Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionintracellularly ligand-gated monoatomic ion channel activity

TRPA1 HCN4 HCN1 HCN3 HCN2 RYR1

1.98e-0933736GO:0005217
GeneOntologyMolecularFunctionintracellularly cAMP-activated cation channel activity

HCN4 HCN1 HCN3 HCN2

3.39e-0810734GO:0005222
GeneOntologyMolecularFunctionvoltage-gated monoatomic cation channel activity

CACNA1B CACNA1C TRPA1 HCN4 HCN1 HCN3 HCN2 RYR1

8.29e-08152738GO:0022843
GeneOntologyMolecularFunctionintracellularly cyclic nucleotide-activated monoatomic cation channel activity

HCN4 HCN1 HCN3 HCN2

1.15e-0713734GO:0005221
GeneOntologyMolecularFunctioncyclic nucleotide-activated monoatomic ion channel activity

HCN4 HCN1 HCN3 HCN2

1.15e-0713734GO:0043855
GeneOntologyMolecularFunctionvoltage-gated monoatomic ion channel activity

CACNA1B CACNA1C TRPA1 HCN4 HCN1 HCN3 HCN2 RYR1

3.31e-07182738GO:0005244
GeneOntologyMolecularFunctionvoltage-gated channel activity

CACNA1B CACNA1C TRPA1 HCN4 HCN1 HCN3 HCN2 RYR1

3.60e-07184738GO:0022832
GeneOntologyMolecularFunctioncAMP binding

HCN4 HCN1 HCN3 HCN2

1.96e-0625734GO:0030552
GeneOntologyMolecularFunctionvoltage-gated sodium channel activity

HCN4 HCN1 HCN3 HCN2

2.31e-0626734GO:0005248
GeneOntologyMolecularFunctioncyclic nucleotide binding

HCN4 HCN1 HCN3 HCN2

1.23e-0539734GO:0030551
GeneOntologyMolecularFunctionligand-gated monoatomic cation channel activity

TRPA1 HCN4 HCN1 HCN3 HCN2 RYR1

1.23e-05140736GO:0099094
GeneOntologyMolecularFunctionvoltage-gated calcium channel activity

CACNA1B CACNA1C TRPA1 RYR1

2.39e-0546734GO:0005245
GeneOntologyMolecularFunctiongated channel activity

CACNA1B CACNA1C TRPA1 HCN4 HCN1 HCN3 HCN2 RYR1

2.94e-05334738GO:0022836
GeneOntologyMolecularFunctionmonoatomic cation channel activity

CACNA1B CACNA1C TRPA1 HCN4 HCN1 HCN3 HCN2 RYR1

3.56e-05343738GO:0005261
GeneOntologyMolecularFunctionsodium channel activity

HCN4 HCN1 HCN3 HCN2

3.90e-0552734GO:0005272
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

CACNA1B CACNA1C TRPA1 HCN4 HCN1 HCN3 HCN2 RYR1 SLC5A4

4.83e-05465739GO:0046873
GeneOntologyMolecularFunctionligand-gated monoatomic ion channel activity

TRPA1 HCN4 HCN1 HCN3 HCN2 RYR1

7.50e-05193736GO:0015276
GeneOntologyMolecularFunctionG protein-coupled receptor activity

FZD3 GPR142 OR13A1 OR1A1 GPR141 OR6Y1 OR1A2 OR6C68 OR2A5 CCR7 OR5AR1 PTGFR

8.01e-058847312GO:0004930
GeneOntologyMolecularFunctionligand-gated channel activity

TRPA1 HCN4 HCN1 HCN3 HCN2 RYR1

8.40e-05197736GO:0022834
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

CACNA1B CACNA1C TRPA1 HCN4 HCN1 HCN3 HCN2 RYR1 ATP6V0A2 SLC5A4

9.07e-056277310GO:0022890
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

NPC1 TRPA1 FZD3 GPR142 OR13A1 OR1A1 GPR141 OR6Y1 OR1A2 CD79B OR6C68 OR2A5 CCR7 OR5AR1 PTGFR

9.38e-0513537315GO:0004888
GeneOntologyMolecularFunctionsterol binding

NPC1 GPR141 OSBPL10 STAR

1.33e-0471734GO:0032934
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

CACNA1B CACNA1C TRPA1 HCN4 HCN1 HCN3 HCN2 RYR1 ATP6V0A2 SLC5A4

1.45e-046647310GO:0008324
GeneOntologyMolecularFunctionmonoatomic ion channel activity

CACNA1B CACNA1C TRPA1 HCN4 HCN1 HCN3 HCN2 RYR1

2.67e-04459738GO:0005216
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

HCN4 HCN1 HCN3 HCN2 SLC5A4

4.08e-04171735GO:0015081
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

CACNA1B CACNA1C TRPA1 HCN4 HCN1 HCN3 HCN2 RYR1 ATP6V0A2 SLC5A4

4.19e-047587310GO:0015318
GeneOntologyMolecularFunctionvoltage-gated potassium channel activity

HCN4 HCN1 HCN3 HCN2

5.33e-04102734GO:0005249
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

CACNA1B CACNA1C TRPA1 HCN4 HCN1 HCN3 HCN2 RYR1 ATP6V0A2 SLC5A4

5.95e-047937310GO:0015075
GeneOntologyMolecularFunctionchannel activity

CACNA1B CACNA1C TRPA1 HCN4 HCN1 HCN3 HCN2 RYR1

6.50e-04525738GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

CACNA1B CACNA1C TRPA1 HCN4 HCN1 HCN3 HCN2 RYR1

6.58e-04526738GO:0022803
GeneOntologyMolecularFunctiontransporter activity

NPC1 CACNA1B CACNA1C TRPA1 HCN4 HCN1 HCN3 OSBPL10 HCN2 STAR RYR1 ATP6V0A2 SLC5A4

7.26e-0412897313GO:0005215
GeneOntologyMolecularFunctionolfactory receptor activity

OR13A1 OR1A1 OR6Y1 OR1A2 OR6C68 OR2A5 OR5AR1

9.94e-04431737GO:0004984
GeneOntologyMolecularFunctionhigh voltage-gated calcium channel activity

CACNA1B CACNA1C

1.17e-0314732GO:0008331
GeneOntologyMolecularFunctionpotassium channel activity

HCN4 HCN1 HCN3 HCN2

1.25e-03128734GO:0005267
GeneOntologyMolecularFunctioncholesterol binding

NPC1 OSBPL10 STAR

1.25e-0358733GO:0015485
GeneOntologyMolecularFunctioncalcium channel activity

CACNA1B CACNA1C TRPA1 RYR1

1.28e-03129734GO:0005262
GeneOntologyMolecularFunctionsteroid binding

NPC1 GPR141 OSBPL10 STAR

1.44e-03133734GO:0005496
GeneOntologyMolecularFunctionnatural killer cell lectin-like receptor binding

ULBP2 RAET1L

1.73e-0317732GO:0046703
GeneOntologyMolecularFunctionintracellularly gated calcium channel activity

TRPA1 RYR1

1.94e-0318732GO:0015278
GeneOntologyMolecularFunctioncalcium ion transmembrane transporter activity

CACNA1B CACNA1C TRPA1 RYR1

2.28e-03151734GO:0015085
GeneOntologyMolecularFunctionpotassium ion transmembrane transporter activity

HCN4 HCN1 HCN3 HCN2

3.28e-03167734GO:0015079
GeneOntologyMolecularFunctionvirus receptor activity

NPC1 CD80 ITGB3

3.74e-0385733GO:0001618
GeneOntologyMolecularFunctionexogenous protein binding

NPC1 CD80 ITGB3

3.86e-0386733GO:0140272
GeneOntologyMolecularFunctionligand-gated calcium channel activity

TRPA1 RYR1

5.72e-0331732GO:0099604
GeneOntologyMolecularFunctionalcohol binding

NPC1 OSBPL10 STAR

6.21e-03102733GO:0043178
GeneOntologyMolecularFunctionchemokine binding

CCR7 ITGB3

6.47e-0333732GO:0019956
GeneOntologyMolecularFunctionhormone receptor binding

JAK3 GNAS

6.86e-0334732GO:0051427
GeneOntologyBiologicalProcessresponse to organic cyclic compound

NPC1 CACNA1B CACNA1C TRPA1 HCN4 MTOR GLDC HCN1 HCN3 ULBP2 RAET1L TAF2 GNAS HCN2 PTGFR TOP2B RYR1

8.46e-0810487217GO:0014070
GeneOntologyBiologicalProcessresponse to nitrogen compound

NPC1 JAK3 CACNA1B HCN4 MTOR GLDC HCN1 HCN3 ULBP2 RAET1L CCR7 GNAS HCN2 RNF139 ITGB3 TOP2B RYR1

1.29e-0612727217GO:1901698
GeneOntologyBiologicalProcessregulation of membrane depolarization

CACNA1C HCN4 HCN1 HCN3 HCN2

2.30e-0661725GO:0003254
GeneOntologyBiologicalProcessT-helper 1 cell differentiation

JAK3 MTOR CD80 CCR7

3.03e-0629724GO:0045063
GeneOntologyBiologicalProcessresponse to organophosphorus

HCN4 HCN1 HCN3 HCN2 TOP2B RYR1

1.03e-05142726GO:0046683
GeneOntologyBiologicalProcesscellular response to nitrogen compound

JAK3 HCN4 MTOR HCN1 HCN3 ULBP2 RAET1L GNAS HCN2 ITGB3 TOP2B RYR1

1.04e-057527212GO:1901699
GeneOntologyBiologicalProcessregulation of T-helper 1 cell differentiation

JAK3 CD80 CCR7

1.44e-0514723GO:0045625
GeneOntologyBiologicalProcessresponse to purine-containing compound

HCN4 HCN1 HCN3 HCN2 TOP2B RYR1

2.50e-05166726GO:0014074
GeneOntologyBiologicalProcesscellular response to cAMP

HCN4 HCN1 HCN3 HCN2

3.51e-0553724GO:0071320
GeneOntologyBiologicalProcessmetal ion transport

JAK3 CACNA1B CACNA1C TRPA1 HCN4 HCN1 HCN3 CCR7 GNAS HCN2 ITGB3 RYR1 SLC5A4

3.74e-0510007213GO:0030001
GeneOntologyBiologicalProcessmonoatomic cation transport

JAK3 CACNA1B CACNA1C TRPA1 HCN4 HCN1 HCN3 CCR7 GNAS HCN2 ITGB3 RYR1 ATP6V0A2 SLC5A4

3.97e-0511577214GO:0006812
GeneOntologyBiologicalProcessinorganic ion transmembrane transport

CACNA1B CACNA1C TRPA1 HCN4 MTOR HCN1 HCN3 CCR7 HCN2 ITGB3 RYR1 ATP6V0A2 SLC5A4

4.45e-0510177213GO:0098660
GeneOntologyBiologicalProcesscellular response to organic cyclic compound

NPC1 HCN4 HCN1 HCN3 ULBP2 RAET1L GNAS HCN2 TOP2B RYR1

4.57e-056057210GO:0071407
GeneOntologyBiologicalProcessT-helper 1 type immune response

JAK3 MTOR CD80 CCR7

5.02e-0558724GO:0042088
GeneOntologyBiologicalProcessmembrane depolarization

CACNA1C HCN4 HCN1 HCN3 HCN2

6.54e-05121725GO:0051899
GeneOntologyBiologicalProcessmonoatomic ion transport

JAK3 CACNA1B CACNA1C TRPA1 HCN4 MTOR HCN1 HCN3 CCR7 GNAS HCN2 ITGB3 RYR1 ATP6V0A2 SLC5A4

6.56e-0513747215GO:0006811
GeneOntologyBiologicalProcessmembrane depolarization during cardiac muscle cell action potential

CACNA1C HCN4 HCN2

6.87e-0523723GO:0086012
GeneOntologyBiologicalProcessaction potential

CACNA1C TRPA1 HCN4 MTOR HCN1 HCN2

7.27e-05201726GO:0001508
GeneOntologyBiologicalProcessinorganic cation transmembrane transport

CACNA1B CACNA1C TRPA1 HCN4 HCN1 HCN3 CCR7 HCN2 ITGB3 RYR1 ATP6V0A2 SLC5A4

7.66e-059227212GO:0098662
GeneOntologyBiologicalProcessmonoatomic cation transmembrane transport

CACNA1B CACNA1C TRPA1 HCN4 HCN1 HCN3 CCR7 HCN2 ITGB3 RYR1 ATP6V0A2 SLC5A4

9.39e-059427212GO:0098655
GeneOntologyBiologicalProcesscalcium ion transmembrane import into cytosol

CACNA1B CACNA1C TRPA1 CCR7 ITGB3 RYR1

1.11e-04217726GO:0097553
GeneOntologyBiologicalProcessmonoatomic ion transmembrane transport

CACNA1B CACNA1C TRPA1 HCN4 MTOR HCN1 HCN3 CCR7 HCN2 ITGB3 RYR1 ATP6V0A2 SLC5A4

1.13e-0411157213GO:0034220
GeneOntologyBiologicalProcesssensory perception of chemical stimulus

TRPA1 OR13A1 OR1A1 OR6Y1 OR1A2 OR6C68 OR2A5 GNAS OR5AR1

1.17e-04547729GO:0007606
GeneOntologyBiologicalProcesscellular response to oxygen-containing compound

JAK3 TRPA1 HCN4 MTOR CD80 HCN1 HCN3 ULBP2 RAET1L GNAS HCN2 PTGFR ITGB3 TOP2B RYR1

1.20e-0414507215GO:1901701
GeneOntologyBiologicalProcessregulation of action potential

CACNA1C TRPA1 HCN4 HCN1

1.85e-0481724GO:0098900
GeneOntologyBiologicalProcesssensory perception of smell

OR13A1 OR1A1 OR6Y1 OR1A2 OR6C68 OR2A5 GNAS OR5AR1

2.13e-04465728GO:0007608
GeneOntologyBiologicalProcessnegative regulation of epithelial cell apoptotic process

NPC1 MTOR PKHD1 ITGB3

2.33e-0486724GO:1904036
GeneOntologyBiologicalProcessnegative regulation of macroautophagy

NPC1 MTOR CLEC16A

2.46e-0435723GO:0016242
GeneOntologyBiologicalProcessregulation of T-helper 1 type immune response

JAK3 CD80 CCR7

2.46e-0435723GO:0002825
GeneOntologyBiologicalProcesscellular response to cGMP

HCN4 HCN2

2.50e-047722GO:0071321
GeneOntologyBiologicalProcessresponse to prostaglandin

CCR7 GNAS PTGFR

2.68e-0436723GO:0034694
GeneOntologyBiologicalProcessmembrane depolarization during action potential

CACNA1C HCN4 HCN2

2.68e-0436723GO:0086010
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception

TRPA1 OR13A1 OR1A1 OR6Y1 OR1A2 OR6C68 OR2A5 OR5AR1

2.82e-04485728GO:0050907
GeneOntologyBiologicalProcessG protein-coupled receptor signaling pathway

FZD3 GPR142 OR13A1 OR1A1 GPR141 OR6Y1 OR1A2 OR6C68 OR2A5 CCR7 GNAS OR5AR1 PTGFR ITGB3

2.88e-0413957214GO:0007186
GeneOntologyBiologicalProcessT-helper cell differentiation

JAK3 MTOR CD80 CCR7

3.02e-0492724GO:0042093
GeneOntologyBiologicalProcessCD4-positive, alpha-beta T cell differentiation involved in immune response

JAK3 MTOR CD80 CCR7

3.28e-0494724GO:0002294
GeneOntologyBiologicalProcessregulation of cholangiocyte proliferation

MTOR PKHD1

3.32e-048722GO:1904054
GeneOntologyBiologicalProcessalpha-beta T cell differentiation involved in immune response

JAK3 MTOR CD80 CCR7

3.42e-0495724GO:0002293
GeneOntologyBiologicalProcessresponse to cAMP

HCN4 HCN1 HCN3 HCN2

3.70e-0497724GO:0051591
GeneOntologyBiologicalProcessalpha-beta T cell activation involved in immune response

JAK3 MTOR CD80 CCR7

3.85e-0498724GO:0002287
GeneOntologyBiologicalProcesssodium ion transport

HCN4 HCN1 HCN3 GNAS HCN2 SLC5A4

3.98e-04275726GO:0006814
GeneOntologyBiologicalProcesssusceptibility to natural killer cell mediated cytotoxicity

ULBP2 RAET1L

4.26e-049722GO:0042271
GeneOntologyBiologicalProcessresponse to cGMP

HCN4 HCN2

4.26e-049722GO:0070305
GeneOntologyBiologicalProcesspositive regulation of T-helper 1 cell differentiation

CD80 CCR7

4.26e-049722GO:0045627
GeneOntologyBiologicalProcessT cell differentiation involved in immune response

JAK3 MTOR CD80 CCR7

4.65e-04103724GO:0002292
GeneOntologyBiologicalProcessdetection of chemical stimulus

TRPA1 OR13A1 OR1A1 OR6Y1 OR1A2 OR6C68 OR2A5 OR5AR1

4.73e-04524728GO:0009593
GeneOntologyBiologicalProcesscholangiocyte proliferation

MTOR PKHD1

5.31e-0410722GO:1990705
GeneOntologyBiologicalProcessT cell costimulation

MTOR CD80 CCR7

7.53e-0451723GO:0031295
GeneOntologyBiologicalProcessresponse to pain

CACNA1B TRPA1 MTOR

7.53e-0451723GO:0048265
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception of smell

OR13A1 OR1A1 OR6Y1 OR1A2 OR6C68 OR2A5 OR5AR1

7.69e-04432727GO:0050911
GeneOntologyBiologicalProcessurinary bladder smooth muscle contraction

CACNA1C TRPA1

7.75e-0412722GO:0014832
GeneOntologyBiologicalProcessCD4-positive, alpha-beta T cell differentiation

JAK3 MTOR CD80 CCR7

8.01e-04119724GO:0043367
GeneOntologyBiologicalProcesssodium ion transmembrane transport

HCN4 HCN1 HCN3 HCN2 SLC5A4

8.04e-04208725GO:0035725
GeneOntologyBiologicalProcessregulation of actin filament-based process

CACNA1C HCN4 MTOR ASAP3 CCR7 ITGB3 CYFIP2

8.33e-04438727GO:0032970
GeneOntologyBiologicalProcesslymphocyte costimulation

MTOR CD80 CCR7

8.43e-0453723GO:0031294
GeneOntologyBiologicalProcessdetection of stimulus involved in sensory perception

TRPA1 OR13A1 OR1A1 OR6Y1 OR1A2 OR6C68 OR2A5 OR5AR1

9.38e-04582728GO:0050906
GeneOntologyBiologicalProcessmulticellular organismal response to stress

CACNA1B TRPA1 MTOR HCN1

9.91e-04126724GO:0033555
GeneOntologyBiologicalProcessregulation of T-helper cell differentiation

JAK3 CD80 CCR7

1.04e-0357723GO:0045622
GeneOntologyBiologicalProcessregulation of dendritic cell apoptotic process

JAK3 CCR7

1.06e-0314722GO:2000668
GeneOntologyBiologicalProcessdendritic cell apoptotic process

JAK3 CCR7

1.06e-0314722GO:0097048
GeneOntologyBiologicalProcessurinary tract smooth muscle contraction

CACNA1C TRPA1

1.23e-0315722GO:0014848
GeneOntologyBiologicalProcesspositive regulation of cell development

FZD3 MTOR CD80 RNF112 CCR7 GNAS ITGB3 STAR

1.32e-03614728GO:0010720
GeneOntologyBiologicalProcessregulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains

JAK3 CD80 ULBP2 RAET1L CCR7

1.38e-03235725GO:0002822
GeneOntologyBiologicalProcessneuronal action potential

TRPA1 MTOR HCN1

1.39e-0363723GO:0019228
GeneOntologyBiologicalProcessantigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent

ULBP2 RAET1L

1.40e-0316722GO:0002486
GeneOntologyCellularComponentHCN channel complex

HCN4 HCN1 HCN3 HCN2

1.37e-104734GO:0098855
GeneOntologyCellularComponentcation channel complex

CACNA1B CACNA1C HCN4 HCN1 HCN3 HCN2 RYR1

1.80e-05235737GO:0034703
GeneOntologyCellularComponentneuronal cell body

CACNA1B CACNA1C HCN4 FZD3 MTOR HCN1 RNF112 HCN3 GNAS HCN2 DMWD STAR

2.98e-058357312GO:0043025
GeneOntologyCellularComponentcell body

CACNA1B CACNA1C HCN4 FZD3 MTOR HCN1 RNF112 HCN3 GNAS HCN2 DMWD STAR

8.33e-059297312GO:0044297
GeneOntologyCellularComponentdendritic shaft

CACNA1B CACNA1C HCN1 HCN2

1.31e-0474734GO:0043198
GeneOntologyCellularComponentmembrane protein complex

CACNA1B CACNA1C COPG1 HCN4 HCN1 HCN3 CD79B GNAS EMC2 HCN2 ERN2 RNF139 ITGB3 RYR1 ATP6V0A2

1.75e-0414987315GO:0098796
GeneOntologyCellularComponentvoltage-gated potassium channel complex

HCN4 HCN1 HCN3 HCN2

2.91e-0491734GO:0008076
GeneOntologyCellularComponentmonoatomic ion channel complex

CACNA1B CACNA1C HCN4 HCN1 HCN3 HCN2 RYR1

3.50e-04378737GO:0034702
GeneOntologyCellularComponentplasma membrane protein complex

CACNA1B CACNA1C HCN4 HCN1 HCN3 CD79B GNAS HCN2 ITGB3 RYR1

3.85e-047857310GO:0098797
GeneOntologyCellularComponenttransmembrane transporter complex

CACNA1B CACNA1C HCN4 HCN1 HCN3 HCN2 RYR1 ATP6V0A2

4.70e-04523738GO:1902495
GeneOntologyCellularComponentpotassium channel complex

HCN4 HCN1 HCN3 HCN2

4.83e-04104734GO:0034705
GeneOntologyCellularComponentvoltage-gated calcium channel complex

CACNA1B CACNA1C RYR1

5.57e-0446733GO:0005891
GeneOntologyCellularComponenttransporter complex

CACNA1B CACNA1C HCN4 HCN1 HCN3 HCN2 RYR1 ATP6V0A2

6.54e-04550738GO:1990351
GeneOntologyCellularComponentdendrite

CACNA1B CACNA1C HCN4 FZD3 MTOR HCN1 HCN3 GNAS HCN2 DMWD

7.68e-048587310GO:0030425
GeneOntologyCellularComponentdendritic tree

CACNA1B CACNA1C HCN4 FZD3 MTOR HCN1 HCN3 GNAS HCN2 DMWD

7.82e-048607310GO:0097447
GeneOntologyCellularComponentside of membrane

JAK3 CD80 PKHD1 ULBP2 CD79B RAET1L CCR7 GNAS ITGB3 RYR1

8.93e-048757310GO:0098552
GeneOntologyCellularComponentendoplasmic reticulum protein-containing complex

EMC2 ERN2 RNF139 RYR1

9.64e-04125734GO:0140534
GeneOntologyCellularComponentextrinsic component of cytoplasmic side of plasma membrane

JAK3 GNAS RYR1

9.92e-0456733GO:0031234
GeneOntologyCellularComponentsomatodendritic compartment

CACNA1B CACNA1C HCN4 FZD3 MTOR HCN1 RNF112 HCN3 GNAS HCN2 DMWD STAR

1.05e-0312287312GO:0036477
GeneOntologyCellularComponentextrinsic component of membrane

JAK3 DUSP18 GNAS EMC2 RYR1

1.26e-03230735GO:0019898
GeneOntologyCellularComponentcell surface

CACNA1C FZD3 CD80 HCN1 TSPAN8 PKHD1 ULBP2 CD79B RAET1L CCR7 ITGB3

1.56e-0311117311GO:0009986
GeneOntologyCellularComponentcalcium channel complex

CACNA1B CACNA1C RYR1

2.13e-0373733GO:0034704
GeneOntologyCellularComponentexternal side of plasma membrane

CD80 PKHD1 ULBP2 CD79B RAET1L CCR7 ITGB3

2.21e-03519737GO:0009897
DomainIon_trans_N

HCN4 HCN1 HCN3 HCN2

1.92e-104714PF08412
DomainIon_trans_N

HCN4 HCN1 HCN3 HCN2

1.92e-104714IPR013621
DomainIon_trans_dom

CACNA1B CACNA1C TRPA1 HCN4 HCN1 HCN3 HCN2 RYR1

1.16e-08114718IPR005821
DomainIon_trans

CACNA1B CACNA1C TRPA1 HCN4 HCN1 HCN3 HCN2 RYR1

1.16e-08114718PF00520
DomainK_chnl_volt-dep_EAG/ELK/ERG

HCN4 HCN1 HCN3 HCN2

1.86e-0714714IPR003938
DomainCNMP_BINDING_1

HCN4 HCN1 HCN3 HCN2

6.36e-0632714PS00888
DomainCNMP_BINDING_2

HCN4 HCN1 HCN3 HCN2

6.36e-0632714PS00889
DomaincNMP

HCN4 HCN1 HCN3 HCN2

8.16e-0634714SM00100
DomaincNMP_binding

HCN4 HCN1 HCN3 HCN2

8.16e-0634714PF00027
DomaincNMP-bd_dom

HCN4 HCN1 HCN3 HCN2

9.18e-0635714IPR000595
DomainCNMP_BINDING_3

HCN4 HCN1 HCN3 HCN2

9.18e-0635714PS50042
DomaincNMP-bd-like

HCN4 HCN1 HCN3 HCN2

1.28e-0538714IPR018490
DomaincNMP-bd_CS

HCN4 HCN1 HCN2

2.85e-0516713IPR018488
Domain-

HCN4 HCN1 HCN3 HCN2

3.29e-05487142.60.120.10
DomainRmlC-like_jellyroll

HCN4 HCN1 HCN3 HCN2

4.19e-0551714IPR014710
DomainGPCR_Rhodpsn_7TM

GPR142 OR13A1 OR1A1 GPR141 OR6Y1 OR1A2 OR6C68 OR2A5 CCR7 OR5AR1 PTGFR

4.21e-056707111IPR017452
Domain7tm_1

GPR142 OR13A1 OR1A1 GPR141 OR6Y1 OR1A2 OR6C68 OR2A5 CCR7 OR5AR1 PTGFR

4.63e-056777111PF00001
DomainG_PROTEIN_RECEP_F1_1

GPR142 OR13A1 OR1A1 GPR141 OR6Y1 OR1A2 OR6C68 OR2A5 CCR7 OR5AR1 PTGFR

5.14e-056857111PS00237
DomainG_PROTEIN_RECEP_F1_2

GPR142 OR13A1 OR1A1 GPR141 OR6Y1 OR1A2 OR6C68 OR2A5 CCR7 OR5AR1 PTGFR

5.56e-056917111PS50262
DomainGPCR_Rhodpsn

GPR142 OR13A1 OR1A1 GPR141 OR6Y1 OR1A2 OR6C68 OR2A5 CCR7 OR5AR1 PTGFR

5.64e-056927111IPR000276
DomainPQQ

AASDH ERN2

2.12e-046712SM00564
DomainPQQ_beta_propeller_repeat

AASDH ERN2

2.12e-046712IPR018391
Domain-

AASDH ERN2

2.12e-0467122.140.10.10
DomainQuinoprotein_ADH-like_fam

AASDH ERN2

2.12e-046712IPR027295
DomainPQQ_repeat

AASDH ERN2

2.12e-046712IPR002372
DomainVDCC_a1su_IQ

CACNA1B CACNA1C

2.96e-047712IPR014873
DomainGPHH

CACNA1B CACNA1C

2.96e-047712PF16905
DomainGPHH_dom

CACNA1B CACNA1C

2.96e-047712IPR031649
DomainCa_chan_IQ

CACNA1B CACNA1C

2.96e-047712SM01062
DomainCa_chan_IQ

CACNA1B CACNA1C

2.96e-047712PF08763
DomainVDCCAlpha1

CACNA1B CACNA1C

6.29e-0410712IPR002077
DomainOlfact_rcpt

OR13A1 OR1A1 OR6Y1 OR1A2 OR6C68 OR2A5 OR5AR1

7.24e-04393717IPR000725
DomainMHC_I

ULBP2 RAET1L

2.86e-0321712PF00129
DomainMHC_I_a_a1/a2

ULBP2 RAET1L

2.86e-0321712IPR001039
Domain-

ULBP2 RAET1L

3.73e-03247123.30.500.10
DomainMHC_I-like_Ag-recog

ULBP2 RAET1L

3.73e-0324712IPR011161
PathwayKEGG_MEDICUS_REFERENCE_CA2_CAM_VGCC_RYR_SIGNALING_PATHWAY

CACNA1B CACNA1C RYR1

9.58e-0611563M47958
Pubmed

Functional expression of the human HCN3 channel.

HCN4 HCN1 HCN3 HCN2

1.79e-11473416043489
Pubmed

Interactive cloning with the SH3 domain of N-src identifies a new brain specific ion channel protein, with homology to eag and cyclic nucleotide-gated channels.

HCN4 HCN1 HCN3 HCN2

1.79e-1147349405696
Pubmed

Role of subunit heteromerization and N-linked glycosylation in the formation of functional hyperpolarization-activated cyclic nucleotide-gated channels.

HCN4 HCN1 HCN3 HCN2

1.79e-11473412928435
Pubmed

Hyperpolarization-activated and cyclic nucleotide-gated channels are differentially expressed in juxtaglomerular cells in the olfactory bulb of mice.

HCN4 HCN1 HCN3 HCN2

1.79e-11473420140458
Pubmed

Investigation of hyperpolarization-activated cyclic nucleotide-gated channels in interstitial cells of Cajal of human bladder.

HCN4 HCN1 HCN3 HCN2

1.79e-11473422748890
Pubmed

Identification of a gene encoding a hyperpolarization-activated pacemaker channel of brain.

HCN4 HCN1 HCN3 HCN2

1.79e-1147349630217
Pubmed

Genetic analysis of hyperpolarization-activated cyclic nucleotide-gated cation channels in sudden unexpected death in epilepsy cases.

HCN4 HCN1 HCN3 HCN2

1.79e-11473421615589
Pubmed

Pacsin 2 is required for the maintenance of a normal cardiac function in the developing mouse heart.

CACNA1C HCN4 HCN1 HCN3 HCN2

6.99e-111473529107716
Pubmed

Regulation of HCN channel surface expression by a novel C-terminal protein-protein interaction.

HCN4 HCN1 HCN3 HCN2

8.91e-11573415564593
Pubmed

Developmental HCN channelopathy results in decreased neural progenitor proliferation and microcephaly in mice.

HCN4 HCN1 HCN3 HCN2

8.91e-11573434429357
Pubmed

Transcription profiling of HCN-channel isotypes throughout mouse cardiac development.

HCN4 HCN1 HCN3 HCN2

6.22e-10773419421833
Pubmed

International Union of Pharmacology. LI. Nomenclature and structure-function relationships of cyclic nucleotide-regulated channels.

HCN4 HCN1 HCN3 HCN2

3.71e-091073416382102
Pubmed

Ventricular HCN channels decrease the repolarization reserve in the hypertrophic heart.

HCN4 HCN1 HCN2

8.87e-09373322652004
Pubmed

Cytoplasmic cAMP-sensing domain of hyperpolarization-activated cation (HCN) channels uses two structurally distinct mechanisms to regulate voltage gating.

HCN4 HCN1 HCN2

8.87e-09373321187420
Pubmed

Novel insights into the distribution of cardiac HCN channels: an expression study in the mouse heart.

HCN4 HCN1 HCN2

8.87e-09373321945247
Pubmed

Tetramerization dynamics of C-terminal domain underlies isoform-specific cAMP gating in hyperpolarization-activated cyclic nucleotide-gated channels.

HCN4 HCN1 HCN2

8.87e-09373322006928
Pubmed

HCN channels in the mammalian cochlea: Expression pattern, subcellular location, and age-dependent changes.

HCN4 HCN1 HCN2

8.87e-09373333181864
Pubmed

A family of hyperpolarization-activated mammalian cation channels.

HCN1 HCN3 HCN2

8.87e-0937339634236
Pubmed

Increased expression of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels in reactive astrocytes following ischemia.

HCN1 HCN3 HCN2

3.54e-08473325042871
Pubmed

Autism-associated SHANK3 haploinsufficiency causes Ih channelopathy in human neurons.

HCN1 HCN3 HCN2

3.54e-08473326966193
Pubmed

Functional coupling of Tmem74 and HCN1 channels regulates anxiety-like behavior in BLA neurons.

HCN1 HCN3 HCN2

8.84e-08573330886335
Pubmed

Differential expression of hyperpolarization-activated cyclic nucleotide-gated channel subunits during hippocampal development in the mouse.

HCN4 HCN1 HCN2

1.77e-07673325761792
Pubmed

Non-CpG methylation by DNMT3B facilitates REST binding and gene silencing in developing mouse hearts.

HCN4 HCN3 HCN2

3.09e-07773327956497
Pubmed

Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development.

CACNA1B CACNA1C HCN4 HCN1 HCN3 HCN2

4.99e-0713973616985003
Pubmed

Arrhythmia induced by spatiotemporal overexpression of calreticulin in the heart.

HCN4 HCN1 HCN2

1.93e-061273317482496
Pubmed

Hyperpolarization-activated cyclic nucleotide-gated channels in olfactory sensory neurons regulate axon extension and glomerular formation.

HCN4 HCN1 HCN2

3.96e-061573321147989
Pubmed

Compartmental distribution of hyperpolarization-activated cyclic-nucleotide-gated channel 2 and hyperpolarization-activated cyclic-nucleotide-gated channel 4 in thalamic reticular and thalamocortical relay neurons.

HCN4 HCN2

4.35e-06273216806719
Pubmed

Voltage-dependent opening of HCN channels: Facilitation or inhibition by the phytoestrogen, genistein, is determined by the activation status of the cyclic nucleotide gating ring.

HCN1 HCN2

4.35e-06273219524546
Pubmed

The Hyperpolarization-Activated HCN4 Channel is Important for Proper Maintenance of Oscillatory Activity in the Thalamocortical System.

HCN4 HCN2

4.35e-06273230877792
Pubmed

Hyperpolarization-activated cyclic nucleotide-modulated 'HCN' channels confer regular and faster rhythmicity to beating mouse embryonic stem cells.

HCN3 HCN2

4.35e-06273218033814
Pubmed

GST-Perfringolysin O production for the localization and quantification of membrane cholesterol in human and mouse brain and liver.

NPC1 STAR

4.35e-06273235024626
Pubmed

HCN channelopathy in external globus pallidus neurons in models of Parkinson's disease.

HCN1 HCN2

4.35e-06273221076425
Pubmed

Acid ceramidase improves mitochondrial function and oxidative stress in Niemann-Pick type C disease by repressing STARD1 expression and mitochondrial cholesterol accumulation.

NPC1 STAR

4.35e-06273234175669
Pubmed

Voltage sensor movement and cAMP binding allosterically regulate an inherently voltage-independent closed-open transition in HCN channels.

HCN1 HCN2

4.35e-06273217261842
Pubmed

Peripheral N- and C-terminal domains determine deactivation kinetics of HCN channels.

HCN4 HCN1

4.35e-06273217548059
Pubmed

Functional comparison of HCN isoforms expressed in ventricular and HEK 293 cells.

HCN4 HCN2

4.35e-06273212194012
Pubmed

An arginine residue in the pore region is a key determinant of chloride dependence in cardiac pacemaker channels.

HCN1 HCN2

4.35e-06273215644313
Pubmed

A leucine zipper motif essential for gating of hyperpolarization-activated channels.

HCN1 HCN2

4.35e-06273223048023
Pubmed

HCN2 and HCN1 channels govern the regularity of autonomous pacemaking and synaptic resetting in globus pallidus neurons.

HCN1 HCN2

4.35e-06273215525777
Pubmed

HCN1 and HCN2 proteins are expressed in cochlear hair cells: HCN1 can form a ternary complex with protocadherin 15 CD3 and F-actin-binding filamin A or can interact with HCN2.

HCN1 HCN2

4.35e-06273222948144
Pubmed

HCN3 contributes to the ventricular action potential waveform in the murine heart.

HCN1 HCN3

4.35e-06273221903939
Pubmed

Minimal molecular determinants of isoform-specific differences in efficacy in the HCN channel family.

HCN1 HCN2

4.35e-06273229980633
Pubmed

Processing of retinal signals in normal and HCN deficient mice.

HCN1 HCN2

4.35e-06273222279546
Pubmed

Molecular basis of the effect of potassium on heterologously expressed pacemaker (HCN) channels.

HCN1 HCN2

4.35e-06273212562911
Pubmed

Structural determinants of odorant recognition by the human olfactory receptors OR1A1 and OR1A2.

OR1A1 OR1A2

4.35e-06273217601748
Pubmed

Mechanotransduction and hyperpolarization-activated currents contribute to spontaneous activity in mouse vestibular ganglion neurons.

HCN1 HCN2

4.35e-06273224638995
Pubmed

Proteolytic processing of HCN2 and co-assembly with HCN4 in the generation of cardiac pacemaker channels.

HCN4 HCN2

4.35e-06273219574228
Pubmed

Evolutionary emergence of N-glycosylation as a variable promoter of HCN channel surface expression.

HCN1 HCN2

4.35e-06273220130205
Pubmed

Altered mTOR signaling and enhanced CYFIP2 expression levels in subjects with fragile X syndrome.

MTOR CYFIP2

4.35e-06273222268788
Pubmed

HCN2 and HCN4 isoforms self-assemble and co-assemble with equal preference to form functional pacemaker channels.

HCN4 HCN2

4.35e-06273217553794
Pubmed

Molecular basis for the different activation kinetics of the pacemaker channels HCN2 and HCN4.

HCN4 HCN2

4.35e-06273212813043
Pubmed

Two pacemaker channels from human heart with profoundly different activation kinetics.

HCN4 HCN2

4.35e-06273210228147
Pubmed

Different roles for the cyclic nucleotide binding domain and amino terminus in assembly and expression of hyperpolarization-activated, cyclic nucleotide-gated channels.

HCN1 HCN2

4.35e-06273212034718
Pubmed

In vitro characterization of HCN channel kinetics and frequency dependence in myocytes predicts biological pacemaker functionality.

HCN1 HCN2

4.35e-06273219171659
Pubmed

Intracellular Mg2+ is a voltage-dependent pore blocker of HCN channels.

HCN1 HCN2

4.35e-06273218579800
Pubmed

Mode shifts in the voltage gating of the mouse and human HCN2 and HCN4 channels.

HCN4 HCN2

4.35e-06273216777944
Pubmed

Hyperpolarization-activated cation current contributes to spontaneous network activity in developing neocortical cultures.

HCN1 HCN2

4.35e-06273222094222
Pubmed

Jak3 is involved in dendritic cell maturation and CCR7-dependent migration.

JAK3 CCR7

4.35e-06273219759904
Pubmed

Colocalization of hyperpolarization-activated, cyclic nucleotide-gated channel subunits in rat retinal ganglion cells.

HCN4 HCN1

4.35e-06273221456027
Pubmed

Hyperpolarization-activated channels HCN1 and HCN4 mediate responses to sour stimuli.

HCN4 HCN1

4.35e-06273211675786
Pubmed

Mutation analysis of the hyperpolarization-activated cyclic nucleotide-gated channels HCN1 and HCN2 in idiopathic generalized epilepsy.

HCN1 HCN2

4.35e-06273217931874
Pubmed

Enhanced expression of a specific hyperpolarization-activated cyclic nucleotide-gated cation channel (HCN) in surviving dentate gyrus granule cells of human and experimental epileptic hippocampus.

HCN1 HCN2

4.35e-06273212890777
Pubmed

Inhibition of wild-type p53-induced phosphatase 1 promotes liver regeneration in mice by direct activation of mammalian target of rapamycin.

MTOR PPM1D

4.35e-06273225704606
Pubmed

Case-control pharmacogenetic study of HCN1/HCN2 variants and genetic generalized epilepsies.

HCN1 HCN2

4.35e-06273229047147
Pubmed

Distinct RGK GTPases differentially use α1- and auxiliary β-binding-dependent mechanisms to inhibit CaV1.2/CaV2.2 channels.

CACNA1B CACNA1C

4.35e-06273222590648
Pubmed

Functional expression of the hyperpolarization-activated, non-selective cation current I(f) in immortalized HL-1 cardiomyocytes.

HCN1 HCN2

4.35e-06273212433951
Pubmed

HCN3 ion channels: roles in sensory neuronal excitability and pain.

HCN3 HCN2

4.35e-06273231290157
Pubmed

Functional heteromerization of HCN1 and HCN2 pacemaker channels.

HCN1 HCN2

4.35e-06273211133998
Pubmed

Ryanodine receptor activation by Ca v 1.2 is involved in dendritic cell major histocompatibility complex class II surface expression.

CACNA1C RYR1

4.35e-06273218927079
Pubmed

Downregulation of hyperpolarization-activated cyclic nucleotide-gated channels (HCN) in the hippocampus of patients with medial temporal lobe epilepsy and hippocampal sclerosis (MTLE-HS).

HCN1 HCN2

4.35e-06273232543742
Pubmed

MinK-related peptide 1: A beta subunit for the HCN ion channel subunit family enhances expression and speeds activation.

HCN1 HCN2

4.35e-06273211420311
Pubmed

Molecular composition and functional properties of f-channels in murine embryonic stem cell-derived pacemaker cells.

HCN4 HCN1

4.35e-06273219135060
Pubmed

Single-channel properties support a potential contribution of hyperpolarization-activated cyclic nucleotide-gated channels and If to cardiac arrhythmias.

HCN4 HCN2

4.35e-06273215687126
Pubmed

Control of heart rate by cAMP sensitivity of HCN channels.

HCN4 HCN2

4.35e-06273219570998
Pubmed

Olfactory receptor 43 reduces hepatic lipid accumulation and adiposity in mice.

OR1A1 OR1A2

4.35e-06273230639733
Pubmed

Different evolutionary processes shaped the mouse and human olfactory receptor gene families.

OR13A1 OR1A1 OR6Y1 OR1A2 OR6C68 OR2A5 OR5AR1

7.52e-0634073711875048
Pubmed

The olfactory receptor gene superfamily of the mouse.

OR13A1 OR1A1 OR6Y1 OR1A2 OR6C68 OR2A5 OR5AR1

7.52e-0634073711802173
Pubmed

A unified nomenclature for vertebrate olfactory receptors.

OR13A1 OR1A1 OR6Y1 OR1A2 OR6C68 OR2A5 OR5AR1

7.96e-0634373732295537
Pubmed

Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.

OR13A1 OR1A1 OR6Y1 OR1A2 OR6C68 OR2A5 OR5AR1

8.42e-0634673714611657
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

CACNA1C CDK13 ZNF330 PKHD1 CCAR1 MYH15 EMC2 DMWD OR5AR1 PTGFR TOP2B CYFIP2 CFAP46

8.60e-061442731335575683
Pubmed

Cyclic-Nucleotide- and HCN-Channel-Mediated Phototransduction in Intrinsically Photosensitive Retinal Ganglion Cells.

HCN4 HCN1 HCN2

1.15e-052173330270038
Pubmed

Maturation and cytokine production potential of dendritic cells isolated from rheumatoid arthritis patients peripheral blood and induced in vitro.

CD80 CCR7

1.30e-05373227421624
Pubmed

KCNE2 modulates current amplitudes and activation kinetics of HCN4: influence of KCNE family members on HCN4 currents.

HCN4 HCN2

1.30e-05373212856183
Pubmed

HCN channels expressed in the inner ear are necessary for normal balance function.

HCN1 HCN2

1.30e-05373222090507
Pubmed

A novel mechanism of modulation of hyperpolarization-activated cyclic nucleotide-gated channels by Src kinase.

HCN4 HCN2

1.30e-05373216079136
Pubmed

Triad proteins and intracellular Ca2+ transients during development of human skeletal muscle cells in aneural and innervated cultures.

CACNA1C RYR1

1.30e-05373211206130
Pubmed

Impaired dendritic expression and plasticity of h-channels in the fmr1(-/y) mouse model of fragile X syndrome.

HCN1 HCN2

1.30e-05373222662315
Pubmed

Molecular Basis of Regulating High Voltage-Activated Calcium Channels by S-Nitrosylation.

CACNA1B CACNA1C

1.30e-05373226507659
Pubmed

Mammalian target of rapamycin (mTOR) is involved in the survival of cells mediated by chemokine receptor 7 through PI3K/Akt in metastatic squamous cell carcinoma of the head and neck.

MTOR CCR7

1.30e-05373219615795
Pubmed

Targeted deletion of Kcne2 impairs HCN channel function in mouse thalamocortical circuits.

HCN1 HCN2

1.30e-05373222880098
Pubmed

The in vivo regulation of heart rate in the murine sinoatrial node by stimulatory and inhibitory heterotrimeric G proteins.

HCN4 GNAS

1.30e-05373223697798
Pubmed

Distinct localization and modulation of Cav1.2 and Cav1.3 L-type Ca2+ channels in mouse sinoatrial node.

CACNA1C HCN4

1.30e-05373223045342
Pubmed

Human anaplastic thyroid carcinoma cells are sensitive to NK cell-mediated lysis via ULBP2/5/6 and chemoattract NK cells.

ULBP2 RAET1L

1.30e-05373225212604
Pubmed

EP3 activation facilitates bladder excitability via HCN channels on ICCs.

HCN4 HCN1

1.30e-05373228131828
Pubmed

Interaction of the pacemaker channel HCN1 with filamin A.

HCN1 HCN2

1.30e-05373215292205
Pubmed

Taking the next step forward - Diagnosing inherited infantile cholestatic disorders with next generation sequencing.

NPC1 PKHD1

1.30e-05373225771912
Pubmed

Transcriptional control of pacemaker channel genes HCN2 and HCN4 by Sp1 and implications in re-expression of these genes in hypertrophied myocytes.

HCN4 HCN2

1.30e-05373219471099
Pubmed

Direct interaction of the mouse cytomegalovirus m152/gp40 immunoevasin with RAE-1 isoforms.

ULBP2 RAET1L

2.60e-05473220166740
Pubmed

PDK1-AKT signaling pathway regulates the expression and function of cardiac hyperpolarization-activated cyclic nucleotide-modulated channels.

HCN4 HCN2

2.60e-05473232184125
Pubmed

Whole-genome association study of bipolar disorder.

CACNA1C TSPAN8

2.60e-05473218317468
InteractionHCN4 interactions

HCN4 HCN1 HCN3 HCN2

1.66e-089704int:HCN4
InteractionPEX5L interactions

HCN4 HCN1 HCN3 HCN2 CYFIP2

1.21e-0654705int:PEX5L
InteractionKCNE2 interactions

CACNA1C HCN4 HCN2

2.22e-068703int:KCNE2
InteractionHCN3 interactions

HCN4 HCN1 HCN3

6.49e-0611703int:HCN3
InteractionHCN2 interactions

HCN4 HCN1 HCN2

1.12e-0513703int:HCN2
InteractionKEAP1 interactions

COPG1 CDK13 MAZ OSBPL10 HUWE1 ERN2 CLEC16A ATP6V0A2

1.94e-05332708int:KEAP1
GeneFamilyCyclic nucleotide gated channels

HCN4 HCN1 HCN3 HCN2

1.26e-0810524250
ToppCellPBMC-Control-Lymphocyte-B-B_cell-B_memory-B_memory-6|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SCRT2 CACNA1B CD80 OSBPL10 CD79B

4.67e-061497352cd860b96ed4be4d26844085d464961c1418054a
ToppCellAdult-Immune-B_cell-D231|Adult / Lineage, Cell type, age group and donor

JAK3 OR13A1 OSBPL10 CD79B CCR7

7.22e-061637354f5821299b265663c7d0352b28285f56e1988841
ToppCellfacs-Lung-EPCAM-3m-Endothelial-vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAZ OSBPL10 AASDH ITGB3 TMEM86A

7.44e-061647351d0d88132baaa3154c3e6e4ef0aff795afab08a2
ToppCellfacs-Lung-EPCAM-3m-Endothelial-Vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAZ OSBPL10 AASDH ITGB3 TMEM86A

7.44e-06164735bd2e10b015d5e6a338675500ec5d81dc39583b3e
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

CMIP HCN1 PKHD1 MYH15 KDM7A

1.37e-0518673523b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCellTracheal-NucSeq-Immune_Lymphocytic-B-B_cell|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

JAK3 CD80 CD79B CCR7 CYFIP2

1.85e-05198735824461cf44098440ba8bc0df96735423ac65bda1
ToppCellLPS-antiTNF-Myeloid-Dendritic_cells-Monocytes-Macrophages|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TRPA1 CD80 GPR141 TMEM86A

5.84e-05128734cfc73cb803ba50a4a8709e19e70e1e399118c849
ToppCell3'_v3-GI_small-bowel-Lymphocytic_T_CD4-Tregs|GI_small-bowel / Manually curated celltypes from each tissue

CD80 PKHD1 CCR7 RYR1

1.23e-04155734d4ef25965a15eab7679478b9b661e1b4a92f1c59
ToppCellfacs-Trachea-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l1|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KLHL29 HCN4 ZNF280C ASAP3

1.29e-041577341f21d78a467fe22c5ab75d0917b840c1ac93f32c
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1B HCN1 PKHD1 MYH15

1.39e-04160734c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell368C-Myeloid-Dendritic-cDC_activated|368C / Donor, Lineage, Cell class and subclass (all cells)

ODF4 CD80 GPR141 CCR7

1.39e-04160734bcd90ef96464bd901b87b94c696de70c113bfd03
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1B HCN1 PKHD1 MYH15

1.39e-0416073425c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellmild_COVID-19_(asymptomatic)-B_intermediate|World / disease group, cell group and cell class (v2)

CD80 OSBPL10 MYH15 CD79B

1.39e-041607346722934e153b72039c3c4308557d0ef879a30638
ToppCell10x5'-bone_marrow-Lymphocytic_B-ABC_aged-B_memory|bone_marrow / Manually curated celltypes from each tissue

CD80 OR13A1 OSBPL10 CD79B

1.52e-04164734746833f74095c0f25ce76baf1069f1848c231933
ToppCellfacs-Trachea-3m-Hematologic-myeloid-tracheal_macrophage-macrophage_of_tracheal_l15|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CD80 GPR141 CCR7 RYR1

1.52e-041647345ca7b69684a8bb12dd0b45e7ad94e30d16ed01ce
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_5|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CD80 GPR141 CCR7 SLC5A4

1.52e-041647343a4ecc632be003d09b765c992804134348d2278b
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_5|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CD80 GPR141 CCR7 SLC5A4

1.52e-041647344b10b78d4d76023c3c5bcd427757218fdd5465ca
ToppCell343B-Myeloid-Macrophage-FABP4+_Macrophage_proliferating_2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

NICN1 HCN3 ASAP3 ITGB3

1.60e-04166734f4698fd08965936d51695d571bd10fb77330d916
ToppCellControl-B_cells-Activated_B_cells|Control / group, cell type (main and fine annotations)

OSBPL10 CD79B CCR7 CYFIP2

1.67e-04168734a7159a35fe37f8c241cf8d391debe271e0698105
ToppCell3'_v3-GI_small-bowel-Lymphocytic_B-Memory_B_cells|GI_small-bowel / Manually curated celltypes from each tissue

CD80 OSBPL10 CD79B CCR7

1.67e-041687348e025bb0541746e232b77ac0e31412ae71420c47
ToppCell3'_v3-GI_small-bowel-Lymphocytic_B|GI_small-bowel / Manually curated celltypes from each tissue

CD80 OSBPL10 CD79B CCR7

1.67e-041687345535c1b8b7fde7b59a1bc0580cebdfa963aa1c39
ToppCellURO-Lymphocyte-B-B_intermediate|URO / Disease, Lineage and Cell Type

GLDC OSBPL10 CD79B CCR7

1.75e-04170734e11d1510518cedabeece96d4adbb90999e6326fa
ToppCelldroplet-Thymus-nan-21m-Myeloid-B_cell|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD80 OSBPL10 CD79B RYR1

1.79e-041717348bed33f61f7d12a1ac4fba33f730d839f5ee7bef
ToppCellCOVID-19-kidney-Bcells|COVID-19 / Disease (COVID-19 only), tissue and cell type

OR13A1 OSBPL10 CD79B CCR7

1.79e-041717348e8fb79968b1a5c34d1d9cad7f9155fabfdb7cc7
ToppCellfacs-Lung-Endomucin_-18m-Myeloid-non-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD80 GPR141 TRMT1 CYFIP2

1.87e-04173734c31076c725f4cd912c56903592a2d9356ae59f54
ToppCellfacs-Diaphragm-Limb_Muscle-18m-Lymphocytic-B_cell|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD80 GPR141 CD79B CCR7

1.87e-04173734a693772987f1baee533dd0bd285a3c7b5619a73b
ToppCellfacs-Lung-Endomucin_-18m-Myeloid-Nonclassical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD80 GPR141 TRMT1 CYFIP2

1.87e-04173734a4ed191cfdf6588b7f3672995bf0a4fe9e4b8df6
ToppCellmild_COVID-19_(asymptomatic)-B_memory|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)

CD80 OSBPL10 CD79B CCR7

1.87e-041737349082ad77b44f65b72094df6e502cce81b62fe81a
ToppCelldroplet-Kidney-KIDNEY-30m-Lymphocytic-B_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD80 CD79B CCR7 RYR1

1.95e-04175734738b3d476ac494e2e79b70b3b83bc1b7ae8396bd
ToppCellfacs-Marrow-B-cells-24m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PKHD1 MYH15 CD79B CCR7

1.95e-04175734887e75fc90e59a6394d62f3c048a9cfdf6707725
ToppCellCOVID-19-lung-B_cells|lung / Disease (COVID-19 only), tissue and cell type

OSBPL10 CD79B CCR7 CYFIP2

2.04e-04177734f54691e5558091c1734ab15153a10bff15ed171e
ToppCellmild_COVID-19_(asymptomatic)-B_memory|World / disease group, cell group and cell class (v2)

CD80 OSBPL10 CD79B CCR7

2.04e-04177734057871e211c6508b2a679d391f3cf0ac7ccfc628
ToppCelldroplet-Kidney-KIDNEY-30m-Lymphocytic-CD45____B_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD80 CD79B CCR7 RYR1

2.08e-041787345a4f97d19265577cfdb3e53f9dc3a9a02cfcffa9
ToppCell343B-Lymphocytic-CD4_T-cell-Treg_cell_4|343B / Donor, Lineage, Cell class and subclass (all cells)

CD80 NICN1 CD79B RYR1

2.13e-04179734c09c3eed43d1aa3b7aa8f3021e6f2737840cde16
ToppCelldroplet-Lung-nan|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPAN8 CD79B CCR7 GNAS

2.13e-04179734006f2b6887b0f1f26e58bb11c919468b62bf4d62
ToppCellIPF-Lymphoid-B|World / Disease state, Lineage and Cell class

OSBPL10 CD79B CCR7 CYFIP2

2.17e-0418073430f9398c9b784f49470847a025bac90687e997a1
ToppCellsevere-CD8+_T_naive|World / disease stage, cell group and cell class

FZD3 OSBPL10 CCR7 EFR3A

2.22e-0418173469eeeb7f326e230b07495d557f708fbe3312ac0a
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KLHL29 PKHD1 OSBPL10 PTGFR

2.22e-041817349d782ba5cf5a172cb4f447763fc50e5b13ef7dd9
ToppCellControl-Lymphoid-B|World / Disease state, Lineage and Cell class

OSBPL10 CD79B CCR7 CYFIP2

2.22e-041817349124f1a610cfc3355ad87921cd3eb5346956475d
ToppCellnucseq-Immune-Lymphocytic_B-Lymphocytic_B-B|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

OSBPL10 CD79B CCR7 CYFIP2

2.22e-041817348d8cc4dae2c8bd5f4b1c159f2a52edc4c9449c86
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KLHL29 PKHD1 OSBPL10 PTGFR

2.27e-04182734eb138aa1dca9373f1586600f258df06dcf56d81f
ToppCellIPF-Lymphoid-B|IPF / Disease state, Lineage and Cell class

OSBPL10 CD79B CCR7 CYFIP2

2.32e-04183734e37d2c015c34471a8a54a0299e94b0371e1ada5a
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_B-B_plasma-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

GLDC CD80 MYH15 TMEM86A

2.32e-04183734dd15e1463a0d57d14800de0df0645c81c56926ae
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_B-B_plasma|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

GLDC CD80 MYH15 TMEM86A

2.32e-041837348ace19c38b89556d2504258a63aa5a2b14f5cd36
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KLHL29 PKHD1 OSBPL10 PTGFR

2.32e-0418373492fbd83a9d13ee91065cbd479fb298f1fd564568
ToppCellControl-Lymphoid-B|Control / Disease state, Lineage and Cell class

OSBPL10 CD79B CCR7 CYFIP2

2.36e-04184734de0294f879268bfd68e91adcc2adba211d221b7a
ToppCellCOVID-19-lung-B_cells|COVID-19 / Disease (COVID-19 only), tissue and cell type

OSBPL10 CD79B CCR7 CYFIP2

2.41e-04185734e8f1ad580f19705b5ca1d7d8867b2125f4891684
ToppCellControl-Myeloid-DC_Mature|Myeloid / Disease state, Lineage and Cell class

CD80 GPR141 CCR7 ATP6V0A2

2.46e-04186734e9e58c5871b4966cd3586b611703e21af8df6360
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Macroglial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DUSP18 FZD3 HCN1 HCN3

2.51e-0418773416e55d802fc4e71878305e61ad03806aabd59537
ToppCellControl-Myeloid-DC_Mature|Control / Disease state, Lineage and Cell class

CD80 GPR141 CCR7 ATP6V0A2

2.51e-04187734049780ca2a3e6adcd89dc2cf3095b5ad068b244a
ToppCell10x5'v1-week_17-19-Lymphocytic_T-T_NK-NK_T_cell|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

JAK3 FZD3 CCR7 LRP2BP

2.51e-041877343301e0fca8c436d136c71f1a8fd59b3bb11bdd83
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KLHL29 PKHD1 OSBPL10 PTGFR

2.51e-04187734c41a2c81dd2ceef303f39f699032aa7d6ea67cf0
ToppCellControl-Myeloid-DC_Mature|World / Disease state, Lineage and Cell class

CD80 GPR141 CCR7 ATP6V0A2

2.51e-0418773451bfc450e78284796b02317e91830357850b5437
ToppCell367C-Lymphocytic-NK_cells-NK_cell_B0|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

PPM1D TSPAN8 TRMT1 PTGR3

2.51e-04187734816d37a70f7ec382a268fe828b3dfe737a36a4bf
ToppCellB_cells-Naive_B_cells_|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

OSBPL10 CD79B CCR7 CYFIP2

2.57e-04188734d1bc1316bbb8cfc39acc70f8680b14d19f536997
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KLHL29 PKHD1 OSBPL10 PTGFR

2.57e-0418873463a4b25a0a6e05f80f1a6dd91b817f3cf49e6b68
ToppCellfacs-Pancreas-Endocrine-24m|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CMIP CD79B CCR7 CYFIP2

2.62e-04189734010fdd70e9d0e21b856306a29ff877776a480319
ToppCellAdult|World / Lineage, Cell type, age group and donor

KLHL29 DUSP18 CMIP PTGFR

2.62e-041897345cd285bfad973125d46d704fec18b21266a63379
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KLHL29 PKHD1 OSBPL10 PTGFR

2.67e-041907341cf023e3c6924d6a06f353d4b62444b6f2fee8a7
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CMIP GLDC PKHD1 OSBPL10

2.67e-04190734989d4eefd22d66ecb857836f8fdbcf41e3047f84
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Ascending_Thin_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KLHL29 PKHD1 OSBPL10 PTGFR

2.67e-0419073459bbbd2c8d4b7ce46c54ca8022b1557e7e5eee2a
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-lymphocytic-B_lymphocytic-naive_B_cell|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

CDK13 OSBPL10 CD79B CCR7

2.67e-04190734a7498fe55b7810c482291db782dc5282675d246a
ToppCellPBMC-Mild-Lymphocyte-B-B_cell-B_memory-B_memory-0|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CD80 OSBPL10 CD79B CCR7

2.67e-0419073495b9334573eefb132daaa9371377ad60232006ae
ToppCelldroplet-Kidney-nan-3m-Epithelial-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPAN8 PKHD1 TMEM86A CYFIP2

2.72e-04191734297bc79adc5fef211497819b4861b52cd26ac754
ToppCelldroplet-Kidney-nan-3m-Epithelial-Epcam____thick_ascending_tube_S_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPAN8 PKHD1 TMEM86A CYFIP2

2.72e-04191734e1ec165ba6578cefd88895e7e183190e79f733a4
ToppCell(11)_FOXN4+-(0)_Reference|(11)_FOXN4+ / shred by cell type by condition

TSPAN8 PTGFR CLEC16A CYFIP2

2.78e-04192734ef06f96b934dd05b40025f8215b6d919d3a17045
ToppCellfacs-Aorta-Heart-3m|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CMIP CDK13 STAR TOP2B

2.78e-041927341ccc47792edf9ee23501c8e2165d11271636b66a
ToppCellmild_COVID-19-B_memory|World / disease group, cell group and cell class (v2)

CD80 OSBPL10 CD79B CCR7

2.83e-0419373469b70c838328fdc7dbb6b5449fe2811a5389a839
ToppCellmild_COVID-19-B_memory|mild_COVID-19 / disease group, cell group and cell class (v2)

CD80 OSBPL10 CD79B CCR7

2.83e-041937347e6fe70928a50b0a8f12220e572c07c5670d092e
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

GLDC PKHD1 OSBPL10 PTGFR

2.83e-04193734f42a0f02ed00fe1bb833ff0a0640d9131bca89bd
ToppCelldistal-Hematologic-B_cell-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

OSBPL10 MYH15 CD79B CCR7

2.83e-04193734202dc5ec2437602c15658074728c5f5aeeab0466
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

GLDC PKHD1 OSBPL10 PTGFR

2.83e-0419373442df7ed37d11fb542b4d1d714b6f87ae8e1396a6
ToppCellsevere_COVID-19-B_intermediate|World / disease group, cell group and cell class (v2)

CD80 OSBPL10 CD79B CCR7

2.89e-04194734cb346cb186fe80a8f490ae90b2539b3543ba0ca9
ToppCellCOVID-19_Severe-Non-classical_Monocyte-|COVID-19_Severe / Disease condition and Cell class

CD79B DMWD ULK2 CYFIP2

2.89e-04194734d70b9039fd2fef3e4be086513b94fb7e9bc1f670
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_B-B_mem|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

CD80 HCN1 OSBPL10 CD79B

2.89e-0419473440c7f9bd69a8e843b81972e25a67f591021415dd
ToppCellCOVID-19_Severe-Non-classical_Monocyte|COVID-19_Severe / Disease condition and Cell class

CD79B DMWD ULK2 CYFIP2

2.89e-041947345151546812678ae85cb22224084d27b29e3c4724
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_B-B_mem-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

CD80 HCN1 OSBPL10 CD79B

2.95e-0419573451e6cfecd66a874673d0b79a295489a358bddfd5
ToppCellTracheal-NucSeq-Endothelial-Endothelia_vascular-VE_systemic_arterial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CD80 OR1A1 CD79B SLC5A4

2.95e-04195734517af3e6784f02c382df6f5691945eefaa9ec4ae
ToppCellfacs-Aorta-Heart-3m-Endothelial-aorta_endothelial_cell|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JAK3 CMIP ITGB3 STAR

2.95e-041957343969b8d5fcec8ef1831531a781f7bbcebab5a4ba
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

OSBPL10 CD79B CCR7 CYFIP2

3.01e-04196734c225c8eb2fe9a10f0cf574c7d8b6206887aac2df
ToppCelldistal-1-Hematologic-B_cell|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MYH15 CD79B CCR7 CYFIP2

3.01e-04196734f442060d743b3ad2f9e5e343d4696411eef7f498
ToppCell(05)_Secretory-(0)_Reference|(05)_Secretory / shred by cell type by condition

TSPAN8 PTGFR CLEC16A CYFIP2

3.01e-041967347cb79cf122852c971f2d6e8d1e2b26eade891e83
ToppCell5'-Adult-Appendix-Hematopoietic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

JAK3 CD79B CCR7 CYFIP2

3.01e-041967343f065139f76ed048875cd6c03aa02300db2b6574
ToppCellParenchymal-NucSeq-Immune_Lymphocytic-B-B_cell|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

JAK3 OSBPL10 CD79B CCR7

3.06e-04197734ccabb976b5d4800e87e550640454a893fdb3b1b6
ToppCellmild_COVID-19-B_intermediate|mild_COVID-19 / disease group, cell group and cell class (v2)

CD80 OSBPL10 CD79B CCR7

3.06e-04197734f669500120646f69355a6f920b892a6f2faeab63
ToppCellsevere_COVID-19-B_intermediate|severe_COVID-19 / disease group, cell group and cell class (v2)

CD80 OSBPL10 CD79B CCR7

3.06e-041977343ba64850b344cb24a4d20d64392a0b2752950d40
ToppCellBAL-Control-Myeloid-cDC|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

CD80 GPR141 CCR7 KDM7A

3.06e-04197734513ada82bbbb6a624d89edaa54f8c4a303dfb5e7
ToppCellBAL-Control-Myeloid-cDC-cDC|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CD80 GPR141 CCR7 KDM7A

3.06e-041977346f83fc049f38f3de6bc5180ad4b51ceb4d5dcdb6
ToppCellControl-Myeloid-cDC|Control / Disease group,lineage and cell class (2021.01.30)

CD80 GPR141 CCR7 KDM7A

3.06e-04197734aef933107da42a763b35041c90950db07707c0cb
ToppCellBAL-Control-Myeloid-cDC-cDC|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

CD80 GPR141 CCR7 KDM7A

3.06e-0419773415e683f4a610aad3e06723747c8e56ca25f57414
ToppCellmild_COVID-19-B_intermediate|World / disease group, cell group and cell class (v2)

CD80 OSBPL10 CD79B CCR7

3.06e-04197734e909b898b7458071f176b6c04356ea3540589153
ToppCellBAL-Control-Myeloid-cDC|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CD80 GPR141 CCR7 KDM7A

3.06e-041977346ac50c02899531a25885749d5305da788dfa9dbc
ToppCell10x3'2.3-week_17-19-Lymphocytic_B|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

CDK13 CD79B GNAS TOP2B

3.12e-041987345f465cf5c7493e32d9afe9e9d05757d0a95acc33
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CACNA1B CACNA1C HCN1 GNAS

3.12e-041987348ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCellSepsis-URO-Lymphocyte-B-B_intermediate|URO / Disease, condition lineage and cell class

GLDC OSBPL10 CD79B CCR7

3.12e-04198734aea2defa941adc8eeee601885cd13817ba108e57
ToppCell10x3'2.3-week_17-19-Lymphocytic_B-B_lineage|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

CDK13 CD79B GNAS TOP2B

3.12e-0419873477ce3fe1ab161c0faf8987e73a64ab61294b9255
ToppCellTracheal-NucSeq-Immune_Lymphocytic-B-B_cell-B_mature|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CD80 CD79B CCR7 CYFIP2

3.12e-04198734863765ccc0205dc28864dae85af339c283194c96
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Neuron-Neuron|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CACNA1B HCN1 PTGFR CYFIP2

3.24e-042007342f481e2fd248c02a5aa2e0248c16808df142fed2
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW08|organoid_Tanaka_cellReport / Sample Type, Dataset, Time_group, and Cell type.

ULBP2 TAF2 ERN2 PTGFR

3.24e-042007349b614b8b949aa7d3ddbe613db6e08adaf04535a7
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Neuron-Neuron-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CACNA1B HCN1 PTGFR CYFIP2

3.24e-04200734bd4b9f6b37f4a3c960c4149cf0cfd2caf3327d2d
DrugHCNs

HCN4 HCN1 HCN3 HCN2

4.53e-0720734CID006857665
Drugloperamide

CACNA1B CACNA1C TRPA1 HCN4 HCN1 RYR1

1.10e-06105736CID000003954
Druglercanidipine

CACNA1B CACNA1C TRPA1 HCN4 RYR1

1.79e-0663735CID000065866
DrugCNS 1145

CACNA1B CACNA1C TRPA1 RYR1

3.71e-0633734CID000190902
DrugIHC-64

CACNA1B CACNA1C TRPA1 RYR1

3.71e-0633734CID000162753
Drugethosuximide

CACNA1B CACNA1C TRPA1 HCN1 RYR1

4.00e-0674735CID000003291
Drug8-bromoguanosine 3',5'-cyclic monophosphate

CACNA1B CACNA1C TRPA1 HCN4 HCN1 HCN3 TOP2B RYR1

6.42e-06308738CID000001915
Drugcapsazepine

CACNA1B CACNA1C TRPA1 HCN1 HCN2

7.47e-0684735CID002733484
Drugmenthol

TRPA1 HCN4 HCN1 HCN2 TOP2B

8.88e-0687735CID000001254
Drugzatebradine

HCN4 HCN1 HCN2

2.08e-0517733CID000065637
DrugAC1L1GTQ

CACNA1B CACNA1C ITGB3 RYR1

2.72e-0554734CID000003836
Drugzatebradine

HCN4 HCN2

3.04e-053732ctd:C043636
DrugCinildipine

CACNA1B CACNA1C TRPA1 RYR1

3.15e-0556734CID000002752
DrugCID5255110

HCN4 HCN1 HCN3 HCN2

3.38e-0557734CID005255110
DrugPilocarpine

CACNA1B CACNA1C MTOR HCN1 CCR7 ITGB3 STAR

3.60e-05285737ctd:D010862
DrugAC1NBU2S

CACNA1B CACNA1C TRPA1 STAR RYR1

3.74e-05117735CID004473765
DrugColistin sulfate [1264-72-8]; Up 200; 3uM; MCF7; HT_HG-U133A

KLHL29 MTOR ASAP3 ERN2 ULK2 RYR1

3.97e-051967362851_UP
Drugnilvadipine

CACNA1B CACNA1C TRPA1 RYR1

4.14e-0560734CID000004494
Drug(S)-(-)-Atenolol [93379-54-5]; Up 200; 15uM; HL60; HT_HG-U133A

CD80 ASAP3 HUWE1 ERN2 ITGB3 CYFIP2

4.21e-051987363067_UP
DrugDicumarol [66-76-2]; Up 200; 11.8uM; MCF7; HT_HG-U133A

CD80 OR1A1 ASAP3 CD79B ITGB3 RYR1

4.21e-051987363941_UP
DrugIAA-94

CACNA1B CACNA1C TRPA1 RYR1

4.42e-0561734CID000003667
DrugClomipramine hydrochloride [17321-77-6]; Up 200; 11.4uM; MCF7; HT_HG-U133A

HCN4 CDK13 CD80 MYH15 PTGFR ITGB3

4.45e-052007363182_UP
DrugEpivincamine [6835-99-0]; Up 200; 11.2uM; MCF7; HT_HG-U133A

CDK13 ASAP3 CCR7 ITGB3 ULK2 RYR1

4.45e-052007366838_UP
Druggenistein

SCRT2 JAK3 CACNA1B CACNA1C TRPA1 MTOR HCN1 MAZ ITGB3 KAT14 STAR TOP2B RYR1

4.94e-0511177313CID005280961
Druggallopamil

CACNA1B CACNA1C TRPA1 RYR1

6.40e-0567734CID000001234
DrugAC1L2AC7

CACNA1B CACNA1C TRPA1 RYR1

7.18e-0569734CID000068733
DrugCAS 298-57-7

CACNA1B CACNA1C TRPA1 RYR1

8.95e-0573734CID000002761
DrugDantrolene-13C3

CACNA1B CACNA1C TRPA1 DMWD RYR1

1.04e-04145735CID000002951
DrugNSC683246

CACNA1B CACNA1C MTOR CDK13 HCN1 PKHD1

1.06e-04234736CID000005097
Drugnisoldipine

CACNA1B CACNA1C TRPA1 RYR1

1.16e-0478734CID000004499
Drug6-carboxyfluorescein diacetate

MTOR CD80 ATP6V0A2

1.21e-0430733CID000151095
DrugN-cyclopentyl-N-cyclobutylformamide

CACNA1B CACNA1C TRPA1 RYR1

1.22e-0479734CID005287890
Diseaselevel of UL16-binding protein 6 in blood serum

ULBP2 RAET1L

5.55e-062702OBA_2043185
Diseasemeningitis (biomarker_via_orthology)

HCN1 HCN2

5.55e-062702DOID:9471 (biomarker_via_orthology)
Diseasesick sinus syndrome (implicated_via_orthology)

HCN4 HCN1

1.66e-053702DOID:13884 (implicated_via_orthology)
DiseaseEndocrine System Diseases

MTOR GNAS

1.66e-053702C0014130
Diseasehexanoylglycine measurement

GPR142 GLDC

1.16e-047702EFO_0800233
DiseaseBrugada syndrome

CACNA1C HCN4

1.54e-048702cv:C1142166
Diseasesyndromic X-linked intellectual disability (implicated_via_orthology)

KDM7A HUWE1

1.54e-048702DOID:0060309 (implicated_via_orthology)
Diseasebody weight

NPC1 CACNA1B CACNA1C COPG1 MTOR ZNF280C TSPAN8 CD79B GNAS HUWE1 EFR3A

1.77e-0412617011EFO_0004338
DiseaseTremor, Rubral

NPC1 HCN1

6.52e-0416702C0750940
DiseaseAtaxia, Appendicular

NPC1 HCN1

6.52e-0416702C0750937
DiseaseAtaxia, Motor

NPC1 HCN1

6.52e-0416702C0278161
DiseaseAbnormal coordination

NPC1 HCN1

6.52e-0416702C0520966
Diseaseautosomal recessive polycystic kidney disease (implicated_via_orthology)

MTOR PKHD1

6.52e-0416702DOID:0110861 (implicated_via_orthology)
DiseaseAtaxia, Truncal

NPC1 HCN1

6.52e-0416702C0427190
DiseaseAtaxia, Sensory

NPC1 HCN1

6.52e-0416702C0240991
Diseasebody surface area

KLHL29 COPG1 MTOR PKHD1 CD79B GNAS ITGB3

8.25e-04643707EFO_0022196
Diseasepolycystic kidney disease (biomarker_via_orthology)

MTOR GNAS

9.24e-0419702DOID:0080322 (biomarker_via_orthology)
DiseaseAnhedonia

CACNA1C CCR7

1.48e-0324702C0178417
DiseaseBrugada Syndrome (disorder)

CACNA1C HCN4

1.48e-0324702C1142166
DiseaseAtaxia

NPC1 HCN1

1.61e-0325702C0004134

Protein segments in the cluster

PeptideGeneStartEntry
LHMCEYLLKAGESQM

ASAP3

191

Q8TDY4
LMASPSMEDLYHKSC

CCAR1

451

Q8IX12
YKMSFFSGMLLLLCI

CCR7

136

P32248
ELFASMVHILMGSCY

CMIP

541

Q8IY22
MACAHRALEMGIKYL

CFAP46

956

Q8IYW2
MTLQELVHKAASCYM

AASDH

1

Q4L235
EGHRMLAMSYTCQAK

ANKRD50

431

Q9ULJ7
FNMTTNHSFMCLIKY

CD80

206

P33681
CGRISYNDMFEMLKH

CACNA1B

1741

Q00975
FHFDSMLLRGLMKSY

DMWD

311

Q09019
KRGFTVKMHCYMNSA

CD79B

56

P40259
SFMRQLMEGLDYCHK

CDK13

816

Q14004
MFHRCGIMALVAAYL

EFR3A

591

Q14156
ACQADRHSLMAKYIM

JAK3

226

P52333
PFCKFVSAMLHIHMY

GPR141

86

Q7Z602
MSMGLLHFYKSRSCS

ODF4

131

Q2M2E3
KLSCSDVHFNVKMMY

OR1A2

186

Q9Y585
QGMLSMAGLHYSTCL

KDM7A

736

Q6ZMT4
KYMSHLASCGMGLLL

ERN2

196

Q76MJ5
HVKMMLSGVCLFAVF

PTGFR

151

P43088
ATFMIYHLIQTCMGK

KAT14

716

Q9H8E8
VCGKMLSSAYISDHM

MAZ

396

P56270
MAMASFYHARCLQLG

LRP2BP

296

Q9P2M1
KYLMGEHGQSCAKML

PPM1D

336

O15297
LCKHMTLDSFDAMFR

CYFIP2

836

Q96F07
ALFKAMSHMLCIGYG

HCN3

301

Q9P1Z3
LTAAHAYIMMFVHTC

HUWE1

896

Q7Z6Z7
SYALFKAMSHMLCIG

HCN4

466

Q9Y3Q4
AFAHTECLILVMMSY

OR2A5

106

Q96R48
MFLYISLALGHMKSC

NPC1

631

O15118
SYALFKAMSHMLCIG

HCN1

346

O60741
KAMSHMLCIGYGAQA

HCN1

351

O60741
GLELFMGKMHKTCYN

CACNA1C

286

Q13936
MVAMLHTAANFGLYC

GPR142

401

Q7Z601
SHNKACTMLFMILYF

FZD3

281

Q9NPG1
MKTTCLPMFGYKHVL

ITGB3

206

P05106
HGLKSPFAYCMMIRV

COPG1

221

Q9Y678
MRALFGLYMSASHIA

EMC2

226

Q15006
LKDLMRASYPCMSLH

DDX46

636

Q7L014
LYMAYADIMAKSCHL

RYR1

3721

P21817
FALFKAMSHMLCIGY

HCN2

416

Q9UL51
HPLHYSSMMSKVFCS

OR13A1

146

Q8NGR1
KLSCSDIHFHVKMMY

OR1A1

186

Q9P1Q5
AYGAMVSCHMLSELE

MTOR

1586

P42345
IFAIAECHMLAAMAY

OR8G3P

106

P0DMU2
SGSKIRAFMMCLHAY

RNF139

491

Q8WU17
KYGAMALKSRACHEM

TRMT1

276

Q9NXH9
CGKAYVSMPALAMHL

SCRT2

191

Q9NQ03
MVLFDHMGCLKKYET

TOP2B

1021

Q02880
YSMFQCKAHLVMRLI

TAF2

446

Q6P1X5
CYKLTGAIMHFGNMK

MYH15

361

Q9Y2K3
EKMGYMCTHRLLLLG

GNAS

676

Q5JWF2
YVSLFKHQMLCDMAR

NICN1

96

Q9BSH3
DMSHVKAACIMCAYL

SLC5A4

306

Q9NY91
KAMLFMCSGSIIHNL

MT-ND5

336

P03915
YVAICKPLHYMAIMS

OR6C68

121

A6NDL8
LQHCLYSMSEKMLGS

PKHD1

2166

P08F94
HYSTFMSKQVCLALM

OR5AR1

131

Q8NGP9
AMIKMVFIAQLHYCG

OR6Y1

161

Q8NGX8
LRACAKYHMEMNSKS

OSBPL10

166

Q9BXB5
VLCLLYAMSHNKGMD

CLEC16A

501

Q2KHT3
GLLMFAVTHMFYASA

TMEM86A

96

Q8N2M4
FRAHMMNLGSYCLGL

TRPA1

716

O75762
MDSYTMRFCGHLAAV

RNF112

536

Q9ULX5
FKLCAGSSYRHMRNM

STAR

6

P49675
KDVAMSFHYISMGDC

RAET1L

176

Q5VY80
KYQAAMSHLLEMCVS

PTGR3

311

Q8N4Q0
FARYLHSNMMAATLC

ULK2

161

Q8IYT8
MMKSSDCVIKHAGVY

ZNF330

76

Q9Y3S2
FCLKVSKMATPYMNH

ZNF280C

446

Q8ND82
KVVAMSFHYFSMGDC

ULBP2

176

Q9BZM5
MAGVSACIKYSMFTF

TSPAN8

1

P19075
KAIYHMLNMCSFDVT

ATP6V0A2

306

Q9Y487
SAALCLAYLMKYHAM

DUSP18

111

Q8NEJ0
ALLANMAAMFAIYHG

GLDC

386

P23378
MQCSELYHMAKAFAL

KLHL29

446

Q96CT2