Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontranscription coregulator activity

MYT1L ATF7IP2 DYRK1A PEX14 RERE NCOA4 TDP2 EP300 MED13

1.83e-04562729GO:0003712
GeneOntologyMolecularFunctionprotein-macromolecule adaptor activity

MYT1L NDC1 SYNE2 ATF7IP2 FBXO7 DYRK1A PEX14 RERE GOLGA5 NCOA4 TDP2 EP300 MED13

2.31e-0411607213GO:0030674
GeneOntologyMolecularFunctiontau protein binding

DYRK1A EP300 SMAD2

6.11e-0446723GO:0048156
GeneOntologyMolecularFunctionprotein phosphatase inhibitor activity

PPP1R2 PPP1R2B PPP1R2P1

7.80e-0450723GO:0004864
GeneOntologyMolecularFunctiontranscription coactivator activity

MYT1L DYRK1A RERE NCOA4 EP300 MED13

7.84e-04303726GO:0003713
GeneOntologyMolecularFunctionco-SMAD binding

USP9Y SMAD2

8.27e-0412722GO:0070410
GeneOntologyMolecularFunctionphosphatase inhibitor activity

PPP1R2 PPP1R2B PPP1R2P1

9.77e-0454723GO:0019212
GeneOntologyMolecularFunctionmolecular adaptor activity

MYT1L NDC1 SYNE2 ATF7IP2 FBXO7 DYRK1A PEX14 RERE GOLGA5 NCOA4 TDP2 EP300 MED13

1.01e-0313567213GO:0060090
GeneOntologyCellularComponentnuclear protein-containing complex

NDC1 KANSL1 EP400 ARID2 SYNE2 BACH1 NXF2 REL RERE PRDM4 SAP130 MED13 PHC1 SMAD2

1.37e-0413776914GO:0140513
HumanPhenoPosteriorly rotated ears

NALCN ARID2 DDR2 PEX14 RERE HUWE1 CPLANE1 EP300 PPM1B SMAD2

1.54e-054702310HP:0000358
HumanPhenoNasogastric tube feeding in infancy

KANSL1 NALCN DYRK1A EP300

1.89e-0537234HP:0011470
HumanPhenoAbnormality of the palpebral fissures

MYT1L KANSL1 NALCN ARID2 DDR2 DYRK1A PEX14 RERE HUWE1 EP300 MED13 PHC1 SMAD2

2.33e-058802313HP:0008050
HumanPhenoPectus excavatum

KANSL1 ARID2 SYNE2 DDR2 DYRK1A HUWE1 EP300 SMAD2

5.07e-05323238HP:0000767
HumanPhenoAbnormal meningeal morphology

KANSL1 ARID2 DDR2 PEX14 XIAP CPLANE1 EP300 SMAD2

5.18e-05324238HP:0010651
HumanPhenoAbnormal sternum morphology

KANSL1 NALCN ARID2 SYNE2 DDR2 DYRK1A HUWE1 EP300 SMAD2

1.21e-04474239HP:0000766
HumanPhenoAbnormal nasal bridge morphology

MYT1L KANSL1 NALCN ARID2 DDR2 DYRK1A PEX14 RERE HUWE1 CPLANE1 EP300 MED13 PPM1B

1.30e-0410292313HP:0000422
HumanPhenoFrontal bossing

KANSL1 NALCN ARID2 DDR2 PEX14 RERE HUWE1 CPLANE1 EP300 PPM1B SMAD2

1.40e-047382311HP:0002007
HumanPhenoAbnormal shape of the frontal region

KANSL1 NALCN ARID2 DDR2 PEX14 RERE HUWE1 CPLANE1 EP300 PPM1B SMAD2

1.45e-047412311HP:0011218
HumanPhenoAbnormal frontal bone morphology

KANSL1 NALCN ARID2 DDR2 PEX14 RERE HUWE1 CPLANE1 EP300 PPM1B SMAD2

1.47e-047422311HP:0430000
HumanPhenoAbnormal eyelid morphology

MYT1L KANSL1 NALCN ARID2 DDR2 DYRK1A PEX14 RERE HUWE1 CPLANE1 EP300 MED13 PHC1 PPM1B SMAD2

1.83e-0414082315HP:0000492
HumanPhenoShort 5th toe

DYRK1A EP300

1.93e-045232HP:0011917
HumanPhenoHappy demeanor

KANSL1 NALCN DYRK1A

1.95e-0426233HP:0040082
HumanPhenoBlepharophimosis

KANSL1 DDR2 RERE HUWE1 EP300

2.25e-04129235HP:0000581
HumanPhenoCryptorchidism

MYT1L KANSL1 NALCN ARID2 DYRK1A PEX14 RERE HUWE1 USP9Y CPLANE1 EP300

2.33e-047802311HP:0000028
HumanPhenoAbnormal size of the palpebral fissures

KANSL1 ARID2 DDR2 RERE HUWE1 EP300 MED13

2.37e-04298237HP:0200007
HumanPhenoAbnormal location of ears

KANSL1 NALCN ARID2 DDR2 DYRK1A PEX14 RERE HUWE1 CPLANE1 EP300 PPM1B SMAD2

2.79e-049452312HP:0000357
HumanPhenoEnlarged naris

NALCN DDR2

2.89e-046232HP:0009931
HumanPhenoAbnormal testis morphology

MYT1L KANSL1 NALCN ARID2 DYRK1A PEX14 RERE HUWE1 AGBL5 USP9Y CPLANE1 EP300 SMAD2

3.50e-0411292313HP:0000035
HumanPhenoNon-obstructive azoospermia

MYT1L KANSL1 NALCN ARID2 DYRK1A PEX14 RERE HUWE1 AGBL5 USP9Y CPLANE1 EP300 SMAD2

3.60e-0411322313HP:0011961
HumanPhenoAbnormality of calvarial morphology

KANSL1 NALCN ARID2 DDR2 DYRK1A PEX14 RERE HUWE1 CPLANE1 TDP2 EP300 PPM1B SMAD2

3.66e-0411342313HP:0002648
HumanPhenoAbnormal upper lip morphology

MYT1L KANSL1 NALCN ARID2 DDR2 DYRK1A RERE HUWE1 CPLANE1 EP300 MED13 PHC1

3.98e-049802312HP:0000177
HumanPhenoConspicuously happy disposition

KANSL1 NALCN

4.04e-047232HP:0100024
HumanPhenoAzoospermia

MYT1L KANSL1 NALCN ARID2 DYRK1A PEX14 RERE HUWE1 AGBL5 USP9Y CPLANE1 EP300 SMAD2

4.52e-0411572313HP:0000027
HumanPhenoUpslanted palpebral fissure

KANSL1 DYRK1A PEX14 RERE HUWE1 EP300 PHC1

4.71e-04333237HP:0000582
HumanPhenoThin upper lip vermilion

NALCN ARID2 DYRK1A HUWE1 EP300 MED13 PHC1

5.25e-04339237HP:0000219
HumanPhenoThin lips

NALCN ARID2 DYRK1A HUWE1 EP300 MED13 PHC1

5.25e-04339237HP:0000213
HumanPhenoAbnormal spermatogenesis

MYT1L KANSL1 NALCN ARID2 DYRK1A PEX14 RERE HUWE1 AGBL5 USP9Y CPLANE1 EP300 SMAD2

6.06e-0411902313HP:0008669
HumanPhenoAbnormality of upper lip vermillion

MYT1L NALCN ARID2 DYRK1A HUWE1 EP300 MED13 PHC1

6.38e-04464238HP:0011339
HumanPhenoAbnormality of the forehead

KANSL1 NALCN ARID2 DDR2 DYRK1A PEX14 RERE HUWE1 CPLANE1 EP300 PHC1 PPM1B SMAD2

7.07e-0412082313HP:0000290
HumanPhenoAbnormal cranial suture/fontanelle morphology

KANSL1 ARID2 DDR2 PEX14 RERE HUWE1 EP300 SMAD2

7.16e-04472238HP:0000235
HumanPhenoSlanting of the palpebral fissure

KANSL1 NALCN ARID2 DYRK1A PEX14 RERE HUWE1 EP300 PHC1 SMAD2

7.40e-047392310HP:0200006
HumanPhenoLong face

KANSL1 DDR2 DYRK1A HUWE1 CPLANE1 SMAD2

7.91e-04259236HP:0000276
HumanPhenoEpicanthus

KANSL1 NALCN ARID2 DDR2 PEX14 RERE HUWE1 CPLANE1 EP300

8.64e-04614239HP:0000286
HumanPhenoJuvenile aseptic necrosis

DYRK1A EP300 SMAD2

8.82e-0443233HP:0100323
HumanPhenoDeeply set eye

MYT1L NALCN DYRK1A RERE HUWE1 EP300

9.10e-04266236HP:0000490
HumanPhenoAbnormal demeanor

KANSL1 NALCN DYRK1A

9.44e-0444233HP:5200261
HumanPhenoAbnormal male internal genitalia morphology

MYT1L KANSL1 NALCN ARID2 DYRK1A PEX14 RERE HUWE1 AGBL5 USP9Y CPLANE1 EP300 SMAD2

9.47e-0412432313HP:0000022
HumanPhenoAbnormal external nose morphology

MYT1L KANSL1 NALCN ARID2 DDR2 DYRK1A PEX14 RERE HUWE1 CPLANE1 EP300

9.81e-049162311HP:0010938
HumanPhenoHypospadias

KANSL1 ARID2 DYRK1A PEX14 RERE HUWE1 EP300

9.96e-04377237HP:0000047
HumanPhenoAbnormal calvaria morphology

KANSL1 NALCN ARID2 DDR2 DYRK1A PEX14 RERE HUWE1 CPLANE1 TDP2 EP300 PPM1B SMAD2

1.04e-0312542313HP:0002683
HumanPhenoBroad chin

KANSL1 DYRK1A

1.05e-0311232HP:0011822
HumanPhenoPyloric stenosis

KANSL1 DYRK1A PEX14 RERE

1.08e-03104234HP:0002021
HumanPhenoUnderdeveloped nasal alae

KANSL1 NALCN DDR2 DYRK1A

1.08e-03104234HP:0000430
HumanPhenoAbnormal nasal tip morphology

MYT1L KANSL1 ARID2 DYRK1A RERE HUWE1 CPLANE1

1.15e-03386237HP:0000436
HumanPhenoAbnormal morphology of the nasal alae

KANSL1 NALCN ARID2 DDR2 DYRK1A PEX14 RERE HUWE1 CPLANE1

1.16e-03639239HP:0000429
HumanPhenoFunctional abnormality of male internal genitalia

MYT1L KANSL1 NALCN ARID2 DYRK1A PEX14 RERE HUWE1 AGBL5 USP9Y CPLANE1 EP300 SMAD2

1.17e-0312692313HP:0000025
HumanPhenoSmooth philtrum

NALCN DYRK1A RERE EP300 MED13

1.18e-03185235HP:0000319
HumanPhenoAbnormality of cranial sutures

KANSL1 ARID2 PEX14 RERE HUWE1 EP300 SMAD2

1.18e-03388237HP:0011329
HumanPhenoMotor stereotypy

MYT1L ARID2 DYRK1A RERE HUWE1 EP300

1.19e-03280236HP:0000733
HumanPhenoAbnormality of the pylorus

KANSL1 DYRK1A PEX14 RERE

1.20e-03107234HP:0004400
MousePhenoventricular septal defect

CCP110 HEG1 XIRP2 ARID2 RERE CPLANE1 HECTD1 EP300 PHC1

1.15e-06261589MP:0010402
MousePhenoembryonic lethality during organogenesis

PPP1R2 PPP1R2B HEG1 EP400 ARID2 MTERF3 DYRK1A PPP1R2P1 XIAP RERE HUWE1 TACC3 EP300 SMAD2

9.86e-068765814MP:0006207
MousePhenoabnormal interventricular septum morphology

CCP110 HEG1 XIRP2 ARID2 RERE CPLANE1 HECTD1 EP300 PHC1

1.05e-05342589MP:0000281
MousePhenoembryonic lethality during organogenesis, complete penetrance

PPP1R2 PPP1R2B EP400 ARID2 MTERF3 PPP1R2P1 XIAP RERE HUWE1 TACC3 EP300 SMAD2

2.41e-057005812MP:0011098
MousePhenoabnormal heart septum morphology

CCP110 HEG1 XIRP2 ARID2 RERE CPLANE1 HECTD1 EP300 PHC1

2.85e-05388589MP:0006113
MousePhenosmall heart

CSHL1 XIRP2 DDR2 DYRK1A HUWE1 ZNF236 SAP130 EP300

5.00e-05321588MP:0002188
MousePhenoabnormal heart valve morphology

ARID2 CPLANE1 HECTD1 SAP130 EP300 PHC1

5.62e-05163586MP:0000285
MousePhenoabnormal heart and great artery attachment

CCP110 ARID2 RERE CPLANE1 HECTD1 PHC1

1.98e-04205586MP:0010426
MousePhenoabnormal heart and great vessel attachment

CCP110 ARID2 RERE CPLANE1 HECTD1 PHC1

2.15e-04208586MP:0010425
MousePhenonon-midline cleft palate

CPLANE1 PHC1

3.51e-047582MP:0021209
MousePhenobilateral cleft palate

CPLANE1 PHC1

3.51e-047582MP:0021210
MousePhenoabnormal heart ventricle morphology

CCP110 HEG1 XIRP2 ARID2 RERE CPLANE1 PRDM4 HECTD1 SAP130 EP300 PHC1

3.58e-047935811MP:0005294
DomainUBA-like

N4BP2 NXF2 HUWE1 TDP2

9.70e-0564704IPR009060
DomainARM-type_fold

MON2 USO1 ARID2 HUWE1 USP9Y HECTD1

1.69e-03339706IPR016024
DomainCH

LRCH2 SYNE2 NAV2

1.86e-0365703SM00033
DomainCH

LRCH2 SYNE2 NAV2

2.31e-0370703PF00307
Domain-

LRCH2 SYNE2 NAV2

2.40e-03717031.10.418.10
DomainCH

LRCH2 SYNE2 NAV2

2.60e-0373703PS50021
DomainCH-domain

LRCH2 SYNE2 NAV2

2.81e-0375703IPR001715
DomainARM-like

MON2 ARID2 HUWE1 USP9Y HECTD1

3.43e-03270705IPR011989
DomainHECT

HUWE1 HECTD1

4.57e-0327702PF00632
DomainHECTc

HUWE1 HECTD1

4.57e-0327702SM00119
DomainHECT_dom

HUWE1 HECTD1

4.57e-0327702IPR000569
DomainIPT

EBF2 REL

4.57e-0327702SM00429
DomainHECT

HUWE1 HECTD1

4.57e-0327702PS50237
DomainTIG

EBF2 REL

6.00e-0331702PF01833
DomainSNF2_N

EP400 CHD9

6.39e-0332702IPR000330
DomainIPT

EBF2 REL

6.39e-0332702IPR002909
DomainSNF2_N

EP400 CHD9

6.39e-0332702PF00176
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

PPP1R2 MON2 CCP110 EP400 USO1 N4BP2 RNF213 QSER1 HUWE1 GOLGA5 NCOA4 HECTD1 ERBIN

3.30e-09733721334672954
Pubmed

Structural basis for regulation of protein phosphatase 1 by inhibitor-2.

PPP1R2 PPP1R2B PPP1R2P1

8.51e-09372317636256
Pubmed

Interactomes of Glycogen Synthase Kinase-3 Isoforms.

PPP1R2 CCP110 LRCH2 USO1 PFAS AKAP11 HECTD1 ERBIN

1.28e-0820972836779422
Pubmed

Cloning and characterization of human phosphatase inhibitor-2 (IPP-2) sequences.

PPP1R2 PPP1R2B PPP1R2P1

3.40e-0847237949733
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

MYT1L MIA2 NECAB1 BACH1 FBXO7 DYRK1A CHD9 HUWE1 USP9Y PRDM4 HECTD1 TDP2 EP300 MED13 SMAD2

4.81e-081285721535914814
Pubmed

Regulators of the protein phosphatase PP1γ2, PPP1R2, PPP1R7, and PPP1R11 are involved in epididymal sperm maturation.

PPP1R2 PPP1R2B PPP1R2P1

8.48e-08572330144392
Pubmed

Protein Phosphatase-1 Inhibitor-2 Is a Novel Memory Suppressor.

PPP1R2 PPP1R2B PPP1R2P1

8.48e-08572326558779
Pubmed

Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.

KANSL1 ARID2 WBP1L PEX14 SCAF11 RERE HECTD1 ERBIN MED13 PPM1B

1.58e-07536721015840001
Pubmed

Exchangeable gene trap using the Cre/mutated lox system.

KANSL1 ARID2 WBP1L PEX14 SCAF11 RERE HECTD1 ERBIN MED13 PPM1B

1.64e-07538721010512203
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

CCP110 USO1 N4BP2 SYNE2 BACH1 DYRK1A NAV2 XIAP AKAP11 INPP5F HECTD1 ERBIN

1.93e-07861721236931259
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

USO1 N4BP2 ATF7IP2 RERE HUWE1 INPP5F TACC3 GOLGA5 PHC1

2.09e-0741872934709266
Pubmed

Inhibitor-2 prevents protein phosphatase 1-induced cardiac hypertrophy and mortality.

PPP1R2 PPP1R2B PPP1R2P1

2.96e-07772318689497
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

MON2 PCNX2 HEG1 KANSL1 EP400 DYRK1A NAV2 PFAS HUWE1 ZNF236 HECTD1 EP300 MED13

3.91e-071105721335748872
Pubmed

Primary cilia are WNT-transducing organelles whose biogenesis is controlled by a WNT-PP1 axis.

PPP1R2 PPP1R2B PPP1R2P1

4.73e-07872336693320
Pubmed

The protein interaction landscape of the human CMGC kinase group.

PPP1R2 CCP110 EP400 BACH1 DYRK1A AKAP11 HUWE1 TDP2 EP300 MED13

1.67e-06695721023602568
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

PCNX2 RNF213 PEX14 XIAP CHD9 SCAF11 RERE QSER1 HUWE1 ZNF236 HECTD1 SAP130 ERBIN EP300

1.90e-061489721428611215
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

PTBP3 NDC1 MIA2 ARID2 SYNE2 MTERF3 FBXO7 RNF213 PEX14 XIAP AKAP11 RERE HUWE1 GOLGA5

2.01e-061496721432877691
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

MIA2 EP400 XIRP2 ARID2 ATF7IP2 PEX14 PRDM4 SAP130

3.07e-0643072835044719
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

MON2 CCP110 EP400 USO1 N4BP2 ARID2 PFAS HUWE1 TDP2

3.51e-0658872938580884
Pubmed

Hypertonicity-responsive ubiquitin ligase RNF183 promotes Na, K-ATPase lysosomal degradation through ubiquitination of its β1 subunit.

NDC1 USO1 PEX14 XIAP HUWE1 GOLGA5 ERBIN TDP2

4.21e-0644972831732153
Pubmed

A rearranged EP300 gene in the human B-cell lymphoma cell line RC-K8 encodes a disabled transcriptional co-activator that contributes to cell growth and oncogenicity.

REL EP300

4.23e-06272221232847
Pubmed

Identification and characterization of two distinct PPP1R2 isoforms in human spermatozoa.

PPP1R2 PPP1R2B

4.23e-06272223506001
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

PPP1R2 KANSL1 EP400 BACH1 SCAF11 RERE HUWE1 TACC3 ERBIN MED13

4.35e-06774721015302935
Pubmed

Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.

PPP1R2 CCP110 EP400 DYRK1A HUWE1 ERBIN EP300 MED13 PHC1

7.38e-0664572925281560
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

KANSL1 EP400 USO1 DYRK1A REL QSER1 HUWE1 SAP130 EP300 SMAD2

1.06e-05857721025609649
Pubmed

Counter Regulation of Spic by NF-κB and STAT Signaling Controls Inflammation and Iron Metabolism in Macrophages.

BACH1 REL

1.27e-05372232610126
Pubmed

Expression patterns of histone acetyltransferases p300 and CBP during murine tooth development.

EP300 SMAD2

1.27e-05372222179676
Pubmed

CCP5 and CCP6 retain CP110 and negatively regulate ciliogenesis.

CCP110 AGBL5

1.27e-05372237226238
Pubmed

Not so pseudo: the evolutionary history of protein phosphatase 1 regulatory subunit 2 and related pseudogenes.

PPP1R2 PPP1R2B

1.27e-05372224195737
Pubmed

Gene dosage-dependent embryonic development and proliferation defects in mice lacking the transcriptional integrator p300.

EP400 EP300

1.27e-0537229590171
Pubmed

Protein phosphatase PPM1B inhibits DYRK1A kinase through dephosphorylation of pS258 and reduces toxic tau aggregation.

DYRK1A PPM1B

1.27e-05372233380426
Pubmed

Human T-cell leukemia virus type I oncoprotein Tax represses Smad-dependent transforming growth factor beta signaling through interaction with CREB-binding protein/p300.

EP300 SMAD2

1.27e-05372211264182
Pubmed

Histone acetyltransferase p300 is a coactivator for transcription factor REL and is C-terminally truncated in the human diffuse large B-cell lymphoma cell line RC-K8.

REL EP300

1.27e-05372219948376
Pubmed

Histone acetyltransferase-deficient p300 mutants in diffuse large B cell lymphoma have altered transcriptional regulatory activities and are required for optimal cell growth.

REL EP300

1.27e-05372224529102
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

EP400 ARID2 QSER1 HUWE1 TACC3 SAP130 ERBIN EP300

1.81e-0554972838280479
Pubmed

P300 Interacted With N-Myc and Regulated Its Protein Stability via Altering Its Post-Translational Modifications in Neuroblastoma.

EP400 HUWE1 EP300

1.89e-052572336708875
Pubmed

Identification and characterization of BCL-3-binding protein: implications for transcription and DNA repair or recombination.

N4BP2 EP300

2.53e-05472212730195
Pubmed

Growth suppression of human carcinoma cells by reintroduction of the p300 coactivator.

EP300 SMAD2

2.53e-05472212237408
Pubmed

p300-mediated acetylation of COMMD1 regulates its stability, and the ubiquitylation and nucleolar translocation of the RelA NF-κB subunit.

XIAP EP300

2.53e-05472225074812
Pubmed

Binding and modulation of p53 by p300/CBP coactivators.

EP400 EP300

2.53e-0547229194565
Pubmed

The transcriptional co-activator P/CAF potentiates TGF-beta/Smad signaling.

EP300 SMAD2

2.53e-05472211058129
Pubmed

Acetylation of Smad2 by the co-activator p300 regulates activin and transforming growth factor beta response.

EP300 SMAD2

2.53e-05472217478422
Pubmed

Functional architecture of atrophins.

RERE EP300

2.53e-05472217150957
Pubmed

Erbin inhibits transforming growth factor beta signaling through a novel Smad-interacting domain.

ERBIN SMAD2

2.53e-05472217591701
Pubmed

Golgin tethers define subpopulations of COPI vesicles.

USO1 GOLGA5

2.53e-05472215718469
Pubmed

Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS.

PPP1R2 BACH1 DYRK1A AKAP11 USP9Y HECTD1 EP300

3.19e-0543272723455922
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

NDC1 EP400 USO1 RNF213 PEX14 HUWE1 TACC3 GOLGA5 ERBIN

3.21e-0577772935844135
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

MYT1L SYNE2 CHD9 HUWE1

3.30e-058772412465718
Pubmed

Human transcription factor protein interaction networks.

KANSL1 EP400 ARID2 SYNE2 REL SCAF11 RERE QSER1 SAP130 ERBIN TDP2 EP300

3.46e-051429721235140242
Pubmed

Microarray analysis of the Df1 mouse model of the 22q11 deletion syndrome.

PPP1R2 PPP1R2B PPP1R2P1

3.67e-053172315778864
Pubmed

Smad3 induces chondrogenesis through the activation of SOX9 via CREB-binding protein/p300 recruitment.

EP300 SMAD2

4.21e-05572215623506
Pubmed

c-Jun interacts with the corepressor TG-interacting factor (TGIF) to suppress Smad2 transcriptional activity.

EP300 SMAD2

4.21e-05572211371641
Pubmed

Transforming growth factor-beta 1 inhibits non-pathogenic Gram negative bacteria-induced NF-kappa B recruitment to the interleukin-6 gene promoter in intestinal epithelial cells through modulation of histone acetylation.

EP300 SMAD2

4.21e-05572212672795
Pubmed

TGF-beta-stimulated cooperation of smad proteins with the coactivators CBP/p300.

EP300 SMAD2

4.21e-0557229679056
Pubmed

Activity-Based Probes for HECT E3 Ubiquitin Ligases.

HUWE1 HECTD1

4.21e-05572228425671
Pubmed

Cited2 modulates TGF-beta-mediated upregulation of MMP9.

EP300 SMAD2

4.21e-05572216619037
Pubmed

E1A inhibits transforming growth factor-beta signaling through binding to Smad proteins.

EP300 SMAD2

4.21e-05572210497242
Pubmed

Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.

MYT1L ARID2 MTERF3 BACH1 ZNF280B ZNF236 PRDM4 PHC1 SMAD2

4.34e-0580872920412781
Pubmed

Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.

PPP1R2 PTBP3 USO1 CHD9 PFAS HUWE1 HECTD1 ERBIN MED13 PPM1B SMAD2

4.90e-051247721127684187
Pubmed

A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.

PPP1R2 EP400 ARID2 PEX14 TACC3 SAP130 ERBIN

5.59e-0547272738943005
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

PPP1R2 MON2 NDC1 SYNE2 RNF213 PFAS HUWE1 GOLGA5 ERBIN PPM1B

5.88e-051049721027880917
Pubmed

USP2a Supports Metastasis by Tuning TGF-β Signaling.

MYT1L SMAD2

6.31e-05672229490279
Pubmed

p300 modulates HIV-1 gp120-induced apoptosis in human proximal tubular cells: associated with alteration of TGF-beta and Smad signaling.

EP300 SMAD2

6.31e-05672216179804
Pubmed

The F-box protein FBXO7 positively regulates bone morphogenetic protein-mediated signaling through Lys-63-specific ubiquitination of neurotrophin receptor-interacting MAGE (NRAGE).

FBXO7 XIAP

6.31e-05672224947323
Pubmed

DYRK1A interacts with histone acetyl transferase p300 and CBP and localizes to enhancers.

DYRK1A EP300

6.31e-05672230137413
Pubmed

A novel smad nuclear interacting protein, SNIP1, suppresses p300-dependent TGF-beta signal transduction.

EP300 SMAD2

6.31e-05672210887155
Pubmed

Bach1 Represses Wnt/β-Catenin Signaling and Angiogenesis.

BACH1 EP300

6.31e-05672226123998
Pubmed

Degradation, Promoter Recruitment and Transactivation Mediated by the Extreme N-Terminus of MHC Class II Transactivator CIITA Isoform III.

EP400 EP300

6.31e-05672226871568
Pubmed

A human MAP kinase interactome.

KANSL1 N4BP2 ARID2 NAV2 CPLANE1 ERBIN EP300

6.71e-0548672720936779
Pubmed

An AUTS2-Polycomb complex activates gene expression in the CNS.

CSHL1 RERE EP300

6.81e-053872325519132
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

MYT1L FBXO7 DYRK1A XIAP QSER1 HUWE1 NCOA4 CPLANE1 ERBIN SMAD2

7.72e-051084721011544199
Pubmed

Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.

MON2 ARID2 WBP1L DYRK1A PFAS RERE ZNF236 PRDM4 HECTD1 EP300 MED13

8.55e-051327721132694731
Pubmed

The transforming acidic coiled coil proteins interact with nuclear histone acetyltransferases.

TACC3 EP300

8.82e-05772214767476
Pubmed

A Smad transcriptional corepressor.

EP300 SMAD2

8.82e-05772210199400
Pubmed

c-Ski acts as a transcriptional co-repressor in transforming growth factor-beta signaling through interaction with smads.

EP300 SMAD2

8.82e-05772210575014
Pubmed

Pokemon (FBI-1) interacts with Smad4 to repress TGF-β-induced transcriptional responses.

EP300 SMAD2

8.82e-05772225514493
Pubmed

Sox9 and p300 cooperatively regulate chromatin-mediated transcription.

EP300 SMAD2

8.82e-05772216109717
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

MON2 SLC5A11 EP400 ARID2 RNF213 XIAP CHD9 RERE SAP130 EP300

9.81e-051116721031753913
Pubmed

Genome-wide CRISPR screens using isogenic cells reveal vulnerabilities conferred by loss of tumor suppressors.

LRCH2 ARID2 DYRK1A HECTD1 SAP130 MED13

1.02e-0435972635559673
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

MYT1L SYNE2 NAV2 AKAP11 ERBIN

1.07e-0422572512168954
Pubmed

Differential regulation of the REGγ-proteasome pathway by p53/TGF-β signalling and mutant p53 in cancer cells.

EP300 SMAD2

1.17e-04872224157709
Pubmed

Growth-dependent repression of human adenine nucleotide translocator-2 (ANT2) transcription: evidence for the participation of Smad and Sp family proteins in the NF1-dependent repressor complex.

EP300 SMAD2

1.17e-04872218215124
Pubmed

Identification of three novel Smad binding proteins involved in cell polarity.

ERBIN SMAD2

1.17e-04872212650946
Pubmed

Acetylation of KLF5 alters the assembly of p15 transcription factors in transforming growth factor-beta-mediated induction in epithelial cells.

EP300 SMAD2

1.17e-04872219419955
Pubmed

Activation of Smad transcriptional activity by protein inhibitor of activated STAT3 (PIAS3).

EP300 SMAD2

1.17e-04872214691252
Pubmed

A systems-wide screen identifies substrates of the SCFβTrCP ubiquitin ligase.

LRCH2 MTERF3 PFAS HUWE1 HECTD1

1.23e-0423272525515538
Pubmed

Regulation of somatic growth by the p160 coactivator p/CIP.

CSHL1 EP300

1.51e-04972211087842
Pubmed

The in vivo brain interactome of the amyloid precursor protein.

PPP1R2 PPP1R2B PPP1R2P1

1.55e-045072317934213
Pubmed

Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.

PPP1R2B NDC1 SYNE2 PEX14 XIAP MUC13 GOLGA5

1.76e-0456872737774976
Pubmed

Tob1 controls dorsal development of zebrafish embryos by antagonizing maternal beta-catenin transcriptional activity.

EP300 SMAD2

1.88e-041072216890162
Pubmed

Nuclear membrane proteins with potential disease links found by subtractive proteomics.

NDC1 SYNE2

1.88e-041072212958361
Pubmed

HIF1A employs CDK8-mediator to stimulate RNAPII elongation in response to hypoxia.

EP300 MED13

1.88e-041072223746844
Pubmed

14-3-3ε and NAV2 interact to regulate neurite outgrowth and axon elongation.

NAV2 ZNF236

1.88e-041072224161943
Pubmed

The DNA sequence of the human X chromosome.

LRCH2 NXF2 XIAP SATL1 HUWE1 BEND2

2.02e-0440772615772651
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

MON2 KANSL1 LRCH2 EP400 RERE ERBIN

2.02e-0440772612693553
Pubmed

Functional proteomics mapping of a human signaling pathway.

KANSL1 HUWE1 PRDM4 SAP130 ERBIN TDP2 SMAD2

2.24e-0459172715231748
Pubmed

Genome-wide impact of the BRG1 SWI/SNF chromatin remodeler on the transforming growth factor beta transcriptional program.

ERBIN SMAD2

2.30e-041172218003620
Pubmed

UM171 Preserves Epigenetic Marks that Are Reduced in Ex Vivo Culture of Human HSCs via Potentiation of the CLR3-KBTBD4 Complex.

XIAP PFAS HUWE1 TACC3 GOLGA5

2.36e-0426772533417871
Pubmed

Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.

EP400 RERE QSER1 SAP130 MED13

2.40e-0426872533640491
Pubmed

A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal.

EP400 QSER1 SAP130 PHC1

2.46e-0414672423892456
InteractionGSK3A interactions

PPP1R2 CCP110 PPP1R2B LRCH2 USO1 PFAS AKAP11 HECTD1 ERBIN SMAD2

5.00e-064647110int:GSK3A
InteractionSOX9 interactions

EP400 ARID2 FBXO7 EP300 SMAD2

2.36e-0597715int:SOX9
InteractionSMAD3 interactions

KANSL1 BACH1 DYRK1A PRDM4 SAP130 ERBIN TDP2 EP300 SMAD2

2.64e-05447719int:SMAD3
InteractionHDAC1 interactions

EP400 USO1 SYNE2 BACH1 PEX14 RERE INPP5F TACC3 GOLGA5 PRDM4 HECTD1 SAP130 EP300 SMAD2

2.70e-0511087114int:HDAC1
InteractionNANOG interactions

EP400 BACH1 REL SCAF11 QSER1 HUWE1 SAP130 EP300 PHC1

4.67e-05481719int:NANOG
InteractionNUP62 interactions

KANSL1 USO1 SYNE2 ATF7IP2 NXF2 PEX14 TACC3

4.92e-05273717int:NUP62
InteractionHNF4A interactions

KANSL1 EP400 ARID2 QSER1 SAP130 EP300 SMAD2

5.15e-05275717int:HNF4A
CoexpressionBUSSLINGER_GASTRIC_IMMUNE_CELLS

PCNX2 PTBP3 HEG1 KANSL1 EP400 ARID2 DYRK1A RNF213 XIAP AKAP11 SCAF11 HUWE1 ERBIN TDP2 EP300 MED13 PPM1B

4.31e-0714927217M40023
CoexpressionMURARO_PANCREAS_BETA_CELL

PPP1R2 PTBP3 SYNE2 FBXO7 NAV2 CHD9 AKAP11 RERE HUWE1 INPP5F NCOA4 PRDM4 HECTD1

1.60e-069467213M39169
CoexpressionGSE40277_EOS_AND_LEF1_TRANSDUCED_VS_CTRL_CD4_TCELL_UP

N4BP2 REL ZNF280B RERE CPLANE1 PPM1B

1.88e-05200726M9171
CoexpressionRAMALHO_STEMNESS_UP

PPP1R2 PPP1R2B MTERF3 BACH1 PPP1R2P1 SMAD2

2.05e-05203726MM1017
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

HEG1 MIA2 SYNE2 DDR2 DYRK1A PEX14 CHD9 AKAP11 INPP5F MED13 PPM1B

2.07e-058567211M4500
CoexpressionNADLER_HYPERGLYCEMIA_AT_OBESITY

PPP1R2 PPP1R2B BACH1 PPP1R2P1

3.32e-0566724MM631
CoexpressionRODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_DN

MON2 MIA2 KANSL1 ARID2 SYNE2 FBXO7 RNF213 CHD9 RERE HECTD1

6.91e-058077210M16651
CoexpressionGSE19888_CTRL_VS_A3R_INHIBITOR_TREATED_MAST_CELL_DN

MIA2 USO1 BACH1 ERBIN MED13

2.02e-04195725M7310
CoexpressionBURTON_ADIPOGENESIS_PEAK_AT_8HR

PPP1R2 PPP1R2B PPP1R2P1

2.11e-0442723MM691
CoexpressionGSE21360_PRIMARY_VS_QUATERNARY_MEMORY_CD8_TCELL_DN

MON2 BACH1 CHD9 ZNF236 ERBIN

2.17e-04198725M7610
CoexpressionGSE2770_TGFB_AND_IL4_ACT_VS_ACT_CD4_TCELL_6H_UP

PTBP3 KANSL1 PEX14 PHC1 SMAD2

2.17e-04198725M6106
CoexpressionGSE21927_C26GM_VS_4T1_TUMOR_MONOCYTE_BALBC_DN

PCNX2 WBP1L SCAF11 PHC1 PPM1B

2.22e-04199725M7607
CoexpressionGSE12366_PLASMA_CELL_VS_MEMORY_BCELL_DN

PTBP3 RNF213 QSER1 TDP2 MED13

2.22e-04199725M3177
CoexpressionVANASSE_BCL2_TARGETS_UP

PPP1R2 PPP1R2B PPP1R2P1

2.27e-0443723MM799
CoexpressionLEE_CALORIE_RESTRICTION_MUSCLE_UP

PPP1R2 PPP1R2B PPP1R2P1

2.27e-0443723MM669
CoexpressionGSE22103_LPS_VS_GMCSF_AND_IFNG_STIM_NEUTROPHIL_DN

CCP110 ARID2 DYRK1A GOLGA5 ZNF236

2.27e-04200725M7791
CoexpressionGSE11961_FOLLICULAR_BCELL_VS_MARGINAL_ZONE_BCELL_UP

SLC5A11 CCP110 DDR2 ATF7IP2 USP9Y

2.27e-04200725M9381
CoexpressionGSE9037_CTRL_VS_LPS_4H_STIM_BMDM_DN

USO1 MTERF3 DYRK1A ERBIN PPM1B

2.27e-04200725M5806
CoexpressionGSE18893_TCONV_VS_TREG_24H_CULTURE_DN

CCP110 N4BP2 RNF213 SCAF11 INPP5F

2.27e-04200725M7289
CoexpressionGSE22886_IGG_IGA_MEMORY_BCELL_VS_BM_PLASMA_CELL_UP

REL AKAP11 HUWE1 TDP2 PHC1

2.27e-04200725M4449
CoexpressionAtlasDevelopingGonad_e16.5_ovary_emap-9563_top-relative-expression-ranked_1000

MYT1L PCNX2 HEG1 KANSL1 SYNE2 BACH1 ATF7IP2 NXF2 NAV2 RNF213 CHD9 SCAF11 INPP5F NCOA4 CPLANE1

3.69e-087957015gudmap_developingGonad_e16.5_ovary_1000
CoexpressionAtlasDevelopingGonad_e14.5_ epididymis_emap-29141_k-means-cluster#3_top-relative-expression-ranked_1000

HEG1 KANSL1 SYNE2 BACH1 NAV2 CHD9 INPP5F CPLANE1

3.37e-06275708gudmap_developingGonad_e14.5_ epididymis_1000_k3
CoexpressionAtlasDevelopingGonad_e14.5_ ovary_emap-6699_top-relative-expression-ranked_1000

HEG1 KANSL1 SYNE2 BACH1 ATF7IP2 NXF2 NAV2 RNF213 CHD9 REL HUWE1 CPLANE1

7.91e-067767012gudmap_developingGonad_e14.5_ ovary_1000
CoexpressionAtlasDevelopingGonad_P2_ovary_emap-30224_k-means-cluster#5_top-relative-expression-ranked_1000

HEG1 NALCN SYNE2 BACH1 NAV2 CPLANE1

1.05e-05151706gudmap_developingGonad_P2_ovary_1000_k5
CoexpressionAtlasDevelopingGonad_e16.5_ovary_emap-9563_k-means-cluster#2_top-relative-expression-ranked_1000

HEG1 KANSL1 SYNE2 BACH1 NAV2 CHD9 CPLANE1

1.07e-05230707gudmap_developingGonad_e16.5_ovary_1000_k2
CoexpressionAtlasDevelopingKidney_e15.5_cortic collect duct_emap-28132_k-means-cluster#4_top-relative-expression-ranked_500

KANSL1 ARID2 XIAP HUWE1 CPLANE1 MED13

1.63e-05163706gudmap_developingKidney_e15.5_cortic collect duct_500_k4
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_top-relative-expression-ranked_2500_k-means-cluster#4

CCP110 PPP1R2B SYNE2 DYRK1A XIAP CHD9 INPP5F HECTD1 SAP130 EP300

2.42e-055957010Facebase_RNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_2500_K4
CoexpressionAtlasDevelopingKidney_e15.5_cortic collect duct_emap-28132_k-means-cluster#3_top-relative-expression-ranked_200

KANSL1 XIAP HUWE1 CPLANE1

3.02e-0554704gudmap_developingKidney_e15.5_cortic collect duct_200_k3
CoexpressionAtlasDevelopingGonad_e16.5_ovary_emap-9563_top-relative-expression-ranked_500

MYT1L HEG1 SYNE2 BACH1 ATF7IP2 NXF2 RNF213 CPLANE1

3.99e-05387708gudmap_developingGonad_e16.5_ovary_500
CoexpressionAtlasDevelopingGonad_e18.5_ovary_emap-12283_top-relative-expression-ranked_1000

MYT1L PCNX2 HEG1 KANSL1 SYNE2 BACH1 NXF2 NAV2 RNF213 SCAF11 CPLANE1

4.48e-057787011gudmap_developingGonad_e18.5_ovary_1000
CoexpressionAtlasDevelopingGonad_e16.5_epididymis_emap-29702_top-relative-expression-ranked_500

HEG1 KANSL1 NALCN SYNE2 BACH1 NAV2 CHD9 CPLANE1

5.59e-05406708gudmap_developingGonad_e16.5_epididymis_500
CoexpressionAtlasDevelopingGonad_e12.5_ovary_emap-28876_top-relative-expression-ranked_1000

HEG1 KANSL1 SYNE2 BACH1 NAV2 RNF213 CHD9 SCAF11 HUWE1 NCOA4 CPLANE1

6.03e-058047011gudmap_developingGonad_e12.5_ovary_1000
CoexpressionAtlasDevelopingGonad_P2_ovary_emap-30224_k-means-cluster#2_top-relative-expression-ranked_500

HEG1 SYNE2 BACH1 CPLANE1

6.30e-0565704gudmap_developingGonad_P2_ovary_500_k2
CoexpressionAtlasDevelopingGonad_e14.5_ epididymis_emap-29141_top-relative-expression-ranked_500

HEG1 KANSL1 NALCN SYNE2 BACH1 CHD9 SCAF11 CPLANE1

6.30e-05413708gudmap_developingGonad_e14.5_ epididymis_500
CoexpressionAtlasDevelopingGonad_e18.5_ovary_emap-12283_k-means-cluster#2_top-relative-expression-ranked_1000

HEG1 KANSL1 SYNE2 BACH1 NAV2 CPLANE1

6.74e-05210706gudmap_developingGonad_e18.5_ovary_1000_k2
CoexpressionAtlasDevelopingGonad_e14.5_ ovary_emap-6699_k-means-cluster#3_top-relative-expression-ranked_1000

HEG1 KANSL1 BACH1 NAV2 CHD9 CPLANE1

9.86e-05225706gudmap_developingGonad_e14.5_ ovary_1000_k3
CoexpressionAtlasDevelopingKidney_e15.5_Cap mesenchyme_emap-27738_k-means-cluster#5_top-relative-expression-ranked_500

KANSL1 XIAP HUWE1 MED13

1.29e-0478704gudmap_developingKidney_e15.5_Cap mesenchyme_500_k5
CoexpressionAtlasDevelopingGonad_P2_epididymis_emap-30199_k-means-cluster#3_top-relative-expression-ranked_1000

HEG1 KANSL1 SYNE2 BACH1 NAV2 CHD9

1.71e-04249706gudmap_developingGonad_P2_epididymis_1000_k3
CoexpressionAtlasDevelopingGonad_e12.5_ovary_emap-28876_k-means-cluster#3_top-relative-expression-ranked_500

HEG1 KANSL1 BACH1 NAV2 CHD9

1.92e-04161705gudmap_developingGonad_e12.5_ovary_k3_500
CoexpressionAtlasDevelopingGonad_e16.5_epididymis_emap-29702_k-means-cluster#2_top-relative-expression-ranked_500

HEG1 KANSL1 BACH1 NAV2 CHD9

1.97e-04162705gudmap_developingGonad_e16.5_epididymis_500_k2
CoexpressionAtlasDevelopingGonad_P2_ovary_emap-30224_top-relative-expression-ranked_1000

MYT1L PCNX2 HEG1 NALCN SYNE2 BACH1 NAV2 RNF213 SCAF11 CPLANE1

2.06e-047707010gudmap_developingGonad_P2_ovary_1000
CoexpressionAtlasDevelopingGonad_e14.5_ epididymis_emap-29141_top-relative-expression-ranked_1000

HEG1 KANSL1 NALCN SYNE2 BACH1 NAV2 CHD9 SCAF11 INPP5F CPLANE1

2.82e-048017010gudmap_developingGonad_e14.5_ epididymis_1000
CoexpressionAtlasDevelopingGonad_e12.5_ovary_emap-28876_k-means-cluster#3_top-relative-expression-ranked_1000

HEG1 KANSL1 SYNE2 BACH1 NAV2 CHD9

3.04e-04277706gudmap_developingGonad_e12.5_ovary_k3_1000
CoexpressionAtlasDevelopingGonad_e18.5_epididymis_emap-13166_k-means-cluster#3_top-relative-expression-ranked_1000

HEG1 KANSL1 SYNE2 BACH1 NAV2 CHD9

3.28e-04281706gudmap_developingGonad_e18.5_epididymis_1000_k3
CoexpressionAtlasDevelopingGonad_e14.5_ ovary_emap-6699_k-means-cluster#1_top-relative-expression-ranked_500

HEG1 SYNE2 BACH1 CPLANE1

3.47e-04101704gudmap_developingGonad_e14.5_ ovary_500_k1
CoexpressionAtlasFacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_1000

EBF2 PPP1R2B KANSL1 SYNE2 MTERF3 DYRK1A RNF213 QSER1 TACC3 NCOA4 SMAD2

3.68e-049897011Facebase_RNAseq_e10.5_Maxillary Arch_1000
CoexpressionAtlaskidney_e13.5_Podocyte_MafB_k-means-cluster#1_top-relative-expression-ranked_500

ECSCR MTERF3 RNF213

3.85e-0443703gudmap_kidney_e13.5_Podocyte_MafB_k1_500
CoexpressionAtlasDevelopingGonad_e12.5_ovary_emap-28876_top-relative-expression-ranked_500

HEG1 KANSL1 SYNE2 BACH1 NAV2 RNF213 CHD9

3.94e-04409707gudmap_developingGonad_e12.5_ovary_500
CoexpressionAtlasDevelopingGonad_e14.5_ epididymis_emap-29141_k-means-cluster#2_top-relative-expression-ranked_500

HEG1 KANSL1 SYNE2 CPLANE1

4.33e-04107704gudmap_developingGonad_e14.5_ epididymis_500_k2
CoexpressionAtlasFacebaseRNAseq_e9.5_Mandibular Arch_top-relative-expression-ranked_2500_k-means-cluster#2

PPP1R2B ARID2 DYRK1A XIAP CHD9 QSER1 NCOA4 HECTD1

5.24e-04564708Facebase_RNAseq_e9.5_Mandibular Arch_2500_K2
CoexpressionAtlasDevelopingKidney_e15.5_Pelvic Mesenchyme_emap-8241_k-means-cluster#5_top-relative-expression-ranked_1000

KANSL1 ARID2 XIAP CPLANE1 MED13

5.31e-04201705gudmap_developingKidney_e15.5_Pelvic Mesenchyme_1000_k5
CoexpressionAtlasDevelopingKidney_e15.5_anlage of loop of Henle_emap-31283_k-means-cluster#3_top-relative-expression-ranked_500

KANSL1 ARID2 XIAP HUWE1 MED13

5.31e-04201705gudmap_developingKidney_e15.5_500_k3
CoexpressionAtlasFacebaseRNAseq_e9.5_Mandibular Arch_top-relative-expression-ranked_1000_k-means-cluster#4

PPP1R2B SYNE2 DYRK1A CHD9 NCOA4

5.56e-04203705Facebase_RNAseq_e9.5_Mandibular Arch_1000_K4
CoexpressionAtlasDevelopingKidney_e15.5_Medullary collecting duct_emap-28063_k-means-cluster#3_top-relative-expression-ranked_500

KANSL1 XIAP CPLANE1 MED13

6.06e-04117704gudmap_developingKidney_e15.5_Medullary collecting duct_500_k3
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_k-means-cluster#2_top-relative-expression-ranked_500

KANSL1 DYRK1A XIAP CPLANE1 MED13

6.34e-04209705gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_500_k2
CoexpressionAtlasDevelopingKidney_e15.5_ureter tip_flank cortic collct_emap-27752_k-means-cluster#4_top-relative-expression-ranked_200

KANSL1 XIAP MED13

6.38e-0451703gudmap_developingKidney_e15.5_ureter tip_flank cortic collct_200_k4
CoexpressionAtlasDevelopingGonad_e11.5_ovary + mesonephros_emap-3226_k-means-cluster#2_top-relative-expression-ranked_1000

HEG1 KANSL1 SYNE2 BACH1 CHD9 CPLANE1

6.85e-04323706gudmap_developingGonad_e11.5_ovary + mesonephros_k2_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k-means-cluster#2_top-relative-expression-ranked_1000

PTBP3 KANSL1 DYRK1A XIAP CPLANE1 MED13

7.65e-04330706DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k2_1000
CoexpressionAtlasDevelopingGonad_e16.5_epididymis_emap-29702_k-means-cluster#4_top-relative-expression-ranked_1000

HEG1 SYNE2 NAV2 CPLANE1

8.25e-04127704gudmap_developingGonad_e16.5_epididymis_1000_k4
CoexpressionAtlasDevelopingKidney_e15.5_Proximal Tubules_emap-28005_k-means-cluster#2_top-relative-expression-ranked_500

KANSL1 XIAP HUWE1

8.39e-0456703gudmap_developingKidney_e15.5_Proximal Tubules_500_k2
CoexpressionAtlasFacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_2500_k-means-cluster#1

NDC1 SYNE2 SCAF11 RERE HUWE1 GOLGA5 NCOA4 CPLANE1 ERBIN

1.02e-03780709Facebase_RNAseq_e10.5_Lateral Nasal Eminence_2500_K1
CoexpressionAtlasFacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_2500_k-means-cluster#5

PPP1R2B SYNE2 DYRK1A XIAP CHD9 QSER1 NCOA4 HECTD1

1.06e-03629708Facebase_RNAseq_e10.5_Maxillary Arch_2500_K5
CoexpressionAtlasDevelopingGonad_e16.5_epididymis_emap-29702_top-relative-expression-ranked_1000

HEG1 KANSL1 NALCN SYNE2 BACH1 NAV2 CHD9 SCAF11 CPLANE1

1.11e-03790709gudmap_developingGonad_e16.5_epididymis_1000
CoexpressionAtlasDevelopingGonad_P2_epididymis_emap-30199_top-relative-expression-ranked_1000

HEG1 KANSL1 NALCN SYNE2 BACH1 NAV2 CHD9 SCAF11 CPLANE1

1.18e-03797709gudmap_developingGonad_P2_epididymis_1000
CoexpressionAtlasDevelopingGonad_e18.5_epididymis_emap-13166_top-relative-expression-ranked_1000

HEG1 KANSL1 NALCN SYNE2 BACH1 NAV2 CHD9 SCAF11 CPLANE1

1.20e-03799709gudmap_developingGonad_e18.5_epididymis_1000
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

MON2 KANSL1 ARID2 SYNE2 DYRK1A RNF213 REL HUWE1 MED13

1.91e-11188719ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCellhuman_hepatoblastoma|World / Sample and Cell Type and Tumor Cluster (all cells)

MON2 KANSL1 ARID2 DYRK1A SCAF11 RERE ERBIN MED13

8.37e-10193718e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1|TCGA-Pancreas / Sample_Type by Project: Shred V9

ARID2 REL SCAF11 NCOA4 SAP130 ERBIN EP300

1.96e-0818671703db813598b67b1e08f759758a1c2023396921fa
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTBP3 SYNE2 XIAP CHD9 AKAP11 SCAF11 ERBIN

2.35e-0819171760c986d2dcbc19d9338c03da6cb5e1d92fd48f8e
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTBP3 SYNE2 XIAP CHD9 AKAP11 SCAF11 ERBIN

2.35e-0819171709db184cb90fe282a14474d7217068c58092c6f8
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTBP3 SYNE2 XIAP CHD9 AKAP11 SCAF11 ERBIN

2.35e-08191717973117730d6ba5f127e7a0bfabfd0ff2ca7ac131
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6|TCGA-Prostate / Sample_Type by Project: Shred V9

N4BP2 XIAP SCAF11 HUWE1 CPLANE1 HECTD1 MED13

2.53e-08193717abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCelldroplet-Marrow-nan-3m-Myeloid-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MIA2 CHD9 REL SCAF11 ERBIN EP300

4.65e-07182716f8c73baaaca145e2efc48f10f636feb79c8fc779
ToppCelldroplet-Marrow-nan-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MIA2 CHD9 REL SCAF11 ERBIN EP300

4.95e-071847161154a5ad7b8512272b7476f949ddac350910bfb7
ToppCelldroplet-Marrow-nan-3m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MIA2 CHD9 REL SCAF11 ERBIN EP300

5.11e-071857167adfa929930cfa795cbfbd9f1a0b439e08aa765d
ToppCellhuman_hepatoblastoma-Tumor_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

MON2 KANSL1 ARID2 SCAF11 RERE MED13

6.35e-07192716916fbec1c7ab7969bda711886ac88e877e30c280
ToppCellCOVID-19_Mild|World / Disease group, lineage and cell class

KANSL1 BACH1 RNF213 REL SCAF11 ERBIN

7.38e-071977165c33454b10023decd2f5ccda9229b6512659711e
ToppCellmild-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

MON2 KANSL1 CD226 SYNE2 RNF213 USP9Y

7.83e-07199716f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCellcellseq-Immune-Hematopoietic-Megakaryocyte/Platelet-Megakaryocyte/Platelet|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CD226 TACC3 NCOA4 BEND2 TMEM40

8.18e-06172715d0c3fb48c61762dcefca858cf13c9da8eb6d0f5e
ToppCellcellseq-Immune-Hematopoietic-Megakaryocyte/Platelet|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CD226 TACC3 NCOA4 BEND2 TMEM40

8.18e-06172715eb2915165cab2660511e4b70c3a6d3ab2f770809
ToppCellPCW_13-14-Hematologic_ErythroMegGranulo-Hem_ErythroMeg|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

XIRP2 CD226 NCOA4 BEND2 TMEM40

8.89e-06175715c33317d8d60ea88ec326daf91dfd3416a62f9938
ToppCelldroplet-Heart-nan-3m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HEG1 XIRP2 CHD9 SCAF11 ERBIN

9.14e-06176715749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCell10x5'-Liver-Lymphocytic_T_CD4-T_CD4/CD8|Liver / Manually curated celltypes from each tissue

KANSL1 ARID2 SYNE2 RNF213 HUWE1

1.05e-05181715f2315414e714ac86211546a935660c4be6e85f1b
ToppCellPCW_10-12-Hematologic_ErythroMegGranulo-Hem_ErythroMeg|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

XIRP2 FBXO7 NCOA4 BEND2 TMEM40

1.19e-051867151c39ced3b32dba2832991284720b6c5f508a2e73
ToppCellCV-Moderate-7|CV / Virus stimulation, Condition and Cluster

MON2 NDC1 ARID2 RNF213 HUWE1

1.19e-051867158571956890fc9894d766ba294a28e376b4aba428
ToppCellLA-01._Fibroblast_I|World / Chamber and Cluster_Paper

EBF2 PCNX2 DDR2 NAV2 CHD9

1.23e-051877154ea486991f66c29728d127171a07b81404ec0b78
ToppCellCD8+_Memory_T_cell-CV-7|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

MON2 NDC1 ARID2 RNF213 HUWE1

1.36e-051917159454f642c3621370fa23640b631301346b300950
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

BACH1 CHD9 REL RERE PRDM4

1.43e-0519371508696a99309f5b088692ddac8cca35413b5e810d
ToppCellNS-critical-d_0-4-Lymphoid-NK|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

HEG1 USO1 DDR2 USP9Y SAP130

1.43e-051937151b29525c5936d1b779253b8c20f059fa091c6127
ToppCellLA-02._Fibroblast_II|World / Chamber and Cluster_Paper

EBF2 PCNX2 DDR2 NAV2 CHD9

1.50e-05195715a78b605b49acd8c9d68716266ca269dafcd910b9
ToppCellfacs-Tongue-nan-3m-Epithelial|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTBP3 SCAF11 HUWE1 NCOA4 ERBIN

1.61e-051987152f03f8897dd7cce6d8296638e14e11ec16bcf624
ToppCellPBMC-Mild|PBMC / Location, Disease Group, Cell group, Cell class (2021.03.09)

KANSL1 BACH1 RNF213 REL ERBIN

1.61e-0519871544417089b62056269cac38d3134ff209c05b7007
ToppCellfacs-Tongue-nan-3m|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTBP3 SCAF11 HUWE1 NCOA4 ERBIN

1.61e-05198715f2a4057f038ef7225a5b98a7ab068c30dff4eadd
ToppCellPBMC-Mild|PBMC / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

KANSL1 BACH1 RNF213 REL ERBIN

1.61e-0519871528ef3fc4c17dcb765537b75917f7db78baa522db
ToppCellfacs-Tongue-nan-3m-Epithelial-nan|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTBP3 SCAF11 HUWE1 NCOA4 ERBIN

1.65e-051997158d50e1ee58710d896c0204937331d9f4dcd38de0
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

KANSL1 SYNE2 RNF213 REL SCAF11

1.69e-0520071512f1685ce8f218433068e090c9d839cd5a1910bf
ToppCellTCGA-Peripheral_Nervous_System-Primary_Tumor-Paraganglioma-Paraganglioma-3|TCGA-Peripheral_Nervous_System / Sample_Type by Project: Shred V9

USO1 CHD9 SCAF11 PHC1

6.45e-05135714ac20133d4a36f48338b45bffb13e842cb66f83ad
ToppCellPCW_05-06-Hematologic_ErythroMegGranulo-Hem_ErythroMeg-im_megakaryocyte2_(17)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

XIRP2 CD226 BEND2 TMEM40

9.69e-051507146d65df8c0937b498585d1e79919ec73daa354e21
ToppCellPCW_10-12-Hematologic_ErythroMegGranulo-Hem_ErythroMeg-im_megakaryocyte1_(20)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

XIRP2 CD226 BEND2 TMEM40

1.13e-04156714c380142e49b1e4ecacbf37587aafa57f8562b6ad
ToppCellPCW_07-8.5-Hematologic_ErythroMegGranulo-Hem_ErythroMeg-im_megakaryocyte2_(17)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

XIRP2 CD226 BEND2 TMEM40

1.18e-04158714f366c3532e7ef591e1051c172c92db41eb8c57f0
ToppCell15-Distal-Immune-Immune|Distal / Age, Tissue, Lineage and Cell class

XIRP2 CD226 BEND2 TMEM40

1.30e-04162714e190c496ed1e206b86566edfee23c99a99fe90d0
ToppCellSmart-seq2-spleen_(Smart-seq2)-hematologic|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

XIRP2 NCOA4 BEND2 TMEM40

1.30e-0416271430192fa685091230e359323a7281b8a018af98cd
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

BACH1 CHD9 RERE PRDM4

1.34e-041637146bed27d2f67a430a847da5eb47878d14b4949c45
ToppCellPCW_13-14-Hematologic_ErythroMegGranulo-Hem_ErythroMeg-im_megakaryocyte2_(17)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

XIRP2 CD226 BEND2 TMEM40

1.40e-04165714d2ab667ff53f538b12ee4e07ea4b4d118600a228
ToppCell3'-GW_trimst-1.5-LargeIntestine-Endothelial-lymphatic_endothelial|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NALCN ECSCR BACH1 REL

1.43e-04166714941d6aa94ab9d36e5f6c40f446c926754e070d56
ToppCell3'-GW_trimst-1.5-LargeIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NALCN ECSCR BACH1 REL

1.43e-041667146f5ecf3b2cf613ae0535ab3d21d93622f1497571
ToppCellwk_15-18-Hematologic-Meg-ery-Megakaryocyte|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

XIRP2 CD226 BEND2 TMEM40

1.53e-04169714d571e84e01e3316748d4407ed98881b17484e035
ToppCellPCW_10-12-Hematologic_ErythroMegGranulo-Hem_ErythroMeg-im_megakaryocyte2_(17)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

XIRP2 CD226 BEND2 TMEM40

1.57e-041707143886a77bc3ddbeb42a8149b759fe578871676d6e
ToppCellwk_20-22-Hematologic-Meg-ery-Megakaryocyte|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

XIRP2 CD226 BEND2 TMEM40

1.57e-04170714eace4dd09cdbde0fa40a6aa0f3dba1114d0ce475
ToppCellwk_08-11-Hematologic-Meg-ery-Megakaryocyte|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

XIRP2 CD226 BEND2 TMEM40

1.60e-041717149dda25df493766723335851b3c3d89735b6e8051
ToppCellfacs|World / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HEG1 PFAS MUC13 SAP130

1.60e-04171714c9990bc041a632b2f7bbebbfe737772c423d7027
ToppCellfacs-Lung-3m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell-CD4-positive,_alpha-beta_T_cell_l21|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

N4BP2 TACC3 GOLGA5 PPM1B

1.60e-04171714f1fdc0ec3399ed6955976d02be7e5fc329a64276
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-B_cell|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

BACH1 CHD9 RERE PRDM4

1.68e-04173714d56e337eae727a29cd53cfd628e1b3c0a98e1f51
ToppCell3'-GW_trimst-1-LargeIntestine-Hematopoietic-Myeloid-Megakaryocyte|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

XIRP2 CD226 BEND2 TMEM40

1.75e-04175714901f0181a30e5cc609dcada8d8a59f0468df6fa5
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells-|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PCNX2 CD226 ZSCAN30 ZNF280B

1.75e-0417571426bd957498e41a3f1ffa60d3effa27ca8c4ba631
ToppCellCOVID-19-lung-RBC|COVID-19 / Disease (COVID-19 only), tissue and cell type

CD226 FBXO7 TACC3 TMEM40

1.75e-041757144c35292ad2ac712ba7516f27dd6eac6ba8fdd163
ToppCellPBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SYNE2 RNF213 CPLANE1 ERBIN

1.83e-04177714d3e6c768b88b7906f3c7fdd00ba20842212c14b1
ToppCellPBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SYNE2 RNF213 CPLANE1 ERBIN

1.83e-04177714f8f101c772c043636bedd6b2ec81409b1d2599bf
ToppCellCV-Severe-7|Severe / Virus stimulation, Condition and Cluster

KANSL1 ARID2 RNF213 HUWE1

1.83e-0417771482fdd6185b368f54f03de389427cbe3071d21a99
ToppCellCOVID-19_Mild-Lymphoid_T/NK-NK_activated|COVID-19_Mild / Disease group, lineage and cell class

SYNE2 RNF213 CPLANE1 ERBIN

1.83e-041777146978a22fef40c8b455342373abe7593f5ede0fa4
ToppCellPBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

SYNE2 RNF213 CPLANE1 ERBIN

1.83e-04177714936ab2b180a052387124f68d0c7f41c0b164e748
ToppCellPBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SYNE2 RNF213 CPLANE1 ERBIN

1.83e-04177714d5aeda113afaa2425874394610344570c9078478
ToppCell3'-GW_trimst-1-SmallIntestine-Hematopoietic-Myeloid-Megakaryocyte|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

XIRP2 CD226 BEND2 TMEM40

1.91e-041797148d9bad6507fac0926163807a0bda62a57e7660e3
ToppCellwk_20-22-Hematologic-Meg-ery|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

FBXO7 NCOA4 BEND2 TMEM40

1.99e-04181714d0637f9ccec5dba4997520b27287989522e04f96
ToppCellPCW_13-14-Hematologic_ErythroMegGranulo|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

CD226 NCOA4 BEND2 TMEM40

2.04e-04182714e5e16abf4d3bd5a97e7c573b99f7a3d9a5add120
ToppCellCOVID-19_Mild|World / Disease Group and Platelet Clusters

XIRP2 SYNE2 ERBIN TMEM40

2.04e-0418271490c61e10c7860bfba6ccfe6f37671c8924637f7b
ToppCell10x5'v1-week_12-13-Hematopoietic-MK-MK|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

XIRP2 CD226 BEND2 TMEM40

2.08e-041837146cbc88c27dc957d182526e84824f70c8e860bf74
ToppCell10x3'2.3-week_17-19-Hematopoietic-MK-MK|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

XIRP2 CD226 BEND2 TMEM40

2.12e-04184714ba65e3972b2b8d825a2c1a9d03d092cc1afad073
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NALCN DDR2 NAV2 BEND2

2.12e-04184714e061e85c4bb19f49f6451ddd7a9077d7378ee365
ToppCellCV-Moderate-7|Moderate / Virus stimulation, Condition and Cluster

MON2 NDC1 RNF213 HUWE1

2.17e-04185714a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BACH1 REL HUWE1 ERBIN

2.17e-04185714eb7d3c1363d5fedc611f9c1a91ea823de251355e
ToppCellmegakaryocytic-Platelet|megakaryocytic / Lineage and Cell class

CD226 NCOA4 BEND2 TMEM40

2.17e-04185714436f0ab9016c5b8b7315d5974de80af6b3a999d2
ToppCellCOVID-19_Convalescent-PLT_4|World / Disease Group and Platelet Clusters

XIRP2 BACH1 CHD9 ZNF236

2.21e-041867145954a1e3ffafb33f2a9bc87af3343f304fda4c92
ToppCellremission-Platelet|World / disease stage, cell group and cell class

XIRP2 NCOA4 BEND2 TMEM40

2.31e-04188714fa69f20ef6b8ce620ba342f0984d40ddf259bc3f
ToppCelldroplet-Tongue-nan|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYNE2 BACH1 REL SCAF11

2.31e-04188714d62cc37e86b7b186e53aeb7f421c4e5ee28f23bd
ToppCellLV-01._Fibroblast_I|World / Chamber and Cluster_Paper

EBF2 PTBP3 DDR2 CHD9

2.40e-0419071412992ec80a7b4f4f17de693f0719ee061a9918fd
ToppCellsevere-Platelet|severe / disease stage, cell group and cell class

XIRP2 CD226 BEND2 TMEM40

2.40e-04190714497ec3fe4dd6f1b4fa6e76d9ac07df497efce7a2
ToppCellRV-01._Fibroblast_I|World / Chamber and Cluster_Paper

EBF2 PTBP3 DDR2 CHD9

2.45e-0419171470c067c54084bfb02c29bab085f4defd477194fb
ToppCellPBMC-Severe-Hematopoietic-Platelet-Platelet-plt_0|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CD226 NCOA4 BEND2 TMEM40

2.50e-041927145bf420b03c32d7bbc919616bcb7d69f3e3a459ed
ToppCell10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

MON2 KANSL1 SYNE2 RNF213

2.50e-0419271447646d7e4990be85072987f92bf18d52f8da752e
ToppCellPBMC-Severe-Hematopoietic-Platelet-Platelet-plt_0|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CD226 NCOA4 BEND2 TMEM40

2.50e-0419271497975340f9ab3ab6e0aa7751b10e008ff3d21bf2
ToppCellfacs-Aorta-Heart-3m|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HEG1 XIAP SCAF11 ERBIN

2.50e-041927141ccc47792edf9ee23501c8e2165d11271636b66a
ToppCellfacs-Brain_Myeloid-Hippocampus-3m-Myeloid|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BACH1 CHD9 SCAF11 ERBIN

2.55e-0419371406b65110db974f4ef90d3511ff34428976a52c9c
ToppCellfacs-Brain_Myeloid-Hippocampus-3m-Myeloid-microglial_cell|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BACH1 CHD9 SCAF11 ERBIN

2.55e-041937149c16032bc03df8760ae199e8f19fdafa4c3f1827
ToppCell10x5'-blood|World / Manually curated celltypes from each tissue

RNF213 NCOA4 BEND2 TMEM40

2.55e-04193714359d4242a7e5e51a3eaf6fe51bc1c653a402b054
ToppCellfacs-Brain_Myeloid-Hippocampus-3m|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BACH1 CHD9 SCAF11 ERBIN

2.55e-04193714a4f91bca5eaa985982d33a528f7566ffde154d47
ToppCellMegakaryocytic-erythropoietic-Megakaryo-cells-Platelet|Megakaryocytic-erythropoietic / Lineage, cell class and subclass

CD226 NCOA4 BEND2 TMEM40

2.55e-0419371406ddaeb2fd32895181e23f3f1bb3e9103e79752c
ToppCellLA|World / Chamber and Cluster_Paper

EBF2 PCNX2 DDR2 NAV2

2.55e-04193714d4bf89437216baf489ea0239136dcedf3b6714af
ToppCellfacs-Brain_Myeloid-Hippocampus-3m-Myeloid-nan|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BACH1 CHD9 SCAF11 ERBIN

2.55e-04193714b39d7feaac4ff8f7409cd3d15e8f3c6391367275
ToppCellTCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_NOS-3|TCGA-Stomach / Sample_Type by Project: Shred V9

EBF2 HEG1 NALCN DDR2

2.60e-041947142260cd817a6661e5eb6645b0c6786e18fd58371e
ToppCellLA-02._Fibroblast_II|LA / Chamber and Cluster_Paper

EBF2 DDR2 NAV2 CHD9

2.60e-04194714234d1494c114cce77c619708bbcd8d5ce805f19b
ToppCellfacs-Brain_Myeloid-Hippocampus|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ECSCR BACH1 CHD9 SCAF11

2.65e-04195714a1478021a3ed0e779716393124ca2a7770c433b7
ToppCellRV-02._Fibroblast_II|World / Chamber and Cluster_Paper

EBF2 PTBP3 DDR2 CHD9

2.65e-04195714ce90b30dcdb56d4cd925cdb79fd9d7cefd998f48
ToppCellRA-02._Fibroblast_II|RA / Chamber and Cluster_Paper

EBF2 DDR2 NAV2 CHD9

2.65e-041957146a02ebbeb3199447ddce64d92d8809436e040eba
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAV2 SCAF11 RERE HUWE1

2.65e-041957147796ea9247f4c63762f0de8490fed08b9717fa23
ToppCellBronchial-NucSeq|Bronchial / Cell types per location group and 10X technology with lineage, and cell group designations

KANSL1 DYRK1A NAV2 RERE

2.70e-04196714ab53c742866945545a92e2e61850d63c80d9a2a6
ToppCellCOVID-19_Mild-Classical_Monocyte-cMono_4|COVID-19_Mild / Disease condition and Cell class

BACH1 RNF213 REL ERBIN

2.70e-041967143729d1444c65cad640377894decc64129bc3fd5b
ToppCellmild_COVID-19_(asymptomatic)|World / disease group, cell group and cell class (v2)

BACH1 XIAP REL ERBIN

2.70e-041967148cb3dcb3e5732f4bb060c87ca339b8997a1a8cd4
ToppCellmild-low-quality_cells|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

CD226 SYNE2 RNF213 USP9Y

2.75e-04197714e4331969bd911d1ebb5453f40a7057297b5389b4
ToppCellT_cells-Treg_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

PCNX2 SYNE2 INPP5F TACC3

2.75e-04197714de5448fcdf4e433fc167496413abe5d0c8a5c6d8
ToppCellLPS_only-Endothelial-Endothelial-FOXM1|LPS_only / Treatment groups by lineage, cell group, cell type

SLC5A11 CCP110 NAV2 TACC3

2.75e-04197714038fd92750257d43d5e980fd06d77742b543f11a
ToppCellParenchymal-NucSeq|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations

KANSL1 DYRK1A NAV2 RERE

2.81e-041987141996373bdccc55aac347d349bd22f6aad6d0c668
ToppCell(11)_FOXN4+-(2)_GFP_FOXI1|(11)_FOXN4+ / shred by cell type by condition

PTBP3 SYNE2 XIAP SCAF11

2.81e-0419871476d40b8c2f8399725b3a62ee2ae0896559cf91eb
ToppCellCOVID_vent-Lymphocytic-ILC|COVID_vent / Disease condition, Lineage, Cell class and subclass

HEG1 CD226 SYNE2 RNF213

2.86e-04199714e3ff7fa1b1de1aaf6b46cdf49afa95bad457728a
ToppCell(09)_Interm._secr.>cil.-(2)_GFP_FOXI1|(09)_Interm._secr.>cil. / shred by cell type by condition

PTBP3 SYNE2 XIAP SCAF11

2.86e-04199714fc680f85ebd3bab4c72876a19a461b0afb5f51ce
ComputationalNeighborhood of GSPT1

CHD9 CPLANE1 PRDM4 HECTD1 SAP130 PHC1 PPM1B

8.97e-06169487GCM_GSPT1
ComputationalNeighborhood of UBE2N

CHD9 HECTD1 SAP130 MED13 PPM1B SMAD2

5.86e-05154486GCM_UBE2N
ComputationalNeighborhood of RAB10

MON2 CPLANE1 HECTD1 SAP130 ERBIN PPM1B

1.23e-04176486GCM_RAB10
ComputationalNeighborhood of BAG5

XIAP HECTD1 SAP130

6.32e-0438483GCM_BAG5
ComputationalNeighborhood of MYST2

CHD9 QSER1 SAP130 MED13 PHC1

9.71e-04172485GCM_MYST2
DrugSanguinarine [2447-54-3]; Down 200; 12uM; MCF7; HT_HG-U133A

PTBP3 CCP110 EP400 SYNE2 BACH1 AKAP11 SCAF11

2.01e-061917074168_DN
Diseaserespiratory symptom change measurement, response to placebo

EBF2 ATF7IP2 NAV2

8.49e-0617703EFO_0008344, EFO_0010068
Diseaseintellectual disability (implicated_via_orthology)

KANSL1 ATF7IP2 DYRK1A ZNF280B

3.11e-0575704DOID:1059 (implicated_via_orthology)
DiseaseParkinson disease

KANSL1 WBP1L DYRK1A RERE INPP5F MED13

1.16e-04321706MONDO_0005180
Diseaselegumain measurement

GOLGA5 PHC1

1.16e-047702EFO_0020530
Diseaseprostate carcinoma

EBF2 SYNE2 RNF213 PEX14 ZNF280B QSER1 ZNF236 SMAD2

1.21e-03891708EFO_0001663
Diseaseidiopathic pulmonary fibrosis (is_marker_for)

EP300 SMAD2

1.36e-0323702DOID:0050156 (is_marker_for)
Diseasesmoking status measurement

MYT1L MON2 EBF2 KANSL1 NECAB1 WBP1L NAV2 RERE QSER1

1.64e-031160709EFO_0006527
DiseaseAdenoid Cystic Carcinoma

KANSL1 ERBIN EP300

1.75e-03100703C0010606
Diseaseovarian carcinoma (is_marker_for)

NCOA4 SMAD2

2.02e-0328702DOID:4001 (is_marker_for)

Protein segments in the cluster

PeptideGeneStartEntry
DTFHTMNTQQSTPSN

ZNF280B

206

Q86YH2
SSSSQQNSPQMKNSP

AGBL5

651

Q8NDL9
SNQNNSNCSSPSRMS

ERBIN

651

Q96RT1
SGQAPVSQAQMSSSS

EP300

786

Q09472
PAQNATSSQDSSQDT

EP400

756

Q96L91
QESQQMSTATSEQAG

BACH1

696

O14867
ANQSSNLTATQMSFP

ARID2

656

Q68CP9
NNQVPTAMSSSSTPQ

ARID2

981

Q68CP9
TPQQSNYSTSSNSMN

EBF2

466

Q9HAK2
SDSIPTSSNMEETQQ

CSHL1

86

Q14406
EDFQSTESVSSQQMN

AKAP11

1711

Q9UKA4
NSVSTSPAMEQSQSS

DYRK1A

491

Q13627
MHSSQNVQTQESSSP

QSER1

496

Q2KHR3
MVNSTSPQSQLNDSS

SLC17A3

66

O00476
TDATTTSNNTNPGMT

MGAM2

2276

Q2M2H8
SLPSDSSMFNNNRSS

DDR2

446

Q16832
SSMFNNNRSSSPSEQ

DDR2

451

Q16832
RLEQQMNSASGSSSN

GOLGA5

621

Q8TBA6
ESMNTEESNQGSTAS

PPP1R2P1

181

Q96PQ5
DTNTENSVNTMNRST

BEND2

441

Q8NDZ0
MTASSQLNGSAEQNE

PCNX2

591

A6NKB5
NSTANKSSVNSMEQP

KANSL1

226

Q7Z3B3
SSSEVQNGSPMSQTE

HEG1

426

Q9ULI3
QSTEQQDLQSTSDQM

MON2

526

Q7Z3U7
SNDSTEQNLSDGTPM

HUWE1

2726

Q7Z6Z7
ESMNTEESNQGSTPS

PPP1R2

181

P41236
MNTFQDQSGSSSNRE

NCOA4

1

Q13772
SPNMTSCSVSNSQQF

CHD9

256

Q3L8U1
TNNMNLSRSSSDNNT

HECTD1

1561

Q9ULT8
SDQNTTSPGMNSSDE

CPLANE1

2816

Q9H799
NEQPSLATSSNQTSM

FBXO7

101

Q9Y3I1
LATSSNQTSMQDEQP

FBXO7

106

Q9Y3I1
NQTSMQDEQPSDSFQ

FBXO7

111

Q9Y3I1
GHNSQPTMTQTSSSQ

ECSCR

21

Q19T08
TSNSNSSGFTNSAMQ

CCP110

736

O43303
TSGNSSNSPNAEVMA

ATF7IP2

481

Q5U623
TSQPTNQSMDDTRED

CD226

306

Q15762
ENSVTHCSENNMPSS

SCAF11

746

Q99590
MTNQVSNETQSESTE

INPP5F

991

Q9Y2H2
QDSDNANMSTQSPVS

LRCH2

581

Q5VUJ6
SFVSPSLQMEDSNSN

PRDM4

351

Q9UKN5
NSAQSSLLPSMNEQS

MTERF3

81

Q96E29
NSQMVSTDNSLSSQN

MIA2

576

Q96PC5
SSSSEPSLSQEQQEM

NXF2

561

Q9GZY0
ENMKSSQTSGTNEQS

USO1

761

O60763
SSSQSPGSSENQMVS

TACC3

156

Q9Y6A5
TQESSASNQASSPEN

SYNE2

4421

Q8WXH0
QQSKAQAEMQSSASS

NAV2

246

Q8IVL1
MNQSGTNQSSLSDSN

SATL1

1

Q86VE3
PDTSQSCKNQTDMSQ

SATL1

231

Q86VE3
TDMSQPDANQSSLSD

SATL1

241

Q86VE3
QNGMPEASSSSSVQF

SLC5A11

581

Q8WWX8
ATSSNSDAGNPVTMQ

PPM1B

436

O75688
NESDSDSSAQQQMLQ

RERE

721

Q9P2R6
SNAAGSMSTQANTVQ

MED13

1566

Q9UHV7
MASSEQAEQPSQPSS

PEX14

1

O75381
SSQMNSGSSVSADVQ

XIRP2

351

A4UGR9
IADSENNNSTMASAS

RNF213

31

Q63HN8
SFSMNSNDITQQSVD

ZSCAN30

281

Q86W11
NAQKDSMQDESSQTS

XIAP

416

P98170
SETQSNNEMSPTTED

MUC13

136

Q9H3R2
NNEMSPTTEDNQSSG

MUC13

141

Q9H3R2
ESMNTEESNQGSTPS

PPP1R2B

181

Q6NXS1
ETSDQQLNQSMDTGS

SMAD2

231

Q15796
FESIMSTQESSNPNN

PFAS

251

O15067
VSMETVSNQNNDQPT

SAP130

696

Q9H0E3
METSASSSQPQDNSQ

TMEM40

1

Q8WWA1
SPSEDTQQENGSMFS

TDP2

101

O95551
METESEQNSNSTNGS

PHC1

1

P78364
DNSMINESGPSNSTN

REL

571

Q04864
NQTSSPDSSNENSVA

USP9Y

31

O00507
TMNSSTPSTANGNDS

PTBP3

31

O95758
DDSTVDQQSMQASTQ

ZNF236

781

Q9UL36
TINEQDSPNSQSSSS

WBP1L

326

Q9NX94
NSQDNSMQPETSSQQ

NALCN

1626

Q8IZF0
NPDSSNMTPIFSTQN

N4BP2

181

Q86UW6
TESEMNSNTSNSLED

MYT1L

221

Q9UL68
TSASDQQMTEFSNPS

NDC1

486

Q9BTX1
MEDSQETSPSSNNSS

NECAB1

1

Q8N987