Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionDNA-binding transcription factor activity, RNA polymerase II-specific

ZNF711 ZNF419 ZNF384 ZNF134 ZBTB46 ZNF594 ZSCAN5B ZNF610 ZNF845 ZNF777 ZNF573 ZNF394 WIZ ZFP3 ZNF556 ZNF175 ZNF253 ZNF184 ZNF641 ZSCAN26 ZNF316 ZNF347 ZBTB21 OSR2 ZNF778 ZNF808 ZNF616 INSM2 ZNF880 ZBTB41 ZNF397 MYNN ZNF528 ZNF396 ZNF225 ZNF227 ZNF850 PRDM15 ZFX ZFY ZNF461 ZNF546 ZNF705G ZNF44

1.73e-3014127844GO:0000981
GeneOntologyMolecularFunctionRNA polymerase II transcription regulatory region sequence-specific DNA binding

ZNF711 ZNF419 ZNF384 ZNF134 ZNF594 ZSCAN5B ZNF610 ZNF845 ZNF777 ZNF573 ZNF394 WIZ ZFP3 ZNF556 ZNF175 ZNF253 ZNF184 ZNF641 ZSCAN26 ZNF316 ZNF347 OSR2 ZNF778 ZNF808 ZNF616 INSM2 ZNF880 ZBTB41 ZNF397 MYNN ZNF528 ZNF396 ZNF225 ZNF227 ZNF850 PRDM15 ZFX ZFY ZNF461 ZNF546 ZNF705G ZNF44

1.76e-2714597842GO:0000977
GeneOntologyMolecularFunctionRNA polymerase II cis-regulatory region sequence-specific DNA binding

ZNF711 ZNF419 ZNF384 ZNF134 ZNF594 ZSCAN5B ZNF610 ZNF845 ZNF573 ZNF394 WIZ ZFP3 ZNF175 ZNF253 ZNF184 ZSCAN26 ZNF316 ZNF347 ZNF778 ZNF808 ZNF616 INSM2 ZNF880 ZBTB41 ZNF397 MYNN ZNF528 ZNF396 ZNF225 ZNF227 ZNF850 PRDM15 ZFX ZFY ZNF461 ZNF546

4.17e-2312447836GO:0000978
GeneOntologyMolecularFunctioncis-regulatory region sequence-specific DNA binding

ZNF711 ZNF419 ZNF384 ZNF134 ZNF594 ZSCAN5B ZNF610 ZNF845 ZNF573 ZNF394 WIZ ZFP3 ZNF175 ZNF253 ZNF184 ZSCAN26 ZNF316 ZNF347 ZNF778 ZNF808 ZNF616 INSM2 ZNF880 ZBTB41 ZNF397 MYNN ZNF528 ZNF396 ZNF225 ZNF227 ZNF850 PRDM15 ZFX ZFY ZNF461 ZNF546

8.61e-2312717836GO:0000987
GeneOntologyMolecularFunctionDNA-binding transcription activator activity, RNA polymerase II-specific

ZNF384 ZNF594 ZNF845 ZNF175 OSR2 ZNF778 ZNF808 ZNF225 ZNF227 ZNF850 PRDM15 ZFX ZFY

2.40e-075607813GO:0001228
GeneOntologyMolecularFunctionDNA-binding transcription activator activity

ZNF384 ZNF594 ZNF845 ZNF175 OSR2 ZNF778 ZNF808 ZNF225 ZNF227 ZNF850 PRDM15 ZFX ZFY

2.71e-075667813GO:0001216
GeneOntologyMolecularFunctionchromatin insulator sequence binding

REPIN1 ZFX ZFY

1.98e-067783GO:0043035
GeneOntologyMolecularFunctionDNA-binding transcription repressor activity, RNA polymerase II-specific

ZNF134 ZBTB46 ZFP3 ZNF175 ZBTB21 INSM2 MYNN

2.54e-04320787GO:0001227
GeneOntologyMolecularFunctionDNA-binding transcription repressor activity

ZNF134 ZBTB46 ZFP3 ZNF175 ZBTB21 INSM2 MYNN

2.84e-04326787GO:0001217
GeneOntologyMolecularFunctionclathrin light chain binding

NSG2 CLTC

3.12e-047782GO:0032051
GeneOntologyMolecularFunctionstore-operated calcium channel activity

TRPC7 TRPC6

9.69e-0412782GO:0015279
GeneOntologyMolecularFunctioninositol 1,4,5 trisphosphate binding

TRPC7 TRPC6

1.33e-0314782GO:0070679
GeneOntologyMolecularFunctionclathrin binding

NSG2 TRPC6 CLTC

1.92e-0363783GO:0030276
GeneOntologyMolecularFunctiontransmembrane receptor protein tyrosine kinase activator activity

HBEGF NRG3

3.31e-0322782GO:0030297
GeneOntologyBiologicalProcesspositive regulation of transcription by RNA polymerase II

ZNF711 ZNF384 ZNF594 ZNF845 ZC3H12A ZNF175 SMARCA1 OSR2 ZNF808 ZNF225 ZNF227 ACVR2A ZNF850 PRDM15 ZFX ZFY

3.80e-0513907616GO:0045944
Domain-

ZNF711 ZNF419 ZNF384 ZNF134 ZBTB46 ZNF594 ZSCAN5B ZNF610 ZNF845 ZNF777 ZNF573 ZNF394 ZFP3 ZNF556 ZNF175 ZNF253 ZNF184 ZNF641 ZSCAN26 ZNF316 ZNF347 ZBTB21 OSR2 ZNF778 ZNF808 ZNF616 INSM2 ZNF880 ZBTB41 ZNF397 MYNN ZNF528 ZNF396 ZNF225 ZNF227 ZNF850 PRDM15 REPIN1 ZFX ZFY ZNF461 ZNF546 ZNF705G ZNF44

5.33e-4367978443.30.160.60
DomainZnf_C2H2/integrase_DNA-bd

ZNF711 ZNF419 ZNF384 ZNF134 ZBTB46 ZNF594 ZSCAN5B ZNF610 ZNF845 ZNF777 ZNF573 ZNF394 ZFP3 ZNF556 ZNF175 ZNF253 ZNF184 ZNF641 ZSCAN26 ZNF316 ZNF347 ZBTB21 OSR2 ZNF778 ZNF808 ZNF616 INSM2 ZNF880 ZBTB41 ZNF397 MYNN ZNF528 ZNF396 ZNF225 ZNF227 ZNF850 PRDM15 REPIN1 ZFX ZFY ZNF461 ZNF546 ZNF705G ZNF44

1.40e-426947844IPR013087
DomainZINC_FINGER_C2H2_2

ZNF711 ZNF419 ZNF384 ZNF134 ZBTB46 ZNF594 ZSCAN5B ZNF610 ZNF845 ZNF777 ZNF573 ZNF394 WIZ ZFP3 ZNF556 ZNF175 ZNF253 ZNF184 ZNF641 ZSCAN26 ZNF316 ZNF347 ZBTB21 OSR2 ZNF778 ZNF808 ZNF616 INSM2 ZNF880 ZBTB41 ZNF397 MYNN ZNF528 ZNF396 ZNF225 ZNF227 ZNF850 PRDM15 REPIN1 ZFX ZFY ZNF461 ZNF546 ZNF705G ZNF44

5.55e-427757845PS50157
DomainZINC_FINGER_C2H2_1

ZNF711 ZNF419 ZNF384 ZNF134 ZBTB46 ZNF594 ZSCAN5B ZNF610 ZNF845 ZNF777 ZNF573 ZNF394 WIZ ZFP3 ZNF556 ZNF175 ZNF253 ZNF184 ZNF641 ZSCAN26 ZNF316 ZNF347 ZBTB21 OSR2 ZNF778 ZNF808 ZNF616 INSM2 ZNF880 ZBTB41 ZNF397 MYNN ZNF528 ZNF396 ZNF225 ZNF227 ZNF850 PRDM15 REPIN1 ZFX ZFY ZNF461 ZNF546 ZNF705G ZNF44

6.23e-427777845PS00028
DomainZnf_C2H2-like

ZNF711 ZNF419 ZNF384 ZNF134 ZBTB46 ZNF594 ZSCAN5B ZNF610 ZNF845 ZNF777 ZNF573 ZNF394 WIZ ZFP3 ZNF556 ZNF175 ZNF253 ZNF184 ZNF641 ZSCAN26 ZNF316 ZNF347 ZBTB21 OSR2 ZNF778 ZNF808 ZNF616 INSM2 ZNF880 ZBTB41 ZNF397 MYNN ZNF528 ZNF396 ZNF225 ZNF227 ZNF850 PRDM15 REPIN1 ZFX ZFY ZNF461 ZNF546 ZNF705G ZNF44

1.84e-417967845IPR015880
DomainZnf_C2H2

ZNF711 ZNF419 ZNF384 ZNF134 ZBTB46 ZNF594 ZSCAN5B ZNF610 ZNF845 ZNF777 ZNF573 ZNF394 WIZ ZFP3 ZNF556 ZNF175 ZNF253 ZNF184 ZNF641 ZSCAN26 ZNF316 ZNF347 ZBTB21 OSR2 ZNF778 ZNF808 ZNF616 INSM2 ZNF880 ZBTB41 ZNF397 MYNN ZNF528 ZNF396 ZNF225 ZNF227 ZNF850 PRDM15 REPIN1 ZFX ZFY ZNF461 ZNF546 ZNF705G ZNF44

3.05e-418057845IPR007087
DomainZnF_C2H2

ZNF711 ZNF419 ZNF384 ZNF134 ZBTB46 ZNF594 ZSCAN5B ZNF610 ZNF845 ZNF777 ZNF573 ZNF394 WIZ ZFP3 ZNF556 ZNF175 ZNF253 ZNF184 ZNF641 ZSCAN26 ZNF316 ZNF347 ZBTB21 OSR2 ZNF778 ZNF808 ZNF616 INSM2 ZNF880 ZBTB41 ZNF397 MYNN ZNF528 ZNF396 ZNF225 ZNF227 ZNF850 PRDM15 REPIN1 ZFX ZFY ZNF461 ZNF546 ZNF705G ZNF44

3.60e-418087845SM00355
Domainzf-C2H2

ZNF711 ZNF419 ZNF384 ZNF134 ZBTB46 ZNF594 ZSCAN5B ZNF610 ZNF845 ZNF777 ZNF573 ZNF394 ZFP3 ZNF556 ZNF175 ZNF253 ZNF184 ZNF641 ZSCAN26 ZNF316 ZNF347 ZBTB21 OSR2 ZNF778 ZNF808 ZNF616 INSM2 ZNF880 ZBTB41 ZNF397 MYNN ZNF528 ZNF396 ZNF225 ZNF227 ZNF850 PRDM15 REPIN1 ZFX ZFY ZNF461 ZNF546 ZNF44

4.57e-416937843PF00096
DomainKRAB

ZNF419 ZNF610 ZNF845 ZNF777 ZNF573 ZNF394 ZNF556 ZNF175 ZNF253 ZNF184 ZNF641 ZNF316 ZNF347 ZNF778 ZNF808 ZNF616 ZNF880 ZNF528 ZNF225 ZNF227 ZNF850 ZNF461 ZNF546 ZNF705G ZNF44

3.41e-243587825PS50805
DomainKRAB

ZNF419 ZNF610 ZNF845 ZNF777 ZNF573 ZNF394 ZNF556 ZNF175 ZNF253 ZNF184 ZNF641 ZNF316 ZNF347 ZNF778 ZNF808 ZNF616 ZNF880 ZNF528 ZNF225 ZNF227 ZNF850 ZNF461 ZNF546 ZNF705G ZNF44

3.41e-243587825PF01352
DomainKRAB

ZNF419 ZNF610 ZNF845 ZNF777 ZNF573 ZNF394 ZNF556 ZNF175 ZNF253 ZNF184 ZNF641 ZNF316 ZNF347 ZNF778 ZNF808 ZNF616 ZNF880 ZNF528 ZNF225 ZNF227 ZNF850 ZNF461 ZNF546 ZNF705G ZNF44

7.23e-243697825SM00349
DomainKRAB

ZNF419 ZNF610 ZNF845 ZNF777 ZNF573 ZNF394 ZNF556 ZNF175 ZNF253 ZNF184 ZNF641 ZNF316 ZNF347 ZNF778 ZNF808 ZNF616 ZNF880 ZNF528 ZNF225 ZNF227 ZNF850 ZNF461 ZNF546 ZNF705G ZNF44

7.73e-243707825IPR001909
Domainzf-C2H2_6

ZNF419 ZNF384 ZSCAN5B ZNF845 ZNF573 ZNF556 ZNF253 ZNF184 ZNF316 OSR2 ZNF778 ZNF808 ZNF616 ZNF880 ZBTB41 MYNN ZNF225 ZNF227 ZNF850 ZNF461 ZNF546 ZNF44

2.67e-213147822PF13912
DomainTranscrp_activ_Zfx/Zfy-dom

ZNF711 ZFX ZFY

7.01e-083783IPR006794
DomainZfx_Zfy_act

ZNF711 ZFX ZFY

7.01e-083783PF04704
DomainSCAN

ZSCAN5B ZNF394 ZSCAN26 ZNF397 ZNF396

3.61e-0656785SM00431
DomainSCAN_BOX

ZSCAN5B ZNF394 ZSCAN26 ZNF397 ZNF396

4.30e-0658785PS50804
DomainSCAN

ZSCAN5B ZNF394 ZSCAN26 ZNF397 ZNF396

4.30e-0658785PF02023
DomainSCAN_dom

ZSCAN5B ZNF394 ZSCAN26 ZNF397 ZNF396

4.30e-0658785IPR003309
DomainRetrov_capsid_C

ZSCAN5B ZNF394 ZSCAN26 ZNF397 ZNF396

4.68e-0659785IPR008916
DomainZF_C3H1

CPSF4L ZC3H12A MBNL1 MBNL3

1.01e-0458784PS50103
DomainTRP_dom

TRPC7 TRPC6

2.55e-046782IPR013555
DomainTRP_2

TRPC7 TRPC6

2.55e-046782PF08344
DomainTRPC_channel

TRPC7 TRPC6

3.57e-047782IPR002153
Domain-

CPSF4L MBNL1 MBNL3

6.19e-04407834.10.1000.10
DomainTRP_channel

TRPC7 TRPC6

9.24e-0411782IPR004729
DomainZnF_C3H1

CPSF4L MBNL1 MBNL3

1.06e-0348783SM00356
Domainzf-CCCH

CPSF4L MBNL1 MBNL3

1.12e-0349783PF00642
DomainZnf_CCCH

CPSF4L MBNL1 MBNL3

1.83e-0358783IPR000571
DomainLAMININ_NTER

LAMC1 USH2A

1.99e-0316782PS51117
DomainLaminin_N

LAMC1 USH2A

1.99e-0316782PF00055
DomainLaminin_N

LAMC1 USH2A

1.99e-0316782IPR008211
DomainLamNT

LAMC1 USH2A

1.99e-0316782SM00136
DomainBTB

ZBTB46 ZBTB21 ZBTB41 MYNN

2.21e-03131784PF00651
DomainC2H2_Znf_fam

ZSCAN5B ZNF641

4.48e-0324782IPR027775
DomainBTB

ZBTB46 ZBTB21 ZBTB41 MYNN

4.53e-03160784PS50097
DomainBTB

ZBTB46 ZBTB21 ZBTB41 MYNN

6.84e-03180784SM00225
DomainEGF_LAM_2

LAMC1 USH2A

6.94e-0330782PS50027
DomainEGF_LAM_1

LAMC1 USH2A

6.94e-0330782PS01248
DomainBTB/POZ_dom

ZBTB46 ZBTB21 ZBTB41 MYNN

7.52e-03185784IPR000210
DomainSKP1/BTB/POZ

ZBTB46 ZBTB21 ZBTB41 MYNN

8.10e-03189784IPR011333
DomainLaminin_EGF

LAMC1 USH2A

9.37e-0335782PF00053
DomainEGF_Lam

LAMC1 USH2A

9.37e-0335782SM00180
DomainLaminin_EGF

LAMC1 USH2A

1.10e-0238782IPR002049
DomainDEAH_ATP_HELICASE

DHX37 SMARCA1

1.10e-0238782PS00690
PathwayREACTOME_RNA_POLYMERASE_II_TRANSCRIPTION

ZNF711 ZNF419 ZNF610 ZNF777 ZNF573 ZNF394 ZNF556 ZNF175 ZNF253 ZNF184 ZNF641 ZNF347 ZNF778 ZNF616 ZNF528 ZNF225 ZNF227 ZNF461 ZNF546 ZNF705G

1.65e-0813875020M734
PathwayREACTOME_GENERIC_TRANSCRIPTION_PATHWAY

ZNF711 ZNF419 ZNF610 ZNF845 ZNF394 ZNF184 ZNF641 ZNF347 ZNF778 ZNF808 ZNF616 ZNF850 ZNF44

1.83e-067685013MM14851
PathwayREACTOME_GENE_EXPRESSION_TRANSCRIPTION

ZNF711 ZNF419 ZNF610 ZNF845 ZNF394 ZNF184 ZNF641 ZNF347 ZNF778 ZNF808 ZNF616 ZNF850 ZNF44

4.02e-0510225013MM15436
PathwayREACTOME_PI3K_EVENTS_IN_ERBB4_SIGNALING

HBEGF NRG3

3.41e-048502MM14532
PathwayREACTOME_PI3K_EVENTS_IN_ERBB4_SIGNALING

HBEGF NRG3

5.45e-0410502M568
PathwayREACTOME_ROLE_OF_SECOND_MESSENGERS_IN_NETRIN_1_SIGNALING

TRPC7 TRPC6

5.45e-0410502M27330
PathwayREACTOME_ERBB2_ACTIVATES_PTK6_SIGNALING

HBEGF NRG3

6.64e-0411502MM15478
PathwayREACTOME_GRB2_EVENTS_IN_ERBB2_SIGNALING

HBEGF NRG3

6.64e-0411502MM14760
PathwayREACTOME_SHC1_EVENTS_IN_ERBB4_SIGNALING

HBEGF NRG3

6.64e-0411502MM14533
PathwayREACTOME_ERBB2_ACTIVATES_PTK6_SIGNALING

HBEGF NRG3

9.38e-0413502M27729
PathwayREACTOME_ERBB2_REGULATES_CELL_MOTILITY

HBEGF NRG3

9.38e-0413502MM15320
PathwayREACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS

TRPC7 TRPC6

9.38e-0413502MM14553
PathwayREACTOME_REGULATION_OF_ENDOGENOUS_RETROELEMENTS

ZNF610 ZNF347 ZNF616

1.02e-0356503MM17236
PathwayREACTOME_SHC1_EVENTS_IN_ERBB4_SIGNALING

HBEGF NRG3

1.09e-0314502M569
PathwayREACTOME_PI3K_EVENTS_IN_ERBB2_SIGNALING

HBEGF NRG3

1.09e-0314502MM14761
PathwayREACTOME_SHC1_EVENTS_IN_ERBB2_SIGNALING

HBEGF NRG3

1.09e-0314502MM14531
PathwayPID_ERBB_NETWORK_PATHWAY

HBEGF NRG3

1.26e-0315502M201
PathwayREACTOME_ERBB2_REGULATES_CELL_MOTILITY

HBEGF NRG3

1.26e-0315502M27608
PathwayREACTOME_GRB2_EVENTS_IN_ERBB2_SIGNALING

HBEGF NRG3

1.43e-0316502M562
PathwayREACTOME_PI3K_EVENTS_IN_ERBB2_SIGNALING

HBEGF NRG3

1.43e-0316502M570
PathwayREACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS

TRPC7 TRPC6

1.43e-0316502M26945
PathwayWP_PROTEOGLYCAN_BIOSYNTHESIS

EXTL3 CHST3

1.82e-0318502M39865
PathwayREACTOME_SHC1_EVENTS_IN_ERBB2_SIGNALING

HBEGF NRG3

2.72e-0322502M26929
Pubmed

Rapid and efficient cloning of cDNAs encoding Krüppel-like zinc finger proteins by degenerate PCR.

ZNF610 ZNF175 ZNF347 ZNF778 ZNF616 MYNN ZNF850

1.72e-11497879630514
Pubmed

Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.

ZNF419 ZBTB46 ZSCAN5B ZNF610 TES ZNF394 WIZ ZNF175 MBNL1 ZNF347 ZBTB21 ZNF616 ZBTB41 ZNF397 MYNN MBNL3

2.80e-11808781620412781
Pubmed

Acetylation-Mimic Mutation of TRIM28-Lys304 to Gln Attenuates the Interaction with KRAB-Zinc-Finger Proteins and Affects Gene Expression in Leukemic K562 Cells.

ZNF419 ZNF845 ZNF253 ZNF184 ZNF316 ZNF778 ZNF227 ZNF44

7.92e-0918178837372979
Pubmed

Characterization of the ZFX family of transcription factors that bind downstream of the start site of CpG island promoters.

ZNF711 ZFX ZFY

1.09e-08378332406922
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

ZNF711 ZNF384 ZNF845 WIZ DHX37 MORF4L1 ZNF184 ZSCAN26 ZBTB21 SMARCA1 PRDM15

1.15e-07608781136089195
Pubmed

Characterization of the mid-foregut transcriptome identifies genes regulated during lung bud induction.

ZNF610 ZNF347 ZNF778 ZNF616 ZNF850

2.47e-076078518023262
Pubmed

Identification of differentially expressed genes in mouse spermatogenesis.

ZNF610 MYO7B ZNF347 ZNF616

3.95e-072778414581517
Pubmed

The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.

ZNF711 ZNF384 ZNF845 MORF4L1 CANX ZNF184 CLTC ZSCAN26 ZNF316 LAMC1 ZNF808 ZNF227 ZNF850 REPIN1

4.22e-071203781429180619
Pubmed

Zinc finger protein genes in the mouse genome.

ZFP3 ZFX ZFY

2.35e-06127831797234
Pubmed

An atlas of combinatorial transcriptional regulation in mouse and man.

ZNF384 ZNF556 ZNF175 ZNF184 ZNF641 SMARCA1 INSM2 ZNF397 MYNN ZNF396 ZFY

4.11e-06877781120211142
Pubmed

Differential rates of evolution for the ZFY-related zinc finger genes, Zfy, Zfx, and Zfa in the mouse genus Mus.

ZFX ZFY

4.97e-06278212716983
Pubmed

Intron/exon structure confirms that mouse Zfy1 and Zfy2 are members of the ZFY gene family.

ZFX ZFY

4.97e-0627829126493
Pubmed

Transcription factor Zfx controls BCR-induced proliferation and survival of B lymphocytes.

ZFX ZFY

4.97e-06278219329779
Pubmed

Chromosomal localization of ZFX--a human gene that escapes X inactivation--and its murine homologs.

ZFX ZFY

4.97e-0627821970799
Pubmed

Evolution of the Zfx and Zfy genes: rates and interdependence between the genes.

ZFX ZFY

4.97e-0627828487630
Pubmed

Zfa is an expressed retroposon derived from an alternative transcript of the Zfx gene.

ZFX ZFY

4.97e-0627821691708
Pubmed

The structure of the Zfx gene on the mouse X chromosome.

ZFX ZFY

4.97e-0627828188262
Pubmed

Comparison of human ZFY and ZFX transcripts.

ZFX ZFY

4.97e-0627822308929
Pubmed

Mapping the human ZFX locus to Xp21.3 by in situ hybridization.

ZFX ZFY

4.97e-0627822497060
Pubmed

RNAi as a tool to control the sex ratio of mouse offspring by interrupting Zfx/Zfy genes in the testis.

ZFX ZFY

4.97e-06278228251288
Pubmed

Comparison of ZFY and ZFX gene structure and analysis of alternative 3' untranslated regions of ZFY.

ZFX ZFY

4.97e-0627822041734
Pubmed

Molecular determinants for cardiovascular TRPC6 channel regulation by Ca2+/calmodulin-dependent kinase II.

TRPC7 TRPC6

4.97e-06278223529130
Pubmed

Gene expression, X-inactivation, and methylation during spermatogenesis: the case of Zfa, Zfx, and Zfy in mice.

ZFX ZFY

4.97e-0627828318216
Pubmed

Mouse Zfx protein is similar to Zfy-2: each contains an acidic activating domain and 13 zinc fingers.

ZFX ZFY

4.97e-0627822105457
Pubmed

Recruitment of human muscleblind proteins to (CUG)(n) expansions associated with myotonic dystrophy.

MBNL1 MBNL3

4.97e-06278210970838
Pubmed

Circ_0000520 contributes to triple-negative breast cancer progression through mediating the miR-1296/ZFX axis.

ZFX ZFY

4.97e-06278234324278
Pubmed

Zfx mutation results in small animal size and reduced germ cell number in male and female mice.

ZFX ZFY

4.97e-0627829187153
Pubmed

[Expression of Zfx in mouse testicular spermatogenic cells].

ZFX ZFY

4.97e-06278238602753
Pubmed

Regional assignments of the zinc finger Y-linked gene (ZFY) and related sequences on human and mouse chromosomes.

ZFX ZFY

4.97e-0627822265557
Pubmed

PLC-mediated PI(4,5)P2 hydrolysis regulates activation and inactivation of TRPC6/7 channels.

TRPC7 TRPC6

4.97e-06278224470487
Pubmed

ZBTB20 is crucial for the specification of a subset of callosal projection neurons and astrocytes in the mammalian neocortex.

ZBTB46 ZBTB21 ZBTB41 MYNN

1.26e-056378434351428
Pubmed

Isolation of cDNA clones for 42 different Krüppel-related zinc finger proteins expressed in the human monoblast cell line U-937.

ZNF594 ZNF227 ZNF461

1.40e-05217837865130
Pubmed

Muscleblind-like proteins: similarities and differences in normal and myotonic dystrophy muscle.

MBNL1 MBNL3

1.49e-05378219095965
Pubmed

Loss of MBNL1 induces RNA misprocessing in the thymus and peripheral blood.

MBNL1 MBNL3

1.49e-05378232332745
Pubmed

Zfy gene expression patterns are not compatible with a primary role in mouse sex determination.

ZFX ZFY

1.49e-0537822480529
Pubmed

Three proteins, MBNL, MBLL and MBXL, co-localize in vivo with nuclear foci of expanded-repeat transcripts in DM1 and DM2 cells.

MBNL1 MBNL3

1.49e-05378211929853
Pubmed

Muscleblind proteins regulate alternative splicing.

MBNL1 MBNL3

1.49e-05378215257297
Pubmed

Disrupted prenatal RNA processing and myogenesis in congenital myotonic dystrophy.

MBNL1 MBNL3

1.49e-05378228698297
Pubmed

Genetic dissection of mammalian fertility pathways.

ZFX ZFY

1.49e-05378212479614
Pubmed

Isolation of monochromosomal hybrids for mouse chromosomes 3, 6, 10, 12, 14, and 18.

ZFX ZFY

1.49e-0537829060403
Pubmed

Blockade of ZFX Alleviates Hypoxia-Induced Pulmonary Vascular Remodeling by Regulating the YAP Signaling.

ZFX ZFY

1.49e-05378238310188
Pubmed

Loss of MBNL leads to disruption of developmentally regulated alternative polyadenylation in RNA-mediated disease.

MBNL1 MBNL3

1.49e-05378225263597
Pubmed

ZNF384 Fusion Oncoproteins Drive Lineage Aberrancy in Acute Leukemia.

ZNF384 ZNF394

1.49e-05378235247902
Pubmed

YAC clone contigs surrounding the Zfx and Pola loci on the mouse X chromosome.

ZFX ZFY

1.49e-0537828406471
Pubmed

The Retinal Basis of Light Aversion in Neonatal Mice.

TRPC7 TRPC6

1.49e-05378235396331
Pubmed

X chromosome genes and premature ovarian failure.

ZFX ZFY

1.49e-05378211299520
Pubmed

Major contribution of the 3/6/7 class of TRPC channels to myocardial ischemia/reperfusion and cellular hypoxia/reoxygenation injuries.

TRPC7 TRPC6

1.49e-05378228526717
Pubmed

Clustering of C2-H2 zinc finger motif sequences within telomeric and fragile site regions of human chromosomes.

ZNF397 ZNF546 ZNF44

1.62e-05227831505991
Pubmed

Muscleblind-Like 1 and Muscleblind-Like 3 Depletion Synergistically Enhances Myotonia by Altering Clc-1 RNA Translation.

MBNL1 MBNL3

2.97e-05478226501102
Pubmed

Melanopsin Phototransduction Is Repurposed by ipRGC Subtypes to Shape the Function of Distinct Visual Circuits.

TRPC7 TRPC6

2.97e-05478230017393
Pubmed

ZFX controls propagation and prevents differentiation of acute T-lymphoblastic and myeloid leukemia.

ZFX ZFY

2.97e-05478224485662
Pubmed

Developmental expression of mouse muscleblind genes Mbnl1, Mbnl2 and Mbnl3.

MBNL1 MBNL3

2.97e-05478212915312
Pubmed

Identification and characterization of two novel human SCAN domain-containing zinc finger genes ZNF396 and ZNF397.

ZNF397 ZNF396

2.97e-05478212801647
Pubmed

Zfx controls the self-renewal of embryonic and hematopoietic stem cells.

ZFX ZFY

2.97e-05478217448993
Pubmed

Gene knockouts that cause female infertility: search for novel contraceptive targets.

ACVR2A ZFX ZFY

3.41e-052878315970507
Pubmed

The human gene ZFP161 on 18p11.21-pter encodes a putative c-myc repressor and is homologous to murine Zfp161 (Chr 17) and Zfp161-rs1 (X Chr).

ZFX ZFY

4.94e-0557829244432
Pubmed

Zfx facilitates tumorigenesis caused by activation of the Hedgehog pathway.

ZFX ZFY

4.94e-05578225164012
Pubmed

TRPC channels are necessary mediators of pathologic cardiac hypertrophy.

TRPC7 TRPC6

4.94e-05578220351294
Pubmed

Chromosome mapping and expression of a putative testis-determining gene in mouse.

ZFX ZFY

4.94e-0557822563174
Pubmed

MSG1 (melanocyte-specific gene 1): mapping to chromosome Xq13.1, genomic organization, and promoter analysis.

ZFX ZFY

4.94e-0557829721210
Pubmed

Maintenance of X inactivation of the Rps4, Zfx, and Ube1 genes in a mouse in vitro system.

ZFX ZFY

4.94e-0557827681608
Pubmed

Intrinsic phototransduction persists in melanopsin-expressing ganglion cells lacking diacylglycerol-sensitive TRPC subunits.

TRPC7 TRPC6

4.94e-05578221261756
Pubmed

HAUSP regulates c-MYC expression via de-ubiquitination of TRRAP.

ZNF594 ZNF394 MYNN

6.18e-053478325925205
Pubmed

Sequence and expression of murine cDNAs encoding Xlr3a and Xlr3b, defining a new X-linked lymphocyte-regulated Xlr gene subfamily.

ZFX ZFY

7.40e-0567827821804
Pubmed

MBNL and CELF proteins regulate alternative splicing of the skeletal muscle chloride channel CLCN1.

MBNL1 MBNL3

7.40e-05678219720736
Pubmed

Ts65Dn -- localization of the translocation breakpoint and trisomic gene content in a mouse model for Down syndrome.

ZBTB21 PRDM15

1.04e-04778211528125
Pubmed

MxA, a member of the dynamin superfamily, interacts with the ankyrin-like repeat domain of TRPC.

TRPC7 TRPC6

1.04e-04778215757897
Pubmed

An evaluation of the inactive mouse X chromosome in somatic cell hybrids.

ZFX ZFY

1.04e-0477828460399
Pubmed

Characterization of cDNAs encoding the murine interleukin 2 receptor (IL-2R) gamma chain: chromosomal mapping and tissue specificity of IL-2R gamma chain expression.

ZFX ZFY

1.04e-0477828378320
Pubmed

Embryonic growth and the evolution of the mammalian Y chromosome. II. Suppression of selfish Y-linked growth factors may explain escape from X-inactivation and rapid evolution of Sry.

ZFX ZFY

1.04e-0477827928394
Pubmed

TRPC absence induces pro-inflammatory macrophage polarization to promote obesity and exacerbate colorectal cancer.

TRPC7 TRPC6

1.04e-04778238835669
Pubmed

Progressive impairment of muscle regeneration in muscleblind-like 3 isoform knockout mice.

MBNL1 MBNL3

1.04e-04778223660517
Pubmed

Genome-wide survey and expression profiling of CCCH-zinc finger family reveals a functional module in macrophage activation.

ZC3H12A MBNL3

1.04e-04778218682727
Pubmed

The Dazh gene is expressed in male and female embryonic gonads before germ cell sex differentiation.

ZFX ZFY

1.04e-0477829588208
Pubmed

Coexistence within one cell of microvillous and ciliary phototransductions across M1- through M6-IpRGCs.

TRPC7 TRPC6

1.04e-04778238109525
Pubmed

RNA-seq analysis reveals TRPC genes to impact an unexpected number of metabolic and regulatory pathways.

TRPC7 TRPC6

1.04e-04778232350291
Pubmed

Genetic mapping in the mouse of Kif4, a gene encoding a kinesin-like motor protein.

ZFX ZFY

1.04e-0477829196009
Pubmed

Specific and ubiquitous expression of different Zn finger protein genes in the mouse.

ZNF778 ZNF850

1.04e-0477823143103
Pubmed

TRPC absence induces pro-inflammatory macrophages and gut microbe disorder, sensitizing mice to colitis.

TRPC7 TRPC6

1.04e-04778236592529
Pubmed

Functional role of TRPC proteins in vivo: lessons from TRPC-deficient mouse models.

TRPC7 TRPC6

1.04e-04778215336983
Pubmed

Subunit composition, molecular environment, and activation of native TRPC channels encoded by their interactomes.

TRPC7 TRPC6

1.04e-04778236257322
Pubmed

Conservation of position and exclusive expression of mouse Xist from the inactive X chromosome.

ZFX ZFY

1.38e-0487822034279
Pubmed

Subunit composition of mammalian transient receptor potential channels in living cells.

TRPC7 TRPC6

1.38e-04878212032305
Pubmed

Genetic mapping in the region of the mouse X-inactivation center.

ZFX ZFY

1.38e-0487821974879
Pubmed

Association of immunophilins with mammalian TRPC channels.

TRPC7 TRPC6

1.38e-04878215199065
Pubmed

High-density molecular map of the central span of the mouse X chromosome.

ZFX ZFY

1.38e-0487821675191
Pubmed

Metabolism regulates the spontaneous firing of substantia nigra pars reticulata neurons via KATP and nonselective cation channels.

TRPC7 TRPC6

1.38e-04878225471572
Pubmed

exma: an X-linked insertional mutation that disrupts forebrain and eye development.

ZFX ZFY

1.77e-04978211956759
Pubmed

Structure, chromosomal location, and expression pattern of three mouse genes homologous to the human MAGE genes.

ZFX ZFY

1.77e-0497827590750
Pubmed

Cloning and characterization of a new human Xq13 gene, encoding a putative helicase.

ZFX ZFY

1.77e-0497827874112
Pubmed

The mouse genes encoding the third pair of beta-type proteasome subunits regulated reciprocally by IFN-gamma: structural comparison, chromosomal localization, and analysis of the promoter.

ZFX ZFY

1.77e-0497829300697
Pubmed

Identification of common binding sites for calmodulin and inositol 1,4,5-trisphosphate receptors on the carboxyl termini of trp channels.

TRPC7 TRPC6

1.77e-04978211290752
Pubmed

Praja1, a novel gene encoding a RING-H2 motif in mouse development.

ZFX ZFY

1.77e-0497829393880
Pubmed

Cellular subtype distribution and developmental regulation of TRPC channel members in the mouse dorsal root ganglion.

TRPC7 TRPC6

1.77e-04978217480026
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

ZNF711 ZNF610 TES WIZ MORF4L1 ZNF316 ZBTB21 SMARCA1 REPIN1 ZNF461

1.94e-041116781031753913
Pubmed

Genetic and molecular evidence of an X-chromosome deletion spanning the tabby (Ta) and testicular feminization (Tfm) loci in the mouse.

ZFX ZFY

2.21e-04107822055107
Pubmed

Heterogeneous distribution of TRPC proteins in the embryonic cortex.

TRPC7 TRPC6

2.21e-041078218989690
Pubmed

ErbB/HER ligands in human breast cancer, and relationships with their receptors, the bio-pathological features and prognosis.

HBEGF NRG3

2.21e-041078217962208
Pubmed

The leak channel NALCN controls tonic firing and glycolytic sensitivity of substantia nigra pars reticulata neurons.

TRPC7 TRPC6

2.21e-041078227177420
Pubmed

Mapping of the phosphorylase kinase alpha subunit gene on the mouse X chromosome.

ZFX ZFY

2.21e-04107821973380
InteractionNOTCH2 interactions

ZNF419 ZNF594 ZNF777 ZNF253 ZSCAN26 ZNF316 ZBTB21 ZNF397 MYNN REPIN1

4.67e-064237710int:NOTCH2
InteractionGLI4 interactions

ZNF845 ZNF777 ZNF184 ZNF316 ZNF397 PRDM15

8.35e-06125776int:GLI4
InteractionLTBP2 interactions

ZNF594 ZNF777 ZNF316 ZNF778 REPIN1

1.84e-0585775int:LTBP2
InteractionZBTB47 interactions

ZNF777 ZNF394 ZNF184 ZNF616 PRDM15 REPIN1

1.87e-05144776int:ZBTB47
InteractionZSCAN32 interactions

TES ZNF394 ZNF397 ZNF396

2.61e-0545774int:ZSCAN32
CytobandEnsembl 112 genes in cytogenetic band chr19q13

ZNF419 IGFL1 ZNF134 ZSCAN5B ZNF610 ZNF845 ZNF573 ZNF175 ZNF347 ZNF808 ZNF616 ZNF880 ZNF528 ZNF225 ZNF227 ZNF850 ZNF461 ZNF546

1.24e-1211927818chr19q13
Cytoband19q13.41

ZNF610 ZNF808 ZNF616 ZNF880

9.99e-067878419q13.41
Cytoband19q13.12

ZNF573 ZNF850 ZNF461

2.59e-047278319q13.12
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF711 ZNF419 ZNF384 ZNF134 ZBTB46 ZNF594 ZSCAN5B ZNF610 ZNF845 ZNF777 ZNF573 ZNF394 WIZ ZFP3 ZNF556 ZNF175 ZNF253 ZNF184 ZNF641 ZSCAN26 ZNF316 ZNF347 ZBTB21 OSR2 ZNF778 ZNF808 ZNF616 INSM2 ZNF880 ZBTB41 ZNF397 MYNN ZNF528 ZNF396 ZNF225 ZNF227 ZNF850 PRDM15 REPIN1 ZFX ZFY ZNF461 ZNF546 ZNF705G ZNF44

7.88e-47718684528
GeneFamilyZinc fingers CCCH-type

ZC3H12A MBNL1 MBNL3

3.06e-043568373
GeneFamilyBasic leucine zipper proteins|BTB domain containing

ZBTB46 ZBTB21 ZBTB41 MYNN

1.63e-03134684861
GeneFamilyTransient receptor potential cation channels

TRPC7 TRPC6

4.95e-0328682249
Drugvinylene

ZNF394 ZNF175 ZSCAN26 OSR2 PRDM15 ZFX ZFY ZNF461

1.78e-06245778CID000006326
Diseasemyotonic disease (implicated_via_orthology)

MBNL1 MBNL3

1.71e-053712DOID:450 (implicated_via_orthology)
Diseasemyotonic dystrophy type 2 (implicated_via_orthology)

MBNL1 MBNL3

5.68e-055712DOID:0050759 (implicated_via_orthology)
Diseasemyotonic dystrophy type 1 (implicated_via_orthology)

MBNL1 MBNL3

8.51e-056712DOID:11722 (implicated_via_orthology)
Diseasenicotine dependence (implicated_via_orthology)

TRPC7 TRPC6

3.71e-0412712DOID:0050742 (implicated_via_orthology)
Diseaselung adenocarcinoma

MORF4L1 TRPC6 RASSF3 MYNN

8.34e-04174714EFO_0000571
Diseasecolorectal cancer

TRPC6 MBNL1 LAMC1 MYNN NRG3 CHST3

3.34e-03604716MONDO_0005575

Protein segments in the cluster

PeptideGeneStartEntry
FCKDGPLCKYRHVPR

CPSF4L

131

A6NMK7
GVEPCYGDKDKRRHC

ACVR2A

46

P27037
ESPAKFALYKRCHRE

RASSF3

136

Q86WH2
RVLCFHGPLLYEAKC

MORF4L1

16

Q9UBU8
HFKPCRDKDLAYCLN

NRG3

286

P56975
PGHYHADKKRCRKCA

PCSK5

676

Q92824
CPEGFVYKHKRCIPA

NSG2

101

Q9Y328
ARKHSGEKPYVCDRC

MYNN

406

Q9NPC7
RKKRSGRHRFDPFCC

INSL4

111

Q14641
DERPYTCDICHKAFR

OSR2

196

Q8N2R0
RGSEIFVCPYCHKKF

INSM2

421

Q96T92
CVCGYPRQHVRKYKG

FAM126A

211

Q9BYI3
PKATRGCRLHNCFDY

EXTL3

171

O43909
LCQPHKRCGDKFYDP

IGFL1

36

Q6UW32
PDKCGEDYKLHFIFR

CANX

191

P27824
KGRCSREKCKYFHPP

MBNL1

226

Q9NR56
KGRCSREKCKYFHPP

MBNL3

221

Q9NUK0
LRCYFVLEPKRHGCS

CDH26

636

Q8IXH8
CPACYRLVKDKVADH

LAMC1

1031

P11047
DPCLRKYKDFCIHGE

HBEGF

106

Q99075
DYSGECFRKVCKIHR

DHX37

451

Q8IY37
EKLCAGIPRDEHCFY

PCDH11Y

126

Q9BZA8
KPGHRCCEEKYIPFV

USH2A

3201

O75445
KLYCGRHYCDSEKPR

TES

286

Q9UGI8
LRKCCNHPYLFDGAE

SMARCA1

456

P28370
GIKEYECKECHRRFA

PRDM15

1136

P57071
VKARDKYRHPECFVC

PDLIM3

306

Q53GG5
LKHEERKCPYCPDRF

WIZ

696

O95785
EYRPVKVRGCFDHSK

SURF1

116

Q15526
CPDCGKAFRHKPYLA

REPIN1

461

Q9BWE0
GKYCEKRDPHLACVA

CLTC

906

Q00610
VFEKYHCKNRRCGPL

CHST3

241

Q7LGC8
RYLACHRRCHTGKKP

ZNF845

256

Q96IR2
PYKCNECGRAFHKRP

ZNF610

371

Q8N9Z0
PEKPYACDICHKRFH

ZBTB21

571

Q9ULJ3
RPYKCAHPGCEKAFT

ZNF384

371

Q8TF68
KPYRCHECGKDFTRN

ZNF880

546

Q6PDB4
GEKPYKCLECGERFR

ZNF394

521

Q53GI3
REKPFACVVCGKYFR

ZNF778

361

Q96MU6
KPYKCDVCGKAFRHR

ZNF616

351

Q08AN1
KCTYGIKCRFFHPER

ZC3H12A

311

Q5D1E8
PYICEKCGKAFRRGH

ZNF573

301

Q86YE8
ADRFYRGILEPDKHC

SLITRK5

851

O94991
IEDIKHRRYYEKPCC

MRPS21

36

P82921
RIHTGERPFKCKYCS

ZSCAN5B

431

A6NJL1
KRYECDECGKTFIRH

ZBTB41

601

Q5SVQ8
GRPYECKHCGKAFRC

ZNF556

256

Q9HAH1
RPYECKECGKAFRLH

ZNF546

271

Q86UE3
ERPYECKECGKAFRL

ZNF546

326

Q86UE3
HGKCPFRSFCFRRKA

UNC5CL

336

Q8IV45
CHRRCHTGEKPYKCK

ZNF808

276

Q8N4W9
GERPYACHLCRKAFT

ZNF705G

196

A8MUZ8
KRCTDHNCEPYKRLF

ZPBP

246

Q9BS86
PYKCHECGKVFRRNS

ZNF347

456

Q96SE7
KPYRCEECGKGYKRR

ZNF225

426

Q9UK10
KPYLCIHCGKNFRRS

ZSCAN26

336

Q16670
KPYRCRECGKAFNHS

ZNF253

366

O75346
FPCPDCGKRFVYKSH

ZNF316

401

A6NFI3
EERPYRCDVCGHSFK

ZNF397

281

Q8NF99
HRCEYCKKGFRRPSE

ZFX

776

P17010
ERPYRCSKCGKAFRG

ZNF528

546

Q3MIS6
PYKCDICDKDFRHRS

ZNF227

771

Q86WZ6
KPYECHRCGKTFSGR

ZNF594

321

Q96JF6
KGARIERPHDYFCKC

TRPC6

241

Q9Y210
RIHSGKKPYACDECA

ZNF396

271

Q96N95
YPHRCEFCKKGFRRP

ZNF711

731

Q9Y462
RPYHCAECGKRFTQK

ZNF777

776

Q9ULD5
KPYECRECGKFFRHN

ZNF419

481

Q96HQ0
RPYECKHCGKAFSRS

ZNF44

606

P15621
PYDCKECGKAFRLRL

ZNF850

616

A8MQ14
PYDCKECGKAFRRRS

ZNF850

896

A8MQ14
RPYKCSDCGKVFRHK

ZNF134

286

P52741
YPCEICGKKFTRREH

ZBTB46

446

Q86UZ6
AKPYECAECGKAFRH

ZNF184

611

Q99676
PYECKECGKTFRHRS

ZNF461

356

Q8TAF7
RERPFVCYKCGKAFV

ZNF175

611

Q9Y473
PHRCEYCKKGFRRPS

ZFY

771

P08048
KGARIERPHDYFCKC

TRPC7

186

Q9HCX4
KPYECFECGKAFRRT

ZFP3

391

Q96NJ6
PYSCLKCEKTFGRRH

ZNF641

291

Q96N77
LPKYLRGFHKCSRED

MYO7B

1916

Q6PIF6