Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainTNF_1

TNFSF10 EDA

1.21e-0317572PS00251
DomainTNF

TNFSF10 EDA

1.36e-0318572SM00207
DomainTNF

TNFSF10 EDA

1.51e-0319572PF00229
DomainTNF_dom

TNFSF10 EDA

1.51e-0319572IPR006052
DomainTNF_2

TNFSF10 EDA

1.51e-0319572PS50049
Domain-

TNFSF10 EDA

1.02e-02505722.60.120.40
Pubmed

Effects of the jimpy mutation on mouse retinal structure and function.

EDA PLP1

2.73e-06258226011242
Pubmed

Differential expression of apoptotic markers in jimpy and in Plp overexpressors: evidence for different apoptotic pathways.

EDA PLP1

2.73e-06258212165674
Pubmed

An X-linked recessive mutation producing cleft palate, crooked tail, and polydactyly in mice.

EDA PLP1

2.73e-0625822230077
Pubmed

DYRK gene structure and erythroid-restricted features of DYRK3 gene expression.

DYRK4 DYRK3

2.73e-06258215607427
Pubmed

Amino acid sensor GCN2 promotes SARS-CoV-2 receptor ACE2 expression in response to amino acid deprivation.

ACE2 EIF2AK4

2.73e-06258235778545
Pubmed

X-linked polydactyly (Xpl), a new mutation in the mouse.

EDA PLP1

2.73e-0625827391545
Pubmed

Differences in levels of neuroglial cell death in jimpy male mice and carrier females.

EDA PLP1

2.73e-0625822364893
Pubmed

Jimpy 4J: a new X-linked mouse mutation producing severe CNS hypomyelination.

EDA PLP1

2.73e-0625828829919
Pubmed

Jimpy mutation affects astrocytes: lengthening of the cell cycle in vitro.

EDA PLP1

2.73e-0625828269866
Pubmed

Radial component of CNS myelin: junctional subunit structure and supramolecular assembly.

EDA PLP1

8.19e-0635822113569
Pubmed

Neurosteroid progesterone is up-regulated in the brain of jimpy and shiverer mice.

EDA PLP1

8.19e-06358210594919
Pubmed

New insights on neuronal alterations in jimpy mutant brain.

EDA PLP1

8.19e-06358215139292
Pubmed

Abnormal Pain Sensation in Mice Lacking the Prokineticin Receptor PKR2: Interaction of PKR2 with Transient Receptor Potential TRPV1 and TRPA1.

TRPV1 PROKR2

1.64e-05458231883821
Pubmed

Cell-specific loss of kappa-opioid receptors in oligodendrocytes of the dysmyelinating jimpy mouse.

EDA PLP1

1.64e-05458219110031
Pubmed

Apcdd1 stimulates oligodendrocyte differentiation after white matter injury.

APCDD1 PLP1

1.64e-05458225946682
Pubmed

Location of phosphorylase kinase (Phk) in the mouse X chromosome.

EDA PLP1

2.72e-0555824726088
Pubmed

eIF2α phosphorylation controls thermal nociception.

TRPV1 EIF2AK4

4.08e-05658227698114
Pubmed

Sequence characteristics, subcellular localization, and substrate specificity of DYRK-related kinases, a novel family of dual specificity protein kinases.

DYRK4 DYRK3

5.71e-0575829748265
Pubmed

An Interaction Landscape of Ubiquitin Signaling.

GTF2E1 ERCC5 DERL1 LRP2 HACD1 YARS2

1.49e-0448158628190767
Pubmed

Conservation and reorganization of loci on the mammalian X chromosome: a molecular framework for the identification of homologous subchromosomal regions in man and mouse.

EDA PLP1

1.78e-04125822899541
Pubmed

Localization of murine X and autosomal sequences homologous to the human Y located testis-determining region.

EDA PLP1

2.11e-04135822721933
Pubmed

Systematic identification of pathological lamin A interactors.

ADGRG7 DERL1 CMTM5 PLP1 HACD1

2.49e-0433758524623722
Pubmed

Targeted in situ cross-linking mass spectrometry and integrative modeling reveal the architectures of three proteins from SARS-CoV-2.

ACE2 EIF3E

2.83e-041558234373319
Pubmed

Comparative genomic analysis of eutherian tumor necrosis factor ligand genes.

TNFSF10 EDA

4.11e-041858226646413
Pubmed

Rapid identification of 14-3-3-binding proteins by protein microarray analysis.

SMAGP FGF12

5.62e-042158216260042
Pubmed

Defining the membrane proteome of NK cells.

NPC1 ATP11B DERL1 EIF3E ABCD1 ARPC3 RHOT1 STT3B

6.83e-04116858819946888
Pubmed

An introduction to TRP channels.

TRPV1 PKD2L2

9.34e-042758216460286
Pubmed

Genetic link between renal birth defects and congenital heart disease.

TBC1D32 LRP2

1.00e-032858227002738
Pubmed

Specification of dopaminergic subsets involves interplay of En1 and Pitx3.

APCDD1 SMPDL3A

1.23e-033158223863478
Pubmed

Onset of Spinal Cord Astrocyte Precursor Emigration from the Ventricular Zone Involves the Zeb1 Transcription Factor.

APCDD1 PLP1

1.31e-033258227806288
Pubmed

Lhx2 is a direct NF-κB target gene that promotes primary hair follicle placode down-growth.

PROKR2 EDA

1.40e-033358226952977
Pubmed

A quantitative analysis of the spatiotemporal pattern of transient receptor potential gene expression in the developing mouse cochlea.

TRPV1 PKD2L2

1.40e-033358219834762
Pubmed

C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.

NPC1 VPS13D LRP2 PLXNA1 STT3B

1.53e-0350458534432599
Cytoband6q22.31

TBC1D32 SMPDL3A

5.40e-04275826q22.31
Cytoband3q28

P3H2 FGF12

6.67e-04305823q28
Cytoband3q13.2

SLC9C1 ATG3

7.12e-04315823q13.2
CytobandEnsembl 112 genes in cytogenetic band chr3q13

GTF2E1 SLC9C1 ATG3

2.79e-03221583chr3q13
GeneFamilyCD molecules|Endogenous ligands|Tumor necrosis factor superfamily|Death inducing signaling complex

TNFSF10 EDA

5.46e-0418352781
GeneFamilyTransient receptor potential cation channels

TRPV1 PKD2L2

1.33e-0328352249
GeneFamilyProteases, serine

TMPRSS11E PRSS21

6.60e-0363352738
GeneFamilyBasic leucine zipper proteins|BTB domain containing

ZBTB49 RCBTB1

2.77e-02134352861
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

APCDD1 MYO10 LRP2 CMTM5 PLP1

4.75e-0618958542ab4cc5fbf8580841f31889446fe4499df1a464
ToppCellParenchymal-NucSeq-Epithelial-Epi_alveolar-AT2|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

NPC1 GANC P3H2 SGPP2 LRP2

5.95e-061985852e2a4e1756bba6f4fbe529559a97d2993c890b4b
ToppCellcontrol-B_cell|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SLC9C1 MYO10 PKDCC CMTM5

5.23e-051575841269b55f2ef6a493f6116b131cc5cc7b8897d63e
ToppCellFrontal_cortex-Macroglia|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

ATG3 CMTM5 PLP1 HACD1

7.62e-05173584ac70145e093ef0df43811e7c67a865ccdd45a5e3
ToppCellE16.5-Epithelial-Epithelial_Airway-Neurosecretory|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ACE2 FGF12 ST8SIA5 PLXNA1

7.96e-0517558438dec78efc99fe23479cba68cfa441e62bd6a08b
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_6|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SMAGP PKD2L2 MYO10 P3H2

8.32e-05177584c9e5820ff0bc7ad1adcfb2651713fdfc58bced56
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_6|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SMAGP PKD2L2 MYO10 P3H2

8.32e-051775843a150dcaefa342d49968b42c7cdb1fbb633adcd0
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_MOBP_COL18A1|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TMPRSS11E LRP2 CMTM5 PLP1

8.32e-0517758480aee5154f21810be0645d003b06568d4dcecc36
ToppCellPCW_05-06-Neuronal-Neuronal_SCP-neuro_pre_proliferating_SCP_(4)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

LRP2 CMTM5 ST8SIA5 PLP1

8.32e-0517758459726bfd98f656fdcedf448a7e2e76a9bfad8285
ToppCellGlobus_pallidus-Macroglia|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

NPC1 CMTM5 PLP1 HACD1

8.69e-05179584ab50f711b004b96107f813c9a2526ec21d1c8027
ToppCelldroplet-Bladder-nan-24m-Epithelial-nan|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CMTM5 EDA PLP1 DYRK3

8.69e-05179584dfd9d29281510d32f1a2e8336d2e58ef496cfd1d
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

APCDD1 LRP2 CMTM5 PLP1

9.87e-05185584b5277190866d9eb5b85eceaa5ba116ea6e6f286b
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

APCDD1 LRP2 CMTM5 PLP1

1.03e-0418758497e520705491c8f52a32025311a9fa7b9176979a
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

APCDD1 MYO10 CMTM5 PLP1

1.05e-04188584505b6b4277d7dea87aee27191d0acca67928b8e6
ToppCellNon-neuronal-Non-dividing-OPC|World / Primary Cells by Cluster

APCDD1 MYO10 CMTM5 PLP1

1.07e-0418958413848a031ab896b4b24c8319e4745b9b17ff9cfd
ToppCellNon-neuronal-Non-dividing-OPC-OPC|World / Primary Cells by Cluster

APCDD1 MYO10 CMTM5 PLP1

1.07e-04189584ddf5be73912570c32c50f4ac2902da9b590526f8
ToppCellrenal_cortex_nuclei-Adult_normal_reference|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

LENG8 ADGRG7 MYO10 P3H2

1.07e-04189584a48df46274d51e84ffb40264646de7346104efb9
ToppCellNon-neuronal-Non-dividing-OPC-OPC-30|World / Primary Cells by Cluster

APCDD1 MYO10 CMTM5 PLP1

1.07e-04189584313d165fad541ec6e8dd524b88856e2c93eeb681
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

APCDD1 LRP2 CMTM5 PLP1

1.09e-0419058407f21386ea6eb23416a537d2250e3042efe93fb0
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

APCDD1 MYO10 CMTM5 PLP1

1.09e-041905842de8e4cfeee350a9a76af749d6ce58d948c129b8
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

APCDD1 LRP2 CMTM5 PLP1

1.09e-04190584ae97df1b06bcd46c05759b53c35dc8fea97f4ac1
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

APCDD1 LRP2 CMTM5 PLP1

1.12e-041915842b056cbe2e82e056e1f798974999378460eb1d16
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

APCDD1 MYO10 CMTM5 PLP1

1.12e-04191584f3158cedf67e3b90aa94ea1f61c72c33aaa2d5ba
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

APCDD1 MYO10 CMTM5 PLP1

1.12e-04191584a90c8ab2077e52bbc998457c85a1b9867f9c8c93
ToppCelldroplet-Heart-nan-18m-Endothelial-endocardial_endothelial_cells|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PROKR2 TNFSF10 PKDCC RALGAPA2

1.14e-041925840b9b2eaed45456d7d74ce78a64ef4a26ac2458fb
ToppCell5'-GW_trimst-1.5-SmallIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SMAGP TNFSF10 LRRC70 RALGAPA2

1.14e-041925844e63d95f75fe6eb3f817e84528883e95093c5bbd
ToppCell5'-GW_trimst-1.5-SmallIntestine-Endothelial-lymphatic_endothelial|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SMAGP TNFSF10 LRRC70 RALGAPA2

1.14e-04192584fa0ef05a32c661bdd59b5a9b6f75fd647ee937f3
ToppCelldroplet-Heart-4Chambers-21m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SMAGP PROKR2 TNFSF10 RALGAPA2

1.21e-04195584df644b4c3ddccd34614ece5a2378000e6bc0fa10
ToppCelldroplet-Heart-nan-18m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PROKR2 TNFSF10 PKDCC RALGAPA2

1.23e-04196584e386526332138e636aef2542c11316347a45689c
ToppCellBronchial-NucSeq-Epithelial-Epi_alveolar-AT2|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

GANC P3H2 SGPP2 LRP2

1.28e-04198584f948391296c261c473d339069a6d0f20ccd6f38f
ToppCellBronchial-NucSeq-Epithelial-Epi_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SLC9C1 GANC P3H2 LRP2

1.31e-04199584725610310e5c5fd7120c0be9acb55bf152026ddd
ToppCellMacroglial|World / cells hierarchy compared to all cells using T-Statistic

APCDD1 MYO10 CMTM5 PLP1

1.33e-04200584e6935ad49216d2500c15c05cbc2b89402c65e838
ToppCellBrain_organoid-organoid_Tanaka_cellReport-10w-Macroglial-Astrocyte|10w / Sample Type, Dataset, Time_group, and Cell type.

APCDD1 MYO10 LRP2 PLP1

1.33e-0420058475f5ea38fbd341b80a8058077a04447f0e0eea28
DrugVAL-TRP

ACE2 GANC STT3B

5.45e-077583CID000168182
Drugdibenzo-30-crown-10

EDA PLP1

6.38e-062582CID000087120
Drugdicyclohexano-24-crown-8

EDA PLP1

6.38e-062582CID000087119
Drug4'-nitrobenzo-15-crown-5

EDA PLP1

6.38e-062582CID000143747
Diseasefacial morphology measurement

CFAP251 P3H2 SGPP2 EIF3E PKDCC EDA RHOT1

2.79e-05466567EFO_0007841
DiseaseHypoxanthine measurement

ERCC5 EDA

2.72e-0413562EFO_0021604

Protein segments in the cluster

PeptideGeneStartEntry
KVSVLFLYSYRDDYY

EIF2AK4

1631

Q9P2K8
TFYYLGQELQYIYFI

TBC1D32

416

Q96NH3
YKLIYRHYATLYFVF

AP3S2

61

P59780
YNQKEFQLYSYACVY

ADGRG7

371

Q96K78
LFSVFYQYLEQSKYR

DCUN1D5

176

Q9BTE7
QTRTYDLYITYDKYY

ATG3

196

Q9NT62
KFYRELEDYFYYSQL

CFAP251

951

Q8TBY9
FSYPVYRAFLQYLYT

RCBTB1

416

Q8NDN9
QYDGIFYEFRSYYLK

NIPSNAP3A

31

Q9UFN0
YKYLNKAAEFYINYV

INTS10

196

Q9NVR2
YRLYFSQQTYYRVSN

ABCD1

171

P33897
SYYVIYFELETFYQQ

ANKAR

436

Q7Z5J8
TILDSKQFIKYYNYF

SMPDL3A

396

Q92484
KQFIKYYNYFFVSYD

SMPDL3A

401

Q92484
EFTAYRILYYIFTKN

LENG8

661

Q96PV6
YQFKRLKYYYAVVDC

ESF1

426

Q9H501
YVYSFRSEQFVYYLT

PLXNA1

246

Q9UIW2
YYAINTVYVYGQEKY

RHOT1

456

Q8IXI2
YRLYNLDVYGYQIYD

GANC

246

Q8TET4
LYLVNLYFLYQYSTR

DERL1

71

Q9BUN8
YNLFQRYKRNQIYTY

MYO10

81

Q9HD67
RYYLRNLTIDGYFYS

LRP2

3206

P98164
YLQFAYYRVGEYVKA

P3H2

311

Q8IVL5
YSQIYFIFYENFIAL

RALGAPA2

51

Q2PPJ7
RLEYYSFYQSARYNV

LRRC70

566

Q7Z2Q7
YSVFYVFYEQYLTII

NPC1

1081

O15118
YEHQKVYTYIQSRFY

DYRK4

256

Q9NR20
YFIYSQVEVYYINFT

EDA

301

Q92838
IYYFKANVFFKNYEI

ARPC3

46

O15145
IRLPNKYNVSFDYYY

HACD1

236

B0YJ81
KYNVSFDYYYFLLIT

HACD1

241

B0YJ81
SFIRYYTRTLYQFQF

ACE2

511

Q9BYF1
RFYHNNTFKAYQFYY

APCDD1

96

Q8J025
EYLDTLYRYAKFQYE

EIF3E

126

P60228
YSEYLYQEQYFIKKD

CGRRF1

131

Q99675
FEYQKLYTYIQSRFY

DYRK3

361

O43781
VFENYYVIYSSTLYR

FGF12

151

P61328
YYFINYRTLVNVVKY

GTF2E1

91

P29083
EKRNLYNAYRFFFTY

PKDCC

336

Q504Y2
YIEFVDIYYSLNIYL

SLC9C1

321

Q4G0N8
FFYLYKNKGSYVTYE

SMAGP

56

Q0VAQ4
YYNVIICYTLFYLFA

SLC6A5

286

Q9Y345
YQVLQAYDFYYLFQR

YARS2

221

Q9Y2Z4
VYRNFFNKNKFVEYY

ERCC5

821

P28715
LYGRNYIKRYFEFYE

ST8SIA5

36

O15466
VQKYVVKNYFYYYLF

SGPP2

76

Q8IWX5
VKNYFYYYLFQFSAA

SGPP2

81

Q8IWX5
LAFLFLYATQYYQRF

CMTM5

71

Q96DZ9
YYIRIATLVQYFFYK

ATP11B

871

Q9Y2G3
HYVRYNQKKTYNYYS

TMPRSS11E

41

Q9UL52
VKRIFYFNFLVYCLY

TRPV1

431

Q8NER1
YSKRVYIAYSTFYIV

STT3B

286

Q8TCJ2
RYFVLRAQQLYYYKD

ARHGAP25

66

P42331
QQLYYKSYFLFIFGV

PROKR2

216

Q8NFJ6
FYSVKLLRYVSYYDY

PKD2L2

266

Q9NZM6
IFQYDKYVNVFYKFS

ZNF430

176

Q9H8G1
SLQAYYTRYFVSNIY

PRSS21

111

Q9Y6M0
NYYYKLRNFYSKQYH

ZBTB49

211

Q6ZSB9
FYYIYSQTYFRFQEE

TNFSF10

181

P50591
QLYYENFIYIAATYT

VPS13D

3586

Q5THJ4
LIETYFSKNYQDYEY

PLP1

46

P60201