EPHB4 CDK17 EPHA6 PSKH1 SPEG SRC MAP3K4 JAK3 KSR1 NEK1 GRK2 GRK3 BRAF PKM FGR ALK DDR1 CAMK1D ADCK5 KSR2 LCK CASK EGFR MTOR PRKAA1 PRKAA2 PRKCD PRKCI MAPK6 MAP3K21 PSKH2 HCK NEK11 EPHA7 EPHB1

EPHB4 CDK17 EPHA6 PSKH1 SPEG SRC MAP3K4 JAK3 KSR1 NEK1 GRK2 GRK3 BRAF SPHK1 PKM XYLB FGR ALK DDR1 CAMK1D ADCK5 KSR2 LCK CASK EGFR MTOR PRKAA1 PRKAA2 NT5C2 PRKCD PRKCI MAPK6 MAP3K21 PSKH2 HCK NEK11 EPHA7 EPHB1

EPHB4 PRPSAP1 PRPSAP2 CDK17 NMNAT2 EPHA6 PSKH1 SPEG SRC MAP3K4 JAK3 KSR1 NEK1 GRK2 GRK3 BRAF SPHK1 PKM XYLB FGR ALK DDR1 CAMK1D ADCK5 POLG KSR2 LCK CASK POLR3B EGFR MTOR GYS2 PRKAA1 PRKAA2 NT5C2 PRKCD PRKCI MAPK6 MAP3K21 PSKH2 HCK NEK11 EPHA7 EPHB1

EPHB4 CDK17 EPHA6 PSKH1 SPEG SRC MAP3K4 JAK3 KSR1 NEK1 GRK2 GRK3 BRAF SPHK1 PKM XYLB FGR ALK DDR1 CAMK1D ADCK5 KSR2 LCK CASK EGFR MTOR PRKAA1 PRKAA2 NT5C2 PRKCD PRKCI MAPK6 MAP3K21 PSKH2 HCK NEK11 EPHA7 EPHB1

EPHB4 EPHA6 SRC JAK3 NEK1 PKM FGR ALK DDR1 LCK EGFR PRKCD HCK EPHA7 EPHB1

ABCA2 CCT3 MYO5B PSMC5 CHD3 BCS1L ABCB4 MDN1 DDX23 DDX60L ABCD1 DNAH8 DDX11L8 HSP90AB1 DNAH10 DDX60 ABCB5 IDE MORC2 MLH3 IGHMBP2 SMARCA4 ATP1A4 DDX39A

CDK17 PSKH1 SPEG MAP3K4 KSR1 NEK1 GRK2 GRK3 BRAF PKM CAMK1D ADCK5 KSR2 CASK EGFR MTOR PRKAA1 PRKAA2 PRKCD PRKCI MAPK6 MAP3K21 PSKH2 NEK11

ABCA2 CCT3 MYO5B PSMC5 CHD3 BCS1L ABCB4 UBA1 MDN1 NAE1 DDX23 DDX60L ABCD1 DNAH8 DDX11L8 HSP90AB1 DNAH10 DDX60 MYO1H ABCB5 IDE MORC2 MLH3 IGHMBP2 SMARCA4 TMEM30A ATP1A4 DDX39A

CDK17 PSKH1 SPEG MAP3K4 KSR1 NEK1 BRAF CAMK1D KSR2 CASK MTOR PRKAA1 PRKAA2 PRKCD PRKCI MAPK6 MAP3K21 PSKH2 NEK11

SRC JAK3 PKM FGR LCK PRKCD HCK

GRM1 GRM5 GRM7 GRM8

GRM1 GRM5 GRM7 GRM8

ABCA2 CCT3 MYO5B BMS1 PSMC5 CHD3 BCS1L ABCB4 MDN1 DDX23 DDX60L ABCD1 DNAH8 DDX11L8 HSP90AB1 DNAH10 DDX60 ABCB5 IDE MORC2 GFM2 MLH3 IGHMBP2 SMARCA4 ATP1A4 DDX39A RASD2

RYR1 RYR2 RYR3

ABCA2 CCT3 MYO5B BMS1 PSMC5 CHD3 BCS1L ABCB4 MDN1 DDX23 DDX60L ABCD1 DNAH8 DDX11L8 HSP90AB1 DCPS DNAH10 DDX60 ABCB5 IDE MORC2 GFM2 MLH3 IGHMBP2 SMARCA4 ATP1A4 DDX39A RASD2

ABCA2 CCT3 MYO5B BMS1 PSMC5 CHD3 BCS1L ABCB4 MDN1 DDX23 DDX60L ABCD1 DNAH8 DDX11L8 HSP90AB1 DCPS DNAH10 DDX60 ABCB5 IDE MORC2 GFM2 MLH3 IGHMBP2 SMARCA4 ATP1A4 DDX39A RASD2

ABCA2 CCT3 MYO5B BMS1 PSMC5 CHD3 BCS1L ABCB4 MDN1 DDX23 DDX60L ABCD1 DNAH8 DDX11L8 HSP90AB1 DCPS DNAH10 DDX60 ABCB5 IDE MORC2 GFM2 MLH3 IGHMBP2 SMARCA4 ATP1A4 DDX39A RASD2

PDE1C ARPP21 PDE1B MYO5B RYR1 RYR2 RYR3 SPHK1 CAMK1D GRM7 CASK EGFR IQCB1

GRM1 GRM5 GABBR1

EPHB4 EPHA6 ALK DDR1 EGFR EPHA7 EPHB1

RYR1 RYR2 RYR3

EPHB4 EPHA6 EPHA7 EPHB1

EPHB4 EPHA6 ALK DDR1 EGFR EPHA7 EPHB1

PRKAA1 PRKAA2

PRKAA1 PRKAA2

GRM1 GRM5

PRKAA1 PRKAA2

MAP3K4 BRAF EGFR MAP3K21

GRM1 GRM5 GRM7 GRM8

PLOD1 PLOD3

PDE1C PDE1B

PDE1C PDE1B

PLOD1 PLOD3

ABCA2 ABCB4

ADAM20 SRC ITGA2B GPNMB ICAM2 S1PR3 TGFBI EGFR CD40LG

DDX23 DDX60L DDX11L8 DDX60 IGHMBP2 DDX39A

DDX23 DDX60L DDX11L8 DDX60 IGHMBP2 DDX39A

EPHA6 EPHA7 EPHB1

NDST4 NDST2

ABCA2 ABCB4

GRM1 GRM5

UBA1 NAE1

NDST4 NDST2

PLOD1 PLOD3

GRM7 GRM8

GRK2 GRK3

ALK HBEGF GRM5 EGFR

ADAM20 SRC EVPL ITGA2B EPS15L1 PKM GPNMB HSP90AB1 ANK3 ICAM2 ADGRL1 GLOD4 S1PR3 TGFBI EGFR PKP3 CD40LG ENO1

CHD3 DDX23 DDX60L DDX11L8 DDX60 IGHMBP2 SMARCA4 DDX39A

PRPSAP1 TRAF6 ACACA SRC CLASP2 RYR2 KSR1 BRAF SNAP91 NBEAL2 FGR HSF1 HSP90AB1 ADCY4 KSR2 LCK GRM5 CASK EGFR MTOR PRKAA1 APPL1 PRKCD MAPK6 ATP1A4

RYR1 RYR2 RYR3

KSR1 DLST HSF1 HSP90AB1 OGDH GUCY1B1 ENO1 HDAC2

PRPSAP1 PRPSAP2

KSR1 BRAF KSR2

ABCD1 SLC25A17

PRPSAP1 PRPSAP2

PDE1C PDE1B PDE8B

PLOD1 PLOD3 GYS2

RYR1 RYR2 RYR3 PRKAA1 PRKAA2 HDAC2

GRM1 GRM5 GRM7 GRM8

EPHB4 SRC GPNMB FGR ALK DDR1 LCK EGFR MTOR MAP3K21 HCK EPHA7 EPHB1

SRC FGR LCK APPL1 PRKCD HCK

SENP3 SRC JAK3 NAA25 GRK2 BRAF SPHK1 DHPS FNIP1 FGR PRMT7 HSF1 PLOD1 ALK DDR1 PLOD3 CAMK1D HBEGF LCK GRM5 EGFR MTOR PRKAA1 PRKAA2 PRKCD PRKCI HCK HDAC2 EPHA7 RASD2

SRC FGR APPL1 PRKCD HCK

SRC FGR APPL1 PRKCD HCK

TRAF6 SRC FGR LCK APPL1 PRKCD HCK

ADGRB2 GRK2 GPBAR1 ADCY4 ADGRG3 FPR1 ADGRL1 GRM1 GPR88 GRM5 GRM7 GRM8 S1PR3 GABBR1

SRC JAK3 FGR HSF1 ALK DDR1 HBEGF LCK GRM5 EGFR MTOR PRKCD HCK HDAC2 EPHA7

SRC NCF2 PKM ABCD1 OGDH MTOR PDE8B PRKAA1 PRKAA2 NT5C2 ENO1

SRC JAK3 FGR HSF1 ALK DDR1 HBEGF LCK GRM5 EGFR MTOR PRKCD HCK HDAC2 EPHA7

SRC NCF2 PKM ABCD1 OGDH MTOR PDE8B PRKAA1 PRKAA2 NT5C2 ENO1

PRPSAP1 PRPSAP2 NMNAT2 ACACA SRC NCF2 GNMT PKM DLST ABCD1 GPD2 ADCY4 OGDH CASK GUCY1B1 EHHADH MTOR PDE8B PRKAA1 PRKAA2 NT5C2 ENO1

GRM1 GRM5 GRM7 GRM8

ABCA2 SPHK1 PRKAA1 PRKCD

SRC TKTL1 AGL PKM XYLB GPD2 OGDH MTOR PRKAA1 PRKAA2 ENO1

PRPSAP1 PRPSAP2 ABCA2 ACACA SRC NDST4 DHDDS GNMT XYLT2 JAK3 GANAB PKM DLST XYLB ABCD1 PLOD1 GPD2 ADCY4 PLOD3 HBEGF NDST2 OGDH CASK GUCY1B1 EHHADH MTOR PDE8B PRKAA1 PRKAA2 XXYLT1 NT5C2 PRKCD ENO1

PRPSAP1 PRPSAP2 NMNAT2 ACACA SRC NCF2 PKM DLST ABCD1 GPD2 ADCY4 OGDH CASK GUCY1B1 EHHADH MTOR PDE8B PRKAA1 PRKAA2 NT5C2 ENO1

NMNAT2 SRC NCF2 PKM DLST GPD2 OGDH MTOR PRKAA1 PRKAA2 ENO1

NMNAT2 SRC NCF2 PKM DLST GPD2 OGDH MTOR PRKAA1 PRKAA2 ENO1

ABCB4 TMEM30A PRKCD

ABCA2 SPHK1 PRKAA1

SRC PKM ABCD1 OGDH MTOR PDE8B PRKAA1 PRKAA2 NT5C2 ENO1

SRC FGR APPL1 PRKCD HCK

SRC NCF2 PKM ABCD1 OGDH MTOR PDE8B PRKAA1 PRKAA2 NT5C2 ENO1

NMNAT2 SRC NCF2 PKM DLST GPD2 OGDH MTOR PRKAA1 PRKAA2 ENO1

SRC PKM ABCD1 OGDH MTOR PDE8B PRKAA1 PRKAA2 NT5C2 ENO1

EPHB4 EPHA6 SRC FSTL4 CLASP2 JAK3 BRAF FGR ALK DOCK3 DDR1 HBEGF HIP1R SESN3 IDE LCK EGFR PRKAA1 APPL1 PRKCD HCK EPHA7 EPHB1

SRC NCF2 PKM ABCD1 OGDH MTOR PDE8B PRKAA1 PRKAA2 NT5C2 ENO1

ADCY4 GRM1 GRM5 GRM7 GRM8 S1PR3 GABBR1

SRC NCF2 PKM OGDH MTOR PRKAA1 PRKAA2 ENO1

ALK DDR1 LCK EGFR

PRPSAP1 PRPSAP2 NMNAT2 ABCA2 ACACA SRC DHDDS NCF2 EFR3A GRK3 TTC7B PKM DLST PLCD1 XYLB ABCD1 GPD2 ADCY4 INPP5E OGDH CASK GUCY1B1 EHHADH MTOR PDE8B PRKAA1 PRKAA2 NT5C2 PRKCD ENO1

CCR9 ADGRB2 RYR1 RYR2 RYR3 SPHK1 LMCD1 KSR2 GRM1 GRM5 MTOR PRKAA1

MYO5B PSMC5 CLSTN2 GIT2 EFR3A DLGAP3 GRK2 BRAF SNAP91 SPHK1 SYN2 SLITRK3 GRM1 GRM5 GRM7 GRM8 CASK EGFR GUCY1B1 MTOR SLC6A5 HTR3B GABBR1 EPHA7 EPHB1 RASD2

MYO5B PSMC5 CLSTN2 GIT2 EFR3A DLGAP3 GRK2 BRAF SNAP91 SPHK1 SYN2 SLITRK3 GRM1 GRM5 GRM7 GRM8 CASK EGFR GUCY1B1 MTOR SLC6A5 HTR3B GABBR1 EPHA7 EPHB1 RASD2

PKM DLST GPD2 OGDH ENO1

SRC NCF2 PKM OGDH MTOR PRKAA1 PRKAA2 ENO1

EPHB4 TRAF6 SRC MAP3K4 GRK3 BRAF SPHK1 FNIP1 PLCD1 GPNMB HSF1 ALK HSP90AB1 DDR1 HBEGF LCK GRM5 EGFR MTOR PRKAA1 PRKAA2 PRKCD ENO1 HDAC2 EPHA7

EPHB4 TRAF6 SRC MAP3K4 GRK3 BRAF SPHK1 FNIP1 PLCD1 GPNMB HSF1 ALK HSP90AB1 DDR1 HBEGF LCK GRM5 EGFR MTOR PRKAA1 PRKAA2 PRKCD ENO1 HDAC2 EPHA7

MYO5B PSMC5 CLSTN2 GIT2 EFR3A DLGAP3 GRK2 BRAF SNAP91 SPHK1 SYN2 SLITRK3 GRM1 GRM5 GRM7 GRM8 CASK EGFR GUCY1B1 MTOR SLC6A5 HTR3B GABBR1 EPHA7 EPHB1 RASD2

PRPSAP1 PRPSAP2 NMNAT2 ACACA SRC NCF2 PKM DLST ABCD1 GPD2 ADCY4 OGDH CASK GUCY1B1 EHHADH MTOR PDE8B PRKAA1 PRKAA2 NT5C2 ENO1

PRPSAP1 PRPSAP2 ACACA SRC PKM DLST ABCD1 ADCY4 OGDH CASK GUCY1B1 EHHADH MTOR PDE8B PRKAA1 PRKAA2 NT5C2 ENO1

PDE1C RYR1 RYR2 RYR3 BRAF PLCD1 EGFR PRKAA1 PRKAA2

PRPSAP1 PRPSAP2 NMNAT2 ACACA SRC NCF2 PKM DLST ABCD1 GPD2 ADCY4 OGDH CASK GUCY1B1 EHHADH MTOR PDE8B PRKAA1 PRKAA2 NT5C2 ENO1

ABCA2 SPHK1 PRKAA1 PRKCD

SRC NCF2 PKM ABCD1 OGDH MTOR PDE8B PRKAA1 PRKAA2 NT5C2 PRKCD ENO1

NDST4 XYLT2 NDST2

RYR1 RYR2 RYR3

NIPBL DDX11L8 STAG3

SRC PKM OGDH CASK MTOR PRKAA1 PRKAA2 ENO1

SRC PKM OGDH CASK MTOR PRKAA1 PRKAA2 ENO1

SRC MTOR PRKAA1 PRKAA2 ENO1

MYO5B ADGRB2 CLSTN2 WLS BRAF SNAP91 ADGRL1 SLITRK3 GRM5 CASK EGFR MTOR PRKCI HDAC2 EPHB1

MYO5B PSMC5 CLSTN2 GIT2 EFR3A DLGAP3 GRK2 BRAF SNAP91 SPHK1 SYN2 SLITRK3 GRM1 GRM5 GRM7 GRM8 CASK EGFR GUCY1B1 MTOR SLC6A5 HTR3B GABBR1 EPHA7 EPHB1 RASD2

NMNAT2 PKM DLST GPD2 OGDH ENO1

HSF1 PRKAA1 PRKAA2

PRKAA1 PRKAA2 HDAC2

PRPSAP1 PRPSAP2 NMNAT2 ACACA SRC NCF2 GNMT PKM DLST ABCD1 GPD2 ADCY4 OGDH CASK GUCY1B1 EHHADH MTOR PDE8B PRKAA1 PRKAA2 NT5C2 ENO1

GRM1 GRM5

ABCA2 ABCB4

SRC HIP1R

SRC MTOR PRKAA1 PRKAA2

SRC MTOR PRKAA1 PRKAA2

SRC MTOR PRKAA1 PRKAA2

EPHB4 SRC LCK MTOR CD40LG

SRC PKM OGDH CASK MTOR PRKAA1 PRKAA2 ENO1

SRC PKM OGDH MTOR PRKAA1 PRKAA2 ENO1

ACOX3 ACAD11 ABCD1 SLC25A17 EHHADH MTOR

EPHB4 SRC LCK MTOR CD40LG

MYO5B DOCK11 SRC ADGRB2 PSMC5 CLASP2 CLSTN2 BRAF SNAP91 FNIP1 HSF1 HIP1R ADGRL1 SLITRK3 MORC2 MTOR HCK EPHB1

EPHB4 EPHA6 SRC EPHA7 EPHB1

SRC SPHK1 HSF1 PRKAA1 PRKCD HDAC2

RYR1 RYR2 RYR3

SPHK1 PRKAA1 PRKCD

SRC PKM OGDH MTOR PRKAA1 PRKAA2 ENO1

SRC MTOR PRKAA1 PRKAA2 ENO1

SRC MTOR PRKAA1 PRKAA2 ENO1

SRC PKM OGDH CASK MTOR PRKAA1 PRKAA2 ENO1

SRC NDST4 TKTL1 GNMT GANAB BRAF AGL PKM PLCD1 XYLB GPD2 NDST2 OGDH CASD1 MTOR GYS2 PRKAA1 PRKAA2 ENO1

SRC RYR1 RYR2 RYR3 JAK3 GRK2 PKM HSF1 ALK SESN3 IDE GRM5 IFIT1 GUCY1B1 MTOR PRKAA1 APPL1 PRKCD PRKCI HTR3B HDAC2

SRC PKM OGDH MTOR PRKAA1 PRKAA2 ENO1

SRC PKM OGDH MTOR PRKAA1 PRKAA2 ENO1

EPHA6 MYO5B SRC GAS2 FSTL4 CLASP2 WLS BRAF SNAP91 NBEAL2 PDZD8 FGR DDR1 PLOD3 ANK3 PLEKHG4 SLITRK3 PREX2 CASK IGF2BP1 CELSR3 EGFR SMARCA4 ARPIN HCK MYO16 EPB41L2 EPHA7 EPHB1

SRC CLASP2 HIP1R

PRKAA1 PRKAA2 KAT14 HDAC2

SRC PKM OGDH MTOR PRKAA1 PRKAA2 ENO1

FNIP1 MTOR

PRKAA1 PRKAA2

SNAP91 HIP1R

GPBAR1 MTOR

ABCB4 GPBAR1

SRC PKM OGDH MTOR PRKAA1 PRKAA2 ENO1

ACACA PRKAA1 PRKAA2

ABCB4 TMEM30A PRKCD

ACOX3 ACAD11 ABCD1 SLC25A17 EHHADH MTOR PRKAA1

ANO9 ABCA2 ABCB4 TMEM30A PRKCD

MYO5B PSMC5 CLSTN2 GIT2 DLGAP3 GRK2 BRAF SPHK1 GRM1 GRM5 GRM7 GRM8 CASK EGFR GUCY1B1 MTOR GABBR1 EPHA7 EPHB1

ACACA SRC PKM DLST ABCD1 ADCY4 OGDH CASK GUCY1B1 EHHADH MTOR PDE8B PRKAA1 PRKAA2 NT5C2 ENO1

TRAF6 MYO5B SRC ADGRB2 CLASP2 CLSTN2 EFR3A DLGAP3 GRK2 GRK3 BRAF NAE1 SYN2 DOCK1 HIP1R ADGRL1 LCK GRM1 GRM5 GRM7 GRM8 CELSR3 GUCY1B1 MTOR APPL1 PRKCI GABBR1 EPHA7 EPHB1

PDE1C PDE1B MAOB CCT3 MYO5B SRC DLGAP3 BRAF SNAP91 ALK HSP90AB1 HIP1R GRM1 GRM7 GRM8 CASK IGF2BP1 MTOR ASL IGHMBP2 PRKAA1 PRKAA2 CD40LG HTR3B GABBR1 EPHA7

MYO5B SNAP91 SYN2 GRM1 GRM5 CASK PRKCI GABBR1 EPHA7

PDE1C EPHA6 PDE1B MAOB MYO5B SRC CLSTN2 WLS DLGAP3 GRK2 GRK3 SNAP91 HSP90AB1 ADCY4 ANK3 HIP1R GRM1 GRM5 GRM7 GRM8 CASK IGF2BP1 MTOR ASL IGHMBP2 PRKAA1 PRKAA2 HTR3B GABBR1 EPHA7 EPHB1

EPHA6 MAOB MYO5B SRC CLSTN2 WLS DLGAP3 GRK2 GRK3 HSP90AB1 ADCY4 ANK3 HIP1R GRM1 GRM5 GRM7 CASK IGF2BP1 MTOR PRKAA1 PRKAA2 GABBR1 EPHA7 EPHB1

EPHA6 MAOB MYO5B SRC CLSTN2 WLS DLGAP3 GRK2 GRK3 HSP90AB1 ADCY4 ANK3 HIP1R GRM1 GRM5 GRM7 CASK IGF2BP1 MTOR PRKAA1 PRKAA2 GABBR1 EPHA7 EPHB1

SRC CLASP2 WLS KSR1 FGR DOCK8 HIP1R EGFR GABBR1 PSD4

SRC CLASP2 KSR1 FGR HIP1R EGFR PSD4

SRC CLSTN2 SNAP91 ANK3 HIP1R ADGRL1 SLITRK3 GRM1 GRM5 GRM7 GRM8 CASK CELSR3 SLC6A5 HTR3B ENO1 GABBR1 EPHA7

BRPF3 CCT3 MARCHF6 PSMC5 UBE4A NAA25 MORF4L1 HSF1 RIC1 HSP90AB1 DOCK1 PRAMEF22 POLG SESN3 IDE CCDC61 IGF2BP1 POLR3B CBX6 MTOR CIAO3 PRKAA1 PRKAA2 FBXO21 KAT14

EPHB4 CDK17 EPHA6 PSKH1 SPEG SRC WDR81 MAP3K4 JAK3 KSR1 NEK1 GRK2 GRK3 ACAD11 BRAF FGR ALK DDR1 CAMK1D ADCK5 KSR2 LCK CASK EGFR MTOR PRKAA1 PRKAA2 PRKCD PRKCI MAPK6 MAP3K21 PSKH2 HCK NEK11 EPHA7 EPHB1

EPHB4 CDK17 EPHA6 PSKH1 SPEG SRC MAP3K4 JAK3 KSR1 NEK1 GRK2 GRK3 BRAF FGR ALK DDR1 CAMK1D ADCK5 KSR2 LCK CASK EGFR PRKAA1 PRKAA2 PRKCD PRKCI MAPK6 MAP3K21 PSKH2 HCK NEK11 EPHA7 EPHB1

EPHB4 CDK17 EPHA6 PSKH1 SPEG SRC MAP3K4 JAK3 KSR1 NEK1 GRK2 GRK3 BRAF FGR ALK DDR1 CAMK1D KSR2 LCK CASK EGFR PRKAA1 PRKAA2 PRKCD PRKCI MAPK6 MAP3K21 PSKH2 HCK NEK11 EPHA7 EPHB1

EPHB4 CDK17 EPHA6 PSKH1 SPEG SRC MAP3K4 JAK3 NEK1 GRK2 GRK3 BRAF FGR ALK DDR1 CAMK1D ADCK5 LCK CASK EGFR PRKAA1 PRKAA2 PRKCD PRKCI MAPK6 MAP3K21 PSKH2 HCK NEK11 EPHA7 EPHB1

EPHB4 CDK17 EPHA6 PSKH1 SPEG SRC MAP3K4 JAK3 NEK1 GRK2 GRK3 BRAF FGR ALK CAMK1D LCK EGFR PRKAA1 PRKAA2 PRKCD PRKCI MAPK6 MAP3K21 PSKH2 HCK EPHA7 EPHB1

EPHB4 EPHA6 SRC JAK3 KSR1 BRAF FGR ALK DDR1 KSR2 LCK EGFR MAP3K21 HCK EPHA7 EPHB1

EPHB4 EPHA6 SRC JAK3 KSR1 BRAF FGR ALK DDR1 KSR2 LCK EGFR MAP3K21 HCK EPHA7 EPHB1

EPHB4 EPHA6 SRC JAK3 FGR ALK DDR1 LCK EGFR MAP3K21 HCK EPHA7 EPHB1

EPHB4 EPHA6 SRC JAK3 FGR ALK DDR1 LCK EGFR MAP3K21 HCK EPHA7 EPHB1

EPHB4 EPHA6 SRC JAK3 FGR ALK DDR1 LCK EGFR HCK EPHA7 EPHB1

EPHB4 EPHA6 SRC JAK3 FGR ALK DDR1 LCK EGFR HCK EPHA7 EPHB1

DOCK11 CLASP2 TRIP12 NCAPG2 RYR3 EFR3A NBEAL2 ANKAR NIPBL DOCK1 DOCK3 INTS7 DOCK8 IPO9 MTOR PKP3 IQCB1 LTN1 DAAM2 STAG3

CDK17 PSKH1 SPEG MAP3K4 KSR1 NEK1 GRK2 GRK3 BRAF CAMK1D KSR2 CASK PRKAA1 PRKAA2 PRKCD PRKCI MAPK6 MAP3K21 PSKH2 NEK11

CDK17 PSKH1 SPEG MAP3K4 KSR1 NEK1 GRK2 GRK3 BRAF CAMK1D KSR2 CASK PRKAA1 PRKAA2 PRKCD PRKCI MAPK6 MAP3K21 PSKH2 NEK11

CDK17 PSKH1 SPEG MAP3K4 KSR1 NEK1 GRK2 GRK3 BRAF CAMK1D KSR2 CASK PRKAA1 PRKAA2 PRKCD PRKCI MAPK6 MAP3K21 PSKH2 NEK11

CLASP2 TRIP12 NCAPG2 EFR3A NBEAL2 ANKAR NIPBL INTS7 DOCK8 IPO9 MTOR PKP3 IQCB1 LTN1 DAAM2 STAG3

GRM1 GRM5 GRM7 GRM8

RYR1 RYR2 RYR3

RYR1 RYR2 RYR3

RYR1 RYR2 RYR3

RYR1 RYR2 RYR3

RYR1 RYR2 RYR3

CDK17 PSKH1 SPEG MAP3K4 NEK1 GRK2 GRK3 BRAF CAMK1D KSR2 CASK PRKAA1 PRKAA2 PRKCD PRKCI MAPK6 PSKH2 NEK11

GRM1 GRM5 GRM7 GRM8 GABBR1

GRM1 GRM5 GRM7 GRM8 GABBR1

GRM1 GRM5 GRM7 GRM8 GABBR1

GRM1 GRM5 GRM7 GRM8 GABBR1

GRM1 GRM5 GRM7 GRM8 GABBR1

GRM1 GRM5 GRM7 GRM8 GABBR1

DOCK11 DOCK1 DOCK3 DOCK8

DOCK11 DOCK1 DOCK3 DOCK8

DOCK11 DOCK1 DOCK3 DOCK8

DOCK11 DOCK1 DOCK3 DOCK8

DOCK11 DOCK1 DOCK3 DOCK8

DOCK11 DOCK1 DOCK3 DOCK8

DOCK11 DOCK1 DOCK3 DOCK8

DOCK11 DOCK1 DOCK3 DOCK8

GRM1 GRM5 GRM7 GRM8

GRM1 GRM5 GRM7 GRM8

EPHB4 EPHA6 EPHA7 EPHB1

EPHB4 EPHA6 EPHA7 EPHB1

EPHB4 EPHA6 EPHA7 EPHB1

EPHB4 EPHA6 EPHA7 EPHB1

EPHB4 EPHA6 EPHA7 EPHB1

EPHB4 EPHA6 EPHA7 EPHB1

EPHB4 EPHA6 EPHA7 EPHB1

EPHB4 EPHA6 EPHA7 EPHB1

EPHB4 EPHA6 EPHA7 EPHB1

EPHB4 EPHA6 EPHA7 EPHB1

GRM1 GRM5 GRM7 GRM8

ABCA2 PSMC5 BCS1L ABCB4 MDN1 ABCD1 DNAH8 DNAH10 ABCB5 IGHMBP2

ABCA2 PSMC5 BCS1L ABCB4 MDN1 ABCD1 DNAH8 DNAH10 ABCB5 IGHMBP2

RYR1 RYR2 RYR3

RYR1 RYR2 RYR3

RYR1 RYR2 RYR3

RYR1 RYR2 RYR3

RYR1 RYR2 RYR3

RYR1 RYR2 RYR3

RYR1 RYR2 RYR3

RYR1 RYR2 RYR3

CLASP2 TRIP12 NCAPG2 EFR3A ANKAR NIPBL INTS7 IPO9 MTOR PKP3 DAAM2 STAG3

KSR1 BRAF PDZD8 KSR2 PRKCD PRKCI

GRM1 GRM5 GRM7 GRM8 GABBR1

GRM1 GRM5 GRM7 GRM8 GABBR1

GRM1 GRM5 GRM7 GRM8

KSR1 KSR2

GRM1 GRM5

PRKAA1 PRKAA2

GRM1 GRM5

HSF1 HSF2

GRM1 GRM5

HSF1 HSF2

GRM1 GRM5

PRKAA1 PRKAA2

GRM1 GRM5

KSR1 KSR2

GRM1 GRM5 GRM7 GRM8 GABBR1

KSR1 BRAF PDZD8 KSR2 PRKCD PRKCI

KSR1 BRAF PDZD8 KSR2 PRKCD PRKCI

RYR1 RYR2 RYR3

RYR1 RYR2 RYR3

RYR1 RYR2 RYR3

RYR1 RYR2 RYR3

KSR1 BRAF PDZD8 KSR2 PRKCD PRKCI

KSR1 BRAF PDZD8 KSR2 PRKCD PRKCI

EPHB4 EPHA6 EPHA7 EPHB1

EPHB4 EPHA6 EPHA7 EPHB1

ADGRB2 ADGRL1 CELSR3

ADGRB2 ADGRL1 CELSR3

ABCA2 MYO5B BMS1 NDST4 PSMC5 CHD3 BCS1L ABCB4 MDN1 DDX23 DDX60L ABCD1 DNAH8 DNAH10 DDX60 ABCB5 NDST2 GFM2 CASK IGHMBP2 IQCB1 SMARCA4 DDX39A MYO16 RASD2

PLOD1 PLOD3

PDE1C PDE1B

PLOD1 PLOD3

PDE1C PDE1B

NT5DC3 NT5C2

MDN1 DNAH8 DNAH10

MDN1 DNAH8 DNAH10

CHD3 DDX23 DDX60L DDX60 IGHMBP2 SMARCA4 DDX39A

CHD3 DDX23 DDX60L DDX60 IGHMBP2 SMARCA4 DDX39A

ABCA2 BMS1 NDST4 PSMC5 CHD3 BCS1L ABCB4 MDN1 DDX23 DDX60L ABCD1 DNAH8 DNAH10 DDX60 ABCB5 NDST2 GFM2 CASK IGHMBP2 SMARCA4 DDX39A RASD2

EPHB4 SRC ITGA2B FGR LCK HCK EPHB1

SRC GRK2 GRK3 FGR LCK EGFR PRKCD HCK

GRM1 GRM5 GRM7 GRM8 GABBR1

GRM1 GRM5 GRM7 GRM8 GABBR1

MAOB SRC FGR LCK PRKCD HCK

EPHA6 SRC FGR LCK HCK EPHA7

PDE1C TRAF6 PDE1B SRC PSMC5 CHD3 GRK2 ADCY4 HBEGF LCK PREX2 EGFR CBX6 MTOR PRKCD HDAC2

PDE1C TRAF6 PDE1B SRC PSMC5 CHD3 GRK2 ADCY4 HBEGF LCK PREX2 EGFR MTOR PRKCD

PDE1C PDE1B GRK2 ADCY4 PRKCD

GPNMB HBEGF EGFR

GPNMB HBEGF EGFR

TRAF6 SRC NCF2 KSR1 DOCK3 IGF2BP1 MTOR PRKAA1 PRKAA2 PRKCD

TRAF6 SRC FGR LCK HCK

PDE1C PDE1B RYR1 RYR2 RYR3 SPHK1 PLCD1 ADCY4 GRM1 GRM5 EGFR

DLGAP3 GRM1 GRM5 CASK EPB41L2

SRC ITGA2B FGR LCK EGFR HCK

EPHB4 EPHA6 SRC EPHA7 EPHB1

SRC GIT2 ITGA2B BRAF DOCK1 CAPN11 CAPN7 MAPK6

SRC GIT2 ITGA2B BRAF DOCK1 CAPN11 CAPN7 MAPK6

GRM1 GRM5 GRM7 GRM8 GABBR1

PDE1C PDE1B GRK2 ADCY4 PRKCD

CCR9 ADGRB2 GPBAR1 LPAR5 FPR1 ADGRL1 GRM1 GRM5 GRM7 GRM8 S1PR3 CELSR3 GABBR1

SRC ITGA2B KSR1 BRAF KSR2

PDE1C PDE1B GRK2 ADCY4 PRKCD

GRM1 GRM5 GRM7 GRM8 GABBR1

SRC ITGA2B KSR1 BRAF KSR2

PDE1C PDE1B GRK2 ADCY4 PRKCD

ACACA PRKAA1 PRKAA2

RYR1 RYR2 RYR3

PKM PRKAA1 ENO1

PDE1C PDE1B CCR9 SRC GRK2 ADCY4 LPAR5 FPR1 GRM7 GRM8 S1PR3 PRKCD GABBR1

DLST PLOD1 PLOD3 OGDH EHHADH

DLGAP3 SLITRK3 GRM1 GRM5 CASK EPB41L2

ACACA MAOB GNMT DLGAP3 GRM1 GRM5 GRM7 GRM8 EGFR MTOR PRKAA1 PRKAA2 PRKCD HTR3B GABBR1

SRC ITGA2B KSR1 BRAF KSR2

SRC BRAF HSP90AB1 PRKAA1 PRKAA2 PRKCD

SRC FGR LCK HCK

Synergistic drug combinations for cancer identified in a CRISPR screen for pairwise genetic interactions.

EPHB4 SRC MAP3K4 JAK3 KSR1 GRK2 SPHK1 PLOD1 ALK HSP90AB1 DDR1 CAMK1D LCK CASK IGF2BP1 EGFR PRKAA1 PRKCD HCK

Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition.

PSKH1 KLHL32 KSR1 AREL1 BRAF FGR ALK HSP90AB1 KLHL6 DDR1 POGK KSR2 LCK EGFR PRKAA1 PRKAA2 PRKCI PSKH2 HCK NEK11 EPHB1

The protein tyrosine kinase family of the human genome.

EPHB4 EPHA6 SRC JAK3 FGR ALK DDR1 LCK EGFR HCK EPHA7 EPHB1

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

EPHB4 ABCA2 ACACA MORN1 SPEG ADGRB2 CLASP2 ARHGEF11 RYR1 ACOX3 JAK3 EPS15L1 MDN1 SPHK1 NBEAL2 PDZD8 ABCD1 RIC1 DOCK3 PLOD3 LPAR5 INPP5E POLG KSR2 HIP1R TRMT1 ADGRL1 CELSR3 MTOR XXYLT1 PCNX1 DISP2 ZNF324B TOP3A RASD2

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

PDE1B CCT3 DOCK11 SENP3 SRC ADGRB2 WDR81 CLASP2 GIT2 ARHGEF11 DLGAP3 EPS15L1 UBA1 MDN1 SNAP91 MORF4L1 NIPBL HSP90AB1 ANK3 KSR2 GRM1 GRM5 CASK MTOR NT5C2 SMARCA4 APPL1 PRKCI ENO1 EPB41L2 HDAC2

KAP1 facilitates reinstatement of heterochromatin after DNA replication.

PRPSAP1 PRPSAP2 ACACA CCT3 PSMC5 TRIP12 NCAPG2 MAP3K4 AGL PKM DNAH8 NIPBL POGK TRMT1 MORC2 IGF2BP1 POLR3B MTOR MRPS26 LTN1 SMARCA4 PRKCI DDX39A EPB41L2

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

NMNAT2 DYM ACACA EPHA6 MORN1 SRC CLASP2 CHD3 EPS15L1 GRK3 ANKAR FNIP1 XYLB PLOD1 RIC1 DOCK1 DDR1 ANK3 POLG KSR2 ADGRL1 PARD3B SLITRK3 IDE OGDH CASK EGFR PKP3 SLC16A14 XPNPEP3 PRKAA2 XXYLT1 NT5C2 PRKCI MAPK6 FBXO21

Reduced AMPK-ACC and mTOR signaling in muscle from older men, and effect of resistance exercise.

ACACA MTOR PRKAA1 PRKAA2

Phosphorylation of BRAF by AMPK impairs BRAF-KSR1 association and cell proliferation.

KSR1 BRAF PRKAA1 PRKAA2

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.

EPHB4 SRC FASTKD5 ACOX3 MAP3K4 KSR1 NEK1 ACAD11 BRAF DHPS DDX60L PLOD1 KLHL6 DDR1 PLOD3 LCK EGFR CAPN7 PRKAA1 PRKAA2 PRKCD PRKCI MAPK6 MAP3K21 HCK HDAC2 EPHA7

Expression cloning of GABA(B) receptors uncovers similarity to metabotropic glutamate receptors.

GRM1 GRM5 GRM7 GRM8 GABBR1

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

ACACA DOCK11 SPEG CLASP2 ARHGEF11 TRIP12 RYR3 MAP3K4 MDN1 NBEAL2 DDX23 PLOD1 RIC1 PLOD3 ANK3 MORC2 KIAA0825 CAPN7 IGHMBP2

Defining the membrane proteome of NK cells.

ABCA2 MFSD6 MARCHF6 PSMC5 CLASP2 TUBGCP2 NCAPG2 ACOX3 KSR1 EPS15L1 GANAB MDN1 GRK2 NBEAL2 PDZD8 DLST ABCD1 SLC25A17 HSP90AB1 DOCK8 ICAM2 IPO9 MTOR IGHMBP2 SMARCA4 TMEM30A DDX39A ENO1 PSD4

Mouse screen reveals multiple new genes underlying mouse and human hearing loss.

PRPSAP2 BRPF3 RSAD1 TRAF6 SRC SLC25A30 NCF2 GIT2 MDN1 NBEAL2 DHPS ABCD1 PRMT7 LPAR5 PRAMEF22 SESN3 IDE GRM8 OGDH CAPN11 EGFR CBX6 MTOR GYS2 XXYLT1 TMEM30A ARPIN DAAM2 ILDR1 KAT14

Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.

EPHB4 NMNAT2 ADAM20 SRC KCNH6 NEK1 UBA1 BRAF FGR CAMK1D DNAH10 LCK CAPN11 ADAMTS10 POLR3B EGFR SMARCA4 PRKCD PRKCI MAPK6 HCK HDAC2

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.

CCT3 SENP3 PSMC5 CHD3 TUBGCP2 TRIP12 MDN1 MORF4L1 DDX23 NIPBL HSP90AB1 DOCK1 DOCK8 HIP1R EXOC5 IPO9 PKP3 SMARCA4 DDX39A

Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network.

TRAF6 SRC MAP3K4 BRAF PKM HSP90AB1 LCK GRM5 EGFR MTOR PRKAA2 APPL1 PRKCD HCK HDAC2

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

ACACA CCT3 BMS1 PSMC5 FASTKD5 CLASP2 UBE4A UBA1 GANAB MDN1 PKM DLST NIPBL HSP90AB1 GPD2 ADCY4 DNAH10 GLOD4 IDE GRM1 OGDH IGF2BP1 IPO9 MTOR WDR6 PRKAA2 SMARCA4 PRKCD PRKCI ENO1 EPB41L2

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

CDK17 PDE1C CCT3 MYO5B CLASP2 CHD3 ARHGEF11 DLGAP3 EPS15L1 UBA1 GRK2 TTC7B SNAP91 PKM SYN2 DLST HSP90AB1 GPD2 ADCY4 ANK3 DOCK8 ADGRL1 GRM1 GRM5 OGDH NT5DC3 CASK PRKAA1 SMARCA4 HCK EPB41L2

Competitive binding of E3 ligases TRIM26 and WWP2 controls SOX2 in glioblastoma.

CCT3 PSMC5 EVPL CHD3 KCTD1 TRIP12 RYR1 UBA1 DLST PLCD1 KSR2 HIP1R GLOD4 IDE PKP3 MRPS26 XPNPEP3 PRKCD DDX39A ENO1 EPHA7

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

PRPSAP1 DYM CCT3 BMS1 PSMC5 FASTKD5 TUBGCP2 NCAPG2 UBE4A GANAB MDN1 DDX23 DLST DDX60L PLOD1 GPD2 PLOD3 DDX60 MRPL45 OGDH IFIT1 GFM2 EXOC5 IGF2BP1 POLR3B IPO9 MTOR WDR6 MRPS26 LTN1 ENO1

Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.

ACACA CCT3 BMS1 PSMC5 TIPRL EPS15L1 NAA25 UBA1 AGL NAE1 PKM DLST GPNMB PLOD1 HSP90AB1 GPD2 DCPS HIP1R TRMT1 MUC5B GLOD4 IDE OGDH IFIT1 IPO9 MTOR PRKAA1 ARPIN DDX39A ENO1

Network organization of the human autophagy system.

ACACA CCT3 PSMC5 FREM1 GANAB AGL FNIP1 PRMT7 DOCK1 PLOD3 MRPL45 MTOR PRKAA1 PRKAA2 PRKCI DDX39A

Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair.

PRPSAP1 PRPSAP2 CCT3 BMS1 PSMC5 CLASP2 UBA1 ACAD11 CIZ1 PKM DDX23 DLST HSP90AB1 IGF2BP1 MRPS26 XPNPEP3 MAPK6 ENO1

Variability in Streptavidin-Sepharose Matrix Quality Can Significantly Affect Proximity-Dependent Biotinylation (BioID) Data.

PRPSAP2 SENP3 SRC FASTKD5 BCS1L NCAPG2 DLST PLOD1 QSOX2 POLG MRPL45 IDE OGDH NT5DC3 MRPS26 XPNPEP3

In vitro tyrosine phosphorylation of PLC-gamma 1 and PLC-gamma 2 by src-family protein tyrosine kinases.

SRC LCK EGFR HCK

Type 1 and type 3 ryanodine receptors are selectively involved in muscarinic antinociception in mice: an antisense study.

RYR1 RYR2 RYR3

Deficiency of the Hck and Src tyrosine kinases results in extreme levels of extramedullary hematopoiesis.

SRC FGR HCK

Inhibiting EGF receptor or SRC family kinase signaling overcomes BRAF inhibitor resistance in melanoma.

SRC BRAF EGFR

Heterogeneous gene expression and functional activity of ryanodine receptors in resistance and conduit pulmonary as well as mesenteric artery smooth muscle cells.

RYR1 RYR2 RYR3

Identification by amino acid sequencing of three major regulatory phosphorylation sites on rat acetyl-CoA carboxylase.

ACACA PRKAA1 PRKAA2

SPRY domains in ryanodine receptors (Ca(2+)-release channels).

RYR1 RYR2 RYR3

Ryanodine receptors are expressed in epidermal keratinocytes and associated with keratinocyte differentiation and epidermal permeability barrier homeostasis.

RYR1 RYR2 RYR3

Phorbol 12-myristate 13-acetate induces epidermal growth factor receptor transactivation via protein kinase Cdelta/c-Src pathways in glioblastoma cells.

SRC EGFR PRKCD

Isoform-dependent formation of heteromeric Ca2+ release channels (ryanodine receptors).

RYR1 RYR2 RYR3

α-enolase promotes tumorigenesis and metastasis via regulating AMPK/mTOR pathway in colorectal cancer.

MTOR PRKAA1 ENO1

Calcineurin upregulates local Ca(2+) signaling through ryanodine receptor-1 in airway smooth muscle cells.

RYR1 RYR2 RYR3

Identification of mutations in the cardiac ryanodine receptor gene in families affected with arrhythmogenic right ventricular cardiomyopathy type 2 (ARVD2).

RYR1 RYR2 RYR3

Chromosomal localization of murine ryanodine receptor genes RYR1, RYR2, and RYR3 by in situ hybridization.

RYR1 RYR2 RYR3

Regulation of mouse egg activation: presence of ryanodine receptors and effects of microinjected ryanodine and cyclic ADP ribose on uninseminated and inseminated eggs.

RYR1 RYR2 RYR3

The ryanodine receptor/calcium channel genes are widely and differentially expressed in murine brain and peripheral tissues.

RYR1 RYR2 RYR3

Bidirectional coupling between ryanodine receptors and Ca2+ release-activated Ca2+ (CRAC) channel machinery sustains store-operated Ca2+ entry in human T lymphocytes.

RYR1 RYR2 RYR3

Developmental changes in expression of the three ryanodine receptor mRNAs in the mouse brain.

RYR1 RYR2 RYR3

Ca(2+)-induced Ca2+ release in myocytes from dyspedic mice lacking the type-1 ryanodine receptor.

RYR1 RYR2 RYR3

Molecular identification of the ryanodine receptor pore-forming segment.

RYR1 RYR2 RYR3

Phosphorylation of dedicator of cytokinesis 1 (Dock180) at tyrosine residue Y722 by Src family kinases mediates EGFRvIII-driven glioblastoma tumorigenesis.

SRC DOCK1 EGFR

The regulation of hippocampal LTP by the molecular switch, a form of metaplasticity, requires mGlu5 receptors.

GRM1 GRM5 GRM7

Expression of the ryanodine receptor type 3 calcium release channel during development and differentiation of mammalian skeletal muscle cells.

RYR1 RYR2 RYR3

A gene-specific cerebral types 1, 2, and 3 RyR protein knockdown induces an antidepressant-like effect in mice.

RYR1 RYR2 RYR3

The organization of proteins in the human red blood cell membrane. A review.

RYR1 RYR2 RYR3

A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.

SENP3 FASTKD5 TUBGCP2 BCS1L UBE4A DDX23 DLST HSP90AB1 GPD2 CASK EXOC5 POLR3B IPO9 WDR6 PRKAA1 LTN1 EPB41L2 HDAC2

Network organization of the huntingtin proteomic interactome in mammalian brain.

PDE1B CCT3 MYO5B PSMC5 EPS15L1 GRK2 SNAP91 PKM HSP90AB1 GPD2 DOCK8 OGDH EHHADH MTOR PRKCD ATP1A4 ENO1 HCK EPB41L2

A long non-coding RNA specifically expressed in early embryos programs the metabolic balance in adult mice.

ACACA PKM MTOR PRKAA1 PRKAA2 ENO1

Requirement for the Mitochondrial Pyruvate Carrier in Mammalian Development Revealed by a Hypomorphic Allelic Series.

AGL DLST OGDH MTOR GYS2 PRKAA1 PRKAA2 ENO1

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

EPHB4 CDK17 BMS1 FASTKD5 CLASP2 BCS1L NCAPG2 EFR3A UBE4A GANAB MDN1 NAE1 DHPS CIZ1 DDX23 PDZD8 DLST PLOD1 PLOD3 ANK3 MRPL45 OGDH CCDC61 CASK EXOC5 EGFR WDR6 MRPS26 PRKCI EPB41L2 EPHA7

Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.

PRPSAP1 PRPSAP2 ACACA CCT3 CLASP2 UBA1 GANAB AGL MORF4L1 PKM DDX23 HSF1 PLOD1 NIPBL HSP90AB1 GPD2 PLOD3 INTS7 TRMT1 GLOD4 IGF2BP1 EGFR PKP3 MRPS26 XPNPEP3 PRKAA1 SMARCA4 ENO1 EPB41L2 HDAC2

FBXO32 links ubiquitination to epigenetic reprograming of melanoma cells.

PRPSAP1 ACACA TRIP12 AGL NAE1 MORF4L1 DHPS TRMT1 IPO9 SMARCA4 APPL1

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

ABCA2 TRAF6 TRIP12 ZNF785 RYR3 UBE4A EPS15L1 NAA25 TTC7B MORF4L1 PKM PDZD8 DLST NIPBL HSP90AB1 DOCK3 ANK3 POLG SESN3 CASK POLR3B CELSR3 GUCY1B1 CIAO3 ATRNL1 SMARCA4 APPL1 DAAM2

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

PRPSAP2 ACACA ADGRB2 RYR2 DLGAP3 EPS15L1 UBA1 GRK2 PKM SYN2 DLST HSP90AB1 DOCK3 ANK3 HIP1R ADGRL1 GRM5 OGDH NT5DC3 GUCY1B1 IGHMBP2 APPL1 ENO1 EPB41L2 GABBR1 HDAC2

Combinatorial CRISPR-Cas9 screens for de novo mapping of genetic interactions.

SRC BRAF ALK EGFR MTOR SMARCA4 HDAC2

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

CDK17 CCT3 CLASP2 TUBGCP2 EPS15L1 UBA1 GANAB GPATCH11 CIZ1 PKM DDX23 HSF1 HSF2 PLOD1 NIPBL POGK IDE LCK ZNF8 IGF2BP1 MRPS26 SMARCA4 PRKCI DDX39A TOP3A HDAC2

Transformation and Stat activation by derivatives of FGFR1, FGFR3, and FGFR4.

SRC LCK EGFR HCK

Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression.

MYO5B TRIP12 MDN1 PKM NIPBL HSP90AB1 DDX60 HIP1R PKP3 ENO1 STAG3 HDAC2

Polymorphisms in innate immunity genes and patients response to dendritic cell-based HIV immuno-treatment.

TRAF6 CCR9 SRC NCF2 PLCD1 FGR FPR1 LCK HCK

RT loop flexibility enhances the specificity of Src family SH3 domains for HIV-1 Nef.

SRC LCK HCK

Ryanodine receptor calcium release channels: lessons from structure-function studies.

RYR1 RYR2 RYR3

Partial cloning and differential expression of ryanodine receptor/calcium-release channel genes in human tissues including the hippocampus and cerebellum.

RYR1 RYR2 RYR3

Decreased nociceptive sensitization in mice lacking the fragile X mental retardation protein: role of mGluR1/5 and mTOR.

GRM1 GRM5 MTOR

Conserved and divergent functions of Nfix in skeletal muscle development during vertebrate evolution.

RYR1 RYR2 RYR3

A glutathione deficit alters dopamine modulation of L-type calcium channels via D2 and ryanodine receptors in neurons.

RYR1 RYR2 RYR3

Induction of lysosomal and mitochondrial biogenesis by AMPK phosphorylation of FNIP1.

FNIP1 PRKAA1 PRKAA2

Activation of the phosphoinositide 3-kinase-Akt-mammalian target of rapamycin signaling pathway is required for metabotropic glutamate receptor-dependent long-term depression.

GRM1 GRM5 MTOR

AMPK signaling in contracting human skeletal muscle: acetyl-CoA carboxylase and NO synthase phosphorylation.

ACACA PRKAA1 PRKAA2

Ablation of AMP-activated protein kinase alpha1 and alpha2 from mouse pancreatic beta cells and RIP2.Cre neurons suppresses insulin release in vivo.

PRKAA1 PRKAA2 PRKCD

Targeted Therapy in Brain Metastases: Ready for Primetime?

BRAF ALK EGFR

Cardioprotective effects of short-term caloric restriction are mediated by adiponectin via activation of AMP-activated protein kinase.

ACACA PRKAA1 PRKAA2

Acute exercise does not cause sustained elevations in AMPK signaling or expression.

ACACA PRKAA1 PRKAA2

Increase of ryanodine receptors by dopamine D1 receptors is negatively regulated by γ-aminobutyric acid type B receptors in primary cultures of mouse cerebral cortical neurons.

RYR1 RYR2 GABBR1

Requirement for the ryanodine receptor type 3 for efficient contraction in neonatal skeletal muscles.

RYR1 RYR2 RYR3

Identifying biological pathways that underlie primordial short stature using network analysis.

CCT3 MYO5B SRC PSMC5 CHD3 TRIP12 UBA1 GANAB MDN1 CIZ1 PKM DDX23 PLOD1 NIPBL HSP90AB1 GPD2 IGF2BP1 PKP3 XPNPEP3 PRKAA1 SMARCA4 ENO1 EPB41L2 HDAC2

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

BMS1 PSMC5 EVPL TIPRL NCAPG2 DLGAP3 GANAB ACAD11 AGL DHPS PLOD1 QSOX2 PLOD3 IDE CASK IGF2BP1 MTOR WDR6 PKP3 PRKAA1 PRKAA2 LTN1 FBXO21

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

CCT3 MYO5B BMS1 PSMC5 CLASP2 TIPRL EFR3A UBA1 GANAB TTC7B DHPS PDZD8 PLOD1 HSP90AB1 GPD2 PLOD3 ANK3 IDE CCDC61 CASK IPO9 EGFR LTN1 PRKCI

Human ISG15 conjugation targets both IFN-induced and constitutively expressed proteins functioning in diverse cellular pathways.

CCT3 GANAB PKM PLOD1 HSP90AB1 PLOD3 OGDH IFIT1 ENO1

CIN85 associates with TNF receptor 1 via Src and modulates TNF-alpha-induced apoptosis.

SRC FGR LCK HCK

Ephrin Ligands and Eph Receptors Show Regionally Restricted Expression in the Developing Palate and Tongue.

EPHB4 EPHA6 EPHA7 EPHB1

The SRC-family tyrosine kinase HCK shapes the landscape of SKAP2 interactome.

SRC FGR LCK HCK

Identification of an evolutionarily conserved superfamily of DOCK180-related proteins with guanine nucleotide exchange activity.

DOCK11 DOCK1 DOCK3 DOCK8

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

CCT3 MYO5B CHD3 TKTL1 EPX TRIP12 RYR2 FER1L6 ABCB4 FRA10AC1 MDN1 SNAP91 PKM DDX23 DLST DNAH8 NIPBL HSP90AB1 ABCB5 OGDH CAPN11 KIAA0825 CIAO3 MAPK6 ATP1A4 DDX39A ENO1 HDAC2 UTP14C

Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.

DOCK11 GIT2 ARHGEF11 EPS15L1 UBA1 GANAB PLOD1 DOCK1 DOCK3 PLEKHG4 DOCK8 GLOD4 PREX2 CASK WDR6 MRPS26 NT5C2 SMARCA4 APPL1 DDX39A EPB41L2 HDAC2

Frequency of driver mutations in lung adenocarcinoma from female never-smokers varies with histologic subtypes and age at diagnosis.

BRAF ALK EGFR

Heat shock factor 1 represses estrogen-dependent transcription through association with MTA1.

CHD3 HSF1 HDAC2

Protein kinase C-epsilon regulates local calcium signaling in airway smooth muscle cells.

RYR1 RYR2 RYR3

IL-33 and M2a alveolar macrophages promote lung defense against the atypical fungal pathogen Pneumocystis murina.

SRC FGR HCK