Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	negative regulation of ossification	TRPM4 P2RY2 SMAD6 SMAD7	1.35e-05	50	60	4	GO:0030279
GeneOntologyCellularComponent	heteromeric SMAD protein complex	SMAD6 SMAD7	2.47e-04	8	63	2	GO:0071144
GeneOntologyCellularComponent	SMAD protein complex	SMAD6 SMAD7	3.96e-04	10	63	2	GO:0071141
Domain	SCAN	ZNF394 ZNF197 ZNF202 ZSCAN2	3.79e-05	56	63	4	SM00431
Domain	SCAN_BOX	ZNF394 ZNF197 ZNF202 ZSCAN2	4.35e-05	58	63	4	PS50804
Domain	SCAN	ZNF394 ZNF197 ZNF202 ZSCAN2	4.35e-05	58	63	4	PF02023
Domain	SCAN_dom	ZNF394 ZNF197 ZNF202 ZSCAN2	4.35e-05	58	63	4	IPR003309
Domain	Retrov_capsid_C	ZNF394 ZNF197 ZNF202 ZSCAN2	4.65e-05	59	63	4	IPR008916
Domain	Dwarfin	SMAD6 SMAD7	3.09e-04	8	63	2	IPR013790
Domain	DWB	SMAD6 SMAD7	3.09e-04	8	63	2	SM00524
Domain	MH2	SMAD6 SMAD7	3.09e-04	8	63	2	PS51076
Domain	MH1	SMAD6 SMAD7	3.09e-04	8	63	2	PS51075
Domain	-	SMAD6 SMAD7	3.09e-04	8	63	2	3.90.520.10
Domain	MAD_homology_MH1	SMAD6 SMAD7	3.09e-04	8	63	2	IPR013019
Domain	MH2	SMAD6 SMAD7	3.09e-04	8	63	2	PF03166
Domain	SMAD_dom_Dwarfin-type	SMAD6 SMAD7	3.09e-04	8	63	2	IPR001132
Domain	F-box-like	FBXO24 FBXL17 FBXO17	4.39e-04	44	63	3	PF12937
Domain	FBOX	FBXO24 FBXL17 FBXO17	7.18e-04	52	63	3	SM00256
Domain	MAD_homology1_Dwarfin-type	SMAD6 SMAD7	7.23e-04	12	63	2	IPR003619
Domain	DWA	SMAD6 SMAD7	7.23e-04	12	63	2	SM00523
Domain	MH1	SMAD6 SMAD7	7.23e-04	12	63	2	PF03165
Domain	SMAD_dom-like	SMAD6 SMAD7	1.30e-03	16	63	2	IPR017855
Domain	-	SMAD6 SMAD7	1.30e-03	16	63	2	2.60.200.10
Domain	F-box	FBXO24 FBXL17 FBXO17	1.50e-03	67	63	3	PF00646
Domain	FBOX	FBXO24 FBXL17 FBXO17	1.85e-03	72	63	3	PS50181
Domain	F-box_dom	FBXO24 FBXL17 FBXO17	2.08e-03	75	63	3	IPR001810
Domain	-	B4GALNT4 GALNT12 HAS1	2.59e-03	81	63	3	3.90.550.10
Domain	Nucleotide-diphossugar_trans	B4GALNT4 GALNT12 HAS1	3.27e-03	88	63	3	IPR029044
Domain	Glycos_transf_2	GALNT12 HAS1	4.58e-03	30	63	2	PF00535
Domain	Glyco_trans_2-like	GALNT12 HAS1	4.58e-03	30	63	2	IPR001173
Domain	VWFC_1	JAG2 AMN	6.55e-03	36	63	2	PS01208
Pubmed	Inhibitory Smad proteins promote the differentiation of mouse embryonic stem cells into ependymal-like ciliated cells.	SMAD6 SMAD7	3.44e-06	2	65	2	20807502
Pubmed	Inhibitory SMADs: potential regulators of ovarian function.	SMAD6 SMAD7	3.44e-06	2	65	2	25550343
Pubmed	Expressions of inhibitory Smads, Smad6 and Smad7, are differentially regulated by TPA in human lung fibroblast cells.	SMAD6 SMAD7	3.44e-06	2	65	2	15033458
Pubmed	A genome-wide association study shows that common alleles of SMAD7 influence colorectal cancer risk.	SMAD6 SMAD7	3.44e-06	2	65	2	17934461
Pubmed	Prognostic value of the expression of Smad6 and Smad7, as inhibitory Smads of the TGF-beta superfamily, in esophageal squamous cell carcinoma.	SMAD6 SMAD7	3.44e-06	2	65	2	15736400
Pubmed	Defective bone morphogenic protein signaling underlies hepcidin deficiency in HFE hereditary hemochromatosis.	SMAD6 SMAD7	3.44e-06	2	65	2	20658468
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	TAOK2 JAG2 RNF223 TRPM4 B4GALNT4 KMT2B DNAJC14 NTSR1 STEAP3 ATP13A2 SMAD7	5.90e-06	1105	65	11	35748872
Pubmed	Bone morphogenetic protein and transforming growth factor beta inhibitory Smads 6 and 7 are expressed in human adult normal and osteoarthritic cartilage in vivo and are differentially regulated in vitro by interleukin-1beta.	SMAD6 SMAD7	1.03e-05	3	65	2	15529348
Pubmed	Hsa-miR-186-5p regulates TGFβ signaling pathway through expression suppression of SMAD6 and SMAD7 genes in colorectal cancer.	SMAD6 SMAD7	1.03e-05	3	65	2	33938174
Pubmed	Minor contribution of SMAD7 and KLF10 variants to genetic susceptibility of type 2 diabetes.	SMAD6 SMAD7	1.03e-05	3	65	2	17931948
Pubmed	Inhibitory smads and tgf-Beta signaling in glomerular cells.	SMAD6 SMAD7	1.03e-05	3	65	2	12397035
Pubmed	Yes-associated protein (YAP65) interacts with Smad7 and potentiates its inhibitory activity against TGF-beta/Smad signaling.	SMAD6 SMAD7	1.03e-05	3	65	2	12118366
Pubmed	Genetic susceptibility to keloid scarring: SMAD gene SNP frequencies in Afro-Caribbeans.	SMAD6 SMAD7	1.03e-05	3	65	2	18445023
Pubmed	Smad6 inhibits signalling by the TGF-beta superfamily.	SMAD6 SMAD7	2.06e-05	4	65	2	9335505
Pubmed	Inhibition of BMP2-induced, TAK1 kinase-mediated neurite outgrowth by Smad6 and Smad7.	SMAD6 SMAD7	2.06e-05	4	65	2	11737269
Pubmed	Downregulation of ZEB1 and overexpression of Smad7 contribute to resistance to TGF-beta1-mediated growth suppression in adult T-cell leukemia/lymphoma.	SMAD6 SMAD7	2.06e-05	4	65	2	20514018
Pubmed	Modulation of thrombomodulin-dependent activation of human protein C through differential expression of endothelial Smads.	SMAD6 SMAD7	2.06e-05	4	65	2	12407115
Pubmed	FAM105A/OTULINL Is a Pseudodeubiquitinase of the OTU-Class that Localizes to the ER Membrane.	JAG2 TRPM4 HYOU1 DNAJC14 FBXO17 TMCO1 ZFPL1	2.71e-05	468	65	7	31056421
Pubmed	Developmentally regulated expression of Smad3, Smad4, Smad6, and Smad7 involved in TGF-beta signaling.	SMAD6 SMAD7	3.43e-05	5	65	2	11231077
Pubmed	FKBP12 functions as an adaptor of the Smad7-Smurf1 complex on activin type I receptor.	SMAD6 SMAD7	3.43e-05	5	65	2	16720724
Pubmed	FOXD4a and FOXD4b, two new winged helix transcription factors, are expressed in human leukemia cell lines.	FOXD4L4 FOXD4L5	3.43e-05	5	65	2	12234674
Pubmed	Promoting bone morphogenetic protein signaling through negative regulation of inhibitory Smads.	SMAD6 SMAD7	3.43e-05	5	65	2	11483516
Pubmed	Degradation of the tumor suppressor Smad4 by WW and HECT domain ubiquitin ligases.	SMAD6 SMAD7	3.43e-05	5	65	2	15817471
Pubmed	Smad7 Inhibits chondrocyte differentiation at multiple steps during endochondral bone formation and down-regulates p38 MAPK pathways.	SMAD6 SMAD7	5.13e-05	6	65	2	18644788
Pubmed	Fine-tuning BMP7 signalling in adipogenesis by UBE2O/E2-230K-mediated monoubiquitination of SMAD6.	SMAD6 SMAD7	5.13e-05	6	65	2	23455153
Pubmed	Vascular MADs: two novel MAD-related genes selectively inducible by flow in human vascular endothelium.	SMAD6 SMAD7	5.13e-05	6	65	2	9256479
Pubmed	Neural transcription factors bias cleavage stage blastomeres to give rise to neural ectoderm.	FOXD4L4 FOXD4L5	5.13e-05	6	65	2	27092474
Pubmed	SMAD expression in the testis: an insight into BMP regulation of spermatogenesis.	SMAD6 SMAD7	5.13e-05	6	65	2	18069690
Pubmed	Smad6 and Smad7 are co-regulated with hepcidin in mouse models of iron overload.	SMAD6 SMAD7	5.13e-05	6	65	2	22960056
Pubmed	A family of mammalian F-box proteins.	FBXO24 FBXL17 FBXO17	6.79e-05	42	65	3	10531037
Pubmed	Can't get no SMADisfaction: Smad proteins as positive and negative regulators of TGF-beta family signals.	SMAD6 SMAD7	7.18e-05	7	65	2	10376010
Pubmed	Arkadia amplifies TGF-beta superfamily signalling through degradation of Smad7.	SMAD6 SMAD7	7.18e-05	7	65	2	14657019
Pubmed	Regulation of transforming growth factor-beta signaling by protein inhibitor of activated STAT, PIASy through Smad3.	SMAD6 SMAD7	7.18e-05	7	65	2	12815042
Pubmed	STRAP and Smad7 synergize in the inhibition of transforming growth factor beta signaling.	SMAD6 SMAD7	7.18e-05	7	65	2	10757800
Pubmed	Remarkable versatility of Smad proteins in the nucleus of transforming growth factor-beta activated cells.	SMAD6 SMAD7	9.56e-05	8	65	2	10647776
Pubmed	The novel E3 ubiquitin ligase Tiul1 associates with TGIF to target Smad2 for degradation.	SMAD6 SMAD7	9.56e-05	8	65	2	15359284
Pubmed	Smurf1 interacts with transforming growth factor-beta type I receptor through Smad7 and induces receptor degradation.	SMAD6 SMAD7	9.56e-05	8	65	2	11278251
Pubmed	Smad7 inhibits transforming growth factor-beta family type i receptors through two distinct modes of interaction.	SMAD6 SMAD7	9.56e-05	8	65	2	20663871
Pubmed	TGF-beta signaling by Smad proteins.	SMAD6 SMAD7	9.56e-05	8	65	2	10708949
Pubmed	The mouse fkh-2 gene. Implications for notochord, foregut, and midbrain regionalization.	FOXD4L4 FOXD4L5	9.56e-05	8	65	2	8530406
Pubmed	An amphioxus winged helix/forkhead gene, AmphiFoxD: insights into vertebrate neural crest evolution.	FOXD4L4 FOXD4L5	1.23e-04	9	65	2	12412011
Pubmed	Holding their own: the noncanonical roles of Smad proteins.	SMAD6 SMAD7	1.23e-04	9	65	2	19018011
Pubmed	TGF-beta signal transduction.	SMAD6 SMAD7	1.23e-04	9	65	2	9759503
Pubmed	Axin is a scaffold protein in TGF-beta signaling that promotes degradation of Smad7 by Arkadia.	SMAD6 SMAD7	1.23e-04	9	65	2	16601693
Pubmed	Smad7 Protein Interacts with Receptor-regulated Smads (R-Smads) to Inhibit Transforming Growth Factor-β (TGF-β)/Smad Signaling.	SMAD6 SMAD7	1.23e-04	9	65	2	26555259
Pubmed	The Smad pathway.	SMAD6 SMAD7	1.23e-04	9	65	2	10708948
Pubmed	NEDD4-2 (neural precursor cell expressed, developmentally down-regulated 4-2) negatively regulates TGF-beta (transforming growth factor-beta) signalling by inducing ubiquitin-mediated degradation of Smad2 and TGF-beta type I receptor.	SMAD6 SMAD7	1.23e-04	9	65	2	15496141
Pubmed	Negative regulation of transforming growth factor-beta (TGF-beta) signaling by WW domain-containing protein 1 (WWP1).	SMAD6 SMAD7	1.53e-04	10	65	2	15221015
Pubmed	Smad6 inhibits BMP/Smad1 signaling by specifically competing with the Smad4 tumor suppressor.	SMAD6 SMAD7	1.53e-04	10	65	2	9436979
Pubmed	Tob1 controls dorsal development of zebrafish embryos by antagonizing maternal beta-catenin transcriptional activity.	SMAD6 SMAD7	1.53e-04	10	65	2	16890162
Pubmed	Spatio-temporal distribution of Smads and role of Smads/TGF-β/BMP-4 in the regulation of mouse bladder organogenesis.	SMAD6 SMAD7	1.53e-04	10	65	2	23620745
Pubmed	Human BAMBI cooperates with Smad7 to inhibit transforming growth factor-beta signaling.	SMAD6 SMAD7	1.87e-04	11	65	2	19758997
Pubmed	Systematic analysis and nomenclature of mammalian F-box proteins.	FBXO24 FBXL17 FBXO17	2.08e-04	61	65	3	15520277
Pubmed	Smad expression during kidney development.	SMAD6 SMAD7	2.24e-04	12	65	2	14656760
Pubmed	Cloning and characterization of seven human forkhead proteins: binding site specificity and DNA bending.	FOXD4L4 FOXD4L5	2.65e-04	13	65	2	7957066
Pubmed	TGF-beta signaling is dynamically regulated during the alveolarization of rodent and human lungs.	SMAD6 SMAD7	2.65e-04	13	65	2	18095342
Pubmed	Neuronal Ceroid-Lipofuscinoses – RETIRED CHAPTER, FOR HISTORICAL REFERENCE ONLY	GRN ATP13A2	2.65e-04	13	65	2	20301601
Pubmed	A genetic study of the suppressors of the Engrailed-1 cerebellar phenotype.	FOXD4L4 FOXD4L5	2.65e-04	13	65	2	16884697
Pubmed	Inductive interactions mediated by interplay of asymmetric signalling underlie development of adult haematopoietic stem cells.	SMAD6 SMAD7	3.08e-04	14	65	2	26952187
Pubmed	Endocardial cushion and myocardial defects after cardiac myocyte-specific conditional deletion of the bone morphogenetic protein receptor ALK3.	SMAD6 SMAD7	3.08e-04	14	65	2	11854453
Pubmed	TSC-22 promotes transforming growth factor β-mediated cardiac myofibroblast differentiation by antagonizing Smad7 activity.	SMAD6 SMAD7	3.08e-04	14	65	2	21791611
Pubmed	The essential role of Cited2, a negative regulator for HIF-1alpha, in heart development and neurulation.	SMAD6 SMAD7	3.08e-04	14	65	2	12149478
Pubmed	Systematic protein-protein interaction mapping for clinically relevant human GPCRs.	TRPM4 TRAP1 DNAJC14 ADGRB1 FBXO17 SLC45A4 SMAD6	3.20e-04	697	65	7	28298427
Pubmed	A High-Density Map for Navigating the Human Polycomb Complexome.	MTA1 KMT2B FBXL17 GRN NOL9 FBXO17	3.27e-04	495	65	6	27705803
Pubmed	Six members of the mouse forkhead gene family are developmentally regulated.	FOXD4L4 FOXD4L5	3.56e-04	15	65	2	7689224
Pubmed	Strain-specific modifier genes of Cecr2-associated exencephaly in mice: genetic analysis and identification of differentially expressed candidate genes.	FOXD4L4 FOXD4L5	3.56e-04	15	65	2	22045912
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	TAOK2 JAG2 HYOU1 AARS2 HS6ST2 GALNT12 TMCO1 ZFPL1	3.62e-04	942	65	8	31073040
Pubmed	Expression of the winged helix genes fkh-4 and fkh-5 defines domains in the central nervous system.	FOXD4L4 FOXD4L5	4.06e-04	16	65	2	8861101
Pubmed	Developmental competence of the gut endoderm: genetic potentiation by GATA and HNF3/fork head proteins.	FOXD4L4 FOXD4L5	4.06e-04	16	65	2	10208738
Pubmed	The FBXL5-IRP2 axis is integral to control of iron metabolism in vivo.	SMAD6 SMAD7	4.06e-04	16	65	2	21907140
Pubmed	The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.	TAOK2 AMN LRP10 ZDHHC16 ELAPOR1 STRA6 TMCO1 SPACA3	4.87e-04	985	65	8	12975309
Pubmed	Hereditary Dystonia Overview	KMT2B GRN ATP13A2	4.97e-04	82	65	3	20301334
Pubmed	p63 Suppresses non-epidermal lineage markers in a bone morphogenetic protein-dependent manner via repression of Smad7.	SMAD6 SMAD7	5.16e-04	18	65	2	19717565
Pubmed	Functional equivalency between Otx2 and Otx1 in development of the rostral head.	FOXD4L4 FOXD4L5	5.76e-04	19	65	2	9895322
Pubmed	Forkhead transcription factor Foxf2 (LUN)-deficient mice exhibit abnormal development of secondary palate.	FOXD4L4 FOXD4L5	6.39e-04	20	65	2	12812790
Pubmed	Rnf165/Ark2C enhances BMP-Smad signaling to mediate motor axon extension.	SMAD6 SMAD7	7.06e-04	21	65	2	23610558
Pubmed	Sequential roles for Otx2 in visceral endoderm and neuroectoderm for forebrain and midbrain induction and specification.	FOXD4L4 FOXD4L5	7.06e-04	21	65	2	9449667
Pubmed	Crucial roles of Foxa2 in mouse anterior-posterior axis polarization via regulation of anterior visceral endoderm-specific genes.	FOXD4L4 FOXD4L5	7.76e-04	22	65	2	17389379
Pubmed	USP15 targets ALK3/BMPR1A for deubiquitylation to enhance bone morphogenetic protein signalling.	SMAD6 SMAD7	7.76e-04	22	65	2	24850914
Pubmed	Bone morphogenetic proteins.	SMAD6 SMAD7	8.48e-04	23	65	2	15621726
Pubmed	Global genetic analysis in mice unveils central role for cilia in congenital heart disease.	AMN DNAH5 SMAD6	8.85e-04	100	65	3	25807483
Pubmed	Otx2 is required to respond to signals from anterior neural ridge for forebrain specification.	FOXD4L4 FOXD4L5	9.24e-04	24	65	2	11820816
Pubmed	A Requirement for Zic2 in the Regulation of Nodal Expression Underlies the Establishment of Left-Sided Identity.	FOXD4L4 FOXD4L5	9.24e-04	24	65	2	29992973
Pubmed	Ssdp1 regulates head morphogenesis of mouse embryos by activating the Lim1-Ldb1 complex.	FOXD4L4 FOXD4L5	1.09e-03	26	65	2	15857913
Pubmed	SERBP1 Promotes Stress Granule Clearance by Regulating 26S Proteasome Activity and G3BP1 Ubiquitination and Protects Male Germ Cells from Thermostimuli Damage.	RBM15 TRAP1 MTA1 HYOU1 AARS2 STEAP3 TMCO1	1.25e-03	878	65	7	37223481
Pubmed	Molecular profiling of synovial joints: use of microarray analysis to identify factors that direct the development of the knee and elbow.	FOXD4L4 FOXD4L5	1.35e-03	29	65	2	22972626
Pubmed	SMAD4 target genes are part of a transcriptional network that integrates the response to BMP and SHH signaling during early limb bud patterning.	SMAD6 SMAD7	1.35e-03	29	65	2	34822715
Pubmed	N-cadherin can structurally substitute for E-cadherin during intestinal development but leads to polyp formation.	SMAD6 SMAD7	1.45e-03	30	65	2	20534673
Interaction	SLC39A4 interactions	LRP10 P2RY2 STEAP3 TMCO1 ATP13A2 ZFPL1	9.81e-06	163	61	6	int:SLC39A4
Cytoband	14q32.3	MTA1 AMN	8.82e-05	10	65	2	14q32.3
Cytoband	8q24.3	WDR97 ADGRB1 SLC45A4	5.67e-04	113	65	3	8q24.3
Cytoband	9q21.11	FOXD4L4 FOXD4L5	8.37e-04	30	65	2	9q21.11
Cytoband	19q13.1	PRODH2 KMT2B	2.79e-03	55	65	2	19q13.1
Cytoband	Ensembl 112 genes in cytogenetic band chr9q21	SPATA31D1 FOXD4L4 FOXD4L5	2.88e-03	199	65	3	chr9q21
Cytoband	Ensembl 112 genes in cytogenetic band chr7q22	FBXO24 ZNF394 PILRA	3.76e-03	219	65	3	chr7q22
GeneFamily	SMAD family	SMAD6 SMAD7	1.68e-04	8	45	2	750
ToppCell	Sigmoid-T_cell-Tcm\|T_cell / Region, Cell class and subclass	AMN PILRA ELAPOR1 PLD6 ZSCAN2 FBXO17	4.62e-07	199	65	6	acdf95f4d58df47690f4ae254245bc618f9ac07e
Drug	Bacampicillin hydrochloride [37661-08-8]; Down 200; 8uM; PC3; HT_HG-U133A	JAG2 MTMR11 KMT2B GPATCH3 ZNF197 ZNF202 SMAD7	1.54e-06	198	65	7	4592_DN
Disease	nephritis (biomarker_via_orthology)	SMAD6 SMAD7	2.06e-04	11	58	2	DOID:10952 (biomarker_via_orthology)
Disease	pulmonary hypertension (biomarker_via_orthology)	HAS1 SMAD6 SMAD7	5.32e-04	80	58	3	DOID:6432 (biomarker_via_orthology)
Disease	sexual dimorphism measurement	TAOK2 TLCD3B MTMR11 KMT2B GPATCH3 ZSCAN2 DCST1 ATP13A2	1.38e-03	1106	58	8	EFO_0021796

Protein segments in the cluster

Peptide	Gene	Start	Entry
CRRRLIPHPRRLWPF	CDRT15L2	26	A8MXV6
WRGCRTVPLDALRTR	ADGRB1	906	O14514
KCLRREAPRWDAPLR	GRN	571	P28799
GPVWRWRLRAAPRCR	IBA57	16	Q5T440
PLLRRAGRLRWRRHE	AMN	381	Q9BXJ7
QELWRRLLPGCRRIP	PRODH2	521	Q9UF12
RRSPRWRRAVPLCET	RBM15	11	Q96T37
CLLPWAVRRRRCPLQ	PDZRN4	41	Q6ZMN7
RRRPAWLPVRLRSWA	SLC34A3	536	Q8N130
RRPRRRLGSLRWCGR	NOL9	31	Q5SY16
RCLTLLRDSRPWQRL	DNAJC14	376	Q6Y2X3
LVRRLRRWGLLPRTN	LRP10	556	Q7Z4F1
LATLACLCPVWRRRR	NTSR1	376	P30989
CLCPVWRRRRKRPAF	NTSR1	381	P30989
QIRLWRRCYLRGRPE	MTMR11	631	A4FU01
PRARCWAGTCRPRRR	FOXD4L4	401	Q8WXT5
RGRLPRRLLLLLALW	JAG2	6	Q9Y219
CLLRPWRPLRARGCA	ECHDC2	6	Q86YB7
GRTERRIPRLWRLLL	ELAPOR1	16	Q6UXG2
GTLCLRIFRWGPRRR	INHBE	136	P58166
GTWLPGRCLIRRLRL	GPATCH3	131	Q96I76
LGLRRGLRRLRRLWA	KMT2B	71	Q9UMN6
RCLGVLRPLRSLRWG	P2RY2	131	P41231
RSLVTRCRPVCRAWR	FBXO17	36	Q96EF6
ILGLICLLRWRRRKG	PILRA	211	Q9UKJ1
WPCGRRRRHRARRAL	GALR3	306	O60755
RWKPLWGVRLRLRPC	ATP13A2	66	Q9NQ11
RRQRPRRRVCWALVA	HYOU1	6	Q9Y4L1
LHRGCPLLRRWLCRR	DCST1	631	Q5T197
CSWCRRRRPLLRLPR	FBXL17	21	Q9UF56
RLWRLRPGARRSLSA	COQ7	11	Q99807
MWGRTARRRCPRELR	GALNT12	1	Q8IXK2
LTLYWVGVRRLCRRR	HAS1	556	Q92839
EGVWRRICRRLSPRL	FBXO24	76	O75426
LRRRWDLGSLCRALL	HS6ST2	101	Q96MM7
RRPAKAWSGRRTRLC	GPR15L	26	Q6UWK7
RSRALRRRWCPAGIM	SPACA3	56	Q8IXA5
RRRLELWLRSRPTGT	DNAH5	2501	Q8TE73
NPVPRTLRCWRLRRA	LRRC72	6	A6NJI9
EALPWVLRWLRSRRR	PLD6	21	Q8N2A8
RALSPWRVRVQRRRC	TMCO1	36	Q9UM00
RSGLVRRLWRSRVVP	SMAD6	6	O43541
PRARCWAGTCRPRRR	FOXD4L5	401	Q5VV16
RVRRGISRLWLRVLL	TAOK2	1076	Q9UL54
IARRLCREILRPWHA	MTA1	481	Q13330
RLRRAIRRSPAWRGL	AARS2	11	Q5JTZ9
VRRRQLWPDCVRGRP	STRA6	71	Q9BX79
GRPELCRPLRLAWRQ	B4GALNT4	806	Q76KP1
RCLRPRPLAWRRLVP	PAK6-AS1	21	Q8N910
DPAPRRGRLARCWAR	RNF223	176	E7ERA6
RCTLSWGRRRPFILA	SLC45A4	111	Q5BKX6
LWTRLRTLRAPELRR	RINL	361	Q6ZS11
LLREQWPERRRCHRL	RAPGEF3	506	O95398
RPRGVKRRWRLSRIV	MRPS14	96	O60783
RSALVRRLWRSRAPG	SMAD7	6	O15105
SRLRELCRRWLRPEA	ZNF197	61	O14709
ALSRLRELCRRWLRP	ZNF394	81	Q53GI3
RELCRRWLRPELLSK	ZNF394	86	Q53GI3
ALGRLRELCRRWLRP	ZSCAN2	76	Q7Z7L9
LPCISRRLARIRRGW	STEAP3	451	Q658P3
TPRARARRLWLLLRT	WDR97	61	A6NE52
IRRRLIQRRWGLPRR	SPATA31D1	691	Q6ZQQ2
RRCPPLLRGLVQRWR	ZDHHC16	26	Q969W1
RALLLWGRRLRPLLR	TRAP1	6	Q12931
LICRGACRLFWPRSR	TLCD3B	251	Q71RH2
PRRLLERPWRFRGCL	nan	66	Q8N1Y9
RLRELCHQWLRPERR	ZNF202	66	O95125
VRAARLLLRRCPLWG	TRPM4	636	Q8TD43
RRRPALGWLARLLRS	ZFPL1	236	O95159