| Category | Name | IntersectionWithQuery | PValue | GenesInTerm | GenesInQuery | GenesInTermInQuery | ID |
|---|---|---|---|---|---|---|---|
| GeneOntologyMolecularFunction | medium-chain fatty acid omega-hydroxylase activity | 9.80e-06 | 2 | 63 | 2 | GO:0140981 | |
| GeneOntologyMolecularFunction | 16-hydroxypalmitate dehydrogenase activity | 9.80e-06 | 2 | 63 | 2 | GO:0103002 | |
| GeneOntologyMolecularFunction | leukotriene-B4 20-monooxygenase activity | 2.04e-04 | 7 | 63 | 2 | GO:0050051 | |
| GeneOntologyMolecularFunction | alkane 1-monooxygenase activity | 2.04e-04 | 7 | 63 | 2 | GO:0018685 | |
| GeneOntologyMolecularFunction | arachidonate omega-hydroxylase activity | 4.34e-04 | 10 | 63 | 2 | GO:0052869 | |
| GeneOntologyMolecularFunction | fatty acid omega-hydroxylase activity | 4.34e-04 | 10 | 63 | 2 | GO:0120250 | |
| GeneOntologyMolecularFunction | long-chain fatty acid omega-hydroxylase activity | 4.34e-04 | 10 | 63 | 2 | GO:0102033 | |
| GeneOntologyMolecularFunction | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen | 7.47e-04 | 13 | 63 | 2 | GO:0016713 | |
| GeneOntologyMolecularFunction | arachidonate binding | 1.00e-03 | 15 | 63 | 2 | GO:0050544 | |
| GeneOntologyMolecularFunction | icosanoid binding | 1.14e-03 | 16 | 63 | 2 | GO:0050542 | |
| GeneOntologyMolecularFunction | icosatetraenoic acid binding | 1.14e-03 | 16 | 63 | 2 | GO:0050543 | |
| GeneOntologyMolecularFunction | fatty acid binding | 1.35e-03 | 69 | 63 | 3 | GO:0005504 | |
| GeneOntologyMolecularFunction | arachidonate epoxygenase activity | 2.59e-03 | 24 | 63 | 2 | GO:0008392 | |
| GeneOntologyMolecularFunction | arachidonate monooxygenase activity | 3.27e-03 | 27 | 63 | 2 | GO:0008391 | |
| GeneOntologyMolecularFunction | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | 3.29e-03 | 194 | 63 | 4 | GO:0016705 | |
| GeneOntologyMolecularFunction | long-chain fatty acid binding | 3.51e-03 | 28 | 63 | 2 | GO:0036041 | |
| GeneOntologyMolecularFunction | cytokine receptor activity | 3.57e-03 | 97 | 63 | 3 | GO:0004896 | |
| GeneOntologyBiologicalProcess | lauric acid metabolic process | 2.66e-05 | 3 | 62 | 2 | GO:0048252 | |
| HumanPheno | Hypoplasia of the calcaneus | 1.46e-05 | 2 | 20 | 2 | HP:0012789 | |
| Domain | HEMATOPO_REC_L_F3 | 1.04e-04 | 5 | 61 | 2 | PS01354 | |
| Domain | Hematopoietin_rcpt_L_F3_CS | 1.04e-04 | 5 | 61 | 2 | IPR003530 | |
| Pathway | WP_ENTEROCYTE_CHOLESTEROL_METABOLISM | 2.15e-04 | 36 | 46 | 3 | M48067 | |
| Pathway | WP_CHOLESTEROL_BIOSYNTHESIS_WITH_SKELETAL_DYSPLASIAS | 2.16e-04 | 7 | 46 | 2 | M39848 | |
| Pathway | KEGG_FATTY_ACID_METABOLISM | 3.41e-04 | 42 | 46 | 3 | M699 | |
| Pathway | WP_EICOSANOID_METABOLISM_VIA_CYTOCHROME_P450_MONOOXYGENASES_PATHWAY | 3.70e-04 | 9 | 46 | 2 | M39819 | |
| Pathway | REACTOME_SYNTHESIS_OF_16_20_HYDROXYEICOSATETRAENOIC_ACIDS_HETE | 5.62e-04 | 11 | 46 | 2 | MM14863 | |
| Pathway | REACTOME_EICOSANOIDS | 6.73e-04 | 12 | 46 | 2 | M27129 | |
| Pathway | REACTOME_MISCELLANEOUS_SUBSTRATES | 6.73e-04 | 12 | 46 | 2 | M27128 | |
| Pathway | REACTOME_EICOSANOIDS | 6.73e-04 | 12 | 46 | 2 | MM14845 | |
| Pathway | KEGG_MEDICUS_REFERENCE_CHOLESTEROL_BIOSYNTHESIS | 7.94e-04 | 13 | 46 | 2 | M47945 | |
| Pathway | WP_EICOSANOID_METABOLISM_VIA_CYTOCHROME_P450_MONOOXYGENASES | 9.25e-04 | 14 | 46 | 2 | MM15842 | |
| Pathway | REACTOME_FATTY_ACIDS | 1.06e-03 | 15 | 46 | 2 | M27126 | |
| Pathway | KEGG_RETINOL_METABOLISM | 1.18e-03 | 64 | 46 | 3 | M9488 | |
| Pathway | REACTOME_IL_6_TYPE_CYTOKINE_RECEPTOR_LIGAND_INTERACTIONS | 1.21e-03 | 16 | 46 | 2 | MM15323 | |
| Pathway | REACTOME_IL_6_TYPE_CYTOKINE_RECEPTOR_LIGAND_INTERACTIONS | 1.37e-03 | 17 | 46 | 2 | M27612 | |
| Pathway | KEGG_PPAR_SIGNALING_PATHWAY | 1.47e-03 | 69 | 46 | 3 | M13088 | |
| Pathway | REACTOME_MISCELLANEOUS_SUBSTRATES | 1.54e-03 | 18 | 46 | 2 | MM14843 | |
| Pathway | REACTOME_FATTY_ACIDS | 1.54e-03 | 18 | 46 | 2 | MM14841 | |
| Pathway | WP_CHOLESTEROL_SYNTHESIS_DISORDERS | 1.54e-03 | 18 | 46 | 2 | M45528 | |
| Pathway | WP_CHOLESTEROL_METABOLISM | 1.66e-03 | 72 | 46 | 3 | M46457 | |
| Pathway | WP_PPAR_SIGNALING_PATHWAY | 1.72e-03 | 73 | 46 | 3 | MM15995 | |
| Pubmed | 3.44e-06 | 2 | 65 | 2 | 15611369 | ||
| Pubmed | 3.44e-06 | 2 | 65 | 2 | 23825080 | ||
| Pubmed | 3.44e-06 | 2 | 65 | 2 | 16691295 | ||
| Pubmed | 3.44e-06 | 2 | 65 | 2 | 3829886 | ||
| Pubmed | Induction of cytochrome P450 4A14 contributes to angiotensin II-induced renal fibrosis in mice. | 3.44e-06 | 2 | 65 | 2 | 29277328 | |
| Pubmed | 3.44e-06 | 2 | 65 | 2 | 21820496 | ||
| Pubmed | Androgen-sensitive hypertension associates with upregulated vascular CYP4A12-20-HETE synthase. | 3.44e-06 | 2 | 65 | 2 | 23641057 | |
| Pubmed | Renal function and vasomotor activity in mice lacking the Cyp4a14 gene. | 3.44e-06 | 2 | 65 | 2 | 20943934 | |
| Pubmed | 3.44e-06 | 2 | 65 | 2 | 28912346 | ||
| Pubmed | 3.44e-06 | 2 | 65 | 2 | 24413902 | ||
| Pubmed | 3.44e-06 | 2 | 65 | 2 | 2766933 | ||
| Pubmed | 3.44e-06 | 2 | 65 | 2 | 8031839 | ||
| Pubmed | 3.44e-06 | 2 | 65 | 2 | 10860550 | ||
| Pubmed | 3.44e-06 | 2 | 65 | 2 | 17112342 | ||
| Pubmed | Alterations in the regulation of androgen-sensitive Cyp 4a monooxygenases cause hypertension. | 3.44e-06 | 2 | 65 | 2 | 11320253 | |
| Pubmed | 3.44e-06 | 2 | 65 | 2 | 11689484 | ||
| Pubmed | 3.44e-06 | 2 | 65 | 2 | 11689483 | ||
| Pubmed | Characterization of the CYP4A11 gene, a second CYP4A gene in humans. | 3.44e-06 | 2 | 65 | 2 | 12464262 | |
| Pubmed | High-fat diet-induced obesity and insulin resistance in CYP4a14-/- mice is mediated by 20-HETE. | 3.44e-06 | 2 | 65 | 2 | 30088983 | |
| Pubmed | Expression of cytochrome P450 4A mRNA in mouse lung: effect of clofibrate and interleukin-1beta. | 3.44e-06 | 2 | 65 | 2 | 15066132 | |
| Pubmed | Mechanisms of podocyte injury in diabetes: role of cytochrome P450 and NADPH oxidases. | 3.44e-06 | 2 | 65 | 2 | 19208908 | |
| Pubmed | Genetic analysis of resistance to radiation lymphomagenesis with recombinant inbred strains of mice. | 1.03e-05 | 3 | 65 | 2 | 2354437 | |
| Pubmed | 1.03e-05 | 3 | 65 | 2 | 8011168 | ||
| Pubmed | Ablation of cytochrome P450 omega-hydroxylase 4A14 gene attenuates hepatic steatosis and fibrosis. | 1.03e-05 | 3 | 65 | 2 | 28270609 | |
| Pubmed | The P450 superfamily: update on new sequences, gene mapping, and recommended nomenclature. | 1.03e-05 | 3 | 65 | 2 | 1991046 | |
| Pubmed | 1.03e-05 | 3 | 65 | 2 | 19713718 | ||
| Pubmed | 1.03e-05 | 3 | 65 | 2 | 15313227 | ||
| Pubmed | 1.03e-05 | 3 | 65 | 2 | 37659685 | ||
| Pubmed | 1.03e-05 | 3 | 65 | 2 | 9271096 | ||
| Pubmed | 2.06e-05 | 4 | 65 | 2 | 8334987 | ||
| Pubmed | 2.06e-05 | 4 | 65 | 2 | 1552159 | ||
| Pubmed | Altered expression of hepatic CYP2E1 and CYP4A in obese, diabetic ob/ob mice, and fa/fa Zucker rats. | 2.06e-05 | 4 | 65 | 2 | 10049703 | |
| Pubmed | 2.06e-05 | 4 | 65 | 2 | 9384599 | ||
| Pubmed | 2.06e-05 | 4 | 65 | 2 | 22159897 | ||
| Pubmed | 2.06e-05 | 4 | 65 | 2 | 21161333 | ||
| Pubmed | 3.43e-05 | 5 | 65 | 2 | 8363569 | ||
| Pubmed | 3.43e-05 | 5 | 65 | 2 | 20427718 | ||
| Pubmed | Mapping of guanylin to murine chromosome 4 and human chromosome 1p34-p35. | 3.43e-05 | 5 | 65 | 2 | 7601480 | |
| Pubmed | 5.13e-05 | 6 | 65 | 2 | 3166417 | ||
| Pubmed | Peroxisome proliferator-activated receptor-α accelerates α-chlorofatty acid catabolism. | 5.13e-05 | 6 | 65 | 2 | 28007964 | |
| Pubmed | 5.13e-05 | 6 | 65 | 2 | 11461119 | ||
| Pubmed | 5.13e-05 | 6 | 65 | 2 | 8798505 | ||
| Pubmed | Mouse uroporphyrinogen decarboxylase: cDNA cloning, expression, and mapping. | 5.13e-05 | 6 | 65 | 2 | 8661721 | |
| Pubmed | 7.18e-05 | 7 | 65 | 2 | 12958197 | ||
| Pubmed | 7.18e-05 | 7 | 65 | 2 | 18648086 | ||
| Pubmed | 7.18e-05 | 7 | 65 | 2 | 1978328 | ||
| Pubmed | Drug metabolizing enzyme induction pathways in experimental non-alcoholic steatohepatitis. | 9.56e-05 | 8 | 65 | 2 | 18488193 | |
| Pubmed | Microdissection and microcloning of mid-chromosome 4: genetic mapping of 41 microdissection clones. | 9.56e-05 | 8 | 65 | 2 | 8098006 | |
| Pubmed | Mapping genes encoding drug-metabolizing enzymes in recombinant inbred mice. | 1.23e-04 | 9 | 65 | 2 | 1685137 | |
| Pubmed | 1.23e-04 | 9 | 65 | 2 | 7678494 | ||
| Pubmed | 1.53e-04 | 10 | 65 | 2 | 9328433 | ||
| Pubmed | Genetic mapping of meander tail, a mouse mutation affecting cerebellar development. | 1.53e-04 | 10 | 65 | 2 | 2037292 | |
| Pubmed | A dual-activity topoisomerase complex regulates mRNA translation and turnover. | 2.07e-04 | 1105 | 65 | 9 | 35748872 | |
| Pubmed | 2.65e-04 | 13 | 65 | 2 | 32266253 | ||
| Pubmed | Mutations in mice that influence natural killer (NK) cell activity. | 3.08e-04 | 14 | 65 | 2 | 6971254 | |
| Pubmed | 3.56e-04 | 15 | 65 | 2 | 29968852 | ||
| Pubmed | 3.81e-04 | 329 | 65 | 5 | 17474147 | ||
| Pubmed | Exon structure of the nuclear factor I DNA-binding domain from C. elegans to mammals. | 4.06e-04 | 16 | 65 | 2 | 10087299 | |
| Pubmed | 4.06e-04 | 16 | 65 | 2 | 22154759 | ||
| Pubmed | 4.59e-04 | 17 | 65 | 2 | 27197076 | ||
| Pubmed | Expression of murine cyclin B1 mRNAs and genetic mapping of related genomic sequences. | 5.16e-04 | 18 | 65 | 2 | 1387105 | |
| Pubmed | The sequence and analysis of duplication-rich human chromosome 16. | 6.52e-04 | 90 | 65 | 3 | 15616553 | |
| Pubmed | 6.79e-04 | 212 | 65 | 4 | 19521566 | ||
| Pubmed | 9.24e-04 | 24 | 65 | 2 | 7873878 | ||
| Pubmed | Molecular genetic linkage maps of mouse chromosomes 4 and 6. | 1.09e-03 | 26 | 65 | 2 | 1684952 | |
| Pubmed | Intestinal NCoR1, a regulator of epithelial cell maturation, controls neonatal hyperbilirubinemia. | 1.17e-03 | 27 | 65 | 2 | 28167773 | |
| Pubmed | 1.26e-03 | 28 | 65 | 2 | 8944226 | ||
| Pubmed | 1.35e-03 | 29 | 65 | 2 | 28364022 | ||
| Pubmed | 1.36e-03 | 116 | 65 | 3 | 30652415 | ||
| Pubmed | Genome-wide association study of hematological and biochemical traits in a Japanese population. | 1.36e-03 | 116 | 65 | 3 | 20139978 | |
| Pubmed | 1.75e-03 | 33 | 65 | 2 | 32140074 | ||
| Pubmed | Radial glia require PDGFD-PDGFRβ signalling in human but not mouse neocortex. | 1.86e-03 | 34 | 65 | 2 | 25391964 | |
| Cytoband | Ensembl 112 genes in cytogenetic band chr15q26 | 2.15e-04 | 206 | 65 | 4 | chr15q26 | |
| Cytoband | 9p13 | 4.90e-04 | 23 | 65 | 2 | 9p13 | |
| Cytoband | Xp21.1 | 1.08e-03 | 34 | 65 | 2 | Xp21.1 | |
| Cytoband | 1p33 | 1.14e-03 | 35 | 65 | 2 | 1p33 | |
| Cytoband | 15q26.3 | 1.56e-03 | 41 | 65 | 2 | 15q26.3 | |
| Cytoband | 15q26.1 | 2.69e-03 | 54 | 65 | 2 | 15q26.1 | |
| Cytoband | Ensembl 112 genes in cytogenetic band chr1p33 | 3.42e-03 | 61 | 65 | 2 | chr1p33 | |
| GeneFamily | Cytochrome P450 family 4 | 3.78e-03 | 36 | 46 | 2 | 1003 | |
| GeneFamily | Olfactory receptors, family 4 | 4.31e-03 | 129 | 46 | 3 | 151 | |
| GeneFamily | WD repeat domain containing | 4.36e-03 | 262 | 46 | 4 | 362 | |
| Drug | Flunixin meglumine [42461-84-7]; Up 200; 8.2uM; MCF7; HT_HG-U133A | 1.49e-06 | 197 | 65 | 7 | 3411_UP | |
| Drug | Seneciphylline [480-81-9]; Up 200; 12uM; MCF7; HT_HG-U133A | 1.54e-06 | 198 | 65 | 7 | 2797_UP | |
| Disease | X-14939 measurement | 5.87e-05 | 6 | 59 | 2 | EFO_0800747 | |
| Disease | autosomal recessive polycystic kidney disease (biomarker_via_orthology) | 2.14e-04 | 11 | 59 | 2 | DOID:0110861 (biomarker_via_orthology) | |
| Disease | polycystic kidney disease (implicated_via_orthology) | 3.52e-04 | 14 | 59 | 2 | DOID:0080322 (implicated_via_orthology) | |
| Disease | axial length measurement | 5.00e-04 | 77 | 59 | 3 | EFO_0005318 | |
| Disease | sensory perception of bitter taste | 1.24e-03 | 26 | 59 | 2 | GO_0050913 | |
| Disease | transforming growth factor beta measurement | 1.34e-03 | 27 | 59 | 2 | EFO_0004818 | |
| Disease | Mental deterioration | 1.54e-03 | 29 | 59 | 2 | HP_0001268 | |
| Disease | proteinuria (implicated_via_orthology) | 1.65e-03 | 30 | 59 | 2 | DOID:576 (implicated_via_orthology) |
| Peptide | Gene | Start | Entry |
|---|---|---|---|
| CKWYIPLADLVFPSP | 346 | Q12979 | |
| TPAPKSCPERHYWAQ | 21 | P26842 | |
| TFWFLYHKGHPPSEP | 571 | P17405 | |
| TKSHPPCAYTWFLLD | 191 | Q6UY09 | |
| LCRWHPKPYCQALPY | 646 | Q9NWN3 | |
| KALQQFPCPPSHWLF | 46 | Q02928 | |
| QPTPYCKPDHWIHYE | 451 | Q8N865 | |
| VSLFLKDPYSWPAPC | 121 | O75907 | |
| YHWFPIFNPAHPCEL | 621 | P58397 | |
| QLPKPVHKPNRWCFY | 881 | Q9NRL2 | |
| IECWPSNSKYPLPVF | 241 | Q7Z401 | |
| TFLYHPCAHPWLKLQ | 66 | Q8NBR0 | |
| LAWSLPCGFNHILPY | 556 | Q14739 | |
| FCLQKLISLHPFNPW | 151 | Q96K31 | |
| TYPASWPCQPHFLLK | 241 | Q14626 | |
| WPPVQLPYLASLHCS | 371 | Q6P1M3 | |
| HDTDPWATPPYCPKI | 241 | Q0VG99 | |
| LKSDPVAFRPWHCPF | 131 | O43593 | |
| PWFCLSQPVLKPLEY | 1106 | Q9H6A9 | |
| CSAPPPRPVYTNHWA | 61 | P29122 | |
| YVPTCWLLNNCHPTP | 61 | Q9BYR8 | |
| PLPFILKWLSYCQTH | 171 | Q8NGF3 | |
| PCVFIYAWPFPIKSL | 246 | Q8NH21 | |
| KPGKYHFWESCPRPF | 376 | Q8NA70 | |
| SYSPDWPHQPNKTFA | 516 | Q96FE5 | |
| KPSWVLAPAHCYLPN | 46 | A4D1T9 | |
| PCVFIYAWPFPIKSL | 246 | Q8NGA8 | |
| HWPLLVFLLPACLYP | 81 | Q6TCH4 | |
| EAWLSCHPPGKPSLY | 21 | Q9BRP4 | |
| GKLVNHPCPPYALAW | 191 | Q9UG01 | |
| HPCPPYALAWATNSI | 196 | Q9UG01 | |
| HVYPIWLCPFILPSQ | 406 | Q15392 | |
| YRSWNCAPGPFHLFP | 601 | O43909 | |
| ASPTPPYLKWAESLH | 76 | O15169 | |
| KALQQFPCPPSHWLF | 46 | Q5TCH4 | |
| PALCPFHKSPWFPHF | 81 | Q9H8X3 | |
| YPKGFYCSWHLPTPT | 121 | P26992 | |
| LIKYWFHTPPSIPLQ | 276 | P38484 | |
| SPRCWPVSPLCYLYH | 1701 | Q8IWT3 | |
| FNPKCLLPASRHYWT | 181 | P43166 | |
| PKHCPTALSYAWPYA | 866 | Q5TBA9 | |
| YCTCKSLPSPFWQPL | 196 | P56749 | |
| QAIFYAVTPLPWCPH | 1101 | Q9UBN7 | |
| YCPLVPHTMYCLPLW | 361 | Q92902 | |
| FFPKPWSPCLDVEHN | 216 | Q9UK39 | |
| EKWHYLFPAPRDCNP | 141 | Q9H3Y0 | |
| HHPKPEWAEYCLVSP | 1346 | O94851 | |
| PCVFIYAWPFPIKSL | 246 | Q96R69 | |
| LPPYSPVFKSWIHCW | 346 | Q9NZJ7 | |
| PPHCVPDTYSNATLW | 201 | Q9NWD8 | |
| SQHPCFKPWSYIPDG | 91 | Q68DH5 | |
| CVPAFWYNPASPSKD | 766 | Q9UPU3 | |
| PVPIYKPHSICWASV | 321 | Q8NDX1 | |
| HCPYWNTFSLPPYPA | 36 | Q9Y2G9 | |
| YSHPRYKDTPWCSPI | 46 | P78539 | |
| AYWFTHRPKALQPPC | 41 | Q9UKU0 | |
| PLLASRNPCPWHYLH | 101 | Q86UC2 | |
| WKQPDCLPTSYPLDF | 636 | Q70EL4 | |
| TYLYPWILPKPHISS | 956 | Q6ZVD8 | |
| WSLIIPFSCFPKHLP | 326 | Q6ZQN7 | |
| SDSWCPPLPVQTYLH | 1101 | Q9HCK4 | |
| PRPVYPFFDVCWHDK | 446 | Q6ZMU5 | |
| PTNPQAHPYFWQCLK | 1016 | Q9NYK1 | |
| HLLCLNLTQPPYGKW | 1346 | Q9BZ95 | |
| PWKPVFAVSPDHPCF | 571 | Q6P2C0 | |
| HELCWSHTPKPPYYL | 101 | A6NGA9 | |
| PWDTPCPPVYAETKH | 316 | O14746 |