Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	extracellular matrix structural constituent	HSPG2 COL11A2 FBN1 PXDN LAMA2 LTBP4 AGRN	1.23e-05	188	82	7	GO:0005201
GeneOntologyCellularComponent	extracellular matrix	ADAMTS10 HSPG2 EYS COL11A2 FBN1 PXDN ADAMTS7 CCBE1 LAMA2 LRRTM1 LTBP4 TF AGRN	1.55e-06	656	82	13	GO:0031012
GeneOntologyCellularComponent	external encapsulating structure	ADAMTS10 HSPG2 EYS COL11A2 FBN1 PXDN ADAMTS7 CCBE1 LAMA2 LRRTM1 LTBP4 TF AGRN	1.60e-06	658	82	13	GO:0030312
GeneOntologyCellularComponent	basement membrane	HSPG2 FBN1 PXDN LAMA2 TF AGRN	8.51e-06	122	82	6	GO:0005604
GeneOntologyCellularComponent	microfibril	ADAMTS10 FBN1 LTBP4	1.62e-05	13	82	3	GO:0001527
GeneOntologyCellularComponent	blood microparticle	BCHE HSPA1L TF HSPA2 HSPA6 DNPEP	2.19e-05	144	82	6	GO:0072562
GeneOntologyCellularComponent	collagen-containing extracellular matrix	ADAMTS10 HSPG2 EYS COL11A2 FBN1 PXDN LAMA2 LTBP4 TF AGRN	4.20e-05	530	82	10	GO:0062023
GeneOntologyCellularComponent	endoplasmic reticulum lumen	COL11A2 FBN1 ADAMTS7 PTPRN2 BCHE TF TSPAN5	3.28e-04	332	82	7	GO:0005788
GeneOntologyCellularComponent	nuclear envelope lumen	IGF2R BCHE	1.34e-03	14	82	2	GO:0005641
HumanPheno	Narrow chest	HSPG2 IFT140 COL11A2 FBN1 CCBE1 AGRN DDX3X	1.10e-05	133	31	7	HP:0000774
HumanPheno	Thoracic hypoplasia	HSPG2 IFT140 COL11A2 FBN1 CCBE1 AGRN DDX3X	2.76e-05	153	31	7	HP:0005257
HumanPheno	Pectus carinatum	HSPG2 COL11A2 FBN1 ATAD3A AGRN TBCD KIF7	7.30e-05	178	31	7	HP:0000768
HumanPheno	Abnormal malar bone morphology	HSPG2 COL11A2 FBN1 CCBE1 HDAC8 PDZD8 LTBP4 KIF7	8.62e-05	249	31	8	HP:0012369
HumanPheno	Abnormal zygomatic arch morphology	HSPG2 COL11A2 FBN1 CCBE1 HDAC8 PDZD8 LTBP4 KIF7	8.86e-05	250	31	8	HP:0005557
HumanPheno	Abnormal zygomatic bone morphology	HSPG2 COL11A2 FBN1 CCBE1 HDAC8 PDZD8 LTBP4 KIF7	8.86e-05	250	31	8	HP:0010668
HumanPheno	Aplasia/Hypoplasia involving bones of the skull	ADAMTS10 CACNA1C HSPG2 IFT140 KMT2D COL11A2 FBN1 RTEL1 ATAD3A HDAC8 LTBP4 AGRN DDX3X TBCD KIF7	9.93e-05	915	31	15	HP:0009116
HumanPheno	Hypoplastic facial bones	ADAMTS10 HSPG2 COL11A2 FBN1 RTEL1 CCBE1 PDZD8 LTBP4 KIF7	1.04e-04	331	31	9	HP:0002692
HumanPheno	Aplasia/Hypoplasia of facial bones	ADAMTS10 HSPG2 COL11A2 FBN1 RTEL1 CCBE1 PDZD8 LTBP4 KIF7	1.06e-04	332	31	9	HP:0034261
HumanPheno	Broad skull	ADAMTS10 FBN1	1.07e-04	3	31	2	HP:0002682
HumanPheno	Abnormal midface morphology	ADAMTS10 HSPG2 IFT140 KMT2D COL11A2 FBN1 RTEL1 CCBE1 HDAC8 PDZD8 LTBP4 DDX3X KIF7	1.12e-04	704	31	13	HP:0000309
HumanPheno	Lens dislocation	ADAMTS10 HSPG2 FBN1 SUOX	1.17e-04	43	31	4	HP:0000665
HumanPheno	Ectopia lentis	ADAMTS10 HSPG2 FBN1 SUOX	1.17e-04	43	31	4	HP:0001083
HumanPheno	Abnormality of the jaws	ADAMTS10 CACNA1C HSPG2 IFT140 KMT2D COL11A2 FBN1 RTEL1 ATAD3A CCBE1 HDAC8 LAMA2 LTBP4 AGRN DDX3X TBCD KIF7	1.23e-04	1175	31	17	HP:0000209
HumanPheno	Abnormal jaw morphology	ADAMTS10 CACNA1C HSPG2 IFT140 KMT2D COL11A2 FBN1 RTEL1 ATAD3A CCBE1 HDAC8 LAMA2 LTBP4 AGRN DDX3X TBCD KIF7	1.24e-04	1176	31	17	HP:0030791
HumanPheno	Broad metacarpals	ADAMTS10 IFT140 FBN1	1.85e-04	19	31	3	HP:0001230
HumanPheno	Microspherophakia	ADAMTS10 FBN1	2.13e-04	4	31	2	HP:0030961
HumanPheno	Micromelia	HSPG2 IFT140 COL11A2 HDAC8 KIF7	2.23e-04	94	31	5	HP:0002983
HumanPheno	Conductive hearing impairment	HSPG2 IFT140 EYS KMT2D COL11A2 FBN1 CCBE1 HDAC8 KIF7	2.60e-04	373	31	9	HP:0000405
HumanPheno	Abnormality of globe location or size	ADAMTS10 CACNA1C HSPG2 IFT140 KMT2D COL11A2 FBN1 PXDN SUOX ATAD3A CCBE1 HDAC8 PDZD8 LTBP4 DDX3X TBCD KIF7	2.65e-04	1246	31	17	HP:0000489
HumanPheno	Abnormality of globe location	ADAMTS10 CACNA1C HSPG2 IFT140 KMT2D COL11A2 FBN1 SUOX ATAD3A CCBE1 HDAC8 PDZD8 LTBP4 DDX3X TBCD KIF7	2.78e-04	1122	31	16	HP:0100886
HumanPheno	Abnormal dental morphology	ADAMTS10 CACNA1C IFT140 KMT2D FBN1 EDAR RTEL1 CCBE1	3.08e-04	299	31	8	HP:0006482
HumanPheno	Aplasia/hypoplasia affecting bones of the axial skeleton	ADAMTS10 CACNA1C HSPG2 IFT140 KMT2D COL11A2 FBN1 RTEL1 ATAD3A HDAC8 LTBP4 AGRN DDX3X TBCD KIF7	3.09e-04	1008	31	15	HP:0009122
HumanPheno	Abnormal sternum morphology	HSPG2 IFT140 COL11A2 FBN1 ATAD3A CCBE1 HDAC8 AGRN TBCD KIF7	3.25e-04	474	31	10	HP:0000766
HumanPheno	Functional abnormality of the middle ear	HSPG2 IFT140 EYS KMT2D COL11A2 FBN1 CCBE1 HDAC8 KIF7	3.37e-04	386	31	9	HP:0011452
HumanPheno	Spherophakia	ADAMTS10 FBN1	3.54e-04	5	31	2	HP:0034375
HumanPheno	Pulmonary arterial hypertension	JAK2 CACNA1C HSPG2 KMT2D FBN1 LAMA2	3.59e-04	162	31	6	HP:0002092
HumanPheno	Pre-capillary pulmonary hypertension	JAK2 CACNA1C HSPG2 KMT2D FBN1 LAMA2	3.59e-04	162	31	6	HP:0033578
HumanPheno	Elevated pulmonary artery pressure	JAK2 CACNA1C HSPG2 KMT2D FBN1 LAMA2	3.83e-04	164	31	6	HP:0004890
HumanPheno	Narrow mouth	CACNA1C HSPG2 COL11A2 FBN1 ATAD3A CCBE1 KIF7	4.03e-04	234	31	7	HP:0000160
HumanPheno	Talipes equinovalgus	HSPG2 IFT140 FBN1 ATAD3A CCBE1 HDAC8	4.09e-04	166	31	6	HP:0001772
HumanPheno	Malar flattening	HSPG2 COL11A2 FBN1 CCBE1 PDZD8 LTBP4 KIF7	4.70e-04	240	31	7	HP:0000272
HumanPheno	Broad ribs	ADAMTS10 COL11A2 FBN1	5.41e-04	27	31	3	HP:0000885
HumanPheno	Depressed nasal bridge	ADAMTS10 CACNA1C HSPG2 IFT140 KMT2D COL11A2 FBN1 EDAR CCBE1 HDAC8 KIF7	6.04e-04	612	31	11	HP:0005280
HumanPheno	Flattened nasal bridge	ADAMTS10 CACNA1C HSPG2 IFT140 KMT2D COL11A2 FBN1 EDAR CCBE1 HDAC8 KIF7	6.04e-04	612	31	11	HP:0000425
HumanPheno	Broad foot	ADAMTS10 HSPG2 IFT140 FBN1 CCBE1 HDAC8	6.12e-04	179	31	6	HP:0001769
HumanPheno	Aplasia/hypoplasia involving the skeleton	MAG ADAMTS10 CACNA1C HSPG2 IFT140 KMT2D COL11A2 FBN1 RTEL1 ATAD3A CCBE1 HDAC8 LTBP4 AGRN DDX3X TBCD KIF7	6.90e-04	1343	31	17	HP:0009115
HumanPheno	Micrognathia	CACNA1C HSPG2 IFT140 KMT2D COL11A2 FBN1 ATAD3A HDAC8 LTBP4 AGRN DDX3X TBCD KIF7	7.06e-04	843	31	13	HP:0000347
HumanPheno	Aplasia/Hypoplasia of the mandible	CACNA1C HSPG2 IFT140 KMT2D COL11A2 FBN1 ATAD3A HDAC8 LTBP4 AGRN DDX3X TBCD KIF7	7.23e-04	845	31	13	HP:0009118
HumanPheno	Postnatal growth retardation	CACNA1C KMT2D RTEL1 CCBE1 HDAC8 DDX3X KIF7	7.26e-04	258	31	7	HP:0008897
MousePheno	heart hemorrhage	HSPG2 IFT140 FBN1 IGF2R RTEL1	6.76e-06	55	68	5	MP:0009698
Domain	LamG	HSPG2 EYS FAT1 COL11A2 LAMA2 AGRN	3.16e-08	44	80	6	SM00282
Domain	Laminin_G_1	HSPG2 EYS LAMA2 AGRN	1.01e-07	11	80	4	PF00054
Domain	Laminin_G	HSPG2 EYS FAT1 COL11A2 LAMA2 AGRN	1.73e-07	58	80	6	IPR001791
Domain	LAM_G_DOMAIN	HSPG2 EYS FAT1 LAMA2 AGRN	5.71e-07	38	80	5	PS50025
Domain	Laminin_G_2	HSPG2 EYS FAT1 COL11A2 LAMA2	7.43e-07	40	80	5	PF02210
Domain	EGF_CA	HSPG2 EYS FAT1 FBN1 CCBE1 LTBP4 AGRN	9.13e-07	122	80	7	SM00179
Domain	EGF-like_Ca-bd_dom	HSPG2 EYS FAT1 FBN1 CCBE1 LTBP4 AGRN	1.02e-06	124	80	7	IPR001881
Domain	-	HSPG2 EYS FAT1 COL11A2 LAMA2 AGRN	3.28e-06	95	80	6	2.60.120.200
Domain	EGF	HSPG2 EYS FAT1 FBN1 CCBE1 LAMA2 LTBP4 AGRN	7.41e-06	235	80	8	SM00181
Domain	EGF-like_dom	HSPG2 EYS FAT1 FBN1 CCBE1 LAMA2 LTBP4 AGRN	1.13e-05	249	80	8	IPR000742
Domain	EGF_1	HSPG2 EYS FAT1 FBN1 CCBE1 LAMA2 LTBP4 AGRN	1.34e-05	255	80	8	PS00022
Domain	EGF-like_CS	HSPG2 EYS FAT1 FBN1 CCBE1 LAMA2 LTBP4 AGRN	1.59e-05	261	80	8	IPR013032
Domain	-	HSPA1L HSPA2 HSPA6	1.62e-05	12	80	3	2.60.34.10
Domain	HSP70_peptide-bd	HSPA1L HSPA2 HSPA6	1.62e-05	12	80	3	IPR029047
Domain	EGF_2	HSPG2 EYS FAT1 FBN1 CCBE1 LAMA2 LTBP4 AGRN	1.77e-05	265	80	8	PS01186
Domain	-	HSPA1L HSPA2 HSPA6	2.10e-05	13	80	3	1.20.1270.10
Domain	Heat_shock_70_CS	HSPA1L HSPA2 HSPA6	2.10e-05	13	80	3	IPR018181
Domain	HSP70_C	HSPA1L HSPA2 HSPA6	2.10e-05	13	80	3	IPR029048
Domain	HSP70	HSPA1L HSPA2 HSPA6	4.07e-05	16	80	3	PF00012
Domain	HSP70_2	HSPA1L HSPA2 HSPA6	4.93e-05	17	80	3	PS00329
Domain	HSP70_3	HSPA1L HSPA2 HSPA6	4.93e-05	17	80	3	PS01036
Domain	HSP70_1	HSPA1L HSPA2 HSPA6	4.93e-05	17	80	3	PS00297
Domain	Hsp_70_fam	HSPA1L HSPA2 HSPA6	5.90e-05	18	80	3	IPR013126
Domain	EGF_Ca-bd_CS	EYS FAT1 FBN1 CCBE1 LTBP4	6.02e-05	97	80	5	IPR018097
Domain	EGF_CA	EYS FAT1 FBN1 CCBE1 LTBP4	6.63e-05	99	80	5	PS01187
Domain	EGF_3	HSPG2 EYS FAT1 FBN1 CCBE1 LTBP4 AGRN	6.65e-05	235	80	7	PS50026
Domain	ASX_HYDROXYL	EYS FAT1 FBN1 CCBE1 LTBP4	6.96e-05	100	80	5	PS00010
Domain	EGF-type_Asp/Asn_hydroxyl_site	EYS FAT1 FBN1 CCBE1 LTBP4	9.18e-05	106	80	5	IPR000152
Domain	Ig_I-set	MAG HSPG2 PXDN IGDCC3 SIGLEC1 IGDCC4	1.65e-04	190	80	6	IPR013098
Domain	I-set	MAG HSPG2 PXDN IGDCC3 SIGLEC1 IGDCC4	1.65e-04	190	80	6	PF07679
Domain	EGF_LAM_2	HSPG2 LAMA2 AGRN	2.83e-04	30	80	3	PS50027
Domain	EGF_LAM_1	HSPG2 LAMA2 AGRN	2.83e-04	30	80	3	PS01248
Domain	ConA-like_dom	HSPG2 EYS FAT1 COL11A2 LAMA2 AGRN	3.54e-04	219	80	6	IPR013320
Domain	TB	FBN1 LTBP4	3.75e-04	7	80	2	PF00683
Domain	Laminin_EGF	HSPG2 LAMA2 AGRN	4.49e-04	35	80	3	PF00053
Domain	EGF_Lam	HSPG2 LAMA2 AGRN	4.49e-04	35	80	3	SM00180
Domain	LAMININ_IVA	HSPG2 LAMA2	4.99e-04	8	80	2	PS51115
Domain	Laminin_B	HSPG2 LAMA2	4.99e-04	8	80	2	PF00052
Domain	-	FBN1 LTBP4	4.99e-04	8	80	2	3.90.290.10
Domain	LamB	HSPG2 LAMA2	4.99e-04	8	80	2	SM00281
Domain	Laminin_IV	HSPG2 LAMA2	4.99e-04	8	80	2	IPR000034
Domain	EGF_CA	FAT1 FBN1 CCBE1 LTBP4	5.08e-04	86	80	4	PF07645
Domain	IGc2	MAG HSPG2 PXDN IGDCC3 SIGLEC1 IGDCC4	5.15e-04	235	80	6	SM00408
Domain	Ig_sub2	MAG HSPG2 PXDN IGDCC3 SIGLEC1 IGDCC4	5.15e-04	235	80	6	IPR003598
Domain	Growth_fac_rcpt_	HSPG2 EYS FAT1 FBN1 LTBP4	5.54e-04	156	80	5	IPR009030
Domain	Laminin_EGF	HSPG2 LAMA2 AGRN	5.73e-04	38	80	3	IPR002049
Domain	TB	FBN1 LTBP4	6.40e-04	9	80	2	PS51364
Domain	TB_dom	FBN1 LTBP4	6.40e-04	9	80	2	IPR017878
Domain	SEA	HSPG2 AGRN	1.59e-03	14	80	2	SM00200
Domain	EGF	HSPG2 EYS FAT1 AGRN	2.10e-03	126	80	4	PF00008
Domain	PLAC	ADAMTS10 ADAMTS7	2.96e-03	19	80	2	PS50900
Domain	PLAC	ADAMTS10 ADAMTS7	2.96e-03	19	80	2	IPR010909
Domain	HEAT_REPEAT	MROH7 TBCD TANGO6	3.37e-03	70	80	3	PS50077
Domain	SEA	HSPG2 AGRN	3.96e-03	22	80	2	PF01390
Domain	ADAM_spacer1	ADAMTS10 ADAMTS7	4.32e-03	23	80	2	IPR010294
Pubmed	Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.	HSPG2 COL11A2 FBN1 PXDN LAMA2 LTBP4 AGRN	2.00e-07	175	82	7	28071719
Pubmed	Absence of acetylcholinesterase at the neuromuscular junctions of perlecan-null mice.	HSPG2 LAMA2 AGRN	4.39e-07	7	82	3	11802174
Pubmed	PML Recruits TET2 to Regulate DNA Modification and Cell Proliferation in Response to Chemotherapeutic Agent.	DCD HSPA1L TF HSPA6 DDX3X	5.54e-07	67	82	5	29735542
Pubmed	Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics.	HSPG2 COL11A2 FBN1 LAMA2 LTBP4 AGRN	8.41e-07	135	82	6	28675934
Pubmed	Proteomic analysis of microvesicles from plasma of healthy donors reveals high individual variability.	BCHE HSPA1L TF HSPA2 HSPA6 DNPEP	1.18e-06	143	82	6	22516433
Pubmed	Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins.	HSPG2 FBN1 RNPEP LAMA2 LTBP4 AGRN	1.33e-06	146	82	6	27068509
Pubmed	Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.	HSPG2 FBN1 PXDN ADAMTS7 LAMA2 LTBP4 AGRN	2.08e-06	248	82	7	24006456
Pubmed	Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.	HSPG2 SEMA4B CPNE9 LAMA2 BCHE TF PLXNB1	2.63e-06	257	82	7	16335952
Pubmed	Molecular dissection of laminin alpha 5 in vivo reveals separable domain-specific roles in embryonic development and kidney function.	HSPG2 LAMA2 AGRN	2.74e-06	12	82	3	16750824
Pubmed	ARMC5 is part of an RPB1-specific ubiquitin ligase implicated in adrenal hyperplasia.	RNPEP HSPA1L TF HSPA2 HSPA6 LRRC47	2.80e-06	166	82	6	35687106
Pubmed	The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.	HSPG2 FBN1 PXDN LAMA2 LTBP4 AGRN	2.90e-06	167	82	6	22159717
Pubmed	Glycoproteomics Reveals Decorin Peptides With Anti-Myostatin Activity in Human Atrial Fibrillation.	HSPG2 FBN1 LAMA2 LTBP4 AGRN	3.50e-06	97	82	5	27559042
Pubmed	Congenital Diaphragmatic Hernia Overview	KMT2D FBN1 HDAC8 LTBP4	4.34e-06	46	82	4	20301533
Pubmed	Large-scale proteomics and phosphoproteomics of urinary exosomes.	HSPG2 EYS FAT1 BTG2 IGF2R RNPEP DCD AKR1A1 TF HSPA2 STK24 DDX3X	4.58e-06	1016	82	12	19056867
Pubmed	Genomic structure and chromosomal localization of the mouse gene Punc.	IGDCC3 IGDCC4	5.49e-06	2	82	2	9922388
Pubmed	Agrin and perlecan mediate tumorigenic processes in oral squamous cell carcinoma.	HSPG2 AGRN	5.49e-06	2	82	2	25506919
Pubmed	Comparative immunolocalisation of fibrillin-1 and perlecan in the human foetal, and HS-deficient hspg2 exon 3 null mutant mouse intervertebral disc.	HSPG2 FBN1	5.49e-06	2	82	2	23104139
Pubmed	ADAMTS10 protein interacts with fibrillin-1 and promotes its deposition in extracellular matrix of cultured fibroblasts.	ADAMTS10 FBN1	5.49e-06	2	82	2	21402694
Pubmed	Amelioration of laminin-alpha2-deficient congenital muscular dystrophy by somatic gene transfer of miniagrin.	LAMA2 AGRN	5.49e-06	2	82	2	16103356
Pubmed	The Fbn1 gene variant governs passive ascending aortic mechanics in the mgΔlpn mouse model of Marfan syndrome when superimposed to perlecan haploinsufficiency.	HSPG2 FBN1	5.49e-06	2	82	2	38545339
Pubmed	Neither the butyrylcholinesterase K variant nor transferrin C2 variant confers a risk for Alzheimer's disease in Koreans.	BCHE TF	5.49e-06	2	82	2	11725818
Pubmed	CD169⁺ macrophages provide a niche promoting erythropoiesis under homeostasis and stress.	JAK2 SIGLEC1	5.49e-06	2	82	2	23502962
Pubmed	Is HSPG2 a modifier gene for Marfan syndrome?	HSPG2 FBN1	5.49e-06	2	82	2	32514132
Pubmed	Polymorphisms in genes coding for HSP-70 are associated with gastric cancer and duodenal ulcer in a population at high risk of gastric cancer in Costa Rica.	HSPA1L HSPA2	5.49e-06	2	82	2	24051039
Pubmed	Microfibrils at basement membrane zones interact with perlecan via fibrillin-1.	HSPG2 FBN1	5.49e-06	2	82	2	15657057
Pubmed	Upregulation of RIN3 induces endosomal dysfunction in Alzheimer's disease.	MAG DCD HSPA1L HSPA2 PYCR3 DDX3X TBCD LRRC47	6.68e-06	418	82	8	32552912
Pubmed	Patterns of laminins and integrins in the embryonic ventricular zone of the CNS.	HSPG2 LAMA2 AGRN	6.92e-06	16	82	3	17948866
Pubmed	Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.	HSPG2 SEMA4B FAT1 FBN1 IGF2R ATAD3A MTIF2 SEC24B PDZD8 OAT AGRN PYCR3 DDX3X DNPEP	7.01e-06	1451	82	14	30550785
Pubmed	Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.	JAK2 SEMA4B FAT1 IGF2R RNPEP OAT AKR1A1 HSPA1L HSPA2 HSPA6 PYCR3 LRRC47	7.09e-06	1061	82	12	33845483
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	JAK2 HSPG2 SEMA4B FAT1 KMT2D IGF2R ADAMTS7 PDZD8 LTBP4 AGRN TBCD RAB11FIP3	1.07e-05	1105	82	12	35748872
Pubmed	TRIM21-mediated proteasomal degradation of SAMHD1 regulates its antiviral activity.	OAT TF DNPEP	1.19e-05	19	82	3	31797533
Pubmed	Adamts10 inactivation in mice leads to persistence of ocular microfibrils subsequent to reduced fibrillin-2 cleavage.	ADAMTS10 FBN1	1.64e-05	3	82	2	30201140
Pubmed	GWAS of butyrylcholinesterase activity identifies four novel loci, independent effects within BCHE and secondary associations with metabolic risk factors.	RNPEP BCHE	1.64e-05	3	82	2	21862451
Pubmed	Radiogenomics in head and neck cancer: correlation of radiomic heterogeneity and somatic mutations in TP53, FAT1 and KMT2D.	FAT1 KMT2D	1.64e-05	3	82	2	31123786
Pubmed	Breast cancer cells promote CD169+ macrophage-associated immunosuppression through JAK2-mediated PD-L1 upregulation on macrophages.	JAK2 SIGLEC1	1.64e-05	3	82	2	31865052
Pubmed	Association of hsp70 polymorphisms with risk of noise-induced hearing loss in Chinese automobile workers.	HSPA1L HSPA2	1.64e-05	3	82	2	17009596
Pubmed	Sialoadhesin, myelin-associated glycoprotein and CD22 define a new family of sialic acid-dependent adhesion molecules of the immunoglobulin superfamily.	MAG SIGLEC1	1.64e-05	3	82	2	7533044
Pubmed	The diverse members of the mammalian HSP70 machine show distinct chaperone-like activities.	HSPA1L HSPA2 HSPA6	2.16e-05	23	82	3	21231916
Pubmed	SARS-CoV-2 N Protein Antagonizes Stress Granule Assembly and IFN Production by Interacting with G3BPs to Facilitate Viral Replication.	PPAN DCD ATAD3A HNRNPLL DDX3X LRRC47	2.57e-05	245	82	6	35652658
Pubmed	Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.	ADAMTS10 FAT1 MYG1 PXDN PGGHG TTL EXO1 LAMA2 ARHGAP45 HSPA2 AGRN DNPEP	2.72e-05	1215	82	12	15146197
Pubmed	Conditional deletion of beta1-integrin in astroglia causes partial reactive gliosis.	MAG HSPG2 LAMA2	2.80e-05	25	82	3	19373938
Pubmed	Quantitative Proteomics Reveals Dynamic Interactions of the Minichromosome Maintenance Complex (MCM) in the Cellular Response to Etoposide Induced DNA Damage.	HSPG2 CPNE9 DCD ATAD3A SEC24B HSPA1L HSPA2 HSPA6 DDX3X DNPEP	2.97e-05	844	82	10	25963833
Pubmed	Latent transforming growth factor beta-binding protein 1 interacts with fibrillin and is a microfibril-associated protein.	FBN1 LTBP4	3.28e-05	4	82	2	12429738
Pubmed	Weill-Marchesani Syndrome	ADAMTS10 FBN1	3.28e-05	4	82	2	20301293
Pubmed	Genetic factors determine extent of bone loss in inflammatory bowel disease.	HSPA1L HSPA2	3.28e-05	4	82	2	11040178
Pubmed	Variations in HSP70 genes associated with noise-induced hearing loss in two independent populations.	HSPA1L HSPA2	3.28e-05	4	82	2	18813331
Pubmed	Organisation of extracellular matrix proteins laminin and agrin in pericapillary basal laminae in mouse brain.	LAMA2 AGRN	3.28e-05	4	82	2	32072250
Pubmed	Cloning and expression of nope, a new mouse gene of the immunoglobulin superfamily related to guidance receptors.	IGDCC3 IGDCC4	3.28e-05	4	82	2	10708514
Pubmed	Epigenetic modulation of the renal β-adrenergic-WNK4 pathway in salt-sensitive hypertension.	HDAC8 WNK4	3.28e-05	4	82	2	21499270
Pubmed	Conjugation of LG domains of agrins and perlecan to polymerizing laminin-2 promotes acetylcholine receptor clustering.	HSPG2 AGRN	3.28e-05	4	82	2	16219760
Pubmed	An agrin minigene rescues dystrophic symptoms in a mouse model for congenital muscular dystrophy.	LAMA2 AGRN	3.28e-05	4	82	2	11565031
Pubmed	Identification of novel candidate genes in heterotaxy syndrome patients with congenital heart diseases by whole exome sequencing.	KMT2D KIF7	3.28e-05	4	82	2	32738303
Pubmed	A protein interaction network for the large conductance Ca(2+)-activated K(+) channel in the mouse cochlea.	RNPEP OAT HSPA1L TF HSPA2	3.63e-05	157	82	5	19423573
Pubmed	SERBP1 Promotes Stress Granule Clearance by Regulating 26S Proteasome Activity and G3BP1 Ubiquitination and Protects Male Germ Cells from Thermostimuli Damage.	HSPG2 IGF2R RNPEP ATAD3A OAT HSPA6 PYCR3 DDX3X TBCD TANGO6	4.14e-05	878	82	10	37223481
Pubmed	Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion.	SEMA4B PXDN IGDCC3 SIGLEC1 IGDCC4	4.21e-05	162	82	5	25826454
Pubmed	WWP2 is an E3 ubiquitin ligase for PTEN.	HSPA1L HSPA2 HSPA6	4.42e-05	29	82	3	21532586
Pubmed	Basement membrane assembly of the integrin α8β1 ligand nephronectin requires Fraser syndrome-associated proteins.	HSPG2 LAMA2 AGRN	4.42e-05	29	82	3	22613833
Pubmed	TGFβ attenuates cartilage extracellular matrix degradation via enhancing FBXO6-mediated MMP14 ubiquitination.	HSPG2 IGF2R PXDN BCHE AGRN	4.46e-05	164	82	5	32409323
Pubmed	Ski regulates Hippo and TAZ signaling to suppress breast cancer progression.	HSPG2 HSPA1L AGRN HSPA6	4.80e-05	84	82	4	25670202
Pubmed	The renal glomerulus of mice lacking s-laminin/laminin beta 2: nephrosis despite molecular compensation by laminin beta 1.	HSPG2 AGRN	5.47e-05	5	82	2	7670489
Pubmed	Capturing genes encoding membrane and secreted proteins important for mouse development.	FAT1 AGRN	5.47e-05	5	82	2	7604039
Pubmed	Development, composition, and structural arrangements of the ciliary zonule of the mouse.	HSPG2 FBN1	5.47e-05	5	82	2	23493297
Pubmed	CCT3 acts upstream of YAP and TFCP2 as a potential target and tumour biomarker in liver cancer.	ATAD3A OAT HSPA1L HSPA2 HSPA6 DDX3X	6.32e-05	288	82	6	31501420
Pubmed	Proteomic analysis of the 20S proteasome (PSMA3)-interacting proteins reveals a functional link between the proteasome and mRNA metabolism.	HSPA1L TF HSPA2 HNRNPLL	7.14e-05	93	82	4	22079093
Pubmed	Association analysis of HLA-class II and class III gene polymorphisms in the susceptibility to mediterranean visceral leishmaniasis.	HSPA1L HSPA2	8.19e-05	6	82	2	11334675
Pubmed	Histone deacetylases inhibitor sodium butyrate inhibits JAK2/STAT signaling through upregulation of SOCS1 and SOCS3 mediated by HDAC8 inhibition in myeloproliferative neoplasms.	JAK2 HDAC8	8.19e-05	6	82	2	23111066
Pubmed	Latent transforming growth factor beta-binding proteins and fibulins compete for fibrillin-1 and exhibit exquisite specificities in binding sites.	FBN1 LTBP4	8.19e-05	6	82	2	19349279
Pubmed	Susceptibility groups for Alzheimer's disease (OPTIMA cohort): integration of gene variants and biochemical factors.	BCHE TF	8.19e-05	6	82	2	17116317
Pubmed	Laminin alpha1 globular domains 4-5 induce fetal development but are not vital for embryonic basement membrane assembly.	HSPG2 AGRN	8.19e-05	6	82	2	15668394
Pubmed	A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.	HSPG2 TRAF1 PTPRN2 OAT LTBP4 HSPA2 AGRN HNRNPLL	9.54e-05	608	82	8	16713569
Pubmed	Proteomics characterization of extracellular space components in the human aorta.	HSPG2 FBN1 LTBP4 AGRN	9.85e-05	101	82	4	20551380
Pubmed	A targeted proteomic analysis of the ubiquitin-like modifier nedd8 and associated proteins.	HSPA1L HSPA6 DDX3X	1.00e-04	38	82	3	18247557
Pubmed	Proteomic identification of common SCF ubiquitin ligase FBXO6-interacting glycoproteins in three kinds of cells.	HSPG2 IGF2R PXDN ATAD3A OAT LTBP4 DDX3X LRRC47	1.01e-04	613	82	8	22268729
Pubmed	Ephrin-As, Eph receptors and integrin α3 interact and colocalise at membrane protrusions of U251MG glioblastoma cells.	TBC1D10B PXDN DCD RTEL1 DDX3X	1.06e-04	197	82	5	23686814
Pubmed	Association of gene polymorphisms with chronic kidney disease in Japanese individuals.	PXDN PTPRN2 TBCD	1.09e-04	39	82	3	19724895
Pubmed	Case-case genome-wide association analysis shows markers differentially associated with schizophrenia and bipolar disorder and implicates calcium channel genes.	CACNA1C PTPRN2	1.14e-04	7	82	2	21057379
Pubmed	A mutation in the nuclear pore complex gene Tmem48 causes gametogenesis defects in skeletal fusions with sterility (sks) mice.	HSPA1L HSPA2	1.14e-04	7	82	2	24045954
Pubmed	Comprehensive Characterization of Tissues Derived from Animals at Different Regenerative Stages: A Comparative Analysis between Fetal and Adult Mouse Skin.	HSPG2 AGRN	1.14e-04	7	82	2	37174615
Pubmed	Sequential Cyk-4 binding to ECT2 and FIP3 regulates cleavage furrow ingression and abscission during cytokinesis.	ECT2 RAB11FIP3	1.14e-04	7	82	2	18511905
Pubmed	PINK1 Content in Mitochondria is Regulated by ER-Associated Degradation.	RNPEP DCD ATAD3A HSPA1L HSPA2 HSPA6 DDX3X	1.37e-04	477	82	7	31300519
Pubmed	A mitochondrial FUNDC1/HSC70 interaction organizes the proteostatic stress response at the risk of cell morbidity.	HSPA2 HSPA6	1.52e-04	8	82	2	30591555
Pubmed	Extracellular Hsp90α and clusterin synergistically promote breast cancer epithelial-to-mesenchymal transition and metastasis via LRP1.	HSPG2 DCD TF	1.56e-04	44	82	3	31273033
Pubmed	Oxidative stress, telomere length and biomarkers of physical aging in a cohort aged 79 years from the 1932 Scottish Mental Survey.	HSPA1L TF HSPA2 HSPA6	1.74e-04	117	82	4	18977241
Pubmed	Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells.	ATAD3A HSPA1L HSPA2 HNRNPLL PYCR3 DDX3X TBCD LRRC47	1.76e-04	665	82	8	30457570
Pubmed	ZF21 is a new regulator of focal adhesion disassembly and a potential member of the spreading initiation center.	ATAD3A HSPA6 DDX3X	1.78e-04	46	82	3	20890123
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	TBC1D10B KMT2D IGF2R ZFYVE9 PTPRN2 SEC24B PDZD8 HSPA2 HSPA6 KIF7	1.79e-04	1049	82	10	27880917
Pubmed	Comparison of an expanded ataxia interactome with patient medical records reveals a relationship between macular degeneration and ataxia.	HSPG2 FBN1 LTBP4 AGRN	1.80e-04	118	82	4	21078624
Pubmed	A genetic association analysis of cognitive ability and cognitive ageing using 325 markers for 109 genes associated with oxidative stress or cognition.	HSPA1L TF HSPA2 HSPA6	1.85e-04	119	82	4	17601350
Pubmed	Semaphorin-Plexin Signaling Controls Mitotic Spindle Orientation during Epithelial Morphogenesis and Repair.	SEMA4B PLXNB1	1.96e-04	9	82	2	25892012
Pubmed	Chromosomal localization of five murine HSP70 gene family members: Hsp70-1, Hsp70-2, Hsp70-3, Hsc70t, and Grp78.	HSPA1L HSPA2	1.96e-04	9	82	2	8486356
Pubmed	Reciprocal regulation of human immunodeficiency virus-1 gene expression and replication by heat shock proteins 40 and 70.	HSPA2 HSPA6	1.96e-04	9	82	2	21763498
Pubmed	Comparative proteomic analysis of supportive and unsupportive extracellular matrix substrates for human embryonic stem cell maintenance.	HSPG2 FBN1 AGRN	2.29e-04	50	82	3	23658023
Pubmed	A regulatory circuit that involves HR23B and HDAC6 governs the biological response to HDAC inhibitors.	HSPA1L HSPA2 HSPA6	2.29e-04	50	82	3	23703321
Pubmed	Human immunodeficiency virus type 1 interaction with the membrane of CD4+ cells induces the synthesis and nuclear translocation of 70K heat shock protein.	HSPA2 HSPA6	2.44e-04	10	82	2	7906708
Pubmed	Specific incorporation of heat shock protein 70 family members into primate lentiviral virions.	HSPA2 HSPA6	2.44e-04	10	82	2	11932435
Pubmed	gp120 neurotoxicity fails to induce heat shock defenses, while the over expression of hsp70 protects against gp120.	HSPA2 HSPA6	2.44e-04	10	82	2	12832005
Pubmed	Identification and characterization of a novel human methyltransferase modulating Hsp70 protein function through lysine methylation.	HSPA2 HSPA6	2.44e-04	10	82	2	23921388
Pubmed	ADAMTS: a novel family of extracellular matrix proteases.	ADAMTS10 ADAMTS7	2.44e-04	10	82	2	11167130
Pubmed	CCND2, CTNNB1, DDX3X, GLI2, SMARCA4, MYC, MYCN, PTCH1, TP53, and MLL2 gene variants and risk of childhood medulloblastoma.	KMT2D DDX3X	2.44e-04	10	82	2	26290144
Pubmed	Loss of nidogen-1 and -2 results in syndactyly and changes in limb development.	HSPG2 AGRN	2.98e-04	11	82	2	17023412
Interaction	SOHLH1 interactions	IFT140 TRAF1 CPNE9 SUOX HSPA1L HSPA2 TANGO6	4.02e-07	115	81	7	int:SOHLH1
Interaction	ARMC5 interactions	RNPEP HSPA1L TF HSPA2 HSPA6 TBCD LRRC47	1.65e-05	201	81	7	int:ARMC5
Interaction	SOAT1 interactions	DCD PTPRN2 ATAD3A PDZD8 OAT SMPD3 ECT2 TSPAN5	2.44e-05	295	81	8	int:SOAT1
Interaction	PRODH interactions	HSPA1L HSPA2 HSPA6	3.37e-05	16	81	3	int:PRODH
Interaction	FBXO2 interactions	HSPG2 SEMA4B FBN1 IGF2R PXDN ADAMTS7 BCHE LTBP4 AGRN	3.99e-05	411	81	9	int:FBXO2
Cytoband	3q26.1-q26.2	BCHE ECT2	9.44e-06	3	82	2	3q26.1-q26.2
Cytoband	Ensembl 112 genes in cytogenetic band chr1q32	BTG2 RNPEP SERTAD4 CTSE	1.85e-03	290	82	4	chr1q32
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	MAG HSPG2 PXDN IGDCC3 SIGLEC1 IGDCC4	9.18e-06	161	55	6	593
GeneFamily	Heat shock 70kDa proteins	HSPA1L HSPA2 HSPA6	1.76e-05	17	55	3	583
GeneFamily	Blood group antigens\|CD molecules\|Proteoglycans	HSPG2 AGRN	1.89e-04	7	55	2	570
GeneFamily	Aminopeptidases\|CD molecules	RNPEP DNPEP	1.20e-03	17	55	2	104
GeneFamily	ADAM metallopeptidases with thrombospondin type 1 motif	ADAMTS10 ADAMTS7	1.50e-03	19	55	2	50
GeneFamily	CD molecules\|C2-set domain containing\|Sialic acid binding Ig like lectins	MAG SIGLEC1	3.26e-03	28	55	2	745
Coexpression	NABA_MATRISOME	ADAMTS10 HSPG2 SEMA4B EYS COL11A2 FBN1 PXDN ADAMTS7 CCBE1 MUC19 LAMA2 CTSE LTBP4 AGRN PLXNB1	6.00e-07	1026	82	15	M5889
Coexpression	NABA_CORE_MATRISOME	HSPG2 EYS COL11A2 FBN1 PXDN LAMA2 LTBP4 AGRN	2.42e-06	275	82	8	M5884
Coexpression	NABA_MATRISOME	ADAMTS10 HSPG2 SEMA4B COL11A2 FBN1 PXDN ADAMTS7 CCBE1 MUC19 LAMA2 CTSE LTBP4 AGRN PLXNB1	2.72e-06	1008	82	14	MM17056
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HRGL1	WSCD1 FAT1 SERTAD4 IGDCC3 TF FRMD3 TFF3 IGDCC4	1.87e-05	364	82	8	M39057
Coexpression	NABA_CORE_MATRISOME	HSPG2 COL11A2 FBN1 PXDN LAMA2 LTBP4 AGRN	2.24e-05	270	82	7	MM17057
Coexpression	NABA_ECM_GLYCOPROTEINS	EYS FBN1 PXDN LAMA2 LTBP4 AGRN	3.54e-05	196	82	6	M3008
Coexpression	GSE16522_MEMORY_VS_NAIVE_CD8_TCELL_DN	JAK2 KMT2D GARNL3 EXO1 LRRTM1 AGRN	3.96e-05	200	82	6	M3659
Coexpression	CUI_DEVELOPING_HEART_C5_VALVAR_CELL	BTG2 PXDN OAT LTBP4 HSPA2 HSPA6	4.54e-05	205	82	6	M39302
Coexpression	GRYDER_PAX3FOXO1_TOP_ENHANCERS	WSCD1 HSPG2 FAT1 PXDN OAT ECT2 STK24 TBCD	7.24e-05	441	82	8	M172
Coexpression	WILSON_PROTEASES_AT_TUMOR_BONE_INTERFACE_DN	ADAMTS7 CTSE	9.61e-05	5	82	2	M1794
Coexpression	FERRARI_RESPONSE_TO_FENRETINIDE_DN	HSPA2 TFF3	9.61e-05	5	82	2	M1585
Coexpression	NABA_MATRISOME_METASTATIC_LUNG_LYMPH_NODE_METASTASIS	COL11A2 PXDN AGRN	1.02e-04	29	82	3	MM17055
CoexpressionAtlas	FacebaseRNAseq_e9.5_Facial Mesenchyne_top-relative-expression-ranked_2500_k-means-cluster#2	ADAMTS10 JAK2 CACNA1C FBN1 HDAC8 SERTAD4 LAMA2 IGDCC3 OAT CTSE IGDCC4	3.15e-05	642	81	11	Facebase_RNAseq_e9.5_Facial Mesenchyne_2500_K2
CoexpressionAtlas	Stromal Cells, FRC.MLN, gp38+ CD31- CD140a+, Lymph Node, avg-5	HSPG2 FAT1 FBN1 PXDN LAMA2 OAT CD302 LTBP4 TF	7.04e-05	466	81	9	GSM777050_500
CoexpressionAtlas	FacebaseRNAseq_e9.5_Maxillary Arch_top-relative-expression-ranked_2500_k-means-cluster#1	ADAMTS10 JAK2 CACNA1C FBN1 SERTAD4 LAMA2 IGDCC3 PDZD8 OAT IGDCC4	8.00e-05	589	81	10	Facebase_RNAseq_e9.5_Maxillary Arch_2500_K1
CoexpressionAtlas	FacebaseRNAseq_e8.5_Paraxial Mesoderm_top-relative-expression-ranked_2500_k-means-cluster#4	ADAMTS10 JAK2 CACNA1C FBN1 HDAC8 SERTAD4 TTL LAMA2 IGDCC3 OAT IGDCC4	1.01e-04	731	81	11	Facebase_RNAseq_e8.5_Paraxial Mesoderm_2500_K4
ToppCell	facs-Lung-3m\|Lung / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MAG HSPG2 BTG2 FBN1 LAMA2 LTBP4 TFF3	7.45e-08	195	82	7	c4648c0332c3826776f9ad3f5f803dbac2b4c0c0
ToppCell	Transplant_Alveoli_and_parenchyma-Epithelial-Type_1_alveolar\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	HSPG2 PXDN PGGHG CTSE AGRN FRMD3	5.16e-07	160	82	6	58ed3a074932ccc951e07868dfdc61b99ae1cc2b
ToppCell	COVID-19-Heart-Fib_+_EC_+_Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CACNA1C HSPG2 FBN1 PXDN LAMA2 FRMD3	1.09e-06	182	82	6	fbd5e332df73bf7141c822fa67b76367dc962017
ToppCell	droplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HSPG2 FBN1 SMPD3 LTBP4 WNK4 FRMD3	1.24e-06	186	82	6	c116cc9f41971622264434ebe29d18e719b0ae19
ToppCell	droplet-Limb_Muscle-nan-3m-Mesenchymal-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPG2 FBN1 LAMA2 CD302 SMPD3 LTBP4	1.32e-06	188	82	6	7191087d8754f5e8700e3d744cd920ee26db1e57
ToppCell	Mesenchymal-myofibroblast_cell\|World / Lineage, Cell type, age group and donor	CACNA1C FAT1 FBN1 CCBE1 LAMA2 BCHE	1.36e-06	189	82	6	44e37f88137bb249933eb615235b2cf2ae7f3925
ToppCell	LPS_only-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNA1C FBN1 CCBE1 LTBP4 TSPAN5 FRMD3	1.36e-06	189	82	6	2a22b9fae70afb3dab8476f9c00e48a4df756410
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	JAK2 CACNA1C FBN1 PXDN LAMA2 LTBP4	1.41e-06	190	82	6	0fea33f2dc1efa23aaa2da1c318482a52a313ff1
ToppCell	droplet-Mammary_Gland-nan-21m\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPG2 BTG2 FBN1 LAMA2 CD302 LTBP4	1.45e-06	191	82	6	8022059e434fd411dc539819f969bd4f94861281
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNA1C FBN1 CCBE1 LTBP4 FRMD3 IGDCC4	1.49e-06	192	82	6	f4fc2b0121f879bab2bee99dfb5ff2c3ca1c0e1b
ToppCell	AT1_cells-Donor_02\|World / lung cells shred on cell class, cell subclass, sample id	HSPG2 ZFYVE9 PXDN CCBE1 ARHGAP45 AGRN	1.49e-06	192	82	6	0444f9e9cef7403e220e862b5a787443d3f5c9ac
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNA1C FBN1 CCBE1 LTBP4 FRMD3 IGDCC4	1.59e-06	194	82	6	89b706af2b25991fc2707eb24f49ba6ff3ae01f7
ToppCell	Bronchial-NucSeq-Stromal-Fibroblastic-Fibro_myofibroblast\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ADAMTS10 FBN1 ADAMTS7 CCBE1 LAMA2 KIF7	1.63e-06	195	82	6	f5e91ce20a7ce528dc4c1a968c7bf096bf45c528
ToppCell	Fibroblasts-DKK3+_Fibroblasts\|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	HSPG2 FAT1 FBN1 PXDN SERTAD4 LAMA2	1.79e-06	198	82	6	4f4632f26a2043c5e4ab89031b4229b5dca1bd48
ToppCell	cellseq-Mesenchymal-Fibroblastic-Fibroblastic_2\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CACNA1C FBN1 CCBE1 LAMA2 BCHE LTBP4	1.84e-06	199	82	6	66a79732caf2f04c09b4d9832377aa01ca477677
ToppCell	Control_saline-Mesenchymal_fibroblastic\|Control_saline / Treatment groups by lineage, cell group, cell type	FBN1 CCBE1 BCHE CD302 LTBP4 FRMD3	1.89e-06	200	82	6	64ae5cf6cb4fc94cf1052abd82648f6b8e6445fe
ToppCell	proximal-mesenchymal-Adventitial_Fibroblast\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	FBN1 CCBE1 LAMA2 BCHE LTBP4 IGDCC4	1.89e-06	200	82	6	58c5870030192b337e7d883044948634fcd17d2c
ToppCell	proximal-mesenchymal-Adventitial_Fibroblast-3\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	FBN1 CCBE1 LAMA2 BCHE LTBP4 IGDCC4	1.89e-06	200	82	6	05486d86868f6a93429226063cca270f00dd8714
ToppCell	proximal-3-mesenchymal-Adventitial_Fibroblast\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	FBN1 CCBE1 LAMA2 BCHE LTBP4 IGDCC4	1.89e-06	200	82	6	869d45b71efd395d050873db5fee2ed0443d5e6f
ToppCell	Control_saline-Mesenchymal_fibroblastic-Fibroblasts\|Control_saline / Treatment groups by lineage, cell group, cell type	FBN1 CCBE1 BCHE CD302 LTBP4 FRMD3	1.89e-06	200	82	6	a1fc74c1b27e104895910bc7cdce7ba33d30df7e
ToppCell	Control_saline-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|Control_saline / Treatment groups by lineage, cell group, cell type	FBN1 CCBE1 BCHE CD302 LTBP4 FRMD3	1.89e-06	200	82	6	bd8cf33502adea320e91ca2af14e1911d88ad374
ToppCell	Biopsy_Control_(H.)-Mesenchymal-PLIN2+_Fibroblasts\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	FBN1 PXDN LAMA2 BCHE IGDCC4 KIF7	1.89e-06	200	82	6	cdaf462b1db29dab61038eeab5ddd3eef3386763
ToppCell	Children_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CCBE1 LAMA2 BCHE WNK4 KIF7	9.41e-06	153	82	5	1524557514668f515ac1bbe847611f564b265b42
ToppCell	Children_(3_yrs)-Mesenchymal-chondrocyte\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CACNA1C FBN1 CCBE1 LAMA2 IGDCC3	1.07e-05	157	82	5	f147e24f2ece82e1c54750868954d09b3c461804
ToppCell	Children_(3_yrs)-Mesenchymal-chondrocyte-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CACNA1C FBN1 CCBE1 LAMA2 IGDCC3	1.10e-05	158	82	5	e5636c0b608d68bd426a2b446ac508e4512e86a4
ToppCell	droplet-Marrow-BM-30m-Lymphocytic-immature_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IFT140 FBN1 SUOX UROD CTSE	1.32e-05	164	82	5	f3772227f5aa75a3672d945f8d5bf3fa0b4e456b
ToppCell	Adult-Mesenchymal-chondrocyte-D231\|Adult / Lineage, Cell type, age group and donor	CACNA1C FBN1 CCBE1 LAMA2 LTBP4	1.32e-05	164	82	5	2ba57dce5f69a88f0d1e450b9780425e2d9ca7d4
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW23-OPC_related\|GW23 / Sample Type, Dataset, Time_group, and Cell type.	IFT140 SUOX EXO1 HSPA1L HSPA2	1.52e-05	169	82	5	29db25e7c5f31d98a08a35d7ec5ade203242bc50
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW23-OPC_related-Oligodendrocyte/OPC\|GW23 / Sample Type, Dataset, Time_group, and Cell type.	IFT140 SUOX EXO1 HSPA1L HSPA2	1.52e-05	169	82	5	b1611e61f635f8f9b87250e026ad30999cbee041
ToppCell	AT1-AT2_cells-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	PXDN CTSE AGRN TFF3 KIF7	1.66e-05	172	82	5	0be41df5d35d818deb7316ac21c9366eb4b7bfd1
ToppCell	Children_(3_yrs)-Mesenchymal-myofibroblast_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CACNA1C FBN1 CCBE1 LAMA2 BCHE	1.70e-05	173	82	5	1f16d47f5548e257e4b17f8070c5619780a9c5fd
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m-Mesenchymal-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPG2 FBN1 CD302 SMPD3 LTBP4	1.75e-05	174	82	5	68a6ed81e7e1f95b61f7ee20403980fa3a8db4d0
ToppCell	3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FBN1 CCBE1 LAMA2 BCHE LTBP4	1.80e-05	175	82	5	1799a7be623dc3bf53ba580a7c47d2619969d708
ToppCell	3'-GW_trimst-2-SmallIntestine-Epithelial-mature_enterocytic-Paneth\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TRAF1 COL11A2 RPS6KL1 PLXNB1 TFF3	1.80e-05	175	82	5	24651f95540ea2c8f3720aa943cbdd15661ee3fa
ToppCell	wk_15-18-Hematologic-Meg-ery-Primitive_erythrocyte\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	UROD CTSE TF TSPAN5 WNK4	1.85e-05	176	82	5	664a7d15563428d0ae156d97aa88415fd0a0506a
ToppCell	droplet-Lung-30m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	JAK2 TRAF1 GRIN2C HSPA1L RAB11FIP3	1.90e-05	177	82	5	4672cc75225a4a23b298afa8ce439628262519db
ToppCell	-Donor_02\|World / lung cells shred on cell class, cell subclass, sample id	CACNA1C FBN1 CCBE1 LAMA2 LTBP4	2.01e-05	179	82	5	10fadbaa1b6d21cbf9f354d717cc4c225619f4fd
ToppCell	AT1_cells-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	HSPG2 PGGHG CTSE AGRN PLXNB1	2.01e-05	179	82	5	1603117b52623663458a977c94bf7f9f6c1114b8
ToppCell	Control-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNA1C CCBE1 BCHE FRMD3 IGDCC4	2.06e-05	180	82	5	08ae0f5d95c45feba68ad99788f7af7ff4c979af
ToppCell	Children_(3_yrs)-Mesenchymal-myofibroblast_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CACNA1C FBN1 CCBE1 LAMA2 BCHE	2.06e-05	180	82	5	01f2e5d96016823482f89ba503d007d4bd88eeac
ToppCell	5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FBN1 CCBE1 LAMA2 BCHE LTBP4	2.12e-05	181	82	5	b116c68393d8836bac080f81a8fcbeb52e0403e7
ToppCell	P15-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	FBN1 LAMA2 OAT CD302 LTBP4	2.17e-05	182	82	5	e9fcae9d03a6faf85b91882c5da699037bc61aeb
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FBN1 CCBE1 LAMA2 CD302 LTBP4	2.17e-05	182	82	5	b7d532feb73167e05475855061b35a209583f44c
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FBN1 CCBE1 LAMA2 CD302 LTBP4	2.17e-05	182	82	5	af65f0fc3f9e5d9ce69ee5faaf5b6cb7f8412e0c
ToppCell	facs-Lung-EPCAM-24m-Mesenchymal-Adventitial_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN1 ADAMTS7 LAMA2 CD302 LTBP4	2.23e-05	183	82	5	63294d66e3ccf152ffe5d1237106764c14390b62
ToppCell	facs-Lung-EPCAM-24m-Mesenchymal-adventitial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN1 ADAMTS7 LAMA2 CD302 LTBP4	2.23e-05	183	82	5	7e5c467fd1b156b928f1611a12ab4affb9f714b7
ToppCell	343B-Epithelial_cells-Epithelial-I_(AT1)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	HSPG2 PGGHG CTSE AGRN FRMD3	2.29e-05	184	82	5	c7073d1b2c4fdb154d87678b92a0629c02116972
ToppCell	343B-Epithelial_cells-Epithelial-I_(AT1)\|343B / Donor, Lineage, Cell class and subclass (all cells)	PGGHG SERTAD4 CTSE AGRN FRMD3	2.29e-05	184	82	5	cb15d6bae52c5ec251c2235859dc7e65f630ae23
ToppCell	343B-Epithelial_cells-Epithelial-I_(AT1)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	HSPG2 PGGHG CTSE AGRN FRMD3	2.29e-05	184	82	5	1ed558a88215b248431c524ea16f13d9022ae98c
ToppCell	343B-Epithelial_cells-Epithelial-I_(AT1)-\|343B / Donor, Lineage, Cell class and subclass (all cells)	PGGHG SERTAD4 CTSE AGRN FRMD3	2.29e-05	184	82	5	bde4eaabd3e9bdaed23867d23a919b9d84b52d4b
ToppCell	Adult-Mesenchymal-matrix_fibroblast_2_cell-D231\|Adult / Lineage, Cell type, age group and donor	ADAMTS10 CACNA1C FBN1 LAMA2 IGDCC4	2.35e-05	185	82	5	fb6bd7e849ecf4ed9cd9c4e2a946a2d12d62f804
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	FBN1 SERTAD4 LAMA2 BCHE LTBP4	2.35e-05	185	82	5	9f19f04fc4d97dfc2dd78cde77b515f1cb5d51ec
ToppCell	P15-Mesenchymal-mesenchymal_fibroblast\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	BTG2 FBN1 OAT CD302 LTBP4	2.35e-05	185	82	5	46460e74cc613df9043f5404e7342aa13cc34873
ToppCell	wk_08-11-Hematologic-Meg-ery-Cycling_definitive_erythroblast\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	OAT UROD CTSE TF RPS6KL1	2.48e-05	187	82	5	c0965293f08d3e49000871777a5b26d81a4af203
ToppCell	P15-Mesenchymal\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	BTG2 FBN1 LAMA2 OAT CD302	2.54e-05	188	82	5	f1ba0b661621a65c91432e62ba73531bdf18e7c1
ToppCell	droplet-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HSPG2 FBN1 SERTAD4 LTBP4 IGDCC4	2.54e-05	188	82	5	6c6486cae9a8f2f8200598cb4bfd3fd513eb28a3
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-lymphatic_endothelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	HSPG2 FBN1 ADAMTS7 TSPAN5 TFF3	2.54e-05	188	82	5	26915db8863f4115b46a81982e187322e21600fd
ToppCell	10x3'2.3-week_14-16-Mesenchymal_myocytic-stroma-muscle_stem_cell\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	HSPG2 FAT1 CCBE1 LAMA2 TF	2.54e-05	188	82	5	de6f4889e0c5f39fbbaefd85526f645c6afa09d5
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	HSPG2 FBN1 ADAMTS7 TSPAN5 TFF3	2.54e-05	188	82	5	3f76c0f912f8f023ea425be7f43593b3d7f967e3
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	HSPG2 FBN1 ADAMTS7 TSPAN5 TFF3	2.54e-05	188	82	5	61ee7b152745164293d8a44ef91ee2393efbdca5
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FBN1 PXDN CCBE1 LAMA2 LTBP4	2.60e-05	189	82	5	71397e993a77d70b2eeede240bdfc7660b558987
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FBN1 PXDN CCBE1 LAMA2 LTBP4	2.60e-05	189	82	5	4eea4759520c312bd17a681034d8074e47093d2b
ToppCell	facs-Lung-18m-Mesenchymal\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FBN1 LAMA2 OAT CD302 LTBP4	2.60e-05	189	82	5	bdf8db938aa0863c4fed6fa99dcffd63c8c20c31
ToppCell	droplet-Mammary_Gland-nan-21m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPG2 FBN1 LAMA2 CD302 SMPD3	2.60e-05	189	82	5	bc54ffd7bd1627a36747a80ce5139e4a69928400
ToppCell	droplet-Limb_Muscle-nan-21m-Mesenchymal-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN1 LAMA2 CD302 SMPD3 LTBP4	2.60e-05	189	82	5	0a8b827bba1efd885ad6c06929251c741dc3a541
ToppCell	facs-Lung-18m-Mesenchymal-fibroblast\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FBN1 LAMA2 OAT CD302 LTBP4	2.60e-05	189	82	5	40cbd679dc0548bf5207e1b033c0597886ad6fe1
ToppCell	tumor_Lung-Fibroblasts-Mesothelial_cells\|Fibroblasts / Location, Cell class and cell subclass	BCHE SMPD3 CTSE AGRN WNK4	2.67e-05	190	82	5	d82ab67735c1f365d4b0e02b5fa91c64cdc234da
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNA1C CCBE1 TSPAN5 FRMD3 IGDCC4	2.67e-05	190	82	5	45df8fee00f8949937863159d7aa042e72748d9b
ToppCell	droplet-Mammary_Gland-nan-21m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPG2 FBN1 LAMA2 CD302 SMPD3	2.67e-05	190	82	5	f3ca94a31a35eed5fecf3c4b8c957e1bc4150158
ToppCell	droplet-Mammary_Gland-nan-21m-Mesenchymal\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPG2 FBN1 LAMA2 CD302 SMPD3	2.67e-05	190	82	5	c2cd1eb674162ee40502c3380b7245c85079c7ce
ToppCell	droplet-Mammary_Gland-nan-18m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPG2 FBN1 LAMA2 CD302 SMPD3	2.67e-05	190	82	5	47077579496c5340e99f61499427a3a36b566da3
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FBN1 PXDN CCBE1 LAMA2 LTBP4	2.74e-05	191	82	5	a58c75e9580139fb370b498d95660f10f3a2a27b
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNA1C FBN1 CCBE1 LTBP4 IGDCC4	2.74e-05	191	82	5	b13229bb7f3713a392271aaf5dbae3edd1b9fe5a
ToppCell	facs-Lung-24m-Mesenchymal-fibroblast\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FBN1 LAMA2 OAT CD302 LTBP4	2.74e-05	191	82	5	094c9d3270fc1e487ccf10fb4936af5f081f6009
ToppCell	facs-Lung-24m-Mesenchymal\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FBN1 LAMA2 OAT CD302 LTBP4	2.74e-05	191	82	5	ba02cbdfda6a94374a6472eb88499059979af472
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FBN1 PXDN CCBE1 LAMA2 LTBP4	2.74e-05	191	82	5	39092a0aff8097617820c59f5fea9ee2bb4f63a2
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FBN1 PXDN CCBE1 LAMA2 LTBP4	2.74e-05	191	82	5	ee5f1b1c59029c46cbb1a00935c03b9317bb9da9
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FBN1 PXDN CCBE1 LAMA2 LTBP4	2.81e-05	192	82	5	9093a9e94a25682d109a7f6edc256a25a61103a0
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	FBN1 LAMA2 BCHE LTBP4 IGDCC4	2.81e-05	192	82	5	8d56e360ebc624ca4cd7f0af4f3cc599c244f134
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Macroglial-astrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA4B LAMA2 GRIN2C PLXNB1 IGDCC4	2.81e-05	192	82	5	261211a86e6f63b09c2ddce1d2d9257d311f1770
ToppCell	facs-Pancreas-Exocrine-3m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPG2 FBN1 LAMA2 CD302 LTBP4	2.81e-05	192	82	5	8937a59f6bbe07f671bdabbd3707dc9c17a14cd9
ToppCell	droplet-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HSPG2 FBN1 LAMA2 CD302 LTBP4	2.81e-05	192	82	5	0e7e55505bd5454d7cf952a63fdcb46ec76f1973
ToppCell	PND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	HSPG2 FBN1 LAMA2 CD302 LTBP4	2.81e-05	192	82	5	29bee88b45e23f16543ffc7cc361bc5da5d16a2b
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FBN1 PXDN CCBE1 LAMA2 LTBP4	2.81e-05	192	82	5	9ed5d49621ec1aa01716dc369bba1450b5f015f5
ToppCell	facs-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HSPG2 FBN1 LAMA2 CD302 LTBP4	2.81e-05	192	82	5	7b48df661f61ce494bf6f0b9a74b0422e29c24bf
ToppCell	facs-Pancreas-Exocrine-3m-Mesenchymal\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPG2 FBN1 LAMA2 CD302 LTBP4	2.81e-05	192	82	5	e4a7f2673f801b008ca67291db2fb2b9fd2955b8
ToppCell	LPS_only-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNA1C FBN1 CCBE1 LTBP4 IGDCC4	2.81e-05	192	82	5	df1545670370fb1010c567cd059c2783eab315f7
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNA1C FBN1 CCBE1 LTBP4 IGDCC4	2.81e-05	192	82	5	dcd924d6eb67d33ee9f5d3e8ab6e1d4283d6b708
ToppCell	facs-Pancreas-Exocrine-3m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPG2 FBN1 LAMA2 CD302 LTBP4	2.81e-05	192	82	5	ac1477433704573f95111eee6263b93668d2845e
ToppCell	facs-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HSPG2 FBN1 LAMA2 CD302 LTBP4	2.81e-05	192	82	5	32acd89617934016cd135d2cc797e8e79ae1b37f
ToppCell	PND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	HSPG2 FBN1 LAMA2 CD302 LTBP4	2.81e-05	192	82	5	cdc652dbfabe41b324fd85c1ed933d29fb73a49f
ToppCell	Adult-Mesenchymal-matrix_fibroblast_2_cell\|Adult / Lineage, Cell type, age group and donor	ADAMTS10 FBN1 LAMA2 IGDCC4 KIF7	2.81e-05	192	82	5	d21f0f577156f17c899b08871046a26b88aea011
ToppCell	Mesenchymal-matrix_fibroblast_2_cell\|World / Lineage, Cell type, age group and donor	FBN1 LAMA2 BCHE LTBP4 IGDCC4	2.81e-05	192	82	5	a769158c49d2b208c4224d85e7ae68c85cc372ed
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNA1C FBN1 CCBE1 LTBP4 IGDCC4	2.81e-05	192	82	5	deeecd26972241846b4cb998edf0c7a87ff0c4df
ToppCell	facs-Lung-EPCAM-18m-Mesenchymal\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN1 LAMA2 OAT CD302 LTBP4	2.81e-05	192	82	5	5876ff75e273a48e7ad8236423fb41e4ae4c0a91
ToppCell	facs-Lung-nan-3m-Mesenchymal\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPG2 FBN1 LAMA2 CD302 LTBP4	2.88e-05	193	82	5	d9c20a092b507c43fcf7ccb04073fecd27d1749c
ToppCell	droplet-Limb_Muscle-nan-3m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPG2 FBN1 LAMA2 CD302 LTBP4	2.88e-05	193	82	5	428b1a3ad87dff7f65de5161d40f102572a9341b
ToppCell	10x3'2.3-week_12-13-Hematopoietic-erythroid-mid_erythroid\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	OAT UROD CTSE TF TSPAN5	2.88e-05	193	82	5	1e19f80c52833fb21a8d597a3ba2c4ff464c4559
ToppCell	facs-Lung-24m-Mesenchymal-fibroblast-adventitial_fibroblast\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HSPG2 FBN1 LAMA2 CD302 LTBP4	2.88e-05	193	82	5	e27885a9e1a2a3e165c5366d4cfcda05c5454483
ToppCell	droplet-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HSPG2 FBN1 LAMA2 CD302 LTBP4	2.88e-05	193	82	5	025836c5c5a711e477c326559e618e47cae42d11
Drug	Emetine dihydrochloride [316-42-7]; Down 200; 7.2uM; PC3; HT_HG-U133A	HSPG2 PDZD8 CD302 PLXNB1 DDX3X TBCD DNPEP	4.42e-06	183	82	7	4243_DN
Drug	Sulfamerazine [127-79-7]; Up 200; 15.2uM; HL60; HT_HG-U133A	WSCD1 ZFYVE9 PGGHG RTEL1 UROD HSPA2 PYCR3	7.17e-06	197	82	7	2181_UP
Drug	ferrioxamine	SIGLEC1 UROD TF	7.28e-06	11	82	3	CID000441292
Drug	sulfate	MAG JAK2 CACNA1C HSPG2 IGF2R SUOX LAMA2 BCHE OAT SIGLEC1 AKR1A1 GRIN2C UROD TF AGRN TFF3	1.26e-05	1292	82	16	CID000001117
Disease	Weill-Marchesani syndrome	ADAMTS10 FBN1	2.28e-05	3	82	2	C0265313
Disease	Weill-Marchesani Syndrome, Autosomal Dominant	ADAMTS10 FBN1	2.28e-05	3	82	2	C1869115
Disease	Weill-Marchesani Syndrome, Autosomal Recessive	ADAMTS10 FBN1	2.28e-05	3	82	2	C1869114
Disease	Weill-Marchesani syndrome (implicated_via_orthology)	ADAMTS10 FBN1	2.28e-05	3	82	2	DOID:0050475 (implicated_via_orthology)
Disease	Weill-Marchesani syndrome	ADAMTS10 FBN1	4.56e-05	4	82	2	cv:C0265313
Disease	Weill-Marchesani syndrome (is_implicated_in)	ADAMTS10 FBN1	4.56e-05	4	82	2	DOID:0050475 (is_implicated_in)
Disease	Disproportionate short stature	HSPG2 IFT140 COL11A2 FBN1	6.42e-05	77	82	4	C0878659
Disease	type 1 diabetes mellitus (is_implicated_in)	IGF2R PTPRN2 BCHE TF	9.45e-05	85	82	4	DOID:9744 (is_implicated_in)
Disease	butyrylcholinesterase measurement	RNPEP BCHE	1.14e-04	6	82	2	EFO_0004571
Disease	Hypermetropia	PTPRN2 LAMA2 GRIN2C AGRN	1.99e-04	103	82	4	HP_0000540
Disease	Muscular Dystrophy	LAMA2 BCHE	2.11e-04	8	82	2	C0026850
Disease	2-hydroxystearate measurement	MUC19 STK24	2.71e-04	9	82	2	EFO_0021059
Disease	Optic Atrophy	ATAD3A TBCD	3.38e-04	10	82	2	C0029124
Disease	gastric adenocarcinoma (is_implicated_in)	KMT2D RTEL1	4.13e-04	11	82	2	DOID:3717 (is_implicated_in)
Disease	placenta growth factor measurement	RPS6KL1 WNK4	4.13e-04	11	82	2	EFO_0010626
Disease	colon carcinoma (is_marker_for)	KMT2D IGF2R	5.83e-04	13	82	2	DOID:1520 (is_marker_for)
Disease	inherited metabolic disorder (is_implicated_in)	SUOX BCHE	7.82e-04	15	82	2	DOID:655 (is_implicated_in)
Disease	T-Cell Lymphoma	KMT2D DDX3X	8.93e-04	16	82	2	C0079772
Disease	Necrotizing Enterocolitis	OAT AKR1A1	1.01e-03	17	82	2	C0520459
Disease	Limb Deformities, Congenital	CACNA1C COL11A2	1.01e-03	17	82	2	C0206762
Disease	esophagus squamous cell carcinoma (is_marker_for)	JAK2 FAT1 KMT2D	1.16e-03	74	82	3	DOID:3748 (is_marker_for)
Disease	osteochondrodysplasia (is_implicated_in)	HSPG2 COL11A2	1.27e-03	19	82	2	DOID:2256 (is_implicated_in)
Disease	renovascular hypertension (biomarker_via_orthology)	HDAC8 LAMA2	1.27e-03	19	82	2	DOID:1591 (biomarker_via_orthology)
Disease	Liver Cirrhosis, Experimental	JAK2 FAT1 FBN1 IGF2R PXDN OAT ECT2 CTSE	1.40e-03	774	82	8	C0023893
Disease	Glioblastoma	FAT1 BCHE LTBP4	1.40e-03	79	82	3	C0017636
Disease	Giant Cell Glioblastoma	FAT1 BCHE LTBP4	1.68e-03	84	82	3	C0334588
Disease	Lewy Body Disease	MAG IGF2R	1.70e-03	22	82	2	C0752347
Disease	breast cancer (is_marker_for)	KMT2D BTG2 AKR1A1 UROD	1.79e-03	185	82	4	DOID:1612 (is_marker_for)
Disease	Cancer of Head	FAT1 UROD	2.02e-03	24	82	2	C0751177
Disease	Head Neoplasms	FAT1 UROD	2.02e-03	24	82	2	C0018675
Disease	Upper Aerodigestive Tract Neoplasms	FAT1 UROD	2.02e-03	24	82	2	C0887900
Disease	ovarian carcinoma	WSCD1 PTPRN2 SMPD3 HNRNPLL LRRC47	2.03e-03	321	82	5	EFO_0001075
Disease	Neck Neoplasms	FAT1 UROD	2.20e-03	25	82	2	C0027533
Disease	Cancer of Neck	FAT1 UROD	2.20e-03	25	82	2	C0746787
Disease	cerebellum cortex volume change measurement, age at assessment	STK24 TFF3	2.37e-03	26	82	2	EFO_0008007, EFO_0021497
Disease	Lewy body dementia, Lewy body dementia measurement	GARNL3 FRMD3	2.37e-03	26	82	2	EFO_0006792, EFO_0006799
Disease	Agouti-related protein measurement	SMPD3 TANGO6	2.56e-03	27	82	2	EFO_0008016
Disease	Acute Confusional Senile Dementia	IGF2R BCHE TF	2.68e-03	99	82	3	C0546126
Disease	Alzheimer's Disease, Focal Onset	IGF2R BCHE TF	2.68e-03	99	82	3	C0750900
Disease	Alzheimer Disease, Early Onset	IGF2R BCHE TF	2.68e-03	99	82	3	C0750901
Disease	Presenile dementia	IGF2R BCHE TF	2.68e-03	99	82	3	C0011265
Disease	Alzheimer Disease, Late Onset	IGF2R BCHE TF	2.68e-03	99	82	3	C0494463
Disease	lung small cell carcinoma (is_implicated_in)	FAT1 KMT2D	2.75e-03	28	82	2	DOID:5409 (is_implicated_in)
Disease	Familial Alzheimer Disease (FAD)	IGF2R BCHE TF	2.76e-03	100	82	3	C0276496

Protein segments in the cluster

Peptide	Gene	Start	Entry
ALGDVVGDYNFICPA	BCHE	416	P06276
AEPCLIDAAKEEYNG	RNPEP	251	Q9H4A4
CLADTQPAVLGGAYD	DNPEP	251	Q9ULA0
AVVALEDDPEFNAGC	ASRGL1	51	Q7L266
EQVPAGECCALQEYE	ATAD3A	131	Q9NVI7
SPYNEDCVLVVGEEN	CD302	211	Q8IX05
ARQAPVCGDDGVTYE	AGRN	351	O00468
TVAPGQAYDADEQCR	ADAMTS10	466	Q9H324
DAVVDGTPCYQVRAS	ADAMTS7	646	Q9UKP4
DVQESDAGPYRCVAT	IGDCC4	201	Q8TDY8
DPEASVCIYAAQVQD	MROH7	1251	Q68CQ1
QVSPADSGEYVCRVE	HSPG2	2106	P98160
YGGVASAQDEEPLAC	RAB11FIP3	276	O75154
IFDVVYEVDGCPANL	ECT2	651	Q9H8V3
CRYDPLQDNTGEVVA	JAK2	866	O60674
ECVTFAADEPVYIAG	HNRNPLL	126	Q8WVV9
GDPGADATAAYQELC	PTPRN2	656	Q92932
EKYDDIPVEATGNNC	DDX3X	161	O00571
DPCALYASEEEIGQL	UROD	306	P06132
PAYAIVTVDDCDQGA	FAT1	271	Q14517
EAVVYPLQEAAADGC	ARHGAP45	1006	Q92619
GPEDEAIYQCVAENS	IGDCC3	391	Q8IVU1
TPAEDGVYACLAENA	MAG	296	P20916
CNPGYVGIRCEQDID	EYS	721	Q5T1H1
CEDYGGDVQAVPVSA	MTIF2	311	P46199
QCASPEYAQGEDVLD	LRRTM1	341	Q86UE6
ASCDIVVDVGGEYDP	MYG1	86	Q9HB07
ENYPCLVDADGDVIS	LRRC47	446	Q8N1G4
DVYANVCGVVEGLSP	EDAR	331	Q9UNE0
IGAAPVDGEYAVECA	CTSE	301	P14091
INPDEAVAYGAAVQA	HSPA2	366	P54652
VTVAGVPCAVDAQEY	PLXNB1	1106	O43157
PNAVGKSYEVCEDGI	MUC19	631	Q7Z5P9
CFYNDVIPAGGVIED	MUC19	1606	Q7Z5P9
CPEELAFEAEVEYNG	PDZD8	186	Q8NEN9
VPGVQAAYESCEQKE	COL11A2	211	P13942
ALAGALVCAYDPEAA	DCD	11	P81605
LAEDAGQEAVYQACV	KIF7	61	Q2M1P5
NPDEAVAYGAAVQAA	HSPA1L	366	P34931
YPTDGSIAAAVEVCQ	LAMA2	711	P24043
ADSGLEVCPEDIYGV	PGGHG	351	Q32M88
ANPEELVAFDVVCGD	SMPD3	496	Q9NY59
DILAEYVPNSCDGET	PPP1R3A	171	Q16821
LGACIVQAELGDYDP	FRMD3	151	A2A2Y4
KTCYNQEGIADVPAE	CACNA1C	296	Q13936
GYEVAPDGRTCVDIN	FBN1	1961	P35555
VLGQCIPEDYDVCAE	CCBE1	81	Q6UXH8
EDPNCAGIEGVLESY	CPNE9	376	Q8IYJ1
VDECQEYGPEICGAQ	LTBP4	1006	Q8N2S1
NPDEAVAYGAAVQAA	HSPA6	366	P17066
DCPATEGIFDYAAAI	HDAC8	101	Q9BY41
LADVYAGVDVQAAIC	SEC24B	1006	O95487
GSVDIYLEQGECVPD	IFT140	41	Q96RY7
GPAEESDNLICVAYR	GARNL3	661	Q5VVW2
PVDCQVTDLAGNEYD	IGF2R	1081	P11717
NAAAAAGDPIACYTD	RTEL1	91	Q9NZ71
GAIYLAEEACPGISD	STK24	406	Q9Y6E0
LVASYCPEVVEDGVA	SEMA4B	666	Q9NPR2
CEPIVSEGAAEIAGY	SERTAD4	11	Q9NUC0
AARSQGVDCLVAPYE	EXO1	136	Q9UQ84
GVDCLVAPYEADAQL	EXO1	141	Q9UQ84
GGLYPVSAVLCDDDI	OAT	296	P04181
LEACGRCEEVPEAYV	PYCR3	156	Q53H96
DGSICVLYEEAPLAA	BTG2	116	P78543
CAAIYGNEPEIGEAL	AKR1A1	46	P14550
AEEYVGLSANQCAVP	TFF3	21	Q07654
NCEDTPEAGYFAIAV	TF	436	P02787
DIEYFCQAVGEAPSE	PPAN	386	Q9NQ55
AESGNAQAAAICEYP	PXDN	211	Q92626
INDVGPADAGRYECV	PXDN	581	Q92626
GAVVQDVVCFDAAPD	TANGO6	176	Q9C0B7
QAAVEVAGDLEVDCY	TRAF1	151	Q13077
DEGYCQAQAPVAAVL	TBC1D10B	441	Q4KMP7
EVEPQCCGEAVDNLY	RPS6KL1	436	Q9Y6S9
CCGEAVDNLYSAPEV	RPS6KL1	441	Q9Y6S9
LQVQDVPAGDDTYVC	SIGLEC1	1411	Q9BZZ2
PAEDVINTQCGYDAR	TSPAN5	191	P62079
YAGDVSQVPELGDLC	ZNF16	96	P17020
PDEAVCGENVSQIYC	TBCD	836	Q9BTW9
IVCKAVDDGYNVQPD	SUOX	506	P51687
GQDPEAQRLAEYCEV	WSCD1	316	Q658N2
EVNGAPACAQKLYAE	TTL	331	Q8NG68
GLVCEADYQPVARAV	WNK4	496	Q96J92
CLVPNEVRADENEGY	ZFYVE9	361	O95405
AAYLEEARCAVCEGP	KMT2D	221	O14686
PIYREACQEGEQAGA	GRIN2C	1126	Q14957