrosine kinase family of the human genome.	EPHB4 EPHA6 ZAP70 PTK2 EPHA3	3.91e-06	83	98	5	11114734
Pubmed	Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.	EPHB4 SMURF1 DGKH PTK2 ADAMTS12 KCNA5 DPP9 FURIN LRP1 ECEL1 PCSK4	6.92e-06	730	98	11	34857952
Pubmed	Ephrin Ligands and Eph Receptors Show Regionally Restricted Expression in the Developing Palate and Tongue.	EPHB4 EPHA6 EPHA3	7.72e-06	14	98	3	26941654
Pubmed	Pirh2, a ubiquitin E3 ligase, inhibits p73 transcriptional activity by promoting its ubiquitination.	RCHY1 TP73	7.86e-06	2	98	2	21994467
Pubmed	Low-density lipoprotein receptor-related protein 1 is a novel modulator of radial glia stem cell proliferation, survival, and differentiation.	NES LRP1	7.86e-06	2	98	2	27258849
Pubmed	Altered airway and cardiac responses in mice lacking G protein-coupled receptor kinase 3.	GRK2 GRK3	7.86e-06	2	98	2	10198406
Pubmed	G-protein coupled receptor kinase 2 and 3 expression in human detrusor cultured smooth muscle cells.	GRK2 GRK3	7.86e-06	2	98	2	11762794
Pubmed	Temporal Properties of Cone ERGs of Pikachurin Null Mutant Mouse.	GRM6 EGFLAM	7.86e-06	2	98	2	26990161
Pubmed	The low-density-lipoprotein receptor-related protein (LRP) is processed by furin in vivo and in vitro.	FURIN LRP1	7.86e-06	2	98	2	8546712
Pubmed	The p73 tumor suppressor is targeted by Pirh2 RING finger E3 ubiquitin ligase for the proteasome-dependent degradation.	RCHY1 TP73	7.86e-06	2	98	2	21852228
Pubmed	Cloning of GRK2 cDNA from S49 murine lymphoma cells.	GRK2 GRK3	7.86e-06	2	98	2	8638670
Pubmed	Dissecting the roles of GRK2 and GRK3 in μ-opioid receptor internalization and β-arrestin2 recruitment using CRISPR/Cas9-edited HEK293 cells.	GRK2 GRK3	7.86e-06	2	98	2	33060647
Pubmed	G protein--coupled receptor kinases.	GRK2 GRK3	7.86e-06	2	98	2	8035170
Pubmed	Oocyte-specific deletion of furin leads to female infertility by causing early secondary follicle arrest in mice.	ADAMTS1 FURIN	7.86e-06	2	98	2	28569793
Pubmed	Nestin regulates prostate cancer cell invasion by influencing the localisation and functions of FAK and integrins.	NES PTK2	7.86e-06	2	98	2	24610946
Pubmed	Localization of Kex2-like processing endoproteases, furin and PC4, within mouse testis by in situ hybridization.	FURIN PCSK4	7.86e-06	2	98	2	8422932
Pubmed	G6PD-mediated increase in de novo NADP+ biosynthesis promotes antioxidant defense and tumor metastasis.	RCHY1 TP73	7.86e-06	2	98	2	35857842
Pubmed	Proteolytic processing of the 600 kd low density lipoprotein receptor-related protein (LRP) occurs in a trans-Golgi compartment.	FURIN LRP1	7.86e-06	2	98	2	2112085
Pubmed	Laminin α1 is essential for mouse cerebellar development.	NES LAMC1 PTK2	1.43e-05	17	98	3	21983115
Pubmed	Disruption of segmental neural crest migration and ephrin expression in delta-1 null mice.	EPHB4 EPHA6 EPHA3	1.43e-05	17	98	3	12217323
Pubmed	Ephrin-B2 and EphB1 mediate retinal axon divergence at the optic chiasm.	EPHB4 NES EPHA3	1.43e-05	17	98	3	12971893
Pubmed	Expression of Ephs and ephrins in developing mouse inner ear.	EPHB4 EPHA6 EPHA3	2.03e-05	19	98	3	12684176
Pubmed	Human NK cells express CC chemokine receptors 4 and 8 and respond to thymus and activation-regulated chemokine, macrophage-derived chemokine, and I-309.	GRK2 GRK3	2.35e-05	3	98	2	10754297
Pubmed	Metalloproteinase-like, disintegrin-like, cysteine-rich proteins MDC2 and MDC3: novel human cellular disintegrins highly expressed in the brain.	ADAM23 ADAM22	2.35e-05	3	98	2	9693107
Pubmed	Prognostic Value of Phosphotyrosine Phosphatases in Hepatocellular Carcinoma.	PTPN18 PTPRN	2.35e-05	3	98	2	29742497
Pubmed	Chemical corrector treatment ameliorates increased seizure susceptibility in a mouse model of familial epilepsy.	ADAM23 ADAM22	2.35e-05	3	98	2	25485908
Pubmed	Disruption of LGI1-linked synaptic complex causes abnormal synaptic transmission and epilepsy.	ADAM23 ADAM22	2.35e-05	3	98	2	20133599
Pubmed	Secretion-Positive LGI1 Mutations Linked to Lateral Temporal Epilepsy Impair Binding to ADAM22 and ADAM23 Receptors.	ADAM23 ADAM22	2.35e-05	3	98	2	27760137
Pubmed	Dipeptidyl peptidase 9 subcellular localization and a role in cell adhesion involving focal adhesion kinase and paxillin.	PTK2 DPP9	2.35e-05	3	98	2	25486458
Pubmed	p73 regulates maintenance of neural stem cell.	NES TP73	2.35e-05	3	98	2	20977890
Pubmed	Differential effects of CC chemokines on CC chemokine receptor 5 (CCR5) phosphorylation and identification of phosphorylation sites on the CCR5 carboxyl terminus.	GRK2 GRK3	2.35e-05	3	98	2	10085131
Pubmed	Cardiac function in mice overexpressing the beta-adrenergic receptor kinase or a beta ARK inhibitor.	GRK2 GRK3	2.35e-05	3	98	2	7761854
Pubmed	The N-termini of GRK2 and GRK3 simulate the stimulating effects of RKIP on β-adrenoceptors.	GRK2 GRK3	2.35e-05	3	98	2	31604529
Pubmed	Orphanin FQ/nociceptin-mediated desensitization of opioid receptor-like 1 receptor and mu opioid receptors involves protein kinase C: a molecular mechanism for heterologous cross-talk.	GRK2 GRK3	2.35e-05	3	98	2	12130708
Pubmed	ADAMTS-1 is an active metalloproteinase associated with the extracellular matrix.	ADAMTS1 FURIN	2.35e-05	3	98	2	10373500
Pubmed	Pirh2, an E3 ligase, regulates the AIP4-p73 regulatory pathway by modulating AIP4 expression and ubiquitination.	RCHY1 TP73	2.35e-05	3	98	2	33569599
Pubmed	Soluble Receptors Affecting Stroke Outcomes: Potential Biomarkers and Therapeutic Tools.	CD163 LRP1	2.35e-05	3	98	2	33498620
Pubmed	Functional phylogenetic analysis of LGI proteins identifies an interaction motif crucial for myelination.	ADAM23 ADAM22	2.35e-05	3	98	2	24715463
Pubmed	Unified nomenclature for Eph family receptors and their ligands, the ephrins. Eph Nomenclature Committee.	EPHB4 EPHA6 EPHA3	2.78e-05	21	98	3	9267020
Pubmed	Roles of Eph receptors and ephrins in segmental patterning.	EPHB4 EPHA6 EPHA3	2.78e-05	21	98	3	11128993
Pubmed	Eph receptors and ephrins demarcate cerebellar lobules before and during their formation.	EPHB4 EPHA6 EPHA3	2.78e-05	21	98	3	10495276
Pubmed	Developmental expression of Eph and ephrin family genes in mammalian small intestine.	EPHB4 EPHA6 EPHA3	2.78e-05	21	98	3	20112066
Pubmed	Eph receptors and ephrins: regulators of guidance and assembly.	EPHB4 EPHA6 EPHA3	2.78e-05	21	98	3	10730216
Pubmed	Composition and Regulation of the Cellular Repertoire of SCF Ubiquitin Ligases.	CAND2 FBXO11 FBXO22 FBXO31	2.92e-05	62	98	4	29103612
Pubmed	Zic deficiency in the cortical marginal zone and meninges results in cortical lamination defects resembling those in type II lissencephaly.	NES LAMC1 TP73	3.21e-05	22	98	3	18448648
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	EPHB4 UBR2 LAMC1 ADAM22 FBXO22 CELSR2 BTD FURIN LRP1 ANTXR1 ECEL1 PLOD1 EIF2AK3	3.29e-05	1201	98	13	35696571
Pubmed	Thalamic afferents influence cortical progenitors via ephrin A5-EphA4 interactions.	NES EPHA6 EPHA3	3.69e-05	23	98	3	25480914
Pubmed	Eph receptors and their ephrin ligands are expressed in developing mouse pancreas.	EPHB4 EPHA6 EPHA3	4.21e-05	24	98	3	16446123
Pubmed	Role of tyrosine phosphorylation in ligand-independent sequestration of CXCR4 in human primary monocytes-macrophages.	PTK2 GRK3	4.70e-05	4	98	2	11668182
Pubmed	Essential role of beta-adrenergic receptor kinase 1 in cardiac development and function.	GRK2 GRK3	4.70e-05	4	98	2	8917529
Pubmed	A LewisX glycoprotein screen identifies the low density lipoprotein receptor-related protein 1 (LRP1) as a modulator of oligodendrogenesis in mice.	NES LRP1	4.70e-05	4	98	2	23615909
Pubmed	Hierarchical organization of multi-site phosphorylation at the CXCR4 C terminus.	GRK2 GRK3	4.70e-05	4	98	2	23734232
Pubmed	ADAMTS 1, 4, 12, and 13 levels in maternal blood, cord blood, and placenta in preeclampsia.	ADAMTS1 ADAMTS12	4.70e-05	4	98	2	29135310
Pubmed	Proprotein and prohormone convertases: a family of subtilases generating diverse bioactive polypeptides.	FURIN PCSK4	4.70e-05	4	98	2	10701998
Pubmed	Reduced expression of G protein-coupled receptor kinases in schizophrenia but not in schizoaffective disorder.	GRK2 GRK3	4.70e-05	4	98	2	21784156
Pubmed	Phosphorylation of the type 1A angiotensin II receptor by G protein-coupled receptor kinases and protein kinase C.	GRK2 GRK3	4.70e-05	4	98	2	8662816
Pubmed	Identification of tyrosine kinases expressed in the male mouse gubernaculum during development.	EPHB4 PTK2 EPHA3	4.77e-05	25	98	3	15254900
Pubmed	Whole-genome sequencing reveals host factors underlying critical COVID-19.	ACSL6 DPP9 SLC22A31	4.77e-05	25	98	3	35255492
Pubmed	Time-resolved mass spectrometry of tyrosine phosphorylation sites in the epidermal growth factor receptor signaling network reveals dynamic modules.	EPHB4 UBAP2 PTPN18 PTK2	6.18e-05	75	98	4	15951569
Pubmed	CDC25A, VAV1, TP73, BRCA1 and ZAP70 gene overexpression correlates with radiation response in colorectal cancer.	ZAP70 TP73	7.82e-05	5	98	2	21344162
Pubmed	A critical function of the pial basement membrane in cortical histogenesis.	NES LAMC1	7.82e-05	5	98	2	12122064
Pubmed	The homeodomain transcription factor Hoxa2 interacts with and promotes the proteasomal degradation of the E3 ubiquitin protein ligase RCHY1.	RCHY1 HOXA1	7.82e-05	5	98	2	24244684
Pubmed	Metalloproteinase Adamts16 Is Required for Proper Closure of the Optic Fissure.	ADAM23 ADAMTS12	7.82e-05	5	98	2	29625437
Pubmed	Enhanced contractility and decreased beta-adrenergic receptor kinase-1 in mice lacking endogenous norepinephrine and epinephrine.	GRK2 GRK3	7.82e-05	5	98	2	10338466
Pubmed	The new enzymology of precursor processing endoproteases.	FURIN PCSK4	7.82e-05	5	98	2	1429684
Pubmed	Long-term potentiation modulates synaptic phosphorylation networks and reshapes the structure of the postsynaptic interactome.	SHANK1 IQSEC2 ADAM22 PTK2 TAOK2 LRP1	8.05e-05	251	98	6	27507650
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	SHANK1 NES UBAP2 PATZ1 IQSEC2 ADAM22 PTK2 TAOK2 CELSR2 LRP1 SLC4A4	8.66e-05	963	98	11	28671696
Pubmed	Maturation of human dendritic cells is accompanied by functional remodelling of the ubiquitin-proteasome system.	UBR2 FBXO11 FBXO22 FBXO31	1.01e-04	85	98	4	19028597
Pubmed	beta2-Adrenergic receptor regulation by GIT1, a G protein-coupled receptor kinase-associated ADP ribosylation factor GTPase-activating protein.	GRK2 GRK3	1.17e-04	6	98	2	9826657
Pubmed	Quantitative genetic analysis of brain copper and zinc in BXD recombinant inbred mice.	EPHA6 EPHA3	1.17e-04	6	98	2	16910173
Pubmed	Opposing gradients of ephrin-As and EphA7 in the superior colliculus are essential for topographic mapping in the mammalian visual system.	EPHA6 EPHA3	1.17e-04	6	98	2	15996548
Pubmed	The C terminus of p73 is essential for hippocampal development.	NES TP73	1.17e-04	6	98	2	32571922
Pubmed	Protein tyrosine kinase 2 beta (PTK2B), but not focal adhesion kinase (FAK), is expressed in a sexually dimorphic pattern in developing mouse gonads.	PTK2 DDX4	1.17e-04	6	98	2	20737507
Pubmed	Function of the cytoplasmic tail of human calcitonin receptor-like receptor in complex with receptor activity-modifying protein 2.	GRK2 GRK3	1.17e-04	6	98	2	20074556
Pubmed	Epilepsy-related ligand/receptor complex LGI1 and ADAM22 regulate synaptic transmission.	ADAM23 ADAM22	1.17e-04	6	98	2	16990550
Pubmed	Combinatorial depletions of G-protein coupled receptor kinases in immune cells identify pleiotropic and cell type-specific functions.	GRK2 GRK3	1.17e-04	6	98	2	36451830
Pubmed	The Gpr1/Zdbf2 locus provides new paradigms for transient and dynamic genomic imprinting in mammals.	ADAM23 DDX4	1.64e-04	7	98	2	24589776
Pubmed	Proteolytic processing in the secretory pathway.	FURIN PCSK4	1.64e-04	7	98	2	10409610
Pubmed	Abundance of ADAM-8, -9, -10, -12, -15 and -17 and ADAMTS-1 in mouse uterus during the oestrous cycle.	ADAMTS1 ADAM8	1.64e-04	7	98	2	15907280
Pubmed	The family of subtilisin/kexin like pro-protein and pro-hormone convertases: divergent or shared functions.	FURIN PCSK4	1.64e-04	7	98	2	7819324
Pubmed	Laminin-10/11 and fibronectin differentially prevent apoptosis induced by serum removal via phosphatidylinositol 3-kinase/Akt- and MEK1/ERK-dependent pathways.	LAMC1 PTK2	1.64e-04	7	98	2	11891225
Pubmed	Premature aggregation of type IV collagen and early lethality in lysyl hydroxylase 3 null mice.	LAMC1 PLOD1	1.64e-04	7	98	2	15377789
Pubmed	Members of the G protein-coupled receptor kinase family that phosphorylate the beta2-adrenergic receptor facilitate sequestration.	GRK2 GRK3	1.64e-04	7	98	2	8672451
Pubmed	LGI1 is a Nogo receptor 1 ligand that antagonizes myelin-based growth inhibition.	ADAM23 ADAM22	1.64e-04	7	98	2	20463223
Pubmed	Determination of bradykinin B2 receptor in vivo phosphorylation sites and their role in receptor function.	GRK2 GRK3	1.64e-04	7	98	2	11517230
Pubmed	Protein interactome reveals converging molecular pathways among autism disorders.	SHANK1 LAMC1 KCTD1 CD163 HOXA1 SETD2 VPS51 MTUS2	1.90e-04	560	98	8	21653829
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	SHANK1 ACSL6 NES RTCB RCHY1 IQSEC2 SMURF1 ADAM22 GRK2 SAMM50 SLC4A4 VPS51 MTUS2	1.91e-04	1431	98	13	37142655
Pubmed	The DNA sequence of human chromosome 22.	RTCB PATZ1 GRK3 ZNF74 CACNA1I SAMM50	2.12e-04	300	98	6	10591208
Pubmed	Mistargeting hippocampal axons by expression of a truncated Eph receptor.	EPHA6 EPHA3	2.18e-04	8	98	2	12124402
Pubmed	EphA receptors direct the differentiation of mammalian neural precursor cells through a mitogen-activated protein kinase-dependent pathway.	NES EPHA3	2.18e-04	8	98	2	15145949
Pubmed	The identification of seven metalloproteinase-disintegrin (ADAM) genes from genomic libraries.	ADAM23 ADAM22	2.18e-04	8	98	2	10524237
Pubmed	Regulation of bone morphogenetic protein activity by pro domains and proprotein convertases.	FURIN PCSK4	2.18e-04	8	98	2	9885250
Pubmed	Low Density Lipoprotein-Receptor Related Protein 1 Is Differentially Expressed by Neuronal and Glial Populations in the Developing and Mature Mouse Central Nervous System.	NES LRP1	2.18e-04	8	98	2	27280679
Pubmed	Chromosomal assignment of the genes for proprotein convertases PC4, PC5, and PACE 4 in mouse and human.	FURIN PCSK4	2.18e-04	8	98	2	7782070
Pubmed	Signals transduced by Ca(2+)/calcineurin and NFATc3/c4 pattern the developing vasculature.	EPHB4 EPHA6 EPHA3	2.30e-04	42	98	3	11439183
Pubmed	A family of mammalian F-box proteins.	FBXO11 FBXO22 FBXO31	2.30e-04	42	98	3	10531037
Pubmed	The activation and physiological functions of the proprotein convertases.	FURIN PCSK4	2.79e-04	9	98	2	18343183
Interaction	ADAM19 interactions	ADAM23 ADAM8 ADAM22 FURIN ECEL1	3.05e-06	48	95	5	int:ADAM19
Interaction	ADAM8 interactions	ADAM23 ADAM8 ADAM22	1.63e-05	11	95	3	int:ADAM8
GeneFamily	Fibronectin type III domain containing\|Sterile alpha motif domain containing\|EPH receptors	EPHB4 EPHA6 EPHA3	1.72e-05	14	67	3	1095
GeneFamily	Sterile alpha motif domain containing	SHANK1 EPHB4 EPHA6 DGKH EPHA3	1.85e-05	88	67	5	760
GeneFamily	ADAM metallopeptidase domain containing\|CD molecules	ADAM23 ADAM8 ADAM22	1.33e-04	27	67	3	47
GeneFamily	Ubiquitin protein ligase E3 component n-recognins	UBR2 FBXO11	2.81e-04	7	67	2	785
GeneFamily	Cyclins\|F-boxes other	FBXO11 FBXO22 FBXO31	4.04e-04	39	67	3	560
GeneFamily	Proprotein convertase subtilisin/kexin family	FURIN PCSK4	4.79e-04	9	67	2	973
GeneFamily	ADAM metallopeptidases with thrombospondin type 1 motif	ADAMTS1 ADAMTS12	2.22e-03	19	67	2	50
GeneFamily	Fibronectin type III domain containing	EPHB4 EPHA6 EGFLAM EPHA3	2.94e-03	160	67	4	555
GeneFamily	Acyl-CoA synthetase family	ACSL6 AASDH	4.15e-03	26	67	2	40
GeneFamily	Zinc fingers C2H2-type\|Lysine methyltransferases\|PR/SET domain family	KMT2C SETD2	7.03e-03	34	67	2	487
ToppCell	390C-Myeloid-Dendritic-cDC_proliferating_2\|Dendritic / Donor, Lineage, Cell class and subclass (all cells)	NES ZAP70 ADAM22 CAMK2N1 NUDT6 FBXO31	1.59e-06	162	98	6	a957c7e347189b72fbd47db3075bb5e879a21c67
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ADAM22 ADAMTS12 LRP1 ANTXR1 SLC4A4 EPHA3	2.83e-06	179	98	6	02c90d8306016365ed811f0c63cfb3ac7b85464c
ToppCell	COVID-19-Heart-EC_+_Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	NES ADAMTS1 ADAMTS12 EGFLAM EPHA3 PDZD2	3.12e-06	182	98	6	e67f3234165199085c793915ebb1f9bbd845e933
ToppCell	Pericytes-Donor_03\|World / lung cells shred on cell class, cell subclass, sample id	ADAMTS1 ADAMTS12 CAMK2N1 KCNA5 EGFLAM EPHA3	3.22e-06	183	98	6	d04deef7cd4e1738227a6593b84874ce0168c773
ToppCell	droplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l44-58\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SHANK1 ADAM23 PEX14 AASDH WNT16 DMBT1	3.22e-06	183	98	6	dc9602bed3136db91faeffef177006246dc92743
ToppCell	LPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ADAMTS1 GRK3 EGFLAM SLC4A4 EPHA3 PDZD2	3.32e-06	184	98	6	327ff3ac8d2fecdd5d242bdc34f0dfdb1c59a68b
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ADAMTS1 ADAM22 ADAMTS12 ANTXR1 SLC4A4 EPHA3	3.43e-06	185	98	6	6712512100ccef456d2e2bd201d0987986c92ac9
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ADAM22 ADAMTS12 LRP1 ANTXR1 SLC4A4 EPHA3	3.43e-06	185	98	6	3b2dfc8f4c87be516265dbecfc251276034d0efd
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	AOX1 ADAMTS12 CAMK2N1 GRK3 LRP1 ANTXR1	4.12e-06	191	98	6	b13229bb7f3713a392271aaf5dbae3edd1b9fe5a
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ADAMTS1 AOX1 ADAMTS12 CAMK2N1 LRP1 ANTXR1	4.24e-06	192	98	6	3d0cb19f037f604253d7d728689aeaa94251e92b
ToppCell	Control-Stromal-Myofibroblast\|World / Disease state, Lineage and Cell class	ADAMTS1 AOX1 LAMC1 ADAMTS12 CAMK2N1 ANTXR1	4.50e-06	194	98	6	3c2266772c5b56e8e02a461e5193e29588028ee9
ToppCell	LPS-antiTNF-Stromal_mesenchymal\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ADAMTS1 ADAMTS12 CAMK2N1 LRP1 ANTXR1 EPHA3	4.50e-06	194	98	6	6e13549f697f7478b34fe71f7dd9d63c5d3db22e
ToppCell	Control-Stromal-Myofibroblast\|Control / Disease state, Lineage and Cell class	ADAMTS1 AOX1 LAMC1 ADAMTS12 CAMK2N1 ANTXR1	4.64e-06	195	98	6	ffcf76cd72e43d8cf1058a49c76e0956065038bc
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ADAMTS1 AOX1 LAMC1 ADAMTS12 CAMK2N1 LRP1	4.64e-06	195	98	6	4243190ad291d56694e2155954dbaa879c9d3844
ToppCell	facs-Heart-RA-18m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHB4 NES ARHGEF15 TAOK2 KCNA5 GARRE1	4.64e-06	195	98	6	30c75761079fa1e1a3b84d23c88a222f459d5ce5
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW08-Neuronal-Intermediate\|GW08 / Sample Type, Dataset, Time_group, and Cell type.	ADAM22 FBXO22 ECEL1 PCSK4 EIF2AK3 PDZD2	5.36e-06	200	98	6	401d50fa394fa863fa7836344110ae5c7af3250a
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	EPHB4 DGKH ARHGEF15 TAOK2 KMT2C GARRE1	5.36e-06	200	98	6	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Gen_Cap\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	EPHB4 DGKH PTK2 ARHGEF15 TAOK2 GARRE1	5.36e-06	200	98	6	a2b9d1cd291d17abddc3ee2e242121412c864b8b
ToppCell	PND07-28-samps-Mesenchymal-Mesenchymal_stem_cell\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	SHANK1 CAND2 AHDC1 MZF1 NANOS1	1.32e-05	137	98	5	ed81624b9167255ce88dcf6ad7f1636376ea0525
ToppCell	PND07-28-samps-Mesenchymal-Mesenchymal_stem_cell-Mesenchymal_fibroblast\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	SHANK1 CAND2 AHDC1 MZF1 NANOS1	1.32e-05	137	98	5	47859aa25f32367461c1ec75ed9060bee430c6b7
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Fibroblasts\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NES ADAMTS1 NUDT6 ECEL1 SLC4A4	2.54e-05	157	98	5	f086753b51860e23f1275bd75e8802d2a7d7b70a
ToppCell	RV-13._Vascular_Smooth_Muscle\|RV / Chamber and Cluster_Paper	DGKH KCNA5 ANTXR1 EGFLAM SLC22A31	2.86e-05	161	98	5	47b3b7662cbb671ccc086dc0a0cabd65f63eb5a1
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-Pericytes-Immature_pericyte\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DGKH ADAM22 PTK2 EGFLAM EPHA3	3.22e-05	165	98	5	3d14f37b8a9c0ddc1130e60a2e08556bad1fb855
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NES DGKH GRK3 LRP1 SLC4A4	3.71e-05	170	98	5	5570c0e825bca77613bf0ebde620cf744fa1cb84
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTS12 LRP1 ANTXR1 HHIPL1 EPHA3	4.26e-05	175	98	5	795a6564d5a75ffd35d39f5274b9e8d28708bbc8
ToppCell	tumor_Lymph_Node_/_Brain-Fibroblasts-Pericytes\|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass	ADAMTS1 ADAMTS12 KCNA5 EGFLAM EPHA3	4.38e-05	176	98	5	2015539c58aa0bb118e111ffedd63dd9fe863bb1
ToppCell	droplet-Spleen-nan-21m-Lymphocytic-mature_NK_T_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPN18 ZAP70 CAMK2N1 CD6 EPHA3	4.50e-05	177	98	5	1381aeb48a4133af060a9e2e7ce08b8b058e12c1
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Rectal_Adenocarcinoma-7\|TCGA-Colorectal / Sample_Type by Project: Shred V9	NES LAMC1 ANTXR1 GARRE1 EPHA3	4.62e-05	178	98	5	edc76b8f15056ec1c9a1c61a048b6331a92592d6
ToppCell	COPD-Stromal-SMC\|COPD / Disease state, Lineage and Cell class	NES ADAMTS1 CAMK2N1 KCNA5 ANTXR1	4.75e-05	179	98	5	5c705627bd13a5b2c7b0062fb3d94e4eb1589327
ToppCell	Control-Stromal-SMC\|Control / Disease state, Lineage and Cell class	NES ADAMTS1 CAMK2N1 KCNA5 ANTXR1	4.75e-05	179	98	5	1378051bc62009eec2dbecf3d5d89baedbeb84eb
ToppCell	COVID-19-Heart-Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ADAMTS1 ADAMTS12 EGFLAM EPHA3 PDZD2	5.00e-05	181	98	5	33cac65ed1ea5e7bd72250495df4f850b143d5aa
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NES PATZ1 IQSEC2 TIGD5 PCSK4	5.00e-05	181	98	5	709e9c7a60d5f98635b99895ce30bb87a9f7376d
ToppCell	droplet-Liver-Npc-21m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHB4 ADAM23 ARHGEF15 NTN5 GARRE1	5.13e-05	182	98	5	b1ec2015aad1181eac1bbf8d48ad6f2f7ed24a01
ToppCell	LPS_only-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ADAM22 ADAMTS12 ANTXR1 SLC4A4 EPHA3	5.27e-05	183	98	5	12daaea821e49bc94a01e2496331e92a80d27339
ToppCell	COVID-19-Heart-Pericyte\|Heart / Disease (COVID-19 only), tissue and cell type	ADAMTS1 ADAMTS12 EGFLAM EPHA3 PDZD2	5.41e-05	184	98	5	21790cdfa3b4036ad413fd44b94e31563116f25f
ToppCell	5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ADAMTS1 AOX1 LAMC1 LRP1 EGFLAM	5.55e-05	185	98	5	9faa35ceb89ccd2979072286f063687c9f846ce3
ToppCell	pdx-Tumor_cells-T0\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	AOX1 PTK2 ELL2 FBXO31 LRP1	5.55e-05	185	98	5	1d874608aa2062024323512f68889219471b2f00
ToppCell	Smart-seq2-lymph_node_(Smart-seq2)-lymphocytic-T_lymphocytic-effector_CD4-positive,_alpha-beta_T_cell\|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	ACSL6 ADAM23 DGKH ZAP70 CD6	5.84e-05	187	98	5	e61c1755531469dd3850c9740474b5ad4e0499c1
ToppCell	Pericytes-HP_01\|World / lung cells shred on cell class, cell subclass, sample id	NES CAND2 ADAMTS12 KCNA5 EGFLAM	5.84e-05	187	98	5	35f25780d113f60bf4c13749013c09612ee4ff41
ToppCell	Control-Fibroblasts-Adventitial_FB\|Control / group, cell type (main and fine annotations)	EPHA6 ADAMTS1 AOX1 LRP1 EPHA3	5.99e-05	188	98	5	706a26c372add839d947749f0521a0e1f5c9b0ec
ToppCell	10x3'2.3-week_17-19-Mesenchymal_osteo-stroma-osteochondral_precursor\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	ADAMTS1 CAMK2N1 ANTXR1 EGFLAM EPHA3	6.14e-05	189	98	5	1ff4f8da572bdc6356e9df9f41a7f62c81d4c570
ToppCell	facs-Trachea-3m-Hematologic-lymphocytic-T_cell-T_cell_of_trachea\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PATZ1 PTPN18 ZAP70 CD6 KIFC1	6.14e-05	189	98	5	286fcf22a2766cf435cd22f0986b1ca007d5b75a
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	AOX1 ADAMTS12 CAMK2N1 LRP1 ANTXR1	6.14e-05	189	98	5	a153b83314cf52808f685296cff8c95af3f4983d
ToppCell	droplet-Lung-LUNG-30m-Endothelial\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHB4 NES ADAMTS1 ARHGEF15 GARRE1	6.14e-05	189	98	5	25db316f66cee53774bb2b286cc457b37353356c
ToppCell	facs-Trachea-3m-Hematologic-lymphocytic\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PATZ1 PTPN18 ZAP70 CD6 KIFC1	6.14e-05	189	98	5	815631878564b805f3dc30877c5804c3ddb8641b
ToppCell	facs-Trachea-3m-Hematologic-lymphocytic-T_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PATZ1 PTPN18 ZAP70 CD6 KIFC1	6.14e-05	189	98	5	035e5af872fcb8b527fa85dbcaa56e3aaff24531
ToppCell	droplet-Lung-LUNG-30m-Endothelial-endothelial_cell_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHB4 NES ADAMTS1 ARHGEF15 GARRE1	6.30e-05	190	98	5	e64b191f928935484e2c993d7f8af0572a617a3a
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	AOX1 ADAMTS12 CAMK2N1 LRP1 ANTXR1	6.30e-05	190	98	5	841cd55861b43578d704418b9bc0af2e8b88323a
ToppCell	E15.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_myogenic_precursor_(Axin2+)\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	NES PTK2 CAMK2N1 EGFLAM PDZD2	6.30e-05	190	98	5	84fbd5664ec886120963d4f50dfa1fd1851d36c1
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ADAMTS1 AOX1 LAMC1 LRP1 EGFLAM	6.45e-05	191	98	5	4e4488380379ed29d7898bae4e24221e7c67eb9d
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	AOX1 ADAMTS12 CAMK2N1 LRP1 ANTXR1	6.61e-05	192	98	5	6f4ef24dab544681304b7f8a9dc073e7edaa4cf5
ToppCell	facs-Trachea-3m-Mesenchymal-fibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ADAMTS1 LAMC1 CAMK2N1 LRP1 ANTXR1	6.61e-05	192	98	5	321850b0f881420c2d57d3e825e365c82fa511ab
ToppCell	Epithelial-alveolar_epithelial_cell_type_2\|World / Lineage, Cell type, age group and donor	ABCA3 DMBT1 SLC4A4 PDZD2 SLC22A31	6.61e-05	192	98	5	58c3737be7acce39fd2b91d70d6d7b2bbaa4f710
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	AOX1 ADAMTS12 CAMK2N1 LRP1 ANTXR1	6.61e-05	192	98	5	dcd924d6eb67d33ee9f5d3e8ab6e1d4283d6b708
ToppCell	LPS_only-Stromal_mesenchymal\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ADAMTS1 AOX1 CAMK2N1 LRP1 ANTXR1	6.61e-05	192	98	5	162d8b5858d150ecbbd1c9bf2b19c6c9cd50a158
ToppCell	facs-Lung-nan-3m-Endothelial-Capillary_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHB4 ADAMTS1 DGKH ARHGEF15 GARRE1	6.61e-05	192	98	5	4bab9754cfd8b9c2d7cc1490e8a29f58c3c26f6c
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ABCA3 DMBT1 SLC4A4 PDZD2 SLC22A31	6.61e-05	192	98	5	fb2f0e897228f808d9ff734ad05e9b49dc38fa50
ToppCell	facs-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ADAMTS1 LAMC1 CAMK2N1 LRP1 ANTXR1	6.61e-05	192	98	5	cf2765d8bc074f7f9ee864eae632a3b705175842
ToppCell	facs-MAT-Fat-3m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTS1 LAMC1 LRP1 ANTXR1 EGFLAM	6.78e-05	193	98	5	f95b95c58a6edb8a03dd15ae166f47f9f33d8bd6
ToppCell	droplet-Lung-nan-21m-Endothelial-Capillary_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHB4 NES ADAMTS1 ARHGEF15 GARRE1	6.78e-05	193	98	5	4893b922e129711d5886bd4f3ee106e9e7065971
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2\|Adult / Lineage, Cell type, age group and donor	ABCA3 DMBT1 SLC4A4 PDZD2 SLC22A31	6.78e-05	193	98	5	738f4f0a9ddde2432b429ab46838e353b1790589
ToppCell	facs-MAT-Fat-3m-Mesenchymal-mesenchymal_progenitor\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTS1 LAMC1 LRP1 ANTXR1 EGFLAM	6.78e-05	193	98	5	85faf6c5ce4769615a4eca036e2ba307e176bb52
ToppCell	facs-MAT-Fat-3m-Mesenchymal\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTS1 LAMC1 LRP1 ANTXR1 EGFLAM	6.78e-05	193	98	5	110a7d2ba7d066c2be38be98b643b76c520dd980
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	ADAM22 ADAMTS12 GRK3 ANTXR1 SLC4A4	6.95e-05	194	98	5	b1bb0f846d2865efdd9bc8842b16b9d069785882
ToppCell	droplet-Lung-21m-Endothelial\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	EPHB4 NES ADAMTS1 ARHGEF15 GARRE1	6.95e-05	194	98	5	b45aebbc7641df0bf56d0c2e88821f1daf705449
ToppCell	facs-Lung-nan-3m-Endothelial-endothelial_cell_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHB4 ADAMTS1 DGKH ARHGEF15 GARRE1	6.95e-05	194	98	5	f159ef8541d75a4e98468947f231bb463bec922c
ToppCell	LV-14._Fibroblast_III\|LV / Chamber and Cluster_Paper	ADAMTS1 AOX1 ELL2 ANTXR1 EIF2AK3	6.95e-05	194	98	5	927c26aea0147f7a4b8fb3f192de4de263f1b978
ToppCell	droplet-Lung-18m-Endothelial-capillary_endothelial-capillary_endothelial_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	EPHB4 NES ADAMTS1 ARHGEF15 GARRE1	6.95e-05	194	98	5	ff076902578997565d72dc40b0b80ae76d6ab2b4
ToppCell	droplet-Lung-18m-Endothelial-capillary_endothelial\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	EPHB4 NES ADAMTS1 ARHGEF15 GARRE1	6.95e-05	194	98	5	627432da2e00dc4256f48a6388ce78e7b5e7a51e
ToppCell	droplet-Fat-Scat-18m-Endothelial-Cd36+\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHB4 NES ARHGEF15 KCNA5 GARRE1	6.95e-05	194	98	5	009b005a94a5c80f6e1fdda2a0c7881a9a0ce75b
ToppCell	droplet-Lung-18m-Endothelial\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	EPHB4 NES ADAMTS1 ARHGEF15 GARRE1	6.95e-05	194	98	5	fd4548db0f12170b636186e6af90666f7e26c0ad
ToppCell	droplet-Liver-LIVER-NPC-1m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHB4 ADAMTS1 ADAM23 ARHGEF15 GARRE1	7.12e-05	195	98	5	126f46dd15dddcf5701144718bb8ba1ce84b2d1d
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	ADAM22 ADAMTS12 GRK3 ANTXR1 SLC4A4	7.12e-05	195	98	5	0e55fa5b3cbeb7baee3d4ac272a3bf80381ec937
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	AOX1 LAMC1 ADAMTS12 CAMK2N1 LRP1	7.12e-05	195	98	5	df409f94f4e83be89f7a608058ee07ce3ce3a149
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	LAMC1 ADAMTS12 CAMK2N1 LRP1 EPHA3	7.12e-05	195	98	5	1236dc60288c7dd91868e86e9174a2dacd3b11b3
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Pericyte-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	LAMC1 ADAMTS12 ANTXR1 EGFLAM EPHA3	7.12e-05	195	98	5	d760d1423f9a8a373fe7b250ea9b1d67a0c0059f
ToppCell	PCW_05-06-Mesenchymal\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	ADAMTS12 CAMK2N1 ANTXR1 SLC4A4 EPHA3	7.29e-05	196	98	5	dca52c57ba35d9395cdbca8b881f12ece721b10f
ToppCell	COPD-Stromal-Myofibroblast\|COPD / Disease state, Lineage and Cell class	ADAMTS1 AOX1 LAMC1 CAMK2N1 ANTXR1	7.29e-05	196	98	5	af206bb5bbb8b604a6212acd79878bcc3d326cec
ToppCell	Bronchial-NucSeq-Stromal-Schwann-Schwann_Myelinating\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	NES ABAT EPHA6 CELSR2 PLOD1	7.29e-05	196	98	5	efeb272bc9e37e60d15d056b7574991c5c7501bc
ToppCell	PCW_07-8.5-Mesenchymal\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	ADAMTS12 CAMK2N1 LRP1 ANTXR1 SLC4A4	7.29e-05	196	98	5	8e10802f52e5e1853ea4ad34bf9a32a34e6112b5
ToppCell	facs-Liver-Liver_non-hepato/SCs-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHB4 ADAMTS1 ADAM23 ARHGEF15 GARRE1	7.29e-05	196	98	5	81900dcc9451ff6606ec940c16b559d73247590e
ToppCell	IPF-Stromal-Myofibroblast\|IPF / Disease state, Lineage and Cell class	LAMC1 ADAMTS12 CAMK2N1 ANTXR1 EPHA3	7.29e-05	196	98	5	2d0a48e49b3b37bb66e33e74c52915911e1f8a74
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	AOX1 LAMC1 ADAMTS12 CAMK2N1 LRP1	7.29e-05	196	98	5	42e9828222a9663525d571633e8a454c30bfa7f8
ToppCell	T_cells-CD56_dim_CD16+_NK_cells\|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis	ADAMTS1 PTPN18 ADAM8 FURIN PLOD1	7.29e-05	196	98	5	07b557b8530c19ca5b31ad2eac00c36ef1939266
ToppCell	droplet-Heart-HEART-1m-Hematologic-red_blood_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA3 KCTD1 NUDT6 KIFC1	7.35e-05	101	98	4	6c4524be89cf3eb06769c2963dcded3da1e71ca0
ToppCell	facs-Liver-Non-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHB4 ADAMTS1 ADAM23 ARHGEF15 GARRE1	7.47e-05	197	98	5	deefb492b5f0e6014144bd465c4a6ae4206e8739
ToppCell	COPD-Stromal-Myofibroblast\|World / Disease state, Lineage and Cell class	ADAMTS1 LAMC1 ADAMTS12 CAMK2N1 ANTXR1	7.47e-05	197	98	5	d51f484b4e01ac64233950d0b97fa88825ea1dbb
ToppCell	mild-low-quality_cells\|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	DGKH ZAP70 ADAM22 CACNA1I SLC4A4	7.47e-05	197	98	5	e4331969bd911d1ebb5453f40a7057297b5389b4
ToppCell	facs-Liver-Non-hepatocytes-3m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHB4 ADAMTS1 ADAM23 ARHGEF15 GARRE1	7.47e-05	197	98	5	a6aaa6faea348291023f0bc4b0f83fbc67d91da6
ToppCell	PCW_13-14-Mesenchymal\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	ADAMTS12 CAMK2N1 LRP1 ANTXR1 SLC4A4	7.47e-05	197	98	5	73a2085d2682d636726a5432d572ae2a3fbe1c3f
ToppCell	5'-GW_trimst-2-SmallIntestine-Mesenchymal-Pericytes-Immature_pericyte\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DGKH PTK2 ADAMTS12 KCNA5 EGFLAM	7.47e-05	197	98	5	fd65a9b41df618ff2a09d76dcf9f1ca3f3bdf52a
ToppCell	COPD-Stromal\|COPD / Disease state, Lineage and Cell class	ADAMTS1 AOX1 LAMC1 CAMK2N1 ANTXR1	7.47e-05	197	98	5	d5390d86acaa8c39f1da893e8d2271f9ed2951d7
ToppCell	390C-Endothelial_cells-Endothelial-A_(Artery)-\|390C / Donor, Lineage, Cell class and subclass (all cells)	EPHB4 NES ADAM23 ARHGEF15 GARRE1	7.65e-05	198	98	5	f83956c4b13b5d0a0c6e3d9f580dbf99649ef175
ToppCell	ILEUM-inflamed-(8)_Fibroblast-(8)_Pericytes\|(8)_Fibroblast / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	ADAMTS1 PTK2 KCNA5 EGFLAM ECEL1	7.65e-05	198	98	5	5e274c5597d8720290d452465f0bd40637cb3f27
ToppCell	IPF-Stromal\|IPF / Disease state, Lineage and Cell class	ADAMTS1 AOX1 LAMC1 CAMK2N1 ANTXR1	7.65e-05	198	98	5	ece914c32c9b123b779aa9624b92e6230763a20e
ToppCell	facs-Liver-Non-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHB4 ADAMTS1 ADAM23 ARHGEF15 GARRE1	7.65e-05	198	98	5	f0f1816a0ed3ae8207442602f5cbe4de0382e4b3
ToppCell	cellseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ADAMTS1 AOX1 LAMC1 ADAMTS12 CAMK2N1	7.65e-05	198	98	5	f1374f7a50244d59c766ac41f44c08c9117407d2
ToppCell	390C-Endothelial_cells-Endothelial-A_(Artery)\|390C / Donor, Lineage, Cell class and subclass (all cells)	EPHB4 NES ADAM23 ARHGEF15 GARRE1	7.65e-05	198	98	5	5b5ccce5de82ea041465e656147cec3b8beb865b
ToppCell	mild-Plasmablast\|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	NES PAOX ELL2 EIF2AK3 TP73	7.65e-05	198	98	5	b14b9e67815f93fac7bd8e5e6f1aa100951b4ac1
ToppCell	Biopsy_Other_PF-Epithelial-AT2\|Biopsy_Other_PF / Sample group, Lineage and Cell type	ABCA3 DMBT1 SLC4A4 PDZD2 SLC22A31	7.83e-05	199	98	5	9a65acfe9bf500db72142469cf17bf0973540001
Drug	Flurandrenolide [1524-88-5]; Up 200; 9.2uM; MCF7; HT_HG-U133A	CAND2 GRM6 ADAM8 ADAM22 HOXA1 KCNA5 CACNA1I DMBT1 SLC4A4	1.68e-07	195	98	9	6039_UP
Drug	Stachydrine hydrochloride; Up 200; 22.2uM; MCF7; HT_HG-U133A	CAND2 ADAM23 SH3D21 CD6 GRK2 WNT16 HHIPL2 CACNA1I SLC4A4	1.83e-07	197	98	9	6805_UP
Drug	Delcorine; Down 200; 8.4uM; MCF7; HT_HG-U133A	RCHY1 IQSEC2 AOC2 SMURF1 CHRNB2 TAOK2 PAOX ANTXR1 CACNA1I	2.00e-07	199	98	9	6033_DN
Drug	dl-Lysine	NES ABAT LAMC1 AASDH PTK2 MRPL2 TAOK2 PAOX BTD PLOD1	5.02e-07	290	98	10	CID000000866
Drug	Norgestrel-(-)-D [797-63-7]; Up 200; 12.8uM; PC3; HT_HG-U133A	CD163 SBNO2 CD6 WNT16 LRP1 CACNA1I ECEL1 EPHA3	1.97e-06	194	98	8	4269_UP
Drug	Crotamiton [483-63-6]; Down 200; 19.6uM; PC3; HT_HG-U133A	IQSEC2 SMURF1 PTPN18 HOXA1 TAOK2 CD6 FURIN CACNA1I	2.12e-06	196	98	8	4628_DN
Drug	Pivampicillin [33817-20-8]; Up 200; 8.6uM; PC3; HT_HG-U133A	ATP9B CHRNB2 ADAMTS12 GRK3 WNT16 LRP1 CACNA1I DMBT1	2.20e-06	197	98	8	5046_UP
Drug	(S)-(-)-Atenolol [93379-54-5]; Up 200; 15uM; HL60; HT_HG-U133A	ABAT SMURF1 TAOK2 FBXO22 BTD LRP1 ANTXR1 CACNA1I	2.29e-06	198	98	8	3067_UP
Drug	Ethosuximide [77-67-8]; Down 200; 28.4uM; PC3; HT_HG-U133A	EPHB4 PTPN18 SESN1 AHDC1 SBNO2 MRPL2 TAOK2 BTD	2.47e-06	200	98	8	7308_DN
Drug	Folinic acid calcium salt [6035-45-6]; Down 200; 7.8uM; MCF7; HT_HG-U133A	SMURF1 PTPN18 ADAM8 ADAM22 PAOX MZF1 ZNF74 EPHA3	2.47e-06	200	98	8	3442_DN
Drug	gamma-aminobutyraldehyde	ABAT AOC2 AASDH PAOX	3.81e-06	25	98	4	CID000000118
Drug	N-methyl-DL-aspartic acid	SHANK1 GRM6 ADAM22 PTK2 CHRNB2 GRK2 GRK3 LRP1 CACNA1I PLOD1 NANOS1 EIF2AK3 EPHA3	4.68e-06	655	98	13	CID000004376
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; PC3; HT_HG-U133A	CAND2 RCHY1 PATZ1 SBNO2 SETD2 MZF1 TLCD3A	1.30e-05	180	98	7	6886_DN
Drug	Metanephrine hydrochloride DL [881-95-8]; Up 200; 17.2uM; PC3; HT_HG-U133A	GRM6 SH3D21 CHRNB2 TAOK2 GRK3 WNT16 DMBT1	1.97e-05	192	98	7	6734_UP
Drug	troglitazone; Down 200; 10uM; PC3; HG-U133A	AOX1 ADAM8 CHRNB2 SBNO2 TAOK2 MZF1 CACNA1I	2.04e-05	193	98	7	431_DN
Drug	rosiglitazone; Down 200; 10uM; PC3; HT_HG-U133A	ADAMTS1 SMURF1 ATP9B AHDC1 HOXA1 MZF1 PDZD2	2.04e-05	193	98	7	1233_DN
Drug	Salsolinol hydrobromide [38221-21-5]; Down 200; 15.4uM; PC3; HT_HG-U133A	ABCA3 ADAM22 TAOK2 GRK2 BTD LRP1 SLC4A4	2.10e-05	194	98	7	4232_DN
Drug	Pentolinium bitartrate [52-62-0]; Up 200; 7.4uM; PC3; HT_HG-U133A	SHANK1 ADAM23 ADAM8 SH3D21 GRK2 CACNA1I ECEL1	2.10e-05	194	98	7	3676_UP
Drug	Megestrol acetate [595-33-5]; Down 200; 10.4uM; PC3; HT_HG-U133A	ADAM23 IQSEC2 ADAM8 HOXA1 CD6 GRK2 LRP1	2.10e-05	194	98	7	6667_DN
Drug	5252917; Down 200; 14uM; MCF7; HT_HG-U133A_EA	SMURF1 PTPN18 TAOK2 FBXO22 CD6 MZF1 EIF2AK3	2.17e-05	195	98	7	828_DN
Drug	Mebhydroline 1,5-naphtalenedisulfonate [6153-33-9]; Down 200; 4.8uM; MCF7; HT_HG-U133A	IQSEC2 ATP9B ADAM22 PAOX FBXO22 MZF1 SLC4A4	2.17e-05	195	98	7	3269_DN
Drug	Deoxycorticosterone [64-85-7]; Up 200; 12.2uM; HL60; HT_HG-U133A	ADAM22 HOXA1 ADAMTS12 PAOX GRK2 BTD SLC4A4	2.17e-05	195	98	7	3099_UP
Drug	Finasteride [98319-26-7]; Down 200; 10.8uM; PC3; HT_HG-U133A	EPHB4 SMURF1 ATP9B GRM6 SBNO2 TAOK2 GRK3	2.17e-05	195	98	7	4300_DN
Drug	Molindone hydrochloride [15622-65-8]; Down 200; 12.8uM; MCF7; HT_HG-U133A	SMURF1 AHDC1 SETD2 FBXO22 MZF1 FURIN PLOD1	2.17e-05	195	98	7	4784_DN
Drug	Ethoxyquin [91-53-2]; Up 200; 18.4uM; PC3; HT_HG-U133A	IQSEC2 ATP9B HOXA1 PAOX WNT16 CACNA1I DMBT1	2.25e-05	196	98	7	4321_UP
Drug	Gabazine [105538-73-6]; Down 200; 10.8uM; PC3; HT_HG-U133A	ADAM22 SBNO2 TAOK2 CD6 GRK2 GRK3 CELSR2	2.25e-05	196	98	7	4236_DN
Drug	Sulfasalazine [599-79-1]; Down 200; 10uM; MCF7; HT_HG-U133A	SMURF1 ADAM22 TAOK2 GRK3 BTD FURIN SLC4A4	2.25e-05	196	98	7	5446_DN
Drug	Carisoprodol [78-44-4]; Down 200; 15.4uM; MCF7; HT_HG-U133A	EPHB4 PTPN18 AHDC1 ADAM22 NECAP2 GRK2 MZF1	2.25e-05	196	98	7	3251_DN
Drug	Tranexamic acid [1197-18-8]; Down 200; 25.4uM; MCF7; HT_HG-U133A	EPHB4 SMURF1 PEX14 MRPL2 TAOK2 GRK3 BTD	2.25e-05	196	98	7	6238_DN
Drug	Saquinavir mesylate [149845-06-7]; Up 200; 5.2uM; PC3; HT_HG-U133A	ADAM22 SBNO2 TAOK2 CD6 WNT16 LRP1 CACNA1I	2.32e-05	197	98	7	5770_UP
Drug	Clebopride maleate [84370-95-6]; Up 200; 8.2uM; PC3; HT_HG-U133A	AOC2 FBXO11 SBNO2 HOXA1 NUDT6 CELSR2 BTD	2.32e-05	197	98	7	6311_UP
Drug	Sulfadiazine [68-35-9]; Down 200; 16uM; PC3; HT_HG-U133A	UBR2 ABCA3 CAND2 ADAMTS1 PTPN18 GRK2 BTD	2.32e-05	197	98	7	5098_DN
Drug	Merbromin [129-16-8]; Down 200; 5uM; MCF7; HT_HG-U133A	AOX1 SMURF1 PEX14 ADAM8 ADAM22 PAOX GRK2	2.32e-05	197	98	7	3439_DN
Drug	Pindolol [13523-86-9]; Up 200; 16.2uM; PC3; HT_HG-U133A	CAND2 ADAMTS1 IQSEC2 AOX1 LRP1 DMBT1 SLC4A4	2.32e-05	197	98	7	2075_UP
Drug	Dimethadione [695-53-4]; Down 200; 31uM; MCF7; HT_HG-U133A	EPHB4 RCHY1 ADAM22 FBXO22 CD6 GRK3 FURIN	2.32e-05	197	98	7	5668_DN
Drug	Ethamivan [304-84-7]; Up 200; 18uM; MCF7; HT_HG-U133A	SHANK1 ADAM23 ADAM22 SBNO2 PAOX ANTXR1 ZNF74	2.32e-05	197	98	7	7021_UP
Drug	Azaperone [1649-18-9]; Up 200; 12.2uM; MCF7; HT_HG-U133A	ADAM23 IQSEC2 GRM6 ADAM22 CHRNB2 GRK2 KCNA5	2.32e-05	197	98	7	3573_UP
Drug	Idoxuridine [54-42-2]; Down 200; 11.2uM; MCF7; HT_HG-U133A	LAMC1 ADAM8 SBNO2 SETD2 FBXO22 MZF1 BTD	2.40e-05	198	98	7	4785_DN
Drug	Dihydroergocristine mesylate [24730-10-7]; Down 200; 5.6uM; MCF7; HT_HG-U133A	IQSEC2 SMURF1 PEX14 ADAM22 NECAP2 GRK2 GRK3	2.40e-05	198	98	7	7034_DN
Drug	Glycopyrrolate [596-51-0]; Down 200; 10uM; MCF7; HT_HG-U133A	AOX1 ATP9B ADAM8 ADAM22 SBNO2 PAOX MZF1	2.40e-05	198	98	7	3427_DN
Drug	(+) -Levobunolol hydrochloride [47141-41-3]; Up 200; 12.2uM; PC3; HT_HG-U133A	PTPN18 AHDC1 ADAM22 HOXA1 TAOK2 CD6 GRK3	2.40e-05	198	98	7	6635_UP
Drug	Captopril [62571-86-2]; Up 200; 17.2uM; PC3; HG-U133A	PATZ1 SMURF1 LAMC1 GRM6 CELSR2 MZF1 BTD	2.40e-05	198	98	7	1907_UP
Drug	Hymecromone [90-33-5]; Down 200; 22.8uM; MCF7; HT_HG-U133A	EPHB4 NES FBXO11 AHDC1 ADAM22 PAOX EPHA3	2.40e-05	198	98	7	5684_DN
Drug	Folinic acid calcium salt [6035-45-6]; Up 200; 7.8uM; PC3; HT_HG-U133A	PATZ1 PTPN18 ZAP70 GRK2 GRK3 LRP1 ANTXR1	2.40e-05	198	98	7	3703_UP
Drug	Methantheline bromide [53-46-3]; Up 200; 9.6uM; MCF7; HT_HG-U133A	ADAM23 ADAM8 AHDC1 ADAM22 CHRNB2 GRK2 DMBT1	2.40e-05	198	98	7	6254_UP
Drug	Neostigmine bromide [114-80-7]; Down 200; 13.2uM; MCF7; HT_HG-U133A	EPHB4 NES PTPN18 TAOK2 BTD FURIN SLC4A4	2.40e-05	198	98	7	5335_DN
Drug	CP-319743 [172078-87-4]; Up 200; 10uM; MCF7; HT_HG-U133A	SHANK1 EPHB4 ADAM8 ADAM22 CD6 CACNA1I DMBT1	2.48e-05	199	98	7	7532_UP
Drug	Corticosterone [50-22-6]; Down 200; 11.6uM; PC3; HT_HG-U133A	IQSEC2 SMURF1 CELSR2 FURIN LRP1 ZNF74 CACNA1I	2.48e-05	199	98	7	4064_DN
Drug	2-propylpentanoic acid; Down 200; 2000uM; MCF7; HG-U133A	PATZ1 SMURF1 SBNO2 CD6 MZF1 ZNF74 SLC4A4	2.48e-05	199	98	7	346_DN
Drug	tolbutamide; Down 200; 100uM; MCF7; HG-U133A	ADAM23 ADAM22 ARHGEF15 PAOX CACNA1I DMBT1 SLC4A4	2.48e-05	199	98	7	142_DN
Drug	(-) -Levobunolol hydrochloride [27912-14-7]; Down 200; 12.2uM; PC3; HT_HG-U133A	ADAMTS1 IQSEC2 SMURF1 GRM6 ADAM22 SH3D21 CACNA1I	2.48e-05	199	98	7	4016_DN
Drug	Trolox [53188-07-1]; Down 200; 16uM; MCF7; HT_HG-U133A	RCHY1 SMURF1 FBXO11 SBNO2 MRPL2 GRK2 EPHA3	2.48e-05	199	98	7	2883_DN
Drug	aspirin, USP; Up 200; 100uM; HL60; HT_HG-U133A	NES ABAT ADAM22 SH3D21 SBNO2 CACNA1I PDZD2	2.48e-05	199	98	7	6164_UP
Drug	Niflumic acid [4394-00-7]; Down 200; 14.2uM; HL60; HT_HG-U133A	ADAMTS1 PATZ1 AHDC1 SETD2 CD6 FURIN SLC4A4	2.48e-05	199	98	7	2399_DN
Drug	1,1-dimethylbiguanide hydrochloride; Up 200; 10uM; MCF7; HG-U133A	NES AOC2 FBXO11 ARHGEF15 SBNO2 CD6 SLC4A4	2.48e-05	199	98	7	1_UP
Drug	Sisomicin sulfate [53179-09-2]; Down 200; 2.8uM; PC3; HT_HG-U133A	GRM6 PTPN18 ADAM8 ADAM22 SH3D21 TAOK2 CD6	2.56e-05	200	98	7	4014_DN
Drug	Isometheptene mucate; Up 200; 8.2uM; MCF7; HT_HG-U133A	CAND2 RCHY1 ADAM8 ADAM22 FBXO22 MZF1 DMBT1	2.56e-05	200	98	7	5502_UP
Drug	N1-acetylspermine	ABAT AOC2 PAOX	2.72e-05	14	98	3	CID000000916
Drug	EKB-569	EPHB4 EPHA6 PTK2 EIF2AK3 EPHA3	3.73e-05	87	98	5	CID006445562
Drug	MDL 72527	ABAT AOC2 PAOX	4.16e-05	16	98	3	CID000004026
Drug	Mecamylamine	ACSL6 CHRNB2 KMT2C EIF2AK3	4.58e-05	46	98	4	ctd:D008464
Drug	methylimidazole acetaldehyde	AOC2 AOX1 AASDH	5.03e-05	17	98	3	CID000193545
Drug	acisoga	AOC2 PAOX	5.49e-05	3	98	2	CID000129397
Drug	KN-62	GRM6 PTK2 GRK2 GRK3 SLC4A4 NANOS1 EIF2AK3	6.22e-05	230	98	7	CID000003838
Drug	agmatine	ABAT AOC2 GRM6 PAOX NANOS1	7.98e-05	102	98	5	CID000000199
Drug	genistein	EPHB4 LAMC1 SESN1 ZAP70 PTK2 PAOX SETD2 NUDT6 GRK2 GRK3 KCNA5 FURIN CACNA1I PLOD1 NANOS1	8.34e-05	1117	98	15	CID005280961
Drug	N1-acetylspermidine	ABAT AOC2 PAOX	8.36e-05	20	98	3	CID000000496
Drug	2,4-diaminopyrimidine	AOX1 LAMC1 PTK2 FURIN	8.65e-05	54	98	4	CID000067431
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	PATZ1 SBNO2 FBXO22 CACNA1I SLC4A4 TLCD3A	9.16e-05	169	98	6	6064_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	PATZ1 PEX14 PTPN18 SBNO2 MZF1 TLCD3A	1.01e-04	172	98	6	4112_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A	CAND2 PATZ1 SMURF1 PEX14 SBNO2 TLCD3A	1.08e-04	174	98	6	3993_DN
Drug	spermic acid	AOC2 PAOX	1.09e-04	4	98	2	CID000167029
Drug	Sp-8-Cl-cAMPS	NUDT6 GRK2 GRK3	1.12e-04	22	98	3	CID000133987
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	RCHY1 PATZ1 PTPN18 SBNO2 MZF1 TLCD3A	1.22e-04	178	98	6	4710_DN
Drug	15d-PGJ2; Down 200; 10uM; HL60; HT_HG-U133A	EPHB4 PATZ1 NUDT6 GRK2 MZF1 ZNF74	1.46e-04	184	98	6	2691_DN
Drug	zonisamide	ABAT AOX1 CACNA1I NANOS1	1.49e-04	62	98	4	CID000005734
Drug	Mepenzolate bromide [76-90-4]; Down 200; 9.6uM; MCF7; HT_HG-U133A	RCHY1 SMURF1 ATP9B ADAM22 TAOK2 MZF1	1.79e-04	191	98	6	6024_DN
Drug	geranylamine	AOC2 PAOX	1.82e-04	5	98	2	CID000160248
Drug	N(8)-(2-carboxyethyl)spermidine	AOC2 PAOX	1.82e-04	5	98	2	CID000125245
Drug	perhydroazepinyl	AOC2 AOX1	1.82e-04	5	98	2	CID000123152
Drug	4-methylquinoline	AOX1 PAOX	1.82e-04	5	98	2	CID000010285
Drug	15d-PGJ2; Down 200; 10uM; MCF7; HT_HG-U133A	PATZ1 AOX1 FBXO11 PTPN18 CAMK2N1 EPHA3	1.84e-04	192	98	6	6990_DN
Drug	Tiletamine hydrochloride; Down 200; 15.4uM; MCF7; HT_HG-U133A	PATZ1 SMURF1 SBNO2 TAOK2 FBXO22 GARRE1	1.84e-04	192	98	6	6013_DN
Drug	tyrphostin 25	ZAP70 PTK2 GRK2 GRK3 KCNA5	1.86e-04	122	98	5	CID000002061
Drug	carbamazepine; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA	PATZ1 AOX1 SBNO2 GRK2 GRK3 EPHA3	1.89e-04	193	98	6	835_DN
Drug	Mexiletine hydrochloride [5370-01-4]; Down 200; 18.6uM; PC3; HT_HG-U133A	PATZ1 FBXO11 AHDC1 SBNO2 GRK3 FURIN	1.89e-04	193	98	6	4338_DN
Drug	Zidovudine, AZT [30516-87-1]; Down 200; 15uM; PC3; HT_HG-U133A	ADAM23 PEX14 ADAM8 AHDC1 SBNO2 LRP1	1.89e-04	193	98	6	6733_DN
Drug	Tiaprofenic acid [33005-95-7]; Down 200; 15.4uM; MCF7; HT_HG-U133A	AOX1 GRM6 ADAM22 CD6 BTD WNT16	1.95e-04	194	98	6	4171_DN
Drug	Tocopherol (R,S) [10191-41-0]; Down 200; 9.2uM; PC3; HT_HG-U133A	ABCA3 IQSEC2 AOC2 SBNO2 GRK2 LRP1	1.95e-04	194	98	6	6616_DN
Drug	genistein; Up 200; 10uM; MCF7; HT_HG-U133A_EA	ABAT PEX14 SESN1 CELSR2 MZF1 BTD	1.95e-04	194	98	6	1073_UP
Drug	5194442; Up 200; 20uM; PC3; HT_HG-U133A	IQSEC2 AOC2 PTPN18 AHDC1 SBNO2 SLC4A4	1.95e-04	194	98	6	6553_UP
Drug	rosiglitazone maleate; Down 200; 10uM; PC3; HG-U133A	ADAMTS1 AHDC1 TAOK2 MZF1 ANTXR1 CACNA1I	1.95e-04	194	98	6	430_DN
Drug	Terconazole [67915-31-5]; Up 200; 7.6uM; MCF7; HT_HG-U133A	ADAM23 IQSEC2 ATP9B ADAM22 GRK2 CACNA1I	1.95e-04	194	98	6	2844_UP
Drug	Clobetasol propionate [25122-46-7]; Up 200; 8.6uM; MCF7; HT_HG-U133A	EPHB4 ADAM23 AHDC1 ADAM22 SBNO2 PAOX	1.95e-04	194	98	6	6835_UP
Drug	(-)-Isoproterenol hydrochloride [5984-95-2]; Up 200; 16.2uM; MCF7; HT_HG-U133A	SHANK1 ADAM22 CHRNB2 CD6 SLC4A4 PDZD2	1.95e-04	194	98	6	6833_UP
Drug	PNU-0230031 [267429-39-0]; Down 200; 1uM; PC3; HT_HG-U133A	SMURF1 SESN1 ADAM22 SBNO2 TAOK2 DMBT1	1.95e-04	194	98	6	4291_DN
Drug	Tiletamine hydrochloride; Down 200; 15.4uM; MCF7; HT_HG-U133A	ATP9B TAOK2 FBXO22 NECAP2 BTD SLC4A4	1.95e-04	194	98	6	6516_DN
Drug	Biotin [58-85-5]; Down 200; 16.4uM; PC3; HT_HG-U133A	IQSEC2 SMURF1 FBXO11 PTPN18 GRK2 GRK3	2.00e-04	195	98	6	6689_DN
Drug	Trihexyphenidyl-D,L Hydrochloride [58947-95-8]; Down 200; 11.8uM; PC3; HT_HG-U133A	PEX14 ADAM22 SH3D21 SBNO2 TAOK2 GRK3	2.00e-04	195	98	6	4015_DN
Drug	Procarbazine hydrochloride [366-70-1]; Down 200; 15.6uM; HL60; HT_HG-U133A	RCHY1 LAMC1 ADAM8 HOXA1 BTD SLC4A4	2.00e-04	195	98	6	2971_DN
Disease	triple-receptor negative breast cancer (is_marker_for)	ANTXR1 TP73	3.14e-05	3	96	2	DOID:0060081 (is_marker_for)
Disease	Reflex, Corneal, Decreased	ABAT CHRNB2	1.04e-04	5	96	2	C0151572
Disease	Reflex, Acoustic, Abnormal	ABAT CHRNB2	1.04e-04	5	96	2	C0522345
Disease	Reflex, Gag, Absent	ABAT CHRNB2	1.04e-04	5	96	2	C0234784
Disease	Reflex, Triceps, Decreased	ABAT CHRNB2	1.04e-04	5	96	2	C0751481
Disease	Reflex, Triceps, Abnormal	ABAT CHRNB2	1.04e-04	5	96	2	C0751480
Disease	Reflex, Ankle, Abnormal	ABAT CHRNB2	1.04e-04	5	96	2	C0751472
Disease	Absent reflex	ABAT CHRNB2	1.04e-04	5	96	2	C0234146
Disease	Reflex, Anal, Decreased	ABAT CHRNB2	1.04e-04	5	96	2	C0751471
Disease	Reflex, Biceps, Abnormal	ABAT CHRNB2	1.04e-04	5	96	2	C0751474
Disease	Reflex, Abnormal	ABAT CHRNB2	1.04e-04	5	96	2	C0034933
Disease	Reflex, Ankle, Decreased	ABAT CHRNB2	1.04e-04	5	96	2	C0751473
Disease	Reflex, Gag, Decreased	ABAT CHRNB2	1.04e-04	5	96	2	C0751476
Disease	Reflex, Biceps, Decreased	ABAT CHRNB2	1.04e-04	5	96	2	C0751475
Disease	Reflex, Knee, Decreased	ABAT CHRNB2	1.04e-04	5	96	2	C0751478
Disease	Reflex, Knee, Abnormal	ABAT CHRNB2	1.04e-04	5	96	2	C0751477
Disease	Palmo-Mental Reflex	ABAT CHRNB2	1.04e-04	5	96	2	C0751470
Disease	Reflex, Moro, Asymmetric	ABAT CHRNB2	1.04e-04	5	96	2	C0751479
Disease	Bulbocavernousus Reflex Absent	ABAT CHRNB2	1.04e-04	5	96	2	C0751469
Disease	Bulbocavernosus Reflex, Decreased	ABAT CHRNB2	1.04e-04	5	96	2	C0751468
Disease	Reflex, Deep Tendon, Absent	ABAT CHRNB2	1.04e-04	5	96	2	C0241772
Disease	Reflex, Corneal, Absent	ABAT CHRNB2	1.04e-04	5	96	2	C0278211
Disease	Hyperreflexia	ABAT CHRNB2	1.04e-04	5	96	2	C0151889
Disease	Abnormal Deep Tendon Reflex	ABAT CHRNB2	1.04e-04	5	96	2	C0743002
Disease	Reflex, Biceps, Absent	ABAT CHRNB2	1.04e-04	5	96	2	C0558847
Disease	Reflex, Ankle, Absent	ABAT CHRNB2	1.04e-04	5	96	2	C0558845
Disease	Reflex, Triceps, Absent	ABAT CHRNB2	1.04e-04	5	96	2	C0558846
Disease	Reflex, Anal, Absent	ABAT CHRNB2	1.04e-04	5	96	2	C0576612
Disease	Reflex, Pendular	ABAT CHRNB2	1.04e-04	5	96	2	C0277850
Disease	Hoffman's Reflex	ABAT CHRNB2	1.04e-04	5	96	2	C0277839
Disease	autism spectrum disorder (implicated_via_orthology)	SHANK1 ABCA3 LAMC1 CHRNB2 TAOK2	1.42e-04	152	96	5	DOID:0060041 (implicated_via_orthology)
Disease	Hyporeflexia	ABAT CHRNB2	1.56e-04	6	96	2	C0151888
Disease	colorectal cancer	UBAP2 LAMC1 DGKH ZAP70 SBNO2 LRP1 NANOS1 GARRE1 PDZD2	1.59e-04	604	96	9	MONDO_0005575
Disease	Autistic Disorder	SHANK1 ABAT RNF8 CHRNB2 HOXA1 BTD	2.16e-04	261	96	6	C0004352
Disease	xerostomia	ANTXR1 EGFLAM	2.90e-04	8	96	2	EFO_0009869
Disease	corpus callosum volume measurement	LAMC1 SEPSECS WNT16 EPHA3	3.25e-04	100	96	4	EFO_0010299
Disease	rheumatoid arthritis (implicated_via_orthology)	ZAP70 KMT2C	6.77e-04	12	96	2	DOID:7148 (implicated_via_orthology)
Disease	N-acetyl-isoputreanine measurement	ADAM8 PAOX	7.98e-04	13	96	2	EFO_0800107
Disease	hypertension (biomarker_via_orthology)	PTK2 GRK2 GRK3 KCNA5 SLC4A4	8.93e-04	227	96	5	DOID:10763 (biomarker_via_orthology)
Disease	Hamman-Rich syndrome	ABCA3 DPP9	9.29e-04	14	96	2	C0085786
Disease	myocardial infarction	LAMC1 AHDC1 CELSR2 HHIPL1 DMBT1 PDZD2	1.01e-03	350	96	6	EFO_0000612
Disease	lung non-small cell carcinoma (is_implicated_in)	FBXO11 PAOX KMT2C TP73	1.12e-03	139	96	4	DOID:3908 (is_implicated_in)
Disease	stomach cancer (is_marker_for)	FBXO11 SETD2 KCNA5 TP73	1.21e-03	142	96	4	DOID:10534 (is_marker_for)
Disease	joint damage measurement	SEPSECS TLCD3A TP73	1.43e-03	68	96	3	EFO_0005413
Disease	colorectal cancer, colorectal adenoma	LAMC1 MZF1 LRP1 NANOS1	1.56e-03	152	96	4	EFO_0005406, MONDO_0005575
Disease	Paroxysmal atrial fibrillation	CAND2 PTK2 KCNA5 EPHA3	1.71e-03	156	96	4	C0235480
Disease	familial atrial fibrillation	CAND2 PTK2 KCNA5 EPHA3	1.71e-03	156	96	4	C3468561
Disease	prostate cancer (is_marker_for)	PTK2 KMT2C CAMK2N1 TP73	1.71e-03	156	96	4	DOID:10283 (is_marker_for)
Disease	Persistent atrial fibrillation	CAND2 PTK2 KCNA5 EPHA3	1.71e-03	156	96	4	C2585653
Disease	Atrial Fibrillation	CAND2 PTK2 KCNA5 EPHA3	1.88e-03	160	96	4	C0004238
Disease	Idiopathic Pulmonary Fibrosis	ABCA3 DPP9	2.11e-03	21	96	2	C1800706
Disease	otitis media (implicated_via_orthology)	FBXO11 TP73	2.32e-03	22	96	2	DOID:10754 (implicated_via_orthology)
Disease	eosinophil count	UBR2 PATZ1 SMURF1 PEX14 DGKH SESN1 ZAP70 SBNO2 SETD2 SEPSECS ANTXR1 PLOD1	3.21e-03	1488	96	12	EFO_0004842
Disease	diabetes mellitus (implicated_via_orthology)	PTPRN LRP1	3.24e-03	26	96	2	DOID:9351 (implicated_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
EARGGREGAVLAGEF	PTPN18	16	Q99952
IIGRGGFGEVYGCRK	GRK3	196	P35626
VEFRFDCGSGTGVLR	EGFLAM	671	Q63HQ2
TGGLREEQRYGLSCG	ELL2	6	O00472
GVCSRTRGVGVNEYG	ADAM23	406	O75077
LVLICAGQGGRREDG	ANTXR1	21	Q9H6X2
LFVAVGQVGGACRDV	DDX4	501	Q9NQI0
IQCLGRGGFGVVFEA	EIF2AK3	596	Q9NZJ5
DGVQGICFGGRCKTR	ADAM22	536	Q9P0K1
RASVEGGGFNERCLV	ABCA3	1011	Q99758
EGSGQVFLGGRNRVC	AASDH	396	Q4L235
EFQGELTELGCRRGG	ARHGEF15	636	O94989
AGGVARGFRGCLQGV	CELSR2	1751	Q9HCU4
RAFGVGERDPCDFIG	AHDC1	1331	Q5TGY3
VGGPVCGNLFVERGE	ADAM8	406	P78325
SRSCGGGVQERGVFC	ADAMTS12	1436	P58397
IIGRGGFGEVYGCRK	GRK2	196	P25098
RVFFGEGDGIIRELC	AOX1	446	Q06278
LGVGRGNCEEKRGVN	MTUS2	371	Q5JR59
LRRNRQGDVGGTCGV	ADAMTS1	186	Q9UHI8
TRDLDFGGNGEVRCN	PCDHGB6	371	Q9Y5F9
GGEEGLLFGNRVGER	AOC2	496	O75106
LRLVDGGGACAGRVE	CD6	161	P30203
GFFGNGEIGCDRIVT	FBXO22	356	Q8NEZ5
DGLFGQCQVGVGQAR	PTPRN	56	Q16849
VVCGSFGQGAEGRLL	KMT2C	961	Q8NEZ4
IGAGEFGEVCRGRLK	EPHB4	621	P54760
GRGRLFCGDVGQNKF	HHIPL1	411	Q96JK4
GVGEFRCRDGTCIGN	LRP1	2606	Q07954
GRRTCAIGDGGNDVS	ATP9B	866	O43861
AGGRRLGKCEAAGEN	IQSEC2	676	Q5JU85
GVVLGGCGDKSIRFR	ABAT	461	P80404
GEIFGIDLRCGNQGS	DCAF4L2	246	Q8NA75
GTRKGQGGECEIRRA	KIFC1	476	Q9BW19
EERIEASAGVGGGLC	FBXO31	41	Q5XUX0
AVDGEPRFGCARGGN	NANOS1	56	Q8WY41
CGVGVAFNARIGGVR	PCSK4	216	Q6UW60
VGACDLQGELDRFGG	NUDT6	41	P53370
QQRGFEIVGSCGGGV	KCTD1	211	Q719H9
IAGGRDCIRGQMGIF	PDZD2	601	O15018
GSRVFSICRGEGEGQ	NES	486	P48681
SCGGDDRFLVGRGVQ	HOXA1	46	P49639
GEVGEGRIFAGQNRL	PRSS54	361	Q6PEW0
DNFRILVCGGDGSVG	DGKH	381	Q86XP1
GSEFLRLQVEGGGCS	ISCA2	66	Q86U28
EVKYVSRCGAGGARG	ECEL1	16	O95672
IALNRVGVDYEGGGC	PLOD1	666	Q02809
NGGRFCDVLLRVGDE	PATZ1	36	Q9HBE1
DGQVLGRRSFEGRIC	TP73	281	O15350
EFGGFRIGNGEVRGR	C17orf99	246	Q6UX52
LIRGRGDGDEVGVRC	GRM6	116	O15303
VRGGDEARAGCGQAT	KCNA5	16	P22460
RDGGICIFNGGRGLL	FBXO11	731	Q86XK2
VIDGRGSCQRGLRFE	DPP9	676	Q86TI2
CGVGVAYNARIGGVR	FURIN	211	P09958
EEAFFRGVSQGRGGL	FURIN	271	P09958
RGGGARVCEVAADEG	CACNA1I	1011	Q9P0X4
RERGCDGCLAGIEVQ	GARRE1	241	O15063
VRCGGLGFDTCGQEI	BTD	461	P43251
VVGAGEFGEVCSGRL	EPHA3	626	P29320
RGFIRTGGDEQQALC	LAMC1	191	P11047
GRGRIFCGDVGQNRF	HHIPL2	436	Q6UWX4
LVNGGGRCAGRVEIY	CD163	721	Q86VB7
LFQRCEGAEEGTRGV	CAND2	941	O75155
GGDRCQGRVEVLYRG	DMBT1	1256	Q9UGM3
QTGDRICDGVQFGAG	SAMM50	451	Q9Y512
ILGAGCDRFGRRAVF	SLC22A31	146	A6NKX4
GGRIRSERCFGGVVE	PAOX	51	Q6QHF9
VIGAGEFGEVCSGRL	EPHA6	636	Q9UF33
MFEELRNACRGGGVG	RTCB	46	Q9Y3I0
CGGGRDQDEELGIRI	SESN1	26	Q9Y6P5
EGECQGRRGVFPDNF	SH3D21	106	A4FU49
LLEDGCEVTVGRGFG	RNF8	31	O76064
LQQEERAGGCRGVRA	NTN5	466	Q8WTR8
RIELGRCIGEGQFGD	PTK2	421	Q05397
AFRALQGCGAVGDRG	TAOK2	1096	Q9UL54
GIGGRESRNGCLDVE	SBNO2	946	Q9Y2G9
DCLGVQREDRRGGDG	PEX14	341	O75381
GGSVVDCRGLLENEG	SMURF1	146	Q9HCE7
QFGAALVGAARREGG	SHANK1	1231	Q9Y566
GCGLREAVDGVRFIA	CHRNB2	421	P17787
CHGGRVGFFQGDIRL	ACSL6	336	Q9UKU0
GDGGDVGQIFSCRLQ	CAMK2N1	16	Q7Z7J9
RGEFCSQGVREGLIV	VPS51	481	Q9UID3
DIELGCGNFGSVRQG	ZAP70	341	P43403
GGNRGREFRGEENGI	UBAP2	141	Q5T6F2
QRLRGDLGDFFVGCI	TLCD3A	136	Q8TBR7
GRGAQYIRAAGTCGV	MRPL2	201	Q5T653
REGARLGIQECGSQF	WNT16	71	Q9UBV4
GSANCRGYLGGENRV	SETD2	1681	Q9BYW2
RRQRGAGAGEGEFVC	ZNF74	236	Q16587
GDCEELQRTGRFCGG	SLC4A4	431	Q9Y6R1
FLGNCGVGEREGRVA	SEPSECS	66	Q9HD40
REDGASGQERGQRGC	RCHY1	6	Q96PM5
GERQASVCRDFGVPG	TIGD5	71	Q53EQ6
CGSGVGIFLRVRECQ	UBR2	1666	Q8IWV8
FRLCVGQGDTRGDGS	TARM1	11	B6A8C7
GVVRGGRCDVCGKVF	MZF1	351	P28698
EDGNGRRAFIGIGFG	NECAP2	96	Q9NVZ3