Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionvoltage-gated sodium channel activity

NALCN SCN1A SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A SCN9A SCN10A

3.00e-18268010GO:0005248
GeneOntologyMolecularFunctionsodium channel activity

NALCN SCN1A SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A SCN9A SCN10A

8.22e-15528010GO:0005272
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

SLC6A11 SLC10A2 NALCN SCN1A SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A SCN9A SCN10A SLC29A1

1.61e-131718013GO:0015081
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

CACNA1A SLC6A11 SLC10A2 NALCN SCN1A SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A SCN9A SCN10A PKDREJ SLC29A1 RYR1

3.98e-114658016GO:0046873
GeneOntologyMolecularFunctionmonoatomic cation channel activity

CACNA1A NALCN SCN1A PIEZO1 SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A SCN9A SCN10A PKDREJ RYR1

8.11e-113438014GO:0005261
GeneOntologyMolecularFunctionmonoatomic ion channel activity

CACNA1A NALCN SCN1A PIEZO1 SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A SCN9A SCN10A TMEM150C PKDREJ RYR1

3.56e-104598015GO:0005216
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

CACNA1A SLC6A11 SLC10A2 NALCN SCN1A PIEZO1 SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A SCN9A SCN10A PKDREJ SLC29A1 RYR1

8.74e-106648017GO:0008324
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

CACNA1A SLC6A11 SLC10A2 NALCN SCN1A PIEZO1 SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A SCN9A SCN10A TMEM150C PKDREJ SLC29A1 RYR1

1.75e-097938018GO:0015075
GeneOntologyMolecularFunctionsodium ion binding

SCN1A SCN2A SCN3A SCN8A SCN9A

1.77e-0914805GO:0031402
GeneOntologyMolecularFunctionchannel activity

CACNA1A NALCN SCN1A PIEZO1 SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A SCN9A SCN10A TMEM150C PKDREJ RYR1

2.24e-095258015GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

CACNA1A NALCN SCN1A PIEZO1 SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A SCN9A SCN10A TMEM150C PKDREJ RYR1

2.30e-095268015GO:0022803
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

CACNA1A SLC6A11 SLC10A2 NALCN SCN1A SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A SCN9A SCN10A PKDREJ SLC29A1 RYR1

3.08e-096278016GO:0022890
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

CACNA1A SLC6A11 SLC10A2 NALCN SCN1A SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A SCN9A SCN10A PKDREJ SLC29A1 RYR1 XPR1

6.38e-097588017GO:0015318
GeneOntologyMolecularFunctionalkali metal ion binding

SCN1A SCN2A SCN3A SCN8A SCN9A

5.60e-0826805GO:0031420
GeneOntologyMolecularFunctiontransmembrane transporter activity

CACNA1A SLC6A11 SLC10A2 NALCN SCN1A PIEZO1 SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A SCN9A SCN10A TMEM150C PKDREJ SLC29A1 RYR1 XPR1

1.45e-0711808019GO:0022857
GeneOntologyMolecularFunctiontransporter activity

CACNA1A SLC6A11 SLC10A2 NALCN SCN1A PIEZO1 SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A SCN9A SCN10A TMEM150C PKDREJ SLC29A1 RYR1 XPR1

5.66e-0712898019GO:0005215
GeneOntologyMolecularFunctioncalmodulin binding

CACNA1A SCN2A SCN3A SCN5A CAMSAP3 ADCY3 RYR1

3.82e-05230807GO:0005516
GeneOntologyMolecularFunctionvoltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential

SCN1A SCN2A SCN10A

4.04e-0517803GO:0099508
GeneOntologyMolecularFunctiongated channel activity

CACNA1A SCN1A PIEZO1 SCN2A SCN7A SCN10A TMEM150C RYR1

5.74e-05334808GO:0022836
GeneOntologyMolecularFunctionnitric-oxide synthase binding

SCN5A DNM3 DNM1

9.03e-0522803GO:0050998
GeneOntologyMolecularFunctionprotein serine/threonine kinase binding

DNM3 MAPK8 DNM1

1.18e-0424803GO:0120283
GeneOntologyMolecularFunctionvoltage-gated sodium channel activity involved in cardiac muscle cell action potential

SCN5A SCN10A

2.35e-046802GO:0086006
GeneOntologyMolecularFunctionvoltage-gated monoatomic ion channel activity

CACNA1A SCN1A SCN2A SCN10A RYR1

8.24e-04182805GO:0005244
GeneOntologyMolecularFunctionvoltage-gated channel activity

CACNA1A SCN1A SCN2A SCN10A RYR1

8.65e-04184805GO:0022832
GeneOntologyMolecularFunctionmonocarboxylate:sodium symporter activity

SLC6A11 SLC10A2

1.61e-0315802GO:0140161
GeneOntologyMolecularFunctionmechanosensitive monoatomic ion channel activity

PIEZO1 TMEM150C

2.33e-0318802GO:0008381
GeneOntologyMolecularFunctionsecondary active monocarboxylate transmembrane transporter activity

SLC6A11 SLC10A2

2.59e-0319802GO:0015355
GeneOntologyMolecularFunctionproteasome binding

ECPAS BAG6

2.87e-0320802GO:0070628
GeneOntologyMolecularFunctionheat shock protein binding

TSC2 DNAJA1 BAG6 HTT

4.18e-03163804GO:0031072
GeneOntologyMolecularFunctionsolute:sodium symporter activity

SLC6A11 SLC10A2 SLC29A1

4.22e-0381803GO:0015370
GeneOntologyBiologicalProcesscardiac muscle cell action potential involved in contraction

SCN1A SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A CTNNA3 SCN9A SCN10A

3.45e-14627910GO:0086002
GeneOntologyBiologicalProcessmembrane depolarization during action potential

SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A

8.93e-1336798GO:0086010
GeneOntologyBiologicalProcesscardiac muscle cell action potential

SCN1A SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A CTNNA3 SCN9A SCN10A

1.19e-12877910GO:0086001
GeneOntologyBiologicalProcesscardiac muscle cell contraction

SCN1A SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A CTNNA3 SCN9A SCN10A

2.36e-12937910GO:0086003
GeneOntologyBiologicalProcessactin-mediated cell contraction

SCN1A SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A CTNNA3 SCN9A SCN10A

5.50e-111277910GO:0070252
GeneOntologyBiologicalProcessneuronal action potential

SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A

1.05e-1063798GO:0019228
GeneOntologyBiologicalProcessactin filament-based movement

SCN1A SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A CTNNA3 SCN9A SCN10A

3.49e-101537910GO:0030048
GeneOntologyBiologicalProcesssodium ion transmembrane transport

SLC6A11 NALCN SCN1A SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A SCN9A SCN10A

4.18e-102087911GO:0035725
GeneOntologyBiologicalProcesstransmission of nerve impulse

CACNA1A SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A

4.44e-10112799GO:0019226
GeneOntologyBiologicalProcesssodium ion transport

SLC6A11 SLC10A2 NALCN SCN1A SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A SCN9A SCN10A

5.75e-102757912GO:0006814
GeneOntologyBiologicalProcessstriated muscle contraction

SCN1A SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A CTNNA3 SCN9A SCN10A RYR1

6.55e-102177911GO:0006941
GeneOntologyBiologicalProcesscardiac muscle contraction

SCN1A SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A CTNNA3 SCN9A SCN10A

8.23e-101677910GO:0060048
GeneOntologyBiologicalProcessmembrane depolarization

CACNA1A SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A

8.88e-10121799GO:0051899
GeneOntologyBiologicalProcessaction potential

SCN1A SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A CTNNA3 SCN9A SCN10A

4.96e-092017910GO:0001508
GeneOntologyBiologicalProcessheart contraction

SCN1A SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A CTNNA3 SCN9A MC3R SCN10A

1.80e-082987911GO:0060047
GeneOntologyBiologicalProcessregulation of membrane potential

CACNA1A NALCN SCN1A PIEZO1 SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A CTNNA3 SCN9A SCN10A SLC29A1

2.42e-085597914GO:0042391
GeneOntologyBiologicalProcessheart process

SCN1A SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A CTNNA3 SCN9A MC3R SCN10A

2.61e-083097911GO:0003015
GeneOntologyBiologicalProcessmuscle contraction

SCN1A SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A CTNNA3 SCN9A SCN10A RYR1

3.53e-074007911GO:0006936
GeneOntologyBiologicalProcessmonoatomic cation transmembrane transport

CACNA1A SLC6A11 NALCN SCN1A PIEZO1 SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A SCN9A SCN10A PKDREJ RYR1 HTT

4.54e-079427916GO:0098655
GeneOntologyBiologicalProcessmonoatomic ion transmembrane transport

CACNA1A SLC6A11 NALCN SCN1A PIEZO1 SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A SCN9A SCN10A TMEM150C PKDREJ RYR1 HTT

8.45e-0711157917GO:0034220
GeneOntologyBiologicalProcessmetal ion transport

CACNA1A SLC6A11 SLC10A2 NALCN SCN1A SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A SCN9A SCN10A PKDREJ RYR1 HTT

1.00e-0610007916GO:0030001
GeneOntologyBiologicalProcessinorganic ion transmembrane transport

CACNA1A SLC6A11 NALCN SCN1A SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A SCN9A SCN10A PKDREJ RYR1 HTT XPR1

1.25e-0610177916GO:0098660
GeneOntologyBiologicalProcessmonoatomic cation transport

CACNA1A SLC6A11 SLC10A2 NALCN SCN1A PIEZO1 SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A SCN9A SCN10A PKDREJ RYR1 HTT

1.40e-0611577917GO:0006812
GeneOntologyBiologicalProcessinorganic cation transmembrane transport

CACNA1A SLC6A11 NALCN SCN1A SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A SCN9A SCN10A PKDREJ RYR1 HTT

1.88e-069227915GO:0098662
GeneOntologyBiologicalProcessmonoatomic ion transport

CACNA1A SLC6A11 SLC10A2 NALCN SCN1A PIEZO1 SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A SCN9A SCN10A TMEM150C PKDREJ RYR1 HTT

3.33e-0613747918GO:0006811
GeneOntologyBiologicalProcesscirculatory system process

SCN1A SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A CTNNA3 SCN9A MC3R SCN10A OCLN SLC29A1

3.94e-067337913GO:0003013
GeneOntologyBiologicalProcessresponse to mechanical stimulus

SCN1A PIEZO1 SCN9A SCN10A TMEM150C MAPK8 PKDREJ HTT

4.73e-06247798GO:0009612
GeneOntologyBiologicalProcessblood circulation

SCN1A SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A CTNNA3 SCN9A MC3R SCN10A OCLN

6.24e-066487912GO:0008015
GeneOntologyBiologicalProcessbehavioral response to pain

CACNA1A SCN3A SCN9A SCN10A

6.61e-0632794GO:0048266
GeneOntologyBiologicalProcessmuscle system process

SCN1A SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A CTNNA3 SCN9A SCN10A RYR1

7.30e-065477911GO:0003012
GeneOntologyBiologicalProcessdetection of mechanical stimulus

SCN1A PIEZO1 SCN9A SCN10A PKDREJ

1.01e-0575795GO:0050982
GeneOntologyBiologicalProcessbundle of His cell to Purkinje myocyte communication

SCN5A CTNNA3 SCN10A

2.38e-0515793GO:0086069
GeneOntologyBiologicalProcessresponse to pain

CACNA1A SCN3A SCN9A SCN10A

4.34e-0551794GO:0048265
GeneOntologyBiologicalProcessresponse to abiotic stimulus

UBE4B SCN1A PIEZO1 SCN2A SCN7A SCN9A SCN10A TMEM150C TSC2 MAPK8 DNAJA1 PKDREJ SLC29A1 NLRP3 RYR1 HTT

4.86e-0513617916GO:0009628
GeneOntologyBiologicalProcesspositive regulation of glial cell apoptotic process

CERS6 MAPK8

8.65e-054792GO:0034352
GeneOntologyBiologicalProcessbrain development

CACNA1A BMPR1A GPR158 SCN2A SCN5A FRS2 KDM2B WLS DNAH5 BAG6 HTT CDON

9.89e-058597912GO:0007420
GeneOntologyBiologicalProcesshead development

CACNA1A BMPR1A GPR158 SCN2A SCN5A FRS2 KDM2B WLS DNAH5 BAG6 HTT CDON

1.86e-049197912GO:0060322
GeneOntologyBiologicalProcessbundle of His cell action potential

SCN5A SCN10A

3.00e-047792GO:0086043
GeneOntologyBiologicalProcessbundle of His cell to Purkinje myocyte signaling

SCN5A SCN10A

3.00e-047792GO:0086028
GeneOntologyBiologicalProcessanterior/posterior pattern specification

BMPR1A FRS2 KDM2B WLS HTT CDON

3.72e-04247796GO:0009952
GeneOntologyBiologicalProcessosmosensory signaling pathway

SCN7A NLRP3

4.00e-048792GO:0007231
GeneOntologyBiologicalProcessheart trabecula morphogenesis

BMPR1A UBE4B ADGRG6

4.14e-0438793GO:0061384
GeneOntologyBiologicalProcessdetection of stimulus

OR12D2 OR12D1 OR4C11 SCN1A PIEZO1 SCN9A SCN10A OR52W1 PKDREJ NLRP3

4.23e-047227910GO:0051606
GeneOntologyBiologicalProcessregionalization

BMPR1A FRS2 KDM2B MAPK8 WLS DNAH5 HTT CDON

4.85e-04478798GO:0003002
GeneOntologyBiologicalProcessdetection of external stimulus

SCN1A PIEZO1 SCN9A SCN10A PKDREJ

5.35e-04173795GO:0009581
GeneOntologyBiologicalProcessforebrain development

BMPR1A SCN2A SCN5A FRS2 KDM2B DNAH5 HTT CDON

5.63e-04489798GO:0030900
GeneOntologyBiologicalProcessdetection of abiotic stimulus

SCN1A PIEZO1 SCN9A SCN10A PKDREJ

5.64e-04175795GO:0009582
GeneOntologyBiologicalProcessbehavior

CACNA1A SCN1A SCN2A SCN3A SCN8A SCN9A MC3R SCN10A TSC2 ADCY3 HTT

5.66e-048917911GO:0007610
GeneOntologyBiologicalProcesscentral nervous system development

CACNA1A BMPR1A GPR158 SCN2A SCN5A FRS2 KDM2B CERS6 WLS DNAH5 BAG6 HTT CDON

5.84e-0411977913GO:0007417
GeneOntologyBiologicalProcessdetection of stimulus involved in sensory perception of pain

SCN1A SCN9A SCN10A

5.98e-0443793GO:0062149
GeneOntologyBiologicalProcessregulation of atrial cardiac muscle cell membrane depolarization

SCN5A SCN10A

6.39e-0410792GO:0060371
GeneOntologyBiologicalProcessactin filament-based process

FMNL3 SCN1A SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A CTNNA3 SCN9A SCN10A

6.86e-049127911GO:0030029
GeneOntologyBiologicalProcessacrosome reaction

PKDREJ ZP3 ADCY3

7.77e-0447793GO:0007340
GeneOntologyBiologicalProcesssynaptic vesicle budding from presynaptic endocytic zone membrane

DNM3 DNM1

7.79e-0411792GO:0016185
GeneOntologyBiologicalProcessadenylate cyclase-activating G protein-coupled receptor signaling pathway

PDE4A MC3R ADCY3 ADGRG4 ADGRG6

8.36e-04191795GO:0007189
GeneOntologyBiologicalProcessregulation of striated muscle contraction

SCN4A SCN5A CTNNA3 SCN10A

8.75e-04111794GO:0006942
GeneOntologyBiologicalProcesspattern specification process

BMPR1A FRS2 KDM2B MAPK8 WLS DNAH5 HTT CDON

9.05e-04526798GO:0007389
GeneOntologyBiologicalProcessadult walking behavior

CACNA1A SCN1A SCN8A

9.31e-0450793GO:0007628
GeneOntologyBiologicalProcessAV node cell to bundle of His cell signaling

SCN5A SCN10A

9.32e-0412792GO:0086027
GeneOntologyBiologicalProcessAV node cell action potential

SCN5A SCN10A

9.32e-0412792GO:0086016
GeneOntologyBiologicalProcessresponse to osmotic stress

SCN2A SCN7A NLRP3 RYR1

9.35e-04113794GO:0006970
GeneOntologyBiologicalProcessregulation of muscle contraction

SCN4A SCN5A CTNNA3 SCN10A RYR1

1.07e-03202795GO:0006937
GeneOntologyBiologicalProcessparaxial mesoderm morphogenesis

BMPR1A HTT

1.10e-0313792GO:0048340
GeneOntologyBiologicalProcessdetermination of adult lifespan

SCN1A SCN2A HTT

1.17e-0354793GO:0008340
GeneOntologyBiologicalProcesslateral ventricle development

KDM2B DNAH5

1.28e-0314792GO:0021670
GeneOntologyBiologicalProcesscardiac chamber development

BMPR1A UBE4B SCN5A FRS2 ADGRG6

1.33e-03212795GO:0003205
GeneOntologyBiologicalProcessdetection of mechanical stimulus involved in sensory perception

SCN1A SCN9A SCN10A

1.36e-0357793GO:0050974
GeneOntologyBiologicalProcesstrabecula morphogenesis

BMPR1A UBE4B ADGRG6

1.36e-0357793GO:0061383
GeneOntologyBiologicalProcessmulticellular organismal response to stress

CACNA1A SCN3A SCN9A SCN10A

1.40e-03126794GO:0033555
GeneOntologyBiologicalProcesssynaptic vesicle budding

DNM3 DNM1

1.47e-0315792GO:0070142
GeneOntologyBiologicalProcessAV node cell to bundle of His cell communication

SCN5A SCN10A

1.47e-0315792GO:0086067
GeneOntologyBiologicalProcesslipid droplet formation

RNF213 FITM2

1.47e-0315792GO:0140042
GeneOntologyCellularComponentvoltage-gated sodium channel complex

SCN1A SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A SCN9A SCN10A

2.62e-1817809GO:0001518
GeneOntologyCellularComponentsodium channel complex

SCN1A SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A SCN9A SCN10A

1.04e-1529809GO:0034706
GeneOntologyCellularComponentcation channel complex

CACNA1A SCN1A SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A SCN9A SCN10A RYR1

1.52e-092358011GO:0034703
GeneOntologyCellularComponentmonoatomic ion channel complex

CACNA1A NALCN SCN1A SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A SCN9A SCN10A RYR1

2.05e-083788012GO:0034702
GeneOntologyCellularComponenttransmembrane transporter complex

CACNA1A NALCN SCN1A SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A SCN9A SCN10A RYR1

6.81e-075238012GO:1902495
GeneOntologyCellularComponentpresynaptic membrane

CACNA1A SLC6A11 GPR158 SCN1A SCN2A SCN8A SCN10A LRRC4B DNM1

1.13e-06277809GO:0042734
GeneOntologyCellularComponenttransporter complex

CACNA1A NALCN SCN1A SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A SCN9A SCN10A RYR1

1.16e-065508012GO:1990351
GeneOntologyCellularComponentaxon

SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A DNM3 LRRC4B TSC2 MAPK8 DNM1 HTT

6.47e-068918014GO:0030424
GeneOntologyCellularComponentplasma membrane protein complex

CACNA1A BMPR1A SCN1A SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A SCN9A SCN10A ZAP70 RYR1

8.25e-067858013GO:0098797
GeneOntologyCellularComponentsynaptic membrane

CACNA1A SLC6A11 GPR158 SCN1A SCN2A SCN8A SCN10A DNM3 LRRC4B DNM1 HTT

1.33e-055838011GO:0097060
GeneOntologyCellularComponentnode of Ranvier

SCN1A SCN2A SCN8A

5.87e-0520803GO:0033268
GeneOntologyCellularComponentpresynapse

CACNA1A SLC6A11 GPR158 SCN1A SCN2A SCN8A SCN10A DNM3 LRRC4B DNM1 SLC29A1 HTT

1.32e-048868012GO:0098793
GeneOntologyCellularComponentintercalated disc

SCN1A SCN2A SCN5A CTNNA3

1.34e-0468804GO:0014704
GeneOntologyCellularComponentmembrane protein complex

CACNA1A BMPR1A COPZ1 NALCN SCN1A SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A SCN9A SCN10A DNM1 ZAP70 RYR1

1.50e-0414988016GO:0098796
GeneOntologyCellularComponentaxon initial segment

SCN1A SCN2A SCN8A

1.84e-0429803GO:0043194
GeneOntologyCellularComponentT-tubule

SCN1A SCN2A SCN5A RYR1

2.40e-0479804GO:0030315
GeneOntologyCellularComponentmain axon

SCN1A SCN2A SCN8A DNM1

3.79e-0489804GO:0044304
GeneOntologyCellularComponentcell-cell junction

TMEM204 SCN1A SCN2A SCN5A CAMSAP3 CTNNA3 FRS2 OCLN ZAP70

4.22e-04591809GO:0005911
GeneOntologyCellularComponentcell-cell contact zone

SCN1A SCN2A SCN5A CTNNA3

4.67e-0494804GO:0044291
GeneOntologyCellularComponentZ disc

SCN1A SCN5A SCN8A RYR1

2.70e-03151804GO:0030018
GeneOntologyCellularComponentI band

SCN1A SCN5A SCN8A RYR1

3.80e-03166804GO:0031674
GeneOntologyCellularComponentglutamatergic synapse

CACNA1A SCN2A SCN8A SCN10A DNM3 LRRC4B TSC2 DNM1 HTT

3.95e-03817809GO:0098978
GeneOntologyCellularComponentanchoring junction

FOCAD TMEM204 SCN1A SCN2A SCN5A CAMSAP3 CTNNA3 FRS2 OCLN ZAP70

4.00e-039768010GO:0070161
HumanPhenoImpulsivity

CACNA1A GLDC SCN1A SCN2A SCN3A SCN8A SCN9A TSC2 ACTL6B DNM1 CDON

4.12e-091493711HP:0100710
HumanPhenoComplex febrile seizure

CACNA1A SCN1A SCN2A SCN8A SCN9A

6.30e-0816375HP:0011172
HumanPhenoFocal impaired awareness seizure

CACNA1A SCN1A SCN2A SCN3A SCN8A SCN9A TSC2 DNM1 HTT

1.80e-07126379HP:0002384
HumanPhenoFocal automatism seizure

CACNA1A SCN1A SCN2A SCN8A

1.12e-0612374HP:0032898
HumanPhenoRigidity

CACNA1A SCN1A SCN2A SCN3A SCN8A SCN9A ACTL6B DNM1 RYR1 HTT

1.79e-062143710HP:0002063
HumanPhenoFacial tics

CACNA1A SCN1A SCN2A SCN9A

3.04e-0615374HP:0011468
HumanPhenoAtypical absence status epilepticus

SCN1A SCN2A SCN9A DNM1

5.24e-0617374HP:0011151
HumanPhenoChoking episodes

CACNA1A SCN4A DNM1 HTT

5.24e-0617374HP:0030842
HumanPhenoGeneralized tonic seizure

CACNA1A SCN1A SCN2A SCN8A SCN9A DNM1

5.31e-0664376HP:0010818
HumanPhenoDevelopmental regression

CACNA1A BMPR1A NALCN SCN1A SCN2A SCN3A SCN8A SCN9A ACTL6B DNM1 WLS FITM2 HTT

6.45e-064403713HP:0002376
HumanPhenoGeneralized non-convulsive status epilepticus without coma

SCN1A SCN2A SCN9A DNM1

6.71e-0618374HP:0032860
HumanPhenoAggressive behavior

CACNA1A NALCN UBE4B GLDC SCN1A SCN2A SCN3A SCN8A SCN9A TSC2 ACTL6B DNM1 HTT CDON

6.78e-065163714HP:0000718
HumanPhenoAbnormal aggressive, impulsive or violent behavior

CACNA1A NALCN UBE4B GLDC SCN1A SCN2A SCN3A SCN8A SCN9A TSC2 ACTL6B DNM1 HTT CDON

6.78e-065163714HP:0006919
HumanPhenoNon-convulsive status epilepticus without coma

SCN1A SCN2A SCN9A DNM1

1.05e-0520374HP:0032671
HumanPhenoStatus epilepticus

CACNA1A SCN1A SCN2A SCN3A SCN8A SCN9A TSC2 ACTL6B DNM1

1.17e-05207379HP:0002133
HumanPhenoAtypical absence seizure

CACNA1A SCN1A SCN2A SCN9A DNM1

1.69e-0546375HP:0007270
HumanPhenoEEG with focal epileptiform discharges

CACNA1A SCN1A SCN2A SCN8A SCN9A ACTL6B DNM1

1.73e-05118377HP:0011185
HumanPhenoPhotosensitive myoclonic seizure

SCN1A SCN2A SCN9A

1.93e-058373HP:0001327
HumanPhenoCyanotic episode

SCN1A SCN2A SCN9A

1.93e-058373HP:0200048
HumanPhenoClonic seizure

SCN1A SCN2A SCN3A SCN8A SCN9A DNM1

2.10e-0581376HP:0020221
HumanPhenoReduced impulse control

FOCAD CACNA1A BMPR1A NALCN UBE4B GLDC SCN1A SCN2A SCN3A SCN4A SCN8A SCN9A TSC2 ACTL6B DNM1 ADCY3 NLRP3 HTT CDON

2.39e-0510323719HP:5200045
HumanPhenoFocal hemiclonic seizure

SCN1A SCN2A SCN8A SCN9A

2.67e-0525374HP:0006813
HumanPhenoEEG with multifocal slow activity

CACNA1A SCN3A SCN8A ACTL6B DNM1

3.10e-0552375HP:0010844
HumanPhenoMalignant hyperthermia

NALCN SCN4A SCN5A RYR1

3.14e-0526374HP:0002047
HumanPhenoEEG with abnormally slow frequencies

CACNA1A SCN1A SCN3A SCN8A ACTL6B DNM1

3.39e-0588376HP:0011203
HumanPhenoStatus epilepticus without prominent motor symptoms

SCN1A SCN2A SCN9A DNM1

3.67e-0527374HP:0031475
HumanPhenoSimple febrile seizure

SCN1A SCN2A SCN3A SCN8A

3.67e-0527374HP:0011171
HumanPhenoPrenatal movement abnormality

CACNA1A NALCN SCN3A SCN4A SCN8A ACTL6B DNM1 RYR1 ADGRG6

4.67e-05246379HP:0001557
HumanPhenoStatus epilepticus with prominent motor symptoms

CACNA1A SCN1A SCN2A SCN9A

4.92e-0529374HP:0032658
HumanPhenoDialeptic seizure

CACNA1A SCN1A SCN2A SCN3A SCN8A SCN9A TSC2 DNM1 HTT

5.47e-05251379HP:0011146
HumanPhenoLimited neck range of motion

SCN1A SCN2A SCN9A

5.59e-0511373HP:0000466
HumanPhenoProgressive gait ataxia

CACNA1A SCN1A SCN2A SCN9A

5.64e-0530374HP:0007240
HumanPhenoProgressive ataxia

CACNA1A SCN1A SCN2A SCN9A

5.64e-0530374HP:0001329
HumanPhenoParesthesia

CACNA1A BMPR1A SCN1A SCN4A SCN9A SCN10A NLRP3

6.30e-05144377HP:0003401
HumanPhenoDisinhibition

FOCAD CACNA1A BMPR1A NALCN UBE4B GLDC SCN1A SCN2A SCN3A SCN8A SCN9A TSC2 ACTL6B DNM1 HTT CDON

6.51e-058073716HP:0000734
HumanPhenoInappropriate behavior

FOCAD CACNA1A BMPR1A NALCN UBE4B GLDC SCN1A SCN2A SCN3A SCN8A SCN9A TSC2 ACTL6B DNM1 HTT CDON

6.51e-058073716HP:0000719
HumanPhenoAbnormal response to social norms

FOCAD CACNA1A BMPR1A NALCN UBE4B GLDC SCN1A SCN2A SCN3A SCN8A SCN9A TSC2 ACTL6B DNM1 HTT CDON

6.51e-058073716HP:5200123
HumanPhenoSocial disinhibition

FOCAD CACNA1A BMPR1A NALCN UBE4B GLDC SCN1A SCN2A SCN3A SCN8A SCN9A TSC2 ACTL6B DNM1 HTT CDON

6.51e-058073716HP:5200029
HumanPhenoDyskinesia

CACNA1A BMPR1A NALCN SCN2A SCN3A SCN8A ACTL6B DNM1

6.61e-05198378HP:0100660
HumanPhenoAbnormal social development

FOCAD CACNA1A BMPR1A NALCN UBE4B GLDC SCN1A SCN2A SCN3A SCN8A SCN9A TSC2 ACTL6B DNM1 WLS HTT CDON

7.07e-059083717HP:0025732
HumanPhenoEpilepsia partialis continua

SCN1A SCN2A SCN9A

7.42e-0512373HP:0012847
HumanPhenoEncephalopathy

FOCAD CACNA1A GLDC SCN1A SCN2A SCN3A SCN8A ACTL6B DNM1 RYR1

9.30e-053353710HP:0001298
HumanPhenoGeneralized clonic seizure

SCN1A SCN2A SCN8A SCN9A

9.35e-0534374HP:0011169
HumanPhenoCalcaneovalgus deformity

NALCN SCN1A SCN2A SCN9A

9.35e-0534374HP:0001848
HumanPhenoEEG with focal sharp slow waves

CACNA1A SCN1A DNM1

9.60e-0513373HP:0011195
HumanPhenoGeneralized cerebral atrophy/hypoplasia

SCN1A SCN2A SCN9A

9.60e-0513373HP:0007058
HumanPhenoAbnormal blood monovalent inorganic cation concentration

FOCAD BMPR1A PIEZO1 SCN4A SCN5A SCN10A RYR1

9.66e-05154377HP:0010930
HumanPhenoMultifocal epileptiform discharges

SCN1A SCN2A SCN8A SCN9A ACTL6B

9.91e-0566375HP:0010841
HumanPhenoAbnormal stomach morphology

FOCAD CACNA1A BMPR1A NALCN KLF6 UBE4B PIEZO1 SCN3A SCN8A SCN9A ACTL6B DNM1 RYR1 CDON ADGRG6

1.00e-047423715HP:0002577
HumanPhenoDeformed tarsal bones

NALCN SCN1A SCN2A SCN9A

1.05e-0435374HP:0008119
HumanPhenoLimitation of neck motion

CACNA1A SCN1A SCN2A SCN9A

1.18e-0436374HP:0005986
HumanPhenoAbnormal neck physiology

CACNA1A SCN1A SCN2A SCN9A

1.18e-0436374HP:0025669
HumanPhenoDisturbance of facial expression

CACNA1A SCN1A SCN2A SCN9A

1.18e-0436374HP:0005324
HumanPhenoPoor fine motor coordination

FOCAD SCN1A SCN2A SCN9A HTT

1.23e-0469375HP:0007010
HumanPhenoAbnormal T-wave

CACNA1A SCN5A SCN10A RYR1

1.31e-0437374HP:0005135
HumanPhenoAbnormal blood potassium concentration

BMPR1A PIEZO1 SCN4A SCN5A SCN10A RYR1

1.38e-04113376HP:0011042
HumanPhenoPhotosensitive tonic-clonic seizure

SCN1A SCN2A SCN9A

1.51e-0415373HP:0007207
HumanPhenoAbnormally increased volition

FOCAD CACNA1A BMPR1A NALCN UBE4B GLDC SCN1A SCN2A SCN3A SCN8A SCN9A TSC2 ACTL6B DNM1 HTT CDON

1.63e-048693716HP:5200263
HumanPhenoRecurrent maladaptive behavior

FOCAD CACNA1A BMPR1A NALCN UBE4B GLDC SCN1A SCN2A SCN3A SCN4A SCN8A SCN9A TSC2 ACTL6B DNM1 TRRAP ADCY3 NLRP3 HTT CDON

1.74e-0412933720HP:5200241
HumanPhenoFocal non-motor seizure

CACNA1A SCN1A SCN2A SCN8A

1.79e-0440374HP:0032679
HumanPhenoShort attention span

FOCAD CACNA1A BMPR1A SCN1A SCN2A SCN3A SCN8A SCN9A TSC2 ACTL6B DNM1 CDON

1.81e-045173712HP:0000736
HumanPhenoEpileptic encephalopathy

CACNA1A SCN1A SCN2A SCN3A SCN8A DNM1

1.84e-04119376HP:0200134
HumanPhenoDysgenesis of the hippocampus

SCN1A SCN2A SCN9A

1.85e-0416373HP:0025101
HumanPhenoReduced attention regulation

FOCAD CACNA1A BMPR1A SCN1A SCN2A SCN3A SCN8A SCN9A TSC2 ACTL6B DNM1 CDON

2.13e-045263712HP:5200044
HumanPhenoDecreased fetal movement

CACNA1A SCN3A SCN4A SCN8A ACTL6B DNM1 RYR1 ADGRG6

2.13e-04234378HP:0001558
HumanPhenoFocal clonic seizure

SCN1A SCN2A SCN8A SCN9A

2.17e-0442374HP:0002266
HumanPhenoMyoclonus

CACNA1A GLDC SCN1A SCN2A SCN3A SCN8A SCN9A ACTL6B DNM1 HTT

2.18e-043713710HP:0001336
HumanPhenoFocal motor status epilepticus

SCN1A SCN2A SCN9A

2.24e-0417373HP:0032663
HumanPhenoAbnormal fetal physiology

CACNA1A NALCN SCN3A SCN4A SCN8A ACTL6B DNM1 RYR1 ADGRG6

2.65e-04308379HP:0034059
HumanPhenoVisually-induced seizure

SCN1A SCN2A SCN9A

2.67e-0418373HP:0020216
HumanPhenoPersonality disorder

CACNA1A SCN1A DNM1

2.67e-0418373HP:0012075
HumanPhenoAbnormal eating behavior

CACNA1A UBE4B SCN4A DNM1 ADCY3 HTT

2.75e-04128376HP:0100738
HumanPhenoHypsarrhythmia

CACNA1A SCN1A SCN2A SCN3A SCN8A ACTL6B DNM1

3.04e-04185377HP:0002521
HumanPhenoAlien limb phenomenon

CACNA1A SCN1A

3.05e-044372HP:0032506
HumanPhenoFocal manual automatism seizure

CACNA1A SCN1A

3.05e-044372HP:0032900
HumanPhenoFocal pedal automatism seizure

CACNA1A SCN1A

3.05e-044372HP:0032901
HumanPhenoDissociated sensory loss

CACNA1A SCN1A

3.05e-044372HP:0010835
HumanPhenoBlurred vision

CACNA1A SCN4A SCN9A NLRP3

3.09e-0446374HP:0000622
HumanPhenoPoor motor coordination

FOCAD SCN1A SCN2A SCN9A HTT

3.29e-0485375HP:0002275
HumanPhenoHyperactivity

CACNA1A BMPR1A GLDC SCN1A SCN2A SCN3A SCN8A TSC2 ACTL6B DNM1 HTT CDON

3.72e-045583712HP:0000752
HumanPhenoAbnormal exteroceptive sensation

CACNA1A BMPR1A NALCN SCN1A SCN4A SCN9A SCN10A NLRP3

4.27e-04259378HP:0033747
HumanPhenoTalipes valgus

SCN1A SCN2A SCN9A

4.29e-0421373HP:0004684
HumanPhenoDysesthesia

SCN9A SCN10A NLRP3

4.29e-0421373HP:0012534
HumanPhenoTonic seizure

CACNA1A SCN1A SCN2A SCN8A SCN9A DNM1

4.46e-04140376HP:0032792
HumanPhenoApathy

CACNA1A SCN1A DNM1 HTT CDON

4.52e-0491375HP:0000741
HumanPhenoSecond trimester onset

SCN4A SCN5A TSC2 ADGRG6

4.61e-0451374HP:0034198
HumanPhenoAutism

CACNA1A UBE4B SCN2A SCN3A SCN8A TSC2 ACTL6B DNM1

4.86e-04264378HP:0000717
HumanPhenoReflex seizure

SCN1A SCN2A SCN9A

4.94e-0422373HP:0020207
HumanPhenoFocal sensory seizure

CACNA1A SCN1A SCN8A

4.94e-0422373HP:0011157
HumanPhenoNeonatal electro-clinical non-motor seizure

SCN2A SCN8A

5.06e-045372HP:0032812
HumanPhenoNeonatal seizure with electrographic correlate

SCN2A SCN8A

5.06e-045372HP:0032808
HumanPhenoNeonatal electro-clinical seizure

SCN2A SCN8A

5.06e-045372HP:0032809
HumanPhenoNeonatal electro-clinical seizure with behavior arrest

SCN2A SCN8A

5.06e-045372HP:0032823
HumanPhenoSeesaw nystagmus

CACNA1A SCN1A

5.06e-045372HP:0012044
HumanPhenoFocal head nodding automatism seizure

SCN2A SCN8A

5.06e-045372HP:0032906
HumanPhenoSpontaneous pain sensation

CACNA1A SCN1A

5.06e-045372HP:0010833
HumanPhenoAllodynia

SCN9A SCN10A

5.06e-045372HP:0012533
HumanPhenoAtonic seizure

CACNA1A SCN1A SCN2A SCN9A DNM1

5.25e-0494375HP:0010819
HumanPhenoInfection-related seizure

CACNA1A SCN1A SCN2A SCN3A SCN8A SCN9A

5.38e-04145376HP:0032892
HumanPhenoSeizure precipitated by febrile infection

CACNA1A SCN1A SCN2A SCN3A SCN8A SCN9A

5.38e-04145376HP:0032894
MousePhenoabnormal brain wave pattern

CACNA1A NALCN SCN1A SCN10A LRRC4B DNM1

7.56e-0764706MP:0004994
MousePhenoabnormal neurite morphology

CACNA1A GPR158 SCN1A CAMSAP3 TSC2 ACTL6B DNM1 ECPAS ADCY3 CALN1 HTT ADGRG6

1.73e-064427012MP:0008415
MousePhenoabnormal synaptic transmission

CACNA1A LAPTM4A USP38 NALCN GPR158 SCN1A SCN2A DHFR2 SCN8A SCN9A LRRC4B TSC2 DNM1 ECPAS FITM2 ADCY3 SLC29A1 CALN1

3.57e-0610707018MP:0003635
MousePhenoabnormal synaptic physiology

CACNA1A LAPTM4A USP38 NALCN GPR158 SCN1A SCN2A DHFR2 SCN8A SCN9A LRRC4B TSC2 DNM1 ECPAS FITM2 ADCY3 SLC29A1 CALN1

3.87e-0610767018MP:0021009
MousePhenoabnormal action potential

CACNA1A SCN1A SCN2A SCN5A SCN8A SCN9A SCN10A

4.39e-06133707MP:0005402
MousePhenoabnormal nervous system electrophysiology

CACNA1A NALCN SCN1A SCN2A SCN5A SCN8A SCN9A SCN10A LRRC4B DNM1

5.16e-063297010MP:0002272
MousePhenoabnormal seizure response to inducing agent

CACNA1A SLC6A11 SCN1A SCN8A SCN9A LRRC4B DNM1 ECPAS

6.99e-06201708MP:0009357
MousePhenoimpaired limb coordination

CACNA1A SCN8A DNM1 HTT ADGRG6

1.11e-0559705MP:0001524
MousePhenoseizures

CACNA1A SLC6A11 SCN1A SCN5A SCN8A SCN9A LRRC4B DNM1 ECPAS HTT

1.14e-053607010MP:0002064
MousePhenoabnormal CNS synaptic transmission

CACNA1A LAPTM4A USP38 GPR158 SCN1A SCN2A DHFR2 SCN9A LRRC4B TSC2 DNM1 ECPAS FITM2 ADCY3 SLC29A1 CALN1

2.17e-059857016MP:0002206
MousePhenoabnormal dendrite morphology

CACNA1A GPR158 SCN1A TSC2 ACTL6B DNM1 ADCY3 CALN1

2.32e-05237708MP:0008143
MousePhenoincreased susceptibility to malignant hyperthermia

RYR1 HTT

2.47e-052702MP:0020214
MousePhenoabnormal posture

CACNA1A SCN1A CAMSAP3 SCN8A SCN10A DNM1 RYR1 HTT

2.77e-05243708MP:0001504
MousePhenolethality during fetal growth through weaning, incomplete penetrance

CACNA1A GLDC SCN1A SCN4A SCN5A CAMSAP3 SCN8A SCN9A KDM2B LRRC4B TSC2 ACTL6B DNAH5 BAG6 ADCY3 HTT CDON

2.86e-0511247017MP:0011112
MousePhenolethality during fetal growth through weaning, complete penetrance

CACNA1A NALCN UBE4B SCN1A PIEZO1 SCN2A SCN4A DHFR2 SCN8A SCN9A TSC2 DNM1 WLS BAG6 ADCY3 NLRP3 RYR1 HTT

3.72e-0512697018MP:0011111
MousePhenodomed cranium

GLDC DNAH5 RYR1 HTT CDON

6.55e-0585705MP:0000440
MousePhenoabnormal seizure response to pharmacological agent

CACNA1A SLC6A11 SCN1A SCN8A LRRC4B ECPAS

9.20e-05147706MP:0000950
MousePhenoabnormal excitatory postsynaptic current frequency

GPR158 SCN2A LRRC4B

1.10e-0419703MP:0014377
MousePhenoenlarged brain ventricles

GLDC SCN8A LRRC4B DNAH5 HTT CDON

1.28e-04156706MP:0011380
MousePhenoabnormal breathing pattern

NALCN SCN1A SCN2A SCN4A SCN8A SCN10A DNAH5 RYR1

1.31e-04303708MP:0001951
MousePhenoabnormal behavioral response to xenobiotic

CACNA1A SLC6A11 SCN1A SCN8A LRRC4B ECPAS SLC29A1 RYR1

1.49e-04309708MP:0009745
MousePhenoakinesia

SCN1A SCN4A ADGRG6

1.50e-0421703MP:0002690
MousePhenoabnormal brain ventricle size

GLDC SCN8A LRRC4B DNAH5 HTT CDON

1.68e-04164706MP:0013229
MousePhenoabnormal spike wave discharge

CACNA1A SCN1A SCN8A

2.26e-0424703MP:0008840
MousePhenoabnormal locomotor activation

SCN1A SCN4A MC3R HTT ADGRG6

2.41e-04112705MP:0003313
MousePhenoincreased taurine level

CACNA1A HTT

2.45e-045702MP:0030635
MousePhenopostnatal lethality

CACNA1A GLDC SCN1A SCN2A SCN5A CAMSAP3 SCN8A SCN9A LRRC4B ACTL6B DNM1 DNAH5 ADCY3 NLRP3 CDON

2.50e-0410847015MP:0002082
MousePhenobrain atrophy

CACNA1A DNAH5 HTT

2.56e-0425703MP:0012506
MousePhenomuscle twitch

CACNA1A SCN4A SCN8A RYR1

2.92e-0464704MP:0009046
MousePhenoabnormal excitatory postsynaptic currents

CACNA1A GPR158 SCN2A LRRC4B SLC29A1

3.20e-04119705MP:0002910
MousePhenoabnormal endocardium morphology

SCN8A TSC2 ADGRG6

3.23e-0427703MP:0003974
MousePhenoapnea

NALCN SCN1A SCN10A

3.23e-0427703MP:0001957
MousePhenoimpaired muscle relaxation

SCN4A SCN8A RYR1

3.60e-0428703MP:0003157
MousePhenoabnormal nervous system development

CACNA1A BMPR1A NALCN GLDC SCN8A FRS2 KDM2B TSC2 ACTL6B DNM1 WLS DNAH5 BAG6 HTT CDON ADGRG6

3.87e-0412577016MP:0003861
MousePhenoventricular fibrillation

SCN1A SCN5A

5.11e-047702MP:0006110
MousePhenoincreased glycine level

CACNA1A GLDC

5.11e-047702MP:0030658
MousePhenoanosmia

SCN9A ADCY3

5.11e-047702MP:0004512
MousePhenoabnormal heart ventricle morphology

CMIP SLC10A2 GLDC SCN5A CAMSAP3 SCN8A CTNNA3 TSC2 FITM2 DNAH5 RYR1 ADGRG6

5.19e-047937012MP:0005294
MousePhenoabnormal seizure response to electrical stimulation

SCN1A SCN9A DNM1

5.37e-0432703MP:0001650
MousePhenoabnormal muscle electrophysiology

CACNA1A SCN4A RYR1

5.37e-0432703MP:0004145
MousePhenoabnormal brain size

SCN1A CAMSAP3 FRS2 KDM2B LRRC4B WLS ADCY3 HTT

5.50e-04375708MP:0000771
MousePhenoabnormal brain ventricle morphology

GLDC SCN8A KDM2B LRRC4B DNAH5 HTT CDON

5.56e-04286707MP:0000822
MousePhenoabnormal channel response

CACNA1A NALCN SCN2A

5.89e-0433703MP:0003484
MousePhenoimpaired coordination

CACNA1A UBE4B SCN4A SCN8A LRRC4B CERS6 DNM1 HTT ADGRG6

6.04e-04478709MP:0001405
MousePhenoincreased amino acid level

CACNA1A GLDC CAMSAP3 HTT

6.53e-0479704MP:0014527
MousePhenodecreased brain size

SCN1A CAMSAP3 FRS2 LRRC4B WLS ADCY3 HTT

6.68e-04295707MP:0000774
MousePhenoabnormal hindbrain morphology

CACNA1A UBE4B SCN8A FRS2 KDM2B OCLN DNM1 DNAH5 HTT

6.70e-04485709MP:0000841
MousePhenoabnormal cerebellum morphology

CACNA1A UBE4B SCN8A FRS2 OCLN DNM1 DNAH5 HTT

7.00e-04389708MP:0000849
MousePhenoabsence seizures

CACNA1A SCN1A SCN8A

7.02e-0435703MP:0003216
MousePhenoabnormal forebrain morphology

CMIP SCN1A CAMSAP3 FRS2 LRRC4B CERS6 OCLN WLS DNAH5 BAG6 ADCY3 CALN1 HTT CDON

7.44e-0410727014MP:0000783
MousePhenoabnormal respiration

CACNA1A NALCN SCN1A SCN2A SCN4A SCN8A SCN10A DNAH5 BAG6 RYR1

7.45e-045987010MP:0001943
MousePhenoenlarged lateral ventricles

LRRC4B DNAH5 HTT CDON

8.23e-0484704MP:0008535
MousePhenoabnormal respiratory function

NALCN SCN1A SCN2A SCN4A SCN8A SCN10A DNAH5 RYR1

8.26e-04399708MP:0002327
MousePhenoabnormal brainstem morphology

CACNA1A UBE4B SCN2A KDM2B BAG6 HTT

9.46e-04227706MP:0005277
MousePhenoconvulsive seizures

CACNA1A SCN1A SCN8A DNM1 HTT

1.00e-03153705MP:0000947
MousePhenononconvulsive seizures

CACNA1A SCN1A SCN8A

1.04e-0340703MP:0000948
MousePhenodecreased excitatory postsynaptic current frequency

SCN2A LRRC4B

1.08e-0310702MP:0014379
MousePhenoabnormal embryonic tissue morphology

BMPR1A CMIP NALCN GLDC PIEZO1 SCN5A FRS2 KDM2B TSC2 DNM1 WLS TRRAP HTT CDON

1.10e-0311167014MP:0002085
MousePhenoabnormal metencephalon morphology

CACNA1A UBE4B SCN8A FRS2 OCLN DNM1 DNAH5 HTT

1.15e-03420708MP:0000847
MousePhenoabnormal adaptive thermogenesis

GPR158 ULK2 RYR1 HTT

1.35e-0396704MP:0011019
MousePhenoabnormal cerebellum development

CACNA1A SCN8A FRS2 HTT

1.35e-0396704MP:0000854
MousePhenolethality throughout fetal growth and development

UBE4B SCN1A PIEZO1 KDM2B TSC2 BAG6 RYR1 HTT

1.44e-03435708MP:0006208
MousePhenomuscle weakness

CACNA1A SCN4A SCN8A RYR1

1.46e-0398704MP:0000747
MousePhenoabnormal respiratory system physiology

CACNA1A USP38 NALCN SCN1A SCN2A SCN4A SCN8A SCN10A DNAH5 BAG6 ZAP70 RYR1

1.52e-038977012MP:0002133
MousePhenoabnormal response to stress-induced hyperthermia

GPR158 ULK2

1.58e-0312702MP:0010165
MousePhenoincreased embryonic epiblast cell apoptosis

BMPR1A HTT

1.58e-0312702MP:0011191
MousePhenoabnormal folic acid level

GLDC DHFR2

1.58e-0312702MP:0011230
MousePhenoostium secundum atrial septal defect

DNAH5 RYR1

1.58e-0312702MP:0010405
DomainNa_channel_asu

SCN1A SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A SCN9A SCN10A

2.70e-2110799IPR001696
DomainNa_trans_assoc

SCN1A SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A SCN9A SCN10A

2.70e-2110799IPR010526
DomainNa_trans_assoc

SCN1A SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A SCN9A SCN10A

2.70e-2110799PF06512
DomainChannel_four-helix_dom

CACNA1A NALCN SCN1A SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A SCN9A SCN10A

5.93e-16577911IPR027359
Domain-

CACNA1A NALCN SCN1A SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A SCN9A SCN10A

5.93e-165779111.20.120.350
DomainNa_trans_cytopl

SCN1A SCN2A SCN3A SCN5A SCN8A SCN9A

4.72e-156796PF11933
DomainNa_trans_cytopl

SCN1A SCN2A SCN3A SCN5A SCN8A SCN9A

4.72e-156796IPR024583
DomainIon_trans_dom

CACNA1A NALCN SCN1A SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A SCN9A SCN10A RYR1

5.38e-141147912IPR005821
DomainIon_trans

CACNA1A NALCN SCN1A SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A SCN9A SCN10A RYR1

5.38e-141147912PF00520
DomainIQ_motif_EF-hand-BS

SCN1A SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A SCN9A SCN10A

1.45e-1090799IPR000048
DomainIQ

SCN1A SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A SCN9A

1.79e-0981798SM00015
DomainIQ

SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A

5.43e-0993798PS50096
DomainIQ

SCN1A SCN3A SCN4A SCN8A SCN9A SCN10A

5.43e-0771796PF00612
DomainARM-type_fold

FOCAD FMNL3 TSC2 ECPAS TRRAP WDFY4 HTT TANGO6

9.23e-05339798IPR016024
DomainEF-hand-dom_pair

SCN1A SCN3A SCN7A SCN8A SCN9A CALN1 RYR1

2.12e-04287797IPR011992
DomainDynamin_central

DNM3 DNM1

2.62e-046792IPR000375
DomainGED

DNM3 DNM1

2.62e-046792SM00302
DomainGED

DNM3 DNM1

2.62e-046792PS51388
DomainDynamin_M

DNM3 DNM1

2.62e-046792PF01031
DomainDynamin_GTPase_CS

DNM3 DNM1

2.62e-046792IPR019762
DomainGED_dom

DNM3 DNM1

2.62e-046792IPR020850
DomainGED

DNM3 DNM1

2.62e-046792PF02212
DomainGED

DNM3 DNM1

2.62e-046792IPR003130
Domain-

TSC2 ECPAS TRRAP WDFY4 HTT TANGO6

3.56e-042227961.25.10.10
DomainG_DYNAMIN_1

DNM3 DNM1

3.66e-047792PS00410
DomainDYNc

DNM3 DNM1

3.66e-047792SM00053
DomainGPS

PKDREJ ADGRG4 ADGRG6

3.97e-0434793SM00303
DomainGPS

PKDREJ ADGRG4 ADGRG6

5.10e-0437793IPR000203
DomainPTX

ADGRG4 ADGRG6

7.78e-0410792SM00159
DomainPentaxin-related

ADGRG4 ADGRG6

9.48e-0411792IPR001759
DomainPentaxin

ADGRG4 ADGRG6

9.48e-0411792PF00354
DomainARM-like

TSC2 ECPAS TRRAP WDFY4 HTT TANGO6

9.93e-04270796IPR011989
DomainG_DYNAMIN_dom

DNM3 DNM1

1.56e-0314792IPR030381
DomainG_DYNAMIN_2

DNM3 DNM1

1.56e-0314792PS51718
DomainDynamin_GTPase

DNM3 DNM1

1.79e-0315792IPR001401
DomainDynamin_N

DNM3 DNM1

1.79e-0315792PF00350
DomainDynamin_SF

DNM3 DNM1

1.79e-0315792IPR022812
DomainHEAT_REPEAT

ECPAS HTT TANGO6

3.25e-0370793PS50077
PathwayREACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS

SCN1A SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A SCN9A SCN10A

9.86e-1531659M877
PathwayREACTOME_PHASE_0_RAPID_DEPOLARISATION

SCN1A SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A SCN9A SCN10A

1.37e-1432659M27455
PathwayREACTOME_L1CAM_INTERACTIONS

SCN1A SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A SCN9A SCN10A DNM3 DNM1

7.11e-121216511M872
PathwayREACTOME_CARDIAC_CONDUCTION

SCN1A SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A SCN9A SCN10A RYR1

3.65e-101306510M27454
PathwayREACTOME_MUSCLE_CONTRACTION

SCN1A SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A SCN9A SCN10A RYR1

2.76e-082036510M5485
PathwayWP_RETT_SYNDROME

SCN1A SCN2A SCN8A ACTL6B TRRAP HTT

8.00e-0848656M39759
PathwayREACTOME_NERVOUS_SYSTEM_DEVELOPMENT

SCN1A SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A SCN9A SCN10A FRS2 DNM3 DNM1 ADGRG6

1.76e-065756513M29853
PathwayWP_ADHD_AND_AUTISM_ASD_PATHWAYS

SCN1A SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A SCN9A SCN10A TSC2

6.33e-063676510M48346
PathwayWP_DRAVET_SYNDROME

SCN1A SCN2A SCN3A SCN8A

7.76e-0628654M45519
PathwayWP_10Q1121Q1123_COPY_NUMBER_VARIATION_SYNDROME

BMPR1A MAPK8 WDFY4 NLRP3

1.76e-0461654M48077
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_TNF_JNK_SIGNALING_PATHWAY

MAPK8 HTT

3.10e-046652M47680
Pubmed

International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels.

SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A

5.45e-21981816382098
Pubmed

A 'toothache tree' alkylamide inhibits Aδ mechanonociceptors to alleviate mechanical pain.

SCN1A SCN2A SCN3A SCN8A SCN9A SCN10A

1.32e-16681623652591
Pubmed

Regulation of neuronal voltage-gated sodium channels by the ubiquitin-protein ligases Nedd4 and Nedd4-2.

SCN1A SCN2A SCN3A SCN5A SCN8A SCN9A SCN10A

4.83e-161381715123669
Pubmed

Expression pattern of neuronal and skeletal muscle voltage-gated Na+ channels in the developing mouse heart.

SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A

1.10e-14981615746173
Pubmed

Structure/function characterization of micro-conotoxin KIIIA, an analgesic, nearly irreversible blocker of mammalian neuronal sodium channels.

SCN2A SCN3A SCN4A SCN5A SCN8A

6.04e-14581517724025
Pubmed

Nav1.1 localizes to axons of parvalbumin-positive inhibitory interneurons: a circuit basis for epileptic seizures in mice carrying an Scn1a gene mutation.

SCN1A SCN2A SCN3A SCN8A

2.73e-11481417537961
Pubmed

Sodium channel expression and transcript variation in the developing brain of human, Rhesus monkey, and mouse.

SCN1A SCN2A SCN3A SCN8A

2.73e-11481435031483
Pubmed

Abnormal changes in voltage-gated sodium channels subtypes NaV1.1, NaV1.2, NaV1.3, NaV1.6 and CaM/CaMKII pathway in low-grade astrocytoma.

SCN1A SCN2A SCN3A SCN8A

2.73e-11481429578003
Pubmed

Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development.

CACNA1A SCN1A SCN3A SCN4A SCN5A SCN7A SCN8A SCN9A SCN10A

4.09e-1113981916985003
Pubmed

Nav1.2 haplodeficiency in excitatory neurons causes absence-like seizures in mice.

SCN1A SCN2A SCN3A SCN5A SCN8A

4.73e-111281530175250
Pubmed

A new sodium channel alpha-subunit gene (Scn9a) from Schwann cells maps to the Scn1a, Scn2a, Scn3a cluster of mouse chromosome 2.

SCN1A SCN2A SCN3A SCN9A

1.36e-1058148812438
Pubmed

Early development of electrical excitability in the mouse enteric nervous system.

SCN3A SCN5A SCN8A SCN9A

1.36e-10581422875929
Pubmed

Voltage-gated sodium channels in taste bud cells.

SCN2A SCN3A SCN9A

1.22e-08381319284629
Pubmed

Mutations in the sodium channel genes SCN1A, SCN3A, and SCN9A in children with epilepsy with febrile seizures plus(EFS+).

SCN1A SCN3A SCN9A

1.22e-08381333895391
Pubmed

SCN1A, SCN2A and SCN3A gene polymorphisms and responsiveness to antiepileptic drugs: a multicenter cohort study and meta-analysis.

SCN1A SCN2A SCN3A

1.22e-08381323859570
Pubmed

Sodium channels SCN1A, SCN2A and SCN3A in familial autism.

SCN1A SCN2A SCN3A

1.22e-08381312610651
Pubmed

Abnormal expression of voltage-gated sodium channels Nav1.7, Nav1.3 and Nav1.8 in trigeminal neuralgia.

SCN3A SCN9A SCN10A

1.22e-08381319699781
Pubmed

Multidrug resistance in epilepsy and polymorphisms in the voltage-gated sodium channel genes SCN1A, SCN2A, and SCN3A: correlation among phenotype, genotype, and mRNA expression.

SCN1A SCN2A SCN3A

1.22e-08381318784617
Pubmed

Characterization of 5' untranslated regions of the voltage-gated sodium channels SCN1A, SCN2A, and SCN3A and identification of cis-conserved noncoding sequences.

SCN1A SCN2A SCN3A

1.22e-08381317544618
Pubmed

Variable patterns of mutation density among NaV1.1, NaV1.2 and NaV1.6 point to channel-specific functional differences associated with childhood epilepsy.

SCN1A SCN2A SCN8A

1.22e-08381332845893
Pubmed

Human voltage-gated sodium channel mutations that cause inherited neuronal and muscle channelopathies increase resurgent sodium currents.

SCN4A SCN5A SCN9A

1.22e-08381320038812
Pubmed

Comparison and optimization of in silico algorithms for predicting the pathogenicity of sodium channel variants in epilepsy.

SCN1A SCN2A SCN8A

1.22e-08381328518218
Pubmed

Reduced sodium current in Purkinje neurons from Nav1.1 mutant mice: implications for ataxia in severe myoclonic epilepsy in infancy.

SCN1A SCN2A SCN8A

1.22e-08381317928448
Pubmed

Early expression of sodium channel transcripts and sodium current by cajal-retzius cells in the preplate of the embryonic mouse neocortex.

SCN1A SCN2A SCN3A

1.22e-08381314973256
Pubmed

Confirmation of quantitative trait loci for alcohol preference in mice.

SCN1A SCN2A SCN3A SCN7A

3.65e-08158149726281
Pubmed

Evolution and diversity of mammalian sodium channel genes.

SCN7A SCN9A SCN10A

4.86e-08481310198179
Pubmed

Dorsal root ganglia isolated from Nf1+/- mice exhibit increased levels of mRNA expression of voltage-dependent sodium channels.

SCN1A SCN9A SCN10A

4.86e-08481322260870
Pubmed

Association of sodium voltage-gated channel genes polymorphisms with epilepsy risk and prognosis in the Saudi population.

SCN1A SCN2A SCN3A

4.86e-08481335801810
Pubmed

Neuronal voltage-gated ion channels are genetic modifiers of generalized epilepsy with febrile seizures plus.

SCN1A SCN2A SCN8A

4.86e-08481321156207
Pubmed

Use of recombinant inbred strains for studying genetic determinants of responses to alcohol.

SCN1A SCN2A SCN3A

4.86e-0848138974318
Pubmed

Three brain sodium channel alpha-subunit genes are clustered on the proximal segment of mouse chromosome 2.

SCN1A SCN2A SCN3A

1.21e-0758131679748
Pubmed

Case-control association study of polymorphisms in the voltage-gated sodium channel genes SCN1A, SCN2A, SCN3A, SCN1B, and SCN2B and epilepsy.

SCN1A SCN2A SCN3A

1.21e-07581324337656
Pubmed

Contactin regulates the current density and axonal expression of tetrodotoxin-resistant but not tetrodotoxin-sensitive sodium channels in DRG neurons.

SCN8A SCN9A SCN10A

2.42e-07681316029194
Pubmed

An animal model of oxaliplatin-induced cold allodynia reveals a crucial role for Nav1.6 in peripheral pain pathways.

SCN3A SCN8A SCN10A

2.42e-07681323711479
Pubmed

Diagnostic yield of genetic testing in epileptic encephalopathy in childhood.

SCN1A SCN2A SCN8A

4.23e-07781325818041
Pubmed

Tyrosine-phosphorylated and nonphosphorylated sodium channel beta1 subunits are differentially localized in cardiac myocytes.

SCN1A SCN5A SCN8A

4.23e-07781315272007
Pubmed

Pain without nociceptors? Nav1.7-independent pain mechanisms.

SCN3A SCN9A SCN10A

4.23e-07781324440715
Pubmed

Significant determinants of mouse pain behaviour.

SCN3A SCN9A SCN10A

6.76e-07881325101983
Pubmed

Interaction of muscle and brain sodium channels with multiple members of the syntrophin family of dystrophin-associated proteins.

SCN1A SCN4A SCN5A

6.76e-0788139412493
Pubmed

Sodium channel Scn1b null mice exhibit prolonged QT and RR intervals.

SCN1A SCN5A SCN8A

1.01e-06981317884088
Pubmed

Genetic mapping of the peripheral sodium channel genes, Scn9a and Scn10a, in the mouse.

SCN3A SCN9A SCN10A

1.01e-0698138854872
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

FOCAD UBQLNL SCN3A CAMSAP3 SCN8A FRS2 RNF213 TSC2 ECPAS DNAJA1 RYR1

1.12e-06736811129676528
Pubmed

Quantitative trait loci mapping of genes that influence the sensitivity and tolerance to ethanol-induced hypothermia in BXD recombinant inbred mice.

SCN1A SCN2A SCN3A

2.64e-06128138169823
Pubmed

CTDP1 regulates breast cancer survival and DNA repair through BRCT-specific interactions with FANCI.

UBE4B RNF213 TSC2 TRRAP HTT

4.64e-0610481531240132
Pubmed

A common genetic variant within SCN10A modulates cardiac SCN5A expression.

SCN5A SCN10A

5.36e-06281224642470
Pubmed

Array-CGH detection of a de novo 2.8 Mb deletion in 2q24.2-->q24.3 in a girl with autistic features and developmental delay.

SCN2A SCN3A

5.36e-06281220346423
Pubmed

Reduction of Kcnt1 is therapeutic in mouse models of SCN1A and SCN8A epilepsy.

SCN1A SCN8A

5.36e-06281237901435
Pubmed

Large-scale phosphoproteome analysis of human liver tissue by enrichment and fractionation of phosphopeptides with strong anion exchange chromatography.

RNF213 OCLN

5.36e-06281218318008
Pubmed

State- and use-dependent block of muscle Nav1.4 and neuronal Nav1.7 voltage-gated Na+ channel isoforms by ranolazine.

SCN4A SCN9A

5.36e-06281218079277
Pubmed

An Scn1a epilepsy mutation in Scn8a alters seizure susceptibility and behavior.

SCN1A SCN8A

5.36e-06281226410685
Pubmed

Neuronal death and perinatal lethality in voltage-gated sodium channel alpha(II)-deficient mice.

SCN1A SCN2A

5.36e-06281210827969
Pubmed

Differential role of sodium channels SCN1A and SCN2A gene polymorphisms with epilepsy and multiple drug resistance in the north Indian population.

SCN1A SCN2A

5.36e-06281219694741
Pubmed

Commonalities and distinctions between two neurodevelopmental disorder subtypes associated with SCN2A and SCN8A variants and literature review.

SCN2A SCN8A

5.36e-06281235348308
Pubmed

Genomic structures of SCN2A and SCN3A - candidate genes for deafness at the DFNA16 locus.

SCN2A SCN3A

5.36e-06281211245985
Pubmed

Whole-genome sequencing identifies ADGRG6 enhancer mutations and FRS2 duplications as angiogenesis-related drivers in bladder cancer.

FRS2 ADGRG6

5.36e-06281230755618
Pubmed

Novel isoforms of the sodium channels Nav1.8 and Nav1.5 are produced by a conserved mechanism in mouse and rat.

SCN5A SCN10A

5.36e-06281215047701
Pubmed

Electrophysiological properties of two axonal sodium channels, Nav1.2 and Nav1.6, expressed in mouse spinal sensory neurones.

SCN2A SCN8A

5.36e-06281215760941
Pubmed

Differential expression of two sodium channel subtypes in human brain.

SCN1A SCN2A

5.36e-0628121317301
Pubmed

Duplication of the sodium channel gene cluster on 2q24 in children with early onset epilepsy.

SCN2A SCN3A

5.36e-06281223016767
Pubmed

Whole gene duplication of SCN2A and SCN3A is associated with neonatal seizures and a normal intellectual development.

SCN2A SCN3A

5.36e-06281227153334
Pubmed

Electrophysiological Differences between the Same Pore Region Mutation in SCN1A and SCN3A.

SCN1A SCN3A

5.36e-06281224990319
Pubmed

Na+ current properties in islet α- and β-cells reflect cell-specific Scn3a and Scn9a expression.

SCN3A SCN9A

5.36e-06281225172946
Pubmed

Clinical exome sequencing identifies two novel mutations of the SCN1A and SCN2A genes in Moroccan patients with epilepsy: a case series.

SCN1A SCN2A

5.36e-06281231439038
Pubmed

Dynamin is primed at endocytic sites for ultrafast endocytosis.

DNM3 DNM1

5.36e-06281235809574
Pubmed

Scn8a Antisense Oligonucleotide Is Protective in Mouse Models of SCN8A Encephalopathy and Dravet Syndrome.

SCN1A SCN8A

5.36e-06281231943325
Pubmed

Mouse heart Na+ channels: primary structure and function of two isoforms and alternatively spliced variants.

SCN4A SCN5A

5.36e-06281211834499
Pubmed

A dynamin 1-, dynamin 3- and clathrin-independent pathway of synaptic vesicle recycling mediated by bulk endocytosis.

DNM3 DNM1

5.36e-06281224963135
Pubmed

Severe epilepsy, retardation, and dysmorphic features with a 2q deletion including SCN1A and SCN2A.

SCN1A SCN2A

5.36e-06281215249644
Pubmed

Mapping of a FEB3 homologous febrile seizure locus on mouse chromosome 2 containing candidate genes Scn1a and Scn3a.

SCN1A SCN3A

5.36e-06281227690330
Pubmed

Crystal structure of the dynamin tetramer.

DNM3 DNM1

5.36e-06281226302298
Pubmed

Sodium channel slow inactivation interferes with open channel block.

SCN8A SCN9A

5.36e-06281227174182
Pubmed

Reduced expression of Na(v)1.6 sodium channels and compensation by Na(v)1.2 channels in mice heterozygous for a null mutation in Scn8a.

SCN2A SCN8A

5.36e-06281218601978
Pubmed

Mutations in SCN10A are responsible for a large fraction of cases of Brugada syndrome.

SCN5A SCN10A

5.36e-06281224998131
Pubmed

Correlations in timing of sodium channel expression, epilepsy, and sudden death in Dravet syndrome.

SCN1A SCN3A

5.36e-06281223965409
Pubmed

FGF14 N-terminal splice variants differentially modulate Nav1.2 and Nav1.6-encoded sodium channels.

SCN2A SCN8A

5.36e-06281219465131
Pubmed

Isoform-specific effects of the beta2 subunit on voltage-gated sodium channel gating.

SCN2A SCN5A

5.36e-06281216847056
Pubmed

From GWAS to function: genetic variation in sodium channel gene enhancer influences electrical patterning.

SCN5A SCN10A

5.36e-06281224360055
Pubmed

SCN1A and SCN2A polymorphisms are associated with response to valproic acid in Chinese epilepsy patients.

SCN1A SCN2A

5.36e-06281230693367
Pubmed

Block of a subset of sodium channels exacerbates experimental autoimmune encephalomyelitis.

SCN2A SCN8A

5.36e-06281223735284
Pubmed

Single nucleotide polymorphisms of SCN5A and SCN10A genes increase the risk of ventricular arrhythmias during myocardial infarction.

SCN5A SCN10A

5.36e-06281232330377
Pubmed

Association between SCN1A and SCN2A mutations and clinical/EEG features in Chinese patients from epilepsy or severe seizures.

SCN1A SCN2A

5.36e-06281229649454
Pubmed

Classical dynamin DNM1 and DNM3 genes attain maximum expression in the normal human central nervous system.

DNM3 DNM1

5.36e-06281224673776
Pubmed

Kinetic Analysis of Membrane Potential Dye Response to NaV1.7 Channel Activation Identifies Antagonists with Pharmacological Selectivity against NaV1.5.

SCN5A SCN9A

5.36e-06281226861708
Pubmed

Neuropathic pain develops normally in mice lacking both Na(v)1.7 and Na(v)1.8.

SCN9A SCN10A

5.36e-06281216111501
Pubmed

Effects of SCN1A and SCN2A polymorphisms on responsiveness to valproic acid monotherapy in epileptic children.

SCN1A SCN2A

5.36e-06281233096315
Pubmed

Ca2+-dependent regulation of sodium channels NaV1.4 and NaV1.5 is controlled by the post-IQ motif.

SCN4A SCN5A

5.36e-06281230944319
Pubmed

Dynamin GTPase regulation is altered by PH domain mutations found in centronuclear myopathy patients.

DNM3 DNM1

5.36e-06281220700106
Pubmed

Comparable clinical characteristics in Brugada syndrome patients harboring SCN5A or novel SCN10A variants.

SCN5A SCN10A

5.36e-06281231292628
Pubmed

The Structural and Functional Integrity of Rod Photoreceptor Ribbon Synapses Depends on Redundant Actions of Dynamins 1 and 3.

DNM3 DNM1

5.36e-06281238641407
Pubmed

Mutation in the neuronal voltage-gated sodium channel SCN1A in familial hemiplegic migraine.

SCN1A SCN5A

5.36e-06281216054936
Pubmed

Sodium channel expression within chronic multiple sclerosis plaques.

SCN2A SCN8A

5.36e-06281217805013
Pubmed

Comparative structural analysis of human Nav1.1 and Nav1.5 reveals mutational hotspots for sodium channelopathies.

SCN1A SCN5A

5.36e-06281233712547
Pubmed

Missense mutations in sodium channel SCN1A and SCN2A predispose children to encephalopathy with severe febrile seizures.

SCN1A SCN2A

5.36e-06281226311622
Pubmed

Aberrant regulation of a poison exon caused by a non-coding variant in a mouse model of Scn1a-associated epileptic encephalopathy.

SCN1A SCN8A

5.36e-06281233411788
Pubmed

Huntingtin is required for neurogenesis and is not impaired by the Huntington's disease CAG expansion.

FRS2 HTT

5.36e-0628129398841
Pubmed

Inherited neuronal ion channelopathies: new windows on complex neurological diseases.

CACNA1A SCN1A

5.36e-06281219005038
Pubmed

The developmental changes of Na(v)1.1 and Na(v)1.2 expression in the human hippocampus and temporal lobe.

SCN1A SCN2A

5.36e-06281221377452
Pubmed

Reduced release probability prevents vesicle depletion and transmission failure at dynamin mutant synapses.

DNM3 DNM1

5.36e-06281222308498
Pubmed

Direct amplification of a single dissected chromosomal segment by polymerase chain reaction: a human brain sodium channel gene is on chromosome 2q22-q23.

SCN2A SCN7A

5.36e-0628121846440
Pubmed

Persistent Nav1.1 and Nav1.6 currents drive spinal locomotor functions through nonlinear dynamics.

SCN1A SCN8A

5.36e-06281237665666
InteractionSCN11A interactions

CACNA1A NALCN SCN1A SCN5A SCN8A SCN9A SCN10A

6.20e-1415787int:SCN11A
InteractionCACNA1D interactions

CACNA1A NALCN SCN1A SCN5A SCN9A SCN10A

3.52e-1024786int:CACNA1D
InteractionSCN5A interactions

CACNA1A NALCN SCN1A SCN5A SCN8A SCN9A SCN10A

5.49e-1047787int:SCN5A
InteractionSCN1A interactions

CACNA1A NALCN SCN1A SCN5A SCN9A SCN10A

1.22e-0929786int:SCN1A
InteractionNALCN interactions

CACNA1A NALCN SCN1A SCN5A SCN9A

1.49e-0914785int:NALCN
InteractionSCN9A interactions

CACNA1A NALCN SCN1A SCN5A SCN9A

1.48e-0821785int:SCN9A
InteractionSCN10A interactions

CACNA1A SCN1A SCN5A SCN10A

6.71e-0811784int:SCN10A
InteractionCACNA1B interactions

CACNA1A NALCN SCN1A SCN5A SCN9A

3.02e-0737785int:CACNA1B
InteractionSCN8A interactions

SCN4A SCN5A SCN8A FITM2

9.60e-0720784int:SCN8A
InteractionHCST interactions

FOCAD LAPTM4A RHOBTB3 DNM3 RNF213 TSC2 ECPAS EVI5L

1.27e-06205788int:HCST
InteractionSCN4B interactions

SCN1A SCN2A SCN8A

3.08e-068783int:SCN4B
InteractionNEDD4L interactions

BMPR1A SCN1A SCN2A SCN3A SCN5A SCN8A SCN9A SCN10A OCLN

4.00e-06320789int:NEDD4L
InteractionNEDD4 interactions

LAPTM4A BMPR1A FBXL18 SCN1A SCN2A SCN3A SCN5A SCN8A SCN9A SCN10A OCLN

7.60e-065447811int:NEDD4
InteractionCACNA1A interactions

CACNA1A NALCN SCN1A SCN5A SCN9A SCN10A

8.20e-06123786int:CACNA1A
InteractionGPR17 interactions

RNF213 TSC2 CERS6 ECPAS FITM2 SLC29A1 HTT EVI5L

1.37e-05283788int:GPR17
InteractionRHOC interactions

LAPTM4A BMPR1A CMIP RHOBTB3 FRS2 OCLN WLS SLC29A1 HTT ADGRG6 XPR1

1.48e-055847811int:RHOC
InteractionSLC13A3 interactions

FAM209A TSC2 HTT

1.97e-0514783int:SLC13A3
InteractionOR10H1 interactions

FOCAD PIEZO1 ADCY3 SLC29A1

3.85e-0549784int:OR10H1
InteractionSCN4A interactions

SCN4A SCN8A FITM2 SLC29A1 ADGRG6

3.91e-0598785int:SCN4A
InteractionCMKLR1 interactions

DNM3 CERS6 ECPAS FITM2 XPR1

4.52e-05101785int:CMKLR1
InteractionGYPA interactions

FOCAD FAM209A DNM3 TSC2 DNM1 ECPAS

5.83e-05174786int:GYPA
InteractionHTR3A interactions

DHFR2 CERS6 WLS FITM2 SLC29A1

6.23e-05108785int:HTR3A
InteractionGPR182 interactions

FOCAD RHOBTB3 DNM3 RNF213 TSC2 ECPAS WLS HTT XPR1

6.47e-05455789int:GPR182
InteractionTMEM9B interactions

BMPR1A DNM3 RNF213 DNM1 ADCY3

7.10e-05111785int:TMEM9B
InteractionRNF123 interactions

FOCAD UBQLNL SCN3A CAMSAP3 SCN8A FRS2 RNF213 TSC2 ECPAS DNAJA1 BAG6 RYR1

7.31e-058247812int:RNF123
InteractionSIGLECL1 interactions

RNF213 TSC2 OCLN SLC29A1 EVI5L

7.73e-05113785int:SIGLECL1
InteractionCACNA1C interactions

CACNA1A SCN1A SCN5A SCN9A

9.16e-0561784int:CACNA1C
InteractionSLC6A11 interactions

SLC6A11 HTT

1.47e-045782int:SLC6A11
InteractionGET3 interactions

CACNA1A FAM209A DNAJA1 FITM2 BAG6

1.50e-04130785int:GET3
InteractionCLRN2 interactions

FITM2 ADCY3 SLC29A1 ADGRG6

2.16e-0476784int:CLRN2
InteractionFIS1 interactions

FAM209A RNF213 FITM2 BAG6 HTT EVI5L

2.16e-04221786int:FIS1
InteractionULK1 interactions

OCLN WDFY4 ULK2 NLRP3 HTT

2.65e-04147785int:ULK1
CytobandEnsembl 112 genes in cytogenetic band chr2q24

SCN1A SCN2A SCN3A SCN7A SCN9A CERS6

1.09e-07127816chr2q24
Cytoband2q24.3

SCN1A SCN2A CERS6

2.91e-06168132q24.3
Cytoband6p22.2-p21.31

OR12D2 OR12D1

3.06e-0558126p22.2-p21.31
Cytoband2q24

SCN3A SCN9A

1.67e-04118122q24
Cytoband4q21.22

LIN54 TMEM150C

4.11e-04178124q21.22
GeneFamilySodium voltage-gated channel alpha subunits

SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A

3.87e-2095581203
GeneFamilyOlfactory receptors, family 12

OR12D2 OR12D1

2.72e-053552160
GeneFamilyAdhesion G protein-coupled receptors, subfamily G

ADGRG4 ADGRG6

1.89e-047552917
GeneFamilyF-box and leucine rich repeat proteins

FBXL18 KDM2B

1.84e-0321552558
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

CAMSAP3 TSC2 OCLN RYR1

2.23e-03181554694
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HGABA

CACNA1A CMIP NALCN GPR158 SCN1A LIN54 SCN2A SCN3A SCN8A SCN9A DNM3 KDM2B LRRC4B TSC2 ACTL6B CERS6 DNM1 CALN1 CDON XPR1

8.59e-1111068020M39071
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HNBGABA

CACNA1A CMIP NALCN SCN1A SCN2A SCN3A SCN7A SCN8A CTNNA3 SCN9A DNM3 CERS6 WDFY4 CALN1 XPR1

3.04e-097038015M39070
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HDA2

CACNA1A CMIP NALCN SCN2A SCN3A SCN8A SCN9A DNM3 ACTL6B ULK2 CALN1 CDON XPR1

5.07e-095138013M39069
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HDA1

CMIP NALCN SCN2A SCN3A SCN8A SCN9A DNM3 ACTL6B CERS6 MAPK8 DNM1 XPR1

2.03e-075848012M39068
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HSERT

CACNA1A NALCN SCN2A SCN3A SCN7A SCN9A DNM3 ACTL6B XPR1

9.44e-06450809M39072
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HNBML5

CMIP NALCN SCN2A SCN3A SCN8A DNM3 ACTL6B MAPK8 XPR1

1.23e-05465809M39066
CoexpressionZHONG_PFC_C3_ASTROCYTE

CACNA1A SCN3A SCN9A DNM3 DNM1 ULK2 EVI5L XPR1

2.50e-05389808M39102
CoexpressionDESCARTES_ORGANOGENESIS_SENSORY_NEURONS

PDE4A SCN5A SCN7A SCN9A SCN10A

2.87e-05116805MM3649
CoexpressionGSE40273_XBP1_KO_VS_WT_TREG_DN

FMNL3 BMPR1A EVI2A TRRAP WDFY4 CDON

3.35e-05199806M9124
ToppCellprimary_auditory_cortex_(A1C)-Neuronal|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FOCAD CACNA1A GPR158 SCN1A SCN2A SCN3A SCN8A CERS6 DNM1

1.02e-101988196d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FOCAD CACNA1A GPR158 SCN1A SCN2A SCN3A SCN8A CERS6 DNM1

1.02e-101988194ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCellSomatosensory_Cortex_(S1)-Neuronal|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FOCAD CACNA1A SCN1A SCN2A SCN3A SCN8A CERS6 DNM1

2.98e-09198818c01091ef18e096d792ea2a7a715764a5b215355f
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1A SCN1A SCN2A SCN8A ACTL6B DNM1 CALN1

4.60e-081848177d9bcdaff8cbea4c50ab7db0f8e01f6bbd0ef593
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1A SCN1A SCN2A SCN8A ACTL6B DNM1 CALN1

6.37e-081938175fb7808dd971c1cc64c2bd4f8f1de646fb2d77f4
ToppCellMid-temporal_gyrus_(MTG)-Neuronal|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FOCAD GPR158 SCN2A SCN3A SCN8A CERS6 DNM1

7.08e-08196817676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCellNeuronal|World / cells hierarchy compared to all cells using T-Statistic

FOCAD CACNA1A SCN2A SCN3A SCN8A CERS6 DNM1

8.13e-0820081748d801219bc771d6c7e151dc88ca4c179988de85
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1A SCN2A DNM1 WDFY4 CALN1 RYR1

9.54e-071808166ac62bf1251978c8c12e715f7b73144fca619794
ToppCellSubstantia_nigra-Neuronal|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

GPR158 SCN2A CAMSAP3 ACTL6B CERS6 DNM1

1.16e-061868163f889083fcffe516388e9b03a5e23af2010ced33
ToppCellFetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CACNA1A NALCN SCN2A SCN3A SCN8A ACTL6B

1.23e-06188816c4c3b21ab723b0e9beff9ec84f8d68485f771528
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1A SCN1A SCN2A SCN8A DNM1 CALN1

1.27e-06189816f57200c93d39c9bce1adba0a6a1c178c028dd86b
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-4M-Neuronal-ventral_progenitors_and_neurons_1|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.

SCN2A SCN3A SCN9A DNM3 DNM1 CALN1

1.31e-061908166e92c78799f34b31d098854503c796edb0dc7f80
ToppCellPosterior_cortex-Neuronal|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

CMIP SCN2A SCN8A ACTL6B CERS6 DNM1

1.43e-06193816b4989e3436e84dbec3789b46057e0f7a0ebf09d4
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TMEM204 GPR158 LRRC4B WLS ADCY3 ADGRG6

1.48e-061948163cffb5c58f6d5bd254f39ee9c41b7e1e4da0ff75
ToppCellTracheal-10x3prime_v2-Epithelial-Epi_airway_neuro-secretory|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

CACNA1A CLDND2 SCN8A CTNNA3 SCN9A CALN1

1.61e-06197816ff4df77117165b6b25315e29b0722cc136eba607
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GPR158 SCN2A SCN3A SCN8A CERS6 DNM1

1.66e-061988160ff30edfd3c133a42e8cb96e1631a1143215f808
ToppCellNeuron|World / Primary Cells by Cluster

SCN2A SCN3A DNM3 ACTL6B MAPK8 XPR1

1.71e-061998161f8104fd92f04690b41d9d07ac08dc59d76bb97d
ToppCellNeuron-Postmitotic|World / Primary Cells by Cluster

SCN2A SCN3A DNM3 ACTL6B MAPK8 XPR1

1.71e-061998161973527f8a7d4c6490d75c0d0ea153688166a08b
ToppCellMacroglial-Polydendrocytes-PDGFRA-|Macroglial / cells hierarchy compared to all cells using T-Statistic

CACNA1A GPR158 SCN1A SCN2A SCN3A SCN9A

1.76e-06200816f17b5a54e8f9eba9dcd0808ba4e8d275ac41bce2
ToppCellMacroglial-Polydendrocytes-PDGFRA--|Macroglial / cells hierarchy compared to all cells using T-Statistic

CACNA1A GPR158 SCN1A SCN2A SCN3A SCN9A

1.76e-06200816cc3409518f8b436ea92deb955e81114b3f410ff7
ToppCellMacroglial-Polydendrocytes-PDGFRA|Macroglial / cells hierarchy compared to all cells using T-Statistic

CACNA1A GPR158 SCN1A SCN2A SCN3A SCN9A

1.76e-06200816c24a3099e3d96d8b72f6d05286bb355d661a0377
ToppCellMacroglial-Polydendrocytes-PDGFRA---|Macroglial / cells hierarchy compared to all cells using T-Statistic

CACNA1A GPR158 SCN1A SCN2A SCN3A SCN9A

1.76e-062008164fc3de4bff7ed2bf40b38462c4b4e9b87af6a4ca
ToppCellMacroglial-Polydendrocytes-PDGFRA----L1-6|Macroglial / cells hierarchy compared to all cells using T-Statistic

CACNA1A GPR158 SCN1A SCN2A SCN3A SCN9A

1.76e-06200816310cd53db1c137f6af74e6ae682221d7ac27310c
ToppCellMacroglial-Polydendrocytes|Macroglial / cells hierarchy compared to all cells using T-Statistic

CACNA1A GPR158 SCN1A SCN2A SCN3A SCN9A

1.76e-06200816961858738ce35db8760c8c2e136f8369bc444ccf
ToppCellCOVID-19-kidney-Technical/muscle_(EC)|kidney / Disease (COVID-19 only), tissue and cell type

CACNA1A CTNNA3 ADGRG4 CALN1 RYR1

5.56e-0613981564c35411bbe67acb5010dadc4b0b1be0f8b17737
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CACNA1A SCN1A SCN2A SCN3A PKDREJ

9.44e-0615581577fdae85d36efb776db977eb424b32487ef222e4
ToppCellCOVID-19-kidney-Technical/muscle_(Mes)|kidney / Disease (COVID-19 only), tissue and cell type

CACNA1A GPR158 CTNNA3 CALN1 RYR1

1.07e-051598155335cbcdeaf2bbd0268bbfe0e45c8c0d288e640d
ToppCelldroplet-Bladder-nan-3m-Hematologic-leukocyte|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IFI30 EVI2A WDFY4 NLRP3 RYR1

1.20e-051638152f32a9ab0230fdca98ffa7fd59397301d50e4f30
ToppCelldroplet-Bladder-nan-3m-Hematologic|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IFI30 EVI2A WDFY4 NLRP3 RYR1

1.20e-051638156c2967dee563295febe2adabf503d095cb911ccf
ToppCellfacs-Heart-RA-24m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCN4A IFI30 EVI2A WDFY4 RYR1

1.28e-0516581536415924d05373e9dd3665be599f4f3f40bf0497
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Dendritic-CD1c-positive_myeloid_dendritic_cell-DC2_(CD1c+_dendritic_cell)-DC2_L.1.2.1.3|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SCN9A KDM2B WDFY4 ADCY3 HTT

1.28e-0516581576abebe80e5f8bf44825bb619ae86fcb6f66ffeb
ToppCellfacs-Heart-RA-24m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCN4A IFI30 EVI2A WDFY4 RYR1

1.28e-0516581556310fddd3d8e4afdfde066d26cee9747e5b8c6a
ToppCelldroplet-Bladder-nan-24m-Hematologic-granulocyte-monocyte_progenitor|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EVI2A WDFY4 ZAP70 NLRP3 RYR1

1.39e-05168815c6e0daa790dd5db20dd1ab8c1e7142484976d743
ToppCellfacs-Heart-RA-24m-Lymphocytic|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCN4A IFI30 WDFY4 ZAP70 RYR1

1.43e-05169815dcf92121fb00e3b6498e2648363e90ac044ea396
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GLDC SCN2A SCN3A SCN7A PKDREJ

1.43e-051698150332f539a2f7d6dcd081a5d2f567290721f5a329
ToppCelldroplet-Thymus-nan-21m-Myeloid-professional_antigen_presenting_cell|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNM3 IFI30 EVI2A WDFY4 RYR1

1.47e-0517081529deb285d5a82c0abcc108012ca42f4b4b4d9e19
ToppCelldroplet-Thymus-nan-21m-Myeloid|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNM3 IFI30 EVI2A WDFY4 RYR1

1.47e-05170815dc35d66a9a9fe6cdd7f4ec0fe7efa49d02f2b5b2
ToppCelldroplet-Trachea-3m-Hematologic-myeloid-tracheal_macrophage-macrophage_of_tracheal_l15|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

IFI30 EVI2A WDFY4 NLRP3 RYR1

1.52e-0517181587cb65648c663e246f94cea1a5ed12e8e29ec629
ToppCelldroplet-Lung-3m-Hematologic-myeloid-myeloid_dendritic_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

IFI30 KDM2B EVI2A WDFY4 RYR1

1.60e-05173815f66aebceb3eb389bc5ff6c0b398d6f4e9959a14f
ToppCellfacs-Thymus-Thymus_Flowthrough-18m-Myeloid-macrophage|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNM3 IFI30 EVI2A WDFY4 RYR1

1.65e-051748152f4bc0275cbcaa830d04a4c76e042456908d2277
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-Myeloid_Dendritic_Type_1|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1A KDM2B EVI2A RYR1 EVI5L

1.65e-05174815ff13a5c55d18b951315908f33cb47c7f9cb901bf
ToppCellfacs-Thymus-Thymus_Flowthrough-18m-Myeloid|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNM3 IFI30 EVI2A WDFY4 RYR1

1.65e-0517481501eff218e71a04201189a0313aaf91437fffed95
ToppCellfacs-Thymus-Thymus_Flowthrough-18m-Myeloid-macrophage|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNM3 IFI30 EVI2A WDFY4 RYR1

1.65e-05174815f0f6d135e1fb4c15022be103b00d8d5456515a18
ToppCell3'-Child04-06-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CACNA1A SCN2A SCN3A ADGRG4 CDON

1.65e-05174815a62531ebf16b32b249168dca11b870f63a8aa81c
ToppCelldroplet-Bladder-nan-24m-Hematologic-nan|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCN4A IL21 EVI2A ZAP70 RYR1

1.74e-051768150089b50d607f4d2f18639fab0f3fc779227baa7a
ToppCell10x5'-GI_large-bowel-Mast|GI_large-bowel / Manually curated celltypes from each tissue

LAPTM4A BMPR1A CLDND2 RHOBTB3 SCN7A

1.84e-05178815d10ed2543c96e1a2373f847e0b82144771e26d07
ToppCell10x5'-GI_large-bowel-Mast-Mast_cells|GI_large-bowel / Manually curated celltypes from each tissue

LAPTM4A BMPR1A CLDND2 RHOBTB3 SCN7A

1.84e-051788158fc5f735afa25ae43c2acb1c710ade6e9e093e3c
ToppCellEpithelial-lung_neuroendocrine_cell_(PNEC)|World / Lineage, Cell type, age group and donor

CACNA1A NALCN SCN2A SCN3A SCN8A

2.05e-0518281557bf4ffb304324e2e392e196336a530d9f78fe0d
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GLDC RHOBTB3 SCN2A SCN3A SCN7A

2.05e-051828155f513bbb7125956eb528e3120de3fd776770a7c3
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NALCN RHOBTB3 CTNNA3 LRRC4B ADGRG6

2.10e-0518381512daaea821e49bc94a01e2496331e92a80d27339
ToppCell5'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_A-Branch_A3_(IPAN/IN)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GPR158 SCN2A SCN9A ACTL6B XPR1

2.27e-0518681518fd311252299d6d30ddb32002ed069056108206
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

CMIP SCN2A SCN10A IFI30 CALN1

2.27e-0518681523b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCellSubstantia_nigra-Neuronal-Inhibitory|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

GPR158 CAMSAP3 SCN9A CERS6 DNM1

2.27e-051868159d3efe2a4feea2bc205a7e45b9b9f9ed9b3609ce
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1A SCN1A SCN2A SCN8A DNM1

2.27e-051868157278a1a1bf9bb27aeb03852134defb31b62f30d6
ToppCellTCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Lobular_Carcinoma-6|TCGA-Breast / Sample_Type by Project: Shred V9

FMNL3 TMEM204 SCN7A LRRC4B NLRP3

2.39e-05188815c90669b51e1902fe7726555290c91c92a911df83
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

GPR158 SCN2A SCN3A CAMSAP3 SCN9A

2.39e-05188815b73e8a40393c3f656e2fcfe395a761b1f985c254
ToppCellPCW_07-8.5-Epithelial-Epithelial_alveolar-distal-epi_SFTPC^high_distal_(9)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

GLDC CAMSAP3 CTNNA3 UGT2B17 OCLN

2.45e-051898155d9da836ce4308b8458bb3be3871a0aca734b6cd
ToppCellChildren_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

KLF6 SCN9A WLS NLRP3 RYR1

2.52e-051908152d54fca50593fbd11fe13fc2bfaf937a05db776d
ToppCellGlobus_pallidus-Neuronal|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

GPR158 SCN2A CAMSAP3 SCN8A DNM1

2.52e-05190815416de85d8841dac883faa6f5339b2fb461a09e82
ToppCell15-Trachea-Epithelial-Neuroendocrine|Trachea / Age, Tissue, Lineage and Cell class

CACNA1A SCN2A SCN3A SCN9A ACTL6B

2.58e-0519181576311fa5f3ae9bb27cf04387a8c92300f2888c28
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1A SCN1A SCN2A SCN8A DNM1

2.71e-05193815be28070c049e7cb68bcd54f582226eb2f5e4bc1c
ToppCell3'-Distal_airway-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TMEM204 GPR158 WLS ADCY3 ADGRG6

2.71e-05193815b2abe939027a69b60d83a28d4d4cc53ba1dee4c5
ToppCell3'-Distal_airway-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TMEM204 GPR158 WLS ADCY3 ADGRG6

2.71e-05193815d75f334fe3d9f39ef02a5de0f8202f7a761a8fc8
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

KLF6 GLDC DNM3 OCLN DNAH5

2.71e-05193815f42a0f02ed00fe1bb833ff0a0640d9131bca89bd
ToppCell3'-Distal_airway-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TMEM204 GPR158 WLS ADCY3 ADGRG6

2.71e-0519381541ea268e7697101fe70d8ef1045f3a43b9311739
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1A SCN1A SCN2A SCN8A DNM1

2.71e-051938150c652ebe22ce5d2927599dd97ef1920547858395
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1A SCN1A SCN2A SCN8A DNM1

2.71e-051938158689a70a33a7c3823dc647d41ac0160e7c3ae396
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

KLF6 GLDC DNM3 OCLN DNAH5

2.71e-0519381542df7ed37d11fb542b4d1d714b6f87ae8e1396a6
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

KLF6 DNM3 RNF213 OCLN DNAH5

2.78e-05194815e577d9e88390b36b5a09b97fe1026089892275a3
ToppCellHippocampus-Neuronal|Hippocampus / BrainAtlas - Mouse McCarroll V32

PDE4A GPR158 SCN2A SCN8A DNM1

2.78e-051948158aeb347b3024354c9505f4f0fddf0b843489dc6b
ToppCell3'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LAPTM4A CMIP TMEM204 RHOBTB3 TMEM150C

2.85e-05195815bad7f2162000f29488b3c4b903dcac9a818621f7
ToppCellcellseq-Mesenchymal-Myocytic-Myocytic_1|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

TMEM204 LRRC4B WLS ADCY3 ADGRG6

2.92e-05196815c373465e34e2dd581247962d59e0477aae877079
ToppCellcellseq-Mesenchymal-Myocytic-Myocytic_1-Pericyte|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

TMEM204 LRRC4B WLS ADCY3 ADGRG6

2.92e-051968158b5337ccf74de90e8b89a02ac00671af1de2cfff
ToppCellHealthy_donor-cDC|World / disease group, cell group and cell class (v2)

SCN9A IFI30 WDFY4 RYR1 ADGRG6

2.99e-05197815a545fe3a80cd721bf01115bbb645753840ec9f40
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_neuro-secretory-Neuroendocrine|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CACNA1A SCN2A SCN3A SCN8A CTNNA3

3.07e-051988158f25e8dff42bad8e779ca618bdb1cb1610667962
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FOCAD SCN1A SCN2A SCN8A DNM1

3.07e-051988158ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCellBronchial-NucSeq-Immune_Myeloid-Macrophage_other-Macrophage_intravascular|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SCN9A DNM1 WDFY4 NLRP3 RYR1

3.07e-05198815c7dbf24caae5c4ef285845d13055de9e07281bb3
ToppCellnormal_Lung-Myeloid_cells-mo-Mac|Myeloid_cells / Location, Cell class and cell subclass

KLF6 RHOBTB3 SCN9A WLS ADGRG6

3.07e-05198815fbd72ebaba73cc30e79dc8a8c3d46b6f863c1494
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_neuro-secretory|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CACNA1A SCN2A SCN3A SCN8A CTNNA3

3.07e-05198815e3e0aa3ef20b2370f5b133048510677aaa562dfa
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Layer_IV-2|World / Primary Cells by Cluster

CMIP SCN2A SCN9A DNM3 XPR1

3.14e-05199815f09b40245d3d826275bbe5f508dedccc75a911bd
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Layer_IV|World / Primary Cells by Cluster

CMIP SCN2A SCN9A DNM3 XPR1

3.14e-05199815e45448ec4db8875c8aaa9aad109a10e2905a4226
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

FMNL3 KLF6 RNF213 NLRP3 RYR1

3.14e-05199815e7faf7d0cb43cf93149c446e5f718f84fa85477c
ToppCellFrontal_cortex-Neuronal|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

CMIP SCN2A ACTL6B MAPK8 DNM1

3.14e-05199815f88039d862f3bfa01dc39d2de4f3f548dc5a0e61
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Upper_Layer|World / Primary Cells by Cluster

SCN2A SCN3A SCN9A DNM3 CALN1

3.22e-05200815db10f76938af553d1a2275bb02ef75dff3c3135b
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Upper_Layer-21|World / Primary Cells by Cluster

SCN2A SCN3A SCN9A DNM3 CALN1

3.22e-0520081530a3e4aee12ec1b5acdce90f86c9733c27a7f6fc
ToppCelldistal-mesenchymal-Pericyte-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

TMEM204 GPR158 RHOBTB3 WLS ADGRG6

3.22e-05200815867935701fac71a3fe01578362da0676f959736c
ToppCellBrain_organoid-organoid_Tanaka_cellReport-10w-Neuronal-Cortical_neuron|10w / Sample Type, Dataset, Time_group, and Cell type.

SCN2A SCN3A DNM3 ACTL6B XPR1

3.22e-0520081568c90376e2779434e4ad8dc6dd3b44baa700e2f4
ToppCelldistal-2-mesenchymal-Pericyte|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

GPR158 RHOBTB3 SCN7A WLS ADGRG6

3.22e-052008154ee0b2f56c2652435fa78bf6b3c90cea28df74e0
ToppCellCOVID-19-kidney-Epithelial_Doublet|kidney / Disease (COVID-19 only), tissue and cell type

CACNA1A CTNNA3 WDFY4 RYR1

7.76e-05124814d6f59ddb9b9df02b5201f23fa5fb78f3fd891ee9
ToppCell390C-Epithelial_cells-Epithelial-B_(AT2)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

SLC10A2 TMEM204 SCN3A

9.76e-05498131002c6f5cfc09eb5cf882e0cf366d9ba8e456a57
ToppCell390C-Epithelial_cells-Epithelial-B_(AT2)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

SLC10A2 TMEM204 SCN3A

9.76e-0549813d7fc93efa70b464da39192e4bd8b1e8ad19bbec1
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A11 SCN1A SCN9A SCN10A

1.42e-0414581496712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCellCOVID-19-kidney-Technical/muscle_(PCT)|kidney / Disease (COVID-19 only), tissue and cell type

CACNA1A SCN1A CTNNA3 CALN1

1.46e-04146814c55f1bdb6ac43b4118cb27ea7c879527e1afcbab
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CACNA1A UGT2B17 DNM1 ADGRG6

1.58e-04149814cc6224c6b79f43b97adc1ce48ca4906bff2ad318
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-NP-L5_NP_ALM_Trhr_Nefl|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

LAPTM4A MC3R WLS CDON

1.58e-04149814558a441804dbcd5b5f39a3b1933b48976711ff15
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CACNA1A UGT2B17 DNM1 ADGRG6

1.58e-0414981424a7538b54b2a5291503c7493fefed4e45e8d710
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SCN1A SCN2A SCN7A ACTL6B

1.66e-04151814f41c6558a5874b6464c157027fdf202257c60e5b
ToppCellPND14-Immune-Immune_Myeloid-DC-cDC2-cDC2_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

IFI30 EVI2A WDFY4 RYR1

1.70e-04152814b2e29fbda6b5f2d87cfc05423caf9cbf3b04ac65
ToppCell343B-Myeloid-Dendritic-cDC1|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

SCN3A DNM3 WDFY4 ADGRG6

1.79e-0415481471d33b5dbfab5820e3daddb01806a69116ba8008
ToppCellfacs-Marrow-T-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCN9A SCN10A PKDREJ DNAH5

1.97e-04158814f296ca24fdedc33f1d24b79e7660763114ce7fa3
DrugAPETx1, Anthopleura elegantissima

SCN2A SCN3A SCN4A SCN8A SCN10A

2.82e-126805ctd:C475726
DrugZonisamide

SCN1A SCN2A SCN3A SCN4A SCN5A SCN9A

1.87e-1117806DB00909
DrugNSC7524

CACNA1A SLC6A11 SCN2A SCN3A SCN4A SCN5A SCN7A SCN9A SCN10A ADCY3 RYR1

4.08e-111828011CID000005657
Druglamotrigine

CACNA1A SCN2A SCN3A SCN4A SCN5A SCN7A SCN9A SCN10A RYR1

2.89e-10116809CID000003878
DrugAC1L1MOZ

SCN3A SCN4A SCN5A SCN7A SCN9A SCN10A

4.34e-1027806CID000031958
Drugbepridil

CACNA1A SCN3A SCN4A SCN5A SCN7A SCN9A SCN10A CALN1 RYR1

6.07e-10126809CID000002351
Drugtocainide

SCN3A SCN4A SCN5A SCN7A SCN9A SCN10A

8.63e-1030806CID000038945
Drugbenzocaine

SCN2A SCN3A SCN4A SCN7A SCN9A SCN10A

3.31e-0937806CID000002337
Drugdibucaine

SCN3A SCN4A SCN5A SCN7A SCN9A SCN10A CALN1

4.13e-0968807CID000003025
Drugdiprafenone

SCN3A SCN4A SCN7A SCN9A SCN10A

5.28e-0919805CID000071249
Drugflecainide

SCN3A SCN4A SCN5A SCN7A SCN9A SCN10A RYR1

5.61e-0971807CID000003355
Druggabapentin

CACNA1A SLC6A11 SCN3A SCN4A SCN5A SCN7A SCN9A SCN10A RYR1

8.15e-09169809CID000003446
Drug2,3,5,6-tetrafluoro-4-methylbenzyl (Z)-(1RS)-cis-3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropanecarboxylate

SCN2A SCN3A SCN8A SCN10A

9.79e-098804ctd:C489827
Drugpilsicainide

SCN3A SCN4A SCN5A SCN7A SCN9A SCN10A

1.30e-0846806CID000004820
Drugspiradoline

SCN3A SCN4A SCN7A SCN9A SCN10A FRS2

1.30e-0846806CID000005620
DrugSodium

SLC6A11 SCN2A SCN3A SCN5A SCN8A SCN9A SCN10A

1.84e-0884807ctd:D012964
DrugAC1NT1AF

SCN3A SCN4A SCN7A SCN9A SCN10A

2.37e-0825805CID005322157
DrugPirmenolum

SCN3A SCN4A SCN7A SCN9A SCN10A

2.93e-0826805CID000004853
DrugPbTx-1

SCN3A SCN4A SCN7A SCN9A SCN10A

3.58e-0827805CID006437089
Drugnefopam

SCN3A SCN4A SCN7A SCN9A SCN10A

3.58e-0827805CID000004450
DrugN-(2-methyl-3-(4-(4-(4-(trifluoromethoxy)benzyloxy)piperidin-1-yl)-1,3,5-triazin-2-ylamino)phenyl)acetamide

SCN3A SCN4A SCN9A

4.18e-083803ctd:C561228
Drugparaben

SCN3A SCN4A SCN7A SCN9A SCN10A

4.35e-0828805CID000007175
Drugisradipine

CACNA1A SCN3A SCN4A SCN7A SCN9A SCN10A RYR1

6.23e-08100807CID000003784
Drugprocaine

CACNA1A SLC10A2 SCN3A SCN4A SCN7A SCN9A SCN10A RYR1

6.66e-08153808CID000004914
DrugTetracaine

SCN9A SCN10A MAPK8 RYR1

6.85e-0812804ctd:D013748
Drugphenytoin

CACNA1A SCN2A SCN3A SCN4A SCN5A SCN7A SCN9A SCN10A RYR1

7.67e-08219809CID000001775
Drugzonisamide

SLC6A11 SCN3A SCN4A SCN7A SCN9A SCN10A

8.17e-0862806CID000005734
DrugNSC93767

SCN3A SCN4A SCN7A SCN9A SCN10A

8.82e-0832805CID000005658
Druglidocaine

SCN3A SCN4A SCN5A SCN7A SCN9A SCN10A ADCY3 RYR1

9.42e-08160808CID000003676
Drugsaxitoxin

SCN2A SCN3A SCN4A SCN7A SCN9A SCN10A

1.09e-0765806CID000037165
DrugAC1L1CQC

SCN3A SCN4A SCN5A SCN7A SCN9A SCN10A

1.09e-0765806CID000002012
Drugmexiletine

SCN3A SCN4A SCN5A SCN7A SCN9A SCN10A

1.19e-0766806CID000004178
Drugdisopyramide

SCN3A SCN4A SCN5A SCN7A SCN9A SCN10A

1.19e-0766806CID000003114
Drug5-hydroxypropafenone

SCN3A SCN4A SCN7A SCN9A SCN10A

1.21e-0734805CID000107927
DrugLidocaine

SCN5A SCN9A SCN10A

1.67e-074803DB00281
DrugAPETx2 protein, Anthopleura elegantissima

SCN2A SCN8A SCN10A

1.67e-074803ctd:C501880
Drugriluzole

CACNA1A SCN3A SCN4A SCN5A SCN7A SCN9A SCN10A RYR1

1.80e-07174808CID000005070
Drugaprindine

SCN3A SCN4A SCN7A SCN9A SCN10A

2.16e-0738805CID000002218
Drugcarbamazepine

SCN2A SCN3A SCN4A SCN5A SCN7A SCN9A SCN10A ADCY3

2.23e-07179808CID000002554
DrugTetrodotoxin

SCN2A SCN3A SCN5A SCN8A SCN9A

2.82e-0740805ctd:D013779
DrugS-ropivacaine

SCN3A SCN4A SCN7A SCN9A SCN10A

2.82e-0740805CID000071273
Drugtetradotoxin

CACNA1A SLC6A11 KLF6 SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A SCN9A SCN10A

2.98e-074288011CID000020382
DrugScorpion Venoms

SCN2A SCN3A SCN4A SCN9A

4.16e-0718804ctd:D012604
Drugclenbuterol

SCN3A SCN4A SCN7A SCN9A SCN10A IFI30 ADCY3

6.87e-07142807CID000002783
Drugindoxacarb

SCN3A SCN4A SCN7A SCN9A SCN10A

7.97e-0749805CID000107720
Drugsalbutamol

PDE4A SCN3A SCN4A SCN7A SCN9A SCN10A ADCY3

8.29e-07146807CID000002083
Drugfenpropathrin

SCN2A SCN3A SCN10A

8.29e-076803ctd:C044267
DrugGTP[S]

CACNA1A SCN3A SCN4A SCN7A SCN9A SCN10A DNM3 ACTL6B DNM1 ZP3 ADCY3 RYR1

1.01e-065918012CID000001764
Drugpropafenone

SCN3A SCN4A SCN5A SCN7A SCN9A SCN10A

1.27e-0698806CID000004932
DrugAC1NSN3X

SCN3A SCN4A SCN7A SCN9A SCN10A

1.30e-0654805CID005366189
Drugtrimethoprim

SCN3A SCN4A SCN7A DHFR2 SCN9A SCN10A

1.34e-0699806CID000005578
Drugtriamterene

SCN3A SCN4A SCN7A SCN9A SCN10A

1.87e-0658805CID000005546
Drugpyraclofos

CACNA1A SCN2A SCN4A SCN5A SCN7A SCN9A

2.01e-06106806CID000093460
DrugAC1OAGFB

SCN3A SCN4A SCN7A SCN9A SCN10A DNM3 ACTL6B DNM1 TRRAP ADCY3 ZAP70

2.83e-065398011CID006857345
Drugcyclaine

SCN5A SCN10A IFI30

3.46e-069803CID000010770
DrugMexiletine

SCN5A SCN9A SCN10A

3.46e-069803ctd:D008801
Drugresiniferatoxin

SCN3A SCN4A SCN7A SCN9A SCN10A

3.57e-0666805CID000104826
Drugisoproterenol

CACNA1A PDE4A SCN3A SCN4A SCN5A SCN7A SCN9A SCN10A ACTL6B MAPK8 ADCY3 RYR1

3.64e-066698012CID000003779
Drughydrochlorothiazide

SCN3A SCN4A SCN7A SCN9A SCN10A ADCY3

4.13e-06120806CID000003639
DrugGBR 12909

SCN3A SCN4A SCN7A SCN9A SCN10A

4.45e-0669805CID000003455
DrugT2755

SCN3A SCN4A SCN7A SCN9A SCN10A

5.12e-0671805CID000005514
Drugbupivacaine

SCN3A SCN4A SCN7A SCN9A SCN10A HTT

5.23e-06125806CID000002474
Drug1, 3-diallylurea

SCN3A SCN4A SCN7A SCN9A SCN10A

6.29e-0674805CID000074537
Drugimide

SCN3A SCN4A SCN7A SCN9A SCN10A

6.29e-0674805CID000443040
Drugdiphenhydramine

SCN3A SCN4A SCN7A SCN9A SCN10A

6.72e-0675805CID000003100
Drugsipatrigine

SLC6A11 SCN2A SCN4A SCN9A

8.54e-0637804CID000060803
Drugbupropion

SCN3A SCN4A SCN7A SCN9A SCN10A

9.81e-0681805CID000000444
Drugmu-conotoxin KIIIA, Conus kinoshitai

SCN2A SCN4A

1.22e-052802ctd:C502265
DrugHexylcaine

SCN5A SCN10A

1.22e-052802DB00473
DrugRanolazine

SCN5A SCN9A

1.22e-052802DB00243
DrugPhenytoin

SCN1A SCN5A

1.22e-052802DB00252
DrugFlecainide

SCN4A SCN5A

1.22e-052802DB01195
Drugdecamethrin

SCN1A SCN2A SCN3A SCN8A SCN10A MAPK8

1.28e-05146806ctd:C017180
Drugamiodarone

SCN3A SCN4A SCN5A SCN7A SCN9A SCN10A

2.14e-05160806CID000002156
Drugsodium

SLC6A11 SLC10A2 SCN2A SCN3A SCN4A SCN5A SCN7A SCN9A SCN10A ACTL6B ADCY3 SLC29A1 RYR1

2.36e-059448013CID000000923
Drugmoricizine

SCN4A SCN5A SCN9A

3.28e-0518803CID000034632
DrugDibucaine

SCN5A SCN10A

3.65e-053802DB00527
Drugfenfluramine

SCN3A SCN4A SCN7A SCN9A MC3R SCN10A

3.91e-05178806CID000003337
Drugtriphosphoinositide

SCN3A SCN4A SCN7A SCN9A SCN10A ACTL6B TRRAP

4.97e-05273807CID009543520
Drugverapamil

CACNA1A SCN3A SCN4A SCN5A SCN7A SCN9A SCN10A ADCY3 RYR1

5.51e-05490809CID000002520
Drugetorphine

CACNA1A DNM3 DNM1 ADCY3

5.55e-0559804CID000026721
Drugprocainamide

SCN3A SCN4A SCN5A SCN7A SCN9A SCN10A

5.62e-05190806CID000004913
Drugpropofol

SCN3A SCN4A SCN7A SCN9A SCN10A RYR1

5.78e-05191806CID000004943
DrugNSC759256

CACNA1A SLC6A11 IL21 RYR1

7.19e-0563804CID000125889
DrugFospropofol

SCN2A SCN4A

7.28e-054802DB06716
DrugPropofol

SCN2A SCN4A

7.28e-054802DB00818
Drugmibefradil

CACNA1A SCN5A SCN9A RYR1

7.65e-0564804CID000060662
DrugMulticide

SCN2A SCN4A SCN9A

9.09e-0525803CID000024365
Drugsynthetic pyrethrins

CACNA1A SCN4A SCN9A ADCY3

1.15e-0471804CID000002982
Drugquindine

SCN3A SCN4A SCN5A SCN7A SCN9A SCN10A

1.23e-04219806CID000001065
Drugencainide

SCN4A SCN5A SCN9A

1.28e-0428803CID000048040
DrugDPI 201-106

SCN4A SCN5A SCN9A

1.28e-0428803CID000005190
Drugisofagomine

SCN4A SCN5A SCN9A SCN10A

1.42e-0475804CID000447607
Drugcyfluthrin

SCN2A SCN3A SCN10A

1.43e-0429803ctd:C052570
Drugoxcarbazepine

SCN4A SCN5A SCN9A

1.58e-0430803CID000034312
Drugpseudococaine

SLC6A11 SCN3A SCN4A SCN5A SCN7A SCN9A SCN10A ACTL6B ADCY3

1.73e-04570809CID000002826
Drugforskolin from Coleus forskohlii

PDE4A KLF6 SCN3A SCN4A SCN7A SCN9A MC3R SCN10A ACTL6B MAPK8 ADCY3 RYR1

2.08e-0410138012CID000003413
DrugNSC15627

SCN4A SCN5A SCN9A

2.31e-0434803CID000002073
Drugtrans-permethrin

SCN4A SCN9A ADCY3 RYR1

2.41e-0486804CID000040159
Drugdihydrochloride

SCN3A SCN4A SCN7A SCN9A SCN10A

2.46e-04159805CID000070978
Diseasegeneralized epilepsy with febrile seizures plus 2 (implicated_via_orthology)

SCN1A SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A SCN9A SCN10A

4.96e-2310809DOID:0111294 (implicated_via_orthology)
DiseaseDravet syndrome (implicated_via_orthology)

SCN1A SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A SCN9A SCN10A

4.96e-2310809DOID:0080422 (implicated_via_orthology)
Diseasegeneralized epilepsy with febrile seizures plus (implicated_via_orthology)

SCN1A SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A SCN9A SCN10A

1.09e-2112809DOID:0060170 (implicated_via_orthology)
Diseaseepilepsy (implicated_via_orthology)

CACNA1A SCN1A SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A SCN9A SCN10A

2.37e-111638010DOID:1826 (implicated_via_orthology)
Diseaseanxiety disorder (implicated_via_orthology)

SCN1A SCN2A SCN3A SCN9A TSC2

3.28e-0922805DOID:2030 (implicated_via_orthology)
DiseaseEpilepsy

SCN1A SCN2A SCN8A SCN9A TSC2 DNM1

5.32e-07109806C0014544
DiseaseGeneralized Epilepsy with Febrile Seizures Plus

SCN1A SCN2A SCN9A

1.59e-069803C3502809
DiseaseEpilepsy, Cryptogenic

SCN1A SCN2A SCN8A TSC2 DNM1

2.99e-0682805C0086237
DiseaseAwakening Epilepsy

SCN1A SCN2A SCN8A TSC2 DNM1

2.99e-0682805C0751111
DiseaseAura

SCN1A SCN2A SCN8A TSC2 DNM1

2.99e-0682805C0236018
DiseaseInfantile Severe Myoclonic Epilepsy

SCN1A SCN2A SCN9A

5.38e-0613803C0751122
DiseaseEarly Infantile Epileptic Encephalopathy 6

SCN1A SCN9A

7.26e-062802C4551549
DiseaseEarly infantile epileptic encephalopathy with suppression bursts

SCN1A SCN2A DNM1

1.05e-0516803C0393706
DiseaseB Virus Infection

SCN8A SCN9A

2.17e-053802C0037140
DiseaseBenign familial infantile epilepsy

SCN2A SCN8A

2.17e-053802cv:C5575231
DiseasePostherpetic neuralgia

SCN8A SCN9A

2.17e-053802C0032768
DiseaseHerpesviridae Infections

SCN8A SCN9A

2.17e-053802C0019372
DiseasePrimary Erythermalgia

SCN9A SCN10A

2.17e-053802C0014805
DiseaseFamilial or sporadic hemiplegic migraine

CACNA1A SCN1A

2.17e-053802cv:CN295307
DiseaseFamilial hemiplegic migraine

CACNA1A SCN1A

2.17e-053802cv:C0338484
DiseasePAROXYSMAL EXTREME PAIN DISORDER

SCN9A SCN10A

2.17e-053802C1833661
Diseaseintestinal disease (is_implicated_in)

BMPR1A SLC10A2

2.17e-053802DOID:5295 (is_implicated_in)
DiseaseBrugada ECG Pattern

SCN5A SCN10A

4.34e-054802C1721096
Diseasecardiovascular age measurement

SCN5A CTNNA3 SCN10A

6.66e-0529803EFO_0803380
Diseasecentronuclear myopathy 1 (implicated_via_orthology)

DNM3 DNM1

7.22e-055802DOID:0111223 (implicated_via_orthology)
Diseasemicrocytic anemia (implicated_via_orthology)

DNM3 DNM1

7.22e-055802DOID:11252 (implicated_via_orthology)
DiseaseCharcot-Marie-Tooth disease dominant intermediate B (implicated_via_orthology)

DNM3 DNM1

7.22e-055802DOID:0110197 (implicated_via_orthology)
DiseaseEpileptic encephalopathy

CACNA1A ACTL6B DNM1

7.39e-0530803C0543888
DiseaseEPILEPTIC ENCEPHALOPATHY, EARLY INFANTILE, 1

SCN1A DNM1

1.08e-046802C3463992
DiseaseLennox-Gastaut syndrome

SCN1A DNM1

1.08e-046802C0238111
DiseaseFamilial benign neonatal epilepsy

SCN2A SCN8A

1.08e-046802C0220669
DiseaseNeurodevelopmental Disorders

SCN1A SCN2A SCN8A DNM1

1.22e-0493804C1535926
DiseaseSeizure, Febrile, Simple

SCN1A SCN2A

1.51e-047802C0149886
DiseaseSeizure, Febrile, Complex

SCN1A SCN2A

1.51e-047802C0751057
Diseaseelectrocardiography, PR interval

SCN5A SCN10A

1.51e-047802EFO_0004327, EFO_0004462
DiseaseCongenital Pain Insensitivity

SCN9A SCN10A

1.51e-047802C0002768
DiseaseHereditary Sensory Autonomic Neuropathy, Type 5

SCN9A SCN10A

1.51e-047802C0020075
DiseaseEarly Childhood Epilepsy, Myoclonic

SCN1A SCN9A

2.01e-048802C0393695
DiseaseIdiopathic Myoclonic Epilepsy

SCN1A SCN9A

2.01e-048802C0338478
DiseaseSymptomatic Myoclonic Epilepsy

SCN1A SCN9A

2.01e-048802C0338479
DiseaseX-linked infantile spasms

SCN1A DNM1

2.01e-048802C4552072
DiseaseBenign Infantile Myoclonic Epilepsy

SCN1A SCN9A

2.01e-048802C0751120
DiseaseMyoclonic Encephalopathy

SCN1A SCN9A

2.01e-048802C0438414
DiseaseMyoclonic Absence Epilepsy

SCN1A SCN9A

2.01e-048802C0393703
DiseaseQRS complex, QRS duration

FMNL3 SCN5A SCN10A

2.51e-0445803EFO_0005054, EFO_0005055
DiseaseFebrile Convulsions

SCN1A SCN2A

2.58e-049802C0009952
DiseaseMyoclonic Epilepsy

SCN1A SCN9A

2.58e-049802C0014550
Diseasesupraventricular ectopy

SCN5A SCN10A

2.58e-049802EFO_0009277
DiseaseEpilepsy, Myoclonic, Infantile

SCN1A SCN9A

3.22e-0410802C0917800
DiseaseIGF-1 measurement

PDE4A CMIP TMEM204 LIN54 MC3R UGT2B17 ULK2

3.64e-04488807EFO_0004627
Diseasequality of life during menstruation measurement, acne

FMNL3 CALN1

3.93e-0411802EFO_0003894, EFO_0009366
DiseaseMyoclonic Astatic Epilepsy

SCN1A SCN9A

3.93e-0411802C0393702
DiseaseHuntington Disease, Late Onset

SLC29A1 HTT

4.71e-0412802C0393574
Diseasecollagen disease (implicated_via_orthology)

DNM3 DNM1

4.71e-0412802DOID:854 (implicated_via_orthology)
DiseaseAkinetic-Rigid Variant of Huntington Disease

SLC29A1 HTT

4.71e-0412802C0751207
DiseaseJuvenile Huntington Disease

SLC29A1 HTT

4.71e-0412802C0751208
DiseaseCongenital myopathy (disorder)

SCN4A RYR1

4.71e-0412802C0270960
DiseaseBrugada Syndrome 1

SCN5A SCN10A

5.55e-0413802C4551804
Diseasedevelopmental and epileptic encephalopathy (implicated_via_orthology)

DNM3 DNM1

5.55e-0413802DOID:0112202 (implicated_via_orthology)
DiseaseT wave morphology measurement

SCN5A SCN10A

6.47e-0414802EFO_0008398
DiseaseConventional (Clear Cell) Renal Cell Carcinoma

BMPR1A TSC2 MAPK8 RYR1

7.15e-04148804C0279702
DiseaseAutistic Disorder

PDE4A SCN7A TSC2 TRRAP WDFY4

7.30e-04261805C0004352
DiseaseMMR-related febrile seizures

SCN1A SCN2A

7.45e-0415802EFO_0006519
DiseaseP wave duration

SCN5A SCN10A

7.45e-0415802EFO_0005094
DiseaseNeuralgia, Supraorbital

SCN9A SCN10A

8.50e-0416802C0038870
DiseaseTremor, Rubral

CACNA1A SCN8A

8.50e-0416802C0750940
DiseaseAtaxia, Appendicular

CACNA1A SCN8A

8.50e-0416802C0750937
DiseaseNeuralgia

SCN9A SCN10A

8.50e-0416802C0027796
DiseaseAtaxia, Motor

CACNA1A SCN8A

8.50e-0416802C0278161
DiseaseRomano-Ward Syndrome

SCN5A SCN10A

8.50e-0416802C0035828
DiseaseNeuralgia, Atypical

SCN9A SCN10A

8.50e-0416802C0234247
DiseaseNeuralgia, Stump

SCN9A SCN10A

8.50e-0416802C0234249
DiseaseAtaxia, Sensory

CACNA1A SCN8A

8.50e-0416802C0240991
DiseaseNeuralgia, Iliohypogastric Nerve

SCN9A SCN10A

8.50e-0416802C0423712
DiseaseNeuralgia, Perineal

SCN9A SCN10A

8.50e-0416802C0423711
DiseaseAbnormal coordination

CACNA1A SCN8A

8.50e-0416802C0520966
DiseaseAtaxia, Truncal

CACNA1A SCN8A

8.50e-0416802C0427190
DiseaseParoxysmal Nerve Pain

SCN9A SCN10A

8.50e-0416802C0751373
DiseaseNerve Pain

SCN9A SCN10A

8.50e-0416802C0751372
DiseaseNeuralgia, Ilioinguinal

SCN9A SCN10A

8.50e-0416802C0751371
DiseaseNeuralgia, Vidian

SCN9A SCN10A

8.50e-0416802C0042656
DiseaseHuntington Disease

SLC29A1 HTT

9.61e-0417802C0020179
DiseaseFebrile seizure (within the age range of 3 months to 6 years)

SCN1A SCN2A

1.08e-0318802HP_0002373
Diseaseage at menarche

CMIP SCN2A MC3R DNM1 ECPAS ADCY3 EVI5L

1.16e-03594807EFO_0004703
DiseaseBrugada syndrome

SCN5A SCN10A

1.20e-0319802MONDO_0015263
DiseaseIntellectual Disability

SCN1A SCN3A SCN8A ACTL6B TRRAP HTT

1.37e-03447806C3714756
DiseaseEtat Marbre

SCN1A HTT

1.77e-0323802C0266487
Diseasedepressive symptom measurement, response to antidepressant

PIEZO1 WDFY4 ADCY3

1.78e-0388803EFO_0007006, GO_0036276
DiseaseBrugada Syndrome (disorder)

SCN5A SCN10A

1.93e-0324802C1142166
DiseaseWest Syndrome

SCN2A TSC2

1.93e-0324802C0037769
Diseasehealth study participation

CTNNA3 IFI30 CALN1 TANGO6

1.98e-03195804EFO_0010130
DiseaseAtaxia

CACNA1A SCN8A

2.09e-0325802C0004134
Diseaseergothioneine measurement

CACNA1A DNAH5

2.26e-0326802EFO_0021163

Protein segments in the cluster

PeptideGeneStartEntry
LCSFLMLNLFVAVIM

CACNA1A

1796

O00555
CAFNTLMELEVELMK

FAM209A

111

Q5JX71
LLMQMPEEEAFCVFV

EVI5L

206

Q96CN4
SLLCQNFSMVDVVML

BAG6

756

P46379
FLMNLSMFCTVLVQL

ADGRG4

2906

Q8IZF6
MQCRELFQEMAIDII

ACTL6B

201

O94805
NIAMFIVVMVQICGR

ADGRG6

1036

Q86SQ4
QTMVEILCLMLEYNI

CMIP

581

Q8IY22
EDLFMCMDIQLVEAL

DNAJA1

256

P31689
ICAFAMAFIISVMLI

CALN1

236

Q9BXU9
VNLVVMLAELFMCFE

CAMSAP3

301

Q9P1Y5
MLAMAAFCFIAALVI

OCLN

141

Q16625
VCLVQMFFVHALTAM

OR52W1

101

Q6IF63
MILEEFGRCLMSVIN

LIN54

721

Q6MZP7
ISFQALCMLLDFVSM

GPR158

421

Q5T848
IRDMLMQFVTKENCL

DNM1

156

Q05193
MADNACVLFAVSVLM

LAPTM4A

76

Q15012
IREMIMQFITRENCL

DNM3

156

Q9UQ16
METINMCLQYLDVSV

ECPAS

1341

Q5VYK3
IVMELMDANLCQVIQ

MAPK8

106

P45983
LTCIMYMIFQERDLL

PDE4A

391

P27815
NNMAMLICLIIIAVL

EVI2A

131

P22794
NELMLMAVLNCLFDS

COPZ1

86

P61923
MAVLNCLFDSLSQML

COPZ1

91

P61923
ATLVLAFLMICENMT

DUSP13

146

Q9UII6
AFLMICENMTLVEAI

DUSP13

151

Q9UII6
MLFAVMAFDLSVAIC

OR12D2

111

P58182
GCMEIFVLILMAVDR

OR4C11

106

Q6IEV9
MLLAVMAFDRFVAIC

OR12D1

111

P0DN82
MIDVMCLLQHVSAFQ

CTNNA3

141

Q9UI47
MMATVCVQQLLKTLF

HTT

1306

P42858
FNLMLMECSICNEII

KDM2B

681

Q8NHM5
ELDMELAFLTIVCME

IFI30

136

P13284
SFLLTFCALMIVEEM

FITM2

156

Q8N6M3
CARAEELFNMLQEIM

FRS2

91

Q8WU20
NIDFMVACMQFINIV

FMNL3

316

Q8IVF7
CVLGVMVLILMVFIA

CDON

971

Q4KMG0
GNMERIVICLMVIFL

IL21

6

Q9HBE4
LLISMAVCIIAMIIF

BMPR1A

156

P36894
LVMANVVDMLSCLQY

ADCY3

716

O60266
FQKMCDLLFVMFAVV

CERS6

256

Q6ZMG9
MDNIFDSMICISLVA

MC3R

116

P41968
MFLLLNCIVAVSQNM

DHFR2

1

Q86XF0
LFQEEGMLSMVLNCI

RYR1

476

P21817
TEAMMFIEEVCLSLL

FOCAD

241

Q5VW36
ILFRETECMAQMGLE

DNAH5

716

Q8TE73
CFVAITFMAAVMLVA

LRRC4B

581

Q9NT99
AILVARCEVMAAMFN

RHOBTB3

436

O94955
LLALVMFSMGCNVEI

SLC10A2

41

Q12908
VMMFCEVLKQQSCLL

NLRP3

986

Q96P20
EVAGQAMCLTVFLMV

SCN4A

771

P35499
FLSSFMLVMICVLIN

PKDREJ

2151

Q9NTG1
MLVMICVLINLFQAV

PKDREJ

2156

Q9NTG1
DAVLAFMARCLQVVM

FBXL18

631

Q96ME1
LTITMCIVLNTLFMA

SCN5A

721

Q14524
TICIVLNTLFMAMEH

SCN9A

751

Q15858
AFDISIMVLICLNMV

SCN9A

1516

Q15858
ITICIVLNTLFMAME

SCN3A

766

Q9NY46
QVFDISIMILICLNM

SCN3A

1526

Q9NY46
VMNMAAFLALVVAVL

TMEM150C

71

B9EJG8
LSAIFNNVMTLCAML

SLC29A1

76

Q99808
QVFDISIMILICLNM

SCN1A

1541

P35498
CFLLADMIMQSTDAI

CLDND2

146

Q8NHS1
NSLSVILMDLEYMIC

XPR1

401

Q9UBH6
LALKENVFMMVVCIE

RNF213

2746

Q63HN8
LIGVCQAEALMLVME

ZAP70

401

P43403
ITLCIVVNTIFMAME

SCN10A

671

Q9Y5Y9
QAFDITIMVLICLNM

SCN10A

1476

Q9Y5Y9
IVMFLVVMLCNQNYI

UBE4B

911

O95155
TICIVLNTLFMAMEH

SCN2A

766

Q99250
QVFDISIMILICLNM

SCN2A

1531

Q99250
VQKMFVQMLLNICSD

WDFY4

191

Q6ZS81
LMAVLCERMSEQIFT

TANGO6

646

Q9C0B7
MMLIFLGLDSQFVCV

SLC6A11

401

P48066
QQAFDIVIMMLICLN

SCN8A

1521

Q9UQD0
QMDQLVLVFMGCLLK

UBQLNL

66

Q8IYU4
TAFLVQLTELIHCMM

USP38

371

Q8NB14
NVMLMFTECVLDLTA

ULK2

831

Q8IYT8
TVKLQFDMMRACNLV

TMEM204

91

Q9BSN7
ICFQAIAMMIDTDVQ

SCN7A

1261

Q01118
MLSLLACVFVEQMQT

PIEZO1

1231

Q92508
MLITLACAAMTVIFF

WLS

436

Q5T9L3
CQEATLMVMVSKDLF

ZP3

46

P21754
VIKCFLVAMMSLEDN

TRRAP

966

Q9Y4A5
AFLLACVATMIFMIT

UGT2B17

496

O75795
LDEYIARMVQMICLL

TSC2

191

P49815
ICTAQALLANMAAMF

GLDC

381

P23378
MDVLPMCSIFQELQI

KLF6

1

Q99612
LLIVMSAISLQMFCF

NALCN

516

Q8IZF0