Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainTSP_1

CILP2 SSPOP

2.48e-0363222PF00090
DomainTSP1

CILP2 SSPOP

2.63e-0365222SM00209
DomainTSP1_rpt

CILP2 SSPOP

2.63e-0365222IPR000884
DomainTSP1

CILP2 SSPOP

2.63e-0365222PS50092
Pubmed

Birth and rapid subcellular adaptation of a hominoid-specific CDC14 protein.

CDC14C CDC14B

5.80e-07227218547142
Pubmed

Overexpression of CDC14B causes mitotic arrest and inhibits zygotic genome activation in mouse preimplantation embryos.

CDC14C CDC14B

5.80e-07227219923902
Pubmed

The Cdc14B phosphatase displays oncogenic activity mediated by the Ras-Mek signaling pathway.

CDC14C CDC14B

5.80e-07227221502810
Pubmed

Cdc14b regulates mammalian RNA polymerase II and represses cell cycle transcription.

CDC14C CDC14B

1.74e-06327222355704
Pubmed

Early-onset aging and defective DNA damage response in Cdc14b-deficient mice.

CDC14C CDC14B

1.74e-06327221262768
Pubmed

CDC14B acts through FZR1 (CDH1) to prevent meiotic maturation of mouse oocytes.

CDC14C CDC14B

1.74e-06327219129509
Pubmed

Cdc14A and Cdc14B Redundantly Regulate DNA Double-Strand Break Repair.

CDC14C CDC14B

1.74e-06327226283732
Pubmed

CDC14A phosphatase is essential for hearing and male fertility in mouse and human.

CDC14C CDC14B

3.48e-06427229293958
Pubmed

Mis12 controls cyclin B1 stabilization via Cdc14B-mediated APC/CCdh1 regulation during meiotic G2/M transition in mouse oocytes.

CDC14C CDC14B

3.48e-06427232341029
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

ZNF771 ZNF469 ZNF526 PARS2 NAF1 PRSS56

1.79e-04111627631753913
Pubmed

BTB-ZF factors recruit the E3 ligase cullin 3 to regulate lymphoid effector programs.

RORC DHX9

2.66e-043127223086144
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

SAC3D1 RBM15 REXO1 NAF1 DHX9

2.90e-0477427515302935
Pubmed

Regulation of epidermal differentiation through KDF1-mediated deubiquitination of IKKα.

ZNF771 RBM15 DHX9

3.76e-0418227332239614
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF747 ZNF771 ZNF469 ZNF526

4.84e-0371818428
Diseasecholangiocarcinoma (is_marker_for)

PRSS56 WNT9A

1.35e-0364252DOID:4947 (is_marker_for)
Diseaseaxial length measurement

ZNF469 PRSS56

1.94e-0377252EFO_0005318
Diseaseempathy measurement

PRSS56 WNT9A

9.07e-03170252EFO_0009183

Protein segments in the cluster

PeptideGeneStartEntry
PDRFIAFCGPHSRAR

CDC14B

221

O60729
PDRFIAFCGPHSRAR

CDC14C

191

A4D256
DAFGHRAPDPLRGAR

RBM15

551

Q96T37
APGGRGCDRPRADHA

LBHD1

226

Q9BQE6
EGRCRFGARCRQPHP

LENG9

51

Q96B70
RRPGPDCRAKSRGRH

DCAF10

96

Q5QP82
RAVACAPHCFGPRLR

KIF25-AS1

16

Q9Y6Z4
LRRCYARGAGPHPRQ

SAC3D1

211

A6NKF1
RKGRAGRVRPGFCFH

DHX9

761

Q08211
QHRSHECRGSGRPRP

PRSS56

61

P0CW18
GDVLGSSRPHRRRPC

PWWP3A

141

Q2TAK8
PCRFHHCAPRRGRRL

PARS2

26

Q7L3T8
GGPCRRPYCHFRHRG

REXO1

21

Q8N1G1
HAAAPDPKCRSGGRR

RNF19B

16

Q6ZMZ0
GPARCHRHRFCARSP

SSPOP

3201

A2VEC9
RHHPGARLARPDGCN

SSPOP

3376

A2VEC9
EPCRRGRHRVPLASG

TMEM132A

746

Q24JP5
GHAARCAARARPPRC

NTN5

161

Q8WTR8
APRRLPGTARARCGH

RNF227

31

A6NIN4
SCGPGRRLRRRHCPS

CILP2

161

Q8IUL8
RPHACPDCGRAFARR

ZNF771

61

Q7L3S4
PDRCGLRFEEHRHPG

RORC

226

P51449
HRGERPHRCPECGRA

ZNF747

231

Q9BV97
RRAPGARGRCAPDHF

ZNF469

3596

Q96JG9
AGRFSPGTAGRRCHR

WNT9A

301

O14904
RRAVHGPPERRHRCG

ZNF526

461

Q8TF50
RAGGRDFPCHRAALS

KLHL35

46

Q6PF15
GFSRARYPRSCHGRP

NAF1

376

Q96HR8