Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	benzodiazepine receptor binding	RIMBP3 RIMBP3C RIMBP3B	1.70e-06	5	112	3	GO:0030156
GeneOntologyMolecularFunction	inositol 1,4,5-trisphosphate-gated calcium channel activity	ITPR1 ITPR2	9.32e-05	3	112	2	GO:0005220
GeneOntologyMolecularFunction	importin-alpha family protein binding	GOLGA6C GOLGA6B GOLGA6A	2.12e-04	21	112	3	GO:0061676
GeneOntologyBiologicalProcess	endomembrane system organization	SPTB LRRK2 GOLGA6C PI4K2A UBL4A CC2D1A GOLGA6B GOLGA6A XKR6 HUWE1 AP3B1 SNX19 AKAP9 TMF1 MAPK3 HPS5	7.02e-07	672	112	16	GO:0010256
GeneOntologyBiologicalProcess	Golgi organization	LRRK2 GOLGA6C PI4K2A GOLGA6B GOLGA6A HUWE1 AKAP9 MAPK3	3.80e-06	168	112	8	GO:0007030
GeneOntologyBiologicalProcess	fertilization	AP3B1 ITPR1 RIMBP3 SPTBN4 HOXA9 TUBGCP3 RIMBP3C RIMBP3B ALDOA	1.36e-05	263	112	9	GO:0009566
GeneOntologyBiologicalProcess	microtubule nucleation	GOLGA6C GOLGA6B GOLGA6A AKAP9 TUBGCP3	1.44e-05	57	112	5	GO:0007020
GeneOntologyBiologicalProcess	organelle inheritance	GOLGA6C GOLGA6B GOLGA6A MAPK3	1.53e-05	28	112	4	GO:0048308
GeneOntologyBiologicalProcess	Golgi inheritance	GOLGA6C GOLGA6B GOLGA6A MAPK3	1.53e-05	28	112	4	GO:0048313
GeneOntologyBiologicalProcess	cell morphogenesis	SIPA1L3 LAMA1 LRRK2 GOLGA6C CC2D1A GOLGA6B GOLGA6A AP3B1 ADARB1 ADCY1 ITPR1 SPTBN4 TTC8 NKX2-8 DST CELSR3 ALDOA MUL1 ARAP1	2.19e-05	1194	112	19	GO:0000902
GeneOntologyBiologicalProcess	endoplasmic reticulum to Golgi vesicle-mediated transport	PDCD6 LRRK2 GOLGA6C GOLGA6B GOLGA6A SCAP TRAPPC10	2.61e-05	159	112	7	GO:0006888
GeneOntologyBiologicalProcess	neuromuscular synaptic transmission	ADARB1 RIMBP3 RIMBP3C RIMBP3B	4.24e-05	36	112	4	GO:0007274
GeneOntologyBiologicalProcess	neuron projection development	RASGRF1 LAMA1 LRRK2 GOLGA6C DDX56 CC2D1A GOLGA6B GOLGA6A ADARB1 ADCY1 GFAP ITPR1 SPTBN4 TTC8 NKX2-8 DST CELSR3 PJVK MUL1	5.96e-05	1285	112	19	GO:0031175
GeneOntologyBiologicalProcess	protein homotetramerization	GOLGA6C GOLGA6B GOLGA6A ITPR1 ALDOA	6.25e-05	77	112	5	GO:0051289
GeneOntologyBiologicalProcess	synaptic signaling	GABRP BEST1 RASGRF1 FXR2 LRRK2 PCDHB3 ADARB1 ADCY1 GFAP ITPR1 RIMBP3 AKAP9 RIMBP3C MAPK3 RIMBP3B ALG13	7.44e-05	976	112	16	GO:0099536
GeneOntologyBiologicalProcess	Golgi vesicle transport	PDCD6 LRRK2 GOLGA6C GOLGA6B GOLGA6A ASB15 SCAP TRAPPC10 RAB11FIP3	9.80e-05	339	112	9	GO:0048193
GeneOntologyBiologicalProcess	neuron projection morphogenesis	LAMA1 LRRK2 GOLGA6C CC2D1A GOLGA6B GOLGA6A ADARB1 ADCY1 SPTBN4 TTC8 NKX2-8 DST CELSR3 MUL1	1.13e-04	802	112	14	GO:0048812
GeneOntologyBiologicalProcess	Golgi disassembly	GOLGA6C GOLGA6B GOLGA6A	1.20e-04	18	112	3	GO:0090166
GeneOntologyBiologicalProcess	plasma membrane bounded cell projection morphogenesis	LAMA1 LRRK2 GOLGA6C CC2D1A GOLGA6B GOLGA6A ADARB1 ADCY1 SPTBN4 TTC8 NKX2-8 DST CELSR3 MUL1	1.41e-04	819	112	14	GO:0120039
GeneOntologyBiologicalProcess	positive regulation of protein glycosylation	GOLGA6C GOLGA6B GOLGA6A	1.42e-04	19	112	3	GO:0060050
GeneOntologyBiologicalProcess	anterograde trans-synaptic signaling	GABRP BEST1 RASGRF1 FXR2 LRRK2 PCDHB3 ADARB1 ADCY1 GFAP RIMBP3 AKAP9 RIMBP3C MAPK3 RIMBP3B ALG13	1.54e-04	931	112	15	GO:0098916
GeneOntologyBiologicalProcess	chemical synaptic transmission	GABRP BEST1 RASGRF1 FXR2 LRRK2 PCDHB3 ADARB1 ADCY1 GFAP RIMBP3 AKAP9 RIMBP3C MAPK3 RIMBP3B ALG13	1.54e-04	931	112	15	GO:0007268
GeneOntologyBiologicalProcess	cell projection morphogenesis	LAMA1 LRRK2 GOLGA6C CC2D1A GOLGA6B GOLGA6A ADARB1 ADCY1 SPTBN4 TTC8 NKX2-8 DST CELSR3 MUL1	1.54e-04	826	112	14	GO:0048858
GeneOntologyBiologicalProcess	trans-synaptic signaling	GABRP BEST1 RASGRF1 FXR2 LRRK2 PCDHB3 ADARB1 ADCY1 GFAP RIMBP3 AKAP9 RIMBP3C MAPK3 RIMBP3B ALG13	1.69e-04	939	112	15	GO:0099537
GeneOntologyBiologicalProcess	response to electrical stimulus involved in regulation of muscle adaptation	MYOG FBXO32	1.74e-04	4	112	2	GO:0014878
GeneOntologyBiologicalProcess	cell morphogenesis involved in neuron differentiation	LAMA1 LRRK2 GOLGA6C CC2D1A GOLGA6B GOLGA6A ADARB1 ADCY1 SPTBN4 TTC8 NKX2-8 DST CELSR3	2.11e-04	748	112	13	GO:0048667
GeneOntologyBiologicalProcess	sexual reproduction	RAD51B LRRK2 GOLGA6C GOLGA6B GOLGA6A AP3B1 ITPR1 RIMBP3 SPTBN4 HOXA9 AXDND1 AKAP9 TUBGCP3 TMF1 TNK2 RIMBP3C RIMBP3B ALDOA	2.43e-04	1312	112	18	GO:0019953
GeneOntologyBiologicalProcess	Golgi ribbon formation	GOLGA6C GOLGA6B GOLGA6A	2.55e-04	23	112	3	GO:0090161
GeneOntologyBiologicalProcess	axonogenesis	LAMA1 GOLGA6C GOLGA6B GOLGA6A ADARB1 ADCY1 SPTBN4 TTC8 NKX2-8 DST CELSR3	2.59e-04	566	112	11	GO:0007409
GeneOntologyBiologicalProcess	negative regulation of protein binding	LRRK2 GOLGA6C GOLGA6B GOLGA6A MAPK3	2.83e-04	106	112	5	GO:0032091
GeneOntologyBiologicalProcess	regulation of protein glycosylation	GOLGA6C GOLGA6B GOLGA6A	2.90e-04	24	112	3	GO:0060049
GeneOntologyBiologicalProcess	microtubule polymerization or depolymerization	GOLGA6C GOLGA6B GOLGA6A AKAP9 TUBGCP3 KIF18B	3.13e-04	168	112	6	GO:0031109
GeneOntologyBiologicalProcess	neuron development	RASGRF1 LAMA1 LRRK2 GOLGA6C DDX56 CC2D1A GOLGA6B GOLGA6A ADARB1 ADCY1 GFAP ITPR1 SPTBN4 TTC8 NKX2-8 DST CELSR3 PJVK MUL1	3.21e-04	1463	112	19	GO:0048666
GeneOntologyBiologicalProcess	protein tetramerization	GOLGA6C GOLGA6B GOLGA6A ITPR1 ALDOA	3.80e-04	113	112	5	GO:0051262
GeneOntologyBiologicalProcess	Golgi localization	GOLGA6C GOLGA6B GOLGA6A	4.15e-04	27	112	3	GO:0051645
GeneOntologyBiologicalProcess	vesicle organization	PDCD6 PI4K2A CC2D1A AP3B1 SNX19 SCAP TRAPPC10 TMF1 HPS5	4.39e-04	415	112	9	GO:0016050
GeneOntologyBiologicalProcess	microtubule polymerization	GOLGA6C GOLGA6B GOLGA6A AKAP9 TUBGCP3	4.46e-04	117	112	5	GO:0046785
GeneOntologyBiologicalProcess	meiotic spindle assembly	GOLGA6C GOLGA6B GOLGA6A	4.62e-04	28	112	3	GO:0090306
GeneOntologyBiologicalProcess	supramolecular fiber organization	MYO1A SPTB GOLGA6C GOLGA6B GOLGA6A GFAP MYO5C SPTBN4 TTC8 AKAP9 TUBGCP3 KIF18B ALDOA ARAP1	6.80e-04	957	112	14	GO:0097435
GeneOntologyBiologicalProcess	axon development	LAMA1 GOLGA6C GOLGA6B GOLGA6A ADARB1 ADCY1 SPTBN4 TTC8 NKX2-8 DST CELSR3	7.44e-04	642	112	11	GO:0061564
GeneOntologyCellularComponent	Golgi apparatus subcompartment	LRRK2 GOLGA6C PI4K2A GOLGA6B GOLGA6A AP3B1 AKAP9 RIC1 ARAP1 RAB11FIP3	1.26e-04	443	111	10	GO:0098791
GeneOntologyCellularComponent	COPII-coated ER to Golgi transport vesicle	PDCD6 GOLGA6C GOLGA6B GOLGA6A SCAP	3.03e-04	110	111	5	GO:0030134
GeneOntologyCellularComponent	cell body	MYO1A RASGRF1 LRRK2 GOLGA6C PI4K2A GOLGA6B GOLGA6A GFAP ITPR1 SPTBN4 AKAP9 PJVK TNK2 MUL1	4.05e-04	929	111	14	GO:0044297
GeneOntologyCellularComponent	postsynaptic recycling endosome membrane	ABHD17A RAB11FIP3	4.13e-04	6	111	2	GO:0098944
GeneOntologyCellularComponent	manchette	RIMBP3 RIMBP3C RIMBP3B	4.33e-04	28	111	3	GO:0002177
GeneOntologyCellularComponent	Golgi membrane	LRRK2 GOLGA6C PI4K2A GOLGA6B CHST9 GOLGA6A HUWE1 SCAP TMF1 RIC1 GALNT4 RAB11FIP3	4.50e-04	721	111	12	GO:0000139
GeneOntologyCellularComponent	neuronal cell body	MYO1A RASGRF1 LRRK2 GOLGA6C PI4K2A GOLGA6B GOLGA6A ITPR1 SPTBN4 AKAP9 PJVK TNK2 MUL1	4.87e-04	835	111	13	GO:0043025
GeneOntologyCellularComponent	Golgi cis cisterna	GOLGA6C GOLGA6B GOLGA6A	7.08e-04	33	111	3	GO:0000137
GeneOntologyCellularComponent	cell cortex	MYO1A SPTB STIL ITPR2 SPTBN4 DST PJVK EXOC3L1	8.24e-04	371	111	8	GO:0005938
GeneOntologyCellularComponent	platelet dense tubular network membrane	ITPR1 ITPR2	9.82e-04	9	111	2	GO:0031095
GeneOntologyCellularComponent	spectrin	SPTB SPTBN4	9.82e-04	9	111	2	GO:0008091
GeneOntologyCellularComponent	cis-Golgi network	GOLGA6C GOLGA6B GOLGA6A AKAP9	1.10e-03	85	111	4	GO:0005801
GeneOntologyCellularComponent	endosome	ANKRD13B ABHD17A PDCD6 LRRK2 PI4K2A IRAK2 CC2D1A ASB15 AP3B1 SNX19 TRAPPC10 TNK2 MAPK3 HPS5 RAB11FIP3	1.29e-03	1167	111	15	GO:0005768
GeneOntologyCellularComponent	cytoplasmic vesicle membrane	ABHD17A PHACTR2 PDCD6 LRRK2 PI4K2A IRAK2 CC2D1A ASB15 AP3B1 SNX19 DENND4C ITPR1 ITPR2 SCAP TNK2 RAB11FIP3	1.46e-03	1307	111	16	GO:0030659
GeneOntologyCellularComponent	postsynaptic endosome membrane	ABHD17A RAB11FIP3	1.49e-03	11	111	2	GO:0098895
GeneOntologyCellularComponent	platelet dense tubular network	ITPR1 ITPR2	1.49e-03	11	111	2	GO:0031094
GeneOntologyCellularComponent	cortical actin cytoskeleton	MYO1A SPTB SPTBN4 PJVK	1.53e-03	93	111	4	GO:0030864
GeneOntologyCellularComponent	Golgi cisterna membrane	GOLGA6C GOLGA6B GOLGA6A ARAP1	1.59e-03	94	111	4	GO:0032580
GeneOntologyCellularComponent	vesicle membrane	ABHD17A PHACTR2 PDCD6 LRRK2 PI4K2A IRAK2 CC2D1A ASB15 AP3B1 SNX19 DENND4C ITPR1 ITPR2 SCAP TNK2 RAB11FIP3	1.68e-03	1325	111	16	GO:0012506
GeneOntologyCellularComponent	postsynaptic recycling endosome	ABHD17A RAB11FIP3	2.10e-03	13	111	2	GO:0098837
GeneOntologyCellularComponent	somatodendritic compartment	ABHD17A MYO1A RASGRF1 FXR2 LRRK2 GOLGA6C PI4K2A GOLGA6B GOLGA6A ITPR1 SPTBN4 AKAP9 PJVK TNK2 MUL1	2.12e-03	1228	111	15	GO:0036477
GeneOntologyCellularComponent	Golgi stack	GOLGA6C GOLGA6B GOLGA6A AKAP9 ARAP1	2.20e-03	171	111	5	GO:0005795
MousePheno	abnormal acrosome morphology	BEST1 GOLGA6C GOLGA6B GOLGA6A RIMBP3 AKAP9 TMF1 RIMBP3C RIMBP3B	8.98e-07	159	91	9	MP:0008898
MousePheno	abnormal sperm head morphology	BEST1 DNAH2 GOLGA6C GOLGA6B GOLGA6A RIMBP3 AXDND1 AKAP9 TMF1 RIMBP3C RIMBP3B	9.85e-07	261	91	11	MP:0009230
MousePheno	absent acrosome	BEST1 GOLGA6C GOLGA6B GOLGA6A TMF1	1.83e-06	32	91	5	MP:0008839
MousePheno	abnormal spermiogenesis	DNAH2 GOLGA6C GOLGA6B GOLGA6A RIMBP3 AXDND1 AKAP9 TMF1 RIMBP3C RIMBP3B	3.14e-06	237	91	10	MP:0001932
MousePheno	abnormal sperm nucleus morphology	GOLGA6C GOLGA6B GOLGA6A RIMBP3 RIMBP3C RIMBP3B	8.36e-06	74	91	6	MP:0009232
MousePheno	detached sperm flagellum	BEST1 RIMBP3 RIMBP3C RIMBP3B	9.24e-06	21	91	4	MP:0008893
MousePheno	abnormal Golgi vesicle transport	LRRK2 GOLGA6C GOLGA6B GOLGA6A	1.12e-05	22	91	4	MP:0030949
MousePheno	absent sperm mitochondrial sheath	DNAH2 GOLGA6C GOLGA6B GOLGA6A	3.05e-05	28	91	4	MP:0009833
MousePheno	kinked sperm flagellum	BEST1 DNAH2 RIMBP3 RIMBP3C RIMBP3B	3.08e-05	56	91	5	MP:0009237
MousePheno	teratozoospermia	BEST1 DNAH2 GOLGA6C GOLGA6B GOLGA6A RIMBP3 AXDND1 AKAP9 TMF1 RIMBP3C RIMBP3B	6.65e-05	408	91	11	MP:0005578
MousePheno	abnormal spermatid morphology	GOLGA6C GOLGA6B GOLGA6A RIMBP3 AXDND1 TMF1 RIMBP3C RIMBP3B	8.34e-05	217	91	8	MP:0006380
MousePheno	increased alveolar macrophage number	GOLGA6C GOLGA6B GOLGA6A	9.22e-05	14	91	3	MP:0014228
MousePheno	abnormal alveolar macrophage number	GOLGA6C GOLGA6B GOLGA6A	1.15e-04	15	91	3	MP:0014227
MousePheno	globozoospermia	GOLGA6C GOLGA6B GOLGA6A AKAP9 TMF1	1.18e-04	74	91	5	MP:0002686
MousePheno	abnormal lung epithelium morphology	FRAS1 LRRK2 GOLGA6C GOLGA6B GOLGA6A NKX2-8	1.18e-04	118	91	6	MP:0006382
MousePheno	abnormal sperm flagellum morphology	BEST1 DNAH2 GOLGA6C GOLGA6B GOLGA6A RIMBP3 TMF1 RIMBP3C RIMBP3B	1.27e-04	295	91	9	MP:0008892
MousePheno	abnormal manchette morphology	RIMBP3 AXDND1 RIMBP3C RIMBP3B	2.04e-04	45	91	4	MP:0009376
MousePheno	ectopic manchette	RIMBP3 RIMBP3C RIMBP3B	2.40e-04	19	91	3	MP:0009377
MousePheno	abnormal acrosome assembly	GOLGA6C GOLGA6B GOLGA6A AKAP9 TMF1	3.30e-04	92	91	5	MP:0031354
MousePheno	slow postnatal weight gain	GOLGA6C GPAM GOLGA6B GOLGA6A TTC8 DST HELZ2	3.76e-04	205	91	7	MP:0008489
MousePheno	abnormal sperm mitochondrial sheath morphology	DNAH2 GOLGA6C GOLGA6B GOLGA6A TMF1	3.82e-04	95	91	5	MP:0009832
MousePheno	abnormal proacrosomal vesicle fusion	GOLGA6C GOLGA6B GOLGA6A	4.89e-04	24	91	3	MP:0031355
MousePheno	abnormal cilium morphology	BEST1 DNAH2 GOLGA6C GOLGA6B GOLGA6A RIMBP3 TTC8 TMF1 RIMBP3C RIMBP3B	5.01e-04	433	91	10	MP:0013202
MousePheno	immotile sperm	DNAH2 GOLGA6C GOLGA6B GOLGA6A	5.82e-04	59	91	4	MP:0020869
MousePheno	abnormal motile cilium morphology	BEST1 DNAH2 GOLGA6C GOLGA6B GOLGA6A RIMBP3 TMF1 RIMBP3C RIMBP3B	6.70e-04	370	91	9	MP:0013206
MousePheno	abnormal alveolar macrophage morphology	GOLGA6C GOLGA6B GOLGA6A	6.97e-04	27	91	3	MP:0008245
MousePheno	abnormal respiratory epithelium morphology	FRAS1 LRRK2 GOLGA6C GOLGA6B GOLGA6A TTC8 NKX2-8	8.48e-04	235	91	7	MP:0010942
MousePheno	abnormal platelet ADP level	AP3B1 HPS5	8.62e-04	7	91	2	MP:0009556
MousePheno	decreased platelet ADP level	AP3B1 HPS5	8.62e-04	7	91	2	MP:0009557
MousePheno	oligozoospermia	DNAH2 GOLGA6C GOLGA6B GOLGA6A RIMBP3 AXDND1 AKAP9 RIMBP3C RIMBP3B	8.72e-04	384	91	9	MP:0002687
Domain	InsP3_rcpt-bd	ITPR1 ITPR2	1.03e-04	3	110	2	IPR000493
Domain	GOLGA2L5	GOLGA6C GOLGA6B GOLGA6A	1.52e-04	18	110	3	PF15070
Domain	Golgin_A	GOLGA6C GOLGA6B GOLGA6A	1.52e-04	18	110	3	IPR024858
Domain	Spectrin_bsu	SPTB SPTBN4	2.05e-04	4	110	2	IPR016343
Domain	Spectrin	SPTB SPTBN4 DST	3.23e-04	23	110	3	PF00435
Domain	ACTININ_2	SPTB SPTBN4 DST	3.23e-04	23	110	3	PS00020
Domain	ACTININ_1	SPTB SPTBN4 DST	3.23e-04	23	110	3	PS00019
Domain	Actinin_actin-bd_CS	SPTB SPTBN4 DST	3.23e-04	23	110	3	IPR001589
Domain	RIH_assoc-dom	ITPR1 ITPR2	5.08e-04	6	110	2	IPR013662
Domain	Ins145_P3_rec	ITPR1 ITPR2	5.08e-04	6	110	2	PF08709
Domain	RIH_assoc	ITPR1 ITPR2	5.08e-04	6	110	2	PF08454
Domain	RIH_dom	ITPR1 ITPR2	5.08e-04	6	110	2	IPR000699
Domain	Ins145_P3_rcpt	ITPR1 ITPR2	5.08e-04	6	110	2	IPR014821
Domain	Ryanodine_recept-rel	ITPR1 ITPR2	5.08e-04	6	110	2	IPR015925
Domain	-	ITPR1 ITPR2	5.08e-04	6	110	2	1.25.10.30
Domain	RYDR_ITPR	ITPR1 ITPR2	5.08e-04	6	110	2	PF01365
Domain	Spectrin_repeat	SPTB SPTBN4 DST	6.50e-04	29	110	3	IPR002017
Domain	SPEC	SPTB SPTBN4 DST	8.71e-04	32	110	3	SM00150
Domain	Spectrin/alpha-actinin	SPTB SPTBN4 DST	8.71e-04	32	110	3	IPR018159
Domain	ARM-type_fold	DCAF1 LRRK2 HUWE1 AP3B1 ITPR1 ITPR2 XPO6 ZER1	8.92e-04	339	110	8	IPR016024
Domain	SH3_9	RIMBP3 TNK2 RIMBP3C RIMBP3B	1.16e-03	78	110	4	PF14604
Domain	MIR	ITPR1 ITPR2	1.50e-03	10	110	2	PF02815
Domain	MIR_motif	ITPR1 ITPR2	1.50e-03	10	110	2	IPR016093
Domain	MIR	ITPR1 ITPR2	1.50e-03	10	110	2	PS50919
Domain	MIR	ITPR1 ITPR2	1.50e-03	10	110	2	SM00472
Pathway	REACTOME_GOLGI_CISTERNAE_PERICENTRIOLAR_STACK_REORGANIZATION	GOLGA6C GOLGA6B GOLGA6A MAPK3	8.24e-06	23	81	4	MM14620
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	FRAS1 PIEZO1 SIPA1L3 UBL4A DDX56 CC2D1A CHD8 HUWE1 REXO1 ITPR2 SCAP DST CELSR3 XPO6 HELZ2 TNK2 ZER1 RIC1 ARAP1 RAB11FIP3	4.48e-10	1105	113	20	35748872
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	FRAS1 XRN2 LUC7L3 EPB41L4B NOA1 GPAM CHD8 AP3B1 ITPR1 DST GTF3C1 TUBGCP3 HPS5 RIC1	2.77e-08	650	113	14	38777146
Pubmed	Evidence That ITPR2-Mediated Intracellular Calcium Release in Oligodendrocytes Regulates the Development of Carbonic Anhydrase II + Type I/II Oligodendrocytes and the Sizes of Myelin Fibers.	GFAP ITPR1 ITPR2 MAPK3	1.03e-07	14	113	4	34630045
Pubmed	RIM-BP3 is a manchette-associated protein essential for spermiogenesis.	RIMBP3 RIMBP3C RIMBP3B	1.33e-07	4	113	3	19091768
Pubmed	Defining the membrane proteome of NK cells.	ABHD17A XRN2 FXR2 PI4K2A DDX56 CC2D1A HUWE1 AP3B1 ITPR1 ITPR2 GTF3C1 GYS1 TUBGCP3 HELZ2 TNK2 ALDOA MUL1	2.38e-07	1168	113	17	19946888
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	RAD51B BEST1 LUC7L3 EPB41L4B SIPA1L3 SPTB TSPYL2 DDX56 HUWE1 ADARB1 ADCY1 SPTBN4 TTC8 GTF3C1 TNK2 ZFHX3 HPS5 RIC1 ARAP1	3.25e-07	1489	113	19	28611215
Pubmed	Structure and evolution of RIM-BP genes: identification of a novel family member.	RIMBP3 RIMBP3C RIMBP3B	3.32e-07	5	113	3	17855024
Pubmed	Myogenin and class II HDACs control neurogenic muscle atrophy by inducing E3 ubiquitin ligases.	MYOG DST FBXO32	6.63e-07	6	113	3	20887891
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	SIPA1L3 CHD8 SCAP DST XPO6 HELZ2 HPS5 ARAP1	7.74e-07	225	113	8	12168954
Pubmed	Inhibition of atrogin-1/MAFbx mediated MyoD proteolysis prevents skeletal muscle atrophy in vivo.	MYOG LAMA1 FBXO32	1.16e-06	7	113	3	19319192
Pubmed	Forward genetics defines Xylt1 as a key, conserved regulator of early chondrocyte maturation and skeletal length.	GOLGA6C GOLGA6B GOLGA6A MAPK3	1.27e-06	25	113	4	24161523
Pubmed	Gestational stress induces the unfolded protein response, resulting in heart defects.	GOLGA6C GOLGA6B GOLGA6A MAPK3	1.27e-06	25	113	4	27436040
Pubmed	CFP1 Regulates Histone H3K4 Trimethylation and Developmental Potential in Mouse Oocytes.	GOLGA6C GOLGA6B GOLGA6A MAPK3	1.27e-06	25	113	4	28768200
Pubmed	Endophilin-A2 dependent VEGFR2 endocytosis promotes sprouting angiogenesis.	GOLGA6C GOLGA6B GOLGA6A GFAP	1.49e-06	26	113	4	31138815
Pubmed	CDK5RAP2 expression during murine and human brain development correlates with pathology in primary autosomal recessive microcephaly.	GOLGA6C GOLGA6B GOLGA6A GFAP	1.49e-06	26	113	4	22806269
Pubmed	PTEN dephosphorylates Abi1 to promote epithelial morphogenesis.	LAMA1 GOLGA6C GOLGA6B GOLGA6A	1.49e-06	26	113	4	32673396
Pubmed	Protein O-Glucosyltransferase 1 (POGLUT1) Promotes Mouse Gastrulation through Modification of the Apical Polarity Protein CRUMBS2.	GOLGA6C GOLGA6B GOLGA6A MEOX1	2.71e-06	30	113	4	26496195
Pubmed	Failure of epithelial tube maintenance causes hydrocephalus and renal cysts in Dlg5-/- mice.	GOLGA6C GOLGA6B GOLGA6A GFAP	3.11e-06	31	113	4	17765678
Pubmed	Adamtsl2 deletion results in bronchial fibrillin microfibril accumulation and bronchial epithelial dysplasia--a novel mouse model providing insights into geleophysic dysplasia.	GOLGA6C GOLGA6B GOLGA6A MAPK3	3.11e-06	31	113	4	25762570
Pubmed	Hermansky-Pudlak syndrome protein complexes associate with phosphatidylinositol 4-kinase type II alpha in neuronal and non-neuronal cells.	PI4K2A AP3B1 HPS5	3.94e-06	10	113	3	19010779
Pubmed	Palmitoylation regulates epidermal homeostasis and hair follicle differentiation.	GOLGA6C GOLGA6B GOLGA6A MAPK3	4.54e-06	34	113	4	19956733
Pubmed	FGF signalling regulates bone growth through autophagy.	GOLGA6C GOLGA6B GOLGA6A MAPK3	7.16e-06	38	113	4	26595272
Pubmed	The cell proliferation antigen Ki-67 organises heterochromatin.	FRAS1 XRN2 FXR2 DDX56 CHD8 DST GTF3C1 KIF18B ALDOA	8.17e-06	410	113	9	26949251
Pubmed	Globozoospermia and lack of acrosome formation in GM130-deficient mice.	GOLGA6C GOLGA6B GOLGA6A	9.33e-06	13	113	3	28055014
Pubmed	GM130 regulates pulmonary surfactant protein secretion in alveolar type II cells.	GOLGA6C GOLGA6B GOLGA6A	9.33e-06	13	113	3	33740186
Pubmed	Loss of GM130 does not impair oocyte meiosis and embryo development in mice.	GOLGA6C GOLGA6B GOLGA6A	9.33e-06	13	113	3	32873390
Pubmed	GM130, a cis-Golgi protein, regulates meiotic spindle assembly and asymmetric division in mouse oocyte.	GOLGA6C GOLGA6B GOLGA6A	9.33e-06	13	113	3	21552007
Pubmed	Loss of the golgin GM130 causes Golgi disruption, Purkinje neuron loss, and ataxia in mice.	GOLGA6C GOLGA6B GOLGA6A	9.33e-06	13	113	3	28028212
Pubmed	GOLGA2 loss causes fibrosis with autophagy in the mouse lung and liver.	GOLGA6C GOLGA6B GOLGA6A	9.33e-06	13	113	3	29128360
Pubmed	Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.	PHACTR2 LUC7L3 PIEZO1 SPTB LRRK2 CHD8 SNX19 DENND4C ZNF826P ITPR1 PTPN12 SCAP TNK2 MAP3K15 POFUT2	9.52e-06	1215	113	15	15146197
Pubmed	Cloning and characterization of a Golgin-related gene from the large-scale polymorphism linked to the PML gene.	GOLGA6B GOLGA6A	1.05e-05	2	113	2	11161787
Pubmed	ERK pathway activation bidirectionally affects visual recognition memory and synaptic plasticity in the perirhinal cortex.	RASGRF1 MAPK3	1.05e-05	2	113	2	22232579
Pubmed	Immunolocalization of type 2 inositol 1,4,5-trisphosphate receptors in cardiac myocytes from newborn mice.	ITPR1 ITPR2	1.05e-05	2	113	2	15201137
Pubmed	Identification of MAFbx as a myogenin-engaged F-box protein in SCF ubiquitin ligase.	MYOG FBXO32	1.05e-05	2	113	2	19631210
Pubmed	Sulphide signalling potentiates apoptosis through the up-regulation of IP3 receptor types 1 and 2.	ITPR1 ITPR2	1.05e-05	2	113	2	23582047
Pubmed	A polymorphic genomic duplication on human chromosome 15 is a susceptibility factor for panic and phobic disorders.	GOLGA6B GOLGA6A	1.05e-05	2	113	2	11509185
Pubmed	Human chromosome 15q11-q14 regions of rearrangements contain clusters of LCR15 duplicons.	GOLGA6B GOLGA6A	1.05e-05	2	113	2	11896453
Pubmed	Type 1 and 2 IP3 receptors respond differently to catecholamines and stress.	ITPR1 ITPR2	1.05e-05	2	113	2	19120126
Pubmed	An antidepressant behaviour in mice carrying a gene-specific InsP3R1, InsP3R2 and InsP3R3 protein knockdown.	ITPR1 ITPR2	1.05e-05	2	113	2	18708078
Pubmed	Additional complexity on human chromosome 15q: identification of a set of newly recognized duplicons (LCR15) on 15q11-q13, 15q24, and 15q26.	GOLGA6B GOLGA6A	1.05e-05	2	113	2	11156619
Pubmed	Neocentromeres in 15q24-26 map to duplicons which flanked an ancestral centromere in 15q25.	GOLGA6B GOLGA6A	1.05e-05	2	113	2	12915487
Pubmed	Cdk1 protects against oxygen-glucose deprivation and reperfusion-induced Golgi fragmentation and apoptosis through mediating GM130 phosphorylation.	GOLGA6C GOLGA6B GOLGA6A	1.18e-05	14	113	3	37831422
Pubmed	Integrative characterization of germ cell-specific genes from mouse spermatocyte UniGene library.	RIMBP3 RIMBP3C RIMBP3B	1.18e-05	14	113	3	17662146
Pubmed	GM130 and p115 play a key role in the organisation of the early secretory pathway during skeletal muscle differentiation.	GOLGA6C GOLGA6B GOLGA6A	1.18e-05	14	113	3	30630895
Pubmed	Golgb1 regulates protein glycosylation and is crucial for mammalian palate development.	GOLGA6C GOLGA6B GOLGA6A	1.18e-05	14	113	3	27226319
Pubmed	Oligoasthenoteratospermia and sperm tail bending in PPP4C-deficient mice.	GOLGA6C GOLGA6B GOLGA6A	1.18e-05	14	113	3	33543287
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	XRN2 FXR2 TSPYL2 DDX56 CHD8 HUWE1 ITPR1 ITPR2 GTF3C1	1.43e-05	440	113	9	34244565
Pubmed	Golgi disruption and early embryonic lethality in mice lacking USO1.	GOLGA6C GOLGA6B GOLGA6A	1.48e-05	15	113	3	23185636
Pubmed	The a3 isoform of V-ATPase regulates insulin secretion from pancreatic beta-cells.	GOLGA6C GOLGA6B GOLGA6A	1.48e-05	15	113	3	17046993
Pubmed	Mouse oocytes within germ cell cysts and primordial follicles contain a Balbiani body.	GOLGA6C GOLGA6B GOLGA6A	1.48e-05	15	113	3	17189423
Pubmed	WDR38, a novel equatorial segment protein, interacts with the GTPase protein RAB19 and Golgi protein GM130 to play roles in acrosome biogenesis.	GOLGA6C GOLGA6B GOLGA6A	1.48e-05	15	113	3	37635409
Pubmed	Golga5 is dispensable for mouse embryonic development and postnatal survival.	GOLGA6C GOLGA6B GOLGA6A	1.48e-05	15	113	3	28509431
Pubmed	GM130 Regulates Golgi-Derived Spindle Assembly by Activating TPX2 and Capturing Microtubules.	GOLGA6C GOLGA6B GOLGA6A	1.48e-05	15	113	3	26165940
Pubmed	Calumin, a novel Ca2+-binding transmembrane protein on the endoplasmic reticulum.	GOLGA6C GOLGA6B GOLGA6A	1.48e-05	15	113	3	17204322
Pubmed	Demonstration of the expression and the enzymatic activity of N-acetylglucosaminyltransferase IX in the mouse brain.	GOLGA6C GOLGA6B GOLGA6A	1.48e-05	15	113	3	16413118
Pubmed	RhoA-mediated FMNL1 regulates GM130 for actin assembly and phosphorylates MAPK for spindle formation in mouse oocyte meiosis.	GOLGA6C GOLGA6B GOLGA6A	1.48e-05	15	113	3	26083584
Pubmed	LIM kinase 2 is widely expressed in all tissues.	GOLGA6C GOLGA6B GOLGA6A	1.81e-05	16	113	3	16399995
Pubmed	SLC24A5 encodes a trans-Golgi network protein with potassium-dependent sodium-calcium exchange activity that regulates human epidermal melanogenesis.	GOLGA6C GOLGA6B GOLGA6A	1.81e-05	16	113	3	18166528
Pubmed	Molecular motor KIF1C is not essential for mouse survival and motor-dependent retrograde Golgi apparatus-to-endoplasmic reticulum transport.	GOLGA6C GOLGA6B GOLGA6A	1.81e-05	16	113	3	11784862
Pubmed	p125/Sec23-interacting protein (Sec23ip) is required for spermiogenesis.	GOLGA6C GOLGA6B GOLGA6A	1.81e-05	16	113	3	21640725
Pubmed	Molecular characterization of mitocalcin, a novel mitochondrial Ca2+-binding protein with EF-hand and coiled-coil domains.	GOLGA6C GOLGA6B GOLGA6A	1.81e-05	16	113	3	16336229
Pubmed	Control of TurboID-dependent biotinylation intensity in proximity ligation screens.	PDCD6 DENND4C ITPR1 ITPR2 POFUT2	1.95e-05	100	113	5	36966971
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	XRN2 LUC7L3 UBL4A CHD8 HUWE1 AP3B1 SSUH2 XPO6 TUBGCP3 ARAP1	2.12e-05	582	113	10	20467437
Pubmed	Sox9 plays multiple roles in the lung epithelium during branching morphogenesis.	LAMA1 GOLGA6C GOLGA6B GOLGA6A	2.17e-05	50	113	4	24191021
Pubmed	Dynamics and function of CXCR4 in formation of the granule cell layer during hippocampal development.	GOLGA6C GOLGA6B GOLGA6A	2.20e-05	17	113	3	28717168
Pubmed	The Protein Tyrosine Phosphatase MEG2 Regulates the Transport and Signal Transduction of Tropomyosin Receptor Kinase A.	GOLGA6C GOLGA6B GOLGA6A	2.20e-05	17	113	3	27655914
Pubmed	Vesicle budding from endoplasmic reticulum is involved in calsequestrin routing to sarcoplasmic reticulum of skeletal muscles.	GOLGA6C GOLGA6B GOLGA6A	2.20e-05	17	113	3	14728599
Pubmed	Phospholipase D2 localizes to the plasma membrane and regulates angiotensin II receptor endocytosis.	GOLGA6C GOLGA6B GOLGA6A	2.20e-05	17	113	3	14718562
Pubmed	A truncating mutation of TRAPPC9 is associated with autosomal-recessive intellectual disability and postnatal microcephaly.	GOLGA6C GOLGA6B GOLGA6A	2.20e-05	17	113	3	20004763
Pubmed	p115 Interacts with the GLUT4 vesicle protein, IRAP, and plays a critical role in insulin-stimulated GLUT4 translocation.	GOLGA6C GOLGA6B GOLGA6A	2.63e-05	18	113	3	15800058
Pubmed	Altered GLUT4 trafficking in adipocytes in the absence of the GTPase Arfrp1.	GOLGA6C GOLGA6B GOLGA6A	2.63e-05	18	113	3	20230794
Pubmed	Yip1B isoform is localized at ER-Golgi intermediate and cis-Golgi compartments and is not required for maintenance of the Golgi structure in skeletal muscle.	GOLGA6C GOLGA6B GOLGA6A	2.63e-05	18	113	3	25208654
Pubmed	Notch inhibition by the ligand DELTA-LIKE 3 defines the mechanism of abnormal vertebral segmentation in spondylocostal dysostosis.	GOLGA6C GOLGA6B GOLGA6A	2.63e-05	18	113	3	21147753
Pubmed	N-cadherin sustains motility and polarity of future cortical interneurons during tangential migration.	GOLGA6C GOLGA6B GOLGA6A	2.63e-05	18	113	3	24227724
Pubmed	Flightless, secreted through a late endosome/lysosome pathway, binds LPS and dampens cytokine secretion.	GOLGA6C GOLGA6B GOLGA6A	2.63e-05	18	113	3	22718342
Pubmed	Expression, localization, and biochemical characterization of nicotinamide mononucleotide adenylyltransferase 2.	GOLGA6C GOLGA6B GOLGA6A	2.63e-05	18	113	3	20943658
Pubmed	Protein kinase LKB1 regulates polarized dendrite formation of adult hippocampal newborn neurons.	GOLGA6C GOLGA6B GOLGA6A	2.63e-05	18	113	3	24367100
Pubmed	Cell influx and contractile actomyosin force drive mammary bud growth and invagination.	GOLGA6C GOLGA6B GOLGA6A	3.12e-05	19	113	3	34042944
Pubmed	Presenilin 1 mediates the turnover of telencephalin in hippocampal neurons via an autophagic degradative pathway.	GOLGA6C GOLGA6B GOLGA6A	3.12e-05	19	113	3	15452145
Pubmed	Scrg1, a novel protein of the CNS is targeted to the large dense-core vesicles in neuronal cells.	GOLGA6C GOLGA6B GOLGA6A	3.12e-05	19	113	3	14622145
Pubmed	Deletion of IFT20 exclusively in the RPE ablates primary cilia and leads to retinal degeneration.	GOLGA6C GOLGA6B GOLGA6A	3.12e-05	19	113	3	38048369
Pubmed	Pilt is a coiled-coil domain-containing protein that localizes at the trans-Golgi complex and regulates its structure.	GOLGA6C GOLGA6B GOLGA6A	3.12e-05	19	113	3	22841714
Pubmed	SDF2L1 interacts with the ER-associated degradation machinery and retards the degradation of mutant proinsulin in pancreatic β-cells.	GOLGA6C GOLGA6B GOLGA6A	3.12e-05	19	113	3	23444373
Pubmed	Presenilin 1 and presenilin 2 have differential effects on the stability and maturation of nicastrin in Mammalian brain.	GOLGA6C GOLGA6B GOLGA6A	3.12e-05	19	113	3	12646573
Pubmed	CLASP2 safeguards hematopoietic stem cell properties during mouse and fish development.	GOLGA6C GOLGA6B GOLGA6A	3.12e-05	19	113	3	35705037
Pubmed	Divergent functions and distinct localization of the Notch ligands DLL1 and DLL3 in vivo.	GOLGA6C GOLGA6B GOLGA6A	3.12e-05	19	113	3	17664336
Pubmed	Spatial regulation of Raf kinase signaling by RKTG.	GOLGA6C GOLGA6B GOLGA6A	3.12e-05	19	113	3	17724343
Pubmed	Stage-dependent function of Wnt5a during male external genitalia development.	GOLGA6C GOLGA6B GOLGA6A	3.12e-05	19	113	3	34255394
Pubmed	Regulation of amino acid transporter ATA2 by ubiquitin ligase Nedd4-2.	GOLGA6C GOLGA6B GOLGA6A	3.12e-05	19	113	3	17003038
Pubmed	A new spectrin, beta IV, has a major truncated isoform that associates with promyelocytic leukemia protein nuclear bodies and the nuclear matrix.	SPTB SPTBN4	3.13e-05	3	113	2	11294830
Pubmed	Evidence that type I, II, and III inositol 1,4,5-trisphosphate receptors can occur as integral plasma membrane proteins.	ITPR1 ITPR2	3.13e-05	3	113	2	10874040
Pubmed	Abnormal distribution of inositol 1,4,5-trisphosphate receptors in human muscle can be related to altered calcium signals and gene expression in Duchenne dystrophy-derived cells.	ITPR1 ITPR2	3.13e-05	3	113	2	20395455
Pubmed	Inositol 1,4,5-trisphosphate receptors are autoantibody target antigens in patients with Sjögren's syndrome and other systemic rheumatic diseases.	ITPR1 ITPR2	3.13e-05	3	113	2	17437169
Pubmed	Autism-associated CHD8 deficiency impairs axon development and migration of cortical neurons.	CHD8 GFAP	3.13e-05	3	113	2	30574290
Pubmed	Decreased olfactory mucus secretion and nasal abnormality in mice lacking type 2 and type 3 IP3 receptors.	ITPR1 ITPR2	3.13e-05	3	113	2	18547250
Pubmed	Inositol 1,4,5-trisphosphate receptor gene variants are related to the risk of breast cancer in a Chinese population.	ITPR1 ITPR2	3.13e-05	3	113	2	36350267
Pubmed	Inositol 1,4,5-trisphosphate receptors are essential for fetal-maternal connection and embryo viability.	ITPR1 ITPR2	3.13e-05	3	113	2	32320395
Pubmed	The versatility and universality of calcium signalling.	ITPR1 ITPR2	3.13e-05	3	113	2	11413485
Pubmed	Using concatenated subunits to investigate the functional consequences of heterotetrameric inositol 1,4,5-trisphosphate receptors.	ITPR1 ITPR2	3.13e-05	3	113	2	26009177
Pubmed	Receptor-activated single channels in intact human platelets.	ITPR1 ITPR2	3.13e-05	3	113	2	1693919
Interaction	XAGE1A interactions	DCAF1 FRAS1 TSPYL2 CHD8 CELSR3	2.59e-06	41	108	5	int:XAGE1A
Interaction	TOP3B interactions	FRAS1 FXR2 PIEZO1 SIPA1L3 SPTB UBL4A DDX56 CC2D1A CHD8 HUWE1 REXO1 ITPR2 SCAP DST CELSR3 XPO6 HELZ2 TNK2 ZER1 RIC1 ARAP1 RAB11FIP3	9.13e-06	1470	108	22	int:TOP3B
Interaction	PRKACA interactions	RASGRF1 ARHGAP36 CC2D1A HUWE1 GFAP ITPR1 ITPR2 PTPN12 AKAP9 GYS1 FBXO32 ALDOA	2.22e-05	519	108	12	int:PRKACA
Cytoband	14q23-q24.2	RAD51B SPTB	1.80e-05	3	113	2	14q23-q24.2
Cytoband	3p26.1	SSUH2 ITPR1	3.90e-04	12	113	2	3p26.1
Cytoband	19q13.13	SIPA1L3 SPTBN4	6.17e-04	15	113	2	19q13.13
GeneFamily	Inositol 1,4,5-triphosphate receptors\|Protein phosphatase 1 regulatory subunits	ITPR1 ITPR2	4.55e-05	3	71	2	297
GeneFamily	EF-hand domain containing\|Spectrins	SPTB SPTBN4	3.15e-04	7	71	2	1113
Coexpression	GSE29949_MICROGLIA_VS_DC_BRAIN_UP	CHD8 HUWE1 SSUH2 GYS1 FAM169A TNK2 ALG13 RAB11FIP3	2.48e-06	199	113	8	M8399
Coexpression	GSE37563_WT_VS_CTLA4_KO_CD4_TCELL_D4_POST_IMMUNIZATION_DN	ELOA PIEZO1 DST TNK2 MAPK3 KIF18B ALG13	1.60e-05	185	113	7	M9014
ToppCell	normal_Lung-Fibroblasts-COL13A1+_matrix_FBs\|Fibroblasts / Location, Cell class and cell subclass	FRAS1 PHACTR2 LUC7L3 ADARB1 ITPR1 DST AKAP9	7.49e-07	198	113	7	e0e47cf65774191981840b22905b2094b95abe0f
ToppCell	Hippocampus-Macroglia-POLYDENDROCYTE-P5-P5_1-Sox4-POLYDENDROCYTE_(Neurogenesis.Sox4.Cdc20)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	RAD51B MYO1A STIL KCNRG PJVK KIF18B	1.06e-06	131	113	6	f9fb8d74ca720b81fd5910cc975510359a8ef751
ToppCell	368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_4\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	GPAM DDX56 CELSR3 ADAM33 GGACT HPS5	3.65e-06	162	113	6	ca30d9bf61f4133566fdc91c7996e130ea554d01
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Neuronal-Glial_immature-ENCC/glia_Progenitor\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ANKRD13B CHST9 XKR6 FAN1 CELSR3 FAM169A	6.68e-06	180	113	6	c72f15763ba707189e29c85db533557f01c7fdb1
ToppCell	facs-Brain_Non-Myeloid-Striatum_-18m-Neuronal-interneuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPTB CHST9 ADARB1 ADCY1 SSUH2 ITPR1	8.06e-06	186	113	6	a1ab273b01971d6a892912560d387685dd657179
ToppCell	facs-Brain_Non-Myeloid-Striatum_-18m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPTB CHST9 ADARB1 ADCY1 SSUH2 ITPR1	8.31e-06	187	113	6	ef3c85c01bc3da408ae288b6e3096ad888a12e63
ToppCell	human_hepatoblastoma-Tumor_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	FRAS1 XRN2 LUC7L3 ITPR2 AKAP9 FAM169A	9.66e-06	192	113	6	916fbec1c7ab7969bda711886ac88e877e30c280
ToppCell	human_hepatoblastoma\|World / Sample and Cell Type and Tumor Cluster (all cells)	FRAS1 XRN2 LUC7L3 ITPR2 AKAP9 FAM169A	9.95e-06	193	113	6	e6a688bc834f845ff64dae1be64f073eec5091a1
Disease	Anoxic Encephalopathy	ITPR1 ITPR2	1.25e-05	2	105	2	C0003132
Disease	Brain Hypoxia	ITPR1 ITPR2	1.25e-05	2	105	2	C1527348
Disease	Anoxia of brain	ITPR1 ITPR2	1.25e-05	2	105	2	C0995195
Disease	Hypoxic Brain Damage	ITPR1 ITPR2	1.25e-05	2	105	2	C1140716
Disease	spinocerebellar ataxia type 5 (implicated_via_orthology)	SPTB SPTBN4	7.49e-05	4	105	2	DOID:0050882 (implicated_via_orthology)
Disease	Hermansky-Pudlak syndrome (is_implicated_in)	AP3B1 HPS5	2.60e-04	7	105	2	DOID:3753 (is_implicated_in)
Disease	thioredoxin domain-containing protein 12 measurement	DCAF1 SCAP CELSR3	3.65e-04	39	105	3	EFO_0008298
Disease	Hermanski-Pudlak Syndrome	AP3B1 HPS5	5.54e-04	10	105	2	C0079504
Disease	Hermansky-Pudlak syndrome	AP3B1 HPS5	5.54e-04	10	105	2	cv:C0079504
Disease	Trigeminal Neuralgia	GFAP MAPK3	8.09e-04	12	105	2	C0040997
Disease	autosomal dominant cerebellar ataxia (implicated_via_orthology)	ITPR1 ITPR2	8.09e-04	12	105	2	DOID:1441 (implicated_via_orthology)
Disease	Secondary Trigeminal Neuralgia	GFAP MAPK3	8.09e-04	12	105	2	C0393787
Disease	Trigeminal Neuralgia, Idiopathic	GFAP MAPK3	8.09e-04	12	105	2	C0393786
Disease	survival time, breast carcinoma	RAD51B ZFHX3	9.54e-04	13	105	2	EFO_0000305, EFO_0000714
Disease	platelet storage pool deficiency (implicated_via_orthology)	AP3B1 HPS5	1.28e-03	15	105	2	DOID:2223 (implicated_via_orthology)
Disease	Astrocytosis	GFAP MAPK3	1.65e-03	17	105	2	C3887640
Disease	Gliosis	GFAP MAPK3	1.65e-03	17	105	2	C0017639
Disease	urate measurement, bone density	GABRP FRAS1 LUC7L3 SNX19 ITPR1 ITPR2 TG HELZ2	1.68e-03	619	105	8	EFO_0003923, EFO_0004531
Disease	Sclerocystic Ovaries	ADARB1 REXO1 SPTBN4 TMF1	1.78e-03	144	105	4	C1136382
Disease	Polycystic Ovary Syndrome	ADARB1 REXO1 SPTBN4 TMF1	1.78e-03	144	105	4	C0032460
Disease	heart failure, diabetes mellitus, stroke, atrial fibrillation, mortality, coronary artery disease, cancer	DNAH2 ZFHX3	2.29e-03	20	105	2	EFO_0000275, EFO_0000400, EFO_0000712, EFO_0001645, EFO_0003144, EFO_0004352, MONDO_0004992
Disease	Primary microcephaly	STIL TUBGCP3	2.77e-03	22	105	2	C0431350
Disease	obsolete_red blood cell distribution width	XRN2 MYO1A FXR2 PIEZO1 SPTB UBL4A XKR6 AP3B1 REXO1 DENND4C LYRM2 HELZ2	3.04e-03	1347	105	12	EFO_0005192

Protein segments in the cluster

Peptide	Gene	Start	Entry
QRRIYRLVLEALQAE	EXOC3L1	526	Q86VI1
LTDYITRLEALQRRL	AKAP9	3876	Q99996
TLYRIELLRRLREQV	CHD8	1886	Q9HCK8
LEIRALSLIYNRDFI	ALG13	301	Q9NP73
ARENLLYRQLNDIRI	CFAP77	171	Q6ZQR2
RRFYRQLLLTADDRV	ALDOA	56	P04075
VAVRANNYEIVRLLL	ASB15	386	Q8WXK1
SQYLERLRRFISQEL	ABHD17A	291	Q96GS6
RLLEVANYVDQLLRT	ADAM33	236	Q9BZ11
IRFIYRLALTEEQQL	BEST1	46	O76090
LYIFLENIDRLQSLR	FAM186B	746	Q8IYM0
QYFLRLRDDLNVTRL	TNK2	21	Q07912
RLLRSNREVQYIVLQ	AP3B1	341	O00203
TRLILQYLDSERRQI	RAD51B	306	O15315
IFTLEYSVQRVRQLR	ARHGAP36	256	Q6ZRI8
RYLQAALEVERQLFL	RIMBP3B	186	A6NNM3
RYLQAALEVERQLFL	RIMBP3C	186	A6NJZ7
NFRLQDYIDRIIVAI	RAB11FIP3	731	O75154
RQEELRVYLRTSNLD	RIC1	561	Q4ADV7
RLQYSLQRIQELERA	GOLGA6A	161	Q9NYA3
ILQFILSVRLDYRIS	ITPR2	976	Q14571
LTRLRRYEIAVNLDL	MEOX1	196	P50221
LVQLVLRYRDYQRVV	ANKRD13B	96	Q86YJ7
IYNIVRVRSLRILEN	OVOS1	601	Q6IE37
LFDRYDGLRRLVNLI	DCAF1	476	Q9Y4B6
VLSARLQIIRIYIRE	FRAS1	3516	Q86XX4
IFIRNRILEIVYASL	GRINA	301	Q7Z429
SYLQEVEQLRLERLQ	FXR2	366	P51116
VQQLVDLLCRLELYR	IRAK2	71	O43187
EILQFILNVRLDYRI	ITPR1	986	Q14643
YRNIIERLQDIVSAL	ITPR1	1606	Q14643
LFYLEEQRRLRLQQL	MYO1A	686	Q9UBC5
NLYISEVRNIRLRLE	DST	1066	Q03001
TLDQLLRQERYKRFI	ASB12	41	Q8WXK4
LERRREAFTNIVYLN	HPS5	996	Q9UPZ3
NTLERSYRLRLFLEQ	DDX56	266	Q9NY93
IVLQRLTDIFRRYDT	PDCD6	156	O75340
RYEVARLLNLTERQV	HOXA9	236	P31269
FFILRKQYLQRQERL	MUL1	256	Q969V5
LLDLSTRRLIRVIYN	LRRK2	2436	Q5S007
LRYLQSLLAEVERRI	LUC7L3	86	O95232
ALYQRTVLRVQLLED	GGACT	86	Q9BVM4
AIYRAALEELQRRLQ	TUBGCP3	791	Q96CW5
VELGLFRYRLRELQT	GDPGP1	71	Q6ZNW5
YCQRTLREIQILLRF	MAPK3	81	P27361
RLQREALFYELRSLV	KCNRG	81	Q8N5I3
LNLYRRSERQELAEL	KCNT2	1041	Q6UVM3
AELQARRILRFNEYV	PHACTR2	566	O75167
YQAELRELRLRLDQL	GFAP	116	P14136
TLELERRFRQQRYLS	NKX2-8	96	O15522
EIISRRSLLRFLYTQ	ADARB1	396	P78563
RLQYSLQRIQELERA	GOLGA6B	161	A6NDN3
LLAELREYNLEQQRR	HUWE1	3641	Q7Z6Z7
LTTVELYRRLEARQQ	KIF18B	131	Q86Y91
LLQFERLVVLDYIIR	PI4K2A	291	Q9BTU6
NRYISRLLEARQTEL	ADCY1	566	Q08828
YLRLQDAREQRLRVL	ELOA	656	Q14241
LETYISNLDRVRLIR	GALNT4	186	Q8N4A0
VIERNRVILARRLYL	AXDND1	411	Q5T1B0
IRREYAAQLERQLQF	CC2D1A	901	Q6P1N0
LYRRNLVESELQRLR	CC2D1A	936	Q6P1N0
RQRSLYREILFLSLV	DENND4C	1841	Q5VZ89
RLQYSLQRIQELERA	GOLGA6C	161	A6NDK9
GERVVLYVLNRIIYR	FAM169A	111	Q9Y6X4
FVRRQQVLLLYRRIL	LYRM2	16	Q9NU23
YSSREQLDLLLRRQL	CELSR3	3066	Q9NYQ7
RRYLDVVLQRQILLA	HELZ2	1676	Q9BYK8
VFLEALARLNYLLRV	GYS1	341	P13807
SRRFNYVVRLLELIA	FBXO32	116	Q969P5
LRENLLLVARDYNRI	DNAH2	671	Q9P225
VVYFLARTRLAQRLI	SCAP	506	Q12770
NLREEFTRYLFVLQL	EPB41L4B	171	Q9H329
ALRLQVSREQYLELV	NOA1	191	Q8NC60
RLVLQFELRRNVLYF	GABRP	231	O00591
ERFLRQRQVLLLFVF	PCDHB3	6	Q9Y5E6
YLRSLVQNLLLIRRF	MAP3K15	481	Q6ZN16
YTRILSRFVEILQRL	FAN1	666	Q9Y2M0
QLYQERLQRGEILLR	PTGFRN	81	Q9P2B2
VIRQRYLNLFIEECL	REXO1	816	Q8N1G1
FLEIYQRRRLRVVLE	NKPD1	221	Q17RQ9
FNLRRDVYIRIASLL	POFUT2	56	Q9Y2G5
RYLQAALEVERQLFL	RIMBP3	186	Q9UFD9
LEFTSARYIRLRLQR	LAMA1	216	P25391
ARRLSYVLFIQERDV	GPAM	106	Q9HCL2
RTLLLEFQNESRRLY	PTPN12	176	Q05209
QYRIIFRTRELITLR	SIPA1L3	546	O60292
LQIRYASVERLLERL	RASGRF1	646	Q13972
EIAFRVLRARLYQQI	MTRF1	346	O75570
LVIQELKRQTLCRYR	SSUH2	101	Q9Y2M2
QVLVLVERRRTLYIQ	ARAP1	921	Q96P48
RQYLKDLTRTERQLI	CHST9	411	Q7L1S5
DAYRFLTEQDRQLRL	STIL	721	Q15468
LRTQLRDLDQRYNTI	TMF1	1041	P82094
FVDRRLRRTINILQY	XKR6	601	Q5GH73
LEFQYRRVNELLLSI	ZER1	471	Q7Z7L7
DQPEIALRFYRRLLQ	TTC8	366	Q8TAM2
ISILINRRDEDIFRY	TSPYL2	276	Q9H2G4
TLLYIRQFILERNAI	ZNF826P	81	Q6ZT77
EQLQLLELVFRRTRY	MIXL1	96	Q9H2W2
TFALLYRLRNILFER	PJVK	241	Q0ZLH3
IIEELRQFQRLTRSY	SRPX2	401	O60687
FIFLRLNVLREYLER	XRN2	301	Q9H0D6
YQLFLRDLRQALVVL	SPTBN4	1201	Q9H254
SYLQELLQSRRQRLE	SPTB	511	P11277
RRYREFLNLQTRLEE	SNX19	581	Q92543
LEQLQRDYERSLSRL	UBL4A	116	P11441
LLRYNERLDRLFISE	ZSWIM3	81	Q96MP5
LLLLVFEAIVYRRQE	PIEZO1	936	Q92508
IQRREATLLDLRSYL	TRAPPC10	296	P48553
VLLLTEVLNRIQFRY	XPO6	451	Q96QU8
TYRLLKRRNLIIEAV	GTF3C1	611	Q12789
LYRILQRRFLAVQSV	TG	276	P01266
IFLLCYRERVLETQL	TMEM198	76	Q66K66
RITDDQLRVLRQYFD	ZFHX3	2151	Q15911
QSIRRFVLNIQLTYR	MYO5C	876	Q9NQX4
ILRSAIQYIERLQAL	MYOG	121	P15173