Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncalcium ion binding

LRP1 LRP2 SNED1 EYS FAT1 THBS3 FBLN5 STAB2 NOTCH1 JAG1 NOTCH3 NOTCH4 SLIT1 ITPR1

2.44e-127493214GO:0005509
GeneOntologyMolecularFunctionNotch binding

SNED1 NOTCH1 JAG1 NOTCH4

9.29e-0827324GO:0005112
GeneOntologyMolecularFunctionlow-density lipoprotein particle receptor activity

LRP1 LRP2 STAB2

2.06e-0616323GO:0005041
GeneOntologyMolecularFunctionlipoprotein particle receptor activity

LRP1 LRP2 STAB2

4.88e-0621323GO:0030228
GeneOntologyMolecularFunctionstructural molecule activity

LAMA2 LAMC2 LAMC3 THBS3 FBLN5 KRT31 KRT33A KRT33B JAG1

7.47e-06891329GO:0005198
GeneOntologyMolecularFunctionglycosaminoglycan binding

LAMC2 THBS3 STAB2 SLIT1 CEMIP

6.28e-05268325GO:0005539
GeneOntologyMolecularFunctionclathrin heavy chain binding

LRP1 CEMIP

1.63e-0412322GO:0032050
GeneOntologyMolecularFunctionextracellular matrix structural constituent

LAMA2 LAMC2 THBS3 FBLN5

2.23e-04188324GO:0005201
GeneOntologyMolecularFunctioncargo receptor activity

LRP1 LRP2 STAB2

3.38e-0485323GO:0038024
GeneOntologyMolecularFunctionscavenger receptor activity

LRP1 STAB2

8.52e-0427322GO:0005044
GeneOntologyMolecularFunctionheparan sulfate proteoglycan binding

LRP1 SLIT1

9.83e-0429322GO:0043395
GeneOntologyMolecularFunctionhyaluronic acid binding

STAB2 CEMIP

9.83e-0429322GO:0005540
GeneOntologyMolecularFunctionsulfur compound binding

LRP1 LAMC2 THBS3 SLIT1

1.69e-03323324GO:1901681
GeneOntologyMolecularFunctionlipoprotein particle receptor binding

LRP1 LRP2

1.78e-0339322GO:0070325
GeneOntologyMolecularFunctionproteoglycan binding

LRP1 SLIT1

3.02e-0351322GO:0043394
GeneOntologyMolecularFunctionheparin binding

LAMC2 THBS3 SLIT1

3.54e-03192323GO:0008201
GeneOntologyMolecularFunctionclathrin binding

LRP1 CEMIP

4.57e-0363322GO:0030276
GeneOntologyBiologicalProcessartery morphogenesis

LRP1 LRP2 NOTCH1 JAG1 NOTCH3 NOTCH4

5.51e-0992326GO:0048844
GeneOntologyBiologicalProcessaxon guidance

LRP1 LRP2 LAMA2 LAMC2 LAMC3 NOTCH1 NOTCH3 SLIT1

9.50e-09285328GO:0007411
GeneOntologyBiologicalProcessneuron projection guidance

LRP1 LRP2 LAMA2 LAMC2 LAMC3 NOTCH1 NOTCH3 SLIT1

9.77e-09286328GO:0097485
GeneOntologyBiologicalProcessartery development

LRP1 LRP2 NOTCH1 JAG1 NOTCH3 NOTCH4

5.07e-08133326GO:0060840
GeneOntologyBiologicalProcesscell morphogenesis

LRP1 LRP2 LAMA2 LAMC2 LAMC3 FAT1 NOTCH1 ADAM7 NOTCH3 NOTCH4 SLIT1 ITPR1

1.03e-0711943212GO:0000902
GeneOntologyBiologicalProcessaorta development

LRP1 LRP2 NOTCH1 JAG1 NOTCH4

1.43e-0780325GO:0035904
GeneOntologyBiologicalProcessaorta morphogenesis

LRP1 NOTCH1 JAG1 NOTCH4

4.64e-0741324GO:0035909
GeneOntologyBiologicalProcessaxonogenesis

LRP1 LRP2 LAMA2 LAMC2 LAMC3 NOTCH1 NOTCH3 SLIT1

1.80e-06566328GO:0007409
GeneOntologyBiologicalProcessaxon development

LRP1 LRP2 LAMA2 LAMC2 LAMC3 NOTCH1 NOTCH3 SLIT1

4.58e-06642328GO:0061564
GeneOntologyBiologicalProcessanimal organ morphogenesis

LRP2 LAMA2 LAMC2 LAMC3 FAT1 THBS3 NOTCH1 JAG1 SLIT1 ITPR1

1.39e-0512693210GO:0009887
GeneOntologyBiologicalProcesspositive regulation of aorta morphogenesis

NOTCH1 NOTCH4

1.40e-054322GO:1903849
GeneOntologyBiologicalProcesscell morphogenesis involved in neuron differentiation

LRP1 LRP2 LAMA2 LAMC2 LAMC3 NOTCH1 NOTCH3 SLIT1

1.40e-05748328GO:0048667
GeneOntologyBiologicalProcessneuron projection morphogenesis

LRP1 LRP2 LAMA2 LAMC2 LAMC3 NOTCH1 NOTCH3 SLIT1

2.31e-05802328GO:0048812
GeneOntologyBiologicalProcesschemoattraction of axon

LRP1 LRP2

2.33e-055322GO:0061642
GeneOntologyBiologicalProcesspositive regulation of lysosomal protein catabolic process

LRP1 LRP2

2.33e-055322GO:1905167
GeneOntologyBiologicalProcessblood vessel morphogenesis

LRP1 LRP2 FBLN5 STAB2 NOTCH1 JAG1 NOTCH3 NOTCH4

2.64e-05817328GO:0048514
GeneOntologyBiologicalProcessplasma membrane bounded cell projection morphogenesis

LRP1 LRP2 LAMA2 LAMC2 LAMC3 NOTCH1 NOTCH3 SLIT1

2.69e-05819328GO:0120039
GeneOntologyBiologicalProcesscell projection morphogenesis

LRP1 LRP2 LAMA2 LAMC2 LAMC3 NOTCH1 NOTCH3 SLIT1

2.86e-05826328GO:0048858
GeneOntologyBiologicalProcesscell-substrate adhesion

LRP1 SNED1 THBS3 FBLN5 NOTCH1 JAG1

3.48e-05410326GO:0031589
GeneOntologyBiologicalProcessregulation of aorta morphogenesis

NOTCH1 NOTCH4

3.48e-056322GO:1903847
GeneOntologyBiologicalProcessinhibition of neuroepithelial cell differentiation

NOTCH1 JAG1

3.48e-056322GO:0002085
GeneOntologyBiologicalProcesspulmonary artery morphogenesis

LRP2 JAG1

3.48e-056322GO:0061156
GeneOntologyBiologicalProcessepithelial cell differentiation

FAT1 KRT31 KRT33A KRT33B NOTCH1 ADAM7 JAG1 NOTCH4

4.14e-05870328GO:0030855
GeneOntologyBiologicalProcesspositive regulation of protein catabolic process in the vacuole

LRP1 LRP2

4.87e-057322GO:1904352
GeneOntologyBiologicalProcesspositive regulation of transcription of Notch receptor target

NOTCH1 NOTCH4

4.87e-057322GO:0007221
GeneOntologyBiologicalProcesscardiac septum development

LRP1 LRP2 NOTCH1 JAG1

5.32e-05134324GO:0003279
GeneOntologyBiologicalProcessepithelial cell development

FAT1 NOTCH1 ADAM7 JAG1 NOTCH4

5.49e-05269325GO:0002064
GeneOntologyBiologicalProcesscell-matrix adhesion

LRP1 SNED1 THBS3 FBLN5 JAG1

5.58e-05270325GO:0007160
GeneOntologyBiologicalProcessepithelial cell morphogenesis

FAT1 ADAM7 NOTCH4

5.95e-0549323GO:0003382
GeneOntologyBiologicalProcessblood vessel development

LRP1 LRP2 FBLN5 STAB2 NOTCH1 JAG1 NOTCH3 NOTCH4

6.58e-05929328GO:0001568
GeneOntologyBiologicalProcesspositive regulation of artery morphogenesis

NOTCH1 NOTCH4

8.34e-059322GO:1905653
GeneOntologyBiologicalProcesspositive regulation of cardiac epithelial to mesenchymal transition

NOTCH1 JAG1

8.34e-059322GO:0062043
GeneOntologyBiologicalProcessvasculature development

LRP1 LRP2 FBLN5 STAB2 NOTCH1 JAG1 NOTCH3 NOTCH4

8.85e-05969328GO:0001944
GeneOntologyBiologicalProcesscoronary artery morphogenesis

LRP2 NOTCH1

1.04e-0410322GO:0060982
GeneOntologyBiologicalProcessnegative regulation of cell-cell adhesion mediated by cadherin

NOTCH1 NOTCH4

1.04e-0410322GO:2000048
GeneOntologyBiologicalProcessdistal tubule development

NOTCH1 JAG1

1.04e-0410322GO:0072017
GeneOntologyBiologicalProcessneuron projection development

LRP1 LRP2 LAMA2 LAMC2 LAMC3 NOTCH1 NOTCH3 SLIT1 ITPR1

1.04e-041285329GO:0031175
GeneOntologyBiologicalProcessregulation of locomotion

LRP1 LAMA2 LAMC2 FAT1 NOTCH1 ADAM7 JAG1 SLIT1 CEMIP

1.33e-041327329GO:0040012
GeneOntologyBiologicalProcessregulation of endothelial cell differentiation

NOTCH1 JAG1 NOTCH4

1.52e-0467323GO:0045601
GeneOntologyBiologicalProcessregulation of lysosomal protein catabolic process

LRP1 LRP2

1.52e-0412322GO:1905165
GeneOntologyBiologicalProcessnegative regulation of epithelial cell differentiation

NOTCH1 JAG1 NOTCH4

1.66e-0469323GO:0030857
GeneOntologyBiologicalProcessvenous blood vessel morphogenesis

NOTCH1 NOTCH4

1.80e-0413322GO:0048845
GeneOntologyBiologicalProcesstube development

LRP1 LRP2 FBLN5 STAB2 NOTCH1 ADAM7 JAG1 NOTCH3 NOTCH4

2.03e-041402329GO:0035295
GeneOntologyBiologicalProcessnegative regulation of cell-substrate adhesion

LRP1 NOTCH1 JAG1

2.04e-0474323GO:0010812
GeneOntologyBiologicalProcessregulation of protein catabolic process in the vacuole

LRP1 LRP2

2.10e-0414322GO:1904350
GeneOntologyBiologicalProcessregulation of cardiac epithelial to mesenchymal transition

NOTCH1 JAG1

2.10e-0414322GO:0062042
GeneOntologyBiologicalProcessintermediate filament organization

KRT31 KRT33A KRT33B

2.12e-0475323GO:0045109
GeneOntologyBiologicalProcessglomerulus development

NOTCH1 JAG1 NOTCH3

2.30e-0477323GO:0032835
GeneOntologyBiologicalProcessnegative regulation of endothelial cell differentiation

JAG1 NOTCH4

2.42e-0415322GO:0045602
GeneOntologyBiologicalProcessregulation of timing of cell differentiation

NOTCH1 JAG1

2.42e-0415322GO:0048505
GeneOntologyBiologicalProcesstube morphogenesis

LRP1 LRP2 FBLN5 STAB2 NOTCH1 JAG1 NOTCH3 NOTCH4

2.48e-041125328GO:0035239
GeneOntologyBiologicalProcessnegative regulation of cell adhesion molecule production

NOTCH1 NOTCH4

2.76e-0416322GO:0060354
GeneOntologyBiologicalProcessneuroendocrine cell differentiation

NOTCH1 JAG1

2.76e-0416322GO:0061101
GeneOntologyBiologicalProcessneuron development

LRP1 LRP2 LAMA2 LAMC2 LAMC3 NOTCH1 NOTCH3 SLIT1 ITPR1

2.79e-041463329GO:0048666
GeneOntologyBiologicalProcesscoronary vasculature development

LRP1 LRP2 NOTCH1

2.86e-0483323GO:0060976
GeneOntologyBiologicalProcessepithelium development

LRP2 FAT1 KRT31 KRT33A KRT33B NOTCH1 ADAM7 JAG1 NOTCH4

2.88e-041469329GO:0060429
GeneOntologyBiologicalProcessregulation of extracellular matrix organization

LRP1 LAMA2 NOTCH1

2.97e-0484323GO:1903053
GeneOntologyBiologicalProcessNotch signaling pathway

NOTCH1 JAG1 NOTCH3 NOTCH4

3.00e-04210324GO:0007219
GeneOntologyBiologicalProcesscardiac chamber development

LRP1 LRP2 NOTCH1 JAG1

3.11e-04212324GO:0003205
GeneOntologyBiologicalProcessregulation of artery morphogenesis

NOTCH1 NOTCH4

3.13e-0417322GO:1905651
GeneOntologyBiologicalProcessregulation of development, heterochronic

NOTCH1 JAG1

3.13e-0417322GO:0040034
GeneOntologyBiologicalProcesscardiac ventricle morphogenesis

LRP2 NOTCH1 JAG1

3.40e-0488323GO:0003208
GeneOntologyBiologicalProcesshyaluronan catabolic process

STAB2 CEMIP

3.51e-0418322GO:0030214
GeneOntologyBiologicalProcesscardiac septum morphogenesis

LRP2 NOTCH1 JAG1

3.52e-0489323GO:0060411
GeneOntologyBiologicalProcessoutflow tract morphogenesis

LRP2 NOTCH1 JAG1

4.13e-0494323GO:0003151
GeneOntologyBiologicalProcessnegative regulation of neuron differentiation

NOTCH1 JAG1 NOTCH3

4.13e-0494323GO:0045665
GeneOntologyBiologicalProcesspulmonary valve morphogenesis

NOTCH1 JAG1

4.35e-0420322GO:0003184
GeneOntologyBiologicalProcessvenous blood vessel development

NOTCH1 NOTCH4

4.35e-0420322GO:0060841
GeneOntologyBiologicalProcessresponse to muramyl dipeptide

NOTCH1 JAG1

4.81e-0421322GO:0032495
GeneOntologyBiologicalProcesscardiac right ventricle morphogenesis

NOTCH1 JAG1

4.81e-0421322GO:0003215
GeneOntologyBiologicalProcessregulation of cell-cell adhesion mediated by cadherin

NOTCH1 NOTCH4

4.81e-0421322GO:2000047
GeneOntologyBiologicalProcessregulation of embryonic development

LAMA2 NOTCH1 JAG1

4.81e-0499323GO:0045995
GeneOntologyBiologicalProcessintermediate filament cytoskeleton organization

KRT31 KRT33A KRT33B

4.81e-0499323GO:0045104
GeneOntologyBiologicalProcessintermediate filament-based process

KRT31 KRT33A KRT33B

4.95e-04100323GO:0045103
GeneOntologyBiologicalProcessgliogenesis

LRP1 LRP2 LAMA2 LAMC3 NOTCH1

5.13e-04435325GO:0042063
GeneOntologyBiologicalProcessastrocyte differentiation

LRP1 LAMC3 NOTCH1

5.71e-04105323GO:0048708
GeneOntologyBiologicalProcessregulation of cell adhesion molecule production

NOTCH1 NOTCH4

5.78e-0423322GO:0060353
GeneOntologyBiologicalProcesspositive regulation of muscle cell differentiation

LAMA2 NOTCH1 NOTCH4

5.87e-04106323GO:0051149
GeneOntologyBiologicalProcessregulation of cell motility

LRP1 LAMA2 LAMC2 FAT1 NOTCH1 ADAM7 JAG1 CEMIP

5.92e-041280328GO:2000145
GeneOntologyBiologicalProcessregeneration

LRP1 EYS NOTCH1 ITPR1

5.98e-04252324GO:0031099
GeneOntologyBiologicalProcesspulmonary valve development

NOTCH1 JAG1

6.30e-0424322GO:0003177
GeneOntologyBiologicalProcesslysosomal protein catabolic process

LRP1 LRP2

6.30e-0424322GO:1905146
GeneOntologyBiologicalProcesstranscytosis

LRP1 LRP2

6.30e-0424322GO:0045056
GeneOntologyBiologicalProcessangiogenesis

FBLN5 STAB2 NOTCH1 JAG1 NOTCH3 NOTCH4

6.76e-04708326GO:0001525
GeneOntologyBiologicalProcessregulation of Notch signaling pathway

NOTCH1 JAG1 NOTCH4

7.26e-04114323GO:0008593
GeneOntologyBiologicalProcesscell adhesion molecule production

NOTCH1 NOTCH4

7.40e-0426322GO:0060352
GeneOntologyBiologicalProcesspositive regulation of cell motility

LRP1 LAMC2 FAT1 NOTCH1 ADAM7 CEMIP

7.66e-04725326GO:2000147
GeneOntologyBiologicalProcesslipoprotein transport

LRP1 LRP2

8.60e-0428322GO:0042953
GeneOntologyBiologicalProcessprotein catabolic process in the vacuole

LRP1 LRP2

8.60e-0428322GO:0007039
GeneOntologyBiologicalProcesspositive regulation of smooth muscle cell differentiation

NOTCH1 NOTCH4

8.60e-0428322GO:0051152
GeneOntologyBiologicalProcesspositive regulation of locomotion

LRP1 LAMC2 FAT1 NOTCH1 ADAM7 CEMIP

8.64e-04742326GO:0040017
GeneOntologyBiologicalProcesslipoprotein localization

LRP1 LRP2

9.22e-0429322GO:0044872
GeneOntologyBiologicalProcessglomerulus vasculature development

NOTCH1 NOTCH3

9.87e-0430322GO:0072012
GeneOntologyBiologicalProcesskidney vasculature development

NOTCH1 NOTCH3

1.05e-0331322GO:0061440
GeneOntologyBiologicalProcessrenal system vasculature development

NOTCH1 NOTCH3

1.05e-0331322GO:0061437
GeneOntologyBiologicalProcessglycosaminoglycan catabolic process

STAB2 CEMIP

1.12e-0332322GO:0006027
GeneOntologyBiologicalProcessnegative regulation of stem cell differentiation

NOTCH1 JAG1

1.19e-0333322GO:2000737
GeneOntologyBiologicalProcesscoronary vasculature morphogenesis

LRP2 NOTCH1

1.27e-0334322GO:0060977
GeneOntologyBiologicalProcesscirculatory system development

LRP1 LRP2 FBLN5 STAB2 NOTCH1 JAG1 NOTCH3 NOTCH4

1.29e-031442328GO:0072359
GeneOntologyBiologicalProcesspositive regulation of vascular associated smooth muscle cell migration

LRP1 FAT1

1.42e-0336322GO:1904754
GeneOntologyCellularComponentextracellular matrix

LAMA2 SNED1 LAMC2 LAMC3 EYS THBS3 FBLN5 FCGBP

4.86e-06656328GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

LAMA2 SNED1 LAMC2 LAMC3 EYS THBS3 FBLN5 FCGBP

4.98e-06658328GO:0030312
GeneOntologyCellularComponentcollagen-containing extracellular matrix

LAMA2 LAMC2 LAMC3 EYS THBS3 FBLN5

1.34e-04530326GO:0062023
GeneOntologyCellularComponentapical part of cell

LRP1 LRP2 FAT1 NOTCH1 ADAM7 JAG1

2.43e-04592326GO:0045177
GeneOntologyCellularComponentclathrin-coated pit

LRP1 LRP2 CEMIP

2.47e-0480323GO:0005905
GeneOntologyCellularComponentbasement membrane

LAMA2 LAMC2 LAMC3

8.50e-04122323GO:0005604
GeneOntologyCellularComponentreceptor complex

LRP1 LRP2 TAS1R3 NOTCH1 NOTCH3

1.76e-03581325GO:0043235
GeneOntologyCellularComponentaxonal growth cone

LRP1 LRP2

2.16e-0345322GO:0044295
GeneOntologyCellularComponentendocytic vesicle

LRP1 LRP2 STAB2 CEMIP

2.68e-03384324GO:0030139
GeneOntologyCellularComponentendocytic vesicle membrane

LRP1 LRP2 STAB2

4.11e-03212323GO:0030666
GeneOntologyCellularComponentintermediate filament

KRT31 KRT33A KRT33B

4.97e-03227323GO:0005882
GeneOntologyCellularComponentclathrin-coated vesicle

LRP1 LRP2 CEMIP

5.60e-03237323GO:0030136
GeneOntologyCellularComponentasymmetric synapse

LRP1 ELAVL2 NOTCH1 ITPR1

5.80e-03477324GO:0032279
GeneOntologyCellularComponentcell surface

LRP1 LRP2 STAB2 NOTCH1 NOTCH3 NOTCH4

6.13e-031111326GO:0009986
GeneOntologyCellularComponentapical plasma membrane

LRP2 FAT1 NOTCH1 JAG1

6.24e-03487324GO:0016324
GeneOntologyCellularComponentintermediate filament cytoskeleton

KRT31 KRT33A KRT33B

7.46e-03263323GO:0045111
GeneOntologyCellularComponentneuron to neuron synapse

LRP1 ELAVL2 NOTCH1 ITPR1

8.00e-03523324GO:0098984
MousePhenoopisthotonus

LAMA2 ITPR1

3.58e-055272MP:0002880
MousePhenoabnormal basal lamina morphology

LAMA2 LAMC2

5.36e-056272MP:0004273
MousePhenoabsent vestibular hair cells

LAMA2 JAG1

9.99e-058272MP:0004325
DomainEGF

LRP1 LRP2 LAMA2 SNED1 LAMC2 LAMC3 EYS FAT1 THBS3 FBLN5 STAB2 FCGBP NOTCH1 JAG1 NOTCH3 NOTCH4 SLIT1

1.32e-242353217SM00181
DomainEGF-like_dom

LRP1 LRP2 LAMA2 SNED1 LAMC2 LAMC3 EYS FAT1 THBS3 FBLN5 STAB2 FCGBP NOTCH1 JAG1 NOTCH3 NOTCH4 SLIT1

3.63e-242493217IPR000742
DomainEGF_1

LRP1 LRP2 LAMA2 SNED1 LAMC2 LAMC3 EYS FAT1 THBS3 FBLN5 STAB2 NOTCH1 JAG1 NOTCH3 NOTCH4 SLIT1

4.49e-222553216PS00022
DomainEGF-like_CS

LRP1 LRP2 LAMA2 SNED1 LAMC2 LAMC3 EYS FAT1 THBS3 FBLN5 STAB2 NOTCH1 JAG1 NOTCH3 NOTCH4 SLIT1

6.56e-222613216IPR013032
DomainEGF_2

LRP1 LRP2 LAMA2 SNED1 LAMC2 LAMC3 EYS FAT1 THBS3 FBLN5 STAB2 NOTCH1 JAG1 NOTCH3 NOTCH4 SLIT1

8.40e-222653216PS01186
DomainGrowth_fac_rcpt_

LRP1 LRP2 LAMC2 LAMC3 EYS FAT1 THBS3 FBLN5 STAB2 NOTCH1 JAG1 NOTCH3 NOTCH4 SLIT1

1.84e-211563214IPR009030
DomainEGF_CA

LRP1 LRP2 SNED1 EYS FAT1 THBS3 FBLN5 STAB2 NOTCH1 JAG1 NOTCH3 NOTCH4 SLIT1

6.39e-211223213SM00179
DomainEGF-like_Ca-bd_dom

LRP1 LRP2 SNED1 EYS FAT1 THBS3 FBLN5 STAB2 NOTCH1 JAG1 NOTCH3 NOTCH4 SLIT1

7.97e-211243213IPR001881
DomainEGF_Ca-bd_CS

LRP1 LRP2 SNED1 EYS FAT1 THBS3 FBLN5 NOTCH1 JAG1 NOTCH3 NOTCH4 SLIT1

3.95e-20973212IPR018097
DomainEGF_CA

LRP1 LRP2 SNED1 EYS FAT1 THBS3 FBLN5 NOTCH1 JAG1 NOTCH3 NOTCH4 SLIT1

5.11e-20993212PS01187
DomainEGF-type_Asp/Asn_hydroxyl_site

LRP1 LRP2 SNED1 EYS FAT1 FBLN5 NOTCH1 JAG1 NOTCH3 NOTCH4 SLIT1

1.35e-171063211IPR000152
DomainEGF_3

LRP1 LRP2 SNED1 EYS FAT1 THBS3 FBLN5 STAB2 NOTCH1 JAG1 NOTCH3 NOTCH4 SLIT1

3.99e-172353213PS50026
DomainEGF

LRP1 LRP2 SNED1 EYS FAT1 STAB2 NOTCH1 JAG1 NOTCH3 NOTCH4 SLIT1

9.66e-171263211PF00008
DomainASX_HYDROXYL

LRP1 LRP2 SNED1 EYS FAT1 FBLN5 NOTCH1 JAG1 NOTCH3 NOTCH4

7.14e-161003210PS00010
DomainEGF_CA

LRP1 LRP2 FAT1 THBS3 FBLN5 NOTCH1 JAG1 NOTCH3 NOTCH4

1.56e-1486329PF07645
DomainhEGF

SNED1 EYS NOTCH1 JAG1 NOTCH3 NOTCH4 SLIT1

2.47e-1428327PF12661
DomainNOD

NOTCH1 NOTCH3 NOTCH4

1.83e-084323PF06816
DomainNotch

NOTCH1 NOTCH3 NOTCH4

1.83e-084323IPR008297
DomainNODP

NOTCH1 NOTCH3 NOTCH4

1.83e-084323PF07684
DomainNotch_NODP_dom

NOTCH1 NOTCH3 NOTCH4

1.83e-084323IPR011656
DomainNotch_NOD_dom

NOTCH1 NOTCH3 NOTCH4

1.83e-084323IPR010660
DomainNOD

NOTCH1 NOTCH3 NOTCH4

1.83e-084323SM01338
DomainNODP

NOTCH1 NOTCH3 NOTCH4

1.83e-084323SM01339
DomainLNR

NOTCH1 NOTCH3 NOTCH4

4.56e-085323PS50258
DomainLaminin_G

LAMA2 EYS FAT1 THBS3 SLIT1

4.57e-0858325IPR001791
DomainEGF_extracell

LRP2 STAB2 NOTCH1 JAG1 NOTCH3

5.44e-0860325IPR013111
DomainEGF_2

LRP2 STAB2 NOTCH1 JAG1 NOTCH3

5.44e-0860325PF07974
DomainNotch_dom

NOTCH1 NOTCH3 NOTCH4

1.59e-077323IPR000800
DomainNotch

NOTCH1 NOTCH3 NOTCH4

1.59e-077323PF00066
DomainNL

NOTCH1 NOTCH3 NOTCH4

1.59e-077323SM00004
DomainEGF_LAM_2

LAMA2 LAMC2 LAMC3 STAB2

1.88e-0730324PS50027
DomainEGF_LAM_1

LAMA2 LAMC2 LAMC3 STAB2

1.88e-0730324PS01248
DomainLAMININ_IVA

LAMA2 LAMC2 LAMC3

2.54e-078323PS51115
DomainLaminin_B

LAMA2 LAMC2 LAMC3

2.54e-078323PF00052
DomainLamB

LAMA2 LAMC2 LAMC3

2.54e-078323SM00281
DomainLaminin_IV

LAMA2 LAMC2 LAMC3

2.54e-078323IPR000034
DomainEGF_Lam

LAMA2 LAMC2 LAMC3 STAB2

3.58e-0735324SM00180
DomainLAM_G_DOMAIN

LAMA2 EYS FAT1 SLIT1

5.03e-0738324PS50025
DomainLaminin_EGF

LAMA2 LAMC2 LAMC3 STAB2

5.03e-0738324IPR002049
Domain-

LAMA2 EYS FAT1 THBS3 SLIT1

5.53e-07953252.60.120.200
DomainLaminin_G_2

LAMA2 EYS FAT1 SLIT1

6.21e-0740324PF02210
DomainFol_N

SNED1 FCGBP SLIT1

7.47e-0711323IPR003645
DomainFOLN

SNED1 FCGBP SLIT1

7.47e-0711323SM00274
DomainLamG

LAMA2 EYS FAT1 SLIT1

9.18e-0744324SM00282
DomainDUF3454

NOTCH1 NOTCH3

8.52e-063322PF11936
DomainDUF3454_notch

NOTCH1 NOTCH3

8.52e-063322IPR024600
DomainDUF3454

NOTCH1 NOTCH3

8.52e-063322SM01334
DomaincEGF

LRP1 LRP2 FBLN5

1.16e-0526323IPR026823
DomaincEGF

LRP1 LRP2 FBLN5

1.16e-0526323PF12662
DomainLaminin_EGF

LAMA2 LAMC2 LAMC3

2.88e-0535323PF00053
DomainConA-like_dom

LAMA2 EYS FAT1 THBS3 SLIT1

3.29e-05219325IPR013320
DomainKeratin_I

KRT31 KRT33A KRT33B

5.77e-0544323IPR002957
DomainLaminin_G_1

LAMA2 EYS

1.55e-0411322PF00054
DomainIntermediate_filament_CS

KRT31 KRT33A KRT33B

1.69e-0463323IPR018039
DomainFilament

KRT31 KRT33A KRT33B

2.41e-0471323SM01391
DomainIF

KRT31 KRT33A KRT33B

2.51e-0472323PS00226
DomainLdl_recept_b

LRP1 LRP2

2.55e-0414322PF00058
DomainLDLRB

LRP1 LRP2

2.55e-0414322PS51120
DomainTIL_dom

LRP2 FCGBP

2.55e-0414322IPR002919
DomainFilament

KRT31 KRT33A KRT33B

2.62e-0473323PF00038
DomainLY

LRP1 LRP2

2.94e-0415322SM00135
DomainLDLR_classB_rpt

LRP1 LRP2

2.94e-0415322IPR000033
DomainIF

KRT31 KRT33A KRT33B

2.95e-0476323IPR001664
DomainLAMININ_NTER

LAMA2 LAMC3

3.36e-0416322PS51117
DomainLaminin_N

LAMA2 LAMC3

3.36e-0416322PF00055
DomainLaminin_N

LAMA2 LAMC3

3.36e-0416322IPR008211
DomainLamNT

LAMA2 LAMC3

3.36e-0416322SM00136
DomainVWC_out

FCGBP JAG1

4.78e-0419322SM00215
DomainVWC

FCGBP JAG1

1.92e-0338322SM00214
Domain-

LRP1 LRP2

2.03e-03393222.120.10.30
DomainLDLR_class-A_CS

LRP1 LRP2

2.13e-0340322IPR023415
DomainVWF_dom

FCGBP JAG1

2.35e-0342322IPR001007
DomainLdl_recept_a

LRP1 LRP2

2.69e-0345322PF00057
Domain-

LRP1 LRP2

2.81e-03463224.10.400.10
Domain6-blade_b-propeller_TolB-like

LRP1 LRP2

2.81e-0346322IPR011042
DomainLDLRA_1

LRP1 LRP2

3.05e-0348322PS01209
DomainLDrepeatLR_classA_rpt

LRP1 LRP2

3.18e-0349322IPR002172
DomainLDLa

LRP1 LRP2

3.18e-0349322SM00192
DomainLDLRA_2

LRP1 LRP2

3.18e-0349322PS50068
PathwayKEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00380

NOTCH1 JAG1 NOTCH3 NOTCH4

7.07e-0912294M47532
PathwayKEGG_MEDICUS_REFERENCE_NOTCH_SIGNALING_PATHWAY

NOTCH1 JAG1 NOTCH3 NOTCH4

1.02e-0813294M47423
PathwayREACTOME_DEFECTIVE_LFNG_CAUSES_SCDO3

NOTCH1 NOTCH3 NOTCH4

7.81e-085293M27411
PathwayREACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI

NOTCH1 NOTCH3 NOTCH4

7.81e-085293MM14733
PathwayREACTOME_PRE_NOTCH_PROCESSING_IN_THE_ENDOPLASMIC_RETICULUM

NOTCH1 NOTCH3 NOTCH4

1.56e-076293M27068
PathwayWP_CANONICAL_AND_NONCANONICAL_NOTCH_SIGNALING

NOTCH1 JAG1 NOTCH3 NOTCH4

2.45e-0727294M39545
PathwayREACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING

NOTCH1 NOTCH3 NOTCH4

2.72e-077293MM14734
PathwayWP_NEOVASCULARIZATION_PROCESSES

NOTCH1 JAG1 NOTCH3 NOTCH4

9.10e-0737294M39506
PathwayREACTOME_SIGNALING_BY_NOTCH

NOTCH1 JAG1 NOTCH3 NOTCH4

1.13e-0639294MM14604
PathwayKEGG_MEDICUS_REFERENCE_NOTCH_PROTEOLYTIC_ACTIVATION

NOTCH1 NOTCH3 NOTCH4

1.28e-0611293M47865
PathwayKEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00381

NOTCH1 NOTCH3 NOTCH4

1.70e-0612293M47533
PathwayWP_NOTCH_SIGNALING_WP268

NOTCH1 JAG1 NOTCH3 NOTCH4

2.03e-0645294M39571
PathwayKEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00382

NOTCH1 NOTCH3 NOTCH4

2.21e-0613293M47534
PathwayWP_NOTCH_SIGNALING_PATHWAY

NOTCH1 JAG1 NOTCH3 NOTCH4

2.22e-0646294MM15971
PathwayKEGG_NOTCH_SIGNALING_PATHWAY

NOTCH1 JAG1 NOTCH3 NOTCH4

2.42e-0647294M7946
PathwayKEGG_MEDICUS_VARIANT_NOTCH_OVEREXPRESSION_TO_NOTCH_SIGNALING_PATHWAY

NOTCH1 JAG1 NOTCH4

4.31e-0616293M47424
PathwayPID_NOTCH_PATHWAY

NOTCH1 JAG1 NOTCH3 NOTCH4

6.08e-0659294M17
PathwayREACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI

NOTCH1 NOTCH3 NOTCH4

6.26e-0618293M614
PathwayWP_NOTCH_SIGNALING_WP61

NOTCH1 JAG1 NOTCH3 NOTCH4

6.95e-0661294M39540
PathwayREACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY

NOTCH1 NOTCH3 NOTCH4

1.35e-0523293MM14954
PathwayKEGG_DORSO_VENTRAL_AXIS_FORMATION

NOTCH1 NOTCH3 NOTCH4

1.54e-0524293M11190
PathwayWP_DELTANOTCH_SIGNALING_PATHWAY

NOTCH1 JAG1 NOTCH3 NOTCH4

2.26e-0582294MM15922
PathwayREACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY

NOTCH1 NOTCH3 NOTCH4

2.48e-0528293M6177
PathwayKEGG_ECM_RECEPTOR_INTERACTION

LAMA2 LAMC2 LAMC3 THBS3

2.49e-0584294M7098
PathwayREACTOME_MET_ACTIVATES_PTK2_SIGNALING

LAMA2 LAMC2 LAMC3

3.06e-0530293M27772
PathwayREACTOME_LAMININ_INTERACTIONS

LAMA2 LAMC2 LAMC3

3.06e-0530293M27216
PathwayWP_OSX_AND_MIRNAS_IN_TOOTH_DEVELOPMENT

NOTCH1 NOTCH3 NOTCH4

4.49e-0534293M39390
PathwayWP_GENETIC_CAUSES_OF_PORTOSINUSOIDAL_VASCULAR_DISEASE

KCNN3 NOTCH1 NOTCH4

5.80e-0537293M45513
PathwayWP_CANCER_PATHWAYS

LAMA2 LAMC2 LAMC3 NOTCH1 JAG1 NOTCH3 NOTCH4

5.85e-05507297M48302
PathwayREACTOME_MET_PROMOTES_CELL_MOTILITY

LAMA2 LAMC2 LAMC3

7.92e-0541293M27778
PathwayREACTOME_SIGNALING_BY_NOTCH1_T_7_9_NOTCH1_M1580_K2555_TRANSLOCATION_MUTANT

NOTCH1 JAG1

8.53e-057292M27199
PathwayWP_OSTEOBLAST_DIFFERENTIATION_AND_RELATED_DISEASES

NOTCH1 JAG1 NOTCH3 NOTCH4

9.42e-05118294M39852
PathwayPID_A6B1_A6B4_INTEGRIN_PATHWAY

LAMA2 LAMC2 LAMC3

1.12e-0446293M239
PathwayREACTOME_SIGNALING_BY_NOTCH3

NOTCH1 JAG1 NOTCH3

1.35e-0449293M618
PathwayREACTOME_NOTCH4_ACTIVATION_AND_TRANSMISSION_OF_SIGNAL_TO_THE_NUCLEUS

JAG1 NOTCH4

2.22e-0411292M27882
PathwayPID_INTEGRIN4_PATHWAY

LAMA2 LAMC2

2.22e-0411292M158
PathwayREACTOME_NON_INTEGRIN_MEMBRANE_ECM_INTERACTIONS

LAMA2 LAMC2 LAMC3

2.36e-0459293M27218
PathwayWP_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_IN_COLORECTAL_CANCER

NOTCH1 JAG1 NOTCH3 NOTCH4

3.12e-04161294M39770
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

LAMA2 LAMC2 LAMC3 FBLN5 ICAM4

3.30e-04300295M610
PathwayREACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS

NOTCH1 NOTCH3 NOTCH4

3.59e-0468293M27303
PathwayREACTOME_RUNX3_REGULATES_NOTCH_SIGNALING

NOTCH1 JAG1

3.66e-0414292M27808
PathwayREACTOME_SIGNALING_BY_NOTCH1_HD_DOMAIN_MUTANTS_IN_CANCER

NOTCH1 JAG1

4.22e-0415292M27202
PathwayWP_PRIMARY_FOCAL_SEGMENTAL_GLOMERULOSCLEROSIS_FSGS

FAT1 NOTCH1 JAG1

4.24e-0472293M39403
PathwayWP_PRIMARY_FOCAL_SEGMENTAL_GLOMERULOSCLEROSIS_FSGS

FAT1 NOTCH1 JAG1

4.42e-0473293MM15906
PathwayREACTOME_HYALURONAN_METABOLISM

STAB2 CEMIP

5.45e-0417292M666
PathwayWP_AMPLIFICATION_AND_EXPANSION_OF_ONCOGENIC_PATHWAYS_AS_METASTATIC_TRAITS

NOTCH1 JAG1

5.45e-0417292M39443
PathwayREACTOME_HYALURONAN_METABOLISM

STAB2 CEMIP

5.45e-0417292MM14864
PathwayWP_NOTCH1_REGULATION_OF_ENDOTHELIAL_CELL_CALCIFICATION

NOTCH1 JAG1

5.45e-0417292M39389
PathwayWP_FOCAL_ADHESION

LAMA2 LAMC2 LAMC3 THBS3

5.49e-04187294MM15913
PathwayREACTOME_SIGNALING_BY_MET

LAMA2 LAMC2 LAMC3

5.57e-0479293M27643
PathwayREACTOME_SIGNALING_BY_NOTCH4

NOTCH1 JAG1 NOTCH4

6.21e-0482293M594
PathwayKEGG_SMALL_CELL_LUNG_CANCER

LAMA2 LAMC2 LAMC3

6.67e-0484293M3228
PathwayREACTOME_SIGNALING_BY_NOTCH3

JAG1 NOTCH3

6.84e-0419292MM15594
PathwayWP_FOCAL_ADHESION

LAMA2 LAMC2 LAMC3 THBS3

6.94e-04199294M39402
PathwayKEGG_FOCAL_ADHESION

LAMA2 LAMC2 LAMC3 THBS3

6.94e-04199294M7253
PathwayREACTOME_FORMATION_OF_THE_CORNIFIED_ENVELOPE

KRT31 KRT33A KRT33B

7.39e-0487293MM15351
PathwayREACTOME_NOTCH4_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION

NOTCH1 NOTCH4

7.59e-0420292M27881
PathwayWP_SMALL_CELL_LUNG_CANCER

LAMA2 LAMC2 LAMC3

9.84e-0496293M39834
PathwayWP_NEURAL_CREST_DIFFERENTIATION

NOTCH1 NOTCH3 NOTCH4

1.01e-0397293MM15926
PathwayWP_NEURAL_CREST_DIFFERENTIATION

NOTCH1 NOTCH3 NOTCH4

1.14e-03101293M39448
PathwayREACTOME_NOTCH3_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION

NOTCH1 NOTCH3

1.19e-0325292M27880
PathwayREACTOME_NOTCH3_ACTIVATION_AND_TRANSMISSION_OF_SIGNAL_TO_THE_NUCLEUS

JAG1 NOTCH3

1.19e-0325292M27879
PathwayREACTOME_SIGNALING_BY_NOTCH

NOTCH1 JAG1 NOTCH3 NOTCH4

1.52e-03246294M10189
PathwayWP_INFLAMMATORY_RESPONSE_PATHWAY

LAMC2 THBS3

1.72e-0330292M39641
PathwayWP_INFLAMMATORY_RESPONSE_PATHWAY

LAMC2 THBS3

1.72e-0330292MM15812
PathwayREACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING

NOTCH1 NOTCH3 NOTCH4

1.83e-03119293M607
PathwayREACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS

NOTCH1 JAG1

1.83e-0331292M592
PathwayWP_ALPHA_6_BETA_4_SIGNALING

LAMA2 LAMC2

2.07e-0333292M39503
PathwayREACTOME_FORMATION_OF_THE_CORNIFIED_ENVELOPE

KRT31 KRT33A KRT33B

2.30e-03129293M27649
PathwayREACTOME_DISEASES_OF_GLYCOSYLATION

NOTCH1 NOTCH3 NOTCH4

3.08e-03143293M27275
PathwayWP_FOCAL_ADHESION_PI3KAKTMTORSIGNALING

LAMA2 LAMC2 LAMC3 THBS3

3.21e-03302294M39719
PathwayREACTOME_KERATINIZATION

KRT31 KRT33A KRT33B

3.72e-03153293MM15343
PathwayWP_BREAST_CANCER_PATHWAY

NOTCH1 NOTCH3 NOTCH4

3.79e-03154293M39739
PathwayREACTOME_METABOLISM_OF_FAT_SOLUBLE_VITAMINS

LRP1 LRP2

3.83e-0345292MM15344
PathwayPID_DELTA_NP63_PATHWAY

HBP1 NOTCH1

4.17e-0347292M236
PathwayREACTOME_SIGNALING_BY_RECEPTOR_TYROSINE_KINASES

LAMA2 LAMC2 LAMC3 THBS3 ITPR1

4.21e-03532295M27870
PathwayWP_FOCAL_ADHESION_PI3KAKTMTOR_SIGNALING_PATHWAY

LAMA2 LAMC2 LAMC3 THBS3

4.22e-03326294MM15917
PathwayREACTOME_METABOLISM_OF_FAT_SOLUBLE_VITAMINS

LRP1 LRP2

4.35e-0348292M27642
PathwayWP_PI3KAKT_SIGNALING

LAMA2 LAMC2 LAMC3 THBS3

4.85e-03339294M39736
PathwayPID_TAP63_PATHWAY

HBP1 JAG1

5.47e-0354292M256
PathwayWP_NEUROGENESIS_REGULATION_IN_THE_OLFACTORY_EPITHELIUM

NOTCH1 JAG1

6.08e-0357292M48326
PathwayREACTOME_SIGNALING_BY_NOTCH1_PEST_DOMAIN_MUTANTS_IN_CANCER

NOTCH1 JAG1

6.29e-0358292M29616
PathwayWP_MARKERS_OF_KIDNEY_CELL_LINEAGE

NOTCH1 JAG1

6.50e-0359292M46460
PathwayREACTOME_BINDING_AND_UPTAKE_OF_LIGANDS_BY_SCAVENGER_RECEPTORS

LRP1 STAB2

6.72e-0360292MM14872
PathwayREACTOME_SENSORY_PERCEPTION

LRP1 LRP2 TAS1R3

6.80e-03190293MM15687
PathwayWP_ALPHA_6_BETA_4_INTEGRIN_SIGNALING_PATHWAY

LAMA2 LAMC2

8.08e-0366292MM15925
PathwayPID_INTEGRIN1_PATHWAY

LAMA2 LAMC2

8.08e-0366292M18
PathwayREACTOME_KERATINIZATION

KRT31 KRT33A KRT33B

9.79e-03217293M27640
PathwayWP_HEAD_AND_NECK_SQUAMOUS_CELL_CARCINOMA

FAT1 NOTCH1

1.01e-0274292M39857
PathwayWP_ALZHEIMERS_DISEASE

LRP1 ITPR1

1.01e-0274292MM15962
PathwayREACTOME_SIGNALING_BY_NOTCH1

NOTCH1 JAG1

1.01e-0274292M616
Pubmed

Functional redundancy of the Notch gene family during mouse embryogenesis: analysis of Notch gene expression in Notch3-deficient mice.

NOTCH1 JAG1 NOTCH3 NOTCH4

2.95e-12532415882997
Pubmed

Squamous odontogenic tumor of the mandible: a case report demonstrating immunoexpression of Notch1, 3, 4, Jagged1 and Delta1.

NOTCH1 JAG1 NOTCH3 NOTCH4

2.95e-12532420554499
Pubmed

A study on Notch signaling in human breast cancer.

NOTCH1 JAG1 NOTCH3 NOTCH4

8.84e-12632417822320
Pubmed

Characterization of Notch receptor expression in the developing mammalian heart and liver.

NOTCH1 JAG1 NOTCH3 NOTCH4

8.84e-12632412244553
Pubmed

Human ligands of the Notch receptor.

NOTCH1 JAG1 NOTCH3 NOTCH4

2.06e-11732410079256
Pubmed

The distribution of Notch receptors and their ligands during articular cartilage development.

NOTCH1 JAG1 NOTCH3 NOTCH4

2.06e-11732412846471
Pubmed

Cranial neural crest ablation of Jagged1 recapitulates the craniofacial phenotype of Alagille syndrome patients.

NOTCH1 JAG1 NOTCH3 NOTCH4

4.12e-11832422156581
Pubmed

Notch1 and Jagged1 expression by the developing pulmonary vasculature.

NOTCH1 JAG1 NOTCH3 NOTCH4

4.12e-11832412242716
Pubmed

Distinct expression patterns of notch family receptors and ligands during development of the mammalian inner ear.

NOTCH1 JAG1 NOTCH3 NOTCH4

4.12e-1183249858718
Pubmed

Dynamic expression patterns of the pudgy/spondylocostal dysostosis gene Dll3 in the developing nervous system.

NOTCH1 JAG1 NOTCH3 NOTCH4

7.41e-11932411118901
Pubmed

Notch1 signals through Jagged2 to regulate apoptosis in the apical ectodermal ridge of the developing limb bud.

NOTCH1 JAG1 NOTCH3 NOTCH4

7.41e-11932416245338
Pubmed

Spatiotemporal expression of Notch receptors and ligands in developing mouse placenta.

NOTCH1 JAG1 NOTCH3 NOTCH4

1.23e-101032423665443
Pubmed

Coexpression of Cux-1 and Notch signaling pathway components during kidney development.

NOTCH1 JAG1 NOTCH3 NOTCH4

1.94e-101132415499562
Pubmed

Localisation of members of the notch system and the differentiation of vibrissa hair follicles: receptors, ligands, and fringe modulators.

NOTCH1 JAG1 NOTCH3 NOTCH4

1.94e-101132410878608
Pubmed

A family of mammalian Fringe genes implicated in boundary determination and the Notch pathway.

NOTCH1 JAG1 NOTCH3 NOTCH4

1.94e-10113249187150
Pubmed

Notch-associated gene expression in embryonic and adult taste papillae and taste buds suggests a role in taste cell lineage decisions.

NOTCH1 JAG1 NOTCH3 NOTCH4

1.94e-101132412866128
Pubmed

Developmental expression of the Notch signaling pathway genes during mouse preimplantation development.

NOTCH1 JAG1 NOTCH3 NOTCH4

2.91e-101232415465494
Pubmed

Vascular expression of Notch pathway receptors and ligands is restricted to arterial vessels.

NOTCH1 JAG1 NOTCH3 NOTCH4

4.19e-101332411578869
Pubmed

Inhibition of notch1-dependent cardiomyogenesis leads to a dilated myopathy in the neonatal heart.

NOTCH1 JAG1 NOTCH3 NOTCH4

4.19e-101332420558824
Pubmed

Molecular Profiling of the Developing Lacrimal Gland Reveals Putative Role of Notch Signaling in Branching Morphogenesis.

NOTCH1 JAG1 NOTCH3 NOTCH4

5.87e-101432428192800
Pubmed

Math1 controls cerebellar granule cell differentiation by regulating multiple components of the Notch signaling pathway.

NOTCH1 JAG1 NOTCH3 NOTCH4

5.87e-101432414757642
Pubmed

Notch receptor expression in human brain arteriovenous malformations.

NOTCH1 NOTCH3 NOTCH4

7.07e-10332325846406
Pubmed

Characterization of Notch Signalling Pathway Members in Normal Prostate, Prostatic Intraepithelial Neoplasia (PIN) and Prostatic Adenocarcinoma.

NOTCH1 JAG1 NOTCH4

7.07e-10332326341090
Pubmed

Notch activation results in phenotypic and functional changes consistent with endothelial-to-mesenchymal transformation.

NOTCH1 JAG1 NOTCH4

7.07e-10332314988227
Pubmed

Unique patterns of Notch1, Notch4 and Jagged1 expression in ovarian vessels during folliculogenesis and corpus luteum formation.

NOTCH1 JAG1 NOTCH4

7.07e-10332315939383
Pubmed

Expression of Notch pathway genes in the embryonic mouse metanephros suggests a role in proximal tubule development.

NOTCH1 JAG1 NOTCH3 NOTCH4

8.00e-101532412971992
Pubmed

Expression of Notch pathway components in fetal and adult mouse small intestine.

NOTCH1 JAG1 NOTCH3 NOTCH4

1.07e-091632412617809
Pubmed

Notch gene expression during pancreatic organogenesis.

NOTCH1 JAG1 NOTCH3 NOTCH4

1.07e-091632410842072
Pubmed

An essential role for Notch in neural crest during cardiovascular development and smooth muscle differentiation.

NOTCH1 JAG1 NOTCH3 NOTCH4

1.07e-091632417273555
Pubmed

Gamma-secretase activation of notch signaling regulates the balance of proximal and distal fates in progenitor cells of the developing lung.

NOTCH1 JAG1 NOTCH3 NOTCH4

1.39e-091732418694942
Pubmed

Segmental expression of Notch and Hairy genes in nephrogenesis.

NOTCH1 JAG1 NOTCH3 NOTCH4

1.39e-091732415821257
Pubmed

Developmental coronary maturation is disturbed by aberrant cardiac vascular endothelial growth factor expression and Notch signalling.

NOTCH1 JAG1 NOTCH3 NOTCH4

1.79e-091832418093989
Pubmed

RBPjkappa-dependent Notch function regulates Gata2 and is essential for the formation of intra-embryonic hematopoietic cells.

NOTCH1 JAG1 NOTCH3 NOTCH4

1.79e-091832415689374
Pubmed

Notch 2 and Notch 1/3 segregate to neuronal and glial lineages of the developing olfactory epithelium.

NOTCH1 JAG1 NOTCH3 NOTCH4

2.26e-091932416518823
Pubmed

Prognostic roles of mRNA expression of notch receptors in non-small cell lung cancer.

NOTCH1 NOTCH3 NOTCH4

2.83e-09432328061457
Pubmed

The 4 Notch receptors play distinct and antagonistic roles in the proliferation and hepatocytic differentiation of liver progenitors.

NOTCH1 NOTCH3 NOTCH4

2.83e-09432324145721
Pubmed

A switch in Notch gene expression parallels stem cell to endothelial transition in infantile hemangioma.

NOTCH1 NOTCH3 NOTCH4

2.83e-09432320069356
Pubmed

Expression and clinical significance of Notch receptors in human renal cell carcinoma.

NOTCH1 NOTCH3 NOTCH4

2.83e-09432319404845
Pubmed

Notch signaling pathway regulates the growth and the expression of inflammatory cytokines in mouse basophils.

NOTCH1 NOTCH3 NOTCH4

2.83e-09432328669409
Pubmed

Mouse jagged1 physically interacts with notch2 and other notch receptors. Assessment by quantitative methods.

NOTCH1 JAG1 NOTCH3

2.83e-09432310551863
Pubmed

Evolutionary analysis of vertebrate Notch genes.

NOTCH1 NOTCH3 NOTCH4

2.83e-09432311466531
Pubmed

Abnormal expression pattern of Notch receptors, ligands, and downstream effectors in the dorsolateral prefrontal cortex and amygdala of suicidal victims.

NOTCH1 NOTCH3 NOTCH4

2.83e-09432324151014
Pubmed

Jagged1-mediated Notch activation induces epithelial-to-mesenchymal transition through Slug-induced repression of E-cadherin.

NOTCH1 JAG1 NOTCH4

2.83e-09432317984306
Pubmed

Activation of Notch signaling in human tongue carcinoma.

NOTCH1 JAG1 NOTCH3

2.83e-09432320819128
Pubmed

Characterization and developmental expression of the amphioxus homolog of Notch (AmphiNotch): evolutionary conservation of multiple expression domains in amphioxus and vertebrates.

NOTCH1 NOTCH3 NOTCH4

2.83e-09432311401408
Pubmed

Notch as a mediator of cell fate determination in hematopoiesis: evidence and speculation.

NOTCH1 NOTCH3 NOTCH4

2.83e-09432310194420
Pubmed

Functional conservation of mouse Notch receptor family members.

NOTCH1 NOTCH3 NOTCH4

2.83e-0943238898100
Pubmed

Notch1 and Notch4 core binding domain peptibodies exhibit distinct ligand-binding and anti-angiogenic properties.

NOTCH1 JAG1 NOTCH4

2.83e-09432336376768
Pubmed

Conservation of the biochemical mechanisms of signal transduction among mammalian Notch family members.

NOTCH1 NOTCH3 NOTCH4

2.83e-09432311459941
Pubmed

Mutational analysis of NOTCH1, 2, 3 and 4 genes in common solid cancers and acute leukemias.

NOTCH1 NOTCH3 NOTCH4

2.83e-09432318184405
Pubmed

Detection of Notch signaling molecules in cemento-ossifying fibroma of the jaws.

NOTCH1 JAG1 NOTCH3

2.83e-09432320040020
Pubmed

Notch signaling in the mammalian central nervous system: insights from mouse mutants.

NOTCH1 NOTCH3 NOTCH4

2.83e-09432315917835
Pubmed

Notch pathway activity identifies cells with cancer stem cell-like properties and correlates with worse survival in lung adenocarcinoma.

NOTCH1 NOTCH3 NOTCH4

2.83e-09432323444212
Pubmed

Deregulated expression of Notch receptors in human hepatocellular carcinoma.

NOTCH1 NOTCH3 NOTCH4

2.83e-09432317920003
Pubmed

Neurovascular EGFL7 regulates adult neurogenesis in the subventricular zone and thereby affects olfactory perception.

NOTCH1 JAG1 NOTCH3 NOTCH4

3.49e-092132428656980
Pubmed

Conversion of biliary system to pancreatic tissue in Hes1-deficient mice.

NOTCH1 JAG1 NOTCH3 NOTCH4

3.49e-092132414702043
Pubmed

Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation.

NOTCH1 JAG1 NOTCH3 NOTCH4

5.16e-092332414701881
Pubmed

Loss of function of the maternal membrane oestrogen receptor ERα alters expansion of trophoblast cells and impacts mouse fertility.

NOTCH1 JAG1 NOTCH3 NOTCH4

5.16e-092332436239412
Pubmed

Rbpj regulates development of prosensory cells in the mammalian inner ear.

NOTCH1 JAG1 NOTCH3 NOTCH4

6.19e-092432421420948
Pubmed

Physical interaction of Delta1, Jagged1, and Jagged2 with Notch1 and Notch3 receptors.

NOTCH1 JAG1 NOTCH3

7.07e-09532311006133
Pubmed

Notch and MAML-1 complexation do not detectably alter the DNA binding specificity of the transcription factor CSL.

NOTCH1 NOTCH3 NOTCH4

7.07e-09532321124806
Pubmed

Functional diversity of notch family genes in fetal lung development.

NOTCH1 JAG1 NOTCH3

7.07e-09532315064243
Pubmed

Intraovarian regulation of gonadotropin-dependent folliculogenesis depends on notch receptor signaling pathways not involving Delta-like ligand 4 (Dll4).

NOTCH1 NOTCH3 NOTCH4

7.07e-09532323675950
Pubmed

Notch-3 and Notch-4 signaling rescue from apoptosis human B-ALL cells in contact with human bone marrow-derived mesenchymal stromal cells.

JAG1 NOTCH3 NOTCH4

7.07e-09532321602525
Pubmed

MAML1, a human homologue of Drosophila mastermind, is a transcriptional co-activator for NOTCH receptors.

NOTCH1 NOTCH3 NOTCH4

7.07e-09532311101851
Pubmed

Association of Notch pathway down-regulation with Triple Negative/Basal-like breast carcinomas and high tumor-infiltrating FOXP3+ Tregs.

NOTCH1 JAG1 NOTCH4

7.07e-09532327118257
Pubmed

Hepatic Notch2 deficiency leads to bile duct agenesis perinatally and secondary bile duct formation after weaning.

NOTCH1 JAG1 NOTCH3 NOTCH4

8.70e-092632425446530
Pubmed

Notch signaling controls liver development by regulating biliary differentiation.

NOTCH1 JAG1 NOTCH3 NOTCH4

8.70e-092632419369401
Pubmed

Notch signaling prevents mucous metaplasia in mouse conducting airways during postnatal development.

NOTCH1 JAG1 NOTCH3 NOTCH4

1.02e-082732421791528
Pubmed

Cdc42-mediated tubulogenesis controls cell specification.

NOTCH1 JAG1 NOTCH3 NOTCH4

1.19e-082832419914171
Pubmed

Repression of Sox9 by Jag1 is continuously required to suppress the default chondrogenic fate of vascular smooth muscle cells.

NOTCH1 JAG1 NOTCH3 NOTCH4

1.38e-082932425535917
Pubmed

Notch signaling in stomach epithelial stem cell homeostasis.

NOTCH1 JAG1 NOTCH3 NOTCH4

1.38e-082932421402740
Pubmed

RBP-L, a transcription factor related to RBP-Jkappa.

NOTCH1 NOTCH3 NOTCH4

1.41e-0863239111338
Pubmed

Notch signaling is a critical regulator of allogeneic CD4+ T-cell responses mediating graft-versus-host disease.

NOTCH1 NOTCH3 NOTCH4

1.41e-08632320870902
Pubmed

Profiling immunohistochemical expression of NOTCH1-3, JAGGED1, cMET, and phospho-MAPK in 100 carcinomas of unknown primary.

NOTCH1 JAG1 NOTCH3

1.41e-08632322526456
Pubmed

Epidermal growth factor-like domain 7 (EGFL7) modulates Notch signalling and affects neural stem cell renewal.

NOTCH1 NOTCH3 NOTCH4

1.41e-08632319503073
Pubmed

Whn and mHa3 are components of the genetic hierarchy controlling hair follicle differentiation.

KRT31 KRT33A KRT33B

1.41e-08632310559501
Pubmed

Aberrant expression of Notch signaling molecules in patients with immune thrombocytopenic purpura.

NOTCH1 JAG1 NOTCH3

1.41e-08632319603167
Pubmed

Three genes in the human MHC class III region near the junction with the class II: gene for receptor of advanced glycosylation end products, PBX2 homeobox gene and a notch homolog, human counterpart of mouse mammary tumor gene int-3.

NOTCH1 NOTCH3 NOTCH4

1.41e-0863237835890
Pubmed

Interaction with factor inhibiting HIF-1 defines an additional mode of cross-coupling between the Notch and hypoxia signaling pathways.

NOTCH1 NOTCH3 NOTCH4

1.41e-08632318299578
Pubmed

Notch4 reveals a novel mechanism regulating Notch signal transduction.

NOTCH1 JAG1 NOTCH4

1.41e-08632324667410
Pubmed

Mouse Serrate-1 (Jagged-1): expression in the developing tooth is regulated by epithelial-mesenchymal interactions and fibroblast growth factor-4.

NOTCH1 JAG1 NOTCH3

1.41e-0863239108364
Pubmed

Cloning and functional characterization of the murine mastermind-like 1 (Maml1) gene.

NOTCH1 NOTCH3 NOTCH4

1.41e-08632315019995
Pubmed

Notch controls the magnitude of T helper cell responses by promoting cellular longevity.

NOTCH1 NOTCH3 NOTCH4

1.41e-08632322615412
Pubmed

Notch lineages and activity in intestinal stem cells determined by a new set of knock-in mice.

NOTCH1 NOTCH3 NOTCH4

1.41e-08632321991352
Pubmed

Notch signaling regulates ovarian follicle formation and coordinates follicular growth.

NOTCH1 JAG1 NOTCH3 NOTCH4

1.59e-083032424552588
Pubmed

ESCRT-dependent control of craniofacial morphogenesis with concomitant perturbation of NOTCH signaling.

NOTCH1 JAG1 NOTCH3 NOTCH4

1.82e-083132437573008
Pubmed

Expression pattern of notch1, 2 and 3 and Jagged1 and 2 in lymphoid and stromal thymus components: distinct ligand-receptor interactions in intrathymic T cell development.

NOTCH1 JAG1 NOTCH3

2.47e-08732310383933
Pubmed

Impaired expression of Notch signaling genes in aged human skeletal muscle.

NOTCH1 JAG1 NOTCH3

2.47e-08732317301032
Pubmed

Murine notch homologs (N1-4) undergo presenilin-dependent proteolysis.

NOTCH1 NOTCH3 NOTCH4

2.47e-08732311518718
Pubmed

Differentiation of CD11c+ CX3CR1+ cells in the small intestine requires Notch signaling.

NOTCH1 JAG1 NOTCH3

2.47e-08732324711412
Pubmed

Vascular patterning defects associated with expression of activated Notch4 in embryonic endothelium.

JAG1 NOTCH3 NOTCH4

2.47e-08732311344305
Pubmed

Sustained Notch signaling in progenitors is required for sequential emergence of distinct cell lineages during organogenesis.

NOTCH1 JAG1 NOTCH3 NOTCH4

2.68e-083432417015435
Pubmed

Differential Notch signaling in the epicardium is required for cardiac inflow development and coronary vessel morphogenesis.

NOTCH1 JAG1 NOTCH3 NOTCH4

2.68e-083432421311046
Pubmed

Notch signaling regulates smooth muscle differentiation of epicardium-derived cells.

NOTCH1 JAG1 NOTCH3 NOTCH4

3.03e-083532421252157
Pubmed

Notch signaling in postnatal pituitary expansion: proliferation, progenitors, and cell specification.

NOTCH1 JAG1 NOTCH3 NOTCH4

3.81e-083732424673559
Pubmed

P4 down-regulates Jagged2 and Notch1 expression during primordial folliculogenesis.

NOTCH1 JAG1 NOTCH3

3.95e-08832322652674
Pubmed

Expression of Hairy/Enhancer of Split genes, Hes1 and Hes5, during murine nephron morphogenesis.

NOTCH1 JAG1 NOTCH3

3.95e-08832315465493
Pubmed

Notch/Delta expression in the developing mouse lung.

NOTCH1 JAG1 NOTCH3

3.95e-08832311044610
Pubmed

Foxp1/4 control epithelial cell fate during lung development and regeneration through regulation of anterior gradient 2.

NOTCH1 JAG1 NOTCH3 NOTCH4

5.83e-084132422675208
InteractionNTN5 interactions

LRP2 FBLN5 NOTCH1 NOTCH3

5.44e-0824324int:NTN5
InteractionFBXO2 interactions

LRP2 SNED1 LAMC2 LAMC3 NOTCH1 JAG1 NOTCH3 CEMIP

1.92e-07411328int:FBXO2
InteractionHOXA1 interactions

RGS17 FBLN5 KRT31 KRT33B NOTCH1 NOTCH3 SLIT1

1.16e-06356327int:HOXA1
InteractionZFP41 interactions

LRP1 LRP2 FBLN5 NOTCH3

1.95e-0657324int:ZFP41
InteractionMAML2 interactions

NOTCH1 NOTCH3 NOTCH4

2.44e-0617323int:MAML2
InteractionMAML3 interactions

NOTCH1 NOTCH3 NOTCH4

4.07e-0620323int:MAML3
InteractionIGFL3 interactions

LRP2 FBLN5 NOTCH1 NOTCH3

5.88e-0675324int:IGFL3
InteractionEGFL7 interactions

FBLN5 NOTCH1 NOTCH3 NOTCH4

6.53e-0677324int:EGFL7
InteractionAPBB1 interactions

LRP1 LRP2 THBS3 NOTCH1 JAG1

1.31e-05195325int:APBB1
InteractionPC interactions

LRP1 THBS3 ADAM7 PHF21A CEMIP

1.38e-05197325int:PC
InteractionZNF74 interactions

FBLN5 NOTCH1 NOTCH3

2.10e-0534323int:ZNF74
InteractionDLK2 interactions

LRP2 NOTCH1 NOTCH3

2.51e-0536323int:DLK2
InteractionNOTCH3 interactions

NOTCH1 JAG1 NOTCH3 NOTCH4

2.99e-05113324int:NOTCH3
InteractionDLL4 interactions

NOTCH1 NOTCH4

3.65e-056322int:DLL4
InteractionJAG1 interactions

NOTCH1 JAG1 NOTCH3

3.72e-0541323int:JAG1
InteractionTHBS1 interactions

LRP1 LRP2 THBS3 JAG1

4.72e-05127324int:THBS1
InteractionTTLL5 interactions

THBS3 FBLN5 CEMIP

6.38e-0549323int:TTLL5
InteractionLPA interactions

LRP2 FBLN5

1.33e-0411322int:LPA
InteractionMAML1 interactions

NOTCH1 NOTCH3 NOTCH4

2.10e-0473323int:MAML1
InteractionATN1 interactions

LRP2 FBLN5 KRT31 SLIT1

2.11e-04187324int:ATN1
InteractionIGSF5 interactions

NOTCH1 NOTCH3

2.20e-0414322int:IGSF5
InteractionCUBN interactions

LRP1 LRP2

2.53e-0415322int:CUBN
InteractionMTO1 interactions

LRP1 THBS3 ADAM7

2.85e-0481323int:MTO1
InteractionSCN3A interactions

LRP1 LRP2

2.89e-0416322int:SCN3A
InteractionMKRN2 interactions

ELAVL2 NOTCH1 NOTCH3 SLIT1 CEMIP

3.26e-04385325int:MKRN2
InteractionPSEN2 interactions

NOTCH1 NOTCH3 NOTCH4

3.40e-0486323int:PSEN2
InteractionLTBP1 interactions

LAMA2 FBLN5 NOTCH3

4.15e-0492323int:LTBP1
InteractionZNF224 interactions

LRP2 NOTCH3

4.56e-0420322int:ZNF224
InteractionNOTCH4 interactions

NOTCH3 NOTCH4

5.03e-0421322int:NOTCH4
InteractionCASR interactions

NOTCH1 NOTCH3

5.53e-0422322int:CASR
InteractionDTX4 interactions

FAT1 NOTCH1

5.53e-0422322int:DTX4
InteractionDAB1 interactions

LRP1 LRP2 NOTCH1

6.45e-04107323int:DAB1
InteractionRBPJ interactions

NOTCH1 PHF21A NOTCH3 NOTCH4

6.71e-04254324int:RBPJ
InteractionJAG2 interactions

NOTCH1 JAG1 NOTCH3

6.99e-04110323int:JAG2
Cytoband17q12-q21

KRT31 KRT33A

2.30e-043232217q12-q21
CytobandEnsembl 112 genes in cytogenetic band chr17q21

DHX58 KRT31 KRT33A KRT33B

3.18e-04473324chr17q21
Cytoband17q21.2

DHX58 KRT33B

1.10e-037032217q21.2
GeneFamilyLaminin subunits

LAMA2 LAMC2 LAMC3

5.10e-0712253626
GeneFamilyKeratins, type I

KRT31 KRT33A KRT33B

7.48e-0628253608
GeneFamilyLow density lipoprotein receptors

LRP1 LRP2

1.42e-0413252634
GeneFamilyAnkyrin repeat domain containing

NOTCH1 NOTCH3 NOTCH4

4.38e-03242253403
GeneFamilyADAM metallopeptidase domain containing|CD molecules

LRP1 JAG1 ICAM4

1.66e-02394253471
CoexpressionNABA_ECM_GLYCOPROTEINS

LAMA2 SNED1 LAMC2 LAMC3 EYS THBS3 FBLN5 SLIT1

7.64e-11196328M3008
CoexpressionNABA_CORE_MATRISOME

LAMA2 SNED1 LAMC2 LAMC3 EYS THBS3 FBLN5 SLIT1

1.12e-09275328M5884
CoexpressionNABA_ECM_GLYCOPROTEINS

LAMA2 SNED1 LAMC2 LAMC3 THBS3 FBLN5 SLIT1

2.82e-09191327MM17059
CoexpressionFUKUSHIMA_TNFSF11_TARGETS

NOTCH1 JAG1 NOTCH3 NOTCH4

3.29e-0916324M2207
CoexpressionFUKUSHIMA_TNFSF11_TARGETS

NOTCH1 JAG1 NOTCH3 NOTCH4

3.29e-0916324MM1296
CoexpressionNABA_CORE_MATRISOME

LAMA2 SNED1 LAMC2 LAMC3 THBS3 FBLN5 SLIT1

3.08e-08270327MM17057
CoexpressionDELYS_THYROID_CANCER_DN

LRP2 LAMA2 RGS17 FBLN5 FCGBP ITPR1

3.46e-07233326M13273
CoexpressionGAO_LARGE_INTESTINE_ADULT_CJ_IMMUNE_CELLS

LRP1 SNED1 LAMC3 FBLN5 NOTCH3 NOTCH4 ITPR1

2.10e-06505327M39167
CoexpressionNABA_MATRISOME

LAMA2 SNED1 LAMC2 LAMC3 EYS THBS3 FBLN5 ADAM7 SLIT1

2.59e-061026329M5889
CoexpressionLEE_BMP2_TARGETS_UP

LRP1 LAMA2 HBP1 LAMC3 THBS3 FBLN5 JAG1 NOTCH3

3.31e-06780328M2324
CoexpressionLEE_BMP2_TARGETS_UP

LRP1 LAMA2 HBP1 LAMC3 THBS3 FBLN5 JAG1 NOTCH3

4.18e-06805328MM1067
CoexpressionFAN_EMBRYONIC_CTX_BIG_GROUPS_BRAIN_ENDOTHELIAL

LAMA2 LAMC3 NOTCH1 JAG1 NOTCH3 NOTCH4

4.67e-06365326M39018
CoexpressionCAMPS_COLON_CANCER_COPY_NUMBER_UP

KRT31 KRT33A KRT33B NOTCH1

4.95e-0693324M18750
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HRGL2A

LRP1 LRP2 KCNN3 FAT1 NOTCH1 JAG1 SLIT1

6.51e-06600327M39055
CoexpressionHALLMARK_NOTCH_SIGNALING

NOTCH1 JAG1 NOTCH3

8.00e-0632323M5903
CoexpressionLIU_CDX2_TARGETS_UP

JAG1 NOTCH3 NOTCH4

1.05e-0535323M16637
CoexpressionSNIJDERS_AMPLIFIED_IN_HEAD_AND_NECK_TUMORS

EYS PHF21A JAG1

1.25e-0537323M12802
CoexpressionMURARO_PANCREAS_MESENCHYMAL_STROMAL_CELL

LAMA2 LAMC3 FAT1 NOTCH1 JAG1 NOTCH3 CEMIP

1.48e-05681327M39175
CoexpressionJAEGER_METASTASIS_DN

LAMC2 FCGBP KRT31 KRT33A JAG1

1.49e-05260325M10702
CoexpressionNABA_BASEMENT_MEMBRANES

LAMA2 LAMC2 LAMC3

1.58e-0540323M5887
CoexpressionHALLMARK_WNT_BETA_CATENIN_SIGNALING

NOTCH1 JAG1 NOTCH4

1.84e-0542323M5895
CoexpressionNABA_MATRISOME

LAMA2 SNED1 LAMC2 LAMC3 THBS3 FBLN5 ADAM7 SLIT1

2.15e-051008328MM17056
CoexpressionBRUNEAU_HEART_GREAT_VESSELS_AND_VALVULOGENESIS

NOTCH1 JAG1

4.02e-058322M9884
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HRGL3

LRP1 LRP2 KCNN3 FAT1 FBLN5 SLIT1

6.00e-05574326M39056
CoexpressionGSE13522_CTRL_VS_T_CRUZI_BRAZIL_STRAIN_INF_SKIN_DN

LRP1 FAT1 DHX58 PHF21A

9.81e-05199324M2921
CoexpressionGSE3203_HEALTHY_VS_INFLUENZA_INFECTED_LN_BCELL_DN

SNED1 ELAVL2 NOTCH3 SLIT1

1.00e-04200324M6791
CoexpressionGSE17721_LPS_VS_CPG_1H_BMDC_DN

KCNN3 LAMC2 PHF21A ICAM4

1.00e-04200324M3987
CoexpressionGSE5589_LPS_AND_IL10_VS_LPS_AND_IL6_STIM_IL6_KO_MACROPHAGE_45MIN_DN

LRP1 HBP1 STAB2 ICAM4

1.00e-04200324M6626
CoexpressionHALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION

LRP1 LAMA2 LAMC2 FBLN5

1.00e-04200324M5930
CoexpressionHALLMARK_APICAL_JUNCTION

LAMC2 THBS3 KRT31 ICAM4

1.00e-04200324M5915
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HRGL2B

LRP1 LRP2 KCNN3 FAT1 NOTCH1

1.79e-04439325M39054
CoexpressionMEISSNER_BRAIN_HCP_WITH_H3K4ME3_AND_H3K27ME3

LRP2 SNED1 LAMC2 LAMC3 NOTCH1 JAG1 CEMIP

2.60e-041074327M1941
CoexpressionTANAKA_METHYLATED_IN_ESOPHAGEAL_CARCINOMA

KRT31 KRT33A KRT33B

2.61e-04102323M14455
CoexpressionNABA_MATRISOME_BLEO_FIBROTIC_LUNG

LAMC2 FBLN5

2.71e-0420322MM17053
CoexpressionBROWNE_HCMV_INFECTION_48HR_DN

LAMA2 SNED1 LAMC2 THBS3 FBLN5

2.75e-04482325M12144
CoexpressionBOQUEST_STEM_CELL_UP

LRP1 LAMA2 FAT1 FBLN5

2.77e-04261324M1834
CoexpressionSHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM5

LRP2 LAMC2 JAG1

3.09e-04108323M1281
CoexpressionHEBERT_MATRISOME_TNBC_LUNG_METASTASIS

LAMC2 FBLN5

3.60e-0423322M48001
CoexpressionHE_LIM_SUN_FETAL_LUNG_C3_ARTERIAL_ENDOTHELIAL_CELL

KCNN3 FBLN5 JAG1 ITPR1

3.92e-04286324M45746
CoexpressionSHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM5

LRP2 LAMC2 JAG1

4.01e-04118323MM536
CoexpressionNABA_MATRISOME_POORLY_METASTATIC_BREAST_CANCER

LAMA2 FBLN5

4.26e-0425322M47986
CoexpressionKORKOLA_EMBRYONIC_CARCINOMA_VS_SEMINOMA_DN

ELAVL2 FBLN5

4.26e-0425322M15380
CoexpressionLU_TUMOR_ANGIOGENESIS_UP

NOTCH1 JAG1

4.26e-0425322M9946
CoexpressionCHEN_ETV5_TARGETS_SERTOLI

ELAVL2 CEMIP

4.26e-0425322M1586
CoexpressionFAN_EMBRYONIC_CTX_BRAIN_ENDOTHELIAL_2

LAMA2 LAMC3 NOTCH3 ITPR1

4.88e-04303324M39040
CoexpressionSHIN_B_CELL_LYMPHOMA_CLUSTER_7

NOTCH3 NOTCH4

4.97e-0427322M1391
CoexpressionSHIN_B_CELL_LYMPHOMA_CLUSTER_7

NOTCH3 NOTCH4

4.97e-0427322MM1135
CoexpressionCHEN_ETV5_TARGETS_SERTOLI

ELAVL2 CEMIP

5.74e-0429322MM675
CoexpressionGSE9946_MATURE_STIMULATORY_VS_PROSTAGLANDINE2_TREATED_MATURE_DC_DN

FAT1 FBLN5 JAG1

6.20e-04137323M429
CoexpressionPECE_MAMMARY_STEM_CELL_DN

SNED1 RGS17 JAG1

7.17e-04144323M2535
CoexpressionHE_LIM_SUN_FETAL_LUNG_C3_OMD_POS_ENDOTHELIAL_CELL

THBS3 FBLN5 JAG1 ITPR1

8.82e-04355324M45758
CoexpressionMARTINEZ_RB1_TARGETS_DN

LAMA2 KRT31 KRT33A KRT33B NOTCH1

9.29e-04630325MM1038
CoexpressionMURARO_PANCREAS_ENDOTHELIAL_CELL

KCNN3 NOTCH1 JAG1 NOTCH4

9.48e-04362324M39176
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HRGL1

KCNN3 FAT1 NOTCH1 SLIT1

9.67e-04364324M39057
CoexpressionVART_KSHV_INFECTION_ANGIOGENIC_MARKERS_UP

STAB2 JAG1 NOTCH4

1.03e-03163323M12112
CoexpressionAtlasfacebase_RNAseq_e14.5_palate_poster_distal_ERK2_WT_2500_K1

LAMA2 SNED1 HBP1 RGS17 FAT1 THBS3 FBLN5 PHF21A SLIT1

3.91e-051166329facebase_RNAseq_e14.5_palate_poster_distal_ERK2_WT_2500_K1
CoexpressionAtlasStromal Cells, St.31-38-44-.SLN, CD45- gp38- CD31- CD44-, Lymph Node, avg-2

LRP1 LAMA2 FAT1 FBLN5 JAG1 NOTCH3

5.16e-05453326GSM777067_500
CoexpressionAtlasStromal Cells, FRC.SLN, gp38+ CD31- CD140a+, Lymph Node, avg-4

LRP1 SNED1 FAT1 FBLN5 JAG1 NOTCH3

5.29e-05455326GSM777055_500
CoexpressionAtlasFacebaseRNAseq_e10.5_Olfactory Pit_top-relative-expression-ranked_2500_k-means-cluster#1

LRP2 KCNN3 ELAVL2 RGS17 FAT1

7.41e-05295325Facebase_RNAseq_e10.5_Olfactory Pit_2500_K1
CoexpressionAtlaskidney_P4_CapMesRenVes_Crym_k-means-cluster#3_top-relative-expression-ranked_200

LAMC2 NOTCH1 JAG1

1.11e-0462323gudmap_kidney_P4_CapMesRenVes_Crym_k3_200
ToppCellCOVID-19-Heart-Fib_+_EC_+_Pericyte|Heart / Disease (COVID-19 only), tissue and cell type

LRP1 LAMA2 SNED1 FBLN5 ITPR1

2.46e-0719232560b1312e84f6d6448365a952469c506c00b5fe93
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 LAMA2 RGS17 THBS3 FBLN5

2.46e-071923255e6f8206ee0b10cdba79a7c4a05452cb025a5512
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal-fibroblast|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 LAMA2 RGS17 THBS3 FBLN5

2.46e-07192325136af0186c70c14c5f2b33ed7a148156de5b478c
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 LAMA2 LAMC3 FBLN5 CEMIP

2.53e-07193325dc8e62df6121ee99b156aca6b1b3ae555739b6f2
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 LAMA2 LAMC3 FBLN5 CEMIP

2.53e-07193325e2ee077fd381bd906e6b4329f22e7d106e422a7f
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 LAMA2 LAMC3 FBLN5 NOTCH3

2.66e-07195325edd4cd8402af81737b2074f9dce71cc6ab09be7e
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 LAMA2 SNED1 LAMC3 FBLN5

2.66e-07195325d9a5c75d31c6e8bb1e1ab7fd115ac5deb5fb1c8d
ToppCellfacs-Thymus-Thymus_Epithelium|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 LRP2 LAMA2 FAT1 JAG1

2.73e-071963256bc1187dfc4860a4e09032d7ea87ba3d9fe9f363
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 LAMA2 SNED1 LAMC3 FBLN5

2.73e-07196325a12dd986df65c36f248cf10815c3b8b6238613b0
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 LAMA2 LAMC3 FBLN5 NOTCH3

2.73e-07196325802f61e78a9a1030a86c4a980c398a73cd4d1574
ToppCellfacs-Thymus-Thymus_Epithelium-18m|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 LRP2 LAMA2 FAT1 JAG1

2.73e-07196325c8c89e469402e11aa2a9561e859b6fd1fb66c39b
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 LAMA2 SNED1 LAMC3 FBLN5

2.73e-071963253e6803587d8566fd08cb8b290be3b6461743d79c
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 LAMA2 LAMC3 FBLN5 NOTCH3

2.73e-07196325fa445f4240c521cf04eb2e2f79a5c55fda31209a
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 LAMA2 SNED1 LAMC3 FBLN5

2.80e-07197325b349f8e96d61a4c296af64711e11fc44459a9413
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 LAMA2 LAMC3 FBLN5 CEMIP

2.80e-071973254cf4e9553397cd8dee883dbec24f41bec41aff99
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 LAMA2 SNED1 LAMC3 FBLN5

2.80e-071973256d027119a5f7ca2aac1b10837e43f9a2bb54db85
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 LAMA2 LAMC3 FBLN5 CEMIP

2.80e-07197325ae0435f4b4a9cdedb1c201fc56921048390097bf
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 LAMA2 LAMC3 FBLN5 CEMIP

2.80e-0719732537f6b6f2809b952382eaebb642b0aad6371f4251
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 LAMA2 SNED1 LAMC3 FBLN5

2.80e-07197325c2e390653d5dee7e731c1840cfdab41987dede9b
ToppCellCOVID-19-lung-Fibroblast|COVID-19 / Disease (COVID-19 only), tissue and cell type

LRP1 LAMA2 SNED1 FBLN5 CEMIP

2.87e-071983253ec01a55ade5e1627258cc3cfebb2c3207a4cb43
ToppCellLPS_only-Mesenchymal_myocytic-Pericyte|LPS_only / Treatment groups by lineage, cell group, cell type

LAMA2 LAMC3 FAT1 JAG1 NOTCH3

3.02e-072003258c8ef2b19ab5b1bfc0fae6c38a330f464f28e86f
ToppCellControl_saline-Mesenchymal_myocytic-Pericyte|Control_saline / Treatment groups by lineage, cell group, cell type

LRP1 LAMA2 LAMC3 FAT1 NOTCH3

3.02e-07200325cb7ef774b6d300f8019c5b16a04e3ebd165e4f1c
ToppCell(5)_Fibroblast-E|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

LRP1 LAMA2 THBS3 FBLN5 SLIT1

3.02e-0720032575e5ecb05e965e24d569aa2ef5cdf740b1528c06
ToppCellControl_saline-Mesenchymal_myocytic-Pericyte-Pericyte_2|Control_saline / Treatment groups by lineage, cell group, cell type

LRP1 LAMA2 LAMC3 FAT1 NOTCH3

3.02e-07200325bc8949eb34482aca166c4602ff6ab876cb4c2c3c
ToppCellLPS_only-Unknown|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ELAVL2 LAMC3 ADAM7 NOTCH3

1.38e-061153247a733f6987b40ec497a03734b79ed5355ad3a2fc
ToppCellLPS_only-Unknown-Endothelial-Pericyte_2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ELAVL2 LAMC3 ADAM7 NOTCH3

1.38e-06115324c67145d3cd9243994a141749b426ff2a6dcc8d93
ToppCellLPS_only-Unknown-Endothelial|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ELAVL2 LAMC3 ADAM7 NOTCH3

1.38e-06115324ad5298c2ad8bf94fa13c2e50b0799e929473ef59
ToppCellCOVID-19-kidney-Mito-rich_Int|kidney / Disease (COVID-19 only), tissue and cell type

LAMA2 LAMC3 EYS KRT33B

2.18e-0612932457b705106aec7bbfc587de1ccd4f2335fc44dd6f
ToppCellLPS-antiTNF-Stromal_mesenchymal-Myocytic|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LAMA2 LAMC3 FAT1 NOTCH3

4.64e-061563246365b69ede98bc866e996bc52736b00401aacf6f
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_artery-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

KCNN3 FBLN5 JAG1 NOTCH4

5.38e-0616232425bb1b9709f960fdf90faff56e874f52a8f5d17e
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 LAMA2 THBS3 FBLN5

6.36e-061693248bfa2d3bb541d02f55d7c95b8fd156c8403befca
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Mesenchymal|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 LAMA2 THBS3 FBLN5

6.36e-06169324bb43abad2c049b7f4d307737347290e01b3339a3
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 LAMA2 THBS3 FBLN5

6.36e-061693245f18e3f40a5b1b167903f37516ec8181e889c7c5
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

LAMA2 SNED1 LAMC3 FBLN5

6.67e-06171324972fab891135bd755d5526cbc5a963200067b0a6
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

LAMA2 SNED1 LAMC3 FBLN5

6.67e-061713242a77ed79c6f2e700e789c80451a70ecb31639719
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LAMA2 SNED1 LAMC3 FBLN5

6.82e-061723241ef243bce63d841c25e4b74d029d1377f84bcc3d
ToppCellNasal_Brush-Epithelial-Basal_1|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

KCNN3 NOTCH4 ICAM4 CEMIP

6.82e-061723244483073469001770015526303772fd54906c5d68
ToppCellNasal_Brush-Epithelial-Basal_1|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

KCNN3 NOTCH4 ICAM4 CEMIP

6.82e-0617232458eaadf12366701103a0d1f133462c9495fedc30
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LAMA2 SNED1 LAMC3 FBLN5

6.82e-06172324ab1c81be29f93ca8920c6ab5ab92f497a9256d3f
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 LAMA2 LAMC3 FBLN5

7.47e-061763249bc87cd5cda2372e1bce94c9dfd408eb1dfd8d0c
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 LAMA2 LAMC3 FBLN5

7.47e-061763243f8274a7ab67f9f8a8923193763a5543cfe4defa
ToppCellP28-Endothelial-lymphatic_endothelial_cell-endothelial_cell_of_lymphatic_vessel|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

KCNN3 SNED1 FBLN5 STAB2

7.64e-06177324e96a7e4544710aaab8bd2800ecff9667880a8bf4
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_artery|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

KCNN3 FBLN5 JAG1 NOTCH4

7.64e-061773245ff8dcfb030312126695d53a026d2e104a401b83
ToppCellP28-Endothelial-lymphatic_endothelial_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

KCNN3 SNED1 FBLN5 STAB2

7.64e-061773246e330aa3c87fd640526b746a9deb3b2250d2518c
ToppCellE12.5-Mesenchymal-myocytic_cell-vascular_associated_smooth_muscle_cell|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

FBLN5 NOTCH1 JAG1 NOTCH3

7.64e-061773245cdf413f82376a95467322b16d10b0d1e7557e2d
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FBLN5 NOTCH1 JAG1 NOTCH4

8.34e-061813244d7793026373cbcf04b15c77f95f1025d07d4c00
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 LAMA2 LAMC3 FBLN5

8.34e-06181324c62b0a2422377ffadaab63edd538e87a06fa5017
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 LAMA2 LAMC3 FBLN5

8.34e-06181324c6d2a13df3b74fade3b0c71e285b4c14c8e52413
ToppCell5'-GW_trimst-2-SmallIntestine-Endothelial-blood_vessel_EC-Mature_arterial_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

EYS FBLN5 JAG1 ITPR1

8.34e-061813240ba91575fe8851788cebc4cf5a6d76680bf586c5
ToppCellfacs-Lung-24m-Endothelial-lymphatic_endothelial|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KCNN3 SNED1 FBLN5 STAB2

8.53e-061823240cde2775bdaaa2172499925bd59b0ac2d545eb27
ToppCellfacs-Lung-24m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KCNN3 SNED1 FBLN5 STAB2

8.53e-061823242cc434e46985c66fc36de05344a67aa96d90abc9
ToppCellfacs-Lung-24m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KCNN3 SNED1 FBLN5 STAB2

8.53e-061823243e7457b2a70b45735fb75d6617b7f34cef28758e
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FBLN5 NOTCH1 JAG1 NOTCH4

8.71e-061833243427f3cbe6ea81709750e7dd3ff378f03ae65eab
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

LAMA2 LAMC3 JAG1 NOTCH3

8.71e-06183324667717366cb181b8a04a347e64f0f5a4dfc6ee7f
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LAMA2 LAMC3 FAT1 NOTCH3

8.90e-06184324102b6f621a5b551e622f97b12d787c080b052a72
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LAMA2 LAMC3 FAT1 NOTCH3

8.90e-06184324689a8af81a79a4bb3123cfa01958c953eab5de98
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LAMA2 LAMC3 FAT1 NOTCH3

8.90e-06184324327ff3ac8d2fecdd5d242bdc34f0dfdb1c59a68b
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-Pecam____Kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMC3 FBLN5 JAG1 NOTCH4

9.09e-06185324f98af3146ec2f44c30d31a662fb9c4fa3ca4f706
ToppCellCOVID-19-Heart-Fib_2|COVID-19 / Disease (COVID-19 only), tissue and cell type

LRP1 LAMA2 SNED1 FBLN5

9.09e-061853248f95d8e591bf7379d13f5a0545b0cb49e2b1ab5d
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAT1 JAG1 NOTCH3 ITPR1

9.29e-061863244780af76237d7af2abbe2d8d5530cdf53e3ed0b7
ToppCellhuman_hepatoblastoma-Hepatic_Stellate_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

LAMA2 JAG1 NOTCH3 ITPR1

9.29e-06186324cb1fc4b9140666b43415e21c9b434dc9b144e9d0
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LAMA2 LAMC3 FAT1 NOTCH3

9.29e-06186324888e85a025bd982d36c910db0f5a3385b1ca3b28
ToppCellP03-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_artery|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

FBLN5 NOTCH1 JAG1 NOTCH4

9.49e-0618732466ebe1788d51b3e17bec6cdb219f709756b4e530
ToppCellwk_15-18-Endothelial-Blood_vessel_endothelial-GRIA2+_arterial_endo|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

EYS NOTCH1 JAG1 NOTCH4

9.69e-06188324366a2d59b9c81d8a7659749f9c07efa46b49a39a
ToppCellP07-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_artery|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

FBLN5 NOTCH1 JAG1 NOTCH4

9.69e-061883245bc1537e079c7435196c163bff5f639ea392a33a
ToppCelldroplet-Kidney-nan-3m-Epithelial-Pecam____Kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBLN5 JAG1 NOTCH3 NOTCH4

9.69e-06188324ec0e241de2c8310b4417b9d4e2420d7a1662f1c0
ToppCellCOVID-19-Heart-Fib_1|COVID-19 / Disease (COVID-19 only), tissue and cell type

LRP1 LAMA2 SNED1 FBLN5

9.69e-06188324fe361215f4ba841aa5e1e581fb56f2f4d3ccd201
ToppCelldroplet-Kidney-KIDNEY-30m-Mesenchymal-nan|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 LAMA2 THBS3 FBLN5

9.89e-06189324544d95df910f1b276995624509a7e41b219baca0
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LAMA2 LAMC3 FBLN5 CEMIP

9.89e-0618932471397e993a77d70b2eeede240bdfc7660b558987
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LAMA2 LAMC3 FBLN5 CEMIP

9.89e-061893244eea4759520c312bd17a681034d8074e47093d2b
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LRP1 LAMA2 SNED1 FBLN5

9.89e-06189324d531399749409d614adca13d181830c6e3287508
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 LAMC3 FBLN5 ITPR1

9.89e-06189324c734e5693808a0333139e87bd5be2597a9252afe
ToppCellPND01-Endothelial-Endothelial_blood-vessel-Macrovascular_EC|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FBLN5 NOTCH1 JAG1 NOTCH4

9.89e-061893241e1afa66b32ae752c0a42b02b80f10205464569c
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FBLN5 NOTCH1 JAG1 NOTCH4

9.89e-061893249da012fdfa9a8d488cab710a463a1d70e89f990c
ToppCelldroplet-Mammary_Gland-nan-21m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 LAMA2 THBS3 FBLN5

9.89e-06189324bc54ffd7bd1627a36747a80ce5139e4a69928400
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KCNN3 FBLN5 JAG1 NOTCH4

1.01e-05190324bf9bc57a605c7e3979bc4f7260e6fb92c3eb8690
ToppCellLV-01._Fibroblast_I|World / Chamber and Cluster_Paper

LAMA2 SNED1 LAMC2 FBLN5

1.01e-0519032412992ec80a7b4f4f17de693f0719ee061a9918fd
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 LAMA2 LAMC3 FBLN5

1.01e-051903241f83f7f24288a3b9ab33c2e113e845dba96adc8a
ToppCelldroplet-Mammary_Gland-nan-21m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 LAMA2 THBS3 FBLN5

1.01e-05190324f3ca94a31a35eed5fecf3c4b8c957e1bc4150158
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FBLN5 NOTCH1 JAG1 NOTCH4

1.01e-05190324d87b9e9ca863270a9c7f61674271a6440c97d1f4
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 LAMA2 LAMC3 FBLN5

1.01e-051903242306aa9dbeaef3be8484a5b236605de23cd75d4c
ToppCellPND01-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FBLN5 NOTCH1 JAG1 NOTCH4

1.01e-051903243346bfd0474828b3729cffa9f4cc57b04dd30443
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 LAMC3 FBLN5 ITPR1

1.01e-05190324445952b70abffadb6ccc1ed4bbf61a88b06b73b3
ToppCellLPS-IL1RA-Endothelial-Endothelial-Artery|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KCNN3 FBLN5 JAG1 NOTCH4

1.01e-05190324aed65d584ca0c25f6a8313c66b421a6618af82ea
ToppCelldroplet-Limb_Muscle-nan-24m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 LAMA2 THBS3 FBLN5

1.01e-05190324ad0f5605db6b694445ec9bd5dc8d2d834358c0f9
ToppCelldroplet-Mammary_Gland-nan-21m-Mesenchymal|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 LAMA2 THBS3 FBLN5

1.01e-05190324c2cd1eb674162ee40502c3380b7245c85079c7ce
ToppCellCOVID-19-kidney-AQP1+SLC14A1+EC|kidney / Disease (COVID-19 only), tissue and cell type

KCNN3 FBLN5 JAG1 NOTCH4

1.01e-051903241519f34d31fe0817184c5865a0bc9f0cb479b1a4
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 LAMC3 FBLN5 ITPR1

1.01e-051903242e592323085ba9c019d678ac2a784462ab470ed9
ToppCellPND01-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FBLN5 NOTCH1 JAG1 NOTCH4

1.01e-05190324eae5bcdb8a35f3fba4d25854c1a43f83f80832a2
ToppCelldroplet-Mammary_Gland-nan-18m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 LAMA2 THBS3 FBLN5

1.01e-0519032447077579496c5340e99f61499427a3a36b566da3
ToppCelldroplet-Heart-nan-24m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 LAMA2 RGS17 FBLN5

1.03e-051913241f660ea2841324d13f63e01f1789e606c2843fc4
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 LAMA2 LAMC3 FBLN5

1.03e-0519132439092a0aff8097617820c59f5fea9ee2bb4f63a2
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 LAMA2 LAMC3 FBLN5

1.03e-05191324a58c75e9580139fb370b498d95660f10f3a2a27b
ToppCelldroplet-Mammary_Gland-nan-18m-Mesenchymal|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 LAMA2 THBS3 FBLN5

1.03e-0519132419c67a812b8ce97472d316acd15aeefe8736000d
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 LAMC3 FBLN5 ITPR1

1.03e-05191324cb0aee740b08f7d5fdd2717ecf7429043b277ae7
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 LAMA2 RGS17 NOTCH3

1.03e-051913241efb47743b6834b64cb0f61721ddbe875b1a66ca
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 LAMA2 LAMC3 FBLN5

1.03e-05191324107113b930d9ad171f1b2aa20df4567c94fae7d8
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 LAMA2 SNED1 FBLN5

1.03e-05191324a6c57627077fa980b7ec1d3894b5f31bfb11b738
ToppCellfacs-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LRP1 LAMA2 THBS3 FBLN5

1.03e-051913242b73fcd592d16cae8ded5e45c8fbf2d9adc8caad
ToppCellRV-01._Fibroblast_I|World / Chamber and Cluster_Paper

LAMA2 SNED1 EYS FBLN5

1.03e-0519132470c067c54084bfb02c29bab085f4defd477194fb
DrugAC1L1G72

LAMA2 LAMC2 LAMC3

4.13e-0711323CID000003553
DrugAC1L1I0J

KRT31 KRT33A KRT33B

2.41e-0619323CID000004371
DrugLMWH

LRP1 LRP2 LAMA2 ELAVL2 LAMC2 LAMC3 THBS3 ITPR1

2.81e-06663328CID000000772
DrugEnoxacin [74011-58-8]; Down 200; 12.4uM; PC3; HT_HG-U133A

LRP1 LAMC3 STAB2 JAG1 NOTCH3

7.49e-061963254655_DN
DrugFinasteride [98319-26-7]; Up 200; 10.8uM; PC3; HT_HG-U133A

LRP1 LAMA2 RGS17 STAB2 CEMIP

7.68e-061973253744_UP
DrugPrednisone [53-03-2]; Up 200; 11.2uM; MCF7; HT_HG-U133A

LAMA2 ELAVL2 LAMC2 STAB2 ITPR1

8.06e-061993254400_UP
Drugbutyrate

LAMA2 LAMC2 HBP1 LAMC3 KRT31 KRT33A KRT33B PHF21A

8.20e-06767328CID000000264
DrugAC1L1B58

LAMA2 LAMC2 LAMC3

8.99e-0629323CID000001288
Drug1-anilino-4-methyl-2-methylthio-4-phenylimidazolin-5-one

LRP2 ELAVL2 FAT1 NOTCH1 NOTCH3 CEMIP

1.17e-05373326ctd:C540355
DrugVistar

KRT31 KRT33A KRT33B

1.74e-0536323CID000040896
DrugCalcort

LAMA2 LAMC2 LAMC3

2.06e-0538323CID000026709
Drugsulfur mustard

LAMC2 KRT31 KRT33A KRT33B

3.22e-05130324CID000010461
Drug9-(5',5'-difluoro-5'-phosphonopentyl)guanine

KRT31 KRT33A KRT33B

3.67e-0546323CID000448999
Drugabrine

LRP2 HBP1 STAB2 FCGBP DHX58

4.53e-05285325ctd:C496492
DrugNSC34533

KRT31 KRT33A KRT33B

5.96e-0554323CID000003512
Drugkalinin

LAMA2 LAMC2 LAMC3

6.30e-0555323CID000032518
Drugcoprogen

LRP1 LRP2

6.85e-059322CID006323272
DrugCC270

LAMA2 LAMC2 LAMC3

7.77e-0559323CID006918852
DrugLG 5

LAMA2 LAMC2 LAMC3

8.17e-0560323CID011840957
Drug2,2'-biphenol

HBP1 ICAM4

8.55e-0510322CID000015731
Drug25-azacoprostane

LRP1 LRP2

8.55e-0510322CID000162243
Drug2'-deoxythymidylyl-(3'-5')-2'-deoxyadenosine

NOTCH1 JAG1

8.55e-0510322ctd:C028145
DrugZuclopenthixol hydrochloride [633-59-0]; Up 200; 9.2uM; MCF7; HT_HG-U133A

LRP2 THBS3 ITPR1 CEMIP

1.14e-041803247356_UP
DrugFenoterol hydrobromide [1944-12-3]; Up 200; 10.4uM; PC3; HT_HG-U133A

LRP2 LAMC2 ITPR1 CEMIP

1.19e-041823246331_UP
DrugKorean red ginseng

KRT31 JAG1

1.25e-0412322CID000420552
DrugMonensin sodium salt [22373-78-0]; Down 200; 5.8uM; PC3; HT_HG-U133A

ELAVL2 LAMC2 NOTCH1 NOTCH3

1.32e-041873247402_DN
DrugPhenacetin [62-44-2]; Up 200; 22.4uM; MCF7; HT_HG-U133A

LRP2 STAB2 JAG1 ITPR1

1.38e-041893242832_UP
DrugProtriptyline hydrochloride [1225-55-4]; Up 200; 13.4uM; MCF7; HT_HG-U133A

SNED1 LAMC2 THBS3 CEMIP

1.44e-041913246498_UP
DrugDimethisoquin hydrochloride [2773-92-4]; Up 200; 13uM; MCF7; HT_HG-U133A

LRP1 SNED1 THBS3 ITPR1

1.44e-041913244791_UP
DrugTestosterone propionate [57-85-2]; Up 200; 11.6uM; PC3; HT_HG-U133A

LRP2 LAMA2 THBS3 JAG1

1.49e-041933244676_UP
DrugHydroxyzine dihydrochloride [2192-20-3]; Down 200; 9uM; PC3; HT_HG-U133A

LRP1 LAMC2 THBS3 NOTCH3

1.52e-041943246660_DN
DrugOxethazaine [126-27-2]; Up 200; 8.6uM; MCF7; HT_HG-U133A

ADAM7 JAG1 ITPR1 CEMIP

1.52e-041943244829_UP
Drugdysprosium

LAMA2 LAMC2 LAMC3

1.53e-0474323CID000023912
DrugButylparaben [94-26-8]; Up 200; 20.6uM; MCF7; HT_HG-U133A

LAMC2 ADAM7 NOTCH3 ITPR1

1.55e-041953245608_UP
DrugGibberellic acid [77-06-5]; Down 200; 11.6uM; PC3; HT_HG-U133A

LRP1 LAMC2 THBS3 JAG1

1.55e-041953244234_DN
DrugDehydroisoandosterone 3-acetate [853-23-6]; Down 200; 12.2uM; PC3; HT_HG-U133A

LRP1 LAMC2 LAMC3 THBS3

1.59e-041963246673_DN
DrugProtriptyline hydrochloride [1225-55-4]; Up 200; 13.4uM; PC3; HT_HG-U133A

LRP2 SNED1 LAMC2 STAB2

1.59e-041963246338_UP
Drugnovobiocin sodium, USP; Down 200; 100uM; PC3; HG-U133A

LRP1 ELAVL2 RGS17 STAB2

1.62e-04197324435_DN
DrugBeclomethasone dipropionate [5534-09-8]; Up 200; 7.6uM; MCF7; HT_HG-U133A

LAMA2 LAMC2 STAB2 ICAM4

1.62e-041973244403_UP
DrugHydroxyzine dihydrochloride [2192-20-3]; Up 200; 9uM; MCF7; HT_HG-U133A

LRP2 LAMC2 LAMC3 STAB2

1.65e-041983245006_UP
DrugEtofylline [519-37-9]; Up 200; 17.8uM; MCF7; HT_HG-U133A

LRP2 LAMC3 STAB2 ITPR1

1.65e-041983242256_UP
DrugCaptopril [62571-86-2]; Up 200; 17.2uM; MCF7; HT_HG-U133A

ELAVL2 LAMC2 STAB2 CEMIP

1.65e-041983244410_UP
DrugIsradipine [75695-93-1]; Up 200; 10.8uM; PC3; HT_HG-U133A

LRP2 LAMC2 STAB2 ITPR1

1.65e-041983246347_UP
DrugTetramisole hydrochloride [16595-80-5]; Up 200; 16.6uM; MCF7; HT_HG-U133A

SNED1 STAB2 ICAM4 ITPR1

1.65e-041983244412_UP
DrugClofilium tosylate [92953-10-1]; Up 200; 7.8uM; PC3; HT_HG-U133A

LRP2 LAMA2 LAMC3 ITPR1

1.65e-041983244492_UP
DrugThioperamide maleate [106243-16-7]; Up 200; 9.8uM; MCF7; HT_HG-U133A

LAMC2 HBP1 ITPR1 CEMIP

1.65e-041983245635_UP
DrugEthamsylate [2624-44-4]; Up 200; 15.2uM; MCF7; HT_HG-U133A

SNED1 LAMC2 HBP1 ITPR1

1.68e-041993244399_UP
DrugOrnidazole [16773-42-5]; Up 200; 18.2uM; PC3; HT_HG-U133A

LRP1 ELAVL2 JAG1 ITPR1

1.68e-041993242109_UP
DrugRibavirin [36791-04-5]; Up 200; 16.4uM; MCF7; HT_HG-U133A

LAMA2 SNED1 ADAM7 CEMIP

1.68e-041993246521_UP
DrugCanavanine sulfate monohydrate (L,+) [206996-57-8]; Up 200; 13.6uM; PC3; HT_HG-U133A

LRP2 LAMA2 ADAM7 ICAM4

1.68e-041993244197_UP
DrugSpectinomycin dihydrochloride [21736-83-4]; Up 200; 9.8uM; HL60; HT_HG-U133A

LRP1 LRP2 SNED1 ADAM7

1.71e-042003242987_UP
DrugGBR 12909 dihydrochloride [67469-78-7]; Down 200; 7.6uM; MCF7; HT_HG-U133A

LRP2 THBS3 STAB2 CEMIP

1.71e-042003243240_DN
DrugPHA-00745360 [351320-33-7]; Down 200; 1uM; PC3; HT_HG-U133A

LRP1 LRP2 LAMA2 LAMC3

1.71e-042003243827_DN
Drug2-amino-5-methylpyridine

LAMA2 LAMC2 LAMC3

1.72e-0477323CID000015348
DrugYIGSR

LAMA2 LAMC2 LAMC3

1.85e-0479323CID000123977
Drug2-[(1R,2R,3S,4R,5R,6S)-2-[(2R,5S)-3-[(3S,4S,5R,6S)-4,5-dihydroxy-3-(methylamino)-6-methylol-tetrahydropyran-2-yl]-4-formyl-4-hydroxy-5-methylol-tetrahydrofuran-2-yl]oxy-5-guanidino-3,4,6-trihydroxy-cyclohexyl]guanidine

LAMA2 LAMC2 LAMC3

2.15e-0483323CID011968896
Druglead stearate

JAG1 NOTCH3 NOTCH4

2.22e-0484323CID000061258
Drugalpha-chaconine

JAG1 ICAM4

2.27e-0416322CID000104750
DrugNSC 714187

LAMA2 LAMC2 LAMC3

2.30e-0485323CID005288693
Drug1,2-dimethylhydrazine

LAMA2 LAMC2 LAMC3

2.38e-0486323CID000001322
Drugazoxystrobin

JAG1 NOTCH3 ICAM4

2.55e-0488323CID003034285
Drugethylnylestradiol

LRP1 LRP2 KCNN3 FBLN5 KRT31 KRT33A KRT33B PHF21A

2.61e-041251328CID000003285
DrugH-9 dihydrochloride

LAMA2 LAMC2 LAMC3

2.73e-0490323CID000003544
Drugchlorobiphenyl

KCNN3 ICAM4

3.22e-0419322CID000249266
Drugquinocetone

LRP1 LAMA2 LAMC3 FBLN5

3.89e-04248324ctd:C502851
DiseaseCarcinoma, Pancreatic Ductal

NOTCH1 JAG1 NOTCH3 NOTCH4

1.19e-0824324C0887833
DiseaseGlioblastoma

FAT1 NOTCH1 JAG1 NOTCH3

1.62e-0679324C0017636
DiseaseGiant Cell Glioblastoma

FAT1 NOTCH1 JAG1 NOTCH3

2.07e-0684324C0334588
DiseaseGlioblastoma Multiforme

FAT1 NOTCH1 JAG1 NOTCH3

6.29e-06111324C1621958
Diseaseadenocarcinoma (implicated_via_orthology)

NOTCH1 NOTCH3

2.38e-057322DOID:299 (implicated_via_orthology)
Diseasecentral nervous system cancer (implicated_via_orthology)

NOTCH1 NOTCH3

2.38e-057322DOID:3620 (implicated_via_orthology)
DiseaseMalignant neoplasm of skin

NOTCH1 NOTCH3 NOTCH4

3.61e-0559323C0007114
DiseaseSkin Neoplasms

NOTCH1 NOTCH3 NOTCH4

3.61e-0559323C0037286
DiseaseSchizophrenia

LRP1 LRP2 LAMA2 KCNN3 ELAVL2 JAG1 NOTCH4

3.67e-05883327C0036341
Diseasehemangiopericytoma (is_marker_for)

NOTCH1 NOTCH4

4.08e-059322DOID:264 (is_marker_for)
Diseaseoctadecanedioate measurement

LAMA2 LAMC3

5.10e-0510322EFO_0021056
DiseaseCharcot-Marie-Tooth disease (is_implicated_in)

FBLN5 JAG1

7.47e-0512322DOID:10595 (is_implicated_in)
Diseaseobesity (implicated_via_orthology)

NOTCH1 NOTCH3 NOTCH4 ITPR1

8.40e-05215324DOID:9970 (implicated_via_orthology)
DiseaseMigraine Disorders

LRP1 NOTCH3

8.82e-0513322C0149931
DiseaseSquamous cell carcinoma of esophagus

FAT1 NOTCH1 NOTCH3

1.50e-0495323C0279626
DiseaseAdenoid Cystic Carcinoma

FAT1 NOTCH1 JAG1

1.74e-04100323C0010606
DiseaseSplenomegaly

KCNN3 NOTCH1

2.60e-0422322C0038002
Diseasecongenital heart disease (is_implicated_in)

NOTCH1 JAG1

3.10e-0424322DOID:1682 (is_implicated_in)
DiseaseSquamous cell carcinoma

NOTCH1 NOTCH3 NOTCH4

3.29e-04124323C0007137
Diseasepallidum volume change measurement, age at assessment

FBLN5 SLIT1

3.37e-0425322EFO_0008007, EFO_0021494
Diseaseurate measurement

LRP1 LRP2 THBS3 PHF21A JAG1 CEMIP

3.53e-04895326EFO_0004531
Diseasebrain cancer (implicated_via_orthology)

NOTCH1 NOTCH3

3.64e-0426322DOID:1319 (implicated_via_orthology)
DiseaseEncephalopathies

LAMC3 NOTCH3

3.93e-0427322C0085584
Diseaselung small cell carcinoma (is_implicated_in)

LAMC2 FAT1

4.23e-0428322DOID:5409 (is_implicated_in)
Diseasecolorectal cancer (implicated_via_orthology)

NOTCH1 NOTCH3

4.86e-0430322DOID:9256 (implicated_via_orthology)
Diseaseintestinal cancer (implicated_via_orthology)

NOTCH1 NOTCH3

5.54e-0432322DOID:10155 (implicated_via_orthology)
Diseaseosteoarthritis (is_marker_for)

HBP1 JAG1

6.63e-0435322DOID:8398 (is_marker_for)
Diseaseendometrial cancer (is_marker_for)

NOTCH1 NOTCH4

6.63e-0435322DOID:1380 (is_marker_for)
Diseasehematocrit

LRP2 FAT1 THBS3 JAG1 NOTCH4 ITPR1

6.73e-041011326EFO_0004348
DiseaseMalignant neoplasm of breast

LAMA2 THBS3 NOTCH1 JAG1 NOTCH3 NOTCH4

9.22e-041074326C0006142

Protein segments in the cluster

PeptideGeneStartEntry
TNCPSQCNENPVDGH

ADAM7

631

Q9H2U9
ANPNNNLINCAAAGS

CEMIP

676

Q8WUJ3
SQAPGNQRPNNTCCF

RGS17

16

Q9UGC6
DCASNPCQNGGVCNP

FAT1

4016

Q14517
PNCQTNINECASNPC

NOTCH1

786

P46531
NINECASNPCLNQGT

NOTCH1

791

P46531
QFASCENNPCGNGAT

EYS

2371

Q5T1H1
LPGACNIPANVSNCN

KRT31

31

Q15323
VDNPGCNEVNSVNCN

ITPR1

201

Q14643
CANNSTCTVNQGNQP

LRP1

4276

Q07954
CPCPSSGDEQQQQQQ

KCNN3

21

Q9UGI6
NDCDPNPCLNGGSCQ

NOTCH3

851

Q9UM47
APSPSSQSCTANCNQ

PHF21A

661

Q96BD5
LPGACNIPANVSNCN

KRT33A

31

O76009
PQCRICNQNSSNPNQ

LAMA2

81

P24043
SNACNQPTHPNGDCS

LRP2

971

P98164
NNPQAQQGCSCGSSF

ISCA2

136

Q86U28
DGCQNNCPACTPGQA

FCGBP

651

Q9Y6R7
QNCCPQLQEHSQQPC

DHX58

201

Q96C10
CNNTANGPTTINNNC

ELAVL2

11

Q12926
QCNENLPSSPGYNSC

HBP1

36

O60381
PCQCNNNVDPSASGN

LAMC2

516

Q13753
CLPSPGNAQAQCTNG

FBLN5

16

Q9UBX5
PNPCQNGAQCYNRAS

JAG1

531

P78504
TNINDCSQNPCHNGG

JAG1

666

P78504
QLNCSNSCPQPQNSS

ICAM4

66

Q14773
DPCQNAQLCQNGGSC

NOTCH4

66

Q99466
NPDNCVSHQCQNGGT

NOTCH4

276

Q99466
RSSPCANGGQCQDQP

NOTCH4

556

Q99466
NVPGNCSENPCQNGG

SNED1

1306

Q8TER0
NTLQCNASGCPAQDP

TAS1R3

406

Q7RTX0
TQTGPNQAACNCLPA

STAB2

1531

Q8WWQ8
GDACDNCPNVPNNDQ

THBS3

536

P49746
SSPCQNQGTCHNDPL

SLIT1

931

O75093
CQNGANCVDQGNRPV

SLIT1

1136

O75093
LPGACNIPANVSNCN

KRT33B

31

Q14525
PCHQCQCSGNVDPNA

LAMC3

806

Q9Y6N6