Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	maintenance of animal organ identity	NPHP3 IQCB1 USH2A	3.10e-06	5	141	3	GO:0048496
GeneOntologyBiologicalProcess	regulation of organelle assembly	DCDC2 PRICKLE1 CEP120 NF2 EHMT2 SYNE2 WRAP73 HSF1 USP6NL DYNC1H1	2.34e-05	280	141	10	GO:1902115
GeneOntologyBiologicalProcess	organelle assembly	RPGRIP1 DCDC2 MOSPD2 PRICKLE1 TUBGCP4 DTNBP1 NPHP3 CEP120 NDC80 NF2 CCDC42 EHMT2 PAFAH1B1 SYNE2 IQCB1 WRAP73 HSF1 HPS5 DNAH5 USP6NL DYNC1H1	3.10e-05	1138	141	21	GO:0070925
GeneOntologyBiologicalProcess	cilium assembly	RPGRIP1 DCDC2 PRICKLE1 DTNBP1 NPHP3 CEP120 CCDC42 SYNE2 IQCB1 WRAP73 DNAH5 USP6NL	5.56e-05	444	141	12	GO:0060271
GeneOntologyBiologicalProcess	cell projection assembly	RPGRIP1 DCDC2 NCKAP1 PRICKLE1 DOCK11 DTNBP1 NPHP3 CEP120 CCDC42 SYNE2 IQCB1 WRAP73 DNAH5 USP6NL NCKAP1L	7.21e-05	685	141	15	GO:0030031
GeneOntologyBiologicalProcess	nuclear migration	CEP120 PAFAH1B1 SYNE2 DYNC1H1	8.27e-05	34	141	4	GO:0007097
GeneOntologyBiologicalProcess	cilium organization	RPGRIP1 DCDC2 PRICKLE1 DTNBP1 NPHP3 CEP120 CCDC42 SYNE2 IQCB1 WRAP73 DNAH5 USP6NL	1.07e-04	476	141	12	GO:0044782
GeneOntologyCellularComponent	RNA-directed RNA polymerase complex	ZNFX1 TERT	1.37e-04	3	142	2	GO:0031379
GeneOntologyCellularComponent	centrosome	FAM184A DCDC2 TUBGCP4 BIRC6 CEP120 NDC80 CCDC42 MTUS1 PAFAH1B1 IQCB1 WRAP73 HSF1 CABCOCO1 DYNC1H1 DYNC1LI2	2.43e-04	770	142	15	GO:0005813
GeneOntologyCellularComponent	KICSTOR complex	ITFG2 SZT2	2.72e-04	4	142	2	GO:0140007
HumanPheno	Aplasia/Hypoplasia of the cerebellum	RPGRIP1 WWOX OXR1 NDUFA6 TUBGCP4 TERT ALX4 NPHP3 CEP120 SACS PGAP2 PAFAH1B1 IQCB1 MACF1 DENND5A HERC1 USH2A DYNC1H1 ATP6V0A2	1.84e-06	581	52	19	HP:0007360
HumanPheno	Cerebellar hypoplasia	RPGRIP1 WWOX OXR1 NDUFA6 TERT ALX4 NPHP3 CEP120 SACS PGAP2 PAFAH1B1 IQCB1 MACF1 DENND5A HERC1 DYNC1H1 ATP6V0A2	1.03e-05	530	52	17	HP:0001321
HumanPheno	Aplasia/Hypoplasia of the cerebellar vermis	RPGRIP1 WWOX ALX4 NPHP3 CEP120 SACS PGAP2 PAFAH1B1 IQCB1 MACF1 DENND5A DYNC1H1 ATP6V0A2	5.78e-05	369	52	13	HP:0006817
HumanPheno	Cerebellar vermis hypoplasia	RPGRIP1 WWOX ALX4 NPHP3 CEP120 SACS PGAP2 PAFAH1B1 IQCB1 MACF1 DENND5A DYNC1H1 ATP6V0A2	5.78e-05	369	52	13	HP:0001320
HumanPheno	Abnormal cerebellar vermis morphology	RPGRIP1 WWOX ALX4 NPHP3 CEP120 SACS PGAP2 PAFAH1B1 IQCB1 MACF1 DENND5A DYNC1H1 ATP6V0A2	6.64e-05	374	52	13	HP:0002334
Domain	Spectrin	SPTAN1 ACTN3 DST SYNE2 MACF1 MCF2L	1.45e-08	23	140	6	PF00435
Domain	Spectrin_repeat	SPTAN1 ACTN3 DST SYNE2 MACF1 MCF2L	6.57e-08	29	140	6	IPR002017
Domain	SPEC	SPTAN1 ACTN3 DST SYNE2 MACF1 MCF2L	1.23e-07	32	140	6	SM00150
Domain	Spectrin/alpha-actinin	SPTAN1 ACTN3 DST SYNE2 MACF1 MCF2L	1.23e-07	32	140	6	IPR018159
Domain	ACTININ_2	ACTN3 DST SYNE2 MACF1	2.40e-05	23	140	4	PS00020
Domain	ACTININ_1	ACTN3 DST SYNE2 MACF1	2.40e-05	23	140	4	PS00019
Domain	Actinin_actin-bd_CS	ACTN3 DST SYNE2 MACF1	2.40e-05	23	140	4	IPR001589
Domain	Nck-associated_protein-1	NCKAP1 NCKAP1L	5.58e-05	2	140	2	IPR019137
Domain	Nckap1	NCKAP1 NCKAP1L	5.58e-05	2	140	2	PF09735
Domain	CH	ACTN3 DST SYNE2 MACF1 VAV1	1.27e-04	65	140	5	SM00033
Domain	CH	ACTN3 DST SYNE2 MACF1 VAV1	1.80e-04	70	140	5	PF00307
Domain	-	ACTN3 DST SYNE2 MACF1 VAV1	1.93e-04	71	140	5	1.10.418.10
Domain	CH	ACTN3 DST SYNE2 MACF1 VAV1	2.20e-04	73	140	5	PS50021
Domain	CH-domain	ACTN3 DST SYNE2 MACF1 VAV1	2.50e-04	75	140	5	IPR001715
Domain	G-protein_beta_WD-40_rep	FBXW10B FBXW10 STRAP PAFAH1B1 TBL1X	4.47e-04	85	140	5	IPR020472
Domain	-	DST MACF1	8.20e-04	6	140	2	3.90.1290.10
Domain	GAR	DST MACF1	8.20e-04	6	140	2	PS51460
Domain	TLDc_dom	OXR1 IFI44	8.20e-04	6	140	2	IPR006571
Domain	EFhand_Ca_insen	SPTAN1 ACTN3	8.20e-04	6	140	2	PF08726
Domain	GAS2	DST MACF1	8.20e-04	6	140	2	PF02187
Domain	EF-hand_Ca_insen	SPTAN1 ACTN3	8.20e-04	6	140	2	IPR014837
Domain	-	DST MACF1	8.20e-04	6	140	2	3.30.920.20
Domain	GAS_dom	DST MACF1	8.20e-04	6	140	2	IPR003108
Domain	TLD	OXR1 IFI44	8.20e-04	6	140	2	PF07534
Domain	GAS2	DST MACF1	8.20e-04	6	140	2	SM00243
Domain	-	FBXW10B FBXW10 BIRC6 STRAP PAFAH1B1 WRAP73 HERC1 HPS5 TBL1X	9.27e-04	333	140	9	2.130.10.10
Domain	WD40/YVTN_repeat-like_dom	FBXW10B FBXW10 BIRC6 STRAP PAFAH1B1 WRAP73 HERC1 HPS5 TBL1X	9.67e-04	335	140	9	IPR015943
Domain	-	DCDC2 DCDC1	1.14e-03	7	140	2	3.10.20.230
Domain	Plectin	DST MACF1	1.14e-03	7	140	2	PF00681
Domain	Plectin_repeat	DST MACF1	1.14e-03	7	140	2	IPR001101
Domain	PLEC	DST MACF1	1.14e-03	7	140	2	SM00250
Domain	LisH	PAFAH1B1 TBL1X NPAT	1.18e-03	28	140	3	IPR006594
Domain	LisH	PAFAH1B1 TBL1X NPAT	1.18e-03	28	140	3	SM00667
Domain	LISH	PAFAH1B1 TBL1X NPAT	1.18e-03	28	140	3	PS50896
Domain	WD40_repeat_CS	FBXW10B FBXW10 STRAP PAFAH1B1 HERC1 TBL1X	1.49e-03	164	140	6	IPR019775
Domain	DHC_N1	DNAH5 DYNC1H1	1.52e-03	8	140	2	PF08385
Domain	DC	DCDC2 DCDC1	1.52e-03	8	140	2	PS50309
Domain	Dynein_heavy_dom-1	DNAH5 DYNC1H1	1.52e-03	8	140	2	IPR013594
Domain	Doublecortin_dom	DCDC2 DCDC1	1.52e-03	8	140	2	IPR003533
Domain	WD40_repeat_dom	FBXW10B FBXW10 ITFG2 STRAP PAFAH1B1 HERC1 HPS5 TBL1X	1.82e-03	297	140	8	IPR017986
Domain	LisH	PAFAH1B1 TBL1X	1.94e-03	9	140	2	PF08513
Domain	GDS_CDC24_CS	MCF2L VAV1 SOS2	3.09e-03	39	140	3	IPR001331
Domain	WD40	FBXW10B FBXW10 STRAP PAFAH1B1 WRAP73 HERC1 TBL1X	3.42e-03	259	140	7	PF00400
Domain	WD40	FBXW10B FBXW10 STRAP PAFAH1B1 WRAP73 HERC1 TBL1X	4.13e-03	268	140	7	SM00320
Domain	WD40_repeat	FBXW10B FBXW10 STRAP PAFAH1B1 WRAP73 HERC1 TBL1X	4.47e-03	272	140	7	IPR001680
Domain	Dynein_heavy_chain_D4_dom	DNAH5 DYNC1H1	4.79e-03	14	140	2	IPR024317
Domain	VitD_rcpt	NR2C2 ESR2	4.79e-03	14	140	2	IPR000324
Domain	Dynein_HC_stalk	DNAH5 DYNC1H1	4.79e-03	14	140	2	IPR024743
Domain	Dynein_heavy_dom-2	DNAH5 DYNC1H1	4.79e-03	14	140	2	IPR013602
Domain	DHC_N2	DNAH5 DYNC1H1	4.79e-03	14	140	2	PF08393
Domain	ATPase_dyneun-rel_AAA	DNAH5 DYNC1H1	4.79e-03	14	140	2	IPR011704
Domain	MT	DNAH5 DYNC1H1	4.79e-03	14	140	2	PF12777
Domain	AAA_8	DNAH5 DYNC1H1	4.79e-03	14	140	2	PF12780
Domain	AAA_5	DNAH5 DYNC1H1	4.79e-03	14	140	2	PF07728
Domain	WD_REPEATS_1	FBXW10B FBXW10 STRAP PAFAH1B1 WRAP73 HERC1 TBL1X	5.03e-03	278	140	7	PS00678
Domain	WD_REPEATS_2	FBXW10B FBXW10 STRAP PAFAH1B1 WRAP73 HERC1 TBL1X	5.13e-03	279	140	7	PS50082
Domain	WD_REPEATS_REGION	FBXW10B FBXW10 STRAP PAFAH1B1 WRAP73 HERC1 TBL1X	5.13e-03	279	140	7	PS50294
Domain	DHC_fam	DNAH5 DYNC1H1	5.49e-03	15	140	2	IPR026983
Domain	Dynein_heavy	DNAH5 DYNC1H1	5.49e-03	15	140	2	PF03028
Domain	OAR	ALX4 ALX1	5.49e-03	15	140	2	PF03826
Domain	Dynein_heavy_dom	DNAH5 DYNC1H1	5.49e-03	15	140	2	IPR004273
Domain	OAR	ALX4 ALX1	6.25e-03	16	140	2	PS50803
Domain	OAR_dom	ALX4 ALX1	6.25e-03	16	140	2	IPR003654
Domain	SH3_domain	SPTAN1 DST MIA2 MACF1 MCF2L VAV1	6.34e-03	220	140	6	IPR001452
Pathway	REACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3	MOSPD2 NCKAP1 SWAP70 DOCK11 SPTAN1 ARHGAP5 DST NDC80 NF2 PAFAH1B1 MCF2L ARHGAP11B VAV1 DYNC1H1 DYNC1LI2 SOS2 NCKAP1L	1.74e-05	649	114	17	MM15690
Pathway	REACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3	MOSPD2 NCKAP1 SWAP70 DOCK11 SPTAN1 ARHGAP5 DST NDC80 NF2 PAFAH1B1 MCF2L ARHGAP11B VAV1 DYNC1H1 DYNC1LI2 SOS2 NCKAP1L	6.44e-05	720	114	17	M41838
Pathway	REACTOME_RAC1_GTPASE_CYCLE	NCKAP1 SWAP70 DOCK11 ARHGAP5 MCF2L VAV1 SOS2 NCKAP1L	8.64e-05	175	114	8	MM15599
Pathway	REACTOME_RAC1_GTPASE_CYCLE	NCKAP1 SWAP70 DOCK11 ARHGAP5 MCF2L VAV1 SOS2 NCKAP1L	1.23e-04	184	114	8	M41809
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	DCDC2 ADGRA2 BIRC6 ESYT2 DST SYNE2 SIK2 MACF1 HPS5 DOP1B	3.79e-08	225	144	10	12168954
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	GAD2 GALNT2 OXR1 HLA-DRA SPTAN1 HECTD4 NCBP1 ZNFX1 ARHGAP5 MAN1A2 DST MIA2 TTC7B NF2 SACS EHMT2 MACF1 CD74 DYNC1H1 DOP1B SOS2	8.35e-08	1285	144	21	35914814
Pubmed	METTL3 protects METTL14 from STUB1-mediated degradation to maintain m6 A homeostasis.	NCKAP1 CHDH SPTAN1 NCBP1 PSMD13 STRAP HERC1 USH2A PTCD3	5.63e-07	231	144	9	36597993
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	HIPK4 NCKAP1 DOCK11 SPTAN1 ESYT2 MTMR4 DST MTUS1 SYNE2 IQCB1 SIK2 GAN MACF1 PLEKHM3 USP6NL DOP1B	6.25e-07	861	144	16	36931259
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	PMS1 UBR2 MOSPD2 SPTAN1 NCBP1 PSMD13 DTNBP1 BIRC6 ARHGAP5 ESYT2 MTMR4 TTC7B SSH1 NF2 MTUS1 SYNE2 HERC1	1.77e-06	1049	144	17	27880917
Pubmed	Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.	TRPM6 FBXW10B FBXW10 PCGF3 ADAM12 PRMT6 GCNT7 MTMR4 SSH1 EHMT2 PAFAH1B1 DNAH5 ATP6V0A2 TBL1X	2.28e-06	730	144	14	34857952
Pubmed	Identification of phagocytosis regulators using magnetic genome-wide CRISPR screens.	DOCK11 STRAP TBK1 PAFAH1B1 MACF1 DYNC1H1 NCKAP1L	2.35e-06	143	144	7	30397336
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	NCKAP1 DOCK11 SPTAN1 HECTD4 ZNFX1 DST SSH1 STRAP EHMT2 KCNJ1 SPHKAP TBK1 SYNE2 MACF1 DYNC1H1 TBL1X	2.66e-06	963	144	16	28671696
Pubmed	Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods.	TUBGCP4 CEP120 PAFAH1B1 IQCB1 WRAP73 DYNC1H1 DYNC1LI2	2.70e-06	146	144	7	21399614
Pubmed	Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia.	SPTAN1 DTNBP1 DST PAFAH1B1 MACF1 EIF3H DYNC1H1	3.38e-06	151	144	7	17043677
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	EFCAB5 TEX15 TERT LEPR DST MACF1 HERC1 DNAH5	6.39e-06	234	144	8	36243803
Pubmed	Defining the membrane proteome of NK cells.	MOSPD2 GALNT2 LONP2 PSMD13 TUBGCP4 BIRC6 ESYT2 MAN1A2 MIA2 NDC80 NF2 CD74 EIF3H HEATR5B DYNC1H1 DYNC1LI2 NCKAP1L	7.36e-06	1168	144	17	19946888
Pubmed	HENA, heterogeneous network-based data set for Alzheimer's disease.	SPTAN1 DST PAFAH1B1 MACF1 EIF3H DYNC1H1	1.12e-05	120	144	6	31413325
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	PMS1 NR2C2 FAM184A MOSPD2 SPTAN1 PSMD13 NDUFA6 ESYT2 NF2 SACS EHMT2 SYNE2 WRAP73 SIK2 MACF1 USP6NL ATP6V0A2 PTCD3 NPAT	1.31e-05	1487	144	19	33957083
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	KBTBD3 UBR2 WWOX GALNT2 MRPL42 HECTD4 BTAF1 PFKFB1 PCGF3 ALX4 ESYT2 NF2 TBK1 MACF1 DENND5A MCF2L HPS5 TBL1X SOS2	1.33e-05	1489	144	19	28611215
Pubmed	Acf7 (MACF) is an actin and microtubule linker protein whose expression predominates in neural, muscle, and lung development.	DST MACF1	1.70e-05	2	144	2	11002341
Pubmed	Microtubule-binding-induced allostery triggers LIS1 dissociation from dynein prior to cargo transport.	PAFAH1B1 DYNC1H1	1.70e-05	2	144	2	37322240
Pubmed	Circulating anti-BP180 NC16a and anti-BP230 autoantibodies in patients with genital lichen sclerosus do not correlate with disease activity and pruritus.	COL17A1 DST	1.70e-05	2	144	2	24676719
Pubmed	Antidiabetic actions of an estrogen receptor β selective agonist.	ESR2 LEPR	1.70e-05	2	144	2	23349481
Pubmed	Antagonism between the dynein and Ndc80 complexes at kinetochores controls the stability of kinetochore-microtubule attachments during mitosis.	NDC80 DYNC1H1	1.70e-05	2	144	2	29475948
Pubmed	Novel functional features of the Lis-H domain: role in protein dimerization, half-life and cellular localization.	PAFAH1B1 TBL1X	1.70e-05	2	144	2	16258276
Pubmed	The HEM proteins: a novel family of tissue-specific transmembrane proteins expressed from invertebrates through mammals with an essential function in oogenesis.	NCKAP1 NCKAP1L	1.70e-05	2	144	2	7643388
Pubmed	Genetic variants of estrogen beta and leptin receptors may cause gynecomastia in adolescent.	ESR2 LEPR	1.70e-05	2	144	2	24625355
Pubmed	Serum levels of IgE anti-BP180 and anti-BP230 autoantibodies in patients with bullous pemphigoid.	COL17A1 DST	1.70e-05	2	144	2	17920818
Pubmed	Structures of human dynein in complex with the lissencephaly 1 protein, LIS1.	PAFAH1B1 DYNC1H1	1.70e-05	2	144	2	36692009
Pubmed	LIS1 promotes the formation of activated cytoplasmic dynein-1 complexes.	PAFAH1B1 DYNC1H1	1.70e-05	2	144	2	32341549
Pubmed	FBXW10 promotes hepatocarcinogenesis in male patients and mice.	FBXW10B FBXW10	1.70e-05	2	144	2	31400758
Pubmed	Elevated FBXW10 drives hepatocellular carcinoma tumorigenesis via AR-VRK2 phosphorylation-dependent GAPDH ubiquitination in male transgenic mice.	FBXW10B FBXW10	1.70e-05	2	144	2	37450367
Pubmed	Cloning of partial cDNA for mouse 180-kDa bullous pemphigoid antigen (BPAG2), a highly conserved collagenous protein of the cutaneous basement membrane zone.	COL17A1 DST	1.70e-05	2	144	2	1512460
Pubmed	What's new in the pathogeneses and triggering factors of bullous pemphigoid.	COL17A1 DST	1.70e-05	2	144	2	36412277
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	PMS1 GALNT2 LONP2 ZNFX1 BTAF1 TUBGCP4 DST TBK1 SIK2 DENND5A HPS5 ANAPC5	1.81e-05	650	144	12	38777146
Pubmed	Control of a neuronal morphology program by an RNA-binding zinc finger protein, Unkempt.	NCBP1 BIRC6 ARHGAP5 DST EIF3H HERC1 DYNC1H1 NPAT	1.85e-05	271	144	8	25737280
Pubmed	N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.	SWAP70 SPTAN1 BTAF1 DST EHMT2 MACF1 DYNC1H1 DYNC1LI2 PTCD3	2.06e-05	360	144	9	33111431
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	OXR1 NCKAP1 SWAP70 SPTAN1 NCBP1 AASDHPPT PSMD13 BIRC6 AARSD1 PRMT6 STRAP PAFAH1B1 MACF1 EIF3H HERC1 HSF1 DYNC1H1 DYNC1LI2	3.43e-05	1455	144	18	22863883
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	RPGRIP1 NCKAP1 LONP2 PSMD13 TUBGCP4 DTNBP1 PCGF3 FBXO30 NPHP3 CEP120 TBK1 PAFAH1B1 IQCB1 GAN HSF1 DYNC1H1 DYNC1LI2	3.53e-05	1321	144	17	27173435
Pubmed	Multiple mouse chromosomal loci for dynein-based motility.	RBP3 DNAH5 DYNC1H1 DYNC1LI2	4.38e-05	47	144	4	8812413
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	ACTN3 DTNBP1 BIRC6 NPHP3 DST NF2 EHMT2 TBK1 SYNE2 MACF1	4.52e-05	497	144	10	23414517
Pubmed	HLA-DR molecules from an antigen-processing mutant cell line are associated with invariant chain peptides.	HLA-DRA CD74	5.09e-05	3	144	2	1448172
Pubmed	Expression of the mouse Macf2 gene during inner ear development.	DST MACF1	5.09e-05	3	144	2	12399109
Pubmed	LINC complex-Lis1 interplay controls MT1-MMP matrix digest-on-demand response for confined tumor cell migration.	PAFAH1B1 SYNE2	5.09e-05	3	144	2	29934494
Pubmed	Histone methyltransferase G9a modulates hepatic insulin signaling via regulating HMGA1.	LEPR EHMT2	5.09e-05	3	144	2	29101051
Pubmed	Mapping functional regions in the lumenal domain of the class II-associated invariant chain.	HLA-DRA CD74	5.09e-05	3	144	2	7519244
Pubmed	Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1.	HLA-DRA CD74	5.09e-05	3	144	2	8316295
Pubmed	Interaction of HLA-DR and CD74 at the cell surface of antigen-presenting cells by single particle image analysis.	HLA-DRA CD74	5.09e-05	3	144	2	22889831
Pubmed	Dynamic range of Nef-mediated evasion of HLA class II-restricted immune responses in early HIV-1 infection.	HLA-DRA CD74	5.09e-05	3	144	2	25998395
Pubmed	Membrane insertion and oligomeric assembly of HLA-DR histocompatibility antigens.	HLA-DRA CD74	5.09e-05	3	144	2	6955026
Pubmed	Dynein, Lis1 and CLIP-170 counteract Eg5-dependent centrosome separation during bipolar spindle assembly.	PAFAH1B1 DYNC1H1	5.09e-05	3	144	2	19020519
Pubmed	Bullous pemphigoid antigen: cDNA cloning, cellular expression, and evidence for polymorphism of the human gene.	COL17A1 DST	5.09e-05	3	144	2	2045679
Pubmed	Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.	NCKAP1 SWAP70 MRPL42 SPTAN1 AASDHPPT PSMD13 STRAP NDC80 MACF1 EIF3H DYNC1H1 DYNC1LI2 PTCD3	5.44e-05	847	144	13	35235311
Pubmed	A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.	WWOX ARHGAP5 ESYT2 DST TTC7B NF2 MACF1 USP6NL STX6	6.91e-05	421	144	9	36976175
Pubmed	Analysis of interaction partners for eukaryotic translation elongation factor 1A M-domain by functional proteomics.	DST MACF1 HEATR5B	7.53e-05	20	144	3	21689717
Pubmed	Nephronophthisis-Related Ciliopathies	DCDC2 NPHP3 IQCB1	8.75e-05	21	144	3	27336129
Pubmed	Human T cell lymphotropic virus 1 manipulates interferon regulatory signals by controlling the TAK1-IRF3 and IRF4 pathways.	NR2C2 TBK1	1.02e-04	4	144	2	19955181
Pubmed	Association between HLA-DM and HLA-DR in vivo.	HLA-DRA CD74	1.02e-04	4	144	2	8574855
Pubmed	Hypomorphism of Fto and Rpgrip1l causes obesity in mice.	RPGRIP1 LEPR	1.02e-04	4	144	2	27064284
Pubmed	Role of binding of plectin to the integrin beta4 subunit in the assembly of hemidesmosomes.	COL17A1 DST	1.02e-04	4	144	2	14668477
Pubmed	Alx-4, a transcriptional activator whose expression is restricted to sites of epithelial-mesenchymal interactions.	ALX4 ALX1	1.02e-04	4	144	2	9786416
Pubmed	G9a orchestrates PCL3 and KDM7A to promote histone H3K27 methylation.	EHMT2 KDM7A	1.02e-04	4	144	2	26688070
Pubmed	NUDEL is a novel Cdk5 substrate that associates with LIS1 and cytoplasmic dynein.	PAFAH1B1 DYNC1H1	1.02e-04	4	144	2	11163260
Pubmed	Multiple modes of cytoplasmic dynein regulation.	PAFAH1B1 DYNC1H1	1.02e-04	4	144	2	22373868
Pubmed	Regulation of intracellular trafficking of human CD1d by association with MHC class II molecules.	HLA-DRA CD74	1.02e-04	4	144	2	11927549
Pubmed	NudC associates with Lis1 and the dynein motor at the leading pole of neurons.	PAFAH1B1 DYNC1H1	1.02e-04	4	144	2	11734602
Pubmed	Cloning, chromosomal localization, and functional analysis of the murine estrogen receptor beta.	ESR2 SOS2	1.02e-04	4	144	2	9058381
Pubmed	Cloning and characterization of mouse ACF7, a novel member of the dystonin subfamily of actin binding proteins.	DST MACF1	1.02e-04	4	144	2	8954775
Pubmed	A transcription cofactor required for the heat-shock response.	STRAP HSF1	1.02e-04	4	144	2	18451878
Pubmed	Binding of microtubule-associated protein 1B to LIS1 affects the interaction between dynein and LIS1.	PAFAH1B1 DYNC1H1	1.02e-04	4	144	2	15762842
Pubmed	Tumor HLA-DR expression linked to early intrahepatic recurrence of hepatocellular carcinoma.	HLA-DRA CD74	1.02e-04	4	144	2	15688398
Pubmed	Distinct dynein complexes defined by DYNLRB1 and DYNLRB2 regulate mitotic and male meiotic spindle bipolarity.	NDC80 DYNC1H1 DYNC1LI2	1.16e-04	23	144	3	36973253
Pubmed	E-cadherin interactome complexity and robustness resolved by quantitative proteomics.	COL17A1 WWOX SWAP70 SPTAN1 ARHGAP5 ESYT2 DST NF2 MACF1 USP6NL	1.30e-04	565	144	10	25468996
Pubmed	The structure of an intermediate in class II MHC maturation: CLIP bound to HLA-DR3.	HLA-DRA CD74	1.69e-04	5	144	2	7477400
Pubmed	FBXW10-S6K1 promotes ANXA2 polyubiquitination and KRAS activation to drive hepatocellular carcinoma development in males.	FBXW10B FBXW10	1.69e-04	5	144	2	37277019
Pubmed	Physical and genetic interactions between Alx4 and Cart1.	ALX4 ALX1	1.69e-04	5	144	2	9847249
Pubmed	Recruitment of katanin p60 by phosphorylated NDEL1, an LIS1 interacting protein, is essential for mitotic cell division and neuronal migration.	PAFAH1B1 DYNC1H1	1.69e-04	5	144	2	16203747
Pubmed	Role of dynein, dynactin, and CLIP-170 interactions in LIS1 kinetochore function.	PAFAH1B1 DYNC1H1	1.69e-04	5	144	2	11889140
Pubmed	Exchange Factor TBL1 and Arginine Methyltransferase PRMT6 Cooperate in Protecting G Protein Pathway Suppressor 2 (GPS2) from Proteasomal Degradation.	PRMT6 TBL1X	1.69e-04	5	144	2	26070566
Pubmed	A study of the nature of embryonic lethality in LIS1-/- mice.	PAFAH1B1 DYNC1H1	1.69e-04	5	144	2	12950100
Pubmed	Alx3-deficient mice exhibit folic acid-resistant craniofacial midline and neural tube closure defects.	ALX4 ALX1	1.69e-04	5	144	2	20534379
Pubmed	Structure and function of hemidesmosomes: more than simple adhesion complexes.	COL17A1 DST	1.69e-04	5	144	2	10201522
Pubmed	The human HERC family of ubiquitin ligases: novel members, genomic organization, expression profiling, and evolutionary aspects.	HERC1 HERC6	1.69e-04	5	144	2	15676274
Pubmed	BioID reveals an ATG9A interaction with ATG13-ATG101 in the degradation of p62/SQSTM1-ubiquitin clusters.	WWOX OXR1 DST DENND5A HEATR5B USP6NL STX6	1.95e-04	285	144	7	34369648
Pubmed	DYRK1a mediates BAFF-induced noncanonical NF-κB activation to promote autoimmunity and B-cell leukemogenesis.	WWOX SWAP70 ESYT2 TBK1	2.09e-04	70	144	4	34255829
Pubmed	Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.	COL17A1 SWAP70 ZNFX1 DST MACF1	2.14e-04	130	144	5	12421765
Pubmed	Identification of NAP1, a regulatory subunit of IkappaB kinase-related kinases that potentiates NF-kappaB signaling.	NCKAP1 TBK1	2.53e-04	6	144	2	14560022
Pubmed	Mice lacking the MHC class II-associated invariant chain.	HLA-DRA CD74	2.53e-04	6	144	2	7679955
Pubmed	Opposing effects of Ndel1 and alpha1 or alpha2 on cytoplasmic dynein through competitive binding to Lis1.	PAFAH1B1 DYNC1H1	2.53e-04	6	144	2	19622634
Pubmed	Vav1 transduces T cell receptor signals to the activation of the Ras/ERK pathway via LAT, Sos, and RasGRP1.	VAV1 SOS2	2.53e-04	6	144	2	14764585
Pubmed	LIS1 and NDEL1 coordinate the plus-end-directed transport of cytoplasmic dynein.	PAFAH1B1 DYNC1H1	2.53e-04	6	144	2	18784752
Pubmed	The Sos1 and Sos2 Ras-specific exchange factors: differences in placental expression and signaling properties.	NF2 SOS2	2.53e-04	6	144	2	10675333
Pubmed	In vitro reconstitution of a highly processive recombinant human dynein complex.	DYNC1H1 DYNC1LI2	2.53e-04	6	144	2	24986880
Pubmed	Soy-isoflavone-enriched foods and markers of lipid and glucose metabolism in postmenopausal women: interactions with genotype and equol production.	ESR2 LEPR	2.53e-04	6	144	2	16522905
Pubmed	A NUDEL-dependent mechanism of neurofilament assembly regulates the integrity of CNS neurons.	PAFAH1B1 DYNC1H1	2.53e-04	6	144	2	15208636
Pubmed	Assembly of major histocompatibility complex class II subunits with invariant chain.	HLA-DRA CD74	2.53e-04	6	144	2	16242130
Pubmed	Ciliopathy-associated protein CEP290 modifies the severity of retinal degeneration due to loss of RPGR.	RPGRIP1 IQCB1	2.53e-04	6	144	2	26936822
Pubmed	Expression patterns of group-I aristaless-related genes during craniofacial and limb development.	ALX4 ALX1	2.53e-04	6	144	2	11520673
Pubmed	Modelling thymic HIV-1 Nef effects.	HLA-DRA CD74 VAV1	2.60e-04	30	144	3	16454711
Pubmed	C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.	MOSPD2 WWOX ESYT2 DST SYNE2 PLEKHM3 HEATR5B STX6 DOP1B	2.65e-04	504	144	9	34432599
Pubmed	Systematic analysis of human protein complexes identifies chromosome segregation proteins.	TUBGCP4 FBXO30 CEP120 STRAP NDC80 EHMT2 PAFAH1B1 WRAP73 EIF3H HSF1 ANAPC5 DYNC1H1 DYNC1LI2 PTCD3	3.29e-04	1155	144	14	20360068
Pubmed	Trim58 degrades Dynein and regulates terminal erythropoiesis.	DYNC1H1 DYNC1LI2	3.53e-04	7	144	2	25241935
Pubmed	TFAP2 paralogs regulate midfacial development in part through a conserved ALX genetic pathway.	ALX4 ALX1	3.53e-04	7	144	2	38063857
Pubmed	A LIS1/NUDEL/cytoplasmic dynein heavy chain complex in the developing and adult nervous system.	PAFAH1B1 DYNC1H1	3.53e-04	7	144	2	11163259
GeneFamily	7TM orphan receptors	GPR108 GPR157	4.66e-04	6	102	2	310
GeneFamily	WD repeat domain containing	FBXW10B FBXW10 STRAP PAFAH1B1 WRAP73 HERC1 TBL1X	7.10e-04	262	102	7	362
GeneFamily	EF-hand domain containing\|Plakins	DST MACF1	8.63e-04	8	102	2	939
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	SWAP70 DOCK11 PLEKHM3 MCF2L VAV1 SOS2	1.11e-03	206	102	6	682
GeneFamily	Doublecortin superfamily	DCDC2 DCDC1	1.38e-03	10	102	2	1369
GeneFamily	WD repeat domain containing\|F-box and WD repeat domain containing	FBXW10B FBXW10	1.68e-03	11	102	2	559
GeneFamily	Dyneins, cytoplasmic	DYNC1H1 DYNC1LI2	2.36e-03	13	102	2	538
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	PMS1 UBR2 NCKAP1 SWAP70 BTAF1 DST MIA2 NDC80 SACS PAFAH1B1 SYNE2 MACF1 DENND5A TBL1X DOP1B NPAT SOS2	5.00e-06	856	144	17	M4500
CoexpressionAtlas	DevelopingGonad_e14.5_ ovary_emap-6699_top-relative-expression-ranked_1000	NR2C2 MOSPD2 WWOX DOCK11 CPA1 PFKFB1 TEX15 TUBGCP4 BIRC6 FBXO30 ARHGAP5 PLA2R1 SACS PAFAH1B1 SYNE2 IQCB1 GAN HERC1 NPAT	7.62e-07	776	139	19	gudmap_developingGonad_e14.5_ ovary_1000
CoexpressionAtlas	DevelopingGonad_e12.5_ovary_emap-28876_top-relative-expression-ranked_500	NR2C2 MOSPD2 DOCK11 CPA1 TUBGCP4 BIRC6 FBXO30 ALX1 SPHKAP PAFAH1B1 SYNE2 GAN	1.64e-05	409	139	12	gudmap_developingGonad_e12.5_ovary_500
ToppCell	5'-Airway_Nasal-Immune_Myeloid-Dendritic-dendritic_cell-Migratory_DCs\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SWAP70 HLA-DRA SLC25A34 ADAM12 CD74 ATP6V0A2 NCKAP1L	2.40e-06	186	143	7	a558fd00053e7dd6216b01dc8e650c30cee451f1
ToppCell	5'-Airway_Nasal-Immune_Myeloid-Dendritic-dendritic_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SWAP70 HLA-DRA SLC25A34 ADAM12 CD74 ATP6V0A2 NCKAP1L	2.40e-06	186	143	7	75b1f342be5d6dbe0e7acd924a0ca75964f6bab0
ToppCell	5'-Airway_Nasal-Immune_Myeloid-Dendritic-dendritic_cell-Migratory_DCs-\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SWAP70 HLA-DRA SLC25A34 ADAM12 CD74 ATP6V0A2 NCKAP1L	2.40e-06	186	143	7	0c3d195077de7b4c354c127a26116438aef29244
ToppCell	PCW_10-12-Hematologic_Myeloid-Hem_Myeloid_macrophage-im_immature_macrophage1_(2)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	GPR34 HLA-DRA CCRL2 GRIN2C CD74 VAV1 NCKAP1L	2.86e-06	191	143	7	c383ae386bc53e73a683a9543c7dfed2a65257c5
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DCDC2 DCDC1 OXR1 DOCK11 SYNE2 DNAH5 TBL1X	2.86e-06	191	143	7	d0e9afe7b6334dd515d3e68892efdc76347a55e5
ToppCell	CTRL-Myeloid-Alveolar_Macrophage\|CTRL / Disease state, Lineage and Cell class	DOCK11 HLA-DRA DST TTC7B SIK2 CD74 NCKAP1L	3.17e-06	194	143	7	be69b20afa915978c4cf2feb0bb21ab7c1f301a5
ToppCell	LPS_IL1RA-Endothelial-Endothelial\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	NCKAP1 SPTAN1 DST SYNE2 MACF1 MCF2L DYNC1H1	3.87e-06	200	143	7	72ea9882a8ed26fa1534aeb6ba0d1897dccc20c5
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	SPTAN1 BIRC6 LEPR DST SYNE2 MACF1 MCF2L	3.87e-06	200	143	7	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	LPS_IL1RA-Endothelial\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	NCKAP1 SPTAN1 DST SYNE2 MACF1 MCF2L DYNC1H1	3.87e-06	200	143	7	5c092b2ecc081b5d04476c56333c338cd89ab984
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	UBR2 IFI44 BTAF1 BIRC6 SYNE2 MACF1 DYNC1H1	3.87e-06	200	143	7	12f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial-Activated_Gen_Cap\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	HLA-DRA SPTAN1 IFI44 LEPR SYNE2 CD74 MCF2L	3.87e-06	200	143	7	3585484c7e24e941708bee471ca607d8ccee74e6
ToppCell	10x5'-Lung-Lymphocytic_T_CD4-Tnaive/CM_CD4\|Lung / Manually curated celltypes from each tissue	FAM184A DCDC2 TERT ADGB MCF2L DNAH5	1.41e-05	162	143	6	91cc14aec8d580cf97a1929bc1acb00fcbcdb57a
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	GALNT2 SWAP70 HLA-DRA ADK CD74 USP6NL	1.46e-05	163	143	6	6bed27d2f67a430a847da5eb47878d14b4949c45
ToppCell	B_cells-Naive_B_cells_\|B_cells / Immune cells in Kidney/Urine in Lupus Nephritis	SWAP70 HLA-DRA HECTD4 ATP10D BMP3 CD74	2.40e-05	178	143	6	71ac2eca5cf13a91f86b80690748b0788392dcfc
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	HLA-DRA ATP10D PRMT6 ADK CD74	2.83e-05	110	143	5	bc1986e5a496a4d25da3445b6f252f81741619f4
ToppCell	CV-Healthy-7\|CV / Virus stimulation, Condition and Cluster	IFI44 TUBGCP4 FBXO30 ESYT2 GAN USP6NL	2.90e-05	184	143	6	0e5cc77aaa73ceb791f8be7456177577fd2e5586
ToppCell	10x5'-Liver-Lymphocytic_B-Naive_B_cells\|Liver / Manually curated celltypes from each tissue	SWAP70 HLA-DRA ADK BMP3 CD74 USP6NL	3.08e-05	186	143	6	23efdcedbe67f5e6c59106e052f570cd0338f1c1
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DCDC2 OXR1 ADK ESYT2 DST DNAH5	3.17e-05	187	143	6	87b3d0478693d4c54ff06b74e5903036b9c1ee6a
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DCDC2 OXR1 ADK ESYT2 DST DNAH5	3.17e-05	187	143	6	42a1267bfc27b4460b8409ada580a87c4385841c
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DCDC2 OXR1 ADK ESYT2 DST DNAH5	3.17e-05	187	143	6	64afdea159f5e67a1e5cea35ce898aae6e80aea5
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	BTAF1 BIRC6 SYNE2 MACF1 HERC1 DYNC1H1	3.27e-05	188	143	6	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	3'_v3-blood-Myeloid_Dendritic-DC1\|blood / Manually curated celltypes from each tissue	HLA-DRA ADGB ARHGAP5 DST GPR157 CD74	3.27e-05	188	143	6	411d4dd5c9dee7ebd8db352640cf009e7b033ba9
ToppCell	5'-GW_trimst-2-SmallIntestine-Epithelial-epithelial_progenitor_cell-Proximal_progenitor\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FBXW10 TMC7 ACTN3 ESRP2 CDH16	3.36e-05	114	143	5	b350140b389f8762c77a37df473081e1127a8972
ToppCell	Control-Myeloid-Macrophage_Alveolar\|Control / Disease state, Lineage and Cell class	DOCK11 DST TTC7B SIK2 CD74 HEATR5B	3.36e-05	189	143	6	937e876122bc4b94372a4104e9c1a9068c232018
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_B-B_cell\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	GALNT2 SWAP70 HLA-DRA ADK CD74 USP6NL	3.36e-05	189	143	6	886dceacf96e2b6750c146a381da0bf96a2bb15b
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_B\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	GALNT2 SWAP70 HLA-DRA ADK CD74 USP6NL	3.36e-05	189	143	6	5f1f4321939877374a8ee13de93f2d1390af8e2e
ToppCell	3'_v3-bone_marrow-Lymphocytic_B-Naive_B_cells\|bone_marrow / Manually curated celltypes from each tissue	SWAP70 PRICKLE1 HLA-DRA BMP3 CD74 USP6NL	3.46e-05	190	143	6	3d45d5011305f13634013d9eeb98f235517dd54e
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	GALNT2 SWAP70 HLA-DRA ADK CD74 USP6NL	3.46e-05	190	143	6	60bb6aaea9691d07295f61c14d1650f5041a0f9c
ToppCell	10x_3'_v3-lymph_node_(10x_3'_v3)-lymphocytic-B_lymphocytic-naive_B_cell\|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	SWAP70 PRICKLE1 HLA-DRA ATP10D ADK CD74	3.46e-05	190	143	6	441770ce7b3c81f36f5b15b8e51794f736462457
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	GPR34 ACTN3 NANOGNB CD74 VAV1 NCKAP1L	3.57e-05	191	143	6	51f5af610983aa73b9f4ece6f27d281ebff89a04
ToppCell	PCW_13-14-Hematologic_Myeloid-Hem_Myeloid_macrophage-im_immature_macrophage2_(0)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	GPR34 HLA-DRA CCRL2 CD74 VAV1 NCKAP1L	3.57e-05	191	143	6	09dfad8e1fcaaf94775134796b99e4e3fbb9bf40
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	GPR34 ACTN3 NANOGNB CD74 VAV1 NCKAP1L	3.57e-05	191	143	6	8fd6bdc9d2b1c8d364221d7bc68d03921b668ab5
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	FAM184A BTAF1 ESYT2 SYNE2 MACF1 HERC1	3.67e-05	192	143	6	47646d7e4990be85072987f92bf18d52f8da752e
ToppCell	PCW_07-8.5-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_proliferating_myeloid_(8)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	GPR34 HLA-DRA GRIN2C CD74 VAV1 NCKAP1L	3.67e-05	192	143	6	7e7383093efaadceadd4d1f900c2d39cd690102e
ToppCell	facs-Aorta-Heart-3m\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UBR2 OXR1 GPR34 IFI44 MACF1 NCKAP1L	3.67e-05	192	143	6	1ccc47792edf9ee23501c8e2165d11271636b66a
ToppCell	Monocytes-Tissue-resident_macrophages\|Monocytes / Immune cells in Kidney/Urine in Lupus Nephritis	GALNT2 GPR34 HLA-DRA DST CD74 MCF2L	3.78e-05	193	143	6	198552810dcac8d0ca63a78badd6702b49ff6edf
ToppCell	PCW_13-14-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_myeloid_progenitor1_(6)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	GPR34 HLA-DRA GRIN2C CD74 VAV1 NCKAP1L	3.89e-05	194	143	6	a062100ea6cd512a108f9036c259e0cd0f458563
ToppCell	390C-Epithelial_cells-Epithelial-I_(AT1)\|390C / Donor, Lineage, Cell class and subclass (all cells)	KBTBD3 UBR2 PCGF3 AARSD1 ARHGAP5 DST	3.89e-05	194	143	6	88db9f9e80c20ff3474f1f6459dcbdc25aec0b6d
ToppCell	390C-Epithelial_cells-Epithelial-I_(AT1)-\|390C / Donor, Lineage, Cell class and subclass (all cells)	KBTBD3 UBR2 PCGF3 AARSD1 ARHGAP5 DST	3.89e-05	194	143	6	a71728202493d4858342ea2756ea281cd0d99a3a
ToppCell	PCW_10-12-Hematologic_Myeloid\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	GPR34 HLA-DRA CCRL2 CD74 VAV1 NCKAP1L	4.01e-05	195	143	6	6352cd749091cfdbf5cce3c354fa57883cc513e8
ToppCell	3'-GW_trimst-1-LargeIntestine-Hematopoietic-Myeloid-LYVE1+_Macrophage\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GPR34 HLA-DRA GRIN2C CD74 VAV1 NCKAP1L	4.01e-05	195	143	6	c14d730dd5c94247bc09711eaa5a53bd5a5957be
ToppCell	PCW_07-8.5-Hematologic_Myeloid-Hem_Myeloid_monocytic\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	GPR34 HLA-DRA GRIN2C CD74 VAV1 NCKAP1L	4.01e-05	195	143	6	518cc3baeb7cf2ad068692cbe85fd75be67f1872
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GRIN2C DST SPHKAP MACF1 HERC1 DYNC1H1	4.01e-05	195	143	6	3e519cffa6144a62b06124642a14c9ff39b76554
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GRIN2C DST SPHKAP MACF1 HERC1 DYNC1H1	4.01e-05	195	143	6	7796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell	PCW_10-12-Hematologic_Myeloid-Hem_Myeloid_monocytic\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	GPR34 HLA-DRA CCRL2 CD74 VAV1 NCKAP1L	4.12e-05	196	143	6	b904f3a6d6a93e149f5a1b34b6adad5c7894754d
ToppCell	IPF-Endothelial-VE_Peribronchial\|Endothelial / Disease state, Lineage and Cell class	TRPM6 SWAP70 ESR2 SYNE2 SIK2 DENND5A	4.36e-05	198	143	6	b8bd1ba268480f54451648e01631b615a3401144
ToppCell	Control-Control-Lymphocyte-T/NK-CD4+_T_activated\|Control / Disease, condition lineage and cell class	ZBED2 IFI44 PLA2R1 SYNE2 MACF1 HERC6	4.36e-05	198	143	6	ee71543559836fd59adc0da877b2ca538cba60cb
ToppCell	mild-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	UBR2 IFI44 BTAF1 SYNE2 MACF1 HERC1	4.48e-05	199	143	6	f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCell	Control_saline\|World / Treatment groups by lineage, cell group, cell type	SPTAN1 LEPR DST BST1 MACF1 EGFLAM	4.48e-05	199	143	6	11c9c1779caceb725ecccf3f23b7d4e6dbd1af64
ToppCell	CTRL-Myeloid\|CTRL / Disease state, Lineage and Cell class	DOCK11 HLA-DRA DST CD74 DENND5A NCKAP1L	4.48e-05	199	143	6	70b89a930709fdb91fde6f96106add8455b11618
ToppCell	mild-CD4+_Tcm\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	SPTAN1 IFI44 ARHGAP5 SYNE2 MACF1 HERC6	4.48e-05	199	143	6	06c8a0e39f7a33736548f04a5e2263334c8541cf
ToppCell	Control_saline-Endothelial-Endothelial-Gen_Cap\|Control_saline / Treatment groups by lineage, cell group, cell type	SPTAN1 IFI44 LEPR DST MACF1 MCF2L	4.61e-05	200	143	6	3b97920e1e6e2f09ddba2a861baa9c00c2970f4c
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-5w-Neuronal-Intermediate\|5w / Sample Type, Dataset, Time_group, and Cell type.	GAD2 NCKAP1 SPTAN1 HECTD4 MTMR4 PAFAH1B1	4.61e-05	200	143	6	c92e4fc0442404481fcac623d691dae6215b852d
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Gen_Cap\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	SPTAN1 LEPR DST SYNE2 MACF1 MCF2L	4.61e-05	200	143	6	a2b9d1cd291d17abddc3ee2e242121412c864b8b
ToppCell	mild-B_naive\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	SWAP70 HLA-DRA ATP10D ADK CD74 USP6NL	4.61e-05	200	143	6	222789b897e2a683bbfd1d00b6fd8705015d90df
ToppCell	NS-control\|NS / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	NCKAP1 ARHGAP5 DST MTUS1 SYNE2 GAN	4.61e-05	200	143	6	ecbe89ff95d046155b984c8c150e0b9e7278f839
ToppCell	pdx-Tumor_cells-T9\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	SPTAN1 ZNFX1 STRAP DYNC1H1 ATP6V0A2	1.02e-04	144	143	5	0b94d978262a826c9254145aa98c6c30240243f9
ToppCell	Substantia_nigra-Hematopoietic-MICROGLIA\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	GPR34 SLC25A34 MTUS1 VAV1 NCKAP1L	1.24e-04	150	143	5	d44c02402e59a45e40b8fffbe71284032b5e7c92
ToppCell	Substantia_nigra-Hematopoietic-MICROGLIA-MI2(C1qb)\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	GPR34 SLC25A34 MTUS1 VAV1 NCKAP1L	1.24e-04	150	143	5	e020dbcf85c0ba7ad667b8bbeb6bbcfc135c9bb7
ToppCell	Substantia_nigra-Hematopoietic-MICROGLIA-MI2(C1qb)-MICROGLIA_Microglia.C1qb.Tmem119_(Microglia.C1qb.Tmem119)-\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	GPR34 SLC25A34 MTUS1 VAV1 NCKAP1L	1.24e-04	150	143	5	edbc1d29d213bf5908592135700e0d80e123c923
ToppCell	Substantia_nigra-Hematopoietic-MICROGLIA-MI2(C1qb)-MICROGLIA_Microglia.C1qb.Tmem119_(Microglia.C1qb.Tmem119)--\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	GPR34 SLC25A34 MTUS1 VAV1 NCKAP1L	1.24e-04	150	143	5	01c526e1e3007e71e416c317549fddd2919b14e9
ToppCell	Substantia_nigra-Hematopoietic-MICROGLIA-MI2(C1qb)-MICROGLIA_Microglia.C1qb.Tmem119_(Microglia.C1qb.Tmem119)\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	GPR34 SLC25A34 MTUS1 VAV1 NCKAP1L	1.24e-04	150	143	5	b7f5bf9af7ed50aad4da1c71d37b8b9709e6ce85
ToppCell	10x5'-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8\|bone_marrow / Manually curated celltypes from each tissue	FAM184A BTAF1 SYNE2 MACF1 HERC1	1.48e-04	156	143	5	1545169694f686d28648a68b552c2ae606599d66
ToppCell	E12.5-Hematopoietic\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	GPR34 CCRL2 CD74 VAV1 NCKAP1L	1.53e-04	157	143	5	344351c7534440532c6cd4a95782ac90b10d45f3
ToppCell	droplet-Bladder-Unstain-18m-Hematologic-macrophage\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR34 LFNG CD74 VAV1 NCKAP1L	1.58e-04	158	143	5	e5e7b2d609973f1dd4fe7dc62bb69422268ea801
ToppCell	E12.5-Hematopoietic-Immune-immune_cell_unspecified\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	GPR34 CCRL2 CD74 VAV1 NCKAP1L	1.67e-04	160	143	5	5a4a5a50dfdf6af9406e4f685712f7fe390a02f3
ToppCell	E12.5-Hematopoietic-Immune\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	GPR34 CCRL2 CD74 VAV1 NCKAP1L	1.67e-04	160	143	5	cd59830a524c14a1f591c5c615b55510e4104e5b
ToppCell	droplet-Fat-Mat-18m-Myeloid-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR34 CCRL2 CD74 VAV1 NCKAP1L	1.72e-04	161	143	5	8c62ae3fcf304db0f71633e328ceba81a70f03c4
ToppCell	BL-critical-LOC-Myeloid-Basophil\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	GPR34 ZSCAN9 LFNG ATP10D ATP6V0A2	1.77e-04	162	143	5	25ec9df914445b4daae4fd28fd0e60b64797c46d
ToppCell	droplet-Bladder-nan-3m-Hematologic-macrophage\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR34 ADGB CD74 VAV1 NCKAP1L	1.77e-04	162	143	5	0cee9ef405765f3f82d0cd7b8adc88f6e9fdbb5c
ToppCell	Posterior_cortex-Hematopoietic-MICROGLIA-MI2(C1qb)-Tmem119\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	FBXW10 GPR34 CD74 VAV1 NCKAP1L	1.98e-04	166	143	5	063d68f2ffb40770cb4601fa1cb6426ae26f7a37
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Macrophage_Dendritic-Classical_Dendritic_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	HLA-DRA ADGB CD74 PLEKHM3 HPS5	1.98e-04	166	143	5	63dc58864268b4e7779e4c45155022556fc634f9
ToppCell	5'-Adult-LymphNode-Hematopoietic-Myeloid-Lymphoid_DC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HLA-DRA ADAM12 GPR157 CD74 NCKAP1L	1.98e-04	166	143	5	da10d0be6b616199d49dd922591c2901f9681583
ToppCell	Posterior_cortex-Hematopoietic-MICROGLIA-MI2(C1qb)-Tmem119-MICROGLIA_Microglia.C1qb.Tmem119-Junb_(Microglia)-\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	FBXW10 GPR34 CD74 VAV1 NCKAP1L	1.98e-04	166	143	5	417cfb207da08fa1a0fd5f2a13c8786628667a8e
ToppCell	Posterior_cortex-Hematopoietic-MICROGLIA-MI2(C1qb)-Tmem119-MICROGLIA_Microglia.C1qb.Tmem119-Junb_(Microglia)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	FBXW10 GPR34 CD74 VAV1 NCKAP1L	1.98e-04	166	143	5	f28d07715e6b00ca2a0df39273c5f569744be5a8
ToppCell	3'-Child04-06-SmallIntestine-Hematopoietic-T_cells-TRGV5/7_gdT\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CCRL2 CEP120 ZNF468 HERC1 ATP6V0A2	2.04e-04	167	143	5	18e336faa2d2429ab49d1c6ae9bbf9923d74aa8d
ToppCell	facs-Lung-EPCAM-24m-Endothelial-Lymphatic_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MOSPD2 TMC7 ESYT2 NPHP3 USP6NL	2.04e-04	167	143	5	961e722442d786ab15d1e490941d2be265a9057a
ToppCell	P15-Epithelial-airway_epithelial_cell-ciliated_cell_of_airway\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PFKFB1 FBXO30 BST1 HEATR5B CDH16	2.04e-04	167	143	5	5c3d0763f73628c71c71f9883556bb4f1639f3cc
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	DOCK11 GPR34 SLC25A34 BTAF1 BIRC6	2.04e-04	167	143	5	063ec29b32e40aaa138a691da3a79ee8eef0c2be
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Immune-Myeloid-Granulocytic-Mast_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ESR2 GRIN2C VAV1 ATP6V0A2 NCKAP1L	2.04e-04	167	143	5	a813b95c2fafb638b249bc4fa4f708c6f39ad444
ToppCell	facs-Lung-EPCAM-24m-Endothelial-endothelial_cell_of_lymphatic_vessel\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MOSPD2 TMC7 ESYT2 NPHP3 USP6NL	2.04e-04	167	143	5	3760efc35d4e7e9c2da1a20f9795ddea397e2206
ToppCell	droplet-Thymus-nan-24m-Lymphocytic-nan\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR34 SLC25A34 ALX4 DST CD74	2.10e-04	168	143	5	04a7810f95196a21325356b42084f96c11af5964
ToppCell	facs-Heart-RV-3m-Myeloid-monocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR34 BST1 CD74 VAV1 NCKAP1L	2.10e-04	168	143	5	8ee57814c7e9d45444f48b6b269c4d535bc4d5e1
ToppCell	facs-Heart-RV-3m-Myeloid\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR34 BST1 CD74 VAV1 NCKAP1L	2.10e-04	168	143	5	c1a5f4f4d32a1f8583048db709a7037cc9357ad8
ToppCell	facs-Heart-RV-3m-Myeloid-monocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR34 BST1 CD74 VAV1 NCKAP1L	2.10e-04	168	143	5	a405f0de70293f68b4e000c1fc8a9ad33d56539a
ToppCell	Mild/Remission-B_naive-4\|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)	HLA-DRA ADK MACF1 CD74 HEATR5B	2.15e-04	169	143	5	c3a6179a64589a370108fea809b157839347759c
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FAM184A ESR2 ADK MTUS1 SYNE2	2.21e-04	170	143	5	a2c738e441ced90eeeb1fcc6ca3269b918aaa298
ToppCell	3'_v3-blood-Lymphocytic_B-Naive_B_cells\|blood / Manually curated celltypes from each tissue	SWAP70 HLA-DRA BMP3 CD74 USP6NL	2.34e-04	172	143	5	f16f90d17feac1ee52fd513907b28456865fd31d
ToppCell	PBMC-Mild-Lymphocyte-B-B_cell-B_naive-B_naive-4\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SWAP70 HLA-DRA ADK CD74 USP6NL	2.34e-04	172	143	5	62ed3b70fa1f6c84ea80ff00f60d2562be292e9d
ToppCell	droplet-Spleen-SPLEEN-30m-Myeloid-macrophage_dendritic_cell_progenitor\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HIPK4 CHDH ADAM12 ARHGAP5 SYNE2	2.34e-04	172	143	5	30916a902c151907745756d14327e24adc34afef
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-B_cell\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	SWAP70 HLA-DRA ADK CD74 USP6NL	2.40e-04	173	143	5	d56e337eae727a29cd53cfd628e1b3c0a98e1f51
ToppCell	normal_Lymph_Node-Myeloid_cells-pDCs\|Myeloid_cells / Location, Cell class and cell subclass	AARSD1 DST SIK2 ZNF468 HEATR5B	2.47e-04	174	143	5	2274648b80dd74f3c948a779bba3391095964c34
ToppCell	Healthy_donor-Treg\|World / disease group, cell group and cell class (v2)	FAM184A CHDH SPTAN1 ADAM12 SYNE2	2.47e-04	174	143	5	dc3b06420b0ad9c7060571e7bf5714e028d598bf
ToppCell	facs-Marrow-T_cells-18m-Myeloid-CD4+_macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPGRIP1 CHDH IFI44 ARHGAP5 PLEKHM3	2.60e-04	176	143	5	74f851a398c7562dd713bc0d8d488c0037243112
ToppCell	normal_Lymph_Node-Myeloid_cells-pDCs\|normal_Lymph_Node / Location, Cell class and cell subclass	DST SIK2 DENND5A ZNF468 HEATR5B	2.60e-04	176	143	5	476794ef75ce5ab732d78cfeb4944e2f841e3e92
ToppCell	facs-Marrow-T_cells-18m-Myeloid-macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPGRIP1 CHDH IFI44 ARHGAP5 PLEKHM3	2.60e-04	176	143	5	31b5459a978d5cdde0af03a77401e0464d8c95ba
ToppCell	NS-moderate-d_0-4-Myeloid-pDC\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DOCK11 ESR2 FBXO30 DENND5A NCKAP1L	2.67e-04	177	143	5	de1ffe3df76100d46ca158bdd2fea2ebbd4656b4
ToppCell	PBMC-Convalescent-Lymphocyte-B-B_cell-B_naive-B_naive-9\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SWAP70 HLA-DRA FBXO30 GPR157 USP6NL	2.67e-04	177	143	5	ae55773c531099a9e94f44f01ba48b5e71dddc53
ToppCell	metastatic_Brain-Myeloid_cells-Activated_DCs\|metastatic_Brain / Location, Cell class and cell subclass	HLA-DRA GPR157 CD74 HPS5 ATP6V0A2	2.67e-04	177	143	5	739496fcc4156f4d5e3de9cd21cf3856037f0678
ToppCell	droplet-Marrow-nan-3m-Lymphocytic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHDH IFI44 ARHGAP5 CD74 PLEKHM3	2.81e-04	179	143	5	dcaf2191134a586d50ebaf67dcf5b815b54a722b
Disease	glycosyl ceramide (d16:1/24:1, d18:1/22:1) measurement	ATP10D SYNE2	6.59e-05	3	139	2	EFO_0800530
Disease	hepatocellular clear cell carcinoma (is_marker_for)	TERT LEPR	6.59e-05	3	139	2	DOID:5016 (is_marker_for)
Disease	growth/differentiation factor 11/8 measurement	PMS1 ACTN3	1.31e-04	4	139	2	EFO_0021962
Disease	Ciliopathies	RPGRIP1 NPHP3 IQCB1 DNAH5 USH2A	1.78e-04	110	139	5	C4277690
Disease	Sterility, Reproductive	LEPR EHMT2	2.18e-04	5	139	2	C4074771
Disease	quality of life during menstruation measurement, Arthralgia	GAD2 DOP1B	2.18e-04	5	139	2	EFO_0009366, HP_0002829
Disease	Frontonasal dysplasia	ALX4 ALX1	2.18e-04	5	139	2	C1876203
Disease	Subfertility	LEPR EHMT2	2.18e-04	5	139	2	C0729353
Disease	Infertility	LEPR EHMT2	2.18e-04	5	139	2	C0021359
Disease	FEV/FEC ratio	EFCAB5 FAM184A CPA1 ADAM12 ADK DST TTC7B MTUS1 GPR157 SYNE2 KDM7A DENND5A HERC1 DNAH5 ATP6V0A2 PTCD3	2.27e-04	1228	139	16	EFO_0004713
Disease	nephronophthisis (is_implicated_in)	NPHP3 IQCB1	3.26e-04	6	139	2	DOID:12712 (is_implicated_in)
Disease	glucagon measurement, glucose tolerance test	MACF1 HERC1	3.26e-04	6	139	2	EFO_0004307, EFO_0008463
Disease	Lissencephaly	PAFAH1B1 MACF1	3.26e-04	6	139	2	C0266463
Disease	glycosyl ceramide (d18:1/20:0, d16:1/22:0) measurement	ATP10D SYNE2	4.56e-04	7	139	2	EFO_0800551
Disease	melanoma (is_marker_for)	ESR2 TERT EHMT2	5.03e-04	33	139	3	DOID:1909 (is_marker_for)
Disease	pancreatitis (implicated_via_orthology)	CPA1 LEPR	7.76e-04	9	139	2	DOID:4989 (implicated_via_orthology)
Disease	idiopathic pulmonary fibrosis (is_implicated_in)	TERT EHMT2	7.76e-04	9	139	2	DOID:0050156 (is_implicated_in)
Disease	cortical thickness	FBXW10 WWOX DCDC1 ADAM12 ADGRA2 ALX4 LFNG CEP120 ALX1 PAFAH1B1 MACF1 CABCOCO1 STX6 SOS2	8.00e-04	1113	139	14	EFO_0004840
Disease	systemic juvenile idiopathic arthritis	WWOX HLA-DRA EIF3H	8.90e-04	40	139	3	EFO_1001999
Disease	sleep apnea	ACTN3 CEP120 MACF1	8.90e-04	40	139	3	EFO_0003877
Disease	Hermanski-Pudlak Syndrome	DTNBP1 HPS5	9.67e-04	10	139	2	C0079504
Disease	Hermansky-Pudlak syndrome	DTNBP1 HPS5	9.67e-04	10	139	2	cv:C0079504
Disease	waist circumference	ESR2 HECTD4 TEX15 PRMT6 CEP120 EHMT2 SYNE2 DNAH5	1.01e-03	429	139	8	EFO_0004342
Disease	testosterone measurement	TRPM6 FAM184A WWOX DCDC1 ESR2 BIRC6 LEPR PRMT6 CEP120 SYNE2 MACF1 PLEKHM3 USH2A TBL1X SOS2	1.02e-03	1275	139	15	EFO_0004908
Disease	epilepsy (implicated_via_orthology)	GAD2 WWOX PRICKLE1 GRIN2C DYNC1H1	1.07e-03	163	139	5	DOID:1826 (implicated_via_orthology)
Disease	peanut allergy measurement, parental genotype effect measurement	MRPL42 ADGB	1.18e-03	11	139	2	EFO_0005939, EFO_0007017
Disease	gastrointestinal stromal tumor (is_implicated_in)	TERT NF2	1.18e-03	11	139	2	DOID:9253 (is_implicated_in)
Disease	Amelogenesis Imperfecta	COL17A1 KCNJ1	1.41e-03	12	139	2	C0002452
Disease	Renal dysplasia and retinal aplasia (disorder)	NPHP3 IQCB1	1.41e-03	12	139	2	C0403553
Disease	chronic kidney disease (implicated_via_orthology)	TERT LEPR	1.41e-03	12	139	2	DOID:784 (implicated_via_orthology)
Disease	cardiovascular disease	DCDC1 SWAP70 CHDH LFNG ADK MCF2L CABCOCO1 SOS2	1.50e-03	457	139	8	EFO_0000319
Disease	developmental disorder of mental health (implicated_via_orthology)	NCKAP1 GRIN2C NCKAP1L	1.61e-03	49	139	3	DOID:0060037 (implicated_via_orthology)
Disease	Malignant neoplasm of breast	WWOX ESR2 SPTAN1 ADAM12 TERT LEPR MIA2 NF2 KCNJ1 SYNE2 MACF1 CD74 ANAPC5	1.74e-03	1074	139	13	C0006142
Disease	rostral middle frontal gyrus volume measurement	ADGB PLA2R1	1.93e-03	14	139	2	EFO_0010328
Disease	diacylglycerol 42:7 measurement	ESR2 SYNE2	1.93e-03	14	139	2	EFO_0020068
Disease	Hermansky-Pudlak syndrome (implicated_via_orthology)	DTNBP1 HPS5	1.93e-03	14	139	2	DOID:3753 (implicated_via_orthology)
Disease	platelet storage pool deficiency (implicated_via_orthology)	DTNBP1 HPS5	2.22e-03	15	139	2	DOID:2223 (implicated_via_orthology)
Disease	Cocaine-Related Disorders	GAD2 ESR2 PRMT6 EHMT2	2.32e-03	117	139	4	C0236736
Disease	factor XI measurement, fibrinogen measurement, tissue plasminogen activator measurement, factor VII measurement	HECTD4 LEPR MCF2L	2.36e-03	56	139	3	EFO_0004619, EFO_0004623, EFO_0004694, EFO_0004791
Disease	fibrinogen measurement, factor VII measurement	HECTD4 LEPR MCF2L	2.61e-03	58	139	3	EFO_0004619, EFO_0004623
Disease	level of Sphingomyelin (d32:1) in blood serum	ESR2 SYNE2	2.86e-03	17	139	2	OBA_2045173
Disease	sex interaction measurement, ulcerative colitis	HLA-DRA EHMT2	2.86e-03	17	139	2	EFO_0000729, EFO_0008343
Disease	Cocaine Abuse	GAD2 ESR2 PRMT6 EHMT2	3.12e-03	127	139	4	C0009171
Disease	age at menopause	TUBGCP4 ADGRA2 BIRC6 ESYT2 DYNC1H1 STX6	3.15e-03	302	139	6	EFO_0004704
Disease	serum amyloid A-1 protein measurement	LEPR HPS5	3.21e-03	18	139	2	EFO_0008282
Disease	Meckel syndrome type 1	RPGRIP1 NPHP3	3.21e-03	18	139	2	C3714506
Disease	Cannabis use initiation	WWOX GPR157	3.21e-03	18	139	2	EFO_0007586
Disease	mean platelet volume	GALNT2 DOCK11 PSMD13 TERT LEPR LFNG ESYT2 SSH1 PAFAH1B1 SYNE2 MCF2L VAV1	3.28e-03	1020	139	12	EFO_0004584
Disease	Disorder of eye	RPGRIP1 RBP3 NPHP3 IQCB1 USH2A	3.37e-03	212	139	5	C0015397
Disease	neutrophil count, eosinophil count	UBR2 HECTD4 PCGF3 TERT LEPR	3.44e-03	213	139	5	EFO_0004833, EFO_0004842
Disease	Calcium channel blocker use measurement	SWAP70 CHDH LFNG CABCOCO1 SOS2	3.44e-03	213	139	5	EFO_0009930
Disease	transient cerebral ischemia (implicated_via_orthology)	ESR2 TERT HSF1	3.46e-03	64	139	3	DOID:224 (implicated_via_orthology)
Disease	Coronary Arteriosclerosis	ESR2 HECTD4 TERT	3.61e-03	65	139	3	C0010054
Disease	Coronary Artery Disease	ESR2 HECTD4 TERT	3.61e-03	65	139	3	C1956346
Disease	temporal lobe epilepsy (is_marker_for)	DTNBP1 ADK	3.96e-03	20	139	2	DOID:3328 (is_marker_for)
Disease	Benign Neoplasm	TERT BIRC6 HSF1	4.10e-03	68	139	3	C0086692
Disease	Neoplasms	TERT BIRC6 HSF1	4.10e-03	68	139	3	C0027651
Disease	neutrophil count, basophil count	UBR2 HECTD4 PCGF3 TERT LEPR	4.26e-03	224	139	5	EFO_0004833, EFO_0005090
Disease	Cocaine Dependence	GAD2 ESR2 PRMT6 EHMT2	4.30e-03	139	139	4	C0600427
Disease	refractive error	CHDH ESRP2 BMP3 KCNJ1 TBL1X NPAT	4.57e-03	326	139	6	MONDO_0004892

Protein segments in the cluster

Peptide	Gene	Start	Entry
LRMKAKEHTANISWA	ALX1	311	Q15699
LRMKAKEHSAAISWA	ALX4	396	Q9H161
HSDSQEELWMFVRKK	COL17A1	541	Q9UMD9
ISSLKVWTSHMKRTI	PFKFB1	296	P16118
DTERAEWLNKTVKHM	ESYT2	191	A0FGR8
KEKITRIEIWVMHEI	BST1	216	Q10588
HRDIMSWLSKDITQL	BMP3	191	P12645
HIMKRKFTNKEWETI	AASDHPPT	146	Q9NRN7
WKHFLTLKMNISVLV	CCRL2	196	O00421
DKKWTSIHERIQMDS	EGFLAM	186	Q63HQ2
KNSHLINVLMWELEK	EIF3H	206	O15372
NLKTLHMSLEESIKW	CABCOCO1	21	Q8IVU9
HLDLEKNWMLVEKAR	ADK	166	P55263
IWDVSKLMKVHLKFE	BIRC6	411	Q9NR09
VFHLSLWRLMKKVQI	ADGB	841	Q8N7X0
LWMGVKARVLHKELT	ADGRA2	851	Q96PE1
KETWLALLTIMEHTL	CPA1	401	P15085
VKVWHIAMAQLVKTL	FBXW10	556	Q5XX13
WKEIVHKTNEIMLVL	GPR34	301	Q9UPC5
VLKWMERSHGTEKAL	AARSD1	246	Q9BTE6
TSLHEFLDWRKMKLL	ADAM12	281	O43184
WAAEHKHIEVIRMLL	EHMT2	791	Q96KQ7
TSLLRHAKVVWEMLK	ADCK5	526	Q3MIX3
HAKVVWEMLKFEVAL	ADCK5	531	Q3MIX3
SIWLLEKKKETEIMH	CCDC42	41	Q96M95
KTLEELAWKHHMAIE	FAM184A	481	Q8NB25
IEALHKAGIKIWMLT	ATP10D	906	Q9P241
DVLAGSKRLSWKIHM	CHDH	76	Q8NE62
MLTRKIKLWDINAHI	PCGF3	1	Q3KNV8
SGDRIKQVMEHIWKL	NR2C2	461	P49116
VLMVSVLLHHWKALK	ARHGAP11B	236	Q3KRB8
HIVSASRDKTIKMWE	PAFAH1B1	206	P43034
EEEMVLKVVLSWTKH	KBTBD3	211	Q8NAB2
IMSSLWKKLDHTLSQ	NPAT	81	Q14207
WKKLDHTLSQIRSMQ	NPAT	86	Q14207
NKLMDALKDSDLLHW	ANAPC5	396	Q9UJX4
VKVWHIAMAQLVKTL	FBXW10B	556	O95170
HMLLTCILWRLTKKH	PGAP2	156	Q9UHJ9
KDHLLLIKKVTWTMN	DCDC1	251	M0R2J8
LLMSRKHKWKLSGVE	GAD2	371	Q05329
EKWSKILELLRHMVA	PTCD3	311	Q96EY7
HTALKLWMKKELVSE	KDM7A	436	Q6ZMT4
LWMKKELVSEHAFEI	KDM7A	441	Q6ZMT4
DVMKESAHLAISWLR	LONP2	691	Q86WA8
DLLLETWISRHKEMT	LFNG	131	Q8NES3
LADKELVHMISWAKK	ESR2	301	Q92731
FVWEILHSTIRKMNK	NCBP1	636	Q09161
VELIKRMLTWESHER	HIPK4	321	Q8NE63
KRLSMENEELLWKLH	MTUS1	1221	Q9ULD2
EKFWCDHMSLIVTIK	DST	6161	Q03001
WKSIIDHLLTHEKTM	DOP1B	1991	Q9Y3R5
EWALTKEKSVKHMDL	GALNT2	481	Q10471
LIDAHKDTLISMKWD	HERC1	3621	Q15751
LRMVLQEWLSHLEKT	HPS5	636	Q9UPZ3
KWASVLREHIDKMKI	DYNC1LI2	151	O43237
SKLLAMKHENEALWR	HSF1	156	Q00613
MIIDLLTDHKTISVW	OR4L1	81	Q8NH43
VDSEVVMLSAHWEKK	DTNBP1	76	Q96EV8
EETIKVWKQRTHVMR	NDUFA6	91	P56556
MAEKWIAVKRRSTEH	HERC6	386	Q8IVU3
LMWHVTSQIVELKKL	NCKAP1L	856	P55160
LEQKWHVVSSKMEER	MACF1	2546	O94854
LISHQRMKKLFWEDV	LEPR	861	P48357
RIRSTVAEHLWKLMV	TUBGCP4	331	Q9UGJ1
KGSIDEVDKRVHMTW	PSMD13	321	Q9UNM6
MIWDHCKSRLLETKA	PLEKHM3	71	Q6ZWE6
HAQKASRKWTLEMDV	HECTD4	3451	Q9Y4D8
HLTGQLVSLKKWMLE	ITFG2	166	Q969R8
MWHISSQVAELKKLV	NCKAP1	856	Q9Y2A7
SWLERSEKELENMHK	MACF1	3896	Q9UPN3
VALLEQKWHVVSSKM	MACF1	6416	Q9UPN3
TKWLQHLSVMLKAAV	MTMR4	376	Q9NYA4
EELWKSKKHSVMSRQ	INSL5	101	Q9Y5Q6
TVAWLKMDKKVLDHD	NF2	71	P35240
EHWISDNMVKSKTEL	PRICKLE1	441	Q96MT3
EELRKLWKTHTMQQT	OXR1	501	Q8N573
WIHICSALMKITKQL	EFCAB5	1461	A4FU69
DVTLRWKKDGQLLMH	IGSF22	446	Q8N9C0
AVEKLSHWLMLCKDV	HEATR5B	1181	Q9P2D3
MAVTTRLTWLHEKIL	IFI44	1	Q8TCB0
MKLWTIHELLQDSKP	CCDC107	151	Q8WV48
ELRKTWLDSMAKIHV	DOCK11	1616	Q5JSL3
DLIHKVWMELLSKAS	BTAF1	581	O14981
IHAKDMLQWSKDIRS	GCNT7	296	Q6ZNI0
LVELWHKDKMSKDLL	CEP120	531	Q8N960
RWIAHDTEIRKVHMK	GAN	201	Q9H2C0
LEAKDHVLWMLLTGK	GPR157	161	Q5UAW9
MLSSVLHARTKWLKE	PRMT6	166	Q96LA8
AWVRLSMEKKLLSRH	DENND5A	886	Q6IQ26
IFHVDMAKKETVWRL	HLA-DRA	56	P01903
KSLELHRRLETSMKW	MCF2L	456	O15068
LKAWLMSDKTDHEAR	MAN1A2	406	O60476
MEEKSALIIQKHWRG	IQCB1	386	Q15051
LMKRLHVNWVVSELT	DYNC1H1	1416	Q14204
LRHLKNTMETIDWKV	CD74	166	P04233
EWKFADILSMADHLK	FBXO30	691	Q8TB52
LVHEDIPMKTAEWLK	SACS	1421	Q9NZJ4
VIWQKSRVSDHKMAL	PMS1	196	P54277
WDHVLQMVTEKITLR	DCDC2	166	Q9UHG0
LILIFTHWTMSRKKD	CDH16	801	O75309
SNIDKSWVKIMTRAH	DNAH5	1656	Q8TE73
HIKTLTERLLKMKDW	MIA2	871	Q96PC5
ESSKAVHKKMWREFR	FAM74A4	96	Q5TZK3
LSWRHNIVDETLKML	MOSPD2	51	Q8NHP6
EVKLVLLWKHNMRIE	SZT2	426	Q5T011
MTLGRILVKKWIHLS	USH2A	201	O75445
IHETWASSIEALMRK	SPHKAP	1306	Q2M3C7
FRLREDHMLVKELSW	RPGRIP1	51	Q96KN7
KMIRHTTNLTLWFEK	SOS2	821	Q07890
EHWALMEELNRSKKD	RNF8	346	O76064
WTEKALQKMELHQLT	SYNE2	1661	Q8WXH0
HDVIHWIKEIKESLM	SYNE2	2051	Q8WXH0
HTILSMLFWDELRKL	SLC25A34	281	Q6PIV7
KRLTLKLMQHSWSVS	NPHP3	576	Q7Z494
ASLWKMVKEIEISQH	RPL37AP8	21	A6NKH3
KIHWLMAALAFTKSI	GPR108	291	Q9NPR9
KRLVSKSLMHTLWAK	NANOGNB	106	Q7Z5D8
TIAQIKEHKWMLIEV	SIK2	261	Q9H0K1
KLAKVSHMTSDRRQW	STX6	221	O43752
KVRILNHVTWKMITE	WRAP73	246	Q9P2S5
IEHLNWSEALKLMEK	ARHGAP5	356	Q13017
WEVKTMVAVILHLLK	ESRP2	201	Q9H6T0
FHSEKVLMKRTWREA	PLA2R1	681	Q13018
VRLWDHATMTEVKSL	STRAP	166	Q9Y3F4
MVLRLWSDTKIHLDG	SSH1	141	Q8WYL5
KASLHEAWTRGKEEM	ACTN3	416	Q08043
LKIWSMKQEVCIHDL	TBL1X	436	O60907
KLRHASLKVIWKVMS	TAS2R7	291	Q9NYW3
QKHLEIERTTKWLKM	USP6NL	66	Q92738
TALWKHLKSMHREEL	ZBED2	96	Q9BTP6
MAWDRVDIAKKHILI	TRPM6	416	Q9BX84
RLLVEHIWKKIMHTD	RBP3	1061	P10745
VKWVMSKRTILKHLF	MRPL42	6	Q9Y6G3
SKAIEARHASLMKRW	SPTAN1	2051	Q13813
DRDNKKWSHMFLLIE	VAV1	461	P15498
SRILEEWHKAKVEAM	WWOX	166	Q9NZC7
EWHKAKVEAMTLDLA	WWOX	171	Q9NZC7
HLASLWDSLKKMHVL	ZNFX1	1711	Q9P2E3
WDSLKKMHVLEEKRV	ZNFX1	1716	Q9P2E3
EALLTCKHMLQIWKS	TTC7B	601	Q86TV6
MGSLKEELLKAIWHA	SWAP70	1	Q9UH65
ELLTMKVEAKSHLQW	ZSCAN9	21	O15535
KQDHLWIIIEMISSK	TEX15	1851	Q9BXT5
YLEVHKDMIRWILKT	UBR2	981	Q8IWV8
LLTQKWEVHMREKSF	ZNF468	201	Q5VIY5
LREEILAKFLHWLMS	TERT	536	O14746
AFLNKSEEWIRKMLH	TBK1	611	Q9UHD2
SEEWIRKMLHLRKQL	TBK1	616	Q9UHD2
FLEKAREMTTHLELW	TMC7	131	Q7Z402
AEHKKMVLWNDSVVR	ATP6V0A2	496	Q9Y487
LTESMFKHLRKWVVT	KCNJ1	16	P48048
VWLIDCIKIHTAMKE	NDC80	186	O14777
IAMQKDSHWKRAIDL	GRIN2C	761	Q14957