Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ABC-type transporter activity	ABCC3 ABCA4 ATP13A1 ABCA10 ABCA9 ABCA6 ABCA5	1.09e-08	49	113	7	GO:0140359
GeneOntologyMolecularFunction	active transmembrane transporter activity	ABCC3 SLC29A3 ABCA4 SLC2A8 ATP13A1 SLC26A2 SLC26A4 ABCA10 ABCA9 SLC6A9 SLC39A12 SLC10A1 SLCO1C1 ABCA6 ABCA5	8.02e-08	477	113	15	GO:0022804
GeneOntologyMolecularFunction	transmembrane transporter activity	CACNA1E ABCC3 SLC29A3 ABCA4 SLC2A8 ATP13A1 SLC26A2 SLC26A4 BAX ABCA10 ABCA9 SLC6A9 SLC39A12 SLC10A1 SLCO1C1 ATP11B P2RX4 P2RX7 ABCA6 ABCA5 TRPM8 TRPV3	6.47e-07	1180	113	22	GO:0022857
GeneOntologyMolecularFunction	lipid transporter activity	ABCC3 ABCA4 ABCA10 ABCA9 SLC10A1 SLCO1C1 ATP11B ABCA6 ABCA5	1.74e-06	196	113	9	GO:0005319
GeneOntologyMolecularFunction	transporter activity	CACNA1E ABCC3 SLC29A3 ABCA4 SLC2A8 ATP13A1 SLC26A2 SLC26A4 BAX ABCA10 ABCA9 SLC6A9 SLC39A12 SLC10A1 SLCO1C1 ATP11B P2RX4 P2RX7 ABCA6 ABCA5 TRPM8 TRPV3	2.79e-06	1289	113	22	GO:0005215
GeneOntologyMolecularFunction	ATPase-coupled transmembrane transporter activity	ABCC3 ABCA4 ATP13A1 ABCA10 ABCA9 ABCA6 ABCA5	2.85e-06	109	113	7	GO:0042626
GeneOntologyMolecularFunction	primary active transmembrane transporter activity	ABCC3 ABCA4 ATP13A1 ABCA10 ABCA9 ABCA6 ABCA5	6.94e-05	178	113	7	GO:0015399
GeneOntologyMolecularFunction	carnitine O-palmitoyltransferase activity	CPT1A CPT1B	1.89e-04	4	113	2	GO:0004095
GeneOntologyMolecularFunction	organic anion transmembrane transporter activity	ABCC3 SLC2A8 SLC26A2 SLC26A4 SLC6A9 SLC39A12 SLC10A1 SLCO1C1	2.64e-04	293	113	8	GO:0008514
GeneOntologyMolecularFunction	O-palmitoyltransferase activity	CPT1A CPT1B	3.14e-04	5	113	2	GO:0016416
GeneOntologyMolecularFunction	carnitine O-acyltransferase activity	CPT1A CPT1B	4.69e-04	6	113	2	GO:0016406
GeneOntologyMolecularFunction	phosphatidylethanolamine flippase activity	ABCA4 ATP11B	6.54e-04	7	113	2	GO:0090555
GeneOntologyMolecularFunction	extracellularly ATP-gated monoatomic cation channel activity	P2RX4 P2RX7	6.54e-04	7	113	2	GO:0004931
GeneOntologyMolecularFunction	organic hydroxy compound transmembrane transporter activity	ABCC3 ABCA4 SLC10A1 SLCO1C1	6.69e-04	70	113	4	GO:1901618
GeneOntologyMolecularFunction	bicarbonate transmembrane transporter activity	SLC26A2 SLC26A4 SLC39A12	7.77e-04	32	113	3	GO:0015106
GeneOntologyMolecularFunction	lipid transmembrane transporter activity	ABCC3 ABCA4 SLC10A1 SLCO1C1	7.84e-04	73	113	4	GO:0170055
GeneOntologyMolecularFunction	ATP hydrolysis activity	ABCC3 ABCA4 DYNC2H1 ATP13A1 ABCA10 ABCA9 ATP11B ABCA6 ABCA5	9.07e-04	441	113	9	GO:0016887
GeneOntologyMolecularFunction	bile acid transmembrane transporter activity	ABCC3 SLC10A1 SLCO1C1	9.29e-04	34	113	3	GO:0015125
GeneOntologyMolecularFunction	ATP-gated ion channel activity	P2RX4 P2RX7	1.11e-03	9	113	2	GO:0035381
GeneOntologyMolecularFunction	RNA polymerase I general transcription initiation factor activity	RRN3 RRN3P1	1.11e-03	9	113	2	GO:0001181
GeneOntologyMolecularFunction	protein kinase inhibitor activity	CASP3 DUS2 PRKAR1A PRKAR1B	1.16e-03	81	113	4	GO:0004860
GeneOntologyMolecularFunction	carboxylic acid transmembrane transporter activity	ABCC3 SLC26A2 SLC26A4 SLC6A9 SLC10A1 SLCO1C1	1.16e-03	207	113	6	GO:0046943
GeneOntologyMolecularFunction	organic acid transmembrane transporter activity	ABCC3 SLC26A2 SLC26A4 SLC6A9 SLC10A1 SLCO1C1	1.19e-03	208	113	6	GO:0005342
GeneOntologyMolecularFunction	dynein intermediate chain binding	DYNC2H1 DNAH17 HTT	1.19e-03	37	113	3	GO:0045505
GeneOntologyMolecularFunction	oxalate transmembrane transporter activity	SLC26A2 SLC26A4	1.39e-03	10	113	2	GO:0019531
GeneOntologyMolecularFunction	cAMP-dependent protein kinase inhibitor activity	PRKAR1A PRKAR1B	1.39e-03	10	113	2	GO:0004862
GeneOntologyMolecularFunction	kinase inhibitor activity	CASP3 DUS2 PRKAR1A PRKAR1B	1.45e-03	86	113	4	GO:0019210
GeneOntologyMolecularFunction	secondary active transmembrane transporter activity	SLC2A8 SLC26A2 SLC26A4 SLC6A9 SLC39A12 SLC10A1 SLCO1C1	1.48e-03	296	113	7	GO:0015291
GeneOntologyMolecularFunction	protein serine/threonine kinase inhibitor activity	CASP3 PRKAR1A PRKAR1B	1.61e-03	41	113	3	GO:0030291
GeneOntologyMolecularFunction	secondary active sulfate transmembrane transporter activity	SLC26A2 SLC26A4	1.69e-03	11	113	2	GO:0008271
GeneOntologyMolecularFunction	monoatomic ion transmembrane transporter activity	CACNA1E ATP13A1 SLC26A2 SLC26A4 SLC6A9 SLC39A12 SLC10A1 ATP11B P2RX4 P2RX7 TRPM8 TRPV3	1.78e-03	793	113	12	GO:0015075
GeneOntologyMolecularFunction	cAMP-dependent protein kinase regulator activity	PRKAR1A PRKAR1B	2.38e-03	13	113	2	GO:0008603
GeneOntologyMolecularFunction	ATP-dependent activity	ABCC3 ABCA4 DYNC2H1 ATP13A1 ABCA10 ABCA9 ATP11B ABCA6 ABCA5 DNAH17	2.55e-03	614	113	10	GO:0140657
GeneOntologyMolecularFunction	glycerophospholipid flippase activity	ABCA4 ATP11B	2.76e-03	14	113	2	GO:0140333
GeneOntologyMolecularFunction	protein kinase regulator activity	CASP3 CCNG1 DUS2 P2RX7 PRKAR1A PRKAR1B	3.57e-03	259	113	6	GO:0019887
GeneOntologyMolecularFunction	sulfate transmembrane transporter activity	SLC26A2 SLC26A4	3.62e-03	16	113	2	GO:0015116
GeneOntologyMolecularFunction	protein kinase A catalytic subunit binding	PRKAR1A PRKAR1B	3.62e-03	16	113	2	GO:0034236
GeneOntologyMolecularFunction	inorganic molecular entity transmembrane transporter activity	CACNA1E ABCC3 ATP13A1 SLC26A2 SLC26A4 SLC6A9 SLC39A12 SLC10A1 P2RX4 TRPM8 TRPV3	3.80e-03	758	113	11	GO:0015318
GeneOntologyMolecularFunction	flippase activity	ABCA4 ATP11B	4.08e-03	17	113	2	GO:0140327
GeneOntologyMolecularFunction	protein kinase A binding	ARFGEF2 PRKAR1A PRKAR1B	4.34e-03	58	113	3	GO:0051018
GeneOntologyMolecularFunction	minus-end-directed microtubule motor activity	DYNC2H1 DNAH17	4.58e-03	18	113	2	GO:0008569
GeneOntologyMolecularFunction	metal ion transmembrane transporter activity	CACNA1E ATP13A1 SLC6A9 SLC39A12 SLC10A1 P2RX4 TRPM8 TRPV3	4.95e-03	465	113	8	GO:0046873
GeneOntologyMolecularFunction	sulfur compound transmembrane transporter activity	ABCC3 SLC26A2 SLC26A4	5.00e-03	61	113	3	GO:1901682
GeneOntologyBiologicalProcess	lipid transport	ABCC3 ABCA4 RUNX1 CPT1A CPT1B ABCA10 ABCA9 SLC10A1 SLCO1C1 ATP11B P2RX4 P2RX7 ABCA6 ABCA5	4.55e-07	506	109	14	GO:0006869
GeneOntologyBiologicalProcess	lipid localization	ABCC3 ABCA4 RUNX1 CPT1A CPT1B ABCA10 ABCA9 SLC10A1 SLCO1C1 ATP11B P2RX4 P2RX7 ABCA6 ABCA5	1.68e-06	565	109	14	GO:0010876
GeneOntologyBiologicalProcess	cilium movement involved in cell motility	MKKS CFAP47 CACNA1E DYNC2H1 ADCY3 CFAP65 DNAH17 IRGC	1.59e-05	210	109	8	GO:0060294
GeneOntologyBiologicalProcess	positive regulation of calcium ion transport	MCHR1 BAX CEMIP P2RX4 P2RX7 TRPV3 HTT	1.78e-05	154	109	7	GO:0051928
GeneOntologyBiologicalProcess	organic anion transport	ABCC3 SLC2A8 SLC26A2 SLC26A4 CPT1A CPT1B SLC6A9 SLC39A12 SLC10A1 SLCO1C1 P2RX4 P2RX7	1.80e-05	515	109	12	GO:0015711
GeneOntologyBiologicalProcess	cilium-dependent cell motility	MKKS CFAP47 CACNA1E DYNC2H1 ADCY3 CFAP65 DNAH17 IRGC	1.89e-05	215	109	8	GO:0060285
GeneOntologyBiologicalProcess	cilium or flagellum-dependent cell motility	MKKS CFAP47 CACNA1E DYNC2H1 ADCY3 CFAP65 DNAH17 IRGC	1.89e-05	215	109	8	GO:0001539
GeneOntologyBiologicalProcess	phospholipid transfer to membrane	ABCA4 P2RX7	2.77e-05	2	109	2	GO:0006649
GeneOntologyBiologicalProcess	carboxylic acid transport	ABCC3 SLC26A2 SLC26A4 CPT1A CPT1B SLC6A9 SLC10A1 SLCO1C1 P2RX4 P2RX7	6.39e-05	410	109	10	GO:0046942
GeneOntologyBiologicalProcess	organic acid transport	ABCC3 SLC26A2 SLC26A4 CPT1A CPT1B SLC6A9 SLC10A1 SLCO1C1 P2RX4 P2RX7	6.66e-05	412	109	10	GO:0015849
GeneOntologyBiologicalProcess	cilium movement	MKKS CFAP47 CACNA1E DYNC2H1 ADCY3 CFAP65 DNAH17 IRGC	7.46e-05	261	109	8	GO:0003341
GeneOntologyBiologicalProcess	regulation of cAMP-dependent protein kinase activity	PRKAR1A PRKAR1B HTT	7.65e-05	16	109	3	GO:2000479
GeneOntologyBiologicalProcess	monoatomic ion transport	CACNA1E ABCC3 DPP10 MCHR1 ATP13A1 SLC26A2 SLC26A4 BAX CEMIP SLC6A9 SLC39A12 SLC10A1 SLCO1C1 ATP11B P2RX4 P2RX7 TRPM8 TRPV3 HTT	9.92e-05	1374	109	19	GO:0006811
GeneOntologyBiologicalProcess	monocarboxylic acid transport	ABCC3 CPT1A CPT1B SLC10A1 SLCO1C1 P2RX4 P2RX7	1.39e-04	213	109	7	GO:0015718
GeneOntologyBiologicalProcess	calcium ion transmembrane import into cytosol	CACNA1E BAX CEMIP P2RX4 P2RX7 TRPV3 HTT	1.56e-04	217	109	7	GO:0097553
GeneOntologyBiologicalProcess	carnitine shuttle	CPT1A CPT1B	1.65e-04	4	109	2	GO:0006853
GeneOntologyBiologicalProcess	positive regulation of calcium ion transport into cytosol	BAX P2RX4 P2RX7	1.78e-04	21	109	3	GO:0010524
GeneOntologyBiologicalProcess	monoatomic ion transmembrane transport	CACNA1E ABCC3 DPP10 ATP13A1 SLC26A2 SLC26A4 BAX CEMIP SLC6A9 SLC39A12 ATP11B P2RX4 P2RX7 TRPM8 TRPV3 HTT	2.48e-04	1115	109	16	GO:0034220
GeneOntologyBiologicalProcess	negative regulation of cAMP/PKA signal transduction	PRKAR1A PRKAR1B	2.74e-04	5	109	2	GO:0141162
GeneOntologyBiologicalProcess	positive regulation of calcium ion transmembrane transport	BAX CEMIP P2RX4 P2RX7 HTT	2.84e-04	109	109	5	GO:1904427
GeneOntologyBiologicalProcess	transmission of nerve impulse	CACNA1E PRX GHSR P2RX4 P2RX7	3.22e-04	112	109	5	GO:0019226
GeneOntologyBiologicalProcess	regulation of calcium ion transport into cytosol	BAX P2RX4 P2RX7	3.83e-04	27	109	3	GO:0010522
GeneOntologyBiologicalProcess	anatomical structure homeostasis	MKKS ABCA4 LAMA2 BAX DLK1 PROM1 P2RX4 P2RX7	4.00e-04	334	109	8	GO:0060249
GeneOntologyBiologicalProcess	tissue homeostasis	MKKS ABCA4 LAMA2 BAX DLK1 PROM1 P2RX4 P2RX7	4.00e-04	334	109	8	GO:0001894
Domain	ABC_A	ABCA4 ABCA10 ABCA9 ABCA6 ABCA5	4.31e-09	12	107	5	IPR026082
Domain	ABC_tran	ABCC3 ABCA4 ABCA10 ABCA9 ABCA6 ABCA5	3.10e-07	48	107	6	PF00005
Domain	ABC_TRANSPORTER_2	ABCC3 ABCA4 ABCA10 ABCA9 ABCA6 ABCA5	3.10e-07	48	107	6	PS50893
Domain	ABC_TRANSPORTER_1	ABCC3 ABCA4 ABCA10 ABCA9 ABCA6 ABCA5	3.51e-07	49	107	6	PS00211
Domain	ABC_transporter-like	ABCC3 ABCA4 ABCA10 ABCA9 ABCA6 ABCA5	3.97e-07	50	107	6	IPR003439
Domain	AAA	ABCC3 ABCA4 DYNC2H1 ABCA10 ABCA9 ABCA6 ABCA5	1.92e-05	144	107	7	SM00382
Domain	AAA+_ATPase	ABCC3 ABCA4 DYNC2H1 ABCA10 ABCA9 ABCA6 ABCA5	1.92e-05	144	107	7	IPR003593
Domain	ABC_transporter_CS	ABCC3 ABCA4 ABCA10 ABCA5	9.64e-05	42	107	4	IPR017871
Domain	CPT_N	CPT1A CPT1B	9.72e-05	3	107	2	IPR032476
Domain	CPT_N	CPT1A CPT1B	9.72e-05	3	107	2	PF16484
Domain	cAMP_dep_PK_reg_su	PRKAR1A PRKAR1B	1.94e-04	4	107	2	IPR012198
Domain	RIIa	PRKAR1A PRKAR1B	4.80e-04	6	107	2	SM00394
Domain	P2X_receptor	P2RX4 P2RX7	6.70e-04	7	107	2	PF00864
Domain	P2X_purnocptor	P2RX4 P2RX7	6.70e-04	7	107	2	IPR001429
Domain	Carn_acyl_trans	CPT1A CPT1B	6.70e-04	7	107	2	IPR000542
Domain	S04_transporter_CS	SLC26A2 SLC26A4	6.70e-04	7	107	2	IPR018045
Domain	-	P2RX4 P2RX7	6.70e-04	7	107	2	2.60.490.10
Domain	RIIa	PRKAR1A PRKAR1B	6.70e-04	7	107	2	PF02197
Domain	Carn_acyltransf	CPT1A CPT1B	6.70e-04	7	107	2	PF00755
Domain	ACYLTRANSF_C_1	CPT1A CPT1B	6.70e-04	7	107	2	PS00439
Domain	ACYLTRANSF_C_2	CPT1A CPT1B	6.70e-04	7	107	2	PS00440
Domain	P2X_RECEPTOR	P2RX4 P2RX7	6.70e-04	7	107	2	PS01212
Domain	P2X_extracellular_dom	P2RX4 P2RX7	6.70e-04	7	107	2	IPR027309
Domain	SLC26A	SLC26A2 SLC26A4	1.42e-03	10	107	2	PS01130
Domain	STAS	SLC26A2 SLC26A4	1.73e-03	11	107	2	PS50801
Domain	STAS	SLC26A2 SLC26A4	1.73e-03	11	107	2	PF01740
Domain	SLC26A/SulP_fam	SLC26A2 SLC26A4	1.73e-03	11	107	2	IPR001902
Domain	STAS_dom	SLC26A2 SLC26A4	1.73e-03	11	107	2	IPR002645
Domain	SLC26A/SulP_dom	SLC26A2 SLC26A4	1.73e-03	11	107	2	IPR011547
Domain	-	SLC26A2 SLC26A4	1.73e-03	11	107	2	3.30.750.24
Domain	Sulfate_transp	SLC26A2 SLC26A4	1.73e-03	11	107	2	PF00916
Domain	cAMP_dep_PK_reg_su_I/II_a/b	PRKAR1A PRKAR1B	3.25e-03	15	107	2	IPR003117
Domain	cNMP-bd_CS	PRKAR1A PRKAR1B	3.70e-03	16	107	2	IPR018488
Domain	ARM-like	ARFGEF2 CUL9 HUWE1 TTI1 UTP20 HTT	4.62e-03	270	107	6	IPR011989
Pathway	REACTOME_TRANSPORT_OF_SMALL_MOLECULES	ABCC3 SLC29A3 ABCA4 SLC2A8 ATP13A1 SLC26A2 SLC26A4 RUNX1 ABCA10 ADCY3 ABCA9 SLC6A9 SLCO1C1 ATP11B ABCA6 ABCA5 PRKAR1A PRKAR1B TRPM8 TRPV3	1.52e-08	736	87	20	M27287
Pathway	KEGG_ABC_TRANSPORTERS	ABCC3 ABCA4 ABCA10 ABCA9 ABCA6 ABCA5	2.71e-07	44	87	6	M11911
Pathway	REACTOME_TRANSPORT_OF_SMALL_MOLECULES	ABCC3 SLC29A3 ABCA4 SLC2A8 ATP13A1 SLC26A2 SLC26A4 ABCA9 SLC6A9 SLCO1C1 ATP11B ABCA6 ABCA5 PRKAR1A PRKAR1B TRPM8 TRPV3	7.23e-07	681	87	17	MM14985
Pathway	REACTOME_ABC_TRANSPORTERS_IN_LIPID_HOMEOSTASIS	ABCA10 ABCA9 ABCA6 ABCA5	3.88e-06	18	87	4	M524
Pathway	REACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT	ABCC3 ABCA4 ABCA10 ABCA9 ABCA6 ABCA5	4.11e-05	103	87	6	M758
Pathway	REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB	ADCY3 PRKAR1A PRKAR1B	1.20e-04	16	87	3	MM14492
Pathway	WP_NUCLEAR_RECEPTORS_METAPATHWAY	ABCC3 SLC2A8 SLC26A2 BAX CPT1A SLC6A9 SLC39A12 FASN SLC10A1	1.34e-04	314	87	9	M39428
Pathway	REACTOME_PKA_ACTIVATION_IN_GLUCAGON_SIGNALLING	ADCY3 PRKAR1A PRKAR1B	1.45e-04	17	87	3	M26995
Pathway	REACTOME_ABC_TRANSPORTERS_IN_LIPID_HOMEOSTASIS	ABCA9 ABCA6 ABCA5	1.45e-04	17	87	3	MM14552
Pathway	REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB	ADCY3 PRKAR1A PRKAR1B	2.40e-04	20	87	3	M759
Pathway	REACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT	ABCC3 ABCA4 ABCA9 ABCA6 ABCA5	3.62e-04	99	87	5	MM14986
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_EXTRINSIC_APOPTOTIC_PATHWAY	CASP3 HTT	3.72e-04	5	87	2	M48989
Pathway	BIOCARTA_BAD_PATHWAY	BAX PRKAR1A PRKAR1B	4.18e-04	24	87	3	MM1467
Pathway	WP_EFFECTS_OF_MFN2_MUTATION	DYNC2H1 CASP3 BAX	4.18e-04	24	87	3	M48308
Pathway	BIOCARTA_BAD_PATHWAY	BAX PRKAR1A PRKAR1B	4.73e-04	25	87	3	M85
Pathway	REACTOME_CA_DEPENDENT_EVENTS	ADCY3 PRKAR1A PRKAR1B	5.33e-04	26	87	3	MM14495
Pathway	REACTOME_INTEGRATION_OF_ENERGY_METABOLISM	CACNA1E ADCY3 FASN PRKAR1A PRKAR1B	5.40e-04	108	87	5	M17034
Pathway	REACTOME_GLUCAGON_SIGNALING_IN_METABOLIC_REGULATION	PRKAR1A PRKAR1B	5.56e-04	6	87	2	MM14628
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PRKN_TO_INTRINSIC_APOPTOTIC_PATHWAY	CASP3 BAX	5.56e-04	6	87	2	M47708
Pathway	WP_LIPID_METABOLISM_PATHWAY	FASN PRKAR1A PRKAR1B	7.39e-04	29	87	3	M39762
Pathway	KEGG_MEDICUS_PATHOGEN_EBV_BARF1_TO_INTRINSIC_APOPTOTIC_PATHWAY	CASP3 BAX	7.75e-04	7	87	2	M47577
Pathway	KEGG_MEDICUS_REFERENCE_PKA_HOLOENZYME	PRKAR1A PRKAR1B	7.75e-04	7	87	2	M47896
Pathway	KEGG_MEDICUS_VARIANT_BCL2_OVEREXPRESSION_TO_INTRINSIC_APOPTOTIC_PATHWAY	CASP3 BAX	7.75e-04	7	87	2	M47435
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PINK1_TO_INTRINSIC_APOPTOTIC_PATHWAY_N01050	CASP3 BAX	7.75e-04	7	87	2	M47709
Pathway	REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT	SLC29A3 SLC2A8 SLC26A2 SLC26A4 RUNX1 SLC6A9 SLCO1C1	8.67e-04	249	87	7	M5988
Pathway	KEGG_MEDICUS_PATHOGEN_HIV_TAT_NEF_TO_CROSSTALK_BETWEEN_EXTRINSIC_AND_INTRINSIC_APOPTOTIC_PATHWAYS	CASP3 BAX	1.03e-03	8	87	2	M47571
Pathway	WP_PEROXIREDOXIN_2_INDUCED_OVARIAN_FAILURE	CASP3 BAX	1.03e-03	8	87	2	MM15965
Pathway	WP_EPAC1_AND_PKA_REDUCTION_OF_RETINAL_INFLAMMATION	PRKAR1A PRKAR1B	1.03e-03	8	87	2	M48325
Pathway	WP_PEROXIREDOXIN_2_INDUCED_OVARIAN_FAILURE	CASP3 BAX	1.03e-03	8	87	2	M39906
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SOD1_TO_INTRINSIC_APOPTOTIC_PATHWAY	CASP3 BAX	1.03e-03	8	87	2	M47740
Pathway	PID_INTEGRIN_A4B1_PATHWAY	ADAM28 PRKAR1A PRKAR1B	1.08e-03	33	87	3	M277
Pathway	REACTOME_GLUCAGON_SIGNALING_IN_METABOLIC_REGULATION	ADCY3 PRKAR1A PRKAR1B	1.08e-03	33	87	3	M11575
Pathway	REACTOME_MULTIFUNCTIONAL_ANION_EXCHANGERS	SLC26A2 SLC26A4	1.32e-03	9	87	2	M27344
Pathway	REACTOME_MULTIFUNCTIONAL_ANION_EXCHANGERS	SLC26A2 SLC26A4	1.32e-03	9	87	2	MM15084
Pathway	REACTOME_CA_DEPENDENT_EVENTS	ADCY3 PRKAR1A PRKAR1B	1.52e-03	37	87	3	M749
Pathway	BIOCARTA_AGPCR_PATHWAY	PRKAR1A PRKAR1B	1.64e-03	10	87	2	MM1352
Pathway	BIOCARTA_CHREBP_PATHWAY	PRKAR1A PRKAR1B	1.64e-03	10	87	2	MM1530
Pathway	BIOCARTA_CFTR_PATHWAY	PRKAR1A PRKAR1B	1.64e-03	10	87	2	MM1377
Pathway	REACTOME_G_PROTEIN_MEDIATED_EVENTS	ADCY3 PRKAR1A PRKAR1B	1.77e-03	39	87	3	MM14496
Pathway	BIOCARTA_CARM1_PATHWAY	PRKAR1A PRKAR1B	2.00e-03	11	87	2	MM1521
Pathway	BIOCARTA_PLCE_PATHWAY	PRKAR1A PRKAR1B	2.00e-03	11	87	2	M5576
Pathway	KEGG_MEDICUS_REFERENCE_BETA_OXIDATION_ACYL_COA_SYNTHESIS	CPT1A CPT1B	2.00e-03	11	87	2	M47626
Pathway	BIOCARTA_PLCE_PATHWAY	PRKAR1A PRKAR1B	2.00e-03	11	87	2	MM1455
Pathway	BIOCARTA_CFTR_PATHWAY	PRKAR1A PRKAR1B	2.00e-03	11	87	2	M12399
Pathway	BIOCARTA_AGPCR_PATHWAY	PRKAR1A PRKAR1B	2.00e-03	11	87	2	M19829
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_CROSSTALK_BETWEEN_EXTRINSIC_AND_INTRINSIC_APOPTOTIC_PATHWAYS	CASP3 BAX	2.00e-03	11	87	2	M47693
Pathway	KEGG_APOPTOSIS	CASP3 BAX PRKAR1A PRKAR1B	2.04e-03	87	87	4	M8492
Pathway	REACTOME_DAG_AND_IP3_SIGNALING	ADCY3 PRKAR1A PRKAR1B	2.04e-03	41	87	3	M512
Pathway	REACTOME_ADORA2B_MEDIATED_ANTI_INFLAMMATORY_CYTOKINES_PRODUCTION	ADCY3 PRKAR1A PRKAR1B	2.34e-03	43	87	3	M29837
Pathway	REACTOME_VASOPRESSIN_REGULATES_RENAL_WATER_HOMEOSTASIS_VIA_AQUAPORINS	ADCY3 PRKAR1A PRKAR1B	2.34e-03	43	87	3	M933
Pathway	BIOCARTA_CARM1_PATHWAY	PRKAR1A PRKAR1B	2.39e-03	12	87	2	M7968
Pathway	REACTOME_CREB1_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_ADENYLATE_CYCLASE	PRKAR1A PRKAR1B	2.39e-03	12	87	2	M27363
Pathway	REACTOME_ALK_MUTANTS_BIND_TKIS	BIRC6 PRKAR1A	2.39e-03	12	87	2	M42522
Pathway	WP_ENTEROHEPATIC_CIRCULATION_OF_BILE_ACIDS	ABCC3 SLC10A1	2.39e-03	12	87	2	M48096
Pathway	BIOCARTA_DREAM_PATHWAY	PRKAR1A PRKAR1B	2.39e-03	12	87	2	MM1475
Pathway	KEGG_MEDICUS_REFERENCE_CA2_ENTRY_LIGAND_GATED_CA2_CHANNEL	P2RX4 P2RX7	2.39e-03	12	87	2	M47953
Pubmed	Characterization of the human ABC superfamily: isolation and mapping of 21 new genes using the expressed sequence tags database.	ABCC3 ABCA4 ABCA10 ABCA9 ABCA6 ABCA5	7.76e-11	22	114	6	8894702
Pubmed	The human ATP-binding cassette (ABC) transporter superfamily.	ABCA10 ABCA9 ABCA6 ABCA5	2.26e-08	10	114	4	11435397
Pubmed	Evolutionary analysis of a cluster of ATP-binding cassette (ABC) genes.	ABCA9 ABCA6 ABCA5	3.41e-07	5	114	3	12532264
Pubmed	The p53 tumor suppressor causes congenital malformations in Rpl24-deficient mice and promotes their survival.	CASP3 BAX CUL9 CCNG1	4.09e-07	19	114	4	19273598
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SH3TC2 DYNC2H1 ATP13A1 DGKD CLSTN1 BIRC6 PRX DNAH17 ZNF616 REXO1L1P NUP160	7.20e-07	493	114	11	15368895
Pubmed	A hierarchical NGF signaling cascade controls Ret-dependent and Ret-independent events during development of nonpeptidergic DRG neurons.	CASP3 BAX RUNX1 TRPM8	1.11e-06	24	114	4	17553423
Pubmed	The Birc6 (Bruce) gene regulates p53 and the mitochondrial pathway of apoptosis and is essential for mouse embryonic development.	CASP3 BAX BIRC6	1.19e-06	7	114	3	15640352
Pubmed	Microglia proliferation is controlled by P2X7 receptors in a Pannexin-1-independent manner during early embryonic spinal cord invasion.	CASP3 P2RX4 P2RX7	4.05e-06	10	114	3	22915101
Pubmed	Viral genetic determinants of nonprogressive HIV type 1 subtype C infection in antiretroviral drug-naive children.	CASP3 PRKAR1A PRKAR1B	9.58e-06	13	114	3	19895210
Pubmed	Variants within the muscle and liver isoforms of the carnitine palmitoyltransferase I (CPT1) gene interact with fat intake to modulate indices of obesity in French-Canadians.	CPT1A CPT1B	1.07e-05	2	114	2	17089095
Pubmed	Activation of caspase-3 apoptotic pathways in skeletal muscle fibers in laminin alpha2-deficient mice.	CASP3 LAMA2	1.07e-05	2	114	2	10381357
Pubmed	Lipopolysaccharide-induced apoptosis in a murine intestinal endocrine cell line by modulation of Bcl-2, Bax and caspase-3.	CASP3 BAX	1.07e-05	2	114	2	24145669
Pubmed	P2X7/P2X4 Receptors Mediate Proliferation and Migration of Retinal Microglia in Experimental Glaucoma in Mice.	P2RX4 P2RX7	1.07e-05	2	114	2	35254644
Pubmed	Promoter for the regulatory type I beta subunit of the 3',5'-cyclic adenosine monophosphate-dependent protein kinase directs transgene expression in the central nervous system.	PRKAR1A PRKAR1B	1.07e-05	2	114	2	1448119
Pubmed	Changes of Bcl-2, Bax and Caspase-3 expression in the dermal microvascular endothelial cells and the epidermal layers of the eschar (tache noire) in patients with Mediterranean spotted fever.	CASP3 BAX	1.07e-05	2	114	2	23907941
Pubmed	No differences in caspase-3 and Bax expression in atrophic-erosive vs. reticular oral lichen planus.	CASP3 BAX	1.07e-05	2	114	2	18211414
Pubmed	Distinct contributions by ionotropic purinoceptor subtypes to ATP-evoked calcium signals in mouse parotid acinar cells.	P2RX4 P2RX7	1.07e-05	2	114	2	22451435
Pubmed	A rare functional haplotype of the P2RX4 and P2RX7 genes leads to loss of innate phagocytosis and confers increased risk of age-related macular degeneration.	P2RX4 P2RX7	1.07e-05	2	114	2	23303206
Pubmed	MAPK signaling pathways regulate mitochondrial-mediated apoptosis induced by isoorientin in human hepatoblastoma cancer cells.	CASP3 BAX	1.07e-05	2	114	2	23220614
Pubmed	Functional interactions between P2X4 and P2X7 receptors from mouse salivary epithelia.	P2RX4 P2RX7	1.07e-05	2	114	2	19403602
Pubmed	P2X4 and P2X7 are essential players in basal T cell activity and Ca2+ signaling milliseconds after T cell activation.	P2RX4 P2RX7	1.07e-05	2	114	2	35119925
Pubmed	Involvement of P2X4 receptor in P2X7 receptor-dependent cell death of mouse macrophages.	P2RX4 P2RX7	1.07e-05	2	114	2	22349510
Pubmed	Triggering regeneration and tackling apoptosis: a combinatorial approach to treating congenital muscular dystrophy type 1 A.	LAMA2 BAX	1.07e-05	2	114	2	23773998
Pubmed	The Ca(2+) channel inhibitor 2-APB reverses β-amyloid-induced LTP deficit in hippocampus by blocking BAX and caspase-3 hyperactivation.	CASP3 BAX	1.07e-05	2	114	2	25521332
Pubmed	P2X currents in peritoneal macrophages of wild type and P2X4 -/- mice.	P2RX4 P2RX7	1.07e-05	2	114	2	17825926
Pubmed	Fine chromosome mapping of the genes for human liver and muscle carnitine palmitoyltransferase I (CPT1A and CPT1B).	CPT1A CPT1B	1.07e-05	2	114	2	9070950
Pubmed	The ATP Receptors P2X7 and P2X4 Modulate High Glucose and Palmitate-Induced Inflammatory Responses in Endothelial Cells.	P2RX4 P2RX7	1.07e-05	2	114	2	25938443
Pubmed	Olfactory neurons in bax knockout mice are protected from bulbectomy-induced apoptosis.	CASP3 BAX	1.07e-05	2	114	2	14561915
Pubmed	Recombination adenovirus-mediated human lactoferrin cDNA inhibits the growth of human MCF-7 breast cancer cells.	CASP3 BAX	1.07e-05	2	114	2	22309278
Pubmed	Role of purinergic receptors in hepatobiliary carcinoma in Pakistani population: an approach towards proinflammatory role of P2X4 and P2X7 receptors.	P2RX4 P2RX7	1.07e-05	2	114	2	31401785
Pubmed	Reversible inhibition of Chlamydia trachomatis infection in epithelial cells due to stimulation of P2X(4) receptors.	P2RX4 P2RX7	1.07e-05	2	114	2	22988022
Pubmed	Purinergic receptors P2RX4 and P2RX7 in familial multiple sclerosis.	P2RX4 P2RX7	1.07e-05	2	114	2	28326637
Pubmed	Atypical P2X receptor pharmacology in two human osteoblast-like cell lines.	P2RX4 P2RX7	1.07e-05	2	114	2	19226284
Pubmed	Deficiency of caspase-3 in MCF7 cells blocks Bax-mediated nuclear fragmentation but not cell death.	CASP3 BAX	1.07e-05	2	114	2	11350920
Pubmed	P2X7R and P2X4R expression of mice submandibular gland in high-fat diet/streptozotocin-induced type 2 diabetes.	P2RX4 P2RX7	1.07e-05	2	114	2	38740782
Pubmed	Differential regulation of microglial P2X4 and P2X7 ATP receptors following LPS-induced activation.	P2RX4 P2RX7	1.07e-05	2	114	2	17675190
Pubmed	[Effect of grape procyanidins on expressions of Caspase-3 and Bax in ethanol-induced liver injury in mice].	CASP3 BAX	1.07e-05	2	114	2	21434306
Pubmed	Analysis of assembly and trafficking of native P2X4 and P2X7 receptor complexes in rodent immune cells.	P2RX4 P2RX7	1.07e-05	2	114	2	19304656
Pubmed	Expression and regulation of carnitine palmitoyltransferase-Ialpha and -Ibeta genes.	CPT1A CPT1B	1.07e-05	2	114	2	10408760
Pubmed	P2X4 receptor regulates P2X7 receptor-dependent IL-1β and IL-18 release in mouse bone marrow-derived dendritic cells.	P2RX4 P2RX7	1.07e-05	2	114	2	23428419
Pubmed	Cleavage of huntingtin by apopain, a proapoptotic cysteine protease, is modulated by the polyglutamine tract.	CASP3 HTT	1.07e-05	2	114	2	8696339
Pubmed	Evidence for functional P2X4/P2X7 heteromeric receptors.	P2RX4 P2RX7	1.07e-05	2	114	2	17785580
Pubmed	T-2 toxin induces apoptosis via the Bax-dependent caspase-3 activation in mouse primary Leydig cells.	CASP3 BAX	1.07e-05	2	114	2	28697680
Pubmed	Inhibition of apoptosis improves outcome in a model of congenital muscular dystrophy.	LAMA2 BAX	1.07e-05	2	114	2	15578095
Pubmed	Enhanced oligodendrocyte survival after spinal cord injury in Bax-deficient mice and mice with delayed Wallerian degeneration.	CASP3 BAX	1.07e-05	2	114	2	14507967
Pubmed	Different localization of P2X4 and P2X7 receptors in native mouse lung - lack of evidence for a direct P2X4-P2X7 receptor interaction.	P2RX4 P2RX7	1.07e-05	2	114	2	38953020
Pubmed	Huntingtin inhibits caspase-3 activation.	CASP3 HTT	1.07e-05	2	114	2	17124493
Pubmed	Time-resolved role of P2X4 and P2X7 during CD8+ T cell activation.	P2RX4 P2RX7	1.07e-05	2	114	2	38426095
Pubmed	Novel isozymes of cAMP-dependent protein kinase exist in human cells due to formation of RI alpha-RI beta heterodimeric complexes.	PRKAR1A PRKAR1B	1.07e-05	2	114	2	8407966
Pubmed	Extracellular ATP Augments Antigen-Induced Murine Mast Cell Degranulation and Allergic Responses via P2X4 Receptor Activation.	P2RX4 P2RX7	1.07e-05	2	114	2	32358018
Pubmed	Deleterious variants in X-linked CFAP47 induce asthenoteratozoospermia and primary male infertility.	CFAP47 CFAP65	1.07e-05	2	114	2	33472045
Pubmed	Molecular diagnosis of putative Stargardt disease by capture next generation sequencing.	ABCA4 PROM1	1.07e-05	2	114	2	24763286
Pubmed	Bax-dependent caspase-3 activation is a key determinant in p53-induced apoptosis in neurons.	CASP3 BAX	1.07e-05	2	114	2	10479688
Pubmed	Inhibition of carnitine palmitoyltransferase I augments sphingolipid synthesis and palmitate-induced apoptosis.	CPT1A CPT1B	1.07e-05	2	114	2	9013572
Pubmed	Regulation of P2X7-dependent inflammatory functions by P2X4 receptor in mouse macrophages.	P2RX4 P2RX7	1.07e-05	2	114	2	22405772
Pubmed	Inactivation of Mdm2 restores apoptosis proficiency of cooperativity mutant p53 in vivo.	CASP3 BAX CCNG1	1.22e-05	14	114	3	31749402
Pubmed	The N6-methyladenosine-mediated lncRNA WEE2-AS1 promotes glioblastoma progression by stabilizing RPN2.	MASP1 ABCA4 BAX NIBAN2 HUWE1 CPT1A PRKAR1A NUP160	1.24e-05	325	114	8	36168628
Pubmed	RBM19 is essential for preimplantation development in the mouse.	CASP3 BAX CCNG1	1.52e-05	15	114	3	19087264
Pubmed	Dynamic regulation of the expression of neurotrophin receptors by Runx3.	CASP3 BAX RUNX1	1.52e-05	15	114	3	18385258
Pubmed	cAMP-dependent protein kinase: framework for a diverse family of regulatory enzymes.	ADCY3 PRKAR1A PRKAR1B	1.52e-05	15	114	3	2165385
Pubmed	Synergism between p53 and Mcl-1 in protecting from hepatic injury, fibrosis and cancer.	CASP3 BAX CCNG1	1.86e-05	16	114	3	21146511
Pubmed	Bax cleavage implicates caspase-dependent H2O2-induced apoptosis of hepatocytes.	CASP3 BAX	3.19e-05	3	114	2	12579342
Pubmed	Groucho/TLE/R-esp proteins associate with the nuclear matrix and repress RUNX (CBF(alpha)/AML/PEBP2(alpha)) dependent activation of tissue-specific gene transcription.	RUNX1 TLE2	3.19e-05	3	114	2	10825294
Pubmed	Association of polymorphisms in P2RX7 and CaMKKb with anxiety disorders.	P2RX4 P2RX7	3.19e-05	3	114	2	17197037
Pubmed	Effects of taspine on proliferation and apoptosis by regulating caspase-3 expression and the ratio of Bax/Bcl-2 in A431 cells.	CASP3 BAX	3.19e-05	3	114	2	20683843
Pubmed	E2F is involved in radioresistance of carbon ion induced apoptosis via Bax/caspase 3 signal pathway in human hepatoma cell.	CASP3 BAX	3.19e-05	3	114	2	28500630
Pubmed	Synergistic Cytokine Production by ATP and PGE2 via P2X4 and EP3 Receptors in Mouse Bone-Marrow-Derived Mast Cells.	P2RX4 P2RX7	3.19e-05	3	114	2	35203267
Pubmed	Nonapoptotic function of BAD and BAX in long-term depression of synaptic transmission.	CASP3 BAX	3.19e-05	3	114	2	21609830
Pubmed	miR-98 and its host gene Huwe1 target Caspase-3 in Silica nanoparticles-treated male germ cells.	CASP3 HUWE1	3.19e-05	3	114	2	26263183
Pubmed	Generation and characterization of Ccdc28b mutant mice links the Bardet-Biedl associated gene with mild social behavioral phenotypes.	MCHR1 ADCY3	3.19e-05	3	114	2	35653384
Pubmed	Ku70 regulates Bax-mediated pathogenesis in laminin-alpha2-deficient human muscle cells and mouse models of congenital muscular dystrophy.	LAMA2 BAX	3.19e-05	3	114	2	19692349
Pubmed	Apollon gene silencing induces apoptosis in breast cancer cells through p53 stabilisation and caspase-3 activation.	CASP3 BIRC6	3.19e-05	3	114	2	19223905
Pubmed	Genomic structure of and a cardiac promoter for the mouse carnitine palmitoyltransferase II gene.	CPT1A CPT1B	3.19e-05	3	114	2	8307575
Pubmed	[Apoptosis-inducing effect of clostridium difficile toxin A on K562 cells and its mechanism].	CASP3 BAX	3.19e-05	3	114	2	21729540
Pubmed	Developmental patterns of caspase-3, bax and bcl-2 proteins expression in the human spinal ganglia.	CASP3 BAX	3.19e-05	3	114	2	18415689
Pubmed	Involvement of TRPV3 and TRPM8 ion channel proteins in induction of mammalian cold-inducible proteins.	TRPM8 TRPV3	3.19e-05	3	114	2	29175331
Pubmed	Macrophage P2X4 receptors augment bacterial killing and protect against sepsis.	P2RX4 P2RX7	3.19e-05	3	114	2	29875325
Pubmed	Functional evidence for the expression of P2X1, P2X4 and P2X7 receptors in human lung mast cells.	P2RX4 P2RX7	3.19e-05	3	114	2	19552691
Pubmed	Bax limits adult neural stem cell persistence through caspase and IP3 receptor activation.	CASP3 BAX	3.19e-05	3	114	2	15947791
Pubmed	Sepia ink oligopeptide induces apoptosis in prostate cancer cell lines via caspase-3 activation and elevation of Bax/Bcl-2 ratio.	CASP3 BAX	3.19e-05	3	114	2	23170075
Pubmed	Characterization of the molecular interaction between caveolin-1 and the P2X receptors 4 and 7 in E10 mouse lung alveolar epithelial cells.	P2RX4 P2RX7	3.19e-05	3	114	2	18407780
Pubmed	Epigallocatechin-3-gallate induces apoptosis in estrogen receptor-negative human breast carcinoma cells via modulation in protein expression of p53 and Bax and caspase-3 activation.	CASP3 BAX	3.19e-05	3	114	2	15657356
Pubmed	HIV-1 gp120- and gp160-induced apoptosis in cultured endothelial cells is mediated by caspases.	CASP3 BAX	3.19e-05	3	114	2	10942389
Pubmed	Involvement of P2X4 and P2Y12 receptors in ATP-induced microglial chemotaxis.	P2RX4 P2RX7	3.19e-05	3	114	2	17299767
Pubmed	Increased expression of GGN promotes tumorigenesis in bladder cancer and is correlated with poor prognosis.	GGN CASP3	3.19e-05	3	114	2	29412153
Pubmed	Porphyromonas gingivalis induced inflammatory responses and promoted apoptosis in lung epithelial cells infected with H1N1 via the Bcl‑2/Bax/Caspase‑3 signaling pathway.	CASP3 BAX	3.19e-05	3	114	2	29750299
Pubmed	Knockdown of apoptosis repressor with caspase recruitment domain (ARC) increases the sensitivity of human glioma cell line U251MG to VM-26.	CASP3 BAX	3.19e-05	3	114	2	22949938
Pubmed	Immunohistochemical evidence of P2X7R, P2X4R and CaMKK2 in pyramidal neurons of frontal cortex does not align with Alzheimer's disease.	P2RX4 P2RX7	3.19e-05	3	114	2	33838119
Pubmed	Bax, caspase-2, and caspase-3 are required for ovarian follicle loss caused by 4-vinylcyclohexene diepoxide exposure of female mice in vivo.	CASP3 BAX	3.19e-05	3	114	2	12488331
Pubmed	A novel synthetic analog of Militarin, MA-1 induces mitochondrial dependent apoptosis by ROS generation in human lung cancer cells.	CASP3 BAX	3.19e-05	3	114	2	24161344
Pubmed	Exclusion of catalytic and regulatory subunits of cAMP-dependent protein kinase as candidate genes for the defect causing cystic fibrosis.	PRKAR1A PRKAR1B	3.19e-05	3	114	2	3479018
Pubmed	Immunohistochemical localization of caspase-3, caspase-9 and Bax in U87 glioblastoma xenografts.	CASP3 BAX	3.19e-05	3	114	2	18814044
Pubmed	Ambulatory blood pressure is associated with polymorphic variation in P2X receptor genes.	P2RX4 P2RX7	3.19e-05	3	114	2	18852390
Pubmed	Cytosolic accumulation of HSP60 during apoptosis with or without apparent mitochondrial release: evidence that its pro-apoptotic or pro-survival functions involve differential interactions with caspase-3.	CASP3 BAX	3.19e-05	3	114	2	17823127
Pubmed	Role of Bcl-2 family proteins and caspase-3 in sanguinarine-induced bimodal cell death.	CASP3 BAX	3.19e-05	3	114	2	11787859
Pubmed	Expression in skin biopsies supports genetic evidence linking CAMKK2, P2X7R and P2X4R with HIV-associated sensory neuropathy.	P2RX4 P2RX7	3.19e-05	3	114	2	37166584
Pubmed	Molecular analysis of human solute carrier SLC26 anion transporter disease-causing mutations using 3-dimensional homology modeling.	SLC26A2 SLC26A4	3.19e-05	3	114	2	28941661
Pubmed	In situ immunodetection of activated caspase-3 in apoptotic neurons in the developing nervous system.	CASP3 BAX	3.19e-05	3	114	2	9894607
Pubmed	Selenium compounds induced ROS-dependent apoptosis in myelodysplasia cells.	CASP3 BAX	3.19e-05	3	114	2	23900644
Pubmed	A Flow Cytometry-Based Approach for the Isolation and Characterization of Neural Stem Cell Primary Cilia.	ADCY3 PROM1	3.19e-05	3	114	2	30692915
Cytoband	Ensembl 112 genes in cytogenetic band chr17q24	ABCA10 ABCA9 ABCA6 ABCA5 PRKAR1A	4.88e-06	98	114	5	chr17q24
GeneFamily	ATP binding cassette subfamily A	ABCA4 ABCA10 ABCA9 ABCA6 ABCA5	1.82e-09	14	73	5	805
GeneFamily	Solute carriers	SLC29A3 SLC2A8 SLC26A2 SLC26A4 SLC6A9 SLC39A12 SLC10A1 SLCO1C1	1.88e-04	395	73	8	752
GeneFamily	Purinergic receptors P2X	P2RX4 P2RX7	3.33e-04	7	73	2	214
ToppCell	Bronchial-NucSeq-Stromal-Fibroblastic-Fibro_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CASS4 LAMA2 ABCA10 ABCA9 HMCN1 ABCA6 LRFN5 PHACTR3	4.87e-08	200	114	8	e8462395fee0a532d1e7ec7f1795f28c42af6541
ToppCell	Parenchymal-NucSeq-Stromal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CASS4 LAMA2 ABCA10 ABCA9 HMCN1 ABCA6 LRFN5 PHACTR3	4.87e-08	200	114	8	cf433f9b43d7db07acaf70e060f8f77c974e72f3
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CASS4 LAMA2 ABCA10 ABCA9 HMCN1 ABCA6 LRFN5 PHACTR3	4.87e-08	200	114	8	311fab076f2ceb258e3970eb21e39344b894042a
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-high_Fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 ABCA10 ABCA9 CEMIP ABCA6 LRFN5 TLE2	1.81e-07	159	114	7	e812cbde59188924c6277c3feadf1a9592fa62a4
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-high_Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 ABCA10 ABCA9 CEMIP ABCA6 LRFN5 TLE2	1.81e-07	159	114	7	2607b562903228274fbd96168ba826782fab0b53
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CASS4 LAMA2 ABCA10 HMCN1 ABCA6 LRFN5 PHACTR3	4.35e-07	181	114	7	9ede19228ba5c0668a9c06c915510b95585216ef
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-4\|TCGA-Pancreas / Sample_Type by Project: Shred V9	SLC26A2 LAMA2 ABCA9 GHSR HMCN1 ABCA6 LRFN5	4.86e-07	184	114	7	67164bb6bcae7322cb89b585c7aa10bce35b0ecd
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	LAMA2 ABCA10 ABCA9 HMCN1 ABCA6 LRFN5 PHACTR3	6.24e-07	191	114	7	6688cee34beee4f151ac17fccbc9c26a9aad72e1
ToppCell	Tracheal-NucSeq-Stromal-Peri/Epineurial_-NAF_endoneurial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	LAMA2 ABCA10 ABCA9 SLCO1C1 ABCA6 HSD17B11 LRRC18	6.69e-07	193	114	7	549a0b750c860b615aff767ad04c9a9d20f802f0
ToppCell	Adult-Mesenchymal-matrix_fibroblast_1_cell-D231\|Adult / Lineage, Cell type, age group and donor	CASS4 LAMA2 ABCA9 CEMIP HMCN1 ABCA6 PHACTR3	6.69e-07	193	114	7	ef2f456c094e6e3c6ee81e0668c953cb8d0e1c0a
ToppCell	COVID-19-Fibroblasts-Alveolar_FB\|COVID-19 / group, cell type (main and fine annotations)	LAMA2 ABCA10 ABCA9 CEMIP HMCN1 ABCA6 PHACTR3	7.17e-07	195	114	7	603050beeb33c331d4b2e3fa46cae3f3e0e4bdc7
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DYNC2H1 ABCA10 ABCA9 SPPL2A HMCN1 ABCA6 ABCA5	7.17e-07	195	114	7	a38d9dc6192aea673d96fda6b25e81223fda3abf
ToppCell	Adult-Mesenchymal\|Adult / Lineage, Cell type, age group and donor	LAMA2 ABCA10 ABCA9 HMCN1 ABCA6 LRFN5 PHACTR3	7.95e-07	198	114	7	26e55b409db2a1637c95fae7c54b0abea1ef550c
ToppCell	Parenchyma_Control_(B.)-Stromal-TX-Fibroblasts-1\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	CASS4 LAMA2 ABCA9 CEMIP HMCN1 ABCA6 PHACTR3	8.50e-07	200	114	7	aa1a35dcca3b799241eef4237f6eb94660e019f0
ToppCell	Lung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-1\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	CASS4 LAMA2 ABCA9 CEMIP HMCN1 ABCA6 PHACTR3	8.50e-07	200	114	7	a510deaada669e690329183e18df02870bd204b3
ToppCell	Bronchial-NucSeq-Stromal-Fibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	LAMA2 ABCA10 ABCA9 HMCN1 ABCA6 LRFN5 PHACTR3	8.50e-07	200	114	7	cae972324d1dfea6efeaf6013f265c7c6bb48db4
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic-Fibro_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CASS4 LAMA2 ABCA9 HMCN1 ABCA6 LRFN5 PHACTR3	8.50e-07	200	114	7	34f52003988ce6329d8deeee1ab875fa77e01e9d
ToppCell	Lung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-1-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CASS4 LAMA2 ABCA9 CEMIP HMCN1 ABCA6 PHACTR3	8.50e-07	200	114	7	dd4228cbed8a4395166a6332e08d44d88bebe3b9
ToppCell	LPS-antiTNF-Lymphocytic_NKT-T_cells-Neutrophils\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BCKDK NUF2 CPT1A CEMIP CCNG1 LIG4	2.76e-06	153	114	6	c4dcdcaa672929c1da870e9fb8ada1bb030ad12f
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	C1orf87 LAMA2 ABCA10 ABCA9 SLCO1C1 ABCA6	3.98e-06	163	114	6	bbc078761c5043af13d9a6fcf3145a3e300bae5e
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	C1orf87 LAMA2 ABCA10 ABCA9 SLCO1C1 ABCA6	3.98e-06	163	114	6	8e32b6431e1862572663aa6ddc4ea299c6acc8a6
ToppCell	facs\|World / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLSTN1 BIRC6 ABCA9 SLC10A1 RRN3 IL6R	5.99e-06	175	114	6	53e96956019f984decc1c81376ebc88fbf3c4d40
ToppCell	Adult-Mesenchymal-matrix_fibroblast_2_cell-D231\|Adult / Lineage, Cell type, age group and donor	MASP1 LAMA2 ABCA10 ABCA9 ABCA6 LRFN5	8.22e-06	185	114	6	fb6bd7e849ecf4ed9cd9c4e2a946a2d12d62f804
ToppCell	COVID-19-Fibroblasts-Adventitial_FB\|COVID-19 / group, cell type (main and fine annotations)	LAMA2 ABCA10 ABCA9 CEMIP ABCA6 LRFN5	8.22e-06	185	114	6	a5aebf2b9b05b550d021272731d68af9a6b1229d
ToppCell	5'-Adult-Appendix-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CTSF LAMA2 DLK1 ABCA10 ABCA9 ABCA6	8.48e-06	186	114	6	7582b5154d8e5a4434817b5ab77a10b789ea2288
ToppCell	Adult-Mesenchymal-matrix_fibroblast_1_cell-D175\|Adult / Lineage, Cell type, age group and donor	CASS4 LAMA2 CEMIP HMCN1 LRFN5 PHACTR3	8.74e-06	187	114	6	e15d2967aac248da3517bc2c7d1beaa1d5a0aa7f
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DYNC2H1 ABCA10 ABCA9 HMCN1 ABCA6 ABCA5	8.74e-06	187	114	6	f124d2c699b717b7c02a1a70493f515b83dc2f4c
ToppCell	Control-Fibroblasts-Other_FB\|Control / group, cell type (main and fine annotations)	LAMA2 ABCA10 ABCA9 HMCN1 ABCA6 LRFN5	8.74e-06	187	114	6	bd3739c4a52aa1ba5deffd778e113a9800f7e158
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 ABCA10 ABCA9 CEMIP ABCA6 LRFN5	9.29e-06	189	114	6	71397e993a77d70b2eeede240bdfc7660b558987
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 ABCA10 ABCA9 CEMIP ABCA6 LRFN5	9.29e-06	189	114	6	4eea4759520c312bd17a681034d8074e47093d2b
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DYNC2H1 PLPPR1 ABCA10 SPPL2A HMCN1 ABCA5	9.29e-06	189	114	6	977a813e5d7a5a561c1fced2bbf21c20056b88d8
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DYNC2H1 ABCA10 ABCA9 HMCN1 ABCA6 ABCA5	9.29e-06	189	114	6	e32172ad09e93f6ac6ea2b92145b2b73003f7970
ToppCell	Adult-Mesenchymal-matrix_fibroblast_2_cell-D175\|Adult / Lineage, Cell type, age group and donor	LAMA2 ABCA10 ADCY3 ABCA9 ABCA6 LRFN5	9.57e-06	190	114	6	7dcca3469f3a3b70db0420cb94f7765f39492f06
ToppCell	Control-Fibroblasts\|Control / group, cell type (main and fine annotations)	LAMA2 ABCA10 ABCA9 HMCN1 ABCA6 LRFN5	9.57e-06	190	114	6	3a42a9b98d954685d38a741f44545898d0e3e9ce
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DYNC2H1 PLPPR1 ABCA10 SPPL2A HMCN1 ABCA5	9.57e-06	190	114	6	e252e925600e6457fa6e362a55217f4cffa75cdb
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CTSF LAMA2 DLK1 ABCA10 ABCA9 ABCA6	9.86e-06	191	114	6	4e4488380379ed29d7898bae4e24221e7c67eb9d
ToppCell	RV-01._Fibroblast_I\|World / Chamber and Cluster_Paper	DYNC2H1 LAMA2 ABCA10 ABCA9 ABCA6 LRFN5	9.86e-06	191	114	6	70c067c54084bfb02c29bab085f4defd477194fb
ToppCell	RV-01._Fibroblast_I\|RV / Chamber and Cluster_Paper	DYNC2H1 LAMA2 ABCA10 ABCA9 ABCA6 LRFN5	1.02e-05	192	114	6	356160b113c3305a61ceeaff33ce3c9da0be2878
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	LAMA2 ABCA10 ABCA9 HMCN1 ABCA6 PHACTR3	1.02e-05	192	114	6	99ce9e3c4c50cf64ebb62145f2b5420efa0db309
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 ADCY3 ABCA9 FAM153A ABCA6 LRFN5	1.05e-05	193	114	6	09a9ab029f01234459a88e3e994fe90ef4cbb8c6
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CASS4 LAMA2 ABCA9 HMCN1 ABCA6 PHACTR3	1.05e-05	193	114	6	99525545552b371c86b18b6ea6f4897dc6e9a9ec
ToppCell	Mesenchymal-matrix_fibroblast_1_cell\|World / Lineage, Cell type, age group and donor	CASS4 LAMA2 HMCN1 ABCA6 LRFN5 PHACTR3	1.05e-05	193	114	6	acad568621ed677031797b8c2e34dafea798d681
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 ABCA10 ADCY3 ABCA9 ABCA6 LRFN5	1.08e-05	194	114	6	81713e0409e8be695ba5dfdc67a997b33435dd9e
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CASS4 LAMA2 ABCA9 ABCA6 PDE4DIP PHACTR3	1.08e-05	194	114	6	e93de9428c986b8943fc169258847c650cfab0e5
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CASS4 LAMA2 HMCN1 ABCA6 LRFN5 PHACTR3	1.08e-05	194	114	6	011e14d9ed1393275f892060e7708ffadcd0767f
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CASS4 LAMA2 CEMIP HMCN1 LRFN5 PHACTR3	1.08e-05	194	114	6	35f132cc38ac133be01834ed0946188aa0757eb4
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 ABCA10 ADCY3 ABCA9 ABCA6 LRFN5	1.08e-05	194	114	6	e03ba6caed59fa64d4d9b042593469d4a6a3dc10
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 ABCA10 ADCY3 ABCA9 ABCA6 LRFN5	1.08e-05	194	114	6	627cffe2d448e74fc5df92e74e5b922a73304137
ToppCell	Adult-Mesenchymal-matrix_fibroblast_1_cell\|Adult / Lineage, Cell type, age group and donor	CASS4 LAMA2 ABCA9 HMCN1 ABCA6 PHACTR3	1.11e-05	195	114	6	61c9e09fc84d1012e472185d70ad0a06cee30d6e
ToppCell	Children_(3_yrs)-Mesenchymal\|Children_(3_yrs) / Lineage, Cell type, age group and donor	LAMA2 ABCA10 ABCA9 HMCN1 ABCA6 LRFN5	1.14e-05	196	114	6	bc94909f9b2dc08a59eef1914148b69720569c8f
ToppCell	nucseq-Mesenchymal-Fibroblastic\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	LAMA2 ABCA10 ABCA9 HMCN1 ABCA6 LRFN5	1.14e-05	196	114	6	7d8505dac15fa59935ccf592afc54b04c4c6554f
ToppCell	RA-02._Fibroblast_II\|World / Chamber and Cluster_Paper	LAMA2 ABCA10 ABCA9 ABCA6 LRFN5 TLE2	1.14e-05	196	114	6	e8cbda03837f1f26470a9d93aa7fdaa04e08e38a
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic-Fibro_myofibroblast\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	LAMA2 ABCA10 ABCA9 HMCN1 ABCA6 LRFN5	1.18e-05	197	114	6	0dd71e399f253787fa546a7e90c5373180b89ffd
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 ABCA10 ADCY3 ABCA9 CEMIP ABCA6	1.18e-05	197	114	6	ae0435f4b4a9cdedb1c201fc56921048390097bf
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 ABCA10 ADCY3 ABCA9 CEMIP ABCA6	1.18e-05	197	114	6	37f6b6f2809b952382eaebb642b0aad6371f4251
ToppCell	COVID-19-Fibroblasts\|COVID-19 / group, cell type (main and fine annotations)	LAMA2 ABCA10 ABCA9 CEMIP HMCN1 ABCA6	1.18e-05	197	114	6	fb847f2277609c31fffcdf49517243ce0684facf
ToppCell	COVID-19-lung-Fibroblast\|COVID-19 / Disease (COVID-19 only), tissue and cell type	LAMA2 ABCA9 CEMIP HMCN1 ABCA6 LRFN5	1.21e-05	198	114	6	3ec01a55ade5e1627258cc3cfebb2c3207a4cb43
ToppCell	distal-mesenchymal-Adventitial_Fibroblast-2\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	MCHR1 LAMA2 ABCA10 ABCA9 ABCA6 LRFN5	1.21e-05	198	114	6	bfd720e2dae3b6b3dc2bf8b2096c554fd456e756
ToppCell	COVID-19-lung-Fibroblast\|lung / Disease (COVID-19 only), tissue and cell type	LAMA2 ABCA10 ABCA9 HMCN1 ABCA6 LRFN5	1.21e-05	198	114	6	df3de77216f5c5d6141ec44d01c56b942f611838
ToppCell	nucseq-Mesenchymal\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	LAMA2 ABCA10 ABCA9 HMCN1 ABCA6 LRFN5	1.21e-05	198	114	6	8f52243ca8b9ba68a75ae411506a3a6de258eb97
ToppCell	Mesenchymal\|World / Lineage, Cell type, age group and donor	LAMA2 ABCA10 ABCA9 HMCN1 ABCA6 LRFN5	1.25e-05	199	114	6	4bac110c2b3609f6ee5d0e3275da0824a6240270
ToppCell	moderate-Myeloid-Non-resident_Macrophage\|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	NIBAN2 RUNX1 SPPL2A P2RX4 P2RX7 PDE4DIP	1.25e-05	199	114	6	3895e367a33ac0316f96a64c07574de99684f4b7
ToppCell	Tracheal-NucSeq-Stromal-Peri/Epineurial_\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	LAMA2 ABCA10 ADCY3 ABCA9 SLCO1C1 ABCA6	1.25e-05	199	114	6	3835452e4848d7f7dd8651c17b746b271ef39688
ToppCell	distal-2-mesenchymal-Adventitial_Fibroblast\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	MCHR1 LAMA2 ABCA10 ABCA9 ABCA6 LRFN5	1.25e-05	199	114	6	97b475f9110ef7bb29d9cf2109b7e43177830f05
ToppCell	Tracheal-NucSeq-Stromal-Peri/Epineurial_-NAF_epineurial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	LAMA2 ABCA10 ADCY3 ABCA9 SLCO1C1 ABCA6	1.25e-05	199	114	6	9c2db0bb94cba71a3cc1827844da090e213e0258
ToppCell	Bronchial-NucSeq-Stromal-Fibroblastic-Fibro_adventitial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	LAMA2 ABCA10 ADCY3 ABCA9 ABCA6 LRFN5	1.28e-05	200	114	6	ad3fdcef895400f929f2ae12ff9bd85fd46adb3a
ToppCell	Bronchial-NucSeq-Stromal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	LAMA2 ABCA10 ABCA9 HMCN1 ABCA6 LRFN5	1.28e-05	200	114	6	389cc775c8419d90fb77cd794376d2160a7bf44e
ToppCell	Biopsy_Other_PF-Mesenchymal-PLIN2+_Fibroblasts\|Biopsy_Other_PF / Sample group, Lineage and Cell type	CTSF LAMA2 DLK1 ABCA10 ABCA9 ABCA6	1.28e-05	200	114	6	0aa316b71f195ecf17ee897e307f8928a755a637
ToppCell	cellseq2-Mesenchymal-Fibroblastic-Fibroblastic_1-AF2\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	LAMA2 ABCA10 ABCA9 HMCN1 ABCA6 LRFN5	1.28e-05	200	114	6	44317fbf4d1480a37b50ab2777bf1a3e4fc0c05f
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	LAMA2 ABCA10 ABCA9 HMCN1 ABCA6 LRFN5	1.28e-05	200	114	6	b4ccffdd79526c85e5273d27b668dbddcddba1ee
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic-Fibro_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	LAMA2 ABCA10 ABCA9 HMCN1 ABCA6 LRFN5	1.28e-05	200	114	6	3dd022e974fec7013ba18f333da63f58fbf2dd7c
ToppCell	cellseq2-Mesenchymal-Fibroblastic\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	LAMA2 ABCA10 ABCA9 HMCN1 ABCA6 LRFN5	1.28e-05	200	114	6	1c10597edd532bf172ca09870a937d35e2585081
ToppCell	cellseq2-Mesenchymal-Fibroblastic-Fibroblastic_1\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	LAMA2 ABCA10 ABCA9 HMCN1 ABCA6 LRFN5	1.28e-05	200	114	6	440dda48b09c6a8581b7ca634b0d67f1ecacf65e
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	LAMA2 ABCA10 ABCA9 HMCN1 ABCA6 LRFN5	1.28e-05	200	114	6	58b38f9a484ee94191091a0659ed62ebed2d4a14
ToppCell	Globus_pallidus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Inhibitory_Neuron.Gad1Gad2.Lamp5-Cplx3_(Substantia_Innominata_(SI))-\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	ABCA4 PCDHA5 C4orf54 TRPV3	2.98e-05	69	114	4	3074ec10315fb21048215125ec08b0d7922da3d9
ToppCell	Globus_pallidus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Inhibitory_Neuron.Gad1Gad2.Lamp5-Cplx3_(Substantia_Innominata_(SI))\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	ABCA4 PCDHA5 C4orf54 TRPV3	2.98e-05	69	114	4	f731d4500b139a8bef5c9185368509bf5a3791db
ToppCell	Globus_pallidus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Inhibitory_Neuron.Gad1Gad2.Lamp5-Cplx3_(Substantia_Innominata_(SI))--\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	ABCA4 PCDHA5 C4orf54 TRPV3	2.98e-05	69	114	4	40eb84fe36da5a4a82bd9b2d962b829e2c97a059
ToppCell	facs-Heart-Unknown-3m-Endothelial-endothelial_cell_of_coronary_artery\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA4 NUF2 ADAM28 MCTP2 PADI1	3.14e-05	141	114	5	4aa4b3476dc5abefbd348353cfe711cd5fe3d52f
ToppCell	facs-Heart-Unknown-3m-Endothelial-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA4 NUF2 ADAM28 MCTP2 PADI1	3.14e-05	141	114	5	e40c6f1b7fbaa46b3eaa55f1b37ef360b04370a8
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW10-OPC_related-Oligodendrocyte/OPC\|GW10 / Sample Type, Dataset, Time_group, and Cell type.	SLC26A2 LAMA2 RENBP HMCN1 P2RX7	4.36e-05	151	114	5	4533bccc996395f74b16af939ce79b6fe253c073
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW10-OPC_related\|GW10 / Sample Type, Dataset, Time_group, and Cell type.	SLC26A2 LAMA2 RENBP HMCN1 P2RX7	4.36e-05	151	114	5	edb2f59789c295838d2030b80c792cbea25eaa3d
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-high_Fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 ABCA9 SLC10A1 SLCO1C1 TLE2	6.09e-05	162	114	5	5f009b231f21861afee9cc0c569082e1135f929c
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-high_Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 ABCA9 SLC10A1 SLCO1C1 TLE2	6.09e-05	162	114	5	b936f8040dcd4db621ccded19237af8df7d0ed6e
ToppCell	Adult-Mesenchymal-chondrocyte-D231\|Adult / Lineage, Cell type, age group and donor	LAMA2 ABCA9 HMCN1 ABCA6 PHACTR3	6.45e-05	164	114	5	2ba57dce5f69a88f0d1e450b9780425e2d9ca7d4
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Hematologic-fibroblast\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC26A2 ARFGEF2 RUNX1 PRX P2RX7	7.03e-05	167	114	5	f5bffa77061baec0ba87bd688a047595f32534db
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 ABCA10 ABCA9 SLCO1C1 ABCA6	7.23e-05	168	114	5	d19a115365c5415e51c039718d7669de788fcf33
ToppCell	facs-Liver-Hepatocytes-24m-Myeloid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLSTN1 ADCY3 ABCA9 GLA PRKAR1B	7.23e-05	168	114	5	4ae9e9d93bcd6f4d5815e57fd5afa7a3398a0ec1
ToppCell	3'-GW_trimst-1-SmallIntestine-Epithelial-neuro-epithelial-L_cells_(PYY+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PLPPR1 ABCA10 CFAP65 ABCA6 ABCA5	7.23e-05	168	114	5	0f736d58cb0ff042fa3ce58e36bde37b6976f8fc
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 ABCA10 ABCA9 ABCA6 LRFN5	7.23e-05	168	114	5	4b2d29a7843bf45922038c093ca7ec0600756adc
ToppCell	facs-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLSTN1 ADCY3 ABCA9 GLA PRKAR1B	7.23e-05	168	114	5	04e168fe1d6f5f9e3d3bf9d7c13e800e3594868a
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 ABCA10 ABCA9 ABCA6 LRFN5	7.86e-05	171	114	5	5d31fc9b60329d4ae3c77e4ca679359d9314397d
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA10 ABCA9 HMCN1 ABCA6 ABCA5	8.30e-05	173	114	5	0c74bdb40e635d906fd180412c23bf7fed61621e
ToppCell	PND03-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ABCC3 SLC29A3 RUNX1 ABCA9 P2RX7	8.76e-05	175	114	5	53e6f1f8dd482dfa2539e068dacefbb6e08443bc
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MASP1 DPP10 B3GNT3 ABCA9 PROM1	9.00e-05	176	114	5	33323c97afe509147956b8df9f92ca6b0537e604
ToppCell	tumor_Lymph_Node_/_Brain-Fibroblasts-COL13A1+_matrix_FBs\|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass	MASP1 LAMA2 ABCA9 HMCN1 ABCA6	9.00e-05	176	114	5	510f9a14dc1c151d24d079e0cc004cdf4f86336c
ToppCell	356C-Fibroblasts-Fibroblast-C_(Myofibroblast)-\|356C / Donor, Lineage, Cell class and subclass (all cells)	MCHR1 GGN LAMA2 ABCA9 ABCA6	9.24e-05	177	114	5	cdfd2f0ee2f692271b1525e414b0f645cdadb1f6
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 ABCA10 ABCA9 ABCA6 LRFN5	9.24e-05	177	114	5	9ec7f1e64312d26d434b3312b58386715dbad644
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 ABCA10 ABCA9 ABCA6 LRFN5	9.24e-05	177	114	5	016277dfd59b1793fddaaadc2b3f41622d76ce3a
ToppCell	356C-Fibroblasts-Fibroblast-C_(Myofibroblast)\|356C / Donor, Lineage, Cell class and subclass (all cells)	MCHR1 GGN LAMA2 ABCA9 ABCA6	9.24e-05	177	114	5	db222faaecbe5600da39277243c4e7e764eb63c9
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 ADCY3 ABCA9 ABCA6 LRFN5	9.49e-05	178	114	5	d4ecb84e9b1f4ec49c519321156aa10f9bd34cce
Drug	docetaxel	ABCC3 ABCA4 CASP3 BAX ABCA10 ABCA9 ABCA6 ABCA5	3.13e-07	133	112	8	ctd:C067311
Drug	glibenclamide	ABCC3 ABCA4 DLK1 CPT1A CPT1B ABCA10 ADCY3 ABCA9 ABCA6 ABCA5 EHMT1 PRKAR1A	4.10e-07	382	112	12	CID000003488
Drug	Cephalothin	ABCC3 CASP3 BAX SLC10A1	7.26e-07	15	112	4	ctd:D002512
Drug	NSC606985	CASP3 BAX RUNX1	1.15e-06	5	112	3	CID000354677
Drug	GSK-3beta Inhibitor VIII; Up 200; 10uM; PC3; HT_HG-U133A	ABCC3 AVL9 B3GNT3 RUNX1 CPT1A RRN3 PDE4DIP PRKAR1B	4.60e-06	190	112	8	7070_UP
Drug	Bepridil hydrochloride [74764-40-2]; Up 200; 10uM; HL60; HT_HG-U133A	CASS4 LAMA2 RUNX1 PLPPR1 CLIP1 P2RX7 MCTP2 NUP160	5.37e-06	194	112	8	1274_UP
Drug	Lorglumide sodium salt [97964-56-2]; Up 200; 8.4uM; PC3; HT_HG-U133A	KAT6A BAX PCDHA5 HUWE1 RUNX1 P2RX7 DNAH17 MCTP2	6.01e-06	197	112	8	4658_UP
Drug	Laudanosine (R,S) [1699-51-0]; Up 200; 11.2uM; PC3; HT_HG-U133A	ABCC3 SH3TC2 AVL9 BAX LIG4 TLE2 PRKAR1B ZC3H7B	6.23e-06	198	112	8	7270_UP
Drug	Streptomycin sulfate [3810-74-0]; Up 200; 2.8uM; PC3; HT_HG-U133A	CTSF LAMA2 PCDHA5 RUNX1 CEMIP LIG4 SLC10A1 NUP160	6.23e-06	198	112	8	5837_UP
Drug	Niacin [59-67-6]; Up 200; 32.4uM; PC3; HT_HG-U133A	CASS4 RUNX1 SLC6A9 SLCO1C1 P2RX7 TLE2 DEPDC5 PADI1	6.23e-06	198	112	8	6702_UP
Drug	Tolazoline hydrochloride [59-97-2]; Up 200; 20.4uM; MCF7; HT_HG-U133A	RUNX1 PLPPR1 CEMIP TLE2 ZMIZ2 PDE4DIP TTI1 ZC3H7B	6.47e-06	199	112	8	1500_UP
Drug	Menthol	ABCC3 CASP3 TRPM8 TRPV3	1.04e-05	28	112	4	ctd:D008610
Drug	smilageninoside	CACNA1E CASP3 BAX	1.36e-05	10	112	3	CID000197391
Drug	nonyl acridine orange	CASP3 BAX P2RX7	1.36e-05	10	112	3	CID000115086
Drug	3,4,3',4'-tetrachlorobiphenyl	MASP1 CASP3 BAX HUWE1 CPT1A CLIP1 SLC6A9 PDE4DIP SARDH HSD17B11 IL6R	1.48e-05	453	112	11	ctd:C028451
Drug	Methamphetamine	MAGEA4 SLC29A3 OVCH2 KAT6A CASP3 BAX CUL9 RENBP NUF2 CLIP1 ADCY3 SLC6A9 PROM1 SLC39A12 SLC10A1 P2RX4 TLE2 ZMIZ2 PDE4DIP RNF225	1.50e-05	1401	112	20	ctd:D008694
Drug	sodium	ABCC3 SLC29A3 MCHR1 SLC2A8 SLC26A2 SLC26A4 HUWE1 CPT1B ADCY3 SLC6A9 LIG4 SLC10A1 ATP11B P2RX4 P2RX7 PRKAR1A	1.53e-05	944	112	16	CID000000923
Drug	physcione	ABCC3 BAX SLC10A1	1.86e-05	11	112	3	ctd:C008905
Drug	marchantin C	CASP3 BAX	2.40e-05	2	112	2	CID005319272
Drug	ethyl eicosapentaenoic acid	CASP3 BAX	2.40e-05	2	112	2	ctd:C495711
Drug	Hypoxanthine	CASP3 BAX HTT	2.47e-05	12	112	3	ctd:D019271
Drug	etomoxiryl-CoA	CPT1A CPT1B FASN	2.47e-05	12	112	3	CID003081714
Drug	DPCPX	CACNA1E ADCY3 GHSR P2RX4 P2RX7 PRKAR1A	2.49e-05	117	112	6	CID000001329
Drug	Diethylstilbestrol [56-53-1]; Up 200; 15uM; MCF7; HT_HG-U133A	BAX CUL9 PCDHA5 HUWE1 PDE4DIP CPLANE1 HSD17B11	2.99e-05	179	112	7	3895_UP
Drug	Tea	CASP3 BAX LIG4 FASN	3.60e-05	38	112	4	ctd:D013662
Drug	beta-hexachlorocyclohexane	ABCC3 CASP3 CPT1A FASN SLC10A1 ATP11B	3.78e-05	126	112	6	ctd:C023888
Drug	Securinine [5610-40-2]; Up 200; 18.4uM; MCF7; HT_HG-U133A	ABCC3 BAX RUNX1 CPT1B CEMIP ZC3H7B IL6R	3.82e-05	186	112	7	6831_UP
Drug	3-isoreserpine	ABCC3 ABCA4 ABCA10 ADCY3 ABCA9 ABCA6 ABCA5	4.37e-05	190	112	7	CID000005052
Drug	Diltiazem hydrochloride [33286-22-5]; Up 200; 8.8uM; PC3; HT_HG-U133A	RUNX1 CEMIP TLE2 PDE4DIP CPLANE1 MCTP2 PADI1	4.98e-05	194	112	7	6710_UP
Drug	Colchicine [64-86-8]; Down 200; 10uM; PC3; HT_HG-U133A	BAX CUL9 CPT1A CPT1B TLE2 PRKAR1B ZC3H7B	5.15e-05	195	112	7	4614_DN
Drug	Pivmecillinam hydrochloride [32887-03-9]; Down 200; 8.4uM; PC3; HT_HG-U133A	ABCC3 CUL9 DLK1 RUNX1 CLIP1 DUS2 NUP160	5.32e-05	196	112	7	7312_DN
Drug	Nicergoline; Up 200; 8.2uM; PC3; HT_HG-U133A	ABCC3 SH3TC2 BAX CPT1A DUS2 FICD PDE4DIP	5.32e-05	196	112	7	2058_UP
Drug	Ethotoin [86-35-1]; Down 200; 19.6uM; HL60; HT_HG-U133A	BAX ADCY3 LIG4 PDE4DIP DEPDC5 NUP160 IL6R	5.32e-05	196	112	7	2196_DN
Drug	Naringenine [480-41-1]; Up 200; 14.6uM; PC3; HT_HG-U133A	SLC26A4 RUNX1 ADAM28 LIG4 RRN3 PDE4DIP PADI1	5.32e-05	196	112	7	4597_UP
Drug	Ronidazole [7681-76-7]; Up 200; 20uM; PC3; HT_HG-U133A	CTSF SLC2A8 CUL9 CPT1A CEMIP SLC6A9 PDE4DIP	5.32e-05	196	112	7	7131_UP
Drug	(-)-Cinchonidine [485-71-2]; Up 200; 13.6uM; PC3; HT_HG-U133A	CASS4 BAX PCDHA5 B3GNT3 CPT1A ZC3H7B MCTP2	5.32e-05	196	112	7	5833_UP
Drug	genistein; Up 200; 10uM; MCF7; HT_HG-U133A	KAT6A BAX PCDHA5 RUNX1 CPT1B PDE4DIP ZC3H7B	5.32e-05	196	112	7	5232_UP
Drug	Liothyronine [6893-02-3]; Down 200; 6.2uM; PC3; HT_HG-U133A	BAX LIG4 ZMIZ2 PDE4DIP PRKAR1B CPLANE1 PADI1	5.32e-05	196	112	7	6602_DN
Drug	Gliclazide [21187-98-4]; Up 200; 12.4uM; HL60; HG-U133A	CTSF RUNX1 DUS2 SLC10A1 PDE4DIP ZC3H7B PADI1	5.32e-05	196	112	7	1720_UP
Drug	Canavanine sulfate monohydrate (L,+) [206996-57-8]; Down 200; 13.6uM; HL60; HT_HG-U133A	DYNC2H1 KAT6A RUNX1 CPT1A ADAM28 DUS2 NUP160	5.49e-05	197	112	7	2141_DN
Drug	Carisoprodol [78-44-4]; Up 200; 15.4uM; MCF7; HT_HG-U133A	CTSF CUL9 PCDHA5 RUNX1 PRKAR1B DEPDC5 HSD17B11	5.49e-05	197	112	7	4955_UP
Drug	Heliotrine [303-33-3]; Up 200; 12.8uM; PC3; HT_HG-U133A	ABCC3 KAT6A CPT1A ADAM28 CEMIP DNAH17 PDE4DIP	5.49e-05	197	112	7	3717_UP
Drug	Spironolactone [52-01-7]; Up 200; 9.6uM; MCF7; HT_HG-U133A	ABCC3 CTSF PCDHA5 B3GNT3 SLC6A9 PDE4DIP IL6R	5.49e-05	197	112	7	6255_UP
Drug	Debrisoquin sulfate [581-88-4]; Up 200; 9uM; PC3; HT_HG-U133A	CTSF BAX PCDHA5 RUNX1 SLC6A9 EHMT1 PADI1	5.49e-05	197	112	7	6688_UP
Drug	Seneciphylline [480-81-9]; Up 200; 12uM; MCF7; HT_HG-U133A	ABCC3 MASP1 CUL9 PLPPR1 TLE2 ZMIZ2 ZC3H7B	5.67e-05	198	112	7	2797_UP
Drug	Epicatechin-(-) [154-23-4]; Up 200; 13.8uM; PC3; HT_HG-U133A	RUNX1 SLC6A9 LIG4 P2RX7 DNAH17 NUP160 PADI1	5.67e-05	198	112	7	4594_UP
Drug	ICI 182,780; Up 200; 1uM; MCF7; HT_HG-U133A	ABCC3 CTSF DLK1 HUWE1 CPT1B TLE2 PDE4DIP	5.67e-05	198	112	7	6965_UP
Drug	ICI 182,780; Up 200; 1uM; MCF7; HT_HG-U133A_EA	SLC2A8 B3GNT3 CPT1B PRX SLCO1C1 PDE4DIP ZC3H7B	5.85e-05	199	112	7	985_UP
Drug	Iohexol [66108-95-0]; Up 200; 4.8uM; HL60; HT_HG-U133A	KAT6A ARFGEF2 HUWE1 RUNX1 SLC6A9 PDE4DIP ZC3H7B	5.85e-05	199	112	7	2461_UP
Drug	L(-)-vesamicol hydrochloride [112709-59-8]; Up 200; 13.6uM; MCF7; HT_HG-U133A	SLC26A2 CUL9 LIG4 SLC10A1 ZMIZ2 EHMT1 TRPM8	5.85e-05	199	112	7	5475_UP
Drug	Buserelin	ABCC3 CASP3 BAX	6.19e-05	16	112	3	ctd:D002064
Drug	spiroquinazoline	CASP3 BAX	7.17e-05	3	112	2	ctd:C088106
Drug	CDRI-97-78	CASP3 BAX	7.17e-05	3	112	2	ctd:C574493
Drug	xanthoangelol	CASP3 BAX	7.17e-05	3	112	2	ctd:C068244
Drug	xanthoangelol H	CASP3 BAX	7.17e-05	3	112	2	CID006479089
Drug	mirabijalone E	CASP3 BAX	7.17e-05	3	112	2	ctd:C000596409
Drug	ginkgolide K	CASP3 BAX	7.17e-05	3	112	2	ctd:C481151
Drug	Epirubicin	CASP3 BAX BIRC6 IL6R	8.41e-05	47	112	4	ctd:D015251
Drug	NSC640330	CASP3 CPT1A CPT1B FASN	9.14e-05	48	112	4	CID000005204
Drug	Methoxsalen	ABCC3 CASP3 BAX SLC10A1	9.14e-05	48	112	4	ctd:D008730
Drug	Beauvericin	CASP3 BAX DLK1	1.06e-04	19	112	3	CID000105014
Drug	substance B	CASP3 BAX GLA	1.24e-04	20	112	3	CID000433154
Drug	Dichlorodiphenyl Dichloroethylene	DPP10 CASP3 ARFGEF2 BAX RENBP RUNX1 CPT1A FASN	1.26e-04	302	112	8	ctd:D003633
Drug	AC1L1FF5	CASP3 DLK1 CPT1A CPT1B FASN GLA	1.28e-04	157	112	6	CID000003209
Drug	dioscin	CASP3 BAX CPT1A SLC10A1	1.35e-04	53	112	4	ctd:C019357
Drug	Lanthanoid Series Elements	CASP3 BAX	1.43e-04	4	112	2	ctd:D028581
Drug	ioversol	CASP3 BAX	1.43e-04	4	112	2	ctd:C054871
Drug	dehydroabietylamine acetate	CASP3 BAX	1.43e-04	4	112	2	CID000062034
Drug	2,6-difluoro-N-(1-(4-hydroxy-2-(trifluoromethyl)benzyl)-1H-pyrazol-3-yl)benzamide	CASP3 BAX	1.43e-04	4	112	2	ctd:C583716
Drug	macitentan	ABCC3 SLC10A1	1.43e-04	4	112	2	ctd:C533860
Drug	AC1LAY6G	CASP3 BAX	1.43e-04	4	112	2	CID000497896
Drug	Menthol	TRPM8 TRPV3	1.43e-04	4	112	2	DB00825
Drug	bornyl caffeate	CASP3 BAX	1.43e-04	4	112	2	ctd:C115950
Drug	NCI60_039755	CASP3 BAX	1.43e-04	4	112	2	CID000401428
Drug	astin B	CASP3 BAX	1.43e-04	4	112	2	ctd:C082414
Drug	cheliensisin A	CASP3 BAX	1.43e-04	4	112	2	CID005315815
Drug	glaucocalyxin A	CASP3 BAX	1.43e-04	4	112	2	ctd:C055124
Drug	foliol	CASP3 BAX	1.43e-04	4	112	2	CID000637194
Drug	rhodostomin	CASP3 BAX	1.43e-04	4	112	2	ctd:C072026
Drug	EUK-172	CASP3 BAX	1.43e-04	4	112	2	ctd:C580814
Drug	anthracenylmethyl homospermidine	CASP3 BAX	1.43e-04	4	112	2	ctd:C529696
Drug	ferrous oxide	CASP3 BAX	1.43e-04	4	112	2	ctd:C034236
Drug	gastrodin	CASP3 CPT1A FASN	1.44e-04	21	112	3	ctd:C045345
Drug	Cholesterol, Dietary	CASP3 BAX CPT1A FASN SLC10A1	1.50e-04	102	112	5	ctd:D002791
Drug	AICA ribonucleotide	CASP3 CPT1A CPT1B FASN SLC10A1	1.50e-04	102	112	5	ctd:C031143
Drug	verapamil	CACNA1E ABCC3 ABCA4 SLC26A4 BIRC6 ABCA10 ADCY3 ABCA9 ABCA6 ABCA5	1.55e-04	490	112	10	CID000002520
Drug	AICAR monophosphate	CASP3 CPT1A CPT1B ADCY3 FASN P2RX7	1.57e-04	163	112	6	CID000000200
Drug	Metformin	ABCC3 CASP3 ARFGEF2 BAX RUNX1 CPT1A CCNG1 SLC6A9 FASN	1.63e-04	400	112	9	ctd:D008687
Drug	Dinoprost trometamol [38362-01-5]; Up 200; 8.4uM; HL60; HT_HG-U133A	SLC2A8 ARFGEF2 ZMIZ2 DNAH17 PRKAR1A MCTP2	1.74e-04	166	112	6	2446_UP
Drug	fipronil	ABCC3 MASP1 SLC29A3 CASP3 DLK1 CLIP1 SLC6A9 FASN SLC10A1 DEPDC5 HSD17B11	1.76e-04	597	112	11	ctd:C082360
Drug	nickel acetate	ABCC3 CASP3 BAX RUNX1 FASN	1.88e-04	107	112	5	ctd:C119536
Drug	Glycochenodeoxycholic Acid	CASP3 HUWE1 SLC10A1	1.91e-04	23	112	3	ctd:D005999
Drug	butylbenzyl phthalate	ABCC3 CASP3 BAX FASN HSD17B11	1.96e-04	108	112	5	ctd:C027561
Drug	Doxycycline	ABCC3 CASP3 BAX SLC10A1	2.19e-04	60	112	4	ctd:D004318
Drug	Metaproterenol sulfate, orciprenaline sulfate [5874-97-5]; Up 200; 7.6uM; HL60; HT_HG-U133A	CTSF ZMIZ2 DNAH17 PDE4DIP MCTP2 PADI1	2.31e-04	175	112	6	2485_UP
Drug	TDGA-carnitine	CPT1A CPT1B	2.38e-04	5	112	2	CID000196388
Drug	4 t ha	CPT1A CPT1B	2.38e-04	5	112	2	CID000124503
Drug	ar-turmerone	CASP3 BAX	2.38e-04	5	112	2	ctd:C078098
Drug	1-trichloromethyl-1,2,3,4-tetrahydro-beta-carboline	CASP3 BAX	2.38e-04	5	112	2	ctd:C067372
Drug	bromotetrandrine	CASP3 BAX	2.38e-04	5	112	2	ctd:C514835
Disease	Colorectal Neoplasms	ABCC3 ABCA4 ABCA10 ABCA9 PGM1 PROM1 ABCA6 ABCA5	1.04e-05	277	111	8	C0009404
Disease	intestinal disease (biomarker_via_orthology)	CASP3 BAX	4.20e-05	3	111	2	DOID:5295 (biomarker_via_orthology)
Disease	Stargardt disease	ABCA4 PROM1	4.20e-05	3	111	2	cv:C0271093
Disease	brain glioma (implicated_via_orthology)	CASP3 BAX	1.39e-04	5	111	2	DOID:0060108 (implicated_via_orthology)
Disease	STARGARDT DISEASE 1 (disorder)	ABCA4 PROM1	1.39e-04	5	111	2	C1855465
Disease	Malignant neoplasm of breast	MAGEA4 ABCA4 DYNC2H1 C1orf87 LAMA2 ARFGEF2 BAX CPT1A CLIP1 SLC39A12 FASN EHMT1 UTP20	2.03e-04	1074	111	13	C0006142
Disease	Stargardt's disease	ABCA4 PROM1	2.08e-04	6	111	2	C0271093
Disease	alcohol drinking	SLC26A4 PGM1 LRFN5 TRPM8	2.52e-04	81	111	4	EFO_0004329
Disease	triglycerides:total lipids ratio, low density lipoprotein cholesterol measurement	CPT1A ABCA6 RRN3 IRGC HTT	2.64e-04	150	111	5	EFO_0004611, EFO_0020947
Disease	stromal cell-derived factor 1 measurement	ABCA6 ABCA5	2.91e-04	7	111	2	EFO_0020756
Disease	Mental Depression	SLC29A3 MCHR1 SLCO1C1 P2RX7 IL6R HTT	4.09e-04	254	111	6	C0011570
Disease	lung non-small cell carcinoma (is_marker_for)	CASP3 BAX NUF2 RUNX1 ADAM28	4.56e-04	169	111	5	DOID:3908 (is_marker_for)
Disease	systemic juvenile idiopathic arthritis, polyarticular juvenile idiopathic arthritis, rheumatoid factor negative, oligoarticular juvenile idiopathic arthritis	RUNX1 FASN IL6R	4.63e-04	40	111	3	EFO_1001999, EFO_1002019, EFO_1002020
Disease	pre-malignant neoplasm (implicated_via_orthology)	CASP3 BAX	4.96e-04	9	111	2	DOID:0060071 (implicated_via_orthology)
Disease	middle cerebral artery infarction (implicated_via_orthology)	CASP3 RUNX1 GHSR	6.55e-04	45	111	3	DOID:3525 (implicated_via_orthology)
Disease	congestive heart failure (biomarker_via_orthology)	CASP3 BAX P2RX4 IL6R	7.27e-04	107	111	4	DOID:6000 (biomarker_via_orthology)
Disease	Streptozotocin Diabetes	CASP3 BAX CPT1A CPT1B	7.52e-04	108	111	4	C0038433
Disease	Diabetes Mellitus, Experimental	CASP3 BAX CPT1A CPT1B	7.52e-04	108	111	4	C0011853
Disease	hepatocellular carcinoma (biomarker_via_orthology)	ABCC3 CASP3 BAX CCNG1	7.52e-04	108	111	4	DOID:684 (biomarker_via_orthology)
Disease	Alloxan Diabetes	CASP3 BAX CPT1A CPT1B	7.52e-04	108	111	4	C0002152
Disease	Depressive disorder	SLC29A3 MCHR1 SLCO1C1 P2RX7 IL6R HTT	8.03e-04	289	111	6	C0011581
Disease	bronchopulmonary dysplasia (biomarker_via_orthology)	CASP3 BAX	9.03e-04	12	111	2	DOID:11650 (biomarker_via_orthology)
Disease	low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio	CPT1A ABCA6 RRN3 IRGC HTT	9.75e-04	200	111	5	EFO_0004611, EFO_0020945
Disease	Polydactyly	MKKS DYNC2H1 PROM1 CPLANE1	1.01e-03	117	111	4	C0152427
Disease	Abnormality of refraction	ABCA4 LAMA2 PCDHA5 DLK1 RUNX1 BIRC6 SPPL2A LRFN5 PHACTR3	1.01e-03	673	111	9	HP_0000539
Disease	Charcot-Marie-Tooth disease type 4	SH3TC2 PRX	1.06e-03	13	111	2	cv:C4082197
Disease	microsatellite instability measurement, colorectal cancer, overall survival	DPP10 CCNG1	1.06e-03	13	111	2	EFO_0000638, EFO_0007054, MONDO_0005575
Disease	Colorectal Carcinoma	ABCC3 ABCA4 ABCA10 ABCA9 PGM1 PROM1 P2RX7 ABCA6 ABCA5	1.36e-03	702	111	9	C0009402
Disease	triglycerides:total lipids ratio, intermediate density lipoprotein measurement	CPT1A ABCA6 RRN3 IRGC	1.37e-03	127	111	4	EFO_0008595, EFO_0020947
Disease	Diabetic Angiopathies	CASP3 ADCY3	1.63e-03	16	111	2	C0011875
Disease	Microangiopathy, Diabetic	CASP3 ADCY3	1.63e-03	16	111	2	C0025945
Disease	phosphatidylcholine 38:6 measurement	ABCC3 DEPDC5	1.63e-03	16	111	2	EFO_0010388
Disease	heart disease (biomarker_via_orthology)	CASP3 BAX	1.84e-03	17	111	2	DOID:114 (biomarker_via_orthology)
Disease	glycochenodeoxycholate measurement	CEMIP SLC10A1	1.84e-03	17	111	2	EFO_0010490
Disease	alcoholic hepatitis (biomarker_via_orthology)	CPT1A SLC10A1	2.06e-03	18	111	2	DOID:12351 (biomarker_via_orthology)
Disease	Age-related macular degeneration	ABCA4 HMCN1	2.06e-03	18	111	2	cv:C0242383
Disease	stomach cancer (is_marker_for)	CASP3 BAX NUF2 RUNX1	2.07e-03	142	111	4	DOID:10534 (is_marker_for)
Disease	cognitive function measurement, self reported educational attainment	CACNA1E ARFGEF2 BIRC6 ZMIZ2 ZC3H7B NUP160	2.28e-03	355	111	6	EFO_0004784, EFO_0008354
Disease	migraine disorder	C1orf87 RUNX1 ADAM28 LRFN5 EHMT1 TRPM8	2.35e-03	357	111	6	MONDO_0005277
Disease	corneal hysteresis	ABCA10 ABCA6	2.55e-03	20	111	2	EFO_0010066
Disease	kidney disease (biomarker_via_orthology)	ABCC3 CASP3	2.81e-03	21	111	2	DOID:557 (biomarker_via_orthology)
Disease	nicotine dependence symptom count, depressive symptom measurement	SH3TC2 ARFGEF2 DLK1	2.87e-03	75	111	3	EFO_0007006, EFO_0009262
Disease	serum metabolite measurement	CACNA1E SH3TC2 RUNX1 CPT1A FMO6P SLC39A12 RRN3 DNAH17 TRPM8 SARDH	3.03e-03	945	111	10	EFO_0005653
Disease	dilated cardiomyopathy (biomarker_via_orthology)	CASP3 BAX	3.08e-03	22	111	2	DOID:12930 (biomarker_via_orthology)
Disease	impotence (biomarker_via_orthology)	CASP3 BAX	3.08e-03	22	111	2	DOID:1875 (biomarker_via_orthology)
Disease	Disproportionate short stature	DYNC2H1 SLC26A2 PRKAR1A	3.10e-03	77	111	3	C0878659
Disease	platelet crit	SCFD2 CASS4 ATP13A1 BAX DGKD DLK1 NIBAN2 RUNX1 FBXO47 NUP160	3.19e-03	952	111	10	EFO_0007985
Disease	Epilepsy, Benign Psychomotor, Childhood	P2RX4 P2RX7	3.37e-03	23	111	2	C0393672
Disease	Epilepsy, Lateral Temporal	P2RX4 P2RX7	3.37e-03	23	111	2	C0393682
Disease	Uncinate Epilepsy	P2RX4 P2RX7	3.37e-03	23	111	2	C0014558
Disease	Epilepsy, Temporal Lobe	P2RX4 P2RX7	3.37e-03	23	111	2	C0014556
Disease	Huntington's disease (is_implicated_in)	IL6R HTT	3.37e-03	23	111	2	DOID:12858 (is_implicated_in)
Disease	traumatic brain injury (biomarker_via_orthology)	CASP3 CCNG1	3.67e-03	24	111	2	DOID:0081292 (biomarker_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
CRTKKSSVQEILFPL	ABCA5	26	Q8WWZ7
ELFKHLCISGTPKIR	BIRC6	2061	Q9NR09
RIICEKTLSFPKQAI	CASS4	141	Q9NQ75
RLPKLKAVFDCVVTS	CACNA1E	1271	Q15878
PVKTLSEGIKRKLCF	ABCA10	1336	Q8WWZ4
RKLCFVLSILGNPSV	ABCA10	1346	Q8WWZ4
KRKLSTAIALIGCPP	ABCA4	2076	P78363
KGRIVTFLTCKTFDP	ADAM28	576	Q9UKQ2
APVKTLSEGIKRKLC	ABCA9	1416	Q8IUA7
KRKLCFVLSILGNPS	ABCA9	1426	Q8IUA7
GCFLFISRSKPLKTL	ATP13A1	1026	Q9HD20
QKLTAGITRKLCFVL	ABCA6	1411	Q8N139
LVFRSLCKLSMKPLG	ARFGEF2	376	Q9Y6D5
KGIIKKCRTSPDAFV	CPT1A	556	P50416
ACFITQLLPVKRKLG	GLA	381	P06280
PGIRRLKITSTIKCF	CLSTN1	616	O94985
KPEFTGLTCVKKRAL	DLK1	236	P80370
VCSLESFVKLFIPKR	HSD17B11	16	Q8NBQ5
DFVGIICTRLSPKKI	BCKDK	216	O14874
DRCRSLTGKPKLFII	CASP3	146	P42574
FLCGKPVRPKLTVTI	CEMIP	401	Q8WUJ3
KLFKCGSVVAPITDL	DPP10	666	Q8N608
LPTVKILCQRFSKRG	C1orf87	231	Q8N0U7
TPAVSCIIRKIKAIG	PGM1	96	P36871
KGFRLLLASPSACLK	PADI1	486	Q9ULC6
AKTDPFCPIFRLGKI	P2RX4	221	Q99571
VCAIVPFRSKILLAK	ABCC3	146	O15438
SKIRAFILPKAEVCV	NIBAN2	321	Q96TA1
PNLATLCAKKGLLFV	LRFN5	31	Q96NI6
CRIIFSKAKPSVLAL	CCNG1	191	P51959
FLLLPACVTATKRIT	DEPDC5	946	O75140
RVAPPGKKCAFVLTR	RENBP	106	P51606
LPIKKSTALKVALFC	MKKS	231	Q9NPJ1
RLGTCKVDISALPLK	MCTP2	431	Q6DN12
RCFPVIFGKASESLK	MAGEA4	146	P43358
KTLLKVVGFCRGPAV	CFAP65	451	Q6ZU64
CLAVLKGLYLLRSKP	FICD	51	Q9BVA6
CPKAKRTSRFLSGII	NUF2	111	Q9BZD4
LSETLPGSVKKRVCF	FAM153A	61	Q9UHL3
KMGITTFPKCILRLS	LRRC18	36	Q8N456
SIPFRGCIRSLKLTK	LAMA2	3081	P24043
RILCGTLSIKPSVKE	FMO6P	291	O60774
LLCKITFKSRPSLAP	GGN	241	Q86UU5
TFPLSGHCKVVVKLL	PCDHA5	326	Q9Y5H7
LFGLLVKLCVGSPVR	HUWE1	1066	Q7Z6Z7
APLSTCRKLGLLLKY	IRGC	436	Q6NXR0
QLRLSCKATGIPLPK	HMCN1	4276	Q96RW7
VLIPCTIGIVLKSKR	SLC10A1	166	Q14973
CLKFSPELTVRVKAL	KAT6A	241	Q92794
KKPGACITTSELFRK	P2RX7	501	Q99572
ALFACKTLGLKEVSP	DYNC2H1	3691	Q8NCM8
CSPVLSRKQKGKVLL	HTT	431	P42858
FGTLLCIAIVLRFKK	IL6R	376	P08887
FVLKPRCLQKGSLTI	LIG4	131	P49917
GKRIVLITPSGCIFL	CPLANE1	126	Q9H799
TCLDKLRFGFKKITP	DNAH17	2301	Q9UFH2
CFPLRAKVVVTKGRV	GHSR	146	Q92847
KSVCVLSKLPLYGLL	AVL9	116	Q8NBF6
FASKLVLKALCTKVP	BAX	116	Q07812
SLSLKKPIILRSSGC	REXO1L1P	276	Q8IX06
RLPVSKKTLLCSFQV	CTSF	96	Q9UBX1
ICSLAAIFPRAFPKK	ADCY3	676	O60266
SKCAQPVFLLLVIKS	B3GNT3	101	Q9Y2A9
TCLPVCGLPKFSRKL	MASP1	431	P48740
TKFRKPSVATLVICL	MCHR1	221	Q99705
KRILCGIKELSRSAP	DGKD	1196	Q16760
SLGLLFKRCTLLLPT	FBXO47	116	Q5MNV8
AATVVARGPLKCVKL	PRKAR1A	336	P10644
AATVVARGPLKCVKL	PRKAR1B	336	P31321
IPGKLLFSLVKRYLC	CUL9	251	Q8IWT3
LSTLVKGTRRPVTCK	DUS2	141	Q9NX74
LLQAVLKRGLKPSCT	FASN	766	P49327
AELGKVFPLKRLKCS	FDXACB1	251	Q9BRP7
KKFIAVPARLQTRCG	C4orf54	581	D6RIA3
SRSLIKTLLEKTGCP	SLC39A12	61	Q504Y0
TFKPIFECVITGKLI	CFAP47	2376	Q6ZTR5
CLPFVLAAAVSRKKK	EHMT1	276	Q9H9B1
CEPLKGIFTRPSKLT	CLIP1	111	P30622
KGLIKKCRTSPDAFV	CPT1B	556	Q92523
TCKKGPVIELVFSVL	OR11G2	226	Q8NGC1
LIFRLSLCSKILPGF	OR1P1	176	Q8NH06
SPKLIVGLFCDKKTI	OR4A5	76	Q8NH83
LKSKSTRKPLACIIG	MTA3	521	Q9BTC8
SGTLPRKCKKELLAV	PHACTR3	391	Q96KR7
CNKTLPIAFKVVALG	RUNX1	81	Q01196
LARAKFIPLITVKSC	RRN3	411	Q9NYV6
SKALPGFVLLRTCLI	SLC29A3	376	Q9BZD2
PLKRTCIFKFLGAVA	UTP20	2641	O75691
LRIPSTKRVCLVGKS	TRMT44	491	Q8IYL2
LLTLKRPISGKTFLC	OVCH2	211	Q7RTZ1
RKLSLLLCSVPFVAG	SLC2A8	96	Q9NY64
GPFLRKCFAISLLVI	PROM1	151	O43490
CFLLGRLSIRKVKLS	SH3TC2	531	Q8TF17
PKAVFVLSCLLKGRT	SCFD2	71	Q8WU76
TKSSRLAKPVLCLGT	PLPPR1	221	Q8TBJ4
KLPLTPVFEGLAFKC	NUP160	1236	Q12769
LEAGLAFTCKLKSPV	SARDH	791	Q9UL12
LLFAKGAESSILPKC	ATP11B	591	Q9Y2G3
RNLVFLGISPKCVIK	ZNF616	41	Q08AN1
ICVSSFDGVFKLPKR	RNF225	66	M0QZC1
CSRKRAFGVLKTLVP	SLC26A4	56	O43511
CVILRTQKPKSSLLG	SLC26A2	541	P50443
KVSFCLKRTVPTGDL	PRX	91	Q9BXM0
LLRCIKPQLKSFALG	SLCO1C1	576	Q9NYB5
GIAFCLNLIKTLKLP	SPPL2A	321	Q8TCT8
TLKLPNFKSCVILLG	SPPL2A	331	Q8TCT8
FVLATLLDPCFKGKI	ZBED10P	71	Q96FA7
LARAKFISLITVKPC	RRN3P1	36	Q2M238
VFLCLIRGVKSSGKV	SLC6A9	301	P48067
QTAIKVSLKCPITFR	ZMIZ2	591	Q8NF64
CISVKEGIAIFLLRP	TRPV3	496	Q8NET8
IIPLVGCGFVSFRKK	TRPM8	701	Q7Z2W7
FRKQTPTKALCVLAS	TTC39C	436	Q8N584
VKRLSGICAQIIPFL	TLE2	81	Q04725
VLRAFKVLRTLGSKC	TTI1	926	O43156
SRFCKDVLPKLAGSL	TTI1	946	O43156
ICFDSKPRIISKGTK	ZC3H7B	556	Q9UGR2
VKKIVSLVRSACSFP	PDE4DIP	2201	Q5VU43