Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionGDP phosphatase activity

GBP2 GBP3

1.49e-0512102GO:0004382
GeneOntologyMolecularFunctionnucleoside diphosphate phosphatase activity

GBP2 GBP3

4.27e-0520102GO:0017110
GeneOntologyMolecularFunctionspectrin binding

GBP2 GBP3

1.26e-0434102GO:0030507
GeneOntologyMolecularFunctionlipopolysaccharide binding

GBP2 GBP3

2.52e-0448102GO:0001530
GeneOntologyMolecularFunctionHsp90 protein binding

GBP2 GBP3

3.31e-0455102GO:0051879
GeneOntologyMolecularFunctionG protein activity

GBP2 GBP3

3.80e-0459102GO:0003925
GeneOntologyMolecularFunctionGTPase activity

GBP7 GBP2 GBP3

5.42e-04341103GO:0003924
GeneOntologyMolecularFunctionGTP binding

GBP7 GBP2 GBP3

8.44e-04397103GO:0005525
GeneOntologyMolecularFunctionlipid binding

ESYT2 GBP2 GBP3 MYO1B

9.84e-04988104GO:0008289
GeneOntologyMolecularFunctionguanyl ribonucleotide binding

GBP7 GBP2 GBP3

1.13e-03439103GO:0032561
GeneOntologyMolecularFunctionguanyl nucleotide binding

GBP7 GBP2 GBP3

1.13e-03439103GO:0019001
GeneOntologyMolecularFunctionGDP binding

GBP2 GBP3

1.15e-03103102GO:0019003
GeneOntologyMolecularFunctionactin binding

GBP2 GBP3 MYO1B

1.45e-03479103GO:0003779
GeneOntologyMolecularFunctionGTPase regulator activity

VPS9D1 GBP2 GBP3

1.71e-03507103GO:0030695
GeneOntologyMolecularFunctionnucleoside-triphosphatase regulator activity

VPS9D1 GBP2 GBP3

1.71e-03507103GO:0060589
GeneOntologyMolecularFunctioncytokine binding

GBP2 GBP3

2.65e-03157102GO:0019955
GeneOntologyMolecularFunctionheat shock protein binding

GBP2 GBP3

2.85e-03163102GO:0031072
GeneOntologyMolecularFunctionendopeptidase inhibitor activity

GBP2 GBP3

3.47e-03180102GO:0004866
GeneOntologyMolecularFunctionpeptidase inhibitor activity

GBP2 GBP3

3.74e-03187102GO:0030414
GeneOntologyMolecularFunctionendopeptidase regulator activity

GBP2 GBP3

4.30e-03201102GO:0061135
GeneOntologyMolecularFunctionribonucleoside triphosphate phosphatase activity

GBP7 GBP2 GBP3

5.70e-03775103GO:0017111
GeneOntologyMolecularFunctionprotein homodimerization activity

GBP7 GBP2 GBP3

6.55e-03815103GO:0042803
GeneOntologyMolecularFunctionpeptidase regulator activity

GBP2 GBP3

6.94e-03257102GO:0061134
GeneOntologyMolecularFunctionpyrophosphatase activity

GBP7 GBP2 GBP3

7.11e-03839103GO:0016462
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides

GBP7 GBP2 GBP3

7.13e-03840103GO:0016817
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

GBP7 GBP2 GBP3

7.13e-03840103GO:0016818
GeneOntologyMolecularFunctionphosphatidylinositol binding

ESYT2 MYO1B

1.03e-02316102GO:0035091
GeneOntologyMolecularFunctioncadherin binding

ESYT2 MYO1B

1.18e-02339102GO:0045296
GeneOntologyMolecularFunctioncytoskeletal protein binding

GBP2 GBP3 MYO1B

1.49e-021099103GO:0008092
GeneOntologyMolecularFunctionenzyme inhibitor activity

GBP2 GBP3

1.90e-02435102GO:0004857
GeneOntologyMolecularFunctionprotein dimerization activity

GBP7 GBP2 GBP3

1.91e-021205103GO:0046983
GeneOntologyMolecularFunctionphospholipid binding

ESYT2 MYO1B

2.92e-02548102GO:0005543
GeneOntologyMolecularFunctionenzyme regulator activity

VPS9D1 GBP2 GBP3

2.94e-021418103GO:0030234
GeneOntologyBiologicalProcesspositive regulation of pyroptotic inflammatory response

GBP7 GBP2 GBP3

4.82e-09993GO:0140639
GeneOntologyBiologicalProcesscytolysis in another organism

GBP7 GBP2 GBP3

4.82e-09993GO:0051715
GeneOntologyBiologicalProcesscytolysis

GBP7 GBP2 GBP3

1.26e-081293GO:0019835
GeneOntologyBiologicalProcessadhesion of symbiont to host

GBP7 GBP2 GBP3

6.52e-082093GO:0044406
GeneOntologyBiologicalProcessdefense response to protozoan

GBP7 GBP2 GBP3

5.21e-073993GO:0042832
GeneOntologyBiologicalProcesscellular response to interferon-beta

GBP7 GBP2 GBP3

6.07e-074193GO:0035458
GeneOntologyBiologicalProcessresponse to protozoan

GBP7 GBP2 GBP3

6.54e-074293GO:0001562
GeneOntologyBiologicalProcesspyroptotic inflammatory response

GBP7 GBP2 GBP3

6.54e-074293GO:0070269
GeneOntologyBiologicalProcessresponse to interferon-beta

GBP7 GBP2 GBP3

9.84e-074893GO:0035456
GeneOntologyBiologicalProcesspositive regulation of AIM2 inflammasome complex assembly

GBP2 GBP3

1.02e-06492GO:0140973
GeneOntologyBiologicalProcessregulation of AIM2 inflammasome complex assembly

GBP2 GBP3

2.54e-06692GO:0140971
GeneOntologyBiologicalProcessAIM2 inflammasome complex assembly

GBP2 GBP3

4.73e-06892GO:0140970
GeneOntologyBiologicalProcesscellular response to type II interferon

GBP7 GBP2 GBP3

1.35e-0511493GO:0071346
GeneOntologyBiologicalProcessdisruption of cell in another organism

GBP7 GBP2 GBP3

1.95e-0512993GO:0141061
GeneOntologyBiologicalProcesskilling of cells of another organism

GBP7 GBP2 GBP3

1.95e-0512993GO:0031640
GeneOntologyBiologicalProcessdisruption of anatomical structure in another organism

GBP7 GBP2 GBP3

2.09e-0513293GO:0141060
GeneOntologyBiologicalProcessresponse to type II interferon

GBP7 GBP2 GBP3

2.55e-0514193GO:0034341
GeneOntologyBiologicalProcessdefense response to Gram-positive bacterium

GBP7 GBP2 GBP3

3.07e-0515093GO:0050830
GeneOntologyBiologicalProcesspositive regulation of inflammasome-mediated signaling pathway

GBP2 GBP3

5.47e-052692GO:0141087
GeneOntologyBiologicalProcesspositive regulation of inflammatory response

GBP7 GBP2 GBP3

6.50e-0519393GO:0050729
GeneOntologyBiologicalProcessbiological process involved in interaction with host

GBP7 GBP2 GBP3

1.07e-0422893GO:0051701
GeneOntologyBiologicalProcessregulation of inflammasome-mediated signaling pathway

GBP2 GBP3

1.89e-044892GO:0141085
GeneOntologyBiologicalProcessinflammasome-mediated signaling pathway

GBP2 GBP3

2.31e-045392GO:0141084
GeneOntologyBiologicalProcesscell killing

GBP7 GBP2 GBP3

2.57e-0430793GO:0001906
GeneOntologyBiologicalProcesscellular response to lipopolysaccharide

GBP7 GBP2 GBP3

2.85e-0431893GO:0071222
GeneOntologyBiologicalProcesscellular response to molecule of bacterial origin

GBP7 GBP2 GBP3

3.23e-0433293GO:0071219
GeneOntologyBiologicalProcessactivation of innate immune response

GBP7 GBP2 GBP3

3.26e-0433393GO:0002218
GeneOntologyBiologicalProcessdefense response to virus

GBP7 GBP2 GBP3

3.52e-0434293GO:0051607
GeneOntologyBiologicalProcessbiological process involved in symbiotic interaction

GBP7 GBP2 GBP3

3.80e-0435193GO:0044403
GeneOntologyBiologicalProcesscellular response to biotic stimulus

GBP7 GBP2 GBP3

4.23e-0436493GO:0071216
GeneOntologyBiologicalProcesspositive regulation of pattern recognition receptor signaling pathway

GBP2 GBP3

5.12e-047992GO:0062208
GeneOntologyBiologicalProcessdefense response to bacterium

GBP7 GBP2 GBP3

5.78e-0440593GO:0042742
GeneOntologyBiologicalProcesspositive regulation of innate immune response

GBP7 GBP2 GBP3

6.43e-0442093GO:0045089
GeneOntologyBiologicalProcessresponse to virus

GBP7 GBP2 GBP3

6.65e-0442593GO:0009615
GeneOntologyBiologicalProcesspositive regulation of response to biotic stimulus

GBP7 GBP2 GBP3

7.91e-0445193GO:0002833
GeneOntologyBiologicalProcessresponse to lipopolysaccharide

GBP7 GBP2 GBP3

8.59e-0446493GO:0032496
GeneOntologyBiologicalProcessresponse to molecule of bacterial origin

GBP7 GBP2 GBP3

1.01e-0349193GO:0002237
GeneOntologyBiologicalProcessregulation of inflammatory response

GBP7 GBP2 GBP3

1.16e-0351593GO:0050727
GeneOntologyBiologicalProcessregulation of innate immune response

GBP7 GBP2 GBP3

1.19e-0351993GO:0045088
GeneOntologyBiologicalProcessregulation of cytoplasmic pattern recognition receptor signaling pathway

GBP2 GBP3

1.36e-0312992GO:0039531
GeneOntologyBiologicalProcesspositive regulation of defense response

GBP7 GBP2 GBP3

1.71e-0358993GO:0031349
GeneOntologyBiologicalProcessactivation of immune response

GBP7 GBP2 GBP3

2.01e-0362393GO:0002253
GeneOntologyBiologicalProcessregulation of response to biotic stimulus

GBP7 GBP2 GBP3

2.20e-0364393GO:0002831
GeneOntologyBiologicalProcesscytoplasmic pattern recognition receptor signaling pathway

GBP2 GBP3

2.85e-0318892GO:0002753
GeneOntologyBiologicalProcessregulation of pattern recognition receptor signaling pathway

GBP2 GBP3

3.00e-0319392GO:0062207
GeneOntologyBiologicalProcesspositive regulation of response to external stimulus

GBP7 GBP2 GBP3

3.26e-0373893GO:0032103
GeneOntologyBiologicalProcesscellular response to lipid

GBP7 GBP2 GBP3

3.39e-0374893GO:0071396
GeneOntologyBiologicalProcesspositive regulation of protein-containing complex assembly

GBP2 GBP3

4.13e-0322792GO:0031334
GeneOntologyBiologicalProcesspositive regulation of immune response

GBP7 GBP2 GBP3

4.78e-0384593GO:0050778
GeneOntologyBiologicalProcessresponse to bacterium

GBP7 GBP2 GBP3

6.00e-0391693GO:0009617
GeneOntologyBiologicalProcesspattern recognition receptor signaling pathway

GBP2 GBP3

6.82e-0329492GO:0002221
GeneOntologyBiologicalProcesscellular response to cytokine stimulus

GBP7 GBP2 GBP3

6.98e-0396793GO:0071345
GeneOntologyBiologicalProcessinnate immune response-activating signaling pathway

GBP2 GBP3

7.65e-0331292GO:0002758
GeneOntologyBiologicalProcessregulation of defense response

GBP7 GBP2 GBP3

7.79e-03100693GO:0031347
GeneOntologyBiologicalProcessinflammatory response

GBP7 GBP2 GBP3

8.61e-03104393GO:0006954
GeneOntologyBiologicalProcessresponse to cytokine

GBP7 GBP2 GBP3

9.55e-03108393GO:0034097
GeneOntologyBiologicalProcessregulation of immune response

GBP7 GBP2 GBP3

9.60e-03108593GO:0050776
GeneOntologyBiologicalProcessinnate immune response

GBP7 GBP2 GBP3

9.77e-03109293GO:0045087
GeneOntologyBiologicalProcessresponse to peptide

GBP7 GBP2 GBP3

9.97e-03110093GO:1901652
GeneOntologyBiologicalProcessresponse to lipid

GBP7 GBP2 GBP3

1.06e-02112693GO:0033993
GeneOntologyBiologicalProcessprotein targeting

GBP2 GBP3

1.08e-0237392GO:0006605
GeneOntologyBiologicalProcessintracellular receptor signaling pathway

GBP2 GBP3

1.33e-0241692GO:0030522
GeneOntologyBiologicalProcesspositive regulation of immune system process

GBP7 GBP2 GBP3

1.39e-02124293GO:0002684
GeneOntologyBiologicalProcessdefense response to symbiont

GBP7 GBP2 GBP3

1.53e-02128693GO:0140546
GeneOntologyBiologicalProcessregulation of response to external stimulus

GBP7 GBP2 GBP3

1.63e-02131693GO:0032101
GeneOntologyBiologicalProcessregulation of protein-containing complex assembly

GBP2 GBP3

1.81e-0248992GO:0043254
GeneOntologyBiologicalProcessdefense response to other organism

GBP7 GBP2 GBP3

1.95e-02140793GO:0098542
GeneOntologyCellularComponenthost intracellular region

GBP7 GBP2 GBP3

1.58e-096103GO:0043656
GeneOntologyCellularComponenthost cell part

GBP7 GBP2 GBP3

1.58e-096103GO:0033643
GeneOntologyCellularComponenthost cell cytoplasm

GBP7 GBP2 GBP3

1.58e-096103GO:0030430
GeneOntologyCellularComponenthost intracellular part

GBP7 GBP2 GBP3

1.58e-096103GO:0033646
GeneOntologyCellularComponentsymbiont-containing vacuole

GBP7 GBP2 GBP3

1.58e-096103GO:0020003
GeneOntologyCellularComponentsymbiont-containing vacuole membrane

GBP7 GBP2 GBP3

1.58e-096103GO:0020005
GeneOntologyCellularComponenthost cell cytoplasm part

GBP7 GBP2 GBP3

1.58e-096103GO:0033655
GeneOntologyCellularComponenthost cellular component

GBP7 GBP2 GBP3

3.58e-0815103GO:0018995
GeneOntologyCellularComponentsymbiont cell surface

GBP2 GBP3

5.76e-068102GO:0106139
GeneOntologyCellularComponentother organism part

GBP2 GBP3

7.40e-069102GO:0044217
GeneOntologyCellularComponentperinuclear region of cytoplasm

GBP7 GBP2 GBP3 MYO1B

6.70e-04934104GO:0048471
GeneOntologyCellularComponentactin cytoskeleton

GBP2 GBP3 MYO1B

2.16e-03576103GO:0015629
GeneOntologyCellularComponentvesicle membrane

GBP7 GBP2 GBP3 MYO1B

2.48e-031325104GO:0012506
MousePhenoincreased susceptibility to parasitic infection induced morbidity/mortality

GBP2 GBP3

2.02e-051192MP:0010750
MousePhenoincreased susceptibility to infection induced morbidity/mortality

GBP7 GBP2 GBP3

1.81e-0418593MP:0009787
MousePhenoincreased heart rate variability

GBP2 GBP3

2.98e-044192MP:0003928
MousePhenoincreased fasting circulating glucose level

GBP2 PDPR GBP3

5.98e-0427893MP:0013279
MousePhenoabnormal susceptibility to infection induced morbidity/mortality

GBP7 GBP2 GBP3

6.04e-0427993MP:0009785
MousePhenoabnormal sinus arrhythmia

GBP2 GBP3

1.08e-037892MP:0004122
MousePhenoincreased susceptibility to parasitic infection

GBP2 GBP3

1.46e-039192MP:0005027
MousePhenoincreased susceptibility to bacterial infection induced morbidity/mortality

GBP7 GBP2

1.84e-0310292MP:0009788
MousePhenoabnormal susceptibility to parasitic infection

GBP2 GBP3

2.74e-0312592MP:0020184
MousePhenoabnormal fasting circulating glucose level

GBP2 PDPR GBP3

2.79e-0347493MP:0013277
MousePhenoincreased susceptibility to infection

GBP7 GBP2 GBP3

3.33e-0350493MP:0002406
MousePhenoprolonged RR interval

GBP2 GBP3

3.38e-0313992MP:0010506
MousePhenoincreased circulating glucose level

GBP2 PDPR GBP3

4.33e-0355393MP:0005559
MousePhenoabnormal RR interval

GBP2 GBP3

4.45e-0316092MP:0010504
DomainGBP_C

GBP7 GBP2 GBP3

1.32e-0810103PF02841
DomainGuanylate-bd_C

GBP7 GBP2 GBP3

1.82e-0811103IPR003191
DomainGuanylate-bd_N

GBP7 GBP2 GBP3

1.82e-0811103IPR015894
DomainGBP

GBP7 GBP2 GBP3

1.82e-0811103PF02263
DomainG_GB1_RHD3

GBP7 GBP2 GBP3

1.82e-0811103PS51715
DomainG_GB1_RHD3_dom

GBP7 GBP2 GBP3

1.82e-0811103IPR030386
DomainP-loop_NTPase

GBP7 GBP2 GBP3 MYO1B

7.11e-04848104IPR027417
Domain-

GBP7 GBP2 GBP3

6.17e-037461033.40.50.300
PathwayREACTOME_INTERFERON_GAMMA_SIGNALING

GBP7 GBP2 GBP3

1.78e-059883M965
PathwayREACTOME_INTERFERON_SIGNALING

GBP7 GBP2 GBP3

3.74e-0427383M983
PathwayREACTOME_CYTOKINE_SIGNALING_IN_IMMUNE_SYSTEM

GBP7 GBP2 GBP3

7.91e-0378983M1060
Pubmed

Essential Role of mGBP7 for Survival of Toxoplasma gondii Infection.

GBP7 GBP2 GBP3

1.71e-10510331964735
Pubmed

In silico genomic analysis of the human and murine guanylate-binding protein (GBP) gene clusters.

GBP7 GBP2 GBP3

9.58e-10810316689661
Pubmed

Caspase-11 activation requires lysis of pathogen-containing vacuoles by IFN-induced GTPases.

GBP7 GBP2 GBP3

1.44e-09910324739961
Pubmed

Guanylate binding proteins promote caspase-11-dependent pyroptosis in response to cytoplasmic LPS.

GBP7 GBP2 GBP3

2.82e-091110324715728
Pubmed

Extensive characterization of IFN-induced GTPases mGBP1 to mGBP10 involved in host defense.

GBP7 GBP2 GBP3

2.82e-091110318025219
Pubmed

Pathogen-selective killing by guanylate-binding proteins as a molecular mechanism leading to inflammasome signaling.

GBP7 GBP2 GBP3

3.76e-091210335906252
Pubmed

A family of IFN-γ-inducible 65-kD GTPases protects against bacterial infection.

GBP7 GBP2 GBP3

1.65e-081910321551061
Pubmed

An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome.

GBP7 GBP2 GBP3

2.27e-082110319158679
Pubmed

Guanylate binding proteins facilitate caspase-11-dependent pyroptosis in response to type 3 secretion system-negative Pseudomonas aeruginosa.

GBP2 GBP3

2.23e-07310230062052
Pubmed

Domain motions, dimerization, and membrane interactions of the murine guanylate binding protein 2.

GBP2 GBP3

2.23e-07310236639389
Pubmed

Subtyping of microsatellite stability colorectal cancer reveals guanylate binding protein 2 (GBP2) as a potential immunotherapeutic target.

GBP2 GBP3

2.23e-07310235383115
Pubmed

The interferon (IFN)-induced GTPase, mGBP-2. Role in IFN-gamma-induced murine fibroblast proliferation.

GBP2 GBP3

2.23e-07310211726669
Pubmed

Murine guanylate binding protein 2 (mGBP2) controls Toxoplasma gondii replication.

GBP2 GBP3

2.23e-07310223248289
Pubmed

GBP3 promotes glioma cell proliferation via SQSTM1/p62-ERK1/2 axis.

GBP7 GBP3

2.23e-07310229128363
Pubmed

GTPase properties of the interferon-induced human guanylate-binding protein 2.

GBP2 GBP3

2.23e-0731028706832
Pubmed

Interferon-induced guanylate-binding proteins lack an N(T)KXD consensus motif and bind GMP in addition to GDP and GTP.

GBP2 GBP3

2.23e-0731021715024
Pubmed

GBP2 inhibits pathological angiogenesis in the retina via the AKT/mTOR/VEGFA axis.

GBP2 GBP3

2.23e-07310238636926
Pubmed

The interferon-induced GTPase, mGBP-2, confers resistance to paclitaxel-induced cytotoxicity without inhibiting multinucleation.

GBP2 GBP3

2.23e-07310216914101
Pubmed

Guanylate-binding protein 2 orchestrates innate immune responses against murine norovirus and is antagonized by the viral protein NS7.

GBP2 GBP3

2.23e-07310232354743
Pubmed

Inhibition of VSV and EMCV replication by the interferon-induced GTPase, mGBP-2: differential requirement for wild-type GTP binding domain.

GBP2 GBP3

2.23e-07310215717119
Pubmed

Role of GTP binding, isoprenylation, and the C-terminal α-helices in the inhibition of cell spreading by the interferon-induced GTPase, mouse guanylate-binding protein-2.

GBP2 GBP3

2.23e-07310220950129
Pubmed

Guanylate binding proteins contained in the murine chromosome 3 are important to control mycobacterial infection.

GBP2 GBP3

2.23e-07310232620042
Pubmed

Two families of GTPases dominate the complex cellular response to IFN-gamma.

GBP2 GBP3

2.23e-0731029862701
Pubmed

[Guanylate-binding protein 2 regulates the maturation of mouse dendritic cells induced by β-glucan].

GBP2 GBP3

2.23e-07310229089068
Pubmed

GBP3 promotes glioblastoma resistance to temozolomide by enhancing DNA damage repair.

GBP7 GBP3

2.23e-07310235780181
Pubmed

Guanylate binding proteins enable rapid activation of canonical and noncanonical inflammasomes in Chlamydia-infected macrophages.

GBP2 GBP3

2.23e-07310226416908
Pubmed

The GTPase activity of murine guanylate-binding protein 2 (mGBP2) controls the intracellular localization and recruitment to the parasitophorous vacuole of Toxoplasma gondii.

GBP2 GBP3

2.23e-07310222730319
Pubmed

Guanylate-binding protein-5 is involved in inflammasome activation by bacterial DNA but only the cooperation of multiple GBPs accounts for control of Brucella abortus infection.

GBP2 GBP3

4.46e-07410238404575
Pubmed

Interferon regulatory factor 1 is required for mouse Gbp gene activation by gamma interferon.

GBP2 GBP3

4.46e-0741027823961
Pubmed

Genomic organization and chromosomal localization of a new member of the murine interferon-induced guanylate-binding protein family.

GBP2 GBP3

4.46e-07410210386861
Pubmed

Dnmt1/Tet2-mediated changes in Cmip methylation regulate the development of nonalcoholic fatty liver disease by controlling the Gbp2-Pparγ-CD36 axis.

GBP2 GBP3

4.46e-07410236609599
Pubmed

The Furin Protease Dependence and Antiviral GBP2 Sensitivity of Murine Leukemia Virus Infection Are Determined by the Amino Acid Sequence at the Envelope Glycoprotein Cleavage Site.

GBP2 GBP3

4.46e-07410239337476
Pubmed

cDNA for the beta 1 subunit of guanyl nucleotide-binding regulatory proteins from mouse adrenal glands.

GBP2 GBP3

4.46e-0741028917111
Pubmed

Intracellular trafficking of guanylate-binding proteins is regulated by heterodimerization in a hierarchical manner.

GBP2 GBP3

7.44e-07510221151871
Pubmed

TCR Affinity Biases Th Cell Differentiation by Regulating CD25, Eef1e1, and Gbp2.

GBP2 GBP3

7.44e-07510230858199
Pubmed

Murine GBP-5, a new member of the murine guanylate-binding protein family, is coordinately regulated with other GBPs in vivo and in vitro.

GBP2 GBP3

7.44e-07510212396730
Pubmed

Unique features of different members of the human guanylate-binding protein family.

GBP2 GBP3

7.44e-07510217266443
Pubmed

Murine GBP-2: a new IFN-gamma-induced member of the GBP family of GTPases isolated from macrophages.

GBP2 GBP3

7.44e-0751029858320
Pubmed

Immunity-related GTPase M (IRGM) proteins influence the localization of guanylate-binding protein 2 (GBP2) by modulating macroautophagy.

GBP2 GBP3

1.12e-06610221757726
Pubmed

Distinct modes of action applied by transcription factors STAT1 and IRF1 to initiate transcription of the IFN-gamma-inducible gbp2 gene.

GBP2 GBP3

1.12e-06610217293456
Pubmed

TRIF signaling is required for caspase-11-dependent immune responses and lethality in sepsis.

GBP2 GBP3

1.56e-06710230587103
Pubmed

The interferon-gamma-induced GTPase, mGBP-2, inhibits tumor necrosis factor alpha (TNF-alpha) induction of matrix metalloproteinase-9 (MMP-9) by inhibiting NF-kappaB and Rac protein.

GBP2 GBP3

1.56e-06710221502320
Pubmed

The interferon-gamma-induced murine guanylate-binding protein-2 inhibits rac activation during cell spreading on fibronectin and after platelet-derived growth factor treatment: role for phosphatidylinositol 3-kinase.

GBP2 GBP3

1.56e-06710220505078
Pubmed

Osteoclast fusion and bone loss are restricted by interferon inducible guanylate binding proteins.

GBP2 GBP3

2.68e-06910233479228
Pubmed

Gβ2 Regulates the Multipolar-Bipolar Transition of Newborn Neurons in the Developing Neocortex.

GBP2 GBP3

3.34e-061010228334111
Pubmed

IRGB10 Liberates Bacterial Ligands for Sensing by the AIM2 and Caspase-11-NLRP3 Inflammasomes.

GBP2 GBP3

4.09e-061110227693356
Pubmed

LPS targets host guanylate-binding proteins to the bacterial outer membrane for non-canonical inflammasome activation.

GBP2 GBP3

4.90e-061210229459437
Pubmed

Mapping of quantitative trait loci determining NK cell-mediated resistance to MHC class I-deficient bone marrow grafts in perforin-deficient mice.

GBP2 GBP3

7.80e-061510217114464
Pubmed

Guanylate-binding proteins promote activation of the AIM2 inflammasome during infection with Francisella novicida.

GBP2 GBP3

7.80e-061510225774716
Pubmed

The transcription factor IRF1 and guanylate-binding proteins target activation of the AIM2 inflammasome by Francisella infection.

GBP2 GBP3

1.01e-051710225774715
Pubmed

The macrophage IRF8/IRF1 regulome is required for protection against infections and is associated with chronic inflammation.

GBP2 GBP3

1.14e-051810227001747
Pubmed

Interferon inducible GBPs restrict Burkholderia thailandensis motility induced cell-cell fusion.

GBP2 GBP3

1.41e-052010232150572
Pubmed

Interferon-γ primes macrophages for pathogen ligand-induced killing via a caspase-8 and mitochondrial cell death pathway.

GBP2 GBP3

2.22e-052510235139355
Pubmed

Synergism of TNF-α and IFN-γ Triggers Inflammatory Cell Death, Tissue Damage, and Mortality in SARS-CoV-2 Infection and Cytokine Shock Syndromes.

GBP2 GBP3

3.01e-052910233278357
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

CIC ESYT2 PDPR MYO1B

1.49e-04104910427880917
InteractionGBP2 interactions

GBP7 GBP2 GBP3

2.15e-0654103int:GBP2
InteractionGBP7 interactions

GBP7 GBP2

6.20e-068102int:GBP7
InteractionGBP3 interactions

GBP2 GBP3

9.95e-0610102int:GBP3
Cytoband1p22.2

GBP7 GBP2 GBP3

2.43e-08281031p22.2
CytobandEnsembl 112 genes in cytogenetic band chr1p22

GBP7 GBP2 GBP3

3.07e-06137103chr1p22
CoexpressionSEKI_INFLAMMATORY_RESPONSE_LPS_UP

GBP7 GBP2 GBP3

4.17e-0687103MM1253
CoexpressionZEMEK_IMMUNE_CHECKPOINT_BLOCKADE_OVARIAN_CANCER_OVERLAP_UP

GBP7 GBP2 GBP3

5.97e-0698103MM460
CoexpressionZEMEK_IMMUNE_CHECKPOINT_BLOCKADE_OVARIAN_CANCER_RENCA_UP

GBP7 GBP2 GBP3

6.34e-06100103MM458
CoexpressionHE_LIM_SUN_FETAL_LUNG_C2_CXCL9_POS_MACROPHAGE_CELL

VPS9D1 GBP2 GBP3

1.27e-05126103M45721
CoexpressionSWEET_LUNG_CANCER_KRAS_DN

GBP7 GBP2 GBP3 MYO1B

1.57e-05444104MM1051
CoexpressionICHIBA_GRAFT_VERSUS_HOST_DISEASE_D7_UP

GBP7 GBP2 GBP3

1.67e-05138103MM1047
CoexpressionTABULA_MURIS_SENIS_LIMB_MUSCLE_ENDOTHELIAL_CELL_AGEING

GBP7 GBP2 GBP3

1.93e-05145103MM3744
CoexpressionTABULA_MURIS_SENIS_LUNG_BRONCHIAL_SMOOTH_MUSCLE_CELL_AGEING

GBP7 GBP2 GBP3

2.41e-05156103MM3763
CoexpressionRUAN_RESPONSE_TO_TNF_UP

GBP2 GBP3

2.74e-0521102MM651
CoexpressionGREENBAUM_E2A_TARGETS_DN

GBP2 GBP3

3.01e-0522102MM635
CoexpressionICHIBA_GRAFT_VERSUS_HOST_DISEASE_35D_UP

GBP7 GBP2 GBP3

3.45e-05176103MM1048
CoexpressionRUAN_RESPONSE_TO_TNF_TROGLITAZONE_UP

GBP2 GBP3

3.91e-0525102MM672
CoexpressionZENG_GU_ICB_CONTROL_METAGENE_14_PRECICTIVE_ICB_RESPONSE

GBP7 GBP2 GBP3

4.90e-05198103MM17083
CoexpressionGSE17974_1.5H_VS_72H_IL4_AND_ANTI_IL12_ACT_CD4_TCELL_DN

NT5C3B GBP2 MYO1B

4.97e-05199103M4248
CoexpressionGSE22140_GERMFREE_VS_SPF_ARTHRITIC_MOUSE_CD4_TCELL_DN

CIC VPS9D1 GBP2

4.97e-05199103M7645
CoexpressionGSE37301_MULTIPOTENT_PROGENITOR_VS_GRAN_MONO_PROGENITOR_DN

NT5C3B GBP7 GBP2

5.05e-05200103M8849
CoexpressionGSE17186_NAIVE_VS_CD21LOW_TRANSITIONAL_BCELL_CORD_BLOOD_UP

NT5C3B GBP7 GBP2

5.05e-05200103M7175
CoexpressionGSE17186_MEMORY_VS_NAIVE_BCELL_UP

ESYT2 GBP7 GBP2

5.05e-05200103M7170
CoexpressionGSE17186_BLOOD_VS_CORD_BLOOD_NAIVE_BCELL_DN

ESYT2 NT5C3B GBP2

5.05e-05200103M7178
CoexpressionHOWARD_MONOCYTE_INACT_MONOV_INFLUENZA_A_INDONESIA_05_2005_H5N1_AGE_18_49YO_1DY_UP

VPS9D1 GBP2 GBP3

7.75e-05231103M40995
CoexpressionGRAESSMANN_RESPONSE_TO_MC_AND_SERUM_DEPRIVATION_UP

GBP7 GBP2 GBP3

8.15e-05235103MM978
CoexpressionMARKEY_RB1_ACUTE_LOF_DN

GBP7 GBP2 GBP3

1.19e-04267103MM1091
CoexpressionSASAI_RESISTANCE_TO_NEOPLASTIC_TRANSFROMATION

GBP2 GBP3

1.72e-0452102MM1118
CoexpressionDELASERNA_MYOD_TARGETS_DN

GBP2 GBP3

2.22e-0459102MM659
CoexpressionMIKKELSEN_NPC_LCP_WITH_H3K4ME3

GBP2 GBP3

2.45e-0462102MM865
CoexpressionHOWARD_NEUTROPHIL_INACT_MONOV_INFLUENZA_A_INDONESIA_05_2005_H5N1_AGE_18_49YO_1DY_UP

VPS9D1 GBP2 GBP3

3.74e-04394103M40996
CoexpressionWUNDER_INFLAMMATORY_RESPONSE_AND_CHOLESTEROL_UP

GBP2 GBP3

4.49e-0484102MM1049
CoexpressionSWEET_LUNG_CANCER_KRAS_DN

GBP7 GBP2 MYO1B

4.57e-04422103M7396
CoexpressionCASTELLANO_NRAS_TARGETS_UP

GBP2 GBP3

4.93e-0488102MM1087
CoexpressionTABULA_MURIS_SENIS_LIMB_MUSCLE_SMOOTH_MUSCLE_CELL_AGEING

GBP7 MYO1B

5.38e-0492102MM3748
CoexpressionCHARAFE_BREAST_CANCER_LUMINAL_VS_BASAL_DN

ESYT2 GBP3 MYO1B

5.77e-04457103M14507
CoexpressionHE_LIM_SUN_FETAL_LUNG_C2_ADC_2_CELL

GBP2 GBP3

6.74e-04103102M45742
CoexpressionICHIBA_GRAFT_VERSUS_HOST_DISEASE_D7_UP

GBP7 GBP2

8.39e-04115102M5487
CoexpressionIWANAGA_CARCINOGENESIS_BY_KRAS_DN

GBP2 GBP3

1.15e-03135102MM753
CoexpressionMIKKELSEN_MEF_LCP_WITH_H3K4ME3

GBP2 GBP3

1.27e-03142102MM840
CoexpressionGRAESSMANN_APOPTOSIS_BY_SERUM_DEPRIVATION_UP

GBP7 GBP2 GBP3

1.37e-03616103MM977
CoexpressionWAKABAYASHI_ADIPOGENESIS_PPARG_BOUND_8D

GBP7 GBP2 PWWP3A

1.57e-03646103M2419
CoexpressionHOWARD_DENDRITIC_CELL_INACT_MONOV_INFLUENZA_A_INDONESIA_05_2005_H5N1_AGE_18_49YO_1DY_UP

GBP2 GBP3

1.59e-03159102M40998
CoexpressionGSE35825_IFNA_VS_IFNG_STIM_MACROPHAGE_UP

GBP2 GBP3

1.67e-03163102M8663
CoexpressionBROWN_MYELOID_CELL_DEVELOPMENT_UP

ESYT2 MYO1B

1.76e-03167102M1430
CoexpressionWAKABAYASHI_ADIPOGENESIS_PPARG_BOUND_8D

GBP7 GBP2 PWWP3A

1.78e-03675103MM1073
CoexpressionGSE7768_OVA_ALONE_VS_OVA_WITH_LPS_IMMUNIZED_MOUSE_WHOLE_SPLEEN_6H_DN

GBP2 GBP3

1.82e-03170102M6852
CoexpressionGSE6259_FLT3L_INDUCED_DEC205_POS_DC_VS_CD8_TCELL_DN

GBP2 GBP3

1.90e-03174102M6769
CoexpressionMIKKELSEN_MCV6_LCP_WITH_H3K4ME3

GBP2 GBP3

1.90e-03174102MM836
CoexpressionGSE37605_FOXP3_FUSION_GFP_VS_IRES_GFP_TREG_C57BL6_DN

GBP3 MYO1B

1.95e-03176102M8790
CoexpressionGSE34156_UNTREATED_VS_6H_NOD2_LIGAND_TREATED_MONOCYTE_DN

GBP2 GBP3

1.97e-03177102M8666
CoexpressionGSE6259_CD4_TCELL_VS_CD8_TCELL_UP

ESYT2 NT5C3B

2.19e-03187102M6738
CoexpressionHE_LIM_SUN_FETAL_LUNG_C0_MID_AIRWAY_SMC_2_CELL

ESYT2 GBP2

2.24e-03189102M45678
CoexpressionGSE3400_UNTREATED_VS_IFNB_TREATED_MEF_DN

VPS9D1 GBP2

2.36e-03194102M6134
CoexpressionGSE2770_IL12_AND_TGFB_VS_IL4_TREATED_ACT_CD4_TCELL_48H_DN

VPS9D1 GBP2

2.41e-03196102M6129
CoexpressionGSE17974_0.5H_VS_72H_IL4_AND_ANTI_IL12_ACT_CD4_TCELL_DN

GBP2 MYO1B

2.41e-03196102M4245
CoexpressionGSE22025_UNTREATED_VS_TGFB1_AND_PROGESTERONE_TREATED_CD4_TCELL_DN

GBP2 MYO1B

2.43e-03197102M8386
CoexpressionGSE24081_CONTROLLER_VS_PROGRESSOR_HIV_SPECIFIC_CD8_TCELL_DN

GBP2 MYO1B

2.43e-03197102M4540
CoexpressionGSE24574_BCL6_HIGH_TFH_VS_TCONV_CD4_TCELL_UP

VPS9D1 MYO1B

2.46e-03198102M8335
CoexpressionGSE360_T_GONDII_VS_M_TUBERCULOSIS_MAC_DN

VPS9D1 GBP2

2.46e-03198102M5259
CoexpressionGSE26488_WT_VS_HDAC7_DELTAP_TG_OT2_THYMOCYTE_WITH_PEPTIDE_INJECTION_DN

GBP2 MYO1B

2.48e-03199102M8197
CoexpressionGSE33162_HDAC3_KO_VS_HDAC3_KO_MACROPHAGE_UP

CIC GBP2

2.48e-03199102M9038
CoexpressionGSE14308_NAIVE_CD4_TCELL_VS_INDUCED_TREG_UP

CIC VPS9D1

2.48e-03199102M3391
CoexpressionGSE14308_TH2_VS_TH17_DN

VPS9D1 PDPR

2.48e-03199102M3363
CoexpressionGSE17186_NAIVE_VS_CD21HIGH_TRANSITIONAL_BCELL_CORD_BLOOD_DN

ESYT2 GBP2

2.48e-03199102M7190
CoexpressionGSE19888_ADENOSINE_A3R_INH_VS_ACT_IN_MAST_CELL_DN

GBP7 GBP2

2.48e-03199102M7341
CoexpressionGSE41978_ID2_KO_VS_BIM_KO_KLRG1_LOW_EFFECTOR_CD8_TCELL_UP

VPS9D1 GBP2

2.48e-03199102M9568
CoexpressionGSE360_L_DONOVANI_VS_M_TUBERCULOSIS_MAC_DN

VPS9D1 GBP2

2.48e-03199102M5242
CoexpressionGSE22140_HEALTHY_VS_ARTHRITIC_MOUSE_CD4_TCELL_UP

CIC GBP2

2.48e-03199102M7650
CoexpressionGSE22196_HEALTHY_VS_OBESE_MOUSE_SKIN_GAMMADELTA_TCELL_UP

VPS9D1 GBP2

2.48e-03199102M7655
CoexpressionGSE22140_GERMFREE_VS_SPF_MOUSE_CD4_TCELL_UP

VPS9D1 GBP2

2.48e-03199102M7652
CoexpressionGSE14350_IL2RB_KO_VS_WT_TREG_UP

GBP7 GBP2

2.48e-03199102M3421
CoexpressionGSE39820_IL1B_IL6_VS_IL1B_IL6_IL23A_TREATED_CD4_TCELL_UP

GBP7 PDPR

2.48e-03199102M5615
CoexpressionGSE17721_POLYIC_VS_CPG_1H_BMDC_UP

VPS9D1 GBP2

2.50e-03200102M3934
CoexpressionGSE38681_WT_VS_LYL1_KO_LYMPHOID_PRIMED_MULTIPOTENT_PROGENITOR_DN

GBP7 GBP2

2.50e-03200102M9020
CoexpressionGSE34006_WT_VS_A2AR_KO_TREG_DN

GBP7 GBP2

2.50e-03200102M9042
CoexpressionGSE36078_UNTREATED_VS_AD5_INF_MOUSE_LUNG_DC_DN

NT5C3B GBP7

2.50e-03200102M9292
CoexpressionGSE36527_CD69_NEG_VS_POS_TREG_CD62L_LOS_KLRG1_NEG_UP

GBP7 GBP2

2.50e-03200102M9030
CoexpressionGSE39864_WT_VS_GATA3_KO_TREG_UP

GBP7 GBP2

2.50e-03200102M9064
CoexpressionGSE17721_CTRL_VS_CPG_8H_BMDC_DN

GBP2 MYO1B

2.50e-03200102M3768
CoexpressionGSE34006_A2AR_KO_VS_A2AR_AGONIST_TREATED_TREG_UP

GBP7 GBP2

2.50e-03200102M9051
CoexpressionGSE36078_WT_VS_IL1R_KO_LUNG_DC_AFTER_AD5_T425A_HEXON_INF_UP

NT5C3B GBP7

2.50e-03200102M9294
CoexpressionGSE26890_CXCR1_NEG_VS_POS_EFFECTOR_CD8_TCELL_UP

GBP7 GBP2

2.50e-03200102M8559
CoexpressionGSE33424_CD161_INT_VS_NEG_CD8_TCELL_UP

GBP7 GBP2

2.50e-03200102M8554
CoexpressionGSE26030_TH1_VS_TH17_DAY5_POST_POLARIZATION_UP

GBP7 GBP2

2.50e-03200102M8564
CoexpressionGSE40666_WT_VS_STAT1_KO_CD8_TCELL_UP

CIC ESYT2

2.50e-03200102M9205
CoexpressionGSE3337_CTRL_VS_4H_IFNG_IN_CD8POS_DC_DN

GBP7 GBP2

2.50e-03200102M5099
CoexpressionGSE3337_CTRL_VS_16H_IFNG_IN_CD8POS_DC_DN

GBP7 GBP2

2.50e-03200102M5101
CoexpressionGSE3039_NKT_CELL_VS_B1_BCELL_DN

PDPR MYO1B

2.50e-03200102M6433
CoexpressionGSE21546_WT_VS_SAP1A_KO_AND_ELK1_KO_DP_THYMOCYTES_UP

ESYT2 GBP7

2.50e-03200102M7529
CoexpressionGSE3039_ALPHABETA_CD8_TCELL_VS_B2_BCELL_DN

ESYT2 MYO1B

2.50e-03200102M6445
CoexpressionGSE19888_ADENOSINE_A3R_INH_PRETREAT_AND_ACT_BY_A3R_VS_TCELL_MEMBRANES_ACT_MAST_CELL_UP

GBP7 GBP2

2.50e-03200102M7320
CoexpressionGSE19888_ADENOSINE_A3R_INH_VS_ACT_WITH_INHIBITOR_PRETREATMENT_IN_MAST_CELL_UP

GBP7 GBP2

2.50e-03200102M7322
CoexpressionGSE19888_ADENOSINE_A3R_INH_VS_TCELL_MEMBRANES_ACT_MAST_CELL_UP

GBP7 GBP2

2.50e-03200102M7324
CoexpressionGSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY7_DN

VPS9D1 GBP2

2.50e-03200102M4638
CoexpressionGSE35685_CD34POS_CD38NEG_VS_CD34POS_CD10POS_BONE_MARROW_DN

GBP7 GBP2

2.50e-03200102M9079
CoexpressionGSE35685_CD34POS_CD10NEG_CD62LPOS_VS_CD34POS_CD10POS_BONE_MARROW_DN

GBP7 GBP2

2.50e-03200102M9081
CoexpressionGSE369_PRE_VS_POST_IL6_INJECTION_IFNG_WT_LIVER_UP

GBP7 GBP2

2.50e-03200102M5979
CoexpressionZENG_GU_ICB_CONTROL_METAGENE_8_PRECICTIVE_ICB_RESPONSE

GBP2 GBP3

2.50e-03200102MM17082
CoexpressionGSE2770_UNTREATED_VS_IL12_TREATED_ACT_CD4_TCELL_6H_UP

GBP7 GBP2

2.50e-03200102M6092
CoexpressionGSE11961_MEMORY_BCELL_DAY7_VS_GERMINAL_CENTER_BCELL_DAY40_UP

GBP7 GBP2

2.50e-03200102M9358
CoexpressionGSE17186_NAIVE_VS_CD21LOW_TRANSITIONAL_BCELL_DN

ESYT2 GBP2

2.50e-03200102M7197
CoexpressionGSE1432_CTRL_VS_IFNG_24H_MICROGLIA_DN

VPS9D1 GBP2

2.50e-03200102M3408
CoexpressionGSE1432_CTRL_VS_IFNG_6H_MICROGLIA_DN

VPS9D1 GBP2

2.50e-03200102M3405
CoexpressionGSE23502_BM_VS_COLON_TUMOR_MYELOID_DERIVED_SUPPRESSOR_CELL_UP

GBP7 GBP2

2.50e-03200102M8087
ToppCellEndothelial-Endothelial-F|Endothelial / shred on cell class and cell subclass (v4)

GBP7 GBP2 GBP3

2.30e-061221032cb8bb63c69aed4d4504b9d97219b8707666f950
ToppCellEndothelial-F|World / shred on cell class and cell subclass (v4)

GBP7 GBP2 GBP3

3.41e-0613910332d3c5d35e6c4205711c3500d736fd108443e6b4
ToppCell356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

ESYT2 GBP7 PDPR

3.79e-0614410357d2846ec26d4490ec11c171af447b17a729437e
ToppCelldroplet-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GBP7 GBP2 GBP3

5.91e-06167103774f3264318b002d0df5d06d41d645366038d0bf
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Endothelial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GBP7 GBP2 GBP3

7.04e-06177103ca5a30b3e7bcfdd8de01ceaf7449735b5cd503af
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Endothelial-endothelial_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GBP7 GBP2 GBP3

7.04e-06177103cd0684b876c2a7d5fe7e2773e8e25bb61ecbc795
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Endothelial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GBP7 GBP2 GBP3

7.04e-06177103f471f7747d6e8db7546899019af9508f48a14f89
ToppCelldroplet-Limb_Muscle-MUSCLE-30m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GBP7 GBP2 GBP3

7.16e-0617810301dafd19de04eff459253eaa9a35debf8f3deedf
ToppCelldroplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l19|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GBP7 GBP2 GBP3

7.65e-06182103840427d1c23d60482c943ff006b14007ed44d247
ToppCelldroplet-Trachea-nan-3m-Endothelial-endothelial_cell|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GBP7 GBP2 GBP3

7.91e-0618410376caad53d55fff5acca27bf190a6de7b27437d9f
ToppCelldroplet-Trachea-nan-3m-Endothelial|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GBP7 GBP2 GBP3

7.91e-06184103fa5c3020e75fdde1363393dea97ebd99f1eae9ff
ToppCelldroplet-Trachea-nan-3m-Endothelial-nan|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GBP7 GBP2 GBP3

7.91e-061841031d63cb75a89c5f3f3b9ebf7fce8cb0fd4a92b645
ToppCelldroplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GBP7 GBP2 GBP3

7.91e-061841031fc1f0a3b4dbb085ebcc3960f67be24a108fe5b9
ToppCelldroplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GBP7 GBP2 GBP3

7.91e-061841032467207aaea307873ab286f89cfc7668a227a694
ToppCelldroplet-Trachea-3m-Endothelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GBP7 GBP2 GBP3

7.91e-06184103ad520ab6bb776b5303df505b7e1afb22484f18a7
ToppCelldroplet-Limb_Muscle-nan-24m-Endothelial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GBP7 GBP2 GBP3

8.30e-061871037abc174a06bf07b5f6efe0a370fbb1c23e0079b3
ToppCelldroplet-Limb_Muscle-nan-24m-Endothelial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GBP7 GBP2 GBP3

8.30e-06187103b0a2e417b4eb9a185033e89c5df3431c11488688
ToppCelldroplet-Limb_Muscle-nan-24m-Endothelial-endothelial_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GBP7 GBP2 GBP3

8.30e-06187103f9863428943b695f26bd680e6fc5aeb38ec3422f
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Endothelial-endothelial_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GBP7 GBP3 MYO1B

8.70e-06190103c8370c922e0cf0e0c36e02e1ed2b4053ad6a8073
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Endothelial-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GBP7 GBP3 MYO1B

8.70e-061901035174f91a880f85bb20806023aa68bd4b8ca24ea5
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Endothelial|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GBP7 GBP3 MYO1B

8.70e-0619010390e494cbfbed33a3a0d29bb7dae83f0c81580bcf
ToppCellLeuk-UTI|World / Disease, Lineage and Cell Type

GBP7 GBP2 GBP3

9.12e-0619310326119a0b5d7684022fd16b8b73a0ef5a7d70f3d1
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)-Club_(nasal)_L.0.2.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GBP7 GBP2 GBP3

1.01e-052001030f6620a5baace704518d42fa2f3f90751240f7dd
ToppCellprimary_visual_cortex-Non-neuronal-leptomeningeal_cell-VLMC-VLMC_Osr1_Cd74|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GBP2 GBP3

2.88e-041151024c7d78a246f1b44846fb959359515ef185530053
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Granulocytic-Neutrophil-Neu_c6-FGF23|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

VPS9D1 GBP2

4.32e-041411022d2c468783730d81e3cacb0336027ba0ce1e5f4f
ToppCellPND28|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GBP7 GBP2

4.82e-04149102d3a025440c8ad284a9291c902403e5888d28e90b
ToppCell356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

GBP7 PDPR

4.88e-04150102b6f1fc62d08199fed6156c7cd32f66d9926531b5
ToppCellMyeloid-F|World / shred on cell class and cell subclass (v4)

GBP7 GBP2

5.14e-041541026d53eec4aefe54836bbfd314f28f5e9a24c2d833
ToppCellPND01-03-samps-Endothelial-Postnatal_endothelial-endothelial_cells_C|PND01-03-samps / Age Group, Lineage, Cell class and subclass

GBP7 GBP3

5.28e-041561026c8f442ed94ae31e6832b68137e98ae78091ac6c
ToppCellMyeloid-Myeloid-F|Myeloid / shred on cell class and cell subclass (v4)

GBP7 GBP2

5.28e-04156102d6317843ae5c5749452889e768c187a9d9e8c7fe
ToppCellHealthy/Control-RBC|Healthy/Control / Disease group and Cell class

GBP7 MYO1B

5.41e-041581021fec4f9affdbfba2e281183b717d4d357d474400
ToppCellHealthy/Control-RBC|World / Disease group and Cell class

GBP7 MYO1B

5.55e-04160102f10871238e7bdf3e1f65a17070000477196e50fe
ToppCellprimary_visual_cortex-Non-neuronal-endothelial_cell-Endo-Endo_Ctla2a|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GBP2 GBP3

5.62e-04161102a60ef3f390f56bb05b687b17986fe6382f69f260
ToppCellE16.5-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_G2M|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GBP7 GBP3

5.62e-041611025a8698790f9aba796dd2b64af419055c60bd7de8
ToppCellprimary_visual_cortex-Non-neuronal-endothelial_cell|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GBP2 GBP3

5.69e-041621025799a602ef8d83925907e8e34532428be7330228
ToppCellprimary_visual_cortex-Non-neuronal-endothelial_cell-Endo|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GBP2 GBP3

5.69e-041621020bdb1e5ba33e162bec1acb28256c1405a7658ee5
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage-macrophage,_alveolar-Macro_c2-CCL3L1|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

GBP2 GBP3

5.76e-04163102130c84bca3f72ab7d1a4fee2990c3d01600318ed
ToppCellfrontal_cortex-Non-neuronal-endothelial_cell-Endo|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GBP2 GBP3

5.83e-04164102ec68954fc09b6850273b5e59caa6b09d02151097
ToppCellfrontal_cortex-Non-neuronal-endothelial_cell|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GBP2 GBP3

5.83e-041641026a41a159134e605b80d5e731f9ed5bc803bb531b
ToppCellfrontal_cortex-Non-neuronal-endothelial_cell-Endo-Endo_Ctla2a|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GBP2 GBP3

5.97e-0416610227af6c906cff1d40d134f0386db7708869691121
ToppCellfacs-Thymus-Thymus_Flowthrough-18m-Lymphocytic-DN4_thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GBP7 GBP2

6.04e-04167102d72b08b3cbc34b30a11dcf512e472b64d1606ec1
ToppCellfacs-Thymus-Thymus_Flowthrough-18m-Lymphocytic-DN4_thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GBP7 GBP2

6.04e-0416710222f7384ff2044898d7b0b01cb9d9a3cbaa93a9a3
ToppCellLymphoid-Lymphoid-T_cells_(Cd8+_T_cell)|Lymphoid / shred on cell class and cell subclass (v4)

GBP7 GBP3

6.26e-0417010220fd1a312c81c1bf3c5d2d6caf9b578e6b7a4171
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Myeloid-Granulocytic-Neutrophil-Neu_c5-GSTP1(high)OASL(low)|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

PWWP3A GBP3

6.26e-0417010207b561cd9c528bc8444c9385e1de621eee7b697e
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Granulocytic|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

VPS9D1 GBP2

6.33e-041711022b7c5a557c4bc5c573211c4d618bdd6766a24916
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Granulocytic-Neutrophil|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

VPS9D1 GBP2

6.33e-04171102dcb15bc54aeea06ef8f07f1134f3ff1e21ac0e4f
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c12-FOXP3|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

GBP2 MYO1B

6.41e-04172102eee45759284baa3ed77da6a5fbcc4f8f6c553106
ToppCelldroplet-Marrow-nan-24m-Hematologic-erythroid_progenitor|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GBP2 GBP3

6.41e-04172102910ec7794ea4000db4ef1e2c34e08dbc0243df2c
ToppCellfacs-Spleen-nan-24m-Lymphocytic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GBP7 GBP2

6.48e-04173102e07e126e9dac6f1160cb3191d2e8374f39155d0d
ToppCelldroplet-Marrow-BM-30m-Myeloid-monocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GBP2 GBP3

6.56e-04174102118ba2729ecc6aa1bb8548f3cf537b3f9e902ef0
ToppCelldroplet-Lung-21m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l21|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ESYT2 PDPR

6.71e-0417610291ad2c34144f72283ca112fd3b3784f2f6259f65
ToppCellT_cells-ISG-high_CD4+_T_cells|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis

GBP2 GBP3

6.94e-04179102af35ef8a7768cee0c2af0590e5bec35cee6a4714
ToppCellfacs-Bladder-nan-24m-Epithelial-bladder_mesenchymal_cell_(Car3+)|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GBP7 GBP2

7.01e-0418010212537d8a569faa69f474284d2c201475722b8ca1
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GBP7 GBP3

7.17e-04182102ef65b095f4240d61cfd4a59aec19d72d324dba1d
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GBP7 GBP3

7.17e-0418210297a805783a1f2b055c21307db250e3688674eff3
ToppCellSmart-seq2-lymph_node_(Smart-seq2)-lymphocytic-innate_lymphocytic-innate_lymphoid_cell|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ESYT2 MYO1B

7.17e-04182102b86690c109cdc16844a6cd2216c1bf2bf28efd45
ToppCellwk_15-18-Mesenchymal-Myofibro_&_SMC-Early_airway_SMC_2|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

ESYT2 GBP2

7.25e-04183102a1d4f25e13f5b9e92a9ca0a804a7bed5df8fb2fe
ToppCellCalu_3-infected|Calu_3 / Cell line, Condition and Strain

GBP2 GBP3

7.25e-041831028f7f5000645f24f20a8d7700c4df1f8953a1780b
ToppCellLPS-IL1RA|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GBP7 GBP3

7.33e-04184102c066c2ec4f0f1d6eb183fca5c7bb0cd45c9950dc
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ESYT2 MYO1B

7.41e-04185102a0a629e5d2b65f670ea907bd3f5e3caf17687d8f
ToppCellsaliva-Severe-critical_progression_d28-40-Myeloid-Macrophage-macrophage,_alveolar-Macro_c2-CCL3L1|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

GBP2 GBP3

7.41e-04185102f30fb9d75cdb757b206312992aaf7485bc900f96
ToppCell10x3'2.3-week_14-16-Myeloid_macrophage-stroma-osteoclast|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

GBP2 MYO1B

7.41e-041851025ed49b6d8214c6119355a6d3ee4e25d40bcc0c53
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Endothelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GBP7 GBP3

7.48e-0418610265e25a9dcef5fc71510aaf170e220deef5b2feb2
ToppCelltumor_Lymph_Node_/_Brain-Fibroblasts-Undetermined|Fibroblasts / Location, Cell class and cell subclass

NT5C3B GBP3

7.48e-04186102403ac98f72a42721f84fbd7826f251a88ae534a2
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Endothelial-Endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GBP7 GBP3

7.48e-04186102ba6ba75218efc26371cea24ddbb0e9b3e3f421ac
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Endothelial-endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GBP7 GBP3

7.48e-04186102e4f1259725160719e5fd13d76e5a707efed70013
ToppCell10x5'v1-week_12-13-Myeloid_macrophage-stroma-osteoclast|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

GBP2 MYO1B

7.48e-04186102c9dfcf7bba7e5ef97ad5d9b7084fba932c91ab68
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Activated_Alv_Cap|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GBP7 GBP3

7.56e-04187102f3397dbc23b6c2f24e2c1ba887d8f9aef3ee01a1
ToppCellT_cells-ISG-high_CD4+_T_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

GBP2 GBP3

7.65e-041881026f8946d4710f6e32c937213f99b790b098b8819c
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Endothelial-Endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ESYT2 GBP7

7.65e-04188102d577b3c2a844e3062c7ca9e9ebc1722d0ac95caa
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Endothelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ESYT2 GBP7

7.65e-041881021e788b60dd643bf220d8dfafa82d85fd083cbc71
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Endothelial-endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ESYT2 GBP7

7.65e-041881024dc89c7843ebd078e3414e835c56f11fa27f0c5f
ToppCellEntopeduncular-Endothelial|Entopeduncular / BrainAtlas - Mouse McCarroll V32

GBP2 MYO1B

7.65e-0418810294774652fd42bad5012356672ffac8b6d2c22d37
ToppCelldroplet-Kidney-nan-18m-Endothelial-fenestrated_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GBP7 GBP2

7.73e-0418910291261fe86f0d54b9697f85bb4d3ebdc8975b1bfa
ToppCelldroplet-Kidney-nan-18m-Endothelial-Pecam____fenestrated_capillary_endothelial|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GBP7 GBP2

7.73e-0418910288c0dda28f072368c0df30fc82ee3af9c7670f6c
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_capilar-C|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PWWP3A MYO1B

7.73e-04189102f44ddb6cdbb406b0528a9b0ba3811183ab6d1fc6
ToppCellSubstantia_nigra-Endothelial|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

GBP2 MYO1B

7.73e-04189102bef8234bd9c4d6e3cdef0791d8066b39ba56ebba
ToppCelltumor_Lymph_Node_/_Brain-Fibroblasts-Pericytes|Fibroblasts / Location, Cell class and cell subclass

PDPR MYO1B

7.73e-04189102f4865b7db16de15120504147a8016ac522ad242a
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ESYT2 MYO1B

7.73e-04189102fc88c51ace7d883c01617f3f9b5fab70cc91cc09
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GBP7 GBP2

7.81e-041901022245f61ae0a720db21e29fcd4e910cf590d2655d
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GBP7 GBP2

7.81e-041901026847afca73e1b76c2e86187ccb1a164aefd8f17b
ToppCellfacs-Marrow-KLS-18m-Hematologic-MPP_Fraction_A_+_HSC|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GBP7 GBP2

7.81e-0419010296a9756cad5468a12591021e6d661ed269b5b3d9
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ESYT2 MYO1B

7.89e-0419110265083daf317f66556dc047eb19297dcbe9c70299
ToppCell10x5'v1-week_12-13-Myeloid_macrophage-stroma|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

GBP2 MYO1B

7.89e-041911024cebaf31d4f09f4ab273a819ad5cbff7d9a9b341
ToppCellLPS_only-Endothelial-Endothelial-Activated_Alv_Cap|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GBP7 GBP3

7.89e-04191102a7b18bcf27c38ad2353c239ecb309c80f3ef3359
ToppCellCalu_3-infected-SARSCoV2|infected / Cell line, Condition and Strain

GBP2 GBP3

7.89e-041911022da876d26f37a00dbdf1ee79d724306e8b20f304
ToppCell10x5'v1-week_12-13-Myeloid_macrophage|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

GBP2 MYO1B

7.89e-04191102be2fe2583bdcee0b35c43a347da9c4adb93e30e0
ToppCell3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_general_capillary-EC_general_capillary_L.2.0.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GBP7 GBP2

7.97e-041921026c089bde63dd5f16a07c5929fb49df600f0b21ab
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Endothelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ESYT2 GBP3

7.97e-0419210271b0bfee0461ff64cef35881db3959c517e9731b
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Endothelial-Endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ESYT2 GBP3

7.97e-041921029d53b42cdb537b30233cdfdc08052c8b13a1113f
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Endothelial-endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ESYT2 GBP3

7.97e-04192102042391162df2e3d0027688dd14163c4c6821afe0
ToppCellPND28-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GBP7 GBP2

8.05e-04193102ce5c3ab79900aa6f394c894267340167009c6149
ToppCellPND28-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GBP7 GBP2

8.05e-04193102634fdd157cd1efeebf6ecc810bc45e138331451a
ToppCellNS-critical-d_0-4-Lymphoid-NK|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

NT5C3B MYO1B

8.05e-041931021b29525c5936d1b779253b8c20f059fa091c6127
ToppCellCOVID-19-Myeloid-TRAM2|Myeloid / Condition, Lineage and Cell class

GBP7 GBP3

8.14e-041941024060a60c0271e7397b07993a1ef47b3291bba6e3
ToppCellB_cells-ISG-high_B_cells|B_cells / Immune cells in Kidney/Urine in Lupus Nephritis

GBP2 GBP3

8.22e-04195102b64d9e1a8834401b4dc501566546647754ae21fc
ToppCell10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-SMC_COL-D|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PWWP3A MYO1B

8.22e-0419510278cfde21dde4b877fc76c8b0d5ddaabe44b912d7
ToppCellCerebellum-Endothelial|Cerebellum / BrainAtlas - Mouse McCarroll V32

GBP2 MYO1B

8.22e-041951022192fd9b4682054776f0716933aed5a4a9412657
ToppCellmild-Myeloid-Neutrophils_2|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

GBP2 GBP3

8.30e-04196102ded44b38ea489946e9eedfe752b5a9fde9149c16
ToppCellmild-dn_T|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

ESYT2 GBP2

8.39e-0419710207a1f59c83b748825e0708cd1cc7b63a2cb856cc
DrugAR18

GBP7 GBP2

1.74e-065102CID000114011
Drug6-chloro-6-deoxymannose

GBP7 GBP2

6.24e-069102CID000021090
DrugDNFB

CIC GBP7 GBP2

1.12e-05105103CID000006264
DrugBendroflumethiazide [73-48-3]; Up 200; 9.4uM; PC3; HT_HG-U133A

CIC VPS9D1 GBP2

7.32e-051971034315_UP
DrugPiperine [94-62-2]; Up 200; 14uM; PC3; HT_HG-U133A

VPS9D1 GBP2 MYO1B

7.54e-051991034247_UP
DrugEpiandrosterone [481-29-8]; Down 200; 13.8uM; MCF7; HT_HG-U133A

CIC GBP2 MYO1B

7.66e-052001035687_DN
Drugzaleplon

GBP7 GBP2

1.28e-0439102CID000005719
Drugzopiclone

GBP7 GBP2

1.34e-0440102CID000005735
Drugzolpidem

GBP7 GBP2

1.55e-0443102CID000005732
Drugaluminum fluoride

NT5C3B GBP7 GBP2

1.82e-04268103CID000002124
DrugTDGA

GBP7 GBP2

1.86e-0447102CID000031277
Drugbeta-hydroxy simvastatin acid

GBP2 GBP3

5.12e-0478102ctd:C483161
Drugdidox

GBP7 GBP2

5.80e-0483102CID000003045
DrugAC1L22RD

GBP7 GBP2

6.96e-0491102CID000065183
DrugAC1L1D7P

GBP7 GBP2

9.61e-04107102CID000027435
Drugradicicol, diheterospora chlamydosporia; Up 200; 0.1uM; HL60; HT_HG-U133A

VPS9D1 PWWP3A

2.60e-031771022679_UP
DrugFenoterol hydrobromide [1944-12-3]; Up 200; 10.4uM; HL60; HT_HG-U133A

GBP2 MYO1B

2.71e-031811022378_UP
DrugCiclopirox ethanolamine [41621-49-2]; Down 200; 15uM; MCF7; HT_HG-U133A

CIC PWWP3A

2.74e-031821023317_DN
DrugMetergoline [17692-51-2]; Up 200; 10uM; MCF7; HT_HG-U133A

CIC VPS9D1

2.77e-031831023221_UP
DrugClomiphene citrate (Z,E) [50-41-9]; Up 200; 6.6uM; MCF7; HT_HG-U133A

VPS9D1 MYO1B

2.80e-031841024994_UP
Drugretinoic acid; Up 200; 1uM; MCF7; HT_HG-U133A

VPS9D1 MYO1B

2.83e-031851026971_UP
Drugtrifluoperazine dihydrochloride; Up 200; 10uM; HL60; HT_HG-U133A

VPS9D1 GBP2

2.86e-031861022684_UP
DrugFelodipine [72509-76-3]; Up 200; 10.4uM; MCF7; HT_HG-U133A

CIC VPS9D1

2.89e-031871025294_UP
DrugTrichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HT_HG-U133A

VPS9D1 MYO1B

2.92e-031881026143_UP
DrugMepenzolate bromide [76-90-4]; Down 200; 9.6uM; MCF7; HT_HG-U133A

VPS9D1 GBP2

3.01e-031911026024_DN
Drughaloperidol; Down 200; 10uM; MCF7; HT_HG-U133A

CIC GBP2

3.01e-031911025200_DN
DrugCeforanide [60925-61-3]; Down 200; 7.6uM; MCF7; HT_HG-U133A

CIC PWWP3A

3.01e-031911025351_DN
Drugdaunorubicin HCl; Down 200; 1uM; MCF7; HT_HG-U133A

GBP2 PWWP3A

3.01e-031911027507_DN
DrugPrednisolone [50-24-8]; Up 200; 11uM; HL60; HT_HG-U133A

GBP2 MYO1B

3.01e-031911022393_UP
DrugIsoquinoline, 6,7-dimethoxy-1-methyl-1,2,3,4-tetrahydro, hydrochloride; Up 200; 16.4uM; MCF7; HT_HG-U133A

VPS9D1 MYO1B

3.01e-031911022824_UP
DrugGW8510; Up 200; 10uM; MCF7; HT_HG-U133A

VPS9D1 GBP2

3.04e-031921027062_UP
DrugDextromethorphan hydrobromide monohydrate [6700-34-1]; Down 200; 10.8uM; MCF7; HT_HG-U133A

CIC GBP2

3.04e-031921025401_DN
Drugtrifluoperazine dihydrochloride; Up 200; 10uM; HL60; HT_HG-U133A

GBP2 MYO1B

3.04e-031921021165_UP
Drugwortmannin; Down 200; 1uM; MCF7; HT_HG-U133A_EA

CIC PWWP3A

3.04e-03192102977_DN
DrugICI 182,780; Up 200; 0.01uM; MCF7; HT_HG-U133A_EA

CIC PWWP3A

3.04e-031921021076_UP
DrugRapamycin; Up 200; 0.1uM; PC3; HT_HG-U133A

CIC VPS9D1

3.08e-031931024466_UP
DrugPodophyllotoxin [518-28-5]; Up 200; 9.6uM; MCF7; HT_HG-U133A

GBP2 MYO1B

3.08e-031931026103_UP
DrugLY 294002; Up 200; 10uM; MCF7; HT_HG-U133A

VPS9D1 MYO1B

3.08e-031931021652_UP
DrugCaptopril [62571-86-2]; Up 200; 17.2uM; HL60; HG-U133A

CIC PWWP3A

3.08e-031931021988_UP
Drugradicicol; Up 200; 0.1uM; HL60; HG-U133A

PWWP3A MYO1B

3.08e-03193102544_UP
DrugRapamycin; Down 200; 0.1uM; MCF7; HT_HG-U133A

CIC PWWP3A

3.08e-031931021667_DN
DrugDiethylstilbestrol [56-53-1]; Up 200; 15uM; MCF7; HT_HG-U133A

VPS9D1 GBP2

3.08e-031931023429_UP
Druggenistein; Up 200; 10uM; MCF7; HT_HG-U133A_EA

CIC PWWP3A

3.11e-031941021073_UP
DrugEquilin [474-86-2]; Down 200; 15uM; MCF7; HT_HG-U133A

VPS9D1 MYO1B

3.11e-031941023377_DN
Drug0317956-0000 [391210-11-0]; Down 200; 1uM; MCF7; HT_HG-U133A

CIC VPS9D1

3.11e-031941023969_DN
DrugMebeverine hydrochloride [2753-45-9]; Down 200; 8.6uM; MCF7; HT_HG-U133A

GBP2 MYO1B

3.11e-031941023193_DN
DrugICI 182,780; Up 200; 0.01uM; MCF7; HT_HG-U133A

CIC VPS9D1

3.11e-031941025235_UP
DrugBromperidol [10457-90-6]; Down 200; 9.6uM; MCF7; HT_HG-U133A

CIC PWWP3A

3.11e-031941027457_DN
DrugZalcitabine [7481-89-2]; Up 200; 19uM; MCF7; HT_HG-U133A

CIC VPS9D1

3.11e-031941027352_UP
DrugFlunisolide [3385-03-3]; Down 200; 9.2uM; MCF7; HT_HG-U133A

CIC MYO1B

3.11e-031941023828_DN
DrugMemantine Hydrochloride [41100-52-1]; Down 200; 18.6uM; MCF7; HT_HG-U133A

CIC GBP2

3.11e-031941027354_DN
DrugCyclosporin A [59865-13-3]; Down 200; 3.4uM; MCF7; HT_HG-U133A

CIC MYO1B

3.11e-031941024411_DN
DrugH-89, Dihydrochloride; Up 200; 0.5uM; MCF7; HT_HG-U133A

PWWP3A MYO1B

3.11e-031941026878_UP
DrugPodophyllotoxin [518-28-5]; Down 200; 9.6uM; MCF7; HT_HG-U133A

VPS9D1 PWWP3A

3.14e-031951027198_DN
DrugFenbufen [36330-85-5]; Down 200; 15.8uM; MCF7; HT_HG-U133A

VPS9D1 GBP2

3.14e-031951022308_DN
Drug2-propylpentanoic acid; Down 200; 200uM; PC3; HT_HG-U133A

PWWP3A MYO1B

3.14e-031951021214_DN
Drug5140203; Down 200; 15uM; MCF7; HT_HG-U133A_EA

CIC PWWP3A

3.14e-03195102908_DN
DrugPaclitaxel [33069-62-4]; Up 200; 4.6uM; MCF7; HT_HG-U133A

PWWP3A MYO1B

3.14e-031951021542_UP
DrugCholecalciferol [67-97-0]; Down 200; 10.4uM; HL60; HT_HG-U133A

CIC MYO1B

3.17e-031961022436_DN
DrugAscorbic acid [50-81-7]; Up 200; 22.4uM; MCF7; HT_HG-U133A

VPS9D1 MYO1B

3.17e-031961025407_UP
DrugCarisoprodol [78-44-4]; Down 200; 15.4uM; MCF7; HT_HG-U133A

CIC PWWP3A

3.17e-031961023251_DN
DrugHesperetin [520-33-2]; Down 200; 13.2uM; MCF7; HT_HG-U133A

GBP2 MYO1B

3.17e-031961021531_DN
DrugTiapride hydrochloride [51012-33-0]; Up 200; 11uM; HL60; HT_HG-U133A

GBP2 MYO1B

3.17e-031961022331_UP
DrugGlycocholic acid [475-31-0]; Up 200; 8.6uM; MCF7; HT_HG-U133A

VPS9D1 MYO1B

3.17e-031961023315_UP
DrugBenzonatate [104-31-4]; Down 200; 6.6uM; MCF7; HT_HG-U133A

CIC GBP2

3.17e-031961021679_DN
DrugBAS 012416453; Up 200; 38uM; MCF7; HT_HG-U133A

GBP2 PWWP3A

3.17e-031961026880_UP
DrugQuinethazone [73-49-4]; Up 200; 13.8uM; PC3; HT_HG-U133A

VPS9D1 GBP2

3.17e-031961023793_UP
DrugAminophylline [317-34-0]; Down 200; 9.6uM; MCF7; HT_HG-U133A

VPS9D1 MYO1B

3.17e-031961023374_DN
DrugNetilmicin sulfate [56931-57-2]; Down 200; 2.8uM; HL60; HT_HG-U133A

CIC MYO1B

3.17e-031961022963_DN
DrugPhenethicillin potassium salt [132-93-4]; Down 200; 10uM; MCF7; HT_HG-U133A

VPS9D1 MYO1B

3.20e-031971026105_DN
DrugHexestrol [84-16-2]; Up 200; 14.8uM; PC3; HT_HG-U133A

CIC MYO1B

3.20e-031971025776_UP
DrugOleandomycin phosphate [7060-74-4]; Down 200; 5uM; MCF7; HT_HG-U133A

CIC GBP2

3.20e-031971021518_DN
DrugZaprinast [37762-06-4]; Down 200; 14.8uM; MCF7; HT_HG-U133A

CIC MYO1B

3.20e-031971023226_DN
DrugRaloxifene hydrochloride [82640-04-8]; Up 200; 7.8uM; PC3; HT_HG-U133A

CIC VPS9D1

3.20e-031971025759_UP
DrugIsoniazid [54-85-3]; Down 200; 29.2uM; MCF7; HT_HG-U133A

CIC VPS9D1

3.20e-031971027197_DN
DrugCapsaicin [404-86-4]; Down 200; 13uM; MCF7; HT_HG-U133A

VPS9D1 GBP2

3.20e-031971023372_DN
DrugLincomycin hydrochloride [859-18-7]; Up 200; 9uM; HL60; HT_HG-U133A

VPS9D1 MYO1B

3.20e-031971022380_UP
DrugDapsone [80-08-0]; Down 200; 16.2uM; MCF7; HT_HG-U133A

CIC GBP2

3.20e-031971021705_DN
DrugCefixime [79350-37-1]; Up 200; 8.8uM; MCF7; HT_HG-U133A

CIC VPS9D1

3.20e-031971023247_UP
DrugCefazolin sodium salt [27164-46-1]; Up 200; 8.4uM; MCF7; HT_HG-U133A

VPS9D1 GBP2

3.20e-031971024708_UP
DrugEquilin [474-86-2]; Down 200; 15uM; HL60; HT_HG-U133A

GBP2 MYO1B

3.20e-031971023039_DN
DrugAlfaxalone [23930-19-0]; Up 200; 12uM; MCF7; HT_HG-U133A

GBP2 MYO1B

3.20e-031971026514_UP
DrugDemecarium bromide [56-94-0]; Down 200; 5.6uM; MCF7; HT_HG-U133A

CIC GBP2

3.20e-031971022773_DN
DrugNorethindrone [68-22-4]; Down 200; 13.4uM; MCF7; HT_HG-U133A

PWWP3A MYO1B

3.20e-031971027414_DN
DrugPhenazopyridine hydrochloride [136-40-3]; Down 200; 16uM; MCF7; HT_HG-U133A

VPS9D1 MYO1B

3.20e-031971026100_DN
DrugRoxarsone [121-19-7]; Up 200; 15.2uM; PC3; HT_HG-U133A

GBP2 MYO1B

3.20e-031971025051_UP
DrugCetirizine dihydrochloride [83881-52-1]; Up 200; 8.6uM; HL60; HT_HG-U133A

VPS9D1 MYO1B

3.20e-031971022468_UP
DrugD-cycloserine [68-41-7]; Down 200; 39.2uM; HL60; HT_HG-U133A

CIC MYO1B

3.20e-031971026139_DN
Drugalpha-Santonin [481-06-1]; Down 200; 16.2uM; MCF7; HT_HG-U133A

CIC VPS9D1

3.20e-031971023877_DN
DrugPseudopelletierine hydrochloride [6164-62-1]; Up 200; 21uM; MCF7; HT_HG-U133A

CIC MYO1B

3.20e-031971022766_UP
Drug2-propylpentanoic acid; Up 200; 50uM; HL60; HT_HG-U133A

CIC VPS9D1

3.23e-031981021163_UP
DrugAsiaticoside [16830-15-2]; Down 200; 4.2uM; HL60; HT_HG-U133A

CIC PWWP3A

3.23e-031981022943_DN
DrugErgocryptine-alpha [511-09-1]; Down 200; 7uM; MCF7; HT_HG-U133A

CIC PWWP3A

3.23e-031981023434_DN
Diseaseage at menopause

ESYT2 VPS9D1

3.58e-0330292EFO_0004704
Diseasecarotid artery intima media thickness

PWWP3A GBP3

7.78e-0345092EFO_0007117

Protein segments in the cluster

PeptideGeneStartEntry
EWLNKTVKHMWPFIC

ESYT2

196

A0FGR8
KEKLPHMVEWWTKAH

NT5C3B

96

Q969T7
VHCWAWLKKHMPKDS

PDPR

596

Q8NCN5
VKSHTKGIWMWCVPH

GBP2

71

P32456
VKSHTKGIWMWCVPH

GBP3

71

Q9H0R5
VKSETKGIWMWCVPH

GBP7

71

Q8N8V2
VGMLVWHKHKKYPFW

PWWP3A

411

Q2TAK8
VKEAHFKAHPDWKWC

CIC

256

Q96RK0
EQDHDWPKHWKAKLK

VPS9D1

246

Q9Y2B5
KMLCKQTWPHWKGPA

MYO1B

646

O43795