Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	arachidonate 8(R)-lipoxygenase activity	ALOX12B ALOX15B	5.66e-06	2	48	2	GO:0047677
GeneOntologyMolecularFunction	linoleate 9S-lipoxygenase activity	ALOX12B ALOX15B	5.66e-06	2	48	2	GO:1990136
GeneOntologyMolecularFunction	snRNA binding	MEPCE RBMXL2 RBMXL3	3.48e-04	57	48	3	GO:0017069
GeneOntologyBiologicalProcess	regulation of mRNA splicing, via spliceosome	RBM15B RBM5 TRA2A RBMXL2 SRSF2 RBMXL3 TRA2B	1.89e-08	129	48	7	GO:0048024
GeneOntologyBiologicalProcess	regulation of RNA splicing	RBM15B RBM5 TRA2A RBMXL2 SRSF1 SRSF2 RBMXL3 TRA2B	2.40e-08	207	48	8	GO:0043484
GeneOntologyBiologicalProcess	regulation of mRNA processing	RBM15B RBM5 TRA2A RBMXL2 SRSF2 RBMXL3 TRA2B	7.66e-08	158	48	7	GO:0050684
GeneOntologyBiologicalProcess	mRNA splicing, via spliceosome	RBM15B RBM5 TRA2A RSRP1 RBMXL2 SRSF1 SRSF2 RBMXL3 TRA2B	1.19e-07	358	48	9	GO:0000398
GeneOntologyBiologicalProcess	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile	RBM15B RBM5 TRA2A RSRP1 RBMXL2 SRSF1 SRSF2 RBMXL3 TRA2B	1.19e-07	358	48	9	GO:0000377
GeneOntologyBiologicalProcess	RNA splicing, via transesterification reactions	RBM15B RBM5 TRA2A RSRP1 RBMXL2 SRSF1 SRSF2 RBMXL3 TRA2B	1.31e-07	362	48	9	GO:0000375
GeneOntologyBiologicalProcess	positive regulation of RNA splicing	TRA2A RBMXL2 SRSF1 RBMXL3 TRA2B	3.50e-07	63	48	5	GO:0033120
GeneOntologyBiologicalProcess	mRNA processing	RBM15B RBM5 CPSF1 TRA2A RSRP1 RBMXL2 SRSF1 SRSF2 RBMXL3 TRA2B	4.48e-07	551	48	10	GO:0006397
GeneOntologyBiologicalProcess	alternative mRNA splicing, via spliceosome	RBM15B RBM5 SRSF1 SRSF2 TRA2B	1.09e-06	79	48	5	GO:0000380
GeneOntologyBiologicalProcess	RNA splicing	RBM15B RBM5 TRA2A RSRP1 RBMXL2 SRSF1 SRSF2 RBMXL3 TRA2B	2.01e-06	502	48	9	GO:0008380
GeneOntologyBiologicalProcess	positive regulation of mRNA splicing, via spliceosome	TRA2A RBMXL2 RBMXL3 TRA2B	3.27e-06	44	48	4	GO:0048026
GeneOntologyBiologicalProcess	positive regulation of mRNA processing	TRA2A RBMXL2 RBMXL3 TRA2B	5.06e-06	49	48	4	GO:0050685
GeneOntologyBiologicalProcess	regulation of mRNA metabolic process	RBM15B RBM5 TRA2A RBMXL2 SRSF1 SRSF2 RBMXL3 TRA2B	7.55e-06	443	48	8	GO:1903311
GeneOntologyBiologicalProcess	regulation of alternative mRNA splicing, via spliceosome	RBM15B RBM5 SRSF2 TRA2B	1.07e-05	59	48	4	GO:0000381
GeneOntologyBiologicalProcess	mRNA metabolic process	RBM15B RBM5 CPSF1 TRA2A RSRP1 RBMXL2 SRSF1 SRSF2 RBMXL3 TRA2B	4.03e-05	917	48	10	GO:0016071
GeneOntologyBiologicalProcess	negative regulation of wound healing, spreading of epidermal cells	CLASP1 FIGNL2	5.28e-05	5	48	2	GO:1903690
GeneOntologyBiologicalProcess	hepoxilin metabolic process	ALOX12B ALOX15B	1.47e-04	8	48	2	GO:0051121
GeneOntologyBiologicalProcess	hepoxilin biosynthetic process	ALOX12B ALOX15B	1.47e-04	8	48	2	GO:0051122
GeneOntologyBiologicalProcess	positive regulation of extracellular matrix disassembly	CLASP1 DDR2	2.36e-04	10	48	2	GO:0090091
GeneOntologyBiologicalProcess	regulation of wound healing, spreading of epidermal cells	CLASP1 FIGNL2	2.88e-04	11	48	2	GO:1903689
GeneOntologyBiologicalProcess	lipoxygenase pathway	ALOX12B ALOX15B	2.88e-04	11	48	2	GO:0019372
GeneOntologyBiologicalProcess	negative regulation of axon regeneration	PTPRS FIGNL2	7.05e-04	17	48	2	GO:0048681
GeneOntologyCellularComponent	spliceosomal complex	RBM5 TRA2A RBMXL2 SRSF1 SRSF2 RBMXL3 TRA2B	4.90e-07	215	47	7	GO:0005681
Domain	RRM_1	RBM15B RBM5 TRA2A RBMXL2 SRSF1 SRSF2 RBMXL3 TRA2B EIF4B	1.39e-09	208	45	9	PF00076
Domain	RRM	RBM15B RBM5 TRA2A RBMXL2 SRSF1 SRSF2 RBMXL3 TRA2B EIF4B	2.02e-09	217	45	9	SM00360
Domain	RRM_dom	RBM15B RBM5 TRA2A RBMXL2 SRSF1 SRSF2 RBMXL3 TRA2B EIF4B	2.99e-09	227	45	9	IPR000504
Domain	RRM	RBM15B RBM5 TRA2A RBMXL2 SRSF1 SRSF2 RBMXL3 TRA2B EIF4B	3.36e-09	230	45	9	PS50102
Domain	-	RBM15B RBM5 TRA2A RBMXL2 SRSF1 SRSF2 RBMXL3 TRA2B EIF4B	5.63e-09	244	45	9	3.30.70.330
Domain	Nucleotide-bd_a/b_plait	RBM15B RBM5 TRA2A RBMXL2 SRSF1 SRSF2 RBMXL3 TRA2B EIF4B	9.15e-09	258	45	9	IPR012677
Domain	ZF_CCHC_HIVEP	HIVEP3 HIVEP1	5.68e-06	2	45	2	PS51811
Domain	LIPOXYGENASE_2	ALOX12B ALOX15B	8.46e-05	6	45	2	PS00081
Domain	LipOase	ALOX12B ALOX15B	8.46e-05	6	45	2	IPR000907
Domain	LipOase_Fe_BS	ALOX12B ALOX15B	8.46e-05	6	45	2	IPR020833
Domain	LipOase_CS	ALOX12B ALOX15B	8.46e-05	6	45	2	IPR020834
Domain	LipOase_mml	ALOX12B ALOX15B	8.46e-05	6	45	2	IPR001885
Domain	LIPOXYGENASE_1	ALOX12B ALOX15B	8.46e-05	6	45	2	PS00711
Domain	LipOase_C	ALOX12B ALOX15B	8.46e-05	6	45	2	IPR013819
Domain	Lipoxygenase	ALOX12B ALOX15B	8.46e-05	6	45	2	PF00305
Domain	LIPOXYGENASE_3	ALOX12B ALOX15B	8.46e-05	6	45	2	PS51393
Domain	Tyr_kinase_rcpt_2_CS	LTK DDR2	3.08e-04	11	45	2	IPR002011
Domain	RECEPTOR_TYR_KIN_II	LTK DDR2	3.69e-04	12	45	2	PS00239
Domain	Crystall	CRYBA2 CRYBB3	5.84e-04	15	45	2	PF00030
Domain	CRYSTALLIN_BETA_GAMMA	CRYBA2 CRYBB3	5.84e-04	15	45	2	PS50915
Domain	Beta/gamma_crystallin	CRYBA2 CRYBB3	5.84e-04	15	45	2	IPR001064
Domain	XTALbg	CRYBA2 CRYBB3	5.84e-04	15	45	2	SM00247
Domain	G_crystallin-rel	CRYBA2 CRYBB3	8.47e-04	18	45	2	IPR011024
Domain	LH2	ALOX12B ALOX15B	8.47e-04	18	45	2	SM00308
Domain	PLAT	ALOX12B ALOX15B	1.16e-03	21	45	2	PF01477
Domain	PLAT	ALOX12B ALOX15B	1.16e-03	21	45	2	PS50095
Domain	PLAT/LH2_dom	ALOX12B ALOX15B	1.16e-03	21	45	2	IPR001024
Domain	-	ALOX12B ALOX15B	1.16e-03	21	45	2	2.60.60.20
Domain	RRM_dom_euk	RBMXL2 SRSF2	1.39e-03	23	45	2	IPR003954
Domain	RRM_1	RBMXL2 SRSF2	1.39e-03	23	45	2	SM00361
Domain	Keratin_I	KRT20 KRT17	5.04e-03	44	45	2	IPR002957
Domain	Intermediate_filament_CS	KRT20 KRT17	1.01e-02	63	45	2	IPR018039
Domain	Filament	KRT20 KRT17	1.27e-02	71	45	2	SM01391
Pathway	WP_MRNA_PROCESSING	RBM15B RBM5 CPSF1 OAS1 RBMXL2 SRSF1 SRSF2 RBMXL3 TRA2B	4.57e-06	451	41	9	MM15946
Pathway	WP_MRNA_PROCESSING	RBM5 CPSF1 SRSF1 SRSF2 TRA2B	3.05e-05	126	41	5	M39406
Pubmed	A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain.	RBM15B RBM5 CPSF1 TRA2A RBMXL2 SRSF1 SRSF2 RBMXL3 TRA2B	1.05e-09	347	48	9	16033648
Pubmed	Cloning of a gene, YT521, for a novel RNA splicing-related protein induced by hypoxia/reoxygenation.	SRSF1 SRSF2 TRA2B	9.86e-09	4	48	3	9473574
Pubmed	Angulin proteins ILDR1 and ILDR2 regulate alternative pre-mRNA splicing through binding to splicing factors TRA2A, TRA2B, or SRSF1.	TRA2A SRSF1 TRA2B	2.46e-08	5	48	3	28785060
Pubmed	HIV-1 transcription is regulated by splicing factor SRSF1.	SRSF1 SRSF2 TRA2B	4.92e-08	6	48	3	25416801
Pubmed	Up-regulation of the ubiquitous alternative splicing factor Tra2beta causes inclusion of a germ cell-specific exon.	SRSF1 TRA2B CLASP1	4.04e-07	11	48	3	16000324
Pubmed	Associations of folate, vitamin B12, homocysteine, and folate-pathway polymorphisms with prostate-specific antigen velocity in men with localized prostate cancer.	FUT2 CUBN FOLH1	5.38e-07	12	48	3	20852008
Pubmed	Genome-wide analysis reveals SR protein cooperation and competition in regulated splicing.	SRSF1 SRSF2	1.87e-06	2	48	2	23562324
Pubmed	Alterations in expression pattern of splicing factors in epithelial ovarian cancer and its clinical impact.	SRSF1 TRA2B	1.87e-06	2	48	2	23748175
Pubmed	Sequence determinants for the reaction specificity of murine (12R)-lipoxygenase: targeted substrate modification and site-directed mutagenesis.	ALOX12B ALOX15B	1.87e-06	2	48	2	16129665
Pubmed	Protein-protein interactions and 5'-splice-site recognition in mammalian mRNA precursors.	SRSF1 SRSF2	1.87e-06	2	48	2	8139654
Pubmed	SRSF1 regulates the assembly of pre-mRNA processing factors in nuclear speckles.	SRSF1 SRSF2	1.87e-06	2	48	2	22855529
Pubmed	Uncoupling of growth plate maturation and bone formation in mice lacking both Schnurri-2 and Schnurri-3.	HIVEP3 HIVEP2	1.87e-06	2	48	2	20404140
Pubmed	The human splicing factors ASF/SF2 and SC35 possess distinct, functionally significant RNA binding specificities.	SRSF1 SRSF2	1.87e-06	2	48	2	7543047
Pubmed	Growth hormone deficiency and splicing fidelity: two serine/arginine-rich proteins, ASF/SF2 and SC35, act antagonistically.	SRSF1 SRSF2	1.87e-06	2	48	2	18586677
Pubmed	Haploinsufficiency of the germ cell-specific nuclear RNA binding protein hnRNP G-T prevents functional spermatogenesis in the mouse.	RBMXL2 RBMXL3	1.87e-06	2	48	2	18562473
Pubmed	An ancient germ cell-specific RNA-binding protein protects the germline from cryptic splice site poisoning.	RBMXL2 RBMXL3	1.87e-06	2	48	2	30674417
Pubmed	Expression levels of hnRNP G and hTra2-beta1 correlate with opposite outcomes in endometrial cancer biology.	RBMXL2 TRA2B	1.87e-06	2	48	2	20607830
Pubmed	Human Tra2 proteins are sequence-specific activators of pre-mRNA splicing.	TRA2A TRA2B	1.87e-06	2	48	2	9546399
Pubmed	Differential Effects of Tra2ß Isoforms on HIV-1 RNA Processing and Expression.	TRA2A TRA2B	1.87e-06	2	48	2	25970345
Pubmed	Positive and negative modulation of human immunodeficiency virus type 1 Rev function by cis and trans regulators of viral RNA splicing.	SRSF1 SRSF2	1.87e-06	2	48	2	11967326
Pubmed	Dephosphorylation-dependent sorting of SR splicing factors during mRNP maturation.	SRSF1 SRSF2	1.87e-06	2	48	2	16285923
Pubmed	Two genes encode factors with NF-kappa B- and H2TF1-like DNA-binding properties.	HIVEP3 HIVEP2	1.87e-06	2	48	2	2247438
Pubmed	Gastrointestinal tract tumors and cell lines possess differential splicing factor expression and tumor associated mRNA isoform formation profiles.	SRSF1 SRSF2	1.87e-06	2	48	2	26406946
Pubmed	Liver-Specific Deletion of SRSF2 Caused Acute Liver Failure and Early Death in Mice.	SRSF1 SRSF2	1.87e-06	2	48	2	27022105
Pubmed	Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.	MEPCE RBM15B RBM5 CPSF1 TRA2A SRSF1 SRSF2 TRA2B TASOR	2.07e-06	847	48	9	35850772
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	RBM15B RBM5 CPSF1 TRA2A HIVEP1 SRSF1 SRSF2 TRA2B TRIO ACAD9 SEC23IP	2.94e-06	1425	48	11	30948266
Pubmed	A systematic screen for CDK4/6 substrates links FOXM1 phosphorylation to senescence suppression in cancer cells.	TRA2A SRSF1 SRSF2 TRA2B	3.24e-06	73	48	4	22094256
Pubmed	Charting the landscape of tandem BRCT domain-mediated protein interactions.	MEPCE RBM5 TRA2A PISD SRSF1 SRSF2 CUBN TRA2B	3.48e-06	670	48	8	22990118
Pubmed	The cellular EJC interactome reveals higher-order mRNP structure and an EJC-SR protein nexus.	TRA2A SRSF1 SRSF2 TRA2B EIF4B	3.69e-06	169	48	5	23084401
Pubmed	Dual effect of the SR proteins ASF/SF2, SC35 and 9G8 on HIV-1 RNA splicing and virion production.	SRSF1 SRSF2	5.59e-06	3	48	2	15907217
Pubmed	Novel mutations in ALOX12B in patients with autosomal recessive congenital ichthyosis and evidence for genetic heterogeneity on chromosome 17p13.	ALOX12B ALOX15B	5.59e-06	3	48	2	17139268
Pubmed	Identification of evolutionarily conserved exons as regulated targets for the splicing activator tra2β in development.	TRA2A TRA2B	5.59e-06	3	48	2	22194695
Pubmed	Dampening of death pathways by schnurri-2 is essential for T-cell development.	HIVEP3 HIVEP2	5.59e-06	3	48	2	21475200
Pubmed	NSrp70 is a novel nuclear speckle-related protein that modulates alternative pre-mRNA splicing in vivo.	SRSF1 SRSF2	5.59e-06	3	48	2	21296756
Pubmed	Casein Kinase 2 dependent phosphorylation of eIF4B regulates BACE1 expression in Alzheimer's disease.	BACE1 EIF4B	5.59e-06	3	48	2	34349120
Pubmed	A human importin-beta family protein, transportin-SR2, interacts with the phosphorylated RS domain of SR proteins.	SRSF1 TRA2B	5.59e-06	3	48	2	10713112
Pubmed	Tra2-mediated recognition of HIV-1 5' splice site D3 as a key factor in the processing of vpr mRNA.	TRA2A TRA2B	5.59e-06	3	48	2	23255807
Pubmed	Long non-coding RNA MIR205HG regulates KRT17 and tumor processes in cervical cancer via interaction with SRSF1.	SRSF1 KRT17	5.59e-06	3	48	2	31655037
Pubmed	Exon identity established through differential antagonism between exonic splicing silencer-bound hnRNP A1 and enhancer-bound SR proteins.	SRSF1 SRSF2	5.59e-06	3	48	2	11779509
Pubmed	Nuclear Speckle-related Protein 70 Binds to Serine/Arginine-rich Splicing Factors 1 and 2 via an Arginine/Serine-like Region and Counteracts Their Alternative Splicing Activity.	SRSF1 SRSF2	5.59e-06	3	48	2	26797131
Pubmed	Dynamic protein-protein interaction wiring of the human spliceosome.	RBM5 TRA2A SRSF1 SRSF2 TRA2B	7.79e-06	197	48	5	22365833
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	RBM15B TRA2A HIVEP1 TRA2B CLASP1 EIF4B	1.02e-05	361	48	6	26167880
Pubmed	cDNA cloning of a 8-lipoxygenase and a novel epidermis-type lipoxygenase from phorbol ester-treated mouse skin.	ALOX12B ALOX15B	1.12e-05	4	48	2	9518531
Pubmed	Specific interactions between proteins implicated in splice site selection and regulated alternative splicing.	SRSF1 SRSF2	1.12e-05	4	48	2	8261509
Pubmed	hnRNP A1 and the SR proteins ASF/SF2 and SC35 have antagonistic functions in splicing of beta-tropomyosin exon 6B.	SRSF1 SRSF2	1.12e-05	4	48	2	15208309
Pubmed	Dephosphorylated SRp38 acts as a splicing repressor in response to heat shock.	TRA2A TRA2B	1.12e-05	4	48	2	14765198
Pubmed	Hypophosphorylated ASF/SF2 binds TAP and is present in messenger ribonucleoproteins.	SRSF1 SRSF2	1.12e-05	4	48	2	15184380
Pubmed	Differential effects of the SR proteins 9G8, SC35, ASF/SF2, and SRp40 on the utilization of the A1 to A5 splicing sites of HIV-1 RNA.	SRSF1 SRSF2	1.12e-05	4	48	2	15123677
Pubmed	A gene cluster encoding human epidermis-type lipoxygenases at chromosome 17p13.1: cloning, physical mapping, and expression.	ALOX12B ALOX15B	1.12e-05	4	48	2	11350124
Pubmed	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.	MEPCE RBM15B RBM5 TRA2A SRSF1 SRSF2 TRA2B EIF4B	1.35e-05	807	48	8	22681889
Pubmed	Comprehensive proteomic analysis of the human spliceosome.	RBM5 CPSF1 SRSF1 SRSF2	1.60e-05	109	48	4	12226669
Pubmed	Deficiency of the splicing factor Sfrs10 results in early embryonic lethality in mice and has no impact on full-length SMN/Smn splicing.	SRSF2 TRA2B	1.86e-05	5	48	2	20190275
Pubmed	A differentially expressed murine RNA encoding a protein with similarities to two types of nucleic acid binding motifs.	SRSF1 SRSF2	1.86e-05	5	48	2	2030943
Pubmed	SRPK1 and Clk/Sty protein kinases show distinct substrate specificities for serine/arginine-rich splicing factors.	SRSF1 SRSF2	1.86e-05	5	48	2	8798720
Pubmed	SR proteins collaborate with 7SK and promoter-associated nascent RNA to release paused polymerase.	SRSF1 SRSF2	1.86e-05	5	48	2	23663783
Pubmed	Thr199 phosphorylation targets nucleophosmin to nuclear speckles and represses pre-mRNA processing.	SRSF1 SRSF2	1.86e-05	5	48	2	16376875
Pubmed	Identification and characterization of a novel serine-arginine-rich splicing regulatory protein.	SRSF1 SRSF2	1.86e-05	5	48	2	10757789
Pubmed	SR proteins induce alternative exon skipping through their activities on the flanking constitutive exons.	SRSF1 SRSF2	1.86e-05	5	48	2	21135118
Pubmed	Composition and three-dimensional EM structure of double affinity-purified, human prespliceosomal A complexes.	RBM5 SRSF1 SRSF2 TRA2B	1.97e-05	115	48	4	17332742
Pubmed	Lysine acetylation targets protein complexes and co-regulates major cellular functions.	SRSF1 SRSF2 TRA2B	2.01e-05	38	48	3	19608861
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	MEPCE HIVEP1 PFKFB2 HIVEP2 TRA2B TRIO CLASP1 EIF4B	2.14e-05	861	48	8	36931259
Pubmed	Interactome analyses revealed that the U1 snRNP machinery overlaps extensively with the RNAP II machinery and contains multiple ALS/SMA-causative proteins.	MEPCE TRA2A SRSF1 TRA2B TASOR	2.18e-05	244	48	5	29884807
Pubmed	Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.	MEPCE CPSF1 OAS1 SRSF1 SRSF2 TRA2B FMC1 LOX ACAD9 DDR2	2.38e-05	1451	48	10	30550785
Pubmed	The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation.	MEPCE TRA2A KRT20 RBMXL2 SRSF1 SRSF2 RBMXL3 KRT17 TRA2B	2.45e-05	1153	48	9	29845934
Pubmed	SETD1A Methyltransferase Is Physically and Functionally Linked to the DNA Damage Repair Protein RAD18.	RBM15B RBM5 CPSF1 TRA2A TRA2B	2.50e-05	251	48	5	31076518
Pubmed	Overlapping effects of different members of the FGF family on lens fiber differentiation in transgenic mice.	CRYBA2 CRYBB3	2.79e-05	6	48	2	9693140
Pubmed	SR proteins: a conserved family of pre-mRNA splicing factors.	SRSF1 SRSF2	2.79e-05	6	48	2	1577277
Pubmed	CIR, a corepressor of CBF1, binds to PAP-1 and effects alternative splicing.	SRSF1 SRSF2	2.79e-05	6	48	2	15652350
Pubmed	The beta crystallin genes on human chromosome 22 define a new region of homology with mouse chromosome 5.	CRYBA2 CRYBB3	2.79e-05	6	48	2	7789995
Pubmed	Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1.	MEPCE CPSF1 TRA2A SRSF1 SRSF2 TRA2B ACAD9	3.01e-05	653	48	7	33742100
Pubmed	TNIP2 is a Hub Protein in the NF-κB Network with Both Protein and RNA Mediated Interactions.	CPSF1 TRA2A RSRP1 SRSF1 SRSF2 TRA2B TRIO EIF4B	3.49e-05	922	48	8	27609421
Pubmed	Assignment of the beta B1 crystallin gene (CRYBB1) to human chromosome 22 and mouse chromosome 5.	CRYBA2 CRYBB3	3.90e-05	7	48	2	8575764
Pubmed	Srsf10 and the minor spliceosome control tissue-specific and dynamic SR protein expression.	SRSF1 SRSF2	3.90e-05	7	48	2	32338600
Pubmed	Systematic discovery of nonobvious human disease models through orthologous phenotypes.	FOLH1 SEC23IP	3.90e-05	7	48	2	20308572
Pubmed	Sip1, a novel RS domain-containing protein essential for pre-mRNA splicing.	SRSF1 SRSF2	3.90e-05	7	48	2	9447963
Pubmed	Functional properties of p54, a novel SR protein active in constitutive and alternative splicing.	SRSF1 SRSF2	3.90e-05	7	48	2	8816452
Pubmed	A protein related to splicing factor U2AF35 that interacts with U2AF65 and SR proteins in splicing of pre-mRNA.	SRSF1 SRSF2	3.90e-05	7	48	2	9237760
Pubmed	The protein interaction landscape of the human CMGC kinase group.	MEPCE CPSF1 TRA2A RSRP1 SRSF1 SRSF2 TRA2B	4.46e-05	695	48	7	23602568
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	MEPCE RBM15B CPSF1 TRA2A PISD SRSF1 KRT17 TRA2B EIF4B	4.81e-05	1257	48	9	36526897
Pubmed	Spatial mapping of splicing factor complexes involved in exon and intron definition.	SRSF1 SRSF2	5.19e-05	8	48	2	18559666
Pubmed	SAF-B protein couples transcription and pre-mRNA splicing to SAR/MAR elements.	SRSF1 TRA2B	5.19e-05	8	48	2	9671816
Pubmed	Genetic Associations with Plasma B12, B6, and Folate Levels in an Ischemic Stroke Population from the Vitamin Intervention for Stroke Prevention (VISP) Trial.	FUT2 CUBN	5.19e-05	8	48	2	25147783
Pubmed	Genome-wide association study of vitamin B6, vitamin B12, folate, and homocysteine blood concentrations.	FUT2 CUBN	5.19e-05	8	48	2	19303062
Pubmed	RNA-binding proteins with basic-acidic dipeptide (BAD) domains self-assemble and aggregate in Alzheimer's disease.	MEPCE RBM15B CPSF1 TRA2A SRSF1 SRSF2 TRA2B	5.24e-05	713	48	7	29802200
Pubmed	Proteomic analysis of the cullin 4B interactome using proximity-dependent biotinylation in living cells.	TRA2A RBMXL2 RBMXL3 TRA2B	6.03e-05	153	48	4	28225217
Pubmed	NLRP7 deubiquitination by USP10 promotes tumor progression and tumor-associated macrophage polarization in colorectal cancer.	SRSF1 SRSF2 KRT17 EIF4B	6.34e-05	155	48	4	33838681
Pubmed	microRNA-mediated regulation of splicing factors SRSF1, SRSF2 and hnRNP A1 in context of their alternatively spliced 3'UTRs.	SRSF1 SRSF2	6.67e-05	9	48	2	29331391
Pubmed	The SR protein family.	SRSF1 SRSF2	6.67e-05	9	48	2	19857271
Pubmed	ZNF265--a novel spliceosomal protein able to induce alternative splicing.	SRSF2 TRA2B	6.67e-05	9	48	2	11448987
Pubmed	Genome-wide significant predictors of metabolites in the one-carbon metabolism pathway.	FUT2 CUBN	6.67e-05	9	48	2	19744961
Pubmed	Regulation of alternative splicing by SRrp86 and its interacting proteins.	SRSF1 SRSF2 TRA2B	6.85e-05	57	48	3	14559993
Pubmed	New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing.	CPSF1 PFKFB2 SRSF1 SRSF2 TRIO DDR2	7.26e-05	513	48	6	25798074
Pubmed	Conserved expression of ultra-conserved noncoding RNA in mammalian nervous system.	TRA2A SRSF1 TRA2B	7.99e-05	60	48	3	29055695
Pubmed	The RNA recognition motif protein RBM11 is a novel tissue-specific splicing regulator.	SRSF1 SRSF2	8.33e-05	10	48	2	21984414
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	RBM15B CPSF1 RBMXL2 HIVEP1 SRSF2 CLASP1 EIF4B	8.76e-05	774	48	7	15302935
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	RBM15B RBM5 CPSF1 TRA2A SRSF1 SRSF2 RBMXL3 CLASP1 LOX	9.37e-05	1371	48	9	36244648
Pubmed	The upstream ectoderm enhancer in Pax6 has an important role in lens induction.	CRYBA2 CRYBB3	1.02e-04	11	48	2	11714668
Pubmed	Disruption of Trkb-mediated signaling induces disassembly of postsynaptic receptor clusters at neuromuscular junctions.	CRYBA2 CRYBB3	1.02e-04	11	48	2	10595510
Pubmed	SRPK2: a differentially expressed SR protein-specific kinase involved in mediating the interaction and localization of pre-mRNA splicing factors in mammalian cells.	SRSF1 SRSF2	1.02e-04	11	48	2	9472028
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	RBM15B RBM5 CPSF1 TRA2A SRSF1 SRSF2 TRA2B CLASP1	1.07e-04	1082	48	8	38697112
Interaction	CLK2 interactions	MEPCE CPSF1 TRA2A RSRP1 SRSF1 TRA2B	6.65e-06	195	48	6	int:CLK2
Interaction	RBMX interactions	MEPCE TRA2A RBMXL2 SRSF1 SRSF2 TRA2B EIF4B SEC23IP	1.19e-05	461	48	8	int:RBMX
Interaction	SRSF9 interactions	TRA2A LTK SRSF1 SRSF2 TRA2B EIF4B	1.47e-05	224	48	6	int:SRSF9
Interaction	TRA2B interactions	MEPCE CPSF1 TRA2A RBMXL2 SRSF1 SRSF2 TRA2B	3.30e-05	385	48	7	int:TRA2B
Interaction	SRPK2 interactions	RBM15B TRA2A RSRP1 HIVEP1 SRSF1 SRSF2 TRA2B CLASP1 EIF4B	4.20e-05	717	48	9	int:SRPK2
Interaction	SRSF4 interactions	MEPCE RBM5 TRA2A SRSF1 SRSF2 TRA2B	7.51e-05	300	48	6	int:SRSF4
Interaction	AIRE interactions	SRSF1 SRSF2 ALOX12B PICK1	8.34e-05	97	48	4	int:AIRE
Interaction	DOT1L interactions	MEPCE RBM15B RBM5 CPSF1 TRA2A SRSF1 SRSF2 TRA2B TASOR	1.04e-04	807	48	9	int:DOT1L
Interaction	MIRLET7E interactions	RBM5 CPSF1 TRA2A TRA2B	1.18e-04	106	48	4	int:MIRLET7E
Interaction	SNRPA interactions	CPSF1 TRA2A LTK SRSF1 SRSF2 TRA2B TASOR	1.35e-04	482	48	7	int:SNRPA
Interaction	MIRLET7I interactions	RBM5 CPSF1 TRA2A TRA2B	1.56e-04	114	48	4	int:MIRLET7I
Interaction	SRRM1 interactions	CPSF1 TRA2A CRYBB3 SRSF1 SRSF2 TRA2B	1.69e-04	348	48	6	int:SRRM1
Interaction	CLK1 interactions	TRA2A HIVEP1 SRSF1 SRSF2 TRA2B	1.69e-04	219	48	5	int:CLK1
Interaction	MIRLET7G interactions	RBM5 CPSF1 TRA2A TRA2B	1.72e-04	117	48	4	int:MIRLET7G
Interaction	CLK3 interactions	MEPCE TRA2A RSRP1 SRSF1 TRA2B	1.73e-04	220	48	5	int:CLK3
Interaction	SRSF6 interactions	MEPCE RBM5 TRA2A SRSF1 SRSF2 KRT17 TRA2B	1.76e-04	503	48	7	int:SRSF6
Cytoband	3p14.3	CACNA1D TASOR	4.57e-04	30	48	2	3p14.3
Cytoband	12q13.13	EIF4B FIGNL2	2.27e-03	67	48	2	12q13.13
Cytoband	17q21.2	KRT20 KRT17	2.47e-03	70	48	2	17q21.2
Cytoband	Ensembl 112 genes in cytogenetic band chr3p21	RBM15B RBM5 CACNA1D	4.44e-03	316	48	3	chr3p21
Cytoband	17p13.1	ALOX12B ALOX15B	6.84e-03	118	48	2	17p13.1
GeneFamily	RNA binding motif containing	RBM15B RBM5 TRA2A RBMXL2 SRSF1 SRSF2 RBMXL3 TRA2B EIF4B	1.50e-10	213	34	9	725
GeneFamily	Arachidonate lipoxygenases	ALOX12B ALOX15B	5.12e-05	6	34	2	407
GeneFamily	RNA binding motif containing\|Serine and arginine rich splicing factors	SRSF1 SRSF2	2.24e-04	12	34	2	737
GeneFamily	Beta-gamma crystallins	CRYBA2 CRYBB3	3.55e-04	15	34	2	1359
GeneFamily	Keratins, type I	KRT20 KRT17	1.26e-03	28	34	2	608
GeneFamily	Receptor Tyrosine Kinases\|CD molecules	LTK DDR2	2.56e-03	40	34	2	321
ToppCell	Adult-Epithelial-basal_cell-D175\|Adult / Lineage, Cell type, age group and donor	CRYBB3 FLRT1 KRT17 FIGNL2	2.23e-05	153	48	4	9ee3e7f3f19a2474283c1c79045269686f35a541
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Myeloid-Granulocytic-Neutrophil-Neu_c3-CST7\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	MEPCE CA12 OAS1 NFE2	2.65e-05	160	48	4	913e59cecf3b1bdd1ef32b4e320042b9bbdb54bc
ToppCell	wk_15-18-Epithelial-Proximal_epithelial-SMG_basal_2\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	CA12 FUT2 KRT17 ALOX12B	3.85e-05	176	48	4	045b12c90f7dd49a9778dadcdf8f18125b380531
ToppCell	facs-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KRT20 FLRT1 CUBN LOX	3.94e-05	177	48	4	d68132e145bd413404fdbe215b5dbe520e756e50
ToppCell	COPD-Myeloid-pDC\|Myeloid / Disease state, Lineage and Cell class	HIVEP3 HIVEP1 PFKFB2 PTPRS	4.11e-05	179	48	4	29b058c5e33fda9f0d738c074bdb67ff16b9b6d5
ToppCell	Control-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	HIVEP3 CACNA1D FOLH1 DDR2	4.20e-05	180	48	4	08ae0f5d95c45feba68ad99788f7af7ff4c979af
ToppCell	COVID-19_Mild-CD4+_T_activated\|COVID-19_Mild / Disease condition and Cell class	REX1BD OAS1 RSRP1 HIVEP2	4.39e-05	182	48	4	877b6e611626628e709568747512f2827ebb2795
ToppCell	E18.5-samps-Mesenchymal-Matrix_fibroblast\|E18.5-samps / Age Group, Lineage, Cell class and subclass	HIVEP3 CACNA1D PTPRS LOX	4.39e-05	182	48	4	ceb37c214662a48efb56ab0d015977c6fab478b0
ToppCell	(00)_Basal-(4)_1wkpi\|(00)_Basal / shred by cell type and Timepoint	TRA2A RSRP1 KRT17 TRA2B	4.67e-05	185	48	4	bf82ba905e5eee1c39a2731702071d3de10a78b8
ToppCell	E16.5-samps-Mesenchymal\|E16.5-samps / Age Group, Lineage, Cell class and subclass	CACNA1D PTPRS LOX DDR2	4.98e-05	188	48	4	3f0f662be684e3a4c6652e636cc135a39a1d2790
ToppCell	droplet-Limb_Muscle-nan-3m-Endothelial-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RBM15B FUT2 CLASP1 PICK1	5.08e-05	189	48	4	16a4c92dd7a0d60f3691bd3130a091a9a54730f1
ToppCell	ILEUM-non-inflamed-(1)_T_cell-(1)_CD8_Trm\|(1)_T_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	TRA2A RSRP1 SRSF2 TRA2B	5.08e-05	189	48	4	2c8a2fb76ea002bac554bc1c761ce960b5e116e1
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	HIVEP3 CACNA1D LOX DDR2	5.18e-05	190	48	4	45df8fee00f8949937863159d7aa042e72748d9b
ToppCell	E16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal\|E16.5-samps / Age Group, Lineage, Cell class and subclass	HIVEP3 CACNA1D PTPRS LOX	5.29e-05	191	48	4	3379d145d34f89150f7b06d1340022cfc6b4a6ce
ToppCell	PND01-03-samps-Mesenchymal-Matrix_fibroblast-MatrixFB-A\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	HIVEP3 CACNA1D PTPRS LOX	5.29e-05	191	48	4	e7c605b56934d1383237c1f946dbccef25d91368
ToppCell	H1299-infected\|H1299 / Cell line, Condition and Strain	RBM5 CPSF1 RSRP1 SRSF2	5.40e-05	192	48	4	9cf8049bdc3e0f81ce69042beac72b08d8f38b4e
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	HIVEP3 CACNA1D PTPRS DDR2	5.51e-05	193	48	4	b3ad5ff480d99217f36cc7471e5a96a519ddb409
ToppCell	NS-critical-d_07-13-Epithelial-Secretory\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CA12 FUT2 PTPRS LOX	5.62e-05	194	48	4	2172d951896265243d14996eacce5aab5e14e26e
ToppCell	BL-critical-LOC-Epithelial-Basal\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CA12 KRT17 PTPRS LOX	5.62e-05	194	48	4	2932f704656ca368565ec12f3452af3b18e8df12
ToppCell	PND01-Mesenchymal-Mesenchymal_structural\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	HIVEP3 CACNA1D RSRP1 LOX	5.73e-05	195	48	4	6bb6349d6ec8da094fe1c7c590021989337aeb0b
ToppCell	PND01-Mesenchymal-Mesenchymal_structural-Fibroblastic\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	HIVEP3 CACNA1D RSRP1 LOX	5.73e-05	195	48	4	a3b468125e48f072255cede7645f6692298ecf54
ToppCell	droplet-Tongue-TONGUE\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CA12 CRYBA2 RSRP1 SRSF2	5.85e-05	196	48	4	44a30b1a5f3d8c845e5f3bd17d8102a7449f555b
ToppCell	droplet-Tongue-TONGUE-1m\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CA12 CRYBA2 RSRP1 SRSF2	5.85e-05	196	48	4	9935bdb10789e8cfc922dca526ca3bf8317fe270
ToppCell	droplet-Tongue-TONGUE-1m-Epithelial\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CA12 CRYBA2 RSRP1 SRSF2	5.85e-05	196	48	4	a85f5f1e6acc798e9e02b1a21e0ffe87a323c333
ToppCell	PND01-03-samps-Mesenchymal-Matrix_fibroblast\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	HIVEP3 CACNA1D PTPRS LOX	5.85e-05	196	48	4	54f4cf778f95a9ff662e5c7520916a25e605bf95
ToppCell	PND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	HIVEP3 CACNA1D RSRP1 LOX	5.97e-05	197	48	4	06a0d7062dadda656decaf77dcef9a10b5f2698d
ToppCell	Bronchus_Control_(B.)\|World / Sample group, Lineage and Cell type	HIVEP1 HIVEP2 FUT2 KRT17	5.97e-05	197	48	4	b6dff2ee108813e18657e2d8cf850e2423f8c8e9
ToppCell	PND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	HIVEP3 CACNA1D RSRP1 LOX	5.97e-05	197	48	4	d35c7a36135b5ed6a7bf2f934849678eba2a0177
ToppCell	Posterior_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_2-Mgp-Endothelial_Tip.Dcn.Mgp-Clu_(Clu)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	FUT2 CUBN NFE2	1.52e-04	96	48	3	9a1da3809073a4321134bf3767e0a40398b69caa
ToppCell	Frontal_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_2-Endothelial_Tip.Dcn.Dapl1_(Dapl1)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	FUT2 CUBN KRT17	2.04e-04	106	48	3	7079111add27d7b3411dfe739280d62dc256a174
ToppCell	Frontal_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_2-Endothelial_Tip.Dcn.Dapl1_(Dapl1)-\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	FUT2 CUBN KRT17	2.04e-04	106	48	3	a6334b67be05f78145b57271b7959471b80bd67f
ToppCell	PBMC-Severe-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-1\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	KRT20 RSRP1 HLA-DQB2	4.14e-04	135	48	3	7743a01dc9c4542e910e7c0fe046004692a680bf
ToppCell	Club_cells-IPF_04\|World / lung cells shred on cell class, cell subclass, sample id	FUT2 KRT17 LOX	4.41e-04	138	48	3	133015953fc660d00339f47b415da5e9872313a2
ToppCell	facs-Lung-EPCAM-3m-Hematologic-leukocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CA12 KRT20 NFE2	4.60e-04	140	48	3	731b46e4b815a45af1d0ce7ab4d0d0324ac8798f
ToppCell	facs-Lung-EPCAM-3m-Hematologic-Proliferating_Immune\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CA12 KRT20 NFE2	4.60e-04	140	48	3	b30fc389583406ee6cb55112d0f7250d1b74c88a
ToppCell	facs-Lung-EPCAM-3m-Hematologic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CA12 KRT20 NFE2	4.60e-04	140	48	3	35ecd887bb7827603ef673912ba820208a6368d2
ToppCell	Control-B_intermediate-1\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	REX1BD RSRP1 HLA-DQB2	5.00e-04	144	48	3	984470ff6ddce4c743e2db78fa98dae055aaa273
ToppCell	mild_COVID-19_(asymptomatic)-MAIT\|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)	LTK ALOX12B DDR2	5.96e-04	153	48	3	26852f3d8f80e102e24bcb90e24aac26fdc9a32c
ToppCell	Control-B_naive-1\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	REX1BD RSRP1 HLA-DQB2	6.19e-04	155	48	3	0a78d1cab2bdba2dc8a74cdf35b5a0192370c4b5
ToppCell	droplet-Liver-LIVER_NPC-30m-Myeloid-plasmacytoid_dendritic_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HIVEP3 CACNA1D PTPRS	6.43e-04	157	48	3	fc127e7720649e746f3d3f5c2e9e63784767106a
ToppCell	droplet-Liver-LIVER_NPC-30m-Myeloid-plasmacytoid_dendritic_cells\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HIVEP3 CACNA1D PTPRS	6.43e-04	157	48	3	66a191cef4aa00811bb04462310d012610006f85
ToppCell	severe_COVID-19-pDC\|World / disease group, cell group and cell class (v2)	LTK PTPRS ALOX15B	6.67e-04	159	48	3	e1c48c4ceda116826819ff9adeed7bad6a58844d
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CA12 CACNA1D KRT17	6.79e-04	160	48	3	2d391ba6f7adb55dfa89feecc10cc9ce97e5fe74
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CA12 CACNA1D KRT17	6.79e-04	160	48	3	8bcdbcfdf1e0ace6053e8de82762f6e2f86bba7a
ToppCell	saliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage-macrophage,_alveolar-Macro_c2-CCL3L1\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	FUT2 TASOR PTPRS	7.16e-04	163	48	3	130c84bca3f72ab7d1a4fee2990c3d01600318ed
ToppCell	BAL-Mild-cDC_0\|Mild / Compartment, Disease Groups and Clusters	MEPCE RBM15B NFE2	7.16e-04	163	48	3	7047d3ba847930f42a6d5f71e18d49f3071c6409
ToppCell	wk_20-22-Hematologic-Myeloid-HSC\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	NFE2 ALOX12B ALOX15B	7.29e-04	164	48	3	a35a0725b8bfe3cad5b85484217fd8a02bdee827
ToppCell	367C-Myeloid-Dendritic-pDC\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	LTK CUBN PTPRS	7.29e-04	164	48	3	95b800c78871354c859abaa832d778786ef7bcc0
ToppCell	E18.5-samps-Mesenchymal-Matrix_fibroblast-MatrixFB-A\|E18.5-samps / Age Group, Lineage, Cell class and subclass	CACNA1D PTPRS LOX	7.29e-04	164	48	3	519ab4fe885dfe4c50846f346a062acc2cb44299
ToppCell	PBMC-Severe-Lymphocyte-B-B_cell-B_naive-B_naive-1\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	RSRP1 TRIO HLA-DQB2	7.42e-04	165	48	3	fead3f2032f8fa5f7f0159a4434989b3d65debbb
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-DC-DC1-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	HIVEP1 PFKFB2 LTK	7.55e-04	166	48	3	c8a7d94ed762e5e045ab5f74eef691ddc5f74993
ToppCell	5'-Adult-SmallIntestine-Epithelial-goblet-BEST2+_Goblet_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KRT20 OAS1 LTK	7.55e-04	166	48	3	0b4e1d879c61be9d18d7aac51e5115f103f51209
ToppCell	367C-Myeloid-Dendritic-pDC\|367C / Donor, Lineage, Cell class and subclass (all cells)	HIVEP1 LTK PTPRS	7.68e-04	167	48	3	650de8cd5df070639b8aa292aacead739cfdb02c
ToppCell	Control-B_intermediate-1\|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)	REX1BD RSRP1 HLA-DQB2	7.68e-04	167	48	3	948504367ecf58144d9dd74d2ec531358fc4b309
ToppCell	facs-Skin-Anagen-24m-Epithelial-bulge_keratinocyte\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLRT1 KRT17 PTPRS	7.68e-04	167	48	3	78909f685ccd1321064eb0887caf9263e0e54879
ToppCell	metastatic_Brain-Myeloid_cells-pDCs\|Myeloid_cells / Location, Cell class and cell subclass	HIVEP1 LTK PTPRS	7.82e-04	168	48	3	4bf3f85aac4b335efa93d22c9ce7b153cb5ce152
ToppCell	3'_v3-blood-Lymphocytic_B-ABC_aged-B_memory\|blood / Manually curated celltypes from each tissue	OAS1 LTK HLA-DQB2	7.82e-04	168	48	3	2ce1a30feb2704a9516d1dab161a26cb0555abb5
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Neuronal-neurons_A\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FLRT1 CLASP1 PTPRS	7.95e-04	169	48	3	606aa4ff25380d9470ec116ca86cd20f8b19587a
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Neuronal-neurons_A-Branch_A1_(iMN)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FLRT1 CLASP1 PTPRS	7.95e-04	169	48	3	052aae2af5446a0de071d5dda5381b0b9a0ed54d
ToppCell	367C-Myeloid-Dendritic-pDC\|Dendritic / Donor, Lineage, Cell class and subclass (all cells)	LTK CUBN PTPRS	8.09e-04	170	48	3	fbb7019c6fba87326702b51f6819ea1af5f3a9b7
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-papillary_tips_cell-Papillary_Tip_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	OAS1 FUT2 KRT17	8.23e-04	171	48	3	59b9dbaa05b6e5740edc633c9ce1181565550d5b
ToppCell	Control-B_naive-1\|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)	REX1BD RSRP1 HLA-DQB2	8.23e-04	171	48	3	d18855b24aadea38fd1e4592f945cf15b85e05f1
ToppCell	3'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature-ENCC/glia_Progenitor\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RBM15B FLRT1 CLASP1	8.23e-04	171	48	3	b51bbeacb172e8b5de519ada85543d7ae9914b3c
ToppCell	COVID_vent-Lymphocytic-Dendritic-pDC\|COVID_vent / Disease condition, Lineage, Cell class and subclass	PFKFB2 LTK PTPRS	8.23e-04	171	48	3	779c951d274ecbd1d546ac425d6c8e718623be5a
ToppCell	COVID_vent-Lymphocytic-Dendritic\|COVID_vent / Disease condition, Lineage, Cell class and subclass	PFKFB2 LTK PTPRS	8.23e-04	171	48	3	debbb071d260639b16269c94d172766908325c58
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-papillary_tips_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	OAS1 FUT2 KRT17	8.23e-04	171	48	3	a5b9dd2b6a54db7962beeb5a9ceb9dacfb613fa7
ToppCell	3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TRIO LOX DDR2	8.37e-04	172	48	3	e37c0b5b547a7345179ab258dd2141fec7064c17
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.4\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	OAS1 FUT2 LOX	8.51e-04	173	48	3	176b956e71d98e8275d698b39437fc326e5fe449
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Epithelial-epithelial_progenitor_cell-Distal_progenitor\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CA12 CACNA1D FUT2	8.51e-04	173	48	3	81c36b9fe02c59099f080b2db02f4eaf2783911f
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L5-6_FEZF2_ANKRD20A1\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	HIVEP1 KRT17 DDR2	8.65e-04	174	48	3	99eb5e1aee136c7039e23b68a43a0fa3d775859f
ToppCell	COPD-Myeloid-pDC\|World / Disease state, Lineage and Cell class	HIVEP1 PFKFB2 PTPRS	8.65e-04	174	48	3	be8227398300711ccda5ecc41ad34064bb246b19
ToppCell	severe_influenza-pDC\|severe_influenza / disease group, cell group and cell class (v2)	PFKFB2 LTK PTPRS	8.65e-04	174	48	3	d8d2ded5812ed3b3db4109585714a6513c13326a
ToppCell	mild_COVID-19-pDC\|mild_COVID-19 / disease group, cell group and cell class (v2)	PFKFB2 LTK PTPRS	8.80e-04	175	48	3	b87f279a7519710146c49d6acccb0adedc195965
ToppCell	3'-Parenchyma_lung-Epithelial-Epithelial_transtional-epithelial_cell_of_lung-Transitional_Club-AT2-Transitional_Club-AT2_L.0.4.1.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	HIVEP1 TRIO ALOX15B	8.80e-04	175	48	3	dbd9dac129fb6ae5f55e7b96d04b37585458dc4a
ToppCell	IPF-Myeloid-pDC\|World / Disease state, Lineage and Cell class	HIVEP1 PFKFB2 PTPRS	8.80e-04	175	48	3	a06785a4ded01adfd29ca4c20f7759eccbe274cb
ToppCell	ILEUM-inflamed-(3)_pDC\|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	HIVEP1 PFKFB2 PTPRS	8.94e-04	176	48	3	b9f847dd55703e413f3cd815eef5724fffaf13b3
ToppCell	10x3'2.3-week_17-19-Mesenchymal_osteo-stroma-chondrocyte\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	CA12 CRYBA2 DDR2	9.09e-04	177	48	3	915b848d789051a1c3bc6f6dc86955bb752276ab
ToppCell	COPD-Myeloid-pDC\|COPD / Disease state, Lineage and Cell class	HIVEP1 PFKFB2 PTPRS	9.09e-04	177	48	3	415aa023195a7f961c09529f65cdcc7bb90eaf5d
ToppCell	IPF-Myeloid-pDC\|IPF / Disease state, Lineage and Cell class	HIVEP1 PFKFB2 PTPRS	9.24e-04	178	48	3	8d9e28492e1f157bac3308aa947fd864ca16d277
ToppCell	Control-Myeloid-pDC\|World / Disease state, Lineage and Cell class	HIVEP1 PFKFB2 PTPRS	9.24e-04	178	48	3	20ef63d925e67ddd5955832312ca8574a6f838a4
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Dendritic-plasmacytoid_dendritic_cell\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	PFKFB2 LTK PTPRS	9.39e-04	179	48	3	124da6f882968dc0d05f3edd8f3b4d61617cc214
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Dendritic-plasmacytoid_dendritic_cell-DC_c4-LILRA4\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	PFKFB2 LTK PTPRS	9.39e-04	179	48	3	edc5ef693dc4e7ea70717b77fb908fc784dce3a2
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_prolif\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	HIVEP3 CACNA1D LOX	9.39e-04	179	48	3	948c2a01ec7a626c68281e6e796a9f0527a88591
ToppCell	IPF-Myeloid-pDC\|Myeloid / Disease state, Lineage and Cell class	HIVEP1 PFKFB2 PTPRS	9.54e-04	180	48	3	0f8567aa835d4e3a52f6631ae15216eca18a030c
ToppCell	mild-Myeloid-pDC\|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	PFKFB2 LTK PTPRS	9.54e-04	180	48	3	38614155fa537d0defda914c531c697be0ef06d8
ToppCell	facs-Lung-24m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RBM15B LOX SEC23IP	9.54e-04	180	48	3	baa5825e6ce23a98d9c21d024a4b0ab8ba353d0c
ToppCell	3'_v3-bone_marrow-Myeloid_Mac-Erythrophagocytic_macrophages\|bone_marrow / Manually curated celltypes from each tissue	OAS1 PFKFB2 ALOX15B	9.54e-04	180	48	3	daf69a548ed7c6f285a6adcff00f99aa22f9d6a5
ToppCell	facs-Marrow-B-cells-3m-Myeloid-CD4+_macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HIVEP3 CACNA1D PTPRS	9.54e-04	180	48	3	bf8d13d4db1af55b8c9fe16aaccf8743e000e005
ToppCell	facs-Marrow-B-cells-3m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HIVEP3 CACNA1D PTPRS	9.54e-04	180	48	3	839defb40f7cfb2711e9025194de636533f51bcd
ToppCell	facs-Lung-24m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RBM15B LOX SEC23IP	9.54e-04	180	48	3	2d608b9394d28d19cfc85c6ac94003d5177c8a92
ToppCell	facs-Marrow-B-cells-3m-Myeloid-macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HIVEP3 CACNA1D PTPRS	9.54e-04	180	48	3	82965ed1b72a1873c24dd4553d39681596057316
ToppCell	Control-Stromal_mesenchymal-Matrix_Fibroblast\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNA1D LOX DDR2	9.54e-04	180	48	3	9b1de1b4711adbf9a423f4d2d08f3f4c78f1f8f4
ToppCell	facs-Lung-24m-Endothelial-arterial_endothelial\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RBM15B LOX SEC23IP	9.54e-04	180	48	3	0f9b27054358c4737eed06c8ea01987cccc3cb55
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia/MHC-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CUBN TRIO PTPRS	9.54e-04	180	48	3	e4add4c94f892a2d93926e5c6dac6a738319d091
ToppCell	3'_v3-blood-Myeloid_Dendritic-pDC\|blood / Manually curated celltypes from each tissue	HIVEP1 PFKFB2 PTPRS	9.70e-04	181	48	3	66d890a105f955dca91d6e5e6c730d1a68ee9233
ToppCell	Control-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNA1D LOX DDR2	9.70e-04	181	48	3	9e7d0f1afb8d9bc5a209ddb5314df3a25a0274d9
ToppCell	facs-Pancreas-Exocrine-18m-Mesenchymal\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FOLH1 LOX DDR2	9.70e-04	181	48	3	269b39ac65790061d54eab47a8eeb024403f0348
ToppCell	facs-Marrow-T-cells-3m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TASOR PTPRS ALOX15B	9.70e-04	181	48	3	7286700396676fdc41d9723979b8b408177aceb9
ToppCell	facs-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FOLH1 LOX DDR2	9.70e-04	181	48	3	cd4f744b6b64ba6c22ec07afd1d3058a2546909d
ToppCell	3'_v3-Lung-Myeloid_Dendritic-pDC\|Lung / Manually curated celltypes from each tissue	PFKFB2 LTK PTPRS	9.70e-04	181	48	3	3d7f089fb434fbc989f1fa159e22133ae00b2487
Computational	Neighborhood of HDAC1	TRA2A SRSF1 SRSF2 TRA2B EIF4B	2.60e-05	110	35	5	GNF2_HDAC1
Computational	RNA splicing.	RBM5 SRSF1 SRSF2 TRA2B	5.54e-05	65	35	4	MODULE_183
Computational	Neighborhood of TDG	SRSF1 SRSF2 TRA2B	1.93e-04	35	35	3	GNF2_TDG
Computational	Neighborhood of ANP32B	SRSF1 SRSF2 TRA2B	2.28e-04	37	35	3	GNF2_ANP32B
Drug	retinoic acid; Down 200; 1uM; HL60; HG-U133A	CA12 CACNA1D LTK CUBN TRIO ALOX15B DDR2	1.72e-07	196	48	7	390_DN
Drug	colneleic acid	LOX ALOX12B ALOX15B	4.89e-07	8	48	3	CID006441681
Drug	13-hydroxylinoleic acid	LOX ALOX12B ALOX15B	7.32e-07	9	48	3	CID006438633
Drug	AC1NSXHC	LOX ALOX12B ALOX15B	7.32e-07	9	48	3	CID005371969
Drug	ODYA	LOX ALOX12B ALOX15B	7.32e-07	9	48	3	CID000001931
Drug	AC1L1AUZ	TRA2A KRT20 RBMXL2 SRSF1 SRSF2 SEC23IP	9.44e-07	157	48	6	CID000001160
Drug	REV 5901	KRT17 LOX ALOX12B ALOX15B	1.35e-06	39	48	4	CID000005059
Drug	oxphaman	LOX ALOX12B ALOX15B	3.15e-06	14	48	3	CID005464022
Drug	estradiol, USP; Down 200; 0.01uM; HL60; HG-U133A	LTK SRSF1 CUBN TRIO LOX DDR2	3.63e-06	198	48	6	387_DN
Drug	8R-HpETE	LOX ALOX12B ALOX15B	3.93e-06	15	48	3	CID005283170
Drug	Hex-3-enyl acetate	LOX ALOX12B ALOX15B	3.93e-06	15	48	3	CID000015574
Drug	13-HpOTrE	LOX ALOX12B ALOX15B	3.93e-06	15	48	3	CID005282866
Drug	12R-HETrE	LOX ALOX12B ALOX15B	4.83e-06	16	48	3	CID005283149
Drug	peroxylinolenic acid	LOX ALOX12B ALOX15B	4.83e-06	16	48	3	CID006439905
Drug	hex-3-enal	LOX ALOX12B ALOX15B	4.83e-06	16	48	3	CID000023234
Drug	AC1O5PL5	LOX ALOX12B ALOX15B	7.02e-06	18	48	3	CID006438380
Drug	1lox	LOX ALOX15B	1.30e-05	3	48	2	CID010308106
Drug	N-benzyl-N-hydroxy-5-phenylpentamide	LOX ALOX12B ALOX15B	1.51e-05	23	48	3	CID000157806
Drug	13-hydroperoxylinoleic acid	LOX ALOX12B ALOX15B	1.96e-05	25	48	3	CID006438144
Drug	(+/-)-Jasmonic Acid	HIVEP2 FOLH1 LOX ALOX12B ALOX15B	2.03e-05	158	48	5	CID000105087
Drug	AC1L3WDO	LOX ALOX12B ALOX15B	2.21e-05	26	48	3	CID000123344
Drug	8-HETE	LOX ALOX12B ALOX15B	2.21e-05	26	48	3	CID000001898
Drug	Bhpp	LOX ALOX12B ALOX15B	2.48e-05	27	48	3	CID000164136
Drug	AC1L1G9E	LOX ALOX12B ALOX15B	2.78e-05	28	48	3	CID000003586
Drug	13-epi-12-oxo-phytodienoic acid	LOX ALOX12B ALOX15B	3.09e-05	29	48	3	CID000188366
Drug	AC1NRA5C	TRA2A RBMXL2 SRSF1 SRSF2 TRA2B	3.23e-05	174	48	5	CID005287709
Drug	neoR	PISD LTK NFE2 LOX	3.25e-05	86	48	4	CID000496913
Drug	eicosa-8,11,14-trienoic acid	LOX ALOX12B EIF4B ALOX15B	3.56e-05	88	48	4	CID000003011
Drug	12-hydroxyheptadecatrienoic acid	LOX ALOX12B ALOX15B	3.79e-05	31	48	3	CID000001414
Drug	Ellipticine [519-23-3]; Up 200; 16.2uM; HL60; HG-U133A	RSRP1 AREL1 PISD HIVEP1 SEC23IP	4.22e-05	184	48	5	1765_UP
Drug	14-hydroxydocosahexaenoic acid	ALOX12B ALOX15B	4.33e-05	5	48	2	CID006439735
Drug	artonin E	ALOX12B ALOX15B	4.33e-05	5	48	2	CID005481962
Drug	CP-645525-01 [287190-82-3]; Down 200; 10uM; MCF7; HT_HG-U133A	HIVEP3 TRA2A PFKFB2 TRIO SEC23IP	5.42e-05	194	48	5	7515_DN
Drug	Furaltadone hydrochloride [3759-92-0]; Down 200; 11uM; MCF7; HT_HG-U133A	CACNA1D PFKFB2 HIVEP2 SRSF1 TRIO	5.42e-05	194	48	5	3932_DN
Drug	PF-00539745-00 [351321-33-0]; Down 200; 10uM; MCF7; HT_HG-U133A	RBM5 CACNA1D PFKFB2 LTK PTPRS	5.70e-05	196	48	5	5974_DN
Drug	HNMPA-(AM)3; Down 200; 5uM; PC3; HG-U133A	RBM5 CPSF1 TRA2A PISD FUT2	5.83e-05	197	48	5	583_DN
Drug	radicicol; Down 200; 0.1uM; PC3; HG-U133A	HIVEP3 CACNA1D TRA2A SRSF1 TRIO	5.83e-05	197	48	5	449_DN
Drug	Remoxipride Hydrochloride [73220-03-8]; Up 200; 9.8uM; PC3; HT_HG-U133A	CACNA1D TRA2A PISD LOX PICK1	6.12e-05	199	48	5	6342_UP
Drug	sulindac sulfone; Up 200; 50uM; MCF7; HG-U133A	HIVEP3 CPSF1 SRSF1 FUT2 TRIO	6.12e-05	199	48	5	309_UP
Drug	salicylate	CRYBA2 TRA2A CRYBB3 SRSF1 ALOX12B ALOX15B	6.30e-05	328	48	6	CID000000338
Drug	isamoxole	ALOX12B ALOX15B	6.49e-05	6	48	2	CID000042118
Drug	fenleuton	LOX ALOX15B	6.49e-05	6	48	2	CID000072059
Drug	1-oleoyl-2-DHA-PC	ALOX12B ALOX15B	6.49e-05	6	48	2	CID006438829
Drug	CPHU	ALOX12B ALOX15B	6.49e-05	6	48	2	CID000124471
Drug	BW A797C	ALOX12B ALOX15B	6.49e-05	6	48	2	CID006439067
Drug	AC1MQ2IQ	LOX ALOX15B	6.49e-05	6	48	2	CID003394960
Drug	tsuwabukinonol	LOX ALOX12B ALOX15B	6.50e-05	37	48	3	CID006440419
Drug	sIL-4R	LOX ALOX12B ALOX15B	6.50e-05	37	48	3	CID000059757
Drug	tricarbon	LOX ALOX12B ALOX15B	7.62e-05	39	48	3	CID006432003
Drug	2-(ethylsulfonyl)ethanol	TRA2A SRSF1 SRSF2 FUT2 TRA2B	7.89e-05	210	48	5	CID000010549
Drug	RvD1	LOX ALOX15B	9.08e-05	7	48	2	CID016061135
Drug	12-IODE	ALOX12B ALOX15B	9.08e-05	7	48	2	CID006450050
Drug	lupenone	ALOX12B ALOX15B	9.08e-05	7	48	2	CID000092158
Drug	dicranin	ALOX12B ALOX15B	9.08e-05	7	48	2	CID006441084
Drug	nimesulide	CACNA1D LOX ALOX12B ALOX15B	9.79e-05	114	48	4	CID000004495
Drug	12-HPETE	LOX ALOX12B ALOX15B	1.02e-04	43	48	3	CID000001415
Drug	BAY X 1005	LOX ALOX12B ALOX15B	1.02e-04	43	48	3	CID000123723
Drug	VML 295	LOX ALOX12B ALOX15B	1.17e-04	45	48	3	CID000177941
Drug	Cgs 22745	ALOX12B ALOX15B	1.21e-04	8	48	2	CID006439321
Drug	htyA	ALOX12B ALOX15B	1.21e-04	8	48	2	CID000152267
Drug	CDNQ	ALOX12B ALOX15B	1.21e-04	8	48	2	CID000126468
Drug	phenidone	LOX ALOX12B ALOX15B	1.25e-04	46	48	3	CID000007090
Drug	hexanal	LOX ALOX12B ALOX15B	1.34e-04	47	48	3	CID000006184
Drug	14,15-leukotriene A4	ALOX12B ALOX15B	1.55e-04	9	48	2	CID006439604
Drug	octadeca-9,12-dien-1-ol	ALOX12B ALOX15B	1.55e-04	9	48	2	CID000068168
Drug	U-56467	ALOX12B ALOX15B	1.55e-04	9	48	2	CID006439532
Drug	8,15-diHPETE	ALOX12B ALOX15B	1.55e-04	9	48	2	CID005283181
Drug	U-66,855	ALOX12B ALOX15B	1.55e-04	9	48	2	CID000127235
Drug	A-78773	ALOX12B ALOX15B	1.55e-04	9	48	2	CID000071460
Drug	quinacrine	CRYBA2 CRYBB3 LTK ALOX12B ALOX15B	1.57e-04	243	48	5	CID000000237
Drug	licofelone	LOX ALOX12B ALOX15B	1.61e-04	50	48	3	CID000133021
Drug	AC1L1C7C	LOX ALOX12B ALOX15B	1.61e-04	50	48	3	CID000001772
Drug	eicosatetraynoic acid	LOX ALOX12B ALOX15B	1.71e-04	51	48	3	CID000135235
Drug	15(S)-HETrE	LOX ALOX15B	1.94e-04	10	48	2	CID000001437
Drug	9-HPODE	ALOX12B ALOX15B	1.94e-04	10	48	2	CID000001928
Drug	1,4-pentadiene	ALOX12B ALOX15B	1.94e-04	10	48	2	CID000011587
Drug	propyl gallate	LOX ALOX12B ALOX15B	2.14e-04	55	48	3	CID000004947
Drug	esculetin	LOX ALOX12B ALOX15B	2.25e-04	56	48	3	CID005281416
Drug	acetone phenylhydrazone	ALOX12B ALOX15B	2.36e-04	11	48	2	CID000066026
Drug	Ity A	ALOX12B ALOX15B	2.36e-04	11	48	2	CID000188274
Drug	AsF3	TRA2A SRSF2	2.36e-04	11	48	2	CID000024571
Drug	BW A137C	ALOX12B ALOX15B	2.36e-04	11	48	2	CID000129265
Drug	17-ODYA	LOX ALOX12B ALOX15B	2.77e-04	60	48	3	CID000001449
Drug	5,8,11-eicosatriynoic acid	LOX ALOX12B ALOX15B	2.77e-04	60	48	3	CID000001781
Drug	zileuton	LOX ALOX12B ALOX15B	2.77e-04	60	48	3	CID000060490
Drug	12-KETE	ALOX12B ALOX15B	2.83e-04	12	48	2	CID005283162
Drug	10(S),17(S)-DiHDoHE	LOX ALOX15B	2.83e-04	12	48	2	CID010089939
Drug	nonenal	ALOX12B ALOX15B	2.83e-04	12	48	2	CID003015503
Drug	3-hydroxyanthranilic acid	NFE2 ALOX12B ALOX15B	2.90e-04	61	48	3	CID000000086
Drug	AA-861	LOX ALOX12B ALOX15B	2.90e-04	61	48	3	CID000001967
Drug	AC1NR1Q2	ALOX12B ALOX15B	3.34e-04	13	48	2	CID005283190
Drug	AC1L1BGZ	ALOX12B ALOX15B	3.34e-04	13	48	2	CID000001435
Drug	9-HETE	ALOX12B ALOX15B	3.34e-04	13	48	2	CID000001926
Drug	hypolaetin	ALOX12B ALOX15B	3.34e-04	13	48	2	CID005281648
Drug	ICI207968	ALOX12B ALOX15B	3.34e-04	13	48	2	CID000129095
Drug	AC1O4E1A	ALOX12B ALOX15B	3.34e-04	13	48	2	CID006365736
Drug	pentosidine	CRYBA2 CRYBB3 LOX	3.35e-04	64	48	3	CID000119593
Drug	ibuprofen	TRA2A SRSF1 LOX ALOX12B ALOX15B	3.77e-04	294	48	5	CID000003672
Drug	AC1NR1LB	ALOX12B ALOX15B	3.90e-04	14	48	2	CID005283131
Drug	timegadine	ALOX12B ALOX15B	3.90e-04	14	48	2	CID000068902
Disease	juvenile polyposis syndrome (implicated_via_orthology)	HIVEP3 HIVEP1 HIVEP2	1.00e-06	13	46	3	DOID:0050787 (implicated_via_orthology)
Disease	CATARACT, ANTERIOR POLAR	CRYBA2 CRYBB3	1.42e-05	4	46	2	C1855179
Disease	lung squamous cell carcinoma (is_marker_for)	SRSF1 SRSF2 DDR2	2.44e-05	36	46	3	DOID:3907 (is_marker_for)
Disease	Progressive supranuclear palsy	SRSF2 TRA2B	3.55e-05	6	46	2	C0038868
Disease	Ophthalmoplegia, Progressive Supranuclear	SRSF2 TRA2B	3.55e-05	6	46	2	C4551862
Disease	Supranuclear Palsy, Progressive, 1	SRSF2 TRA2B	3.55e-05	6	46	2	C4551863
Disease	erythronate measurement	CACNA1D DDR2	4.97e-05	7	46	2	EFO_0021025
Disease	seropositivity measurement	FUT2 HLA-DQB2	8.50e-05	9	46	2	EFO_0007034
Disease	Alzheimer's disease (implicated_via_orthology)	HIVEP3 HIVEP1 HIVEP2	9.78e-05	57	46	3	DOID:10652 (implicated_via_orthology)
Disease	secreted and transmembrane protein 1 measurement	FUT2 HLA-DQB2	1.06e-04	10	46	2	EFO_0021852
Disease	schizophrenia (implicated_via_orthology)	BACE1 CACNA1D HIVEP2	1.66e-04	68	46	3	DOID:5419 (implicated_via_orthology)
Disease	cystatin-D measurement	CA12 FUT2	3.19e-04	17	46	2	EFO_0008103
Disease	Nuclear cataract	CRYBA2 CRYBB3	3.58e-04	18	46	2	C0392557
Disease	noggin measurement	HIVEP2 NFE2	3.58e-04	18	46	2	EFO_0021995
Disease	Nuclear non-senile cataract	CRYBA2 CRYBB3	3.58e-04	18	46	2	C1112705
Disease	urate measurement	CA12 OAS1 FLRT1 CUBN KRT17 HLA-DQB2 DDR2	4.40e-04	895	46	7	EFO_0004531
Disease	treatment-resistant hypertension	CACNA1D HLA-DQB2 DDR2	6.63e-04	109	46	3	EFO_1002006
Disease	Deafness	CACNA1D PISD	6.97e-04	25	46	2	C0011053
Disease	chronic lymphocytic leukemia	PISD HLA-DQB2 SEC23IP	8.55e-04	119	46	3	EFO_0000095
Disease	very low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio	CRYBA2 FUT2 TASOR HLA-DQB2	1.09e-03	291	46	4	EFO_0008317, EFO_0020946
Disease	vitamin B12 measurement	FUT2 CUBN	1.14e-03	32	46	2	EFO_0004620
Disease	lupus nephritis	HIVEP3 HLA-DQB2	1.22e-03	33	46	2	EFO_0005761
Disease	clear cell renal cell carcinoma (is_marker_for)	SRSF1 SRSF2	1.22e-03	33	46	2	DOID:4467 (is_marker_for)

Protein segments in the cluster

Peptide	Gene	Start	Entry
RDQEKYLYRYPGGES	PFKFB2	351	O60825
YRDLRKGVYVPYTQG	BACE1	121	P56817
LGGLGYTRDYPYERI	ACAD9	401	Q9H845
PGYRGYQYVLERDRH	CRYBA2	156	P53672
ERALDYYGLYDDRGR	RBM15B	301	Q8NDT2
YYGYRNPSCEDGRLR	MEPCE	421	Q7L2J0
YSGDYYRIQGRAVLP	DDR2	736	Q16832
GYPANEYAYRRGIAE	FOLH1	271	Q04609
LPERTAEYYRYRGSL	CA12	211	O43570
GRVARFRYFEDIYGY	CPSF1	926	Q10570
VRGVARYIYNREEYG	HLA-DQB2	56	P05538
GMARDIYRASYYRRG	LTK	666	P29376
TDDPRRYQKYGYIGT	OAS1	356	P00973
PRAGRDYSAYYRQIE	KRT20	111	P35900
RRGDRYDDYRDYDSP	RBM5	46	P52756
VEPNGLIRGYRVYYT	PTPRS	451	Q13332
DYLELYDGPRQMGRY	CUBN	1336	O60494
GRPYRDTAAYRYLVK	FMC1	26	Q96HJ9
GPARDYSQYYRTIEE	KRT17	126	Q04695
EYRHIPGEYVRFTGY	FUT2	136	Q10981
YEFPGYRGRQYVFER	CRYBB3	161	P26998
YRGRQYVFERGEYRH	CRYBB3	166	P26998
RGDRTIYDYVRGNYL	AREL1	41	O15033
VERGVQDLPGYYYRD	ALOX12B	486	O75342
YYDTYERPRPGGRYR	LOX	186	P28300
DEGPEGRYRKYAYEP	FIGNL2	271	A6NMB9
RGYRDGGIPDIDYSY	FLRT1	631	Q9NZU1
GYYSRYPGRNIDSER	CACNA1D	1866	Q01668
DRYRDGYRDGYRDGP	EIF4B	231	P23588
YRGGGDRYEDRYDRR	EIF4B	291	P23588
GRRRSEYVEMYPVEY	NFE2	166	Q16621
RTRGVEDIPGYYYRD	ALOX15B	461	O15296
KYGRVGDVYIPRDRY	SRSF2	36	Q01130
GGRYDVYLYDRIRKA	SEC23IP	316	Q9Y6Y8
YLGPRDEGYSSRDGY	RBMXL2	206	O75526
GQRYYGFGRTVYPEE	RSRP1	136	Q9BUV0
YFYEYGFDELRRRPR	TASOR	301	Q9UK61
PVRRRYEPYGMYSDD	CLASP1	811	Q7Z460
DFVPALRDYSRRYYG	RBMXL3	251	Q8N7X1
DRYGEEGCYEEYRGR	RBMXL3	381	Q8N7X1
HYGGEGRYEEYRGRS	RBMXL3	416	Q8N7X1
RYGGEGRYEYRGRSH	RBMXL3	546	Q8N7X1
RQYLRSGPDYDFARY	REX1BD	86	Q96EN9
GYAGYRQYEKYRERE	PISD	76	Q9UG56
GRRRDSYYDRGYDRG	TRA2A	231	Q13595
EEYVYVRGRGRGKYV	HIVEP3	1741	Q5T1R4
GYDYDGYRLRVEFPR	SRSF1	76	Q07955
GDRVGYDYDVCRKPY	HIVEP2	631	P31629
EDYVYVRGRGRGKYI	HIVEP2	1786	P31629
GEPLYRVSTGNYEYR	PICK1	281	Q9NRD5
PTYGSSRRRDYYDRG	TRA2B	211	P62995
SRRRDYYDRGYDRGY	TRA2B	216	P62995
YKSNEEYVYVRGRGR	HIVEP1	2071	P15822
ERDYVRDLGYVVEGY	TRIO	1981	O75962
YRRIYPGPDTEKYAR	TTLL13	476	A6NNM8