Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionsodium channel activity

SCNN1D CACNA1G

1.11e-0352192GO:0005272
GeneOntologyBiologicalProcesspositive regulation of nuclear-transcribed mRNA poly(A) tail shortening

TNRC6B TNRC6C

6.51e-0514182GO:0060213
GeneOntologyBiologicalProcesspositive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

TNRC6B TNRC6C

8.57e-0516182GO:1900153
GeneOntologyBiologicalProcessregulation of nuclear-transcribed mRNA poly(A) tail shortening

TNRC6B TNRC6C

8.57e-0516182GO:0060211
GeneOntologyBiologicalProcessregulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

TNRC6B TNRC6C

2.49e-0427182GO:1900151
GeneOntologyBiologicalProcessnuclear-transcribed mRNA poly(A) tail shortening

TNRC6B TNRC6C

3.74e-0433182GO:0000289
GeneOntologyCellularComponentsodium channel complex

SCNN1D CACNA1G

3.13e-0429192GO:0034706
GeneOntologyCellularComponentmonoatomic ion channel complex

SCNN1D CACNA1G LRRTM4 AKAP9

3.29e-04378194GO:0034702
GeneOntologyCellularComponenttransmembrane transporter complex

SCNN1D CACNA1G LRRTM4 AKAP9

1.11e-03523194GO:1902495
GeneOntologyCellularComponentcation channel complex

SCNN1D CACNA1G AKAP9

1.19e-03235193GO:0034703
GeneOntologyCellularComponenttransporter complex

SCNN1D CACNA1G LRRTM4 AKAP9

1.34e-03550194GO:1990351
DomainAgo_hook

TNRC6B TNRC6C

2.63e-063182PF10427
DomainTNRC6_PABC-bd

TNRC6B TNRC6C

2.63e-063182IPR032226
DomainArgonaute_hook_dom

TNRC6B TNRC6C

2.63e-063182IPR019486
DomainTNRC6-PABC_bdg

TNRC6B TNRC6C

2.63e-063182PF16608
DomainRA

ARHGAP20 PLCE1

5.42e-0436182PF00788
DomainRA

ARHGAP20 PLCE1

5.73e-0437182PS50200
DomainRA_dom

ARHGAP20 PLCE1

6.70e-0440182IPR000159
DomainUBA-like

TNRC6B TNRC6C

1.71e-0364182IPR009060
Domain-

PLEKHA4 ARHGAP20 PLCE1

5.88e-033911832.30.29.30
DomainPH_dom-like

PLEKHA4 ARHGAP20 PLCE1

7.45e-03426183IPR011993
DomainUbiquitin-rel_dom

ARHGAP20 PLCE1

1.33e-02184182IPR029071
DomainRRM

TNRC6B TNRC6C

2.03e-02230182PS50102
PathwayREACTOME_POST_TRANSCRIPTIONAL_SILENCING_BY_SMALL_RNAS

TNRC6B TNRC6C

2.21e-057152M46421
PathwayREACTOME_REGULATION_OF_PTEN_MRNA_TRANSLATION

TNRC6B TNRC6C

3.79e-059152M27810
PathwayREACTOME_REGULATION_OF_NPAS4_MRNA_TRANSLATION

TNRC6B TNRC6C

3.79e-059152M46436
PathwayREACTOME_REGULATION_OF_CDH11_MRNA_TRANSLATION_BY_MICRORNAS

TNRC6B TNRC6C

4.73e-0510152M48013
PathwayREACTOME_REGULATION_OF_NPAS4_GENE_EXPRESSION

TNRC6B TNRC6C

8.19e-0513152M46434
PathwayREACTOME_REGULATION_OF_RUNX1_EXPRESSION_AND_ACTIVITY

TNRC6B TNRC6C

1.42e-0417152M27788
PathwayREACTOME_REGULATION_OF_MITF_M_DEPENDENT_GENES_INVOLVED_IN_APOPTOSIS

TNRC6B TNRC6C

1.79e-0419152M48238
PathwayREACTOME_TGFBR3_EXPRESSION

TNRC6B TNRC6C

3.93e-0428152M48253
PathwayREACTOME_REGULATION_OF_HOMOTYPIC_CELL_CELL_ADHESION

TNRC6B TNRC6C

5.15e-0432152M48012
PathwayREACTOME_REGULATION_OF_MECP2_EXPRESSION_AND_ACTIVITY

TNRC6B TNRC6C

5.15e-0432152M27900
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_NPAS4

TNRC6B TNRC6C

5.81e-0434152M46422
PathwayREACTOME_ONCOGENE_INDUCED_SENESCENCE

TNRC6B TNRC6C

6.16e-0435152M27190
PathwayREACTOME_NR1H3_NR1H2_REGULATE_GENE_EXPRESSION_LINKED_TO_CHOLESTEROL_TRANSPORT_AND_EFFLUX

TNRC6B TNRC6C

6.89e-0437152M29790
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_VENTX

TNRC6B TNRC6C

8.46e-0441152M29748
PathwayREACTOME_NR1H2_AND_NR1H3_MEDIATED_SIGNALING

TNRC6B TNRC6C

1.11e-0347152M29777
PathwayREACTOME_SIGNALING_BY_TGFBR3

TNRC6B TNRC6C

1.21e-0349152M48250
PathwayREACTOME_ADHERENS_JUNCTIONS_INTERACTIONS

TNRC6B TNRC6C

1.69e-0358152M11980
PathwayREACTOME_CA2_PATHWAY

TNRC6B TNRC6C

1.93e-0362152M27321
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_MECP2

TNRC6B TNRC6C

1.99e-0363152M27862
PathwayREACTOME_TP53_REGULATES_METABOLIC_GENES

TNRC6B TNRC6C

3.50e-0384152M27495
PathwayREACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES

EHHADH AKAP9

4.01e-0390152MM14979
PathwayREACTOME_CELL_CELL_JUNCTION_ORGANIZATION

TNRC6B TNRC6C

4.01e-0390152M820
PathwayREACTOME_MAPK6_MAPK4_SIGNALING

TNRC6B TNRC6C

4.28e-0393152M27572
PathwayREACTOME_MITF_M_DEPENDENT_GENE_EXPRESSION

TNRC6B TNRC6C

4.46e-0395152M48268
PathwayREACTOME_RUNX1_REGULATES_GENES_INVOLVED_IN_MEGAKARYOCYTE_DIFFERENTIATION_AND_PLATELET_FUNCTION

TNRC6B TNRC6C

4.55e-0396152M27792
Pubmed

Gawky is a component of cytoplasmic mRNA processing bodies required for early Drosophila development.

TNRC6B TNRC6C

8.48e-07319216880270
Pubmed

Impact of scaffolding protein TNRC6 paralogs on gene expression and splicing.

TNRC6B TNRC6C

8.48e-07319234108231
Pubmed

Expression of TNRC6 (GW182) Proteins Is Not Necessary for Gene Silencing by Fully Complementary RNA Duplexes.

TNRC6B TNRC6C

8.48e-07319231670606
Pubmed

Two PABPC1-binding sites in GW182 proteins promote miRNA-mediated gene silencing.

TNRC6B TNRC6C

1.70e-06419221063388
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

TNRC6B TNRC6C PLCE1 PHF8 AKAP9

2.18e-0640719512693553
Pubmed

Ago-TNRC6 triggers microRNA-mediated decay by promoting two deadenylation steps.

TNRC6B TNRC6C

2.82e-06519219838187
Pubmed

The C-terminal domains of human TNRC6A, TNRC6B, and TNRC6C silence bound transcripts independently of Argonaute proteins.

TNRC6B TNRC6C

5.93e-06719219383768
Pubmed

Functional dissection of the human TNRC6 (GW182-related) family of proteins.

TNRC6B TNRC6C

5.93e-06719219470757
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

TNRC6B CACNA1G TNRC6C PHF8

6.13e-0622519412168954
Pubmed

Mammalian miRNA RISC recruits CAF1 and PABP to affect PABP-dependent deadenylation.

TNRC6B TNRC6C

2.56e-051419219716330
Pubmed

GW182 proteins directly recruit cytoplasmic deadenylase complexes to miRNA targets.

TNRC6B TNRC6C

2.96e-051519221981923
Pubmed

QKI is a critical pre-mRNA alternative splicing regulator of cardiac myofibrillogenesis and contractile function.

CACNA1G AKAP9

5.34e-052019233397958
Pubmed

Trinucleotide repeat containing 6a (Tnrc6a)-mediated microRNA function is required for development of yolk sac endoderm.

TNRC6B TNRC6C

6.49e-052219222187428
Pubmed

Trinucleotide repeat containing 6c (TNRC6c) is essential for microvascular maturation during distal airspace sacculation in the developing lung.

TNRC6B TNRC6C

7.10e-052319228811219
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

ARHGAP20 TMEM131L CACNA1G PDPR

1.71e-0452919414621295
Pubmed

Genome-wide association study of the rate of cognitive decline in Alzheimer's disease.

ARHGAP20 CACNA1G

3.83e-045319223535033
CytobandEnsembl 112 genes in cytogenetic band chr10q23

OPN4 PLCE1

2.93e-03195192chr10q23
GeneFamilyAtaxins|Trinucleotide repeat containing

TNRC6B TNRC6C

1.00e-0425112775
ToppCellfacs-Large_Intestine-Proximal-3m|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP20 EHHADH DMBT1

5.17e-0517319399532bb768ee35fed939a377acb5215d3f8904bd
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP20 EHHADH DMBT1

5.17e-05173193e1378201b15ffb98e196ac39fe3ee4b4078953bd
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-nan|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP20 EHHADH DMBT1

5.45e-051761931dd54bfaa58541de51e5a8328651d390833bd480
ToppCellLPS-IL1RA+antiTNF|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARHGAP20 TNRC6B TMEM131L

5.54e-05177193b7fee75de7e96924af488a5baa2334711889ae7c
ToppCellfacs-Skin-nan-18m-Mesenchymal-nan|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP20 CACNA1G LRRTM4

6.73e-0518919329287525120be2953b76881ba3cfc4379c265e7a
ToppCellfacs-Skin-nan-18m-Mesenchymal-fibroblast|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP20 CACNA1G LRRTM4

6.73e-051891937150dad9a92a715487c2d8130fa01b752ea69663
ToppCellfacs-Skin-nan-18m-Mesenchymal|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP20 CACNA1G LRRTM4

6.73e-051891936e4c0effd5192fd00052abc048fdb87a74fb6554
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_VISp_Col6a1_Fezf2|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PLEKHA4 CRYBA2

1.58e-04441922aa44b57544d5264db5b265ae60f7460c5b2a217
ToppCellEntopeduncular-Macroglia-OLIGODENDROCYTE-O1-Trf|Entopeduncular / BrainAtlas - Mouse McCarroll V32

OPN4 CCDC78

4.73e-0476192efbbbf91bca35720d8ecddb076f2c9f4de25e44d
ToppCellEntopeduncular-Macroglia-OLIGODENDROCYTE-O1|Entopeduncular / BrainAtlas - Mouse McCarroll V32

OPN4 CCDC78

4.73e-0476192254d18bece2676faa4bbeb8d48b1d327ab3c2215
ToppCellTCGA-Testes-Primary_Tumor-Testicular_Germ_Cell_Tumor-Testicular_Germ_Cell_Tumor-4|TCGA-Testes / Sample_Type by Project: Shred V9

OPN4 DMBT1

1.02e-031121923ec029eac64247c5e48074dad5c71df690e84f4c
ToppCell3'_v3-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8|bone_marrow / Manually curated celltypes from each tissue

TNRC6B AKAP9

1.19e-0312119219333a660800b583fa27b495c1f7828e6636a257
ToppCellTCGA-Adrenal-Primary_Tumor-Pheochromocytoma-Pheochromocytoma-5|TCGA-Adrenal / Sample_Type by Project: Shred V9

CRYBA2 TNRC6C

1.46e-03134192d4b175257c47916ed90cdb5c555c2b26530ce8d5
ToppCell3'_v3-blood-Lymphocytic_T_CD4-T_CD4/CD8|blood / Manually curated celltypes from each tissue

TNRC6B AKAP9

1.48e-03135192ae2d3a42e567b5bade304c0caa497eb725be3565
ToppCelldroplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Mesenchymal-fibroblast|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLEKHA4 PLCE1

1.54e-03138192e2659949944bdf39b23c7275e380a7a937e2726c
ToppCelldroplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLEKHA4 PLCE1

1.54e-03138192d5342383c5e52b92c39d7afe76560501be3ea5cd
ToppCellNasal_Brush-Epithelial-Club|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

DMBT1 PHF8

1.82e-03150192c68645ffcffe524cf1d9736cf72a15b37ed8dc3d
ToppCellNasal_Brush-Epithelial-Club|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

DMBT1 PHF8

1.82e-03150192d39d73a1de6a873292d48e469d9403f513045be3
ToppCellmild_COVID-19_(asymptomatic)-NK_CD56bright|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)

EHHADH CCDC78

1.84e-031511922470162f4b56bc505db166a6eb0fa54847759df8
ToppCellTCGA-Thymus-Primary_Tumor-Thymoma-Type_AB-8|TCGA-Thymus / Sample_Type by Project: Shred V9

ARHGAP20 PLCE1

1.84e-031511925906562efd36fbcb91f96e0a0d3a8fe999ba1e79
ToppCellmild_COVID-19_(asymptomatic)-NK_CD56bright|World / disease group, cell group and cell class (v2)

EHHADH CCDC78

1.89e-03153192aff5c8ab1fb4ebc324cec02cf562b7484bb10db8
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Neural|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LRRTM4 PLCE1

1.92e-0315419242bd8f88fd075a2d4edde394785decad88a2660a
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Neural-neural_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LRRTM4 PLCE1

1.92e-031541926425d9861148586466febd6eceae1b1f9b9a14c1
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Neural-neural_cell-Schwann_Cell_/_Neural-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LRRTM4 PLCE1

1.92e-0315419230cb4bb297fa815adb829f3b5cafca56fcbcb810
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Neural-neural_cell-Schwann_Cell_/_Neural|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LRRTM4 PLCE1

1.92e-03154192ade094e2947761a0a34daa8fcff3e9ea8437e4a5
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Lect1_Oxtr|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

DMBT1 PLCE1

1.94e-0315519299e749f7075e2c64e9a0bf91009f95b6969197c8
ToppCellPND07-28-samps-Mesenchymal-Mesothelial-Mesothelial|PND07-28-samps / Age Group, Lineage, Cell class and subclass

CACNA1G PLCE1

1.97e-03156192605d95a900e1443d3f6aae163ef2e893d3293203
ToppCellPND07-28-samps-Mesenchymal-Mesothelial|PND07-28-samps / Age Group, Lineage, Cell class and subclass

CACNA1G PLCE1

1.97e-03156192574f761962a7dd3308bd41fc529dd3ea1b8625f8
ToppCell5'-Adult-Appendix-Hematopoietic-T_cells-CD8_Tmem|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CACNA1G LRRTM4

2.01e-03158192da060f5b61c7088f700d138b02ea596adacf7d60
ToppCellBac-SEP-Lymphocyte-T_NK-NK_CD56bright|Bac-SEP / Disease, Lineage and Cell Type

PLEKHA4 CCDC78

2.01e-0315819220411158d71699a80f6c1566791af89dea0e1875
ToppCellBasal_cells-Donor_06|World / lung cells shred on cell class, cell subclass, sample id

PLEKHA4 PLCE1

2.01e-03158192dd069a822e9698e6dddc155d9a5b52383f7879d5
ToppCellfacs-Marrow-Granulocytes-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLEKHA4 CACNA1G

2.07e-0316019256e6f4b82b5dc41c45f9d253c2db314a6f702b84
ToppCellfacs-Marrow-Granulocytes-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLEKHA4 CACNA1G

2.07e-03160192bb1b966fb9e801db15e67d03e49db4609d6f935a
ToppCellE15.5-Mesenchymal-mesenchymal_fibroblast-tracheal_fibroblast|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CACNA1G PHF8

2.09e-031611929703b7e67d9fadb6129cad166bd01be915042e44
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Neural-neural_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LRRTM4 PLCE1

2.12e-03162192d28b2ea1d2c8f3c6a107991573471b6d0c49c4ae
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Neural-neural_cell-Schwann_Cell_/_Neural-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LRRTM4 PLCE1

2.12e-031621925bbd7130d4dad9035e73a439dda568195c136f31
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Neural-neural_cell-Schwann_Cell_/_Neural|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LRRTM4 PLCE1

2.12e-03162192eed223e61c8162a2fe004ab4e09de5e037be7553
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Neural|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LRRTM4 PLCE1

2.12e-03162192e35ddce830e20ebeac1a2c405293fc4a5323dd4a
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-immature_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1G PDPR

2.12e-03162192966df4558140c3d541999ab553f201ae76a1c401
ToppCell10x5'-blood-Lymphocytic_T_CD4-T_CD4/CD8|blood / Manually curated celltypes from each tissue

TNRC6B TMEM131L

2.12e-03162192b4535bcb3f469bc139e73f1122f4070013e5a1de
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-immature_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1G PDPR

2.12e-0316219222f1abd20f43bc7e7fc46969da9962faf70ae5d2
ToppCellfacs-Pancreas-Endocrine-24m-Epithelial-pancreatic_PP_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLEKHA4 LRRTM4

2.17e-0316419274a35ba77e93d864161beb6b133d654473981bb7
ToppCelldroplet-Lung-nan-3m-Myeloid-Ccr7+_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCDC78 PLCE1

2.17e-0316419278de403446fe0eb375c82ff1832cc5fbb8e20afa
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_B_(ET)-Glut_ET_L5_FEZF2-Exc_L5_FEZF2_SCN7A|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CRYBA2 OPN4

2.19e-031651922a1401929b950275e86d1f36d7d1eaf84b85c469
ToppCellCOVID-CD8-exh_CD4|COVID / Condition, Cell_class and T cell subcluster

TMEM131L PHF8

2.22e-031661924ca8c91b03d08489f244898cf9423b9d10348bc8
ToppCell343B-Lymphocytic-ILC|343B / Donor, Lineage, Cell class and subclass (all cells)

SCNN1D PHF8

2.22e-03166192a54377c703efff42d2cc1a8fdb610facc58053dd
ToppCell3'-Child04-06-SmallIntestine-Epithelial-neuro-epithelial-L_cells_(PYY+)|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PLEKHA4 CRYBA2

2.25e-031671925accd0bc7c95089feb2c09376d12cd8bd3773775
ToppCell15-Distal-Epithelial-Multiciliated_precursor|Distal / Age, Tissue, Lineage and Cell class

TP53AIP1 CCDC78

2.25e-03167192442ea71a581ed5a547a214132b9f1b0243fd0895
ToppCelltumor_Lymph_Node_/_Brain-T/NK_cells-CD8+/CD4+_Mixed_Th|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

SCNN1D TMEM131L

2.25e-03167192c0c944eae0514dc8e00d0c2892a0792e157695ec
ToppCellChildren_(3_yrs)-Mesenchymal-chondrocyte-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

ARHGAP20 SCNN1D

2.25e-03167192f4943fb5001475ddab82a0273bcbb3fa68fdd7bd
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L6_LHX6_GLP1R|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

OPN4 PLCE1

2.27e-031681922eed7dc1a2aff11be024823c4323c42bc94362f6
ToppCellControl-B_cells-Activated_B_cells|Control / group, cell type (main and fine annotations)

TNRC6B TMEM131L

2.27e-03168192a7159a35fe37f8c241cf8d391debe271e0698105
ToppCellfacs-Large_Intestine-Proximal|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP20 DMBT1

2.27e-0316819223e0e1592d7400012d289adb10c7598285bae2e9
ToppCellLA-16._Neuronal|World / Chamber and Cluster_Paper

LRRTM4 PLCE1

2.27e-031681922fd1fd2a16ac1c5eb028f93cc3a2477c7747693e
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW23-OPC_related|GW23 / Sample Type, Dataset, Time_group, and Cell type.

SCNN1D PLCE1

2.30e-0316919229db25e7c5f31d98a08a35d7ec5ade203242bc50
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW23-OPC_related-Oligodendrocyte/OPC|GW23 / Sample Type, Dataset, Time_group, and Cell type.

SCNN1D PLCE1

2.30e-03169192b1611e61f635f8f9b87250e026ad30999cbee041
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L6_LHX6_GLP1R|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

OPN4 PLCE1

2.33e-0317019240675b55269ffa57fb7fcdb903c81b02b4e01f8f
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Ptprt_Pkp2|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

LRRTM4 PLCE1

2.33e-0317019214aa86a4f526ed6986afcb28c49225522055550c
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-hematologic-erythrocytic-erythroid_lineage_cell|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

TP53AIP1 CRYBA2

2.33e-03170192288014dedda8babc51fe08e48a55e68d83e1b1d2
ToppCell5'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial-L_cells_(PYY+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CRYBA2 HHLA1

2.33e-031701926a98f47f8c2b5b15e09169bd82eff1e6bf76e5a6
ToppCell10x3'2.3-week_12-13-Myeloid_DC-DC-DC1|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

ARHGAP20 SCNN1D

2.35e-0317119204346d4eb726875e3537e215ea081a0318ca4ddd
ToppCellfacs-Heart-LV-3m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM131L CCDC78

2.35e-0317119255b194a9bf4d3e4b5d96e0d1298424359c441cbb
ToppCell368C-Myeloid-Macrophage-FABP4+_Macrophage_2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

SCNN1D PLCE1

2.35e-03171192e59afa0a773dca3b9c208d17510ea55703b42598
ToppCellfacs-Heart-LV-3m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM131L CCDC78

2.35e-03171192c6fc9ef9735dbf5314a4c7dac2b2954b0985ae4d
ToppCell3'_v3-lymph-node_spleen|World / Manually curated celltypes from each tissue

TNRC6B TNRC6C

2.35e-031711927aae88da5b37c20f10118325a048f08906be994c
ToppCelltumor_Lymph_Node_/_Brain-T/NK_cells-CD8+/CD4+_Mixed_Th|T/NK_cells / Location, Cell class and cell subclass

SCNN1D TMEM131L

2.41e-0317319242c911ed16fabdabef063830e8407192d8bde950
ToppCellAdult-Mesenchymal-pericyte_cell-D175|Adult / Lineage, Cell type, age group and donor

LRRTM4 PLCE1

2.41e-03173192fd6653d6be9ca6ac36798590694efe03cb758c67
ToppCell5'-GW_trimst-1.5-LargeIntestine-Neuronal-Glial_immature-Glia_1_(DHH+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PLEKHA4 LRRTM4

2.41e-03173192789ab8b2709f4b8728e3733bc72744e9d92ea5ea
ToppCell5'-GW_trimst-2-LymphNode-Neuronal-Glial_immature-Glia_1_(DHH+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PLEKHA4 LRRTM4

2.44e-031741921463c98f8f519dd030587abbdbeb1b4e1bca5dd1
ToppCell5'-GW_trimst-2-LymphNode-Neuronal-Glial_immature|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PLEKHA4 LRRTM4

2.44e-03174192c9d4e375dedd2b099a9ed70ec38ff35bbb0ce48a
ToppCell5'-GW_trimst-2-LymphNode-Neuronal|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PLEKHA4 LRRTM4

2.44e-03174192d421c0069d24cb560a3a429929e3cd1eceaeabcf
ToppCellfacs-Heart-LV-24m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1G PLCE1

2.44e-03174192197686570cec6d96a92e77e6409325d3bfe6f991
ToppCellPCW_10-12-Epithelial-Epithelial_ciliated-epi_ciliated_(14)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

TP53AIP1 CCDC78

2.44e-0317419200cf27bc23af1472a507be31fba6245a8fdd901b
ToppCellPCW_10-12-Epithelial-Epithelial_ciliated|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

TP53AIP1 CCDC78

2.44e-03174192b8d1c556290d188f56aeefc17f03119686945fe7
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_FAM150B|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

OPN4 PLCE1

2.44e-03174192cc4c7f00a25a7814b52d4599166615daa140cc31
ToppCellfacs-Heart-LV-24m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1G PLCE1

2.44e-031741922eee7b5471672b439f95eba11494c2adf8cb7006
ToppCellmetastatic_Brain-Endothelial_cells-Stalk-like_ECs|Endothelial_cells / Location, Cell class and cell subclass

ARHGAP20 EHHADH

2.46e-03175192f6a6db992e803d36c866a91706b02f67e0fd3e09
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TMEM131L PLCE1

2.46e-03175192d52794426f2703a80e91ae0a8ff2d8e0ce4aa4a8
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TMEM131L PLCE1

2.46e-03175192454f03e6109d65f5db08dbb41ecc19ffb6bbc4e0
ToppCellPCW_13-14-Epithelial-Epithelial_ciliated-epi_ciliated_(14)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

TP53AIP1 CCDC78

2.46e-03175192c82ec6deb6ccdd991a69a62b6d62d5b14c803d7a
ToppCellPCW_13-14-Epithelial-Epithelial_ciliated|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

TP53AIP1 CCDC78

2.46e-03175192b1369d2b74f461e6822d0c33e9b50fe0dfbceb54
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CRYBA2 CCDC78

2.49e-03176192dee780cfa85234a7cd7bf440b66b84cec959893e
ToppCell390C-Fibroblasts-Fibroblast-B_(Myofibroblast)|390C / Donor, Lineage, Cell class and subclass (all cells)

PLEKHA4 CACNA1G

2.49e-03176192852d3da0907fe87c0ef23d75a63ce07619cf0c54
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HHLA1 OPN4

2.49e-03176192fcf324e6402819683f95e0dd94bf1f777c7f4c76
ToppCellP15-Epithelial-epithelial_progenitor_cell-epithelial_unknown_3|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

PLEKHA4 PLCE1

2.49e-03176192792f414f5092aba14260b8e16378e793a822498e
ToppCell390C-Fibroblasts-Fibroblast-B_(Myofibroblast)-|390C / Donor, Lineage, Cell class and subclass (all cells)

PLEKHA4 CACNA1G

2.49e-03176192d2df1e435996c51213e88270af9f928e9e09a6f5
ToppCell368C-Epithelial_cells-Epithelial-B_(AT2)-|368C / Donor, Lineage, Cell class and subclass (all cells)

HHLA1 DMBT1

2.52e-03177192ac8f774596068e66c0a9ea8a318be0ce5f5df834
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TMEM131L PLCE1

2.52e-03177192a8625d14682183cf77cb51eaf11bc15a3528f586
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TMEM131L PLCE1

2.52e-031771923645e2f4a48283f290f85c49c3e79e3f58ac9aa6
ToppCell5'-GW_trimst-1.5-SmallIntestine-Epithelial-neuro-epithelial-EECs|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CRYBA2 DMBT1

2.52e-031771925bccc7a74019eae8afd977a9c9134d884857ac27
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L6_LHX6_GLP1R|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

OPN4 PLCE1

2.52e-031771922b675840b7d2bb536c2c600936733bd9e97e7120
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L6_LHX6_GLP1R|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

OPN4 PLCE1

2.52e-031771925e0fca9bd5e5ffe6d39f5bcd81f36512f3b0cb1b
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

OPN4 CCDC78

2.52e-03177192aef050784abbba45c4ab4e8328339c8739c5c453
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP20 LRRTM4

2.52e-031771929ec7f1e64312d26d434b3312b58386715dbad644
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP20 LRRTM4

2.52e-03177192016277dfd59b1793fddaaadc2b3f41622d76ce3a
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma|TCGA-Brain / Sample_Type by Project: Shred V9

TNRC6B TNRC6C

2.52e-03177192e8ab340b20cd41554c3841fe980e078e878af35f
ToppCell368C-Epithelial_cells-Epithelial-B_(AT2)|368C / Donor, Lineage, Cell class and subclass (all cells)

HHLA1 DMBT1

2.52e-03177192d9c4a93b0e04a13bf39992dd1c1ec8df2c5f89fe
ToppCellChildren_(3_yrs)-Mesenchymal-pericyte_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

LRRTM4 PLCE1

2.55e-03178192185b44700f06ec58b3c09c80520502166c965fd6
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

TNRC6B EHHADH

2.55e-0317819273936c2e7e8855b4ab65cad425686513dba331a3
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLEKHA4 CCDC78

2.55e-03178192f02076ece0fa899e620971c887ad4da7f48684ed
Diseaseesophageal squamous cell carcinoma

HHLA1 PLCE1

3.05e-0513192EFO_0005922
Diseaselactate measurement

ARHGAP20 PDPR

2.87e-0439192EFO_0007745
Diseaseascending aortic diameter

TNRC6B PLCE1

3.63e-03140192EFO_0021787
Diseasecircadian rhythm

TNRC6B AKAP9

4.88e-03163192EFO_0004354
Diseaseperipheral arterial disease, traffic air pollution measurement

OPN4 LRRTM4

6.83e-03194192EFO_0004265, EFO_0007908

Protein segments in the cluster

PeptideGeneStartEntry
EPTTWSLTSDRTRNW

AKAP9

3466

Q99996
PRWSAWSGSSSHNSN

CRYBA2

76

P53672
IRSISQGLTWTWSSL

LRRTM4

241

Q86VH4
WSTPSGASWKTASAR

EHHADH

281

Q08426
SPGWQNWSSARNSTS

PDPR

16

Q8NCN5
PSWWDSSQSSISSLG

OPN4

26

Q9UHM6
PWSAASSWTSRRSSR

CACNA1G

1096

O43497
LSYRSTWTSTWAGTS

CCDC78

421

A2IDD5
WWHPTTTTTARPSSN

DMBT1

1751

Q9UGM3
SRWPSAKSAGWTLAT

SCNN1D

631

P51172
SGSLPWERASASSWT

ARHGAP20

1151

Q9P2F6
QSTPWASALRSSPWT

HHLA1

256

C9JL84
GSAWSTDTSGRTSSW

TNRC6C

1501

Q9HCJ0
SSGSWSSATVWILTG

TP53AIP1

71

Q9HCN2
RASRGSWGSWSSTSS

TMEM131L

1316

A2VDJ0
KSPSSAWSSSSWHGR

PLCE1

1181

Q9P212
SGAQKWLRSSGSWSS

PLEKHA4

641

Q9H4M7
WLRSSGSWSSPRNTT

PLEKHA4

646

Q9H4M7
SSSPATSSLQAWWTG

PHF8

771

Q9UPP1
SSPWSSTAPRSVRGW

TNRC6B

1611

Q9UPQ9