Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontransporter activity

ATP13A4 ATP8A2 HCN1 CFTR CYB561D2 SLC22A15 SLC46A1 SPNS3 SLC44A4 CHRNE SLC5A2 SLC5A3 ATP8A1 SLC17A1 SV2B SLC15A4 SLC22A2 SCN7A SLC35F6 KCNQ3 SV2C SLC5A8 M6PR SLC4A5 SLC6A14

3.67e-08128911225GO:0005215
GeneOntologyMolecularFunctiontransmembrane transporter activity

ATP13A4 HCN1 CFTR CYB561D2 SLC22A15 SLC46A1 SPNS3 SLC44A4 CHRNE SLC5A2 SLC5A3 ATP8A1 SLC17A1 SV2B SLC15A4 SLC22A2 SCN7A SLC35F6 KCNQ3 SV2C SLC5A8 SLC4A5 SLC6A14

1.31e-07118011223GO:0022857
GeneOntologyMolecularFunctionsolute:monoatomic cation symporter activity

SLC46A1 SLC5A2 SLC5A3 SLC17A1 SLC15A4 SLC5A8 SLC4A5 SLC6A14

3.56e-071191128GO:0015294
GeneOntologyMolecularFunctionactive transmembrane transporter activity

ATP13A4 CFTR CYB561D2 SLC46A1 SLC44A4 SLC5A2 SLC5A3 ATP8A1 SLC17A1 SLC15A4 SLC22A2 SLC5A8 SLC4A5 SLC6A14

4.62e-0747711214GO:0022804
GeneOntologyMolecularFunctionquaternary ammonium group transmembrane transporter activity

SLC22A15 SLC44A4 SLC22A2 SLC6A14

1.22e-06151124GO:0015651
GeneOntologyMolecularFunctionsymporter activity

SLC46A1 SLC5A2 SLC5A3 SLC17A1 SLC15A4 SLC5A8 SLC4A5 SLC6A14

2.07e-061501128GO:0015293
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

HCN1 SLC5A2 SLC5A3 SLC17A1 SCN7A SLC5A8 SLC4A5 SLC6A14

5.48e-061711128GO:0015081
GeneOntologyMolecularFunctionsolute:sodium symporter activity

SLC5A2 SLC5A3 SLC17A1 SLC5A8 SLC4A5 SLC6A14

6.27e-06811126GO:0015370
GeneOntologyMolecularFunctionactive monoatomic ion transmembrane transporter activity

ATP13A4 SLC46A1 SLC5A2 SLC5A3 ATP8A1 SLC17A1 SLC15A4 SLC5A8 SLC4A5 SLC6A14

7.61e-0630111210GO:0022853
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

ATP13A4 HCN1 SLC46A1 CHRNE SLC5A2 SLC5A3 ATP8A1 SLC17A1 SLC15A4 SCN7A KCNQ3 SLC5A8 SLC4A5 SLC6A14

2.10e-0566411214GO:0008324
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

ATP13A4 HCN1 CFTR SLC46A1 CHRNE SLC5A2 SLC5A3 ATP8A1 SLC17A1 SLC15A4 SCN7A KCNQ3 SLC5A8 SLC4A5 SLC6A14

3.67e-0579311215GO:0015075
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLC46A1 SLC44A4 SLC5A2 SLC5A3 SLC17A1 SLC15A4 SLC5A8 SLC4A5 SLC6A14

4.43e-052961129GO:0015291
GeneOntologyMolecularFunctionazole transmembrane transporter activity

SLC44A4 SLC15A4 SLC22A2

5.98e-05141123GO:1901474
GeneOntologyMolecularFunctionorganic cation transmembrane transporter activity

SLC22A15 SLC44A4 SLC15A4 SLC22A2 SLC6A14

1.04e-04831125GO:0015101
GeneOntologyMolecularFunctioncalcium-dependent cysteine-type endopeptidase activity

CAPN14 CAPN3 CAPN15

1.10e-04171123GO:0004198
GeneOntologyMolecularFunctionG protein-coupled receptor activity

OR2T33 MAS1 RXFP3 CHRM3 BDKRB1 ADGRG6 OR51E1 GPR61 GPR62 OR6C4 OR52E4 OR52E5 ADGRF5 ADGRE1 GABBR1

1.24e-0488411215GO:0004930
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

OR2T33 MAS1 RXFP3 CHRM3 BDKRB1 CHRNE ADGRG6 OR51E1 GPR61 GPR62 OR6C4 SCN7A OR52E4 OR52E5 ADGRF5 LTK ADGRE1 M6PR GABBR1

1.79e-04135311219GO:0004888
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

ATP13A4 HCN1 SLC46A1 SLC5A2 SLC5A3 SLC17A1 SLC15A4 SCN7A KCNQ3 SLC5A8 SLC4A5 SLC6A14

2.09e-0462711212GO:0022890
GeneOntologyMolecularFunctionorganic anion transmembrane transporter activity

CFTR SLC46A1 SLC44A4 SLC15A4 SLC22A2 SLC5A8 SLC4A5 SLC6A14

2.48e-042931128GO:0008514
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

ATP13A4 HCN1 SLC5A2 SLC5A3 SLC17A1 SCN7A KCNQ3 SLC5A8 SLC4A5 SLC6A14

2.90e-0446511210GO:0046873
GeneOntologyMolecularFunctionphosphatidylserine flippase activity

ATP8A2 ATP8A1

3.08e-0451122GO:0140346
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

ATP13A4 HCN1 CFTR SLC46A1 SLC5A2 SLC5A3 SLC17A1 SLC15A4 SCN7A KCNQ3 SLC5A8 SLC4A5 SLC6A14

3.27e-0475811213GO:0015318
GeneOntologyMolecularFunctionaminophospholipid flippase activity

ATP8A2 ATP8A1

6.43e-0471122GO:0015247
GeneOntologyMolecularFunctionthiamine transmembrane transporter activity

SLC44A4 SLC22A2

6.43e-0471122GO:0015234
GeneOntologyMolecularFunctionD-glucose:sodium symporter activity

SLC5A2 SLC5A3

6.43e-0471122GO:0005412
GeneOntologyMolecularFunctionmodified amino acid transmembrane transporter activity

SLC22A15 SLC46A1 SLC6A14

8.29e-04331123GO:0072349
GeneOntologyMolecularFunctioncholine transmembrane transporter activity

SLC44A4 SLC22A2

8.54e-0481122GO:0015220
GeneOntologyMolecularFunctionvitamin transmembrane transporter activity

SLC46A1 SLC44A4 SLC22A2

1.07e-03361123GO:0090482
GeneOntologyMolecularFunctionamine transmembrane transporter activity

SLC22A2 SLC6A14

1.09e-0391122GO:0005275
GeneOntologyMolecularFunctionphosphatidylserine floppase activity

ATP8A2 ATP8A1

1.09e-0391122GO:0090556
GeneOntologyMolecularFunctioncysteine-type endopeptidase activity

CAPN14 GPAA1 CAPN3 CAPN15

1.40e-03861124GO:0004197
GeneOntologyMolecularFunctionpolyamine transmembrane transporter activity

ATP13A4 SLC22A2

1.66e-03111122GO:0015203
GeneOntologyMolecularFunctionarrestin family protein binding

GPR61 GPR62

1.98e-03121122GO:1990763
GeneOntologyMolecularFunctionG protein-coupled neurotransmitter receptor activity

CHRM3 GABBR1

2.34e-03131122GO:0099528
GeneOntologyMolecularFunctionaromatic amino acid transmembrane transporter activity

SLC15A4 SLC6A14

2.34e-03131122GO:0015173
GeneOntologyMolecularFunctionglycerophospholipid flippase activity

ATP8A2 ATP8A1

2.72e-03141122GO:0140333
GeneOntologyMolecularFunctionbeta-1,3-galactosyltransferase activity

C1GALT1 B3GNT6

3.12e-03151122GO:0048531
GeneOntologyMolecularFunctionfloppase activity

ATP8A2 ATP8A1

3.55e-03161122GO:0140328
GeneOntologyMolecularFunctioncarbohydrate:monoatomic cation symporter activity

SLC5A2 SLC5A3

4.01e-03171122GO:0005402
GeneOntologyMolecularFunctionflippase activity

ATP8A2 ATP8A1

4.01e-03171122GO:0140327
GeneOntologyMolecularFunctioncarbohydrate derivative transmembrane transporter activity

SLC5A2 SLC15A4 SLC22A2

4.44e-03591123GO:1901505
GeneOntologyMolecularFunctionbasic amino acid transmembrane transporter activity

SLC15A4 SLC22A2

5.55e-03201122GO:0015174
GeneOntologyBiologicalProcessquaternary ammonium group transport

SLC22A15 SLC44A4 SLC22A2 SLC6A14

2.89e-06191114GO:0015697
GeneOntologyBiologicalProcesssodium ion transmembrane transport

HCN1 CFTR SLC5A2 SLC5A3 SLC17A1 SCN7A SLC4A5 SLC6A14

1.70e-052081118GO:0035725
GeneOntologyBiologicalProcesssodium ion transport

HCN1 CFTR SLC5A2 SLC5A3 SLC17A1 SCN7A SLC5A8 SLC4A5 SLC6A14

1.80e-052751119GO:0006814
GeneOntologyBiologicalProcessligand-independent adenylate cyclase-activating G protein-coupled receptor signaling pathway

GPR61 GPR62

2.87e-0521112GO:0038035
GeneOntologyBiologicalProcessmonoatomic cation transmembrane transport

ATP13A4 HCN1 CFTR CAPN3 SLC46A1 BDKRB1 CHRNE SLC5A2 SLC5A3 ATP8A1 SLC17A1 SLC15A4 SCN7A KCNQ3 SLC4A5 SLC6A14

4.38e-0594211116GO:0098655
GeneOntologyBiologicalProcessmonoatomic cation transport

ATP13A4 HCN1 CFTR CAPN3 SLC46A1 BDKRB1 CHRNE SLC5A2 SLC5A3 ATP8A1 SLC17A1 SLC15A4 SLC22A2 SCN7A KCNQ3 SLC5A8 SLC4A5 SLC6A14

4.41e-05115711118GO:0006812
GeneOntologyBiologicalProcessazole transmembrane transport

SLC44A4 SLC15A4 SLC22A2

6.58e-05151113GO:0045117
GeneOntologyBiologicalProcessorganic anion transport

CFTR SLC46A1 SLC44A4 SLC17A1 SLC15A4 SLC22A2 SLC5A8 PRAF2 SLC4A5 GABBR1 SLC6A14

1.05e-0451511111GO:0015711
GeneOntologyBiologicalProcessmonoatomic ion transport

ATP13A4 HCN1 CFTR CAPN3 SLC22A15 SLC46A1 BDKRB1 CHRNE SLC5A2 SLC5A3 ATP8A1 SLC17A1 SLC15A4 SLC22A2 SCN7A KCNQ3 SLC5A8 SLC4A5 SLC6A14

1.27e-04137411119GO:0006811
GeneOntologyBiologicalProcessadenylate cyclase-modulating G protein-coupled receptor signaling pathway

CHRM3 ADCY8 ADGRG6 GPR61 GPR62 ADGRF5 ADGRE1 GABBR1

1.59e-042861118GO:0007188
GeneOntologyBiologicalProcessmembrane hyperpolarization

HCN1 CFTR KCNQ3

1.88e-04211113GO:0060081
GeneOntologyBiologicalProcessvitamin transmembrane transport

SLC46A1 SLC44A4 SLC22A2

2.48e-04231113GO:0035461
GeneOntologyCellularComponentapical plasma membrane

TNIK CFTR SLC46A1 SLC44A4 ADCY8 SLC5A2 SLC5A3 SLC17A1 SLC22A2 CD81 SLC5A8 SLC4A5 SLC6A14

2.12e-0648711213GO:0016324
GeneOntologyCellularComponentapical part of cell

TNIK CFTR SLC46A1 SLC44A4 ADCY8 SLC5A2 SLC5A3 SLC17A1 SLC22A2 CD81 ADGRF5 SLC5A8 SLC4A5 SLC6A14

3.43e-0659211214GO:0045177
GeneOntologyCellularComponentcytoplasmic vesicle membrane

ATP13A4 ATP8A2 CFTR CYB561D2 SLC46A1 ADCY8 CD163 ZFYVE28 ATP8A1 GPR61 SYT8 SV2B GPR62 SLC15A4 SLC22A2 SYPL2 AP1G2 SV2C LEPROT PRAF2 M6PR

5.31e-06130711221GO:0030659
GeneOntologyCellularComponentvesicle membrane

ATP13A4 ATP8A2 CFTR CYB561D2 SLC46A1 ADCY8 CD163 ZFYVE28 ATP8A1 GPR61 SYT8 SV2B GPR62 SLC15A4 SLC22A2 SYPL2 AP1G2 SV2C LEPROT PRAF2 M6PR

6.56e-06132511221GO:0012506
GeneOntologyCellularComponentbasolateral plasma membrane

HCN1 CFTR SLC46A1 CHRM3 ADCY8 SLC5A3 SLC22A2 CD81 SLC4A5

5.70e-053201129GO:0016323
GeneOntologyCellularComponentbasal plasma membrane

HCN1 CFTR SLC46A1 CHRM3 ADCY8 SLC5A3 SLC22A2 CD81 SLC4A5

1.23e-043541129GO:0009925
GeneOntologyCellularComponentbrush border

MYH10 MYH11 SLC46A1 SLC5A2 SLC5A8 SLC6A14

1.70e-041521126GO:0005903
GeneOntologyCellularComponentbasal part of cell

HCN1 CFTR SLC46A1 CHRM3 ADCY8 SLC5A3 SLC22A2 CD81 SLC4A5

2.01e-043781129GO:0045178
GeneOntologyCellularComponentpresynapse

TNIK OGT HCN1 CNTNAP1 CHRM3 ADCY8 ATP8A1 SYT8 SV2B SLC22A2 SYPL2 SV2C PRAF2 GABBR1

2.76e-0488611214GO:0098793
GeneOntologyCellularComponentendosome membrane

ATP13A4 ATP8A2 CFTR SLC46A1 ZFYVE28 GPR61 GPR62 SLC15A4 AP1G2 LEPROT PRAF2

3.91e-0460211211GO:0010008
GeneOntologyCellularComponentexocytic vesicle membrane

ATP8A1 SYT8 SV2B SLC22A2 SYPL2 SV2C

4.10e-041791126GO:0099501
GeneOntologyCellularComponentsynaptic vesicle membrane

ATP8A1 SYT8 SV2B SLC22A2 SYPL2 SV2C

4.10e-041791126GO:0030672
GeneOntologyCellularComponenttransport vesicle membrane

ATP8A1 SYT8 SV2B SLC22A2 SYPL2 AP1G2 SV2C

1.02e-032931127GO:0030658
GeneOntologyCellularComponentbrush border membrane

SLC46A1 SLC5A2 SLC5A8 SLC6A14

1.04e-03831124GO:0031526
GeneOntologyCellularComponentsynaptic vesicle

ATP8A1 SYT8 SV2B SLC22A2 SYPL2 SV2C GABBR1

1.17e-033001127GO:0008021
GeneOntologyCellularComponentcluster of actin-based cell projections

MYH10 MYH11 SLC46A1 SLC5A2 SLC5A8 SLC6A14

1.29e-032231126GO:0098862
GeneOntologyCellularComponentglutamatergic synapse

TNIK SEMA4B MYH10 OGT HCN1 CNTNAP1 CHRM3 ADCY8 ATP8A1 SV2B PRAF2 GABBR1

1.44e-0381711212GO:0098978
GeneOntologyCellularComponentexocytic vesicle

ATP8A1 SYT8 SV2B SLC22A2 SYPL2 SV2C GABBR1

1.70e-033201127GO:0070382
GeneOntologyCellularComponenttransport vesicle

ATP8A1 SYT8 SV2B SLC22A2 SYPL2 AP1G2 SV2C M6PR GABBR1

1.92e-035191129GO:0030133
GeneOntologyCellularComponentphospholipid-translocating ATPase complex

ATP8A2 ATP8A1

2.48e-03141122GO:1990531
DomainMFS_dom

SLC22A15 SLC46A1 SPNS3 SLC17A1 SV2B SLC15A4 SLC22A2 SV2C

1.26e-061341108IPR020846
DomainMFS

SLC22A15 SLC46A1 SPNS3 SLC17A1 SV2B SLC22A2 SV2C

3.47e-061081107PS50850
DomainNA_SOLUT_SYMP_1

SLC5A2 SLC5A3 SLC5A8

3.17e-05111103PS00456
DomainFAM212

INKA2 INKA1

3.44e-0521102IPR029267
DomainFAM212

INKA2 INKA1

3.44e-0521102PF15342
DomainSugar_transporter_CS

SLC46A1 SV2B SLC22A2 SV2C

3.61e-05321104IPR005829
DomainNA_SOLUT_SYMP_2

SLC5A2 SLC5A3 SLC5A8

4.21e-05121103PS00457
DomainSSF

SLC5A2 SLC5A3 SLC5A8

4.21e-05121103PF00474
DomainNa/solute_symporter

SLC5A2 SLC5A3 SLC5A8

4.21e-05121103IPR001734
DomainNA_SOLUT_SYMP_3

SLC5A2 SLC5A3 SLC5A8

4.21e-05121103PS50283
DomainMFS_sugar_transport-like

SLC22A15 SV2B SLC22A2 SV2C

5.80e-05361104IPR005828
DomainSugar_tr

SLC22A15 SV2B SLC22A2 SV2C

5.80e-05361104PF00083
DomainCalpain_cysteine_protease

CAPN14 CAPN3 CAPN15

6.90e-05141103IPR022684
DomainCysPc

CAPN14 CAPN3 CAPN15

8.59e-05151103SM00230
DomainPeptidase_C2_calpain_cat

CAPN14 CAPN3 CAPN15

8.59e-05151103IPR001300
DomainPeptidase_C2

CAPN14 CAPN3 CAPN15

8.59e-05151103PF00648
DomainCALPAIN_CAT

CAPN14 CAPN3 CAPN15

8.59e-05151103PS50203
DomainMFS_1

SLC46A1 SPNS3 SLC17A1 SV2B SV2C

9.12e-05771105PF07690
DomainMFS

SLC46A1 SPNS3 SLC17A1 SV2B SV2C

9.12e-05771105IPR011701
DomainSV2

SV2B SV2C

1.03e-0431102IPR022308
DomainPentapeptide_4

SV2B SV2C

1.03e-0431102PF13599
Domain5peptide_repeat

SV2B SV2C

2.05e-0441102IPR001646
DomainMyosin_S1_N

MYH10 MYH11

3.40e-0451102IPR008989
DomainTHIOL_PROTEASE_CYS

CAPN14 CAPN3 CAPN15

4.68e-04261103PS00139
DomainTHIOL_PROTEASE_ASN

CAPN14 CAPN3 CAPN15

5.25e-04271103PS00640
DomainTHIOL_PROTEASE_HIS

CAPN14 CAPN3 CAPN15

5.25e-04271103PS00639
DomainPept_cys_AS

CAPN14 CAPN3 CAPN15

5.85e-04281103IPR000169
DomainRNase_Zc3h12a

KHNYN NYNRIN

7.08e-0471102PF11977
DomainRNase_Zc3h12_NYN

KHNYN NYNRIN

7.08e-0471102IPR021869
DomainPSI

SEMA4B MEGF8 SEMA4A

8.71e-04321103PF01437
Domain-

ATP13A4 ATP8A2 ATP8A1

8.71e-043211033.40.1110.10
DomainPlexin_repeat

SEMA4B MEGF8 SEMA4A

8.71e-04321103IPR002165
Domain-

ATP13A4 ATP8A2 ATP8A1

8.71e-043211032.70.150.10
DomainNa/solute_symporter_CS

SLC5A2 SLC5A3

9.40e-0481102IPR018212
DomainGPS

ADGRG6 ADGRF5 ADGRE1

1.04e-03341103SM00303
DomainGPCR_2_secretin-like_CS

ADGRG6 ADGRF5 ADGRE1

1.04e-03341103IPR017983
DomainGPS

ADGRG6 ADGRF5 ADGRE1

1.13e-03351103PF01825
DomainATPase_P-typ_cyto_domN

ATP13A4 ATP8A2 ATP8A1

1.13e-03351103IPR023299
DomainP_typ_ATPase

ATP13A4 ATP8A2 ATP8A1

1.23e-03361103IPR001757
DomainATPase_P-typ_P_site

ATP13A4 ATP8A2 ATP8A1

1.23e-03361103IPR018303
DomainGPS

ADGRG6 ADGRF5 ADGRE1

1.23e-03361103PS50221
DomainATPASE_E1_E2

ATP13A4 ATP8A2 ATP8A1

1.23e-03361103PS00154
DomainGPS

ADGRG6 ADGRF5 ADGRE1

1.33e-03371103IPR000203
DomainATPase_P-typ_transduc_dom_A

ATP13A4 ATP8A2 ATP8A1

1.33e-03371103IPR008250
DomainE1-E2_ATPase

ATP13A4 ATP8A2 ATP8A1

1.33e-03371103PF00122
Domain7tm_1

OR2T33 MAS1 RXFP3 CHRM3 BDKRB1 OR51E1 GPR61 GPR62 OR6C4 OR52E4 OR52E5

2.16e-0367711011PF00001
DomainCalpain_III

CAPN14 CAPN3

2.18e-03121102IPR022683
Domaincalpain_III

CAPN14 CAPN3

2.18e-03121102SM00720
DomainC2_III

CAPN14 CAPN3

2.18e-03121102IPR033883
DomainPSI

SEMA4B MEGF8 SEMA4A

2.21e-03441103IPR016201
DomainG_PROTEIN_RECEP_F1_1

OR2T33 MAS1 RXFP3 CHRM3 BDKRB1 OR51E1 GPR61 GPR62 OR6C4 OR52E4 OR52E5

2.36e-0368511011PS00237
Domain-

NBEAL1 CNTNAP1 SHBG ADGRG6

2.40e-039511042.60.120.200
DomainPSI

SEMA4B MEGF8 SEMA4A

2.51e-03461103SM00423
DomainG_PROTEIN_RECEP_F1_2

OR2T33 MAS1 RXFP3 CHRM3 BDKRB1 OR51E1 GPR61 GPR62 OR6C4 OR52E4 OR52E5

2.53e-0369111011PS50262
DomainGPCR_Rhodpsn

OR2T33 MAS1 RXFP3 CHRM3 BDKRB1 OR51E1 GPR61 GPR62 OR6C4 OR52E4 OR52E5

2.56e-0369211011IPR000276
DomainCalpain_domain_III

CAPN14 CAPN3

2.57e-03131102IPR022682
DomainCalpain_III

CAPN14 CAPN3

2.57e-03131102PF01067
DomainP_typ_ATPase_c

ATP8A2 ATP8A1

2.99e-03141102IPR032630
DomainP-type_ATPase_N

ATP8A2 ATP8A1

2.99e-03141102IPR032631
DomainP-type_ATPase_IV

ATP8A2 ATP8A1

2.99e-03141102IPR006539
DomainPhoLip_ATPase_C

ATP8A2 ATP8A1

2.99e-03141102PF16212
DomainPhoLip_ATPase_N

ATP8A2 ATP8A1

2.99e-03141102PF16209
DomainCNH

TNIK MINK1

2.99e-03141102SM00036
DomainG_PROTEIN_RECEP_F2_2

ADGRG6 ADGRF5 ADGRE1

3.19e-03501103PS00650
Domain7tm_2

ADGRG6 ADGRF5 ADGRE1

3.19e-03501103PF00002
DomainMyosin_N

MYH10 MYH11

3.43e-03151102PF02736
DomainCNH

TNIK MINK1

3.43e-03151102PF00780
DomainMyosin_N

MYH10 MYH11

3.43e-03151102IPR004009
DomainCNH

TNIK MINK1

3.43e-03151102PS50219
DomainCNH_dom

TNIK MINK1

3.43e-03151102IPR001180
Domain-

SEMA4B NBEAL1 WDR27 EDC4 WDR37 TECPR2 SEMA4A

3.57e-0333311072.130.10.10
DomainWD40/YVTN_repeat-like_dom

SEMA4B NBEAL1 WDR27 EDC4 WDR37 TECPR2 SEMA4A

3.69e-033351107IPR015943
DomainMyosin_tail_1

MYH10 MYH11

4.95e-03181102PF01576
DomainMyosin_tail

MYH10 MYH11

4.95e-03181102IPR002928
DomainGPCR_2_secretin-like

ADGRG6 ADGRF5 ADGRE1

5.33e-03601103IPR000832
DomainGPCR_2-like

ADGRG6 ADGRF5 ADGRE1

5.33e-03601103IPR017981
DomainMyosin-like_IQ_dom

MYH10 MYH11

5.51e-03191102IPR027401
Domain-

MYH10 MYH11

5.51e-031911024.10.270.10
DomainG_PROTEIN_RECEP_F2_4

ADGRG6 ADGRF5 ADGRE1

5.58e-03611103PS50261
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC22A15 SLC44A4 SLC5A2 SLC5A3 SLC17A1 SLC15A4 SLC22A2 SLC5A8 SLC4A5 SLC6A14

2.00e-062388710MM15076
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

ATP13A4 ATP8A2 CFTR SLC22A15 SLC46A1 SLC44A4 ADCY8 SLC5A2 SLC5A3 ATP8A1 MBTPS2 SLC17A1 SLC15A4 SLC22A2 SLC5A8 SLC4A5 SLC6A14

2.10e-067368717M27287
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC22A15 SLC44A4 SLC5A2 SLC5A3 SLC17A1 SLC15A4 SLC22A2 SLC5A8 SLC4A5 SLC6A14

3.00e-062498710M5988
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

ATP13A4 ATP8A2 CFTR SLC22A15 SLC46A1 SLC44A4 SLC5A2 SLC5A3 ATP8A1 SLC17A1 SLC15A4 SLC22A2 SLC5A8 SLC4A5 SLC6A14

1.61e-056818715MM14985
PathwayREACTOME_TRANSPORT_OF_BILE_SALTS_AND_ORGANIC_ACIDS_METAL_IONS_AND_AMINE_COMPOUNDS

SLC22A15 SLC44A4 SLC5A3 SLC22A2 SLC6A14

1.04e-0476875MM15072
PathwayREACTOME_TRANSPORT_OF_BILE_SALTS_AND_ORGANIC_ACIDS_METAL_IONS_AND_AMINE_COMPOUNDS

SLC22A15 SLC44A4 SLC5A3 SLC22A2 SLC6A14

1.68e-0484875M27334
PathwayWP_GPCRS_OTHER

RXFP3 CHRM3 GPR61 GPR62 ADGRF5

2.70e-0493875M39629
PathwayREACTOME_TOXICITY_OF_BOTULINUM_TOXIN_TYPE_D_BOTD

SV2B SV2C

3.72e-045872M27427
PathwayREACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES

SLC17A1 SLC15A4 SLC5A8 SLC4A5 SLC6A14

5.40e-04108875M823
PathwayREACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES

SLC17A1 SLC15A4 SLC5A8 SLC4A5 SLC6A14

5.63e-04109875MM15074
Pubmed

Systematic protein-protein interaction mapping for clinically relevant human GPCRs.

GPAA1 CNTNAP1 RHBDD2 RXFP3 CHRM3 BDKRB1 TSPAN3 METRN TECPR2 SLC15A4 CD81 LEPROT MTCH1 GABBR1

6.54e-086971131428298427
Pubmed

Pulmonary neuroendocrine cells, airway innervation, and smooth muscle are altered in Cftr null mice.

CFTR SV2B SV2C

6.63e-076113316614351
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

SEMA4B ANKRD37 RPS6KA2 KHNYN CYB561D2 CUL9 EDC4 MEGF8 PAXIP1 AP1G2 LTK PREX1 TNPO3 TRAPPC9 CD276

3.05e-0611051131535748872
Pubmed

Genome-wide data reveal novel genes for methotrexate response in a large cohort of juvenile idiopathic arthritis cases.

CFTR ELFN2 ADCY8 ANGPTL5

7.96e-0639113424709693
Pubmed

Constriction velocities of renal afferent and efferent arterioles of mice are not related to SMB expression.

MYH10 MYH11

1.05e-052113216316347
Pubmed

Overlapping of MINK and CHRNE gene loci in the course of mammalian evolution.

MINK1 CHRNE

1.05e-052113212087176
Pubmed

Heme carrier protein (HCP-1) spatially interacts with the CD163 hemoglobin uptake pathway and is a target of inflammatory macrophage activation.

SLC46A1 CD163

1.05e-052113217947394
Pubmed

SLC5A8 triggers tumor cell apoptosis through pyruvate-dependent inhibition of histone deacetylases.

SLC5A3 SLC5A8

1.05e-052113217178845
Pubmed

Loss of intestinal O-glycans promotes spontaneous duodenal tumors.

C1GALT1 B3GNT6

1.05e-052113227229122
Pubmed

SLC6A14, an amino acid transporter, modifies the primary CF defect in fluid secretion.

CFTR SLC6A14

1.05e-052113230004386
Pubmed

Detailed O-glycomics of the Muc2 mucin from colon of wild-type, core 1- and core 3-transferase-deficient mice highlights differences compared with human MUC2.

C1GALT1 B3GNT6

1.05e-052113222581805
Pubmed

Myosin heavy chain gene expression in normal and hyperplastic human prostate tissue.

MYH10 MYH11

1.05e-052113210906735
Pubmed

Human smooth muscle myosin heavy chain isoforms as molecular markers for vascular development and atherosclerosis.

MYH10 MYH11

1.05e-05211327916668
Pubmed

Role of tyrosine phosphorylation in the muscarinic activation of the cystic fibrosis transmembrane conductance regulator (CFTR).

CFTR CHRM3

1.05e-052113223760269
Pubmed

CGIN1: a retroviral contribution to mammalian genomes.

KHNYN NYNRIN

1.05e-052113219561090
Pubmed

Long-term potentiation modulates synaptic phosphorylation networks and reshapes the structure of the postsynaptic interactome.

TNIK SLK HCN1 RPS6KA2 MINK1 CNTNAP1 PRAF2

1.89e-05251113727507650
Pubmed

Kv7/KCNQ potassium channels in cortical hyperexcitability and juvenile seizure-related death in Ank2-mutant mice.

CNTNAP1 SLC17A1 KCNQ3

2.63e-0518113337321992
Pubmed

Expression pattern of synaptic vesicle protein 2 (SV2) isoforms in patients with temporal lobe epilepsy and hippocampal sclerosis.

SV2B SV2C

3.13e-053113223617838
Pubmed

An in cellulo-derived structure of PAK4 in complex with its inhibitor Inka1.

INKA2 INKA1

3.13e-053113226607847
Pubmed

Noise-induced plasticity of KCNQ2/3 and HCN channels underlies vulnerability and resilience to tinnitus.

HCN1 KCNQ3

3.13e-053113226312501
Pubmed

Effects of h1-calponin ablation on the contractile properties of bladder versus vascular smooth muscle in mice lacking SM-B myosin.

MYH10 MYH11

3.13e-053113216973711
Pubmed

SMIT1 Modifies KCNQ Channel Function and Pharmacology by Physical Interaction with the Pore.

SLC5A3 KCNQ3

3.13e-053113228793216
Pubmed

No major role of common SV2A variation for predisposition or levetiracetam response in epilepsy.

SV2B SV2C

3.13e-053113218977120
Pubmed

MINK is a Rap2 effector for phosphorylation of the postsynaptic scaffold protein TANC1.

TNIK MINK1

3.13e-053113218930710
Pubmed

SV2 is the protein receptor for botulinum neurotoxin A.

SV2B SV2C

3.13e-053113216543415
Pubmed

Differential distribution and developmental expression of synaptic vesicle protein 2 isoforms in the mouse retina.

SV2B SV2C

3.13e-053113212687700
Pubmed

Expression of SV2 isoforms during rodent brain development.

SV2B SV2C

3.13e-053113223937191
Pubmed

SV2 modulates the size of the readily releasable pool of secretory vesicles.

SV2B SV2C

3.13e-053113211483953
Pubmed

Spindle cell neoplasms with novel LTK fusion - Expanding the spectrum of kinase fusion-positive soft tissue tumors.

MYH10 LTK

3.13e-053113238517106
Pubmed

Differentiation of two human neuroblastoma cell lines alters SV2 expression patterns.

SV2B SV2C

3.13e-053113233588752
Pubmed

Transport through recycling endosomes requires EHD1 recruitment by a phosphatidylserine translocase.

ATP8A2 ATP8A1

3.13e-053113225595798
Pubmed

An approach based on a genome-wide association study reveals candidate loci for narcolepsy.

MYH10 WDR37 ADCY8 ADGRG6 CCN4 ALOX15B

4.17e-05193113620677014
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

TNIK SLK MYH10 KHNYN CUL9 EPG5 MEGF8 SV2B

5.76e-05407113812693553
Pubmed

Identification of four novel human G protein-coupled receptors expressed in the brain.

GPR61 GPR62

6.25e-054113211165367
Pubmed

The Muc2 mucin coats murine Paneth cell granules and facilitates their content release and dispersion.

C1GALT1 B3GNT6

6.25e-054113229698056
Pubmed

Orphan GPR61, GPR62 and GPR135 receptors and the melatonin MT2 receptor reciprocally modulate their signaling functions.

GPR61 GPR62

6.25e-054113228827538
Pubmed

CPEB2-eEF2 interaction impedes HIF-1α RNA translation.

SEMA4B GABBR1 CAPN15

6.43e-0524113322157746
Pubmed

Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.

CHRM3 TSPAN3 STT3B ADGRG6 SLC35F6 ADGRF5 LEPROT CD276

8.45e-05430113816303743
Pubmed

Inka2, a novel Pak4 inhibitor, regulates actin dynamics in neuronal development.

INKA2 INKA1

1.04e-045113236301793
Pubmed

A semaphorin-plexin-Rasal1 signaling pathway inhibits gastrin expression and protects against peptic ulcers.

SEMA4B SEMA4A

1.04e-045113235857828
Pubmed

The NYN domains: novel predicted RNAses with a PIN domain-like fold.

KHNYN NYNRIN

1.04e-045113217114934
Pubmed

Telokin expression is restricted to smooth muscle tissues during mouse development.

MYH10 MYH11

1.04e-045113211121372
Pubmed

The human and mouse repertoire of the adhesion family of G-protein-coupled receptors.

ADGRG6 ADGRF5 ADGRE1

1.15e-0429113315203201
Pubmed

Large-scale proteomics and phosphoproteomics of urinary exosomes.

SLK CAPG MINK1 SLC44A4 TSPAN3 SLC5A2 MEGF8 SLC22A2 SLC35F6 CD81 ATIC SLC5A8

1.20e-0410161131219056867
Pubmed

Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.

HCN1 MINK1 CNTNAP1 ELFN2 ATP8A1 MTCH1 GABBR1

1.45e-04347113717114649
Pubmed

Murine semaphorin D/collapsin is a member of a diverse gene family and creates domains inhibitory for axonal extension.

SEMA4B SEMA4A

1.56e-04611327748561
Pubmed

SV2B regulates synaptotagmin 1 by direct interaction.

SV2B SV2C

1.56e-046113215466855
Pubmed

Targeted Disruption of Ig-Hepta/Gpr116 Causes Emphysema-like Symptoms That Are Associated with Alveolar Macrophage Activation.

ADGRF5 ADGRE1

1.56e-046113225778400
Pubmed

International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G protein-coupled receptors.

ADGRG6 ADGRF5 ADGRE1

1.70e-0433113325713288
Pubmed

Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.

SEMA4B SLK GPAA1 RHBDD2 SLC46A1 ADGRG6 INTS2 SLC15A4 SLC35F6 CD81 PRAF2 MTCH1

1.79e-0410611131233845483
Pubmed

Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.

SEMA4B SHBG CD163 ADGRG6 MEGF8 ADGRF5

2.01e-04257113616335952
Pubmed

Heteromeric interactions required for abundance and subcellular localization of human CDC50 proteins and class 1 P4-ATPases.

ATP8A2 ATP8A1

2.17e-047113220947505
Pubmed

Bidirectional action of the Igf2r imprint control element on upstream and downstream imprinted genes.

MAS1 SLC22A2

2.89e-048113211562346
Pubmed

Long-range DNase I hypersensitivity mapping reveals the imprinted Igf2r and Air promoters share cis-regulatory elements.

MAS1 SLC22A2

2.89e-048113216204191
Pubmed

Synaptobrevin is essential for secretion but not for the development of synaptic processes.

SV2B SV2C

2.89e-04811328738414
Pubmed

Distinct Roles of Smooth Muscle and Non-muscle Myosin Light Chain-Mediated Smooth Muscle Contraction.

MYH10 MYH11

2.89e-048113233424621
Pubmed

Viral Infection-Induced Differential Expression of LncRNAs Associated with Collagen in Mouse Placentas and Amniotic Sacs.

ANKRD37 ATP8A2 WDR37 TRAPPC9

3.26e-04100113426073538
Pubmed

Tissue-specific regulation of Igf2r/Airn imprinting during gastrulation.

MAS1 SLC22A2

3.71e-049113225918552
Pubmed

The sensory innervation of the mouse spinal cord may be patterned by differential expression of and differential responsiveness to semaphorins.

SEMA4B SEMA4A

3.71e-04911328812066
Pubmed

Semaphorin-Plexin Signaling Controls Mitotic Spindle Orientation during Epithelial Morphogenesis and Repair.

SEMA4B SEMA4A

3.71e-049113225892012
Pubmed

Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment.

CNTNAP1 SHBG CHRM3 BDKRB1 CHRNE GABBR1

4.57e-04300113619086053
Pubmed

Expression and localisation of dynamin and syntaxin during neural development and neuromuscular synapse formation.

SV2B SV2C

4.63e-0410113210398046
Pubmed

Orphan G-Protein Coupled Receptor GPRC5B Is Critical for Lymphatic Development.

GPR61 ADGRF5

4.63e-0410113235628521
Pubmed

Expression screening of a yeast artificial chromosome contig refines the location of the mouse H3a minor histocompatibility antigen gene.

CAPN3 LTK

4.63e-041011329670959
Pubmed

Generation of GABAergic and dopaminergic interneurons from endogenous embryonic olfactory bulb precursor cells.

SV2B SV2C

4.63e-0410113217038521
Pubmed

HDAC6 interacts with PTPN1 to enhance melanoma cells progression.

CNTNAP1 TGM3

4.63e-0410113229278704
Pubmed

The type 4 subfamily of P-type ATPases, putative aminophospholipid translocases with a role in human disease.

ATP8A2 ATP8A1

4.63e-0410113215919184
Pubmed

Functional analysis of Asb-1 using genetic modification in mice.

ASB10 ASB3

5.65e-0411113211509662
Pubmed

Restoration of synapse formation in Musk mutant mice expressing a Musk/Trk chimeric receptor.

SV2B SV2C

5.65e-0411113212403715
Pubmed

Multiple roles of integrin-α3 at the neuromuscular junction.

SV2B SV2C

6.76e-0412113228386022
Pubmed

Cleavage of human and mouse cytoskeletal and sarcomeric proteins by human immunodeficiency virus type 1 protease. Actin, desmin, myosin, and tropomyosin.

MYH10 MYH11

6.76e-041211328424456
Pubmed

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.

MYH10 MYH11 CAPG SHBG SLC44A4 ATP8A1 MEGF8 CD81 ATIC SLC5A8 ALOX15B

7.42e-0410701131123533145
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

SLK MYH10 MYH11 OGT MINK1 CNTNAP1 EDC4 WDR37 ELFN2 ATP8A1 SV2B KCNQ3 TRAPPC9

7.74e-0414311131337142655
Pubmed

An antagonistic interaction between PlexinB2 and Rnd3 controls RhoA activity and cortical neuron migration.

SEMA4B SEMA4A

7.97e-0413113224572910
Pubmed

Differential expression of putative transbilayer amphipath transporters.

ATP8A2 ATP8A1

7.97e-0413113211015572
Pubmed

Kirrel3 is required for the coalescence of vomeronasal sensory neuron axons into glomeruli and for male-male aggression.

SV2B SV2C

7.97e-0413113223637329
Pubmed

Cell Surface Proteomic Map of HIV Infection Reveals Antagonism of Amino Acid Metabolism by Vpu and Nef.

CHRM3 ELFN2 CD81 SEMA4A

9.27e-04132113426439863
Pubmed

Roles of neurotransmitter in synapse formation: development of neuromuscular junctions lacking choline acetyltransferase.

SV2B SV2C

9.28e-0414113212441053
Pubmed

Genetic analysis of the organic cation transporter genes Orct2/Slc22a2 and Orct3/Slc22a3 reduces the critical region for the t haplotype mutant t(w73) to 200 kb.

MAS1 SLC22A2

9.28e-0414113211641723
Pubmed

PDZK1: I. a major scaffolder in brush borders of proximal tubular cells.

SLK SLC17A1

9.28e-0414113214531806
Pubmed

Calcium channels link the muscle-derived synapse organizer laminin β2 to Bassoon and CAST/Erc2 to organize presynaptic active zones.

SV2B SV2C

9.28e-0414113221228161
Pubmed

Mapping of the genes for four members of the transmembrane 4 superfamily: mouse Cd9, Cd63, Cd81, and Cd82.

SCN7A CD81

9.28e-041411327590978
Pubmed

Network organization of the huntingtin proteomic interactome in mammalian brain.

TNIK MYH10 MYH11 HCN1 RPS6KA2 MINK1 CNTNAP1 ATP8A1

9.79e-04621113822794259
Pubmed

Rap2A links intestinal cell polarity to brush border formation.

TNIK MINK1

1.07e-0315113222797597
Pubmed

Semaphorin 4C and 4G are ligands of Plexin-B2 required in cerebellar development.

SEMA4B SEMA4A

1.07e-0315113221122816
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

MYH10 OGT RPS6KA2 MINK1 WDR27 WDR37 CHRM3 INKA2 ADGRG6 INTS2 TECPR2 SLC4A5 TRAPPC9

1.11e-0314891131328611215
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

SEMA4B MYH11 ELFN2 SV2C ADGRF5 PREX1 TRAPPC9

1.17e-03493113715368895
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

TNIK SLK MYH10 OGT HCN1 RPS6KA2 MINK1 CNTNAP1 EDC4 PRAF2

1.20e-039631131028671696
Pubmed

Balance between BDNF and Semaphorins gates the innervation of the mammary gland.

SEMA4B SEMA4A

1.22e-0316113230628891
Pubmed

Requirement for Slit-1 and Robo-2 in zonal segregation of olfactory sensory neuron axons in the main olfactory bulb.

SV2B SV2C

1.22e-0316113217715346
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

TNIK MYH10 HCN1 MINK1 CNTNAP1 EDC4 ELFN2 STT3B KCNQ3 MTCH1 GABBR1

1.23e-0311391131136417873
Pubmed

Interpreting cancer genomes using systematic host network perturbations by tumour virus proteins.

GPAA1 CNTNAP1 STT3B SLC5A3 SLC15A4 PRAF2 MTCH1

1.25e-03499113722810586
Pubmed

Hypermethylation of UCHL1 Promotes Metastasis of Nasopharyngeal Carcinoma by Suppressing Degradation of Cortactin (CTTN).

MYH10 MYH11 CD163

1.26e-0365113332120844
Pubmed

New loci associated with kidney function and chronic kidney disease.

WDR37 SLC22A2 SYPL2

1.32e-0366113320383146
Pubmed

Mapping of five subtype genes for muscarinic acetylcholine receptor to mouse chromosomes.

CHRM3 SCN7A

1.38e-0317113210549128
Pubmed

The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.

SEMA4B ATP13A4 SLC22A15 SLC44A4 SYPL2 SLC35F6 SEMA4A MTCH1 ANGPTL5 CD276

1.42e-039851131012975309
Pubmed

Serological detection of cutaneous T-cell lymphoma-associated antigens.

SLK CTAGE1

1.55e-0318113211149944
Pubmed

Mutations in the leukemia inhibitory factor receptor (LIFR) gene and Lifr deficiency cause urinary tract malformations.

MYH11 SLC5A2

1.55e-0318113228334964
Pubmed

Quantitative Protein Expression in the Human Retinal Pigment Epithelium: Comparison Between Apical and Basolateral Plasma Membranes With Emphasis on Transporters.

SLC46A1 CD81

1.55e-0318113231791063
Pubmed

The nuclear envelope protein Net39 is essential for muscle nuclear integrity and chromatin organization.

SV2B SV2C

1.55e-0318113233514739
CytobandEnsembl 112 genes in cytogenetic band chr17p13

MYH10 MINK1 SHBG SPNS3 CHRNE ALOX15B

2.25e-043461136chr17p13
Cytoband17p13.2

MINK1 SPNS3 CHRNE

3.47e-0455113317p13.2
CytobandEnsembl 112 genes in cytogenetic band chr1p13

SLC22A15 INKA2 GPR61 SYPL2

1.89e-032111134chr1p13
CytobandEnsembl 112 genes in cytogenetic band chr8q24

GPAA1 ADCY8 CCN4 KCNQ3 TRAPPC9

1.91e-033551135chr8q24
Cytoband8q24

ADCY8 KCNQ3

2.18e-032811328q24
GeneFamilySolute carriers

SLC22A15 SLC46A1 SLC44A4 SLC5A2 SLC5A3 SLC17A1 SLC15A4 SLC22A2 SLC5A8 MTCH1 SLC4A5 SLC6A14

2.74e-073958412752
GeneFamilyC2 domain containing|Calpains

CAPN14 CAPN3 CAPN15

4.23e-0515843975
GeneFamilyMyosin heavy chains

MYH10 MYH11

2.15e-03158421098
GeneFamilyATPase phospholipid transporting

ATP8A2 ATP8A1

2.15e-03158421210
CoexpressionGSE23321_EFFECTOR_MEMORY_VS_NAIVE_CD8_TCELL_UP

CFTR MINK1 SHBG BDKRB1 SV2B LEPROT PRAF2

1.95e-051961107M8428
CoexpressionGSE23505_UNTREATED_VS_4DAY_IL6_IL1_IL23_TREATED_CD4_TCELL_DN

SEMA4B SLC46A1 KCNQ3 LEPROT ADGRE1 PREX1 INKA1

2.15e-051991107M7853
CoexpressionGSE20366_TREG_VS_NAIVE_CD4_TCELL_DEC205_CONVERSION_DN

MYH10 HCN1 CNTNAP1 SLC22A15 C1GALT1 LEPROT SEMA4A

2.22e-052001107M4334
CoexpressionAtlasDevelopingKidney_e15.5_early proxim tubul_emap-28005_k-means-cluster#1_top-relative-expression-ranked_200

SLC44A4 SLC5A2 SLC17A1 SLC22A2 SLC5A8

2.88e-06441085gudmap_developingKidney_e15.5_early proxim tubul_200_k1
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

TNIK ATP13A4 CFTR ADCY8 ATP8A1 KCNQ3 ADGRF5 ALOX15B

2.28e-0818311386847c1252d6bb105524f812658112517fd351eab
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2|Children_(3_yrs) / Lineage, Cell type, age group and donor

TNIK ATP13A4 CFTR ADCY8 ATP8A1 KCNQ3 ADGRF5 ALOX15B

3.18e-081911138a0332a4ef629510fb313ec119195c44a3f704a80
ToppCellCOVID-19-lung-AT2|lung / Disease (COVID-19 only), tissue and cell type

ATP13A4 CFTR ATP8A1 KCNQ3 ADGRF5 SLC5A8 SLC6A14 ALOX15B

3.18e-081911138276455a64c2c3503d5048615762eb2ee37f0ac70
ToppCellEpithelial-alveolar_epithelial_cell_type_2|World / Lineage, Cell type, age group and donor

ATP13A4 CFTR ADCY8 ATP8A1 KCNQ3 ADGRF5 SLC6A14 ALOX15B

3.32e-08192113858c3737be7acce39fd2b91d70d6d7b2bbaa4f710
ToppCellIPF-Epithelial-Club|Epithelial / Disease state, Lineage and Cell class

TNIK ATP13A4 RPS6KA2 CFTR ATP8A1 KCNQ3 ADGRF5 SEMA4A

3.32e-081921138356e7a820b744a0ac87352a8d0e6e8d9fa9ed7d2
ToppCellBronchial-NucSeq-Epithelial-Epi_alveolar-AT2|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TNIK ATP13A4 CFTR SLC22A15 ATP8A1 KCNQ3 ADGRF5 ALOX15B

4.21e-081981138f948391296c261c473d339069a6d0f20ccd6f38f
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TNIK ATP13A4 RPS6KA2 CFTR ATP8A1 ADGRF5 SLC6A14 ALOX15B

4.38e-0819911382dc33804f6691d7c9682e6c9b885e945fb97fc36
ToppCellCOVID-19-Epithelial_cells-AT2|COVID-19 / group, cell type (main and fine annotations)

ATP13A4 CFTR KCNQ3 ADGRF5 SLC5A8 SLC6A14 ALOX15B

4.57e-071841137369b82f793deab672204558ae4e112cfa5aa9ccc
ToppCellCOPD-Epithelial-ATII|Epithelial / Disease state, Lineage and Cell class

TNIK CFTR ATP8A1 SEMA4A SLC5A8 SLC6A14 ALOX15B

5.10e-071871137030af361f8bdcd0aff4ec1922702833325cf74d8
ToppCellIPF-Epithelial-ATII|Epithelial / Disease state, Lineage and Cell class

TNIK ATP8A1 KCNQ3 ADGRF5 SLC5A8 SLC6A14 ALOX15B

5.29e-0718811375f5fad2773e421760e67dbace23fd1f847a2e1e0
ToppCellCOVID-19-lung-AT2|COVID-19 / Disease (COVID-19 only), tissue and cell type

ATP13A4 CFTR ATP8A1 KCNQ3 ADGRF5 SLC6A14 ALOX15B

5.68e-07190113727a1a86620fe9b5ee930d388b32352206485e6d0
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

ATP13A4 CFTR CHRM3 ATP8A1 KCNQ3 ADGRF5 SLC6A14

6.09e-071921137cc9911e182a289779a2612bc213daae5607689e7
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT2-AT2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

TNIK CFTR ATP8A1 KCNQ3 ADGRF5 SLC6A14 ALOX15B

6.31e-071931137fd4d3c0d7caf8a2fff5b3d901fc28d19a8163cdf
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

TNIK CFTR ATP8A1 KCNQ3 ADGRF5 SLC6A14 ALOX15B

6.31e-071931137f3cc7cfdbc164a4ed42f87647111522b7d393bcb
ToppCellParenchymal-NucSeq-Epithelial-Epi_alveolar-AT2|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TNIK CFTR SLC22A15 ATP8A1 KCNQ3 ADGRF5 ALOX15B

7.49e-0719811372e2a4e1756bba6f4fbe529559a97d2993c890b4b
ToppCellBronchial-10x5prime-Epithelial-Epi_alveolar|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ATP13A4 CFTR KCNQ3 ADGRF5 SLC5A8 SLC6A14 ALOX15B

7.74e-071991137a38a981cffa61c8444a980916de7414e689a1b63
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L2/3_IT|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MAS1 RPS6KA2 CAPN3 CD163 CCN4 PREX1

2.16e-061481136d5cace5605bff2bb8248fadb51f2dad7539930ba
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Adenocarcinoma_Mixed_Subtype-7|TCGA-Lung / Sample_Type by Project: Shred V9

SLC44A4 ELFN2 TSPAN3 SLC5A2 KCNQ3 ADGRF5

4.66e-0616911365f522a10b6ec24a353f53bec2f779a81cd5f9581
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYH11 ADCY8 INKA2 ADGRG6 CCN4 CD81

6.48e-06179113656db12467b445f2b8ef92af50779eeab10413eb2
ToppCellCOPD-Epithelial-ATII|World / Disease state, Lineage and Cell class

ATP13A4 CFTR KCNQ3 ADGRF5 SLC5A8 SLC6A14

7.35e-0618311368e9aab4eeec2e282c2cab9bfca6dbf40d660c7b9
ToppCellIPF-Epithelial-ATII|IPF / Disease state, Lineage and Cell class

ATP13A4 KCNQ3 ADGRF5 SLC5A8 SLC6A14 ALOX15B

7.82e-061851136563b4e6d92bb5d77a3829556116a8e99aebac615
ToppCellStriatum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_1-MURAL_Mural.Rgs5Acta2.Cnn1_(Mural.Rgs5Acta2.Cnn1)-|Striatum / BrainAtlas - Mouse McCarroll V32

MYH11 SLC44A4 CCN4 ASB10 SLC22A2

7.92e-0610711355907b9632c88d48f293c3c6d37b7ef831fbcdd86
ToppCellStriatum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_1-MURAL_Mural.Rgs5Acta2.Cnn1_(Mural.Rgs5Acta2.Cnn1)|Striatum / BrainAtlas - Mouse McCarroll V32

MYH11 SLC44A4 CCN4 ASB10 SLC22A2

7.92e-061071135d4807f008619dfd3e215d602df0d02b135b1ac37
ToppCellStriatum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_1|Striatum / BrainAtlas - Mouse McCarroll V32

MYH11 SLC44A4 CCN4 ASB10 SLC22A2

7.92e-0610711353f24de1afbfd070f9db11c9acd02b90e5eb2511d
ToppCellIPF-Epithelial-ATII|World / Disease state, Lineage and Cell class

ATP13A4 KCNQ3 ADGRF5 SLC5A8 SLC6A14 ALOX15B

8.06e-0618611366a4ff2da0af0f5e590d9f9daa5b5e9ac8c868947
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TNIK SLC44A4 ADGRG6 SLC17A1 KCNQ3 SLC5A8

8.06e-061861136f28d72b47624b69a580b4429e2be560a26898591
ToppCellControl-Epithelial-ATII|World / Disease state, Lineage and Cell class

ATP13A4 CFTR KCNQ3 ADGRF5 SLC5A8 SLC6A14

8.06e-061861136f4b6e401e19a71beddc73d8a1e08359f7c4025cf
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ATP13A4 RPS6KA2 CFTR ATP8A1 ADGRF5 ALOX15B

8.31e-0618711365df9e1f5ca32217af255e76e6fb5afa346337811
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2-D175|Adult / Lineage, Cell type, age group and donor

ATP13A4 RPS6KA2 CFTR CHRM3 KCNQ3 ADGRF5

8.57e-061881136ec38def1fdbb34ed9b30244806975bd5a4370164
ToppCellAdult|World / Lineage, Cell type, age group and donor

SEMA4B SLC22A15 KCNQ3 SLC5A8 SLC6A14 ALOX15B

8.83e-0618911365cd285bfad973125d46d704fec18b21266a63379
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYH11 ADCY8 INKA2 ADGRG6 CCN4 CD81

8.83e-061891136ca3a04c202afc32aa11d17154066ef7dc6d01405
ToppCellPND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADCY8 INKA2 ADGRG6 CCN4 SLC35F6 CD81

9.10e-06190113610b02c62e72bfea9767e3e751011436925da823e
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2-D122|Adult / Lineage, Cell type, age group and donor

RPS6KA2 ATP8A1 KCNQ3 ADGRF5 SLC5A8 ALOX15B

9.66e-06192113606013a07e3a873b1d1c0451643c528593ac32a9c
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2|Adult / Lineage, Cell type, age group and donor

CFTR ATP8A1 KCNQ3 ADGRF5 SLC6A14 ALOX15B

9.95e-061931136738f4f0a9ddde2432b429ab46838e353b1790589
ToppCellPND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYH11 ADCY8 INKA2 ADGRG6 CCN4 CD81

1.02e-0519411366a4e7f1bf67bad94cd8c472e7c66798b0c25ba01
ToppCellControl-Epithelial-ATII|Epithelial / Disease state, Lineage and Cell class

TNIK ATP8A1 ADGRF5 SEMA4A SLC6A14 ALOX15B

1.02e-051941136a01de094f7bfd099bcbb2f94224690a2efb887b4
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NBEAL1 RPS6KA2 TSPAN3 KCNQ3 SLC6A14 ALOX15B

1.09e-051961136a6a52cafd7c9994bc3d2f68b15a1491cd96ef908
ToppCellPND10-Mesenchymal|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYH10 MYH11 TSPAN3 ADGRG6 CCN4 CD81

1.09e-051961136ace167a40adb7022b365be3c2b1cbd4ba963739a
ToppCellAT2_cells-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

TSPAN3 KCNQ3 ADGRF5 SLC5A8 SLC6A14 ALOX15B

1.12e-05197113642e49a8ce3118db6c2fd620d70c480b75143c828
ToppCellproximal-Epithelial-Signaling_Alveolar_Epithelial_Type_2-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CFTR CAPN3 ATP8A1 CD81 ADGRF5 SLC6A14

1.22e-0520011367bd76884fcffdbd9b8d24f5b6b5187ad3963da5f
ToppCellParenchyma_COVID-19-Epithelial-TX-AT2-1|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

ATP13A4 CFTR ATP8A1 ADGRF5 SLC6A14 ALOX15B

1.22e-052001136cf1991853e10c562edae9a0d71a209f35b07db80
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-AT2-2|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

ATP13A4 ATP8A1 KCNQ3 ADGRF5 SLC6A14 ALOX15B

1.22e-052001136acc771a902cf2f060c3eb9aedb72a256f5778a6c
ToppCellParenchyma_COVID-19-Epithelial-TX-AT2-2|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

ATP13A4 ATP8A1 KCNQ3 ADGRF5 SLC6A14 ALOX15B

1.22e-052001136ceb613ac6cdf0e3e6bb3f04d89034e18a524cefb
ToppCellTracheal-NucSeq-Endothelial-Endothelia_vascular-VE_alveolar_capillary_Car4_aerocyte|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

RPS6KA2 RHBDD2 SLC5A2 OR52E5 ADGRF5 PREX1

1.22e-052001136fe493b0454a20498e9ada482bf55de64519f6c35
ToppCellproximal-Epithelial-Signaling_Alveolar_Epithelial_Type_2|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CFTR CAPN3 ATP8A1 CD81 ADGRF5 SLC6A14

1.22e-052001136af57f837eb7f988d24fc4612d16d68121498f0b0
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-AT2-1-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ATP13A4 CFTR ATP8A1 ADGRF5 SLC6A14 ALOX15B

1.22e-0520011367618ae284625c5c121bcc00eb9f07e5b1e3adf23
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-AT2-2-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ATP13A4 ATP8A1 KCNQ3 ADGRF5 SLC6A14 ALOX15B

1.22e-052001136eb44d1f80ecaac3a022cd04ab16dc36151e45488
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-AT2-1|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

ATP13A4 CFTR ATP8A1 ADGRF5 SLC6A14 ALOX15B

1.22e-05200113623b319bf7e5ae03e5baa777c951da9bfc97cca8c
ToppCellproximal-3-Epithelial-Signaling_Alveolar_Epithelial_Type_2|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CFTR CAPN3 ATP8A1 CD81 ADGRF5 SLC6A14

1.22e-0520011369c7859659843b1566bdf623b269b5e166c89d38c
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L2/3_IT-L2/3_IT_ALM_Sla|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MAS1 RPS6KA2 CAPN3 CD163 PREX1

2.19e-051321135ddebc0b233fdbb73ceb70187945bbed8fd273f2a
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L2/3_IT-L2/3_IT_ALM_Macc1_Lrg1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MAS1 RPS6KA2 CAPN3 CCN4 PREX1

3.11e-051421135d08e1880425d285c4433014fe0242ac7ff7734af
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

MAS1 TGM3 SV2B TTC22 LTK

3.22e-0514311355fb5a4ea93e5cce55d427e3b4a50a979504fad3c
ToppCell3'_v3-bone_marrow-Hematopoietic_progenitors-Progenitor|bone_marrow / Manually curated celltypes from each tissue

SPNS3 CHRM3 ADGRG6 NYNRIN INKA1

3.92e-051491135078e1e5765e476ba85c23fb8f6892b6698cbcbdb
ToppCellfacs-Marrow-T_cells-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MINK1 CNTNAP1 CHRNE CCN4 ADGRE1

4.88e-0515611355caefdc6cc86f2ac52abe8c8da821db14f476915
ToppCellfacs-Marrow-T_cells-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MINK1 CNTNAP1 CHRNE CCN4 ADGRE1

4.88e-051561135758f57dc10fc5cad200bf5b310c10ec9b1405f23
ToppCellPosterior_cortex|World / BrainAtlas - Mouse McCarroll V32

CHRM3 INKA2 TGM3 SV2B LTK

5.34e-05159113518e9fe2efbe0bca7c3990f3b12b6f549e2c1263a
ToppCellfacs-Limb_Muscle-forelimb_and_hindlimb|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CAPN3 ADCY8 TTC22 SEMA4A CAPN15

5.34e-051591135f7803f7b4e0379ae8256ec53110833bedee7db98
ToppCellfacs-Limb_Muscle-forelimb_and_hindlimb-18m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CAPN3 ADCY8 TTC22 SEMA4A CAPN15

5.34e-0515911356e2d38e78d2ef7803e8bb154b5c788bf62a41045
ToppCell368C-Epithelial_cells-Epithelial-A_(AT2)-|368C / Donor, Lineage, Cell class and subclass (all cells)

ELFN2 ATP8A1 ADGRF5 SLC6A14 ALOX15B

6.19e-05164113585f53d184fa70e3eb1af655807f32b17ddbfb304
ToppCell343B-Epithelial_cells-Epithelial-A_(AT2)-|343B / Donor, Lineage, Cell class and subclass (all cells)

TSPAN3 ATP8A1 ADGRF5 SLC6A14 ALOX15B

6.19e-051641135beaa13a75c3bb72446c85084d75e9fe3f15fd3d4
ToppCell368C-Epithelial_cells-Epithelial-A_(AT2)|368C / Donor, Lineage, Cell class and subclass (all cells)

ELFN2 ATP8A1 ADGRF5 SLC6A14 ALOX15B

6.19e-051641135144ba070a1ede71684224cc6d4ead3b7e6a7b4c6
ToppCellE16.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2-AT1/AT2_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFTR SLC44A4 ATP8A1 SLC4A5 SLC6A14

6.19e-051641135fe11fcce4ba7f44ba2989ea3705916b67e75f8e7
ToppCellE16.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFTR SLC44A4 ATP8A1 SLC4A5 SLC6A14

6.19e-051641135b6beb8548ac0dd07e8a580a938e5ee4bf25a3c1f
ToppCell343B-Epithelial_cells-Epithelial-A_(AT2)|343B / Donor, Lineage, Cell class and subclass (all cells)

TSPAN3 ATP8A1 ADGRF5 SLC6A14 ALOX15B

6.19e-051641135d005cfd821b87548b075120bffe65a0be9860463
ToppCellnormal_Lung-Fibroblasts-Pericytes|Fibroblasts / Location, Cell class and cell subclass

MYH11 INKA2 ADGRG6 ADGRF5 LTK

7.33e-051701135d69c0ea4cb6b204f19d0a5d2164afb42184779ac
ToppCelldroplet-Lung-nan-18m-Myeloid-Interstitial_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM202 CD163 CD81 ADGRE1 CD276

7.54e-0517111357ca404539344e14dcd90c746c9122f713a7db78b
ToppCelldroplet-Lung-nan-18m-Myeloid-lung_macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM202 CD163 CD81 ADGRE1 CD276

7.54e-051711135ab113c8e773b0af47a87aed50e96be3ba71c3c82
ToppCelldroplet-Large_Intestine-COLON:P+D-30m-Epithelial-enterocyte_of_epithelium_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANKRD37 SLC44A4 TGM3 SEMA4A SLC6A14

7.54e-051711135e7dbee63cc39230aa12e7868ec78a129160c0d22
ToppCelldroplet-Large_Intestine-COLON:P+D-30m-Epithelial-Enterocyte|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANKRD37 SLC44A4 TGM3 SEMA4A SLC6A14

7.54e-051711135b0d616699e2110ffd6cf1868ed1f1a29f824e1fc
ToppCellNasal_Brush-Epithelial-Basal_1|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

MINK1 SEMA4A PRAF2 GABBR1 INKA1

7.75e-05172113558eaadf12366701103a0d1f133462c9495fedc30
ToppCellNasal_Brush-Epithelial-Basal_1|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

MINK1 SEMA4A PRAF2 GABBR1 INKA1

7.75e-0517211354483073469001770015526303772fd54906c5d68
ToppCelldroplet-Lung-LUNG-1m-Myeloid-Interstitial_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM202 CD163 ADGRE1 ITPRIPL1 CD276

7.96e-05173113526bba58f9fb215d1d155504906cd77e8774f6936
ToppCelldroplet-Lung-LUNG-1m-Myeloid-lung_macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM202 CD163 ADGRE1 ITPRIPL1 CD276

7.96e-05173113569b404e92aad3e6dff67e75466f073f20a71f13f
ToppCellBronchial_Brush-Epithelial-Ionocytes|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

CFTR CHRNE SV2B SCN7A ADGRF5

7.96e-051731135e1de849dcd96063136bdac87e050ddbd55cabdcc
ToppCellBronchial_Brush-Epithelial-Ionocytes|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

CFTR CHRNE SV2B SCN7A ADGRF5

7.96e-051731135f2a8f4918c1fb68d98bc3f33cd624de0f0f11e06
ToppCelldroplet-Lung-18m-Hematologic-myeloid-interstitial_macrophage-interstitial_macrophage_l12|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TMEM202 CD163 CD81 ADGRE1 CD276

8.18e-05174113533e5903adb746f693433bdca11a75c508bbf50c0
ToppCelldroplet-Lung-18m-Hematologic-myeloid-interstitial_macrophage|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TMEM202 CD163 CD81 ADGRE1 CD276

8.18e-051741135ca0c2f42544092848541863c4a47b334e6828b8a
ToppCell3'-Child09-12-SmallIntestine-Epithelial-neuro-epithelial|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HCN1 OR51E1 TGM3 SV2C SLC5A8

8.63e-0517611352e1003dc373b14d27f0464d980453fdcfc1005f0
ToppCellfacs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l6-17|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TMEM202 MYH11 SLC46A1 HHAT SBK2

8.87e-0517711358abdf1d970b2f15e17e185f3e612dd5065c88757
ToppCelldroplet-Lung-18m-Mesenchymal-myofibroblast-pericyte_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MYH11 ADCY8 INKA2 ADGRG6 CCN4

9.35e-051791135f5bb4d3a27d56698473219970e764084096cc582
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TNIK ADCY8 ADGRG6 SLC17A1 SLC5A8

9.35e-05179113558ae5a97fe2a14e1c6fdeb886397eb06fdaf0428
ToppCell10x5'-lymph-node_spleen-Myeloid_Mac-Macrophage|lymph-node_spleen / Manually curated celltypes from each tissue

CAPG CAPN3 CD163 ALOX15B CD276

9.35e-051791135b4430f633711cecf793e8e76e766a66ff1eff473
ToppCell3'-Child09-12-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HCN1 OR51E1 TGM3 SV2C SLC5A8

9.35e-0517911358ce5000088b727783a0619baa16a2cd036d21f54
ToppCelldroplet-Lung-18m-Mesenchymal-myofibroblast-pericyte_cell-pericyte|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MYH11 ADCY8 INKA2 ADGRG6 CCN4

9.35e-051791135fa03ec3cc0132f977b4cb28e7b23789732375183
ToppCellControl-Epithelial_cells-AT2|Control / group, cell type (main and fine annotations)

ATP8A1 KCNQ3 ADGRF5 SLC5A8 ALOX15B

9.60e-051801135198b19e7910b4a8cc7e820c525ab357c7f99f578
ToppCellfacs-Heart-RA-3m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATP13A4 MYH11 MAS1 RRAGB TTC22

9.85e-051811135429df38438d5a7ff490c9ede34b69e2970c7ded2
ToppCellfacs-Heart-RA-3m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATP13A4 MYH11 MAS1 RRAGB TTC22

9.85e-051811135395cf5aa2d89b05328ab516b8c89401020b6d830
ToppCellAT2_cells-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

ATP8A2 RPS6KA2 ADGRF5 SLC5A8 ALOX15B

9.85e-051811135ed0ea67f0607073aedf153f8d1073b35e46127c3
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Adenocarcinoma_Mixed_Subtype|TCGA-Lung / Sample_Type by Project: Shred V9

CYB561D2 SLC44A4 ELFN2 B3GNT6 KCNQ3

9.85e-051811135c783c2ecca7ab8e07646fa92dc7d436d24939d03
ToppCellE18.5-samps|World / Age Group, Lineage, Cell class and subclass

ANKRD37 CFTR ATP8A1 SLC4A5 SLC6A14

1.01e-0418211359649f15858d1ede73e068afc59df3ac367b49687
ToppCell5'-GW_trimst-1-SmallIntestine-Mesenchymal-myocytic-SMC_(PLPP2+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYH11 ATP8A2 TECPR2 TRAPPC9 ITPRIPL1

1.01e-041821135dfde2d9950f445c6c936ac828f7210de87bb45ec
ToppCell5'-GW_trimst-1-SmallIntestine-Mesenchymal-myocytic|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYH11 ATP8A2 TECPR2 TRAPPC9 ITPRIPL1

1.01e-04182113552274af3136d4fd4a495f5882618444661421f0f
ToppCellPCW_05-06-Neuronal-Neuronal_SCP-neuro_SCP_(0)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

TNIK ADGRG6 ATP8A1 METRN PREX1

1.04e-041831135f517215ff45dec914af52dfdbc4579c19654c3aa
ToppCellCOVID-19-kidney-PCT-S1|kidney / Disease (COVID-19 only), tissue and cell type

TNIK SLC44A4 SLC17A1 SLC22A2 SLC5A8

1.06e-04184113551ed1ebfdef45149541917c66cbacad87072e51f
ToppCellP28-Mesenchymal-developing_mesenchymal_cell-mesenchymal_myogenic_precursor_(Axin2+)|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ADCY8 ADGRG6 CCN4 SLC35F6 CD81

1.06e-04184113523c24ab5786af33d605bc445d06117b9da6c6331
ToppCellfacs-Lung-24m-Mesenchymal-myofibroblast-pericyte_cell-pericyte|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MYH11 ADCY8 INKA2 ADGRG6 ASB10

1.09e-041851135a6cd90f8f30c7bdf66958cf403e73c193aa32f5e
ToppCellsystemic_lupus_erythematosus-managed-Hematopoietic-progenitor_cell-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

CHRM3 ADGRG6 SV2B NYNRIN INKA1

1.09e-0418511352c07991e0907ded67e21ab2e66be21695842ed01
ToppCellCOVID-19-Epithelial_cells-Airway_club|COVID-19 / group, cell type (main and fine annotations)

ATP13A4 CFTR KCNQ3 ADGRF5 SLC4A5

1.09e-041851135cfe6fd73d817e173fe803bc1683c291d9bcb8608
ToppCellfacs-Lung-24m-Mesenchymal-myofibroblast-pericyte_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MYH11 ADCY8 INKA2 ADGRG6 ASB10

1.09e-0418511355053f932e2adfcf4d6faaecff2999ac53d8d7aa5
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.4.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NBEAL1 TSPAN3 KCNQ3 ADGRF5 SLC6A14

1.09e-0418511357460387f48f33674330bd53b759681b264228f5a
Diseasemegacystis-microcolon-intestinal hypoperistalsis syndrome (implicated_via_orthology)

MYH11 CHRM3

1.40e-0521112DOID:0060610 (implicated_via_orthology)
DiseaseX-12798 measurement

SLC17A1 SLC22A2

1.39e-0451112EFO_0021335
Diseasecoronary artery disease

SLK MYH11 NBEAL1 HCN1 CFTR C1GALT1 SPNS3 EPG5 HHAT SLC22A2 OR52E4 MTCH1 PREX1 GABBR1

1.58e-04119411114EFO_0001645
Diseasewaist circumference

RPS6KA2 CFTR ADCY8 B3GNT6 GPR61 PXDNL SLC22A2 PREX1

2.24e-044291118EFO_0004342
Diseaselethal congenital contracture syndrome (is_implicated_in)

CNTNAP1 ADGRG6

2.91e-0471112DOID:0060558 (is_implicated_in)
Diseasedifferentiated thyroid carcinoma

SLK ADGRG6 KCNQ3

3.11e-04351113EFO_1002017
Diseasecreatinine measurement, chronic kidney disease

WDR37 SLC22A2 SYPL2

3.11e-04351113EFO_0003884, EFO_0004518
DiseaseWNT1-inducible-signaling pathway protein 1 measurement

SLC46A1 CCN4

6.19e-04101112EFO_0008321
Diseasegout

CFTR SLC17A1 SV2B PXDNL ASB10

8.91e-041961115EFO_0004274
Diseasecognitive inhibition measurement

ADGRG6 TGM3 PXDNL

8.93e-04501113EFO_0007969
Diseaselifestyle measurement, alcohol consumption measurement

ATP8A2 RHBDD2 ADCY8 KCNQ3

9.51e-041151114EFO_0007878, EFO_0010724
Diseaseneuronal ceroid lipofuscinosis (implicated_via_orthology)

ATP13A4 SPNS3

1.24e-03141112DOID:14503 (implicated_via_orthology)
Diseasecongenital myasthenic syndrome (implicated_via_orthology)

CHRNE SYT8

1.63e-03161112DOID:3635 (implicated_via_orthology)
Diseasepulmonary fibrosis (is_implicated_in)

CHRM3 BDKRB1

1.63e-03161112DOID:3770 (is_implicated_in)
Diseaseesophageal carcinoma, gastric carcinoma

BDKRB1 EPG5

1.84e-03171112EFO_0000178, EFO_0002916
Diseaseglomerulonephritis (is_marker_for)

BDKRB1 CD163

2.30e-03191112DOID:2921 (is_marker_for)
Diseasemetabolite measurement, diet measurement

SLC44A4 SLC22A2 GABBR1

2.46e-03711113EFO_0004725, EFO_0008111
DiseaseAntihypertensive use measurement

MYH11 ADCY8 PXDNL SEMA4A PREX1

3.33e-032651115EFO_0009927
Diseaseepilepsy (implicated_via_orthology)

TNIK MINK1 BDKRB1 SCN7A

3.40e-031631114DOID:1826 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
LNLIFWGAAGILCYV

TSPAN3

16

O60637
NFLGAILNILWCDFD

ADCY8

796

P40145
LACVILEGLNWGFAK

EPG5

891

Q9HCE0
VRGCFWEDFIDLGLQ

BDKRB1

281

P46663
LFCILLAAVSGAEGW

CNTNAP1

6

P78357
WELLQASAFCGLGFL

CFTR

216

P13569
LVLCSAFLLLWQGEG

CTAGE1

56

Q9HC47
LDLWGVVSCDRNGFQ

ATP13A4

496

Q4VNC1
LLDGWITSFNVDGLC

ADGRG6

916

Q86SQ4
LAFWQAVLAGDVGCV

ASB10

56

Q8WXI3
LGNLACDLWLAIDYV

CHRM3

136

P20309
VAAWCIGEYGDLLLA

AP1G2

476

O75843
GIIDFQRLWCDYLDG

ANGPTL5

201

Q86XS5
AALGALWFCLTGALE

CD276

16

Q5ZPR3
DGLGFSRQVLWINAC

CCN4

326

O95388
LFACEVAAGIWGFVN

CD81

101

P60033
GFSGQILFERWCIGL

ATP8A1

881

Q9Y2Q0
GFSGQILFERWCIGL

ATP8A2

901

Q9NTI2
GNALDNICFWAALVL

CHRNE

451

Q04844
LDLCQGIVGDCWFLA

CAPN14

91

A8MX76
GIVGDCWFLAALQAL

CAPN14

96

A8MX76
HLAAGSGLACFLLWQ

ANKRD37

36

Q7Z713
AWFCLDQDQLTLGIA

NBEAL1

596

Q6ZS30
QLACLDEAGNLFVWR

EDC4

191

Q6P2E9
NLAGQLWFGAECLAA

ZFYVE28

96

Q9HCC9
QGLLGNCWFLSALAV

CAPN15

546

O75808
ALWALVTFYGGDCQL

PAXIP1

116

Q6ZW49
CVNAQWLGDILLGNF

PAXIP1

766

Q6ZW49
IFWFNLQEISFGGCL

OR52E4

86

Q8NGH9
LVLGDNCFADLVHNW

INKA1

186

Q96EL1
WGACGLVLAGNAVIF

LEPROT

96

O15243
QYCLADAWVAEIGLA

SLC46A1

326

Q96NT5
AVVLLAVGGQFLLCW

GPR61

286

Q9BZJ8
LAPALAVGQFAACWL

GPR62

241

Q9BZJ7
GFVENGILLWFLCFR

MAS1

46

P04201
EGWQLFLAALAQGVL

GPAA1

576

O43292
VLGDNVFADLVGNWL

INKA2

156

Q9NTI7
QLALACAEGAVEWLY

METRN

46

Q9UJH8
FVCQARLWLLGLGFS

GABBR1

661

Q9UBS5
IFGAEFALRIWAAGC

KCNQ3

166

O43525
QLLVWFGAAGAILCS

LTK

6

P29376
GLEEAQFWLAFPLCS

OR51E1

21

Q8TCB6
NGAWFLCLLVANVPD

INTS2

206

Q9H0H0
GFLGRACDLHLWENQ

MEGF8

196

Q7Z7M0
CWLLGAADGLLQAVV

OR2T33

146

Q8NG76
QLVFCSWLGGFLAIL

OR6C4

141

Q8NGE1
IGCSEQQEAWFALDL

NUDT13

96

Q86X67
SCWTLGGLALAQVLF

HHAT

281

Q5VTY9
NLWNTGLFCLFLVFE

ITPRIPL1

111

Q6GPH6
CDLMWLGELLQGFAQ

PXDNL

186

A1KZ92
AGFDPLILLCNSWID

ASB3

401

Q9Y575
WDGCLQFLVPLLQDF

HCN1

311

O60741
WNFGSLLGACLILQI

MT-CYB

31

P00156
VPCFALDGQWILNSF

MBTPS2

461

O43462
IFLGAQGFFLDCLAW

KHNYN

91

O15037
SWLEGAVLEQIGLCF

CUL9

1611

Q8IWT3
WVLALGQCVLAGAFA

SLC44A4

456

Q53GD3
WLNFLTFLCGSAIGF

C1GALT1

6

Q9NS00
FILDLGQNIFAWCGG

CAPG

166

P40121
CLLVGVSFLALQQWF

B3GNT6

16

Q6ZMB0
IWFDDLICNGNESAL

CD163

221

Q86VB7
ICQGELGDCWFLAAI

CAPN3

121

P20807
LLNECVGTAYWALAG

SLC22A15

186

Q8IZD6
SNLVLFLNGAPFCWE

SLC15A4

56

Q8N697
AACLASVFIPGDLQW

SLC22A2

416

O15244
QPALDAWALGVLLFC

SBK2

241

P0C263
GQAGLLAVLWAGLQC

CYB561D2

121

O14569
TNALIVDLWGLQEGC

KIF28P

771

B7ZC32
WNFIDFGLDLQPCID

MYH10

506

P35580
AGLLFWAGQAVNALI

R3HDML

11

Q9H3Y0
FLGAQGLFLDCLCWS

NYNRIN

91

Q9P2P1
NLGCVFNAQGEIWLA

OGT

196

O15294
EILCAALWGVNLLVG

MINK1

1021

Q8N4C8
IFWFNLGEIAFGACI

OR52E5

86

Q8NH55
CYQWLEGAGTLVLQE

ALOX15B

106

O15296
LGDVVFLWGCNLLAH

MTCH1

261

Q9NZJ7
VVYWVVCALGLAGNL

RXFP3

86

Q9NSD7
QQWGCLQLSLEFDFG

SYT8

116

Q8NBV8
VLFGFINFFLWAGNC

SYPL2

216

Q5VXT5
ENNLWILIEFCAGGA

SLK

101

Q9H2G2
IIQECGHGRFQWALF

SV2C

141

Q496J9
ECGHGRFQWILFFVL

SV2B

101

Q7L1I2
AWICGNLAGQLSDFF

SLC17A1

311

Q14916
LLIVQDGVGGLYQCW

SEMA4A

611

Q9H3S1
LGEFQCWSLEEGFQQ

SEMA4B

651

Q9NPR2
CFLGNEFVAWLLEIG

PREX1

441

Q8TCU6
FCLNGLWAQGQRLDV

SHBG

361

P04278
GFAVGAWEFNALLLL

SLC5A3

76

P53794
ALALNQVTGFDLWGA

SLC5A8

151

Q8N695
WNFGQFEEDILSICL

TGM3

176

Q08188
FAQLFILGCSWVLGI

ADGRE1

801

Q14246
VFQGLFILLFGCLWD

ADGRF5

1256

Q8IZF2
WNFIDFGLDLQPCIE

MYH11

506

P35749
FNSEILCAALWGVNL

TNIK

1046

Q9UKE5
LAFWQDLGNLVADGC

M6PR

226

P20645
YVFLGLGELLLSCNW

SPNS3

371

Q6ZMD2
AGFEWNALFVVLLLG

SLC5A2

96

P31639
LLVLWVAGGACTFLF

PRAF2

111

O60831
LLCGAIIIWRFAGNF

RHBDD2

76

Q6NTF9
ELWNQGAGLLAACFI

STT3B

191

Q8TCJ2
EELIWTGRFFGGLCL

SLC4A5

486

Q9BY07
VRFLGNLVLNLWDCG

RRAGB

111

Q5VZM2
NLVLNLWDCGGQDTF

RRAGB

116

Q5VZM2
ERHLGLVSCFFQEGW

TECPR2

286

O15040
GFINLCDALNAWQLV

ATIC

236

P31939
GWEAFHALQILGFLI

SLC35F6

311

Q8N357
VFRCLGSWFNLGVLD

TNPO3

201

Q9Y5L0
LFTCGFDRQAIGWNI

WDR37

471

Q9Y2I8
CLFQVAIFAGWDGML

SCN7A

1426

Q01118
VNDFLWLGAALEGLC

TRAPPC9

236

Q96Q05
NFALVATLGFWCEAE

ZNF304

46

Q9HCX3
RQLVTGCADGQLWIF

WDR27

221

A2RRH5
LIDHFCAGWGILIAA

SLC6A14

476

Q9UN76
KNGLELYAGLWTLCN

TMEM202

86

A6NGA9
GFGCLLEALLAQWSQ

TTC22

471

Q5TAA0
CDLFGFLAWLVVFNN

ELFN2

191

Q5R3F8
QGYDAACDIWSLGIL

RPS6KA2

586

Q15349