Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	peptidase activity	TINAGL1 ADAMTS10 METAP1 ADAMTS1 ADAMTS6 PRSS55 APEH MMP21 IHH KLKB1 CAPN11	2.00e-06	654	57	11	GO:0008233
GeneOntologyMolecularFunction	interleukin-11 receptor activity	IL11RA IL6R	2.40e-05	3	57	2	GO:0004921
GeneOntologyMolecularFunction	interleukin-11 binding	IL11RA IL6R	2.40e-05	3	57	2	GO:0019970
GeneOntologyMolecularFunction	endopeptidase activity	ADAMTS10 ADAMTS1 ADAMTS6 PRSS55 APEH MMP21 KLKB1 CAPN11	2.84e-05	430	57	8	GO:0004175
GeneOntologyMolecularFunction	metallopeptidase activity	ADAMTS10 METAP1 ADAMTS1 ADAMTS6 MMP21	2.63e-04	200	57	5	GO:0008237
GeneOntologyMolecularFunction	metalloendopeptidase activity	ADAMTS10 ADAMTS1 ADAMTS6 MMP21	3.83e-04	120	57	4	GO:0004222
GeneOntologyMolecularFunction	growth factor binding	IL11RA THBS1 NTRK1 IL6R	1.03e-03	156	57	4	GO:0019838
GeneOntologyMolecularFunction	cytokine binding	IL11RA THBS1 POU5F1B IL6R	1.05e-03	157	57	4	GO:0019955
GeneOntologyMolecularFunction	extracellular matrix binding	TINAGL1 THBS1 ADAMTSL5	1.19e-03	73	57	3	GO:0050840
GeneOntologyBiologicalProcess	blood vessel development	ROBO4 THBS1 PDE3B ADAMTS1 ADAMTS6 NTRK1 MMP21 IHH ADGRA2 IL6R HSPB1	4.02e-05	929	57	11	GO:0001568
GeneOntologyBiologicalProcess	vasculature development	ROBO4 THBS1 PDE3B ADAMTS1 ADAMTS6 NTRK1 MMP21 IHH ADGRA2 IL6R HSPB1	5.88e-05	969	57	11	GO:0001944
GeneOntologyBiologicalProcess	extracellular matrix organization	ADAMTS10 ADAMTSL5 ADAMTS1 ADAMTS6 MMP21 IHH ADAMTSL4	7.76e-05	377	57	7	GO:0030198
GeneOntologyBiologicalProcess	extracellular structure organization	ADAMTS10 ADAMTSL5 ADAMTS1 ADAMTS6 MMP21 IHH ADAMTSL4	7.89e-05	378	57	7	GO:0043062
GeneOntologyBiologicalProcess	external encapsulating structure organization	ADAMTS10 ADAMTSL5 ADAMTS1 ADAMTS6 MMP21 IHH ADAMTSL4	8.02e-05	379	57	7	GO:0045229
GeneOntologyBiologicalProcess	interleukin-11-mediated signaling pathway	IL11RA IL6R	1.12e-04	6	57	2	GO:0038154
GeneOntologyCellularComponent	extracellular matrix	TINAGL1 ADAMTS10 THBS1 FCGBP ADAMTSL5 ADAMTS1 ADAMTS6 MMP21 CFP LAMC3 IHH SSPOP ADAMTSL4	1.75e-08	656	57	13	GO:0031012
GeneOntologyCellularComponent	external encapsulating structure	TINAGL1 ADAMTS10 THBS1 FCGBP ADAMTSL5 ADAMTS1 ADAMTS6 MMP21 CFP LAMC3 IHH SSPOP ADAMTSL4	1.81e-08	658	57	13	GO:0030312
GeneOntologyCellularComponent	collagen-containing extracellular matrix	TINAGL1 ADAMTS10 THBS1 ADAMTSL5 ADAMTS1 CFP LAMC3 SSPOP ADAMTSL4	1.23e-05	530	57	9	GO:0062023
GeneOntologyCellularComponent	microfibril	ADAMTS10 ADAMTSL5	5.59e-04	13	57	2	GO:0001527
Domain	TSP_1	ADAMTS10 THBS1 CILP2 ADAMTSL5 ADAMTS1 ADAMTS6 CFP SSPOP ADAMTSL4	2.09e-13	63	56	9	PF00090
Domain	TSP1	ADAMTS10 THBS1 CILP2 ADAMTSL5 ADAMTS1 ADAMTS6 CFP SSPOP ADAMTSL4	2.80e-13	65	56	9	SM00209
Domain	TSP1_rpt	ADAMTS10 THBS1 CILP2 ADAMTSL5 ADAMTS1 ADAMTS6 CFP SSPOP ADAMTSL4	2.80e-13	65	56	9	IPR000884
Domain	TSP1	ADAMTS10 THBS1 CILP2 ADAMTSL5 ADAMTS1 ADAMTS6 CFP SSPOP ADAMTSL4	2.80e-13	65	56	9	PS50092
Domain	ADAM_spacer1	ADAMTS10 ADAMTSL5 ADAMTS1 ADAMTS6 ADAMTSL4	6.52e-09	23	56	5	IPR010294
Domain	ADAM_spacer1	ADAMTS10 ADAMTSL5 ADAMTS1 ADAMTS6 ADAMTSL4	6.52e-09	23	56	5	PF05986
Domain	Peptidase_M12B_ADAM-TS	ADAMTS10 ADAMTSL5 ADAMTS1 ADAMTS6	7.36e-07	24	56	4	IPR013273
Domain	PLAC	ADAMTS10 ADAMTS6 ADAMTSL4	9.08e-06	14	56	3	PF08686
Domain	PLAC	ADAMTS10 ADAMTS6 ADAMTSL4	2.39e-05	19	56	3	PS50900
Domain	PLAC	ADAMTS10 ADAMTS6 ADAMTSL4	2.39e-05	19	56	3	IPR010909
Domain	HEMATOPO_REC_L_F3	IL11RA IL6R	8.78e-05	5	56	2	PS01354
Domain	Hematopoietin_rcpt_L_F3_CS	IL11RA IL6R	8.78e-05	5	56	2	IPR003530
Domain	MetalloPept_cat_dom	ADAMTS10 ADAMTS1 ADAMTS6 MMP21	1.02e-04	81	56	4	IPR024079
Domain	-	ADAMTS10 ADAMTS1 ADAMTS6 MMP21	1.02e-04	81	56	4	3.40.390.10
Domain	VWC	THBS1 FCGBP SSPOP	2.00e-04	38	56	3	SM00214
Domain	ZINC_PROTEASE	ADAMTS10 ADAMTS1 ADAMTS6 MMP21	2.12e-04	98	56	4	PS00142
Domain	GDS_CDC24_CS	ARHGEF7 ARHGEF4 ARHGEF6	2.16e-04	39	56	3	IPR001331
Domain	Peptidase_M12B_N	ADAMTS10 ADAMTS1 ADAMTS6	2.16e-04	39	56	3	IPR002870
Domain	Pep_M12B_propep	ADAMTS10 ADAMTS1 ADAMTS6	2.16e-04	39	56	3	PF01562
Domain	DISINTEGRIN_1	ADAMTS10 ADAMTS1 ADAMTS6	2.33e-04	40	56	3	PS00427
Domain	Reprolysin	ADAMTS10 ADAMTS1 ADAMTS6	2.33e-04	40	56	3	PF01421
Domain	ADAM_MEPRO	ADAMTS10 ADAMTS1 ADAMTS6	2.33e-04	40	56	3	PS50215
Domain	DISINTEGRIN_2	ADAMTS10 ADAMTS1 ADAMTS6	2.33e-04	40	56	3	PS50214
Domain	Peptidase_M12B	ADAMTS10 ADAMTS1 ADAMTS6	2.33e-04	40	56	3	IPR001590
Domain	Disintegrin_dom	ADAMTS10 ADAMTS1 ADAMTS6	2.51e-04	41	56	3	IPR001762
Domain	VWF_dom	THBS1 FCGBP SSPOP	2.70e-04	42	56	3	IPR001007
Domain	TIL	FCGBP SSPOP	5.72e-04	12	56	2	PF01826
Domain	C8	FCGBP SSPOP	5.72e-04	12	56	2	PF08742
Domain	IG_LIKE	IL11RA ROBO4 CILP2 NTRK1 ADGRA2 TAPBP IL6R	6.33e-04	491	56	7	PS50835
Domain	Unchr_dom_Cys-rich	FCGBP SSPOP	6.74e-04	13	56	2	IPR014853
Domain	C8	FCGBP SSPOP	6.74e-04	13	56	2	SM00832
Domain	Ig-like_dom	IL11RA ROBO4 CILP2 NTRK1 ADGRA2 TAPBP IL6R	7.30e-04	503	56	7	IPR007110
Domain	-	IL11RA ROBO4 CILP2 NTRK1 PKHD1 ADGRA2 TAPBP IL6R	7.62e-04	663	56	8	2.60.40.10
Domain	TIL_dom	FCGBP SSPOP	7.85e-04	14	56	2	IPR002919
Domain	DH_1	ARHGEF7 ARHGEF4 ARHGEF6	8.93e-04	63	56	3	PS00741
Domain	VWD	FCGBP SSPOP	1.03e-03	16	56	2	SM00216
Domain	VWF_type-D	FCGBP SSPOP	1.03e-03	16	56	2	IPR001846
Domain	VWFD	FCGBP SSPOP	1.03e-03	16	56	2	PS51233
Domain	VWD	FCGBP SSPOP	1.03e-03	16	56	2	PF00094
Domain	RhoGEF	ARHGEF7 ARHGEF4 ARHGEF6	1.11e-03	68	56	3	SM00325
Domain	Ig-like_fold	IL11RA ROBO4 CILP2 NTRK1 PKHD1 ADGRA2 TAPBP IL6R	1.14e-03	706	56	8	IPR013783
Domain	RhoGEF	ARHGEF7 ARHGEF4 ARHGEF6	1.21e-03	70	56	3	PF00621
Domain	DH_2	ARHGEF7 ARHGEF4 ARHGEF6	1.21e-03	70	56	3	PS50010
Domain	DH-domain	ARHGEF7 ARHGEF4 ARHGEF6	1.26e-03	71	56	3	IPR000219
Domain	-	ARHGEF7 ARHGEF4 ARHGEF6	1.26e-03	71	56	3	1.20.900.10
Domain	VWC_out	FCGBP SSPOP	1.46e-03	19	56	2	SM00215
Domain	IG	IL11RA ROBO4 CILP2 NTRK1 ADGRA2 IL6R	1.59e-03	421	56	6	SM00409
Domain	Ig_sub	IL11RA ROBO4 CILP2 NTRK1 ADGRA2 IL6R	1.59e-03	421	56	6	IPR003599
Domain	THIOL_PROTEASE_HIS	TINAGL1 CAPN11	2.95e-03	27	56	2	PS00639
Domain	Pept_cys_AS	TINAGL1 CAPN11	3.17e-03	28	56	2	IPR000169
Domain	PH	ARHGEF7 TRIOBP ARHGEF4 ARHGEF6	4.91e-03	229	56	4	PF00169
Domain	VWFC_1	THBS1 SSPOP	5.21e-03	36	56	2	PS01208
Domain	VWFC_2	THBS1 SSPOP	5.79e-03	38	56	2	PS50184
Domain	LDLR_class-A_CS	SSPOP MAMDC4	6.40e-03	40	56	2	IPR023415
Domain	Ldl_recept_a	SSPOP MAMDC4	8.05e-03	45	56	2	PF00057
Domain	-	SSPOP MAMDC4	8.40e-03	46	56	2	4.10.400.10
Pathway	REACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS	ADAMTS10 THBS1 ADAMTSL5 ADAMTS1 ADAMTS6 CFP SSPOP ADAMTSL4	9.23e-14	39	39	8	M27417
Pathway	REACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS	ADAMTS10 THBS1 ADAMTSL5 ADAMTS1 ADAMTS6 CFP SSPOP ADAMTSL4	9.23e-14	39	39	8	MM15165
Pathway	REACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS	ADAMTS10 THBS1 ADAMTSL5 ADAMTS1 ADAMTS6 CFP SSPOP ADAMTSL4	1.05e-11	68	39	8	M27303
Pathway	REACTOME_O_LINKED_GLYCOSYLATION	ADAMTS10 THBS1 ADAMTSL5 ADAMTS1 ADAMTS6 CFP SSPOP ADAMTSL4	4.97e-10	109	39	8	MM15164
Pathway	REACTOME_O_LINKED_GLYCOSYLATION	ADAMTS10 THBS1 ADAMTSL5 ADAMTS1 ADAMTS6 CFP SSPOP ADAMTSL4	5.75e-10	111	39	8	M27416
Pathway	REACTOME_DISEASES_OF_GLYCOSYLATION	ADAMTS10 THBS1 ADAMTSL5 ADAMTS1 ADAMTS6 CFP SSPOP ADAMTSL4	4.34e-09	143	39	8	M27275
Pathway	REACTOME_DISEASES_OF_METABOLISM	ADAMTS10 THBS1 ADAMTSL5 ADAMTS1 ADAMTS6 CFP SSPOP ADAMTSL4	3.35e-07	250	39	8	M27554
Pathway	REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK	ARHGEF7 ARHGEF4 ARHGEF6	5.72e-04	59	39	3	M11215
Pathway	REACTOME_CDC42_GTPASE_CYCLE	ARHGEF7 ARHGEF4 GMIP ARHGEF6	8.57e-04	155	39	4	M41808
Pathway	WP_NCRNAS_INVOLVED_IN_STAT3_SIGNALING_IN_HEPATOCELLULAR_CARCINOMA	IL11RA IL6R	9.88e-04	17	39	2	M39512
Pathway	REACTOME_CELL_DEATH_SIGNALLING_VIA_NRAGE_NRIF_AND_NADE	ARHGEF7 ARHGEF4 ARHGEF6	1.20e-03	76	39	3	M19832
Pathway	REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION	THBS1 ADAMTS1 LAMC3 KLKB1 CAPN11	1.34e-03	300	39	5	M610
Pathway	REACTOME_G_ALPHA_12_13_SIGNALLING_EVENTS	ARHGEF7 ARHGEF4 ARHGEF6	1.39e-03	80	39	3	M800
Pubmed	O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation.	ADAMTS10 THBS1 CILP2 ADAMTSL5 ADAMTS1 ADAMTS6 CFP POU5F1B SSPOP ADAMTSL4	4.64e-17	75	57	10	20637190
Pubmed	Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.	ROBO4 THBS1 FCGBP CFP IHH KLKB1 ADAMTSL4	2.14e-07	257	57	7	16335952
Pubmed	ADAMTS1 mediates the release of antiangiogenic polypeptides from TSP1 and 2.	THBS1 ADAMTS1	2.64e-06	2	57	2	17082774
Pubmed	Modular organization of Interleukin-6 and Interleukin-11 α-receptors.	IL11RA IL6R	2.64e-06	2	57	2	26551279
Pubmed	ADAMTS-10 and -6 differentially regulate cell-cell junctions and focal adhesions.	ADAMTS10 ADAMTS6	2.64e-06	2	57	2	27779234
Pubmed	ADAMTS1 alters blood vessel morphology and TSP1 levels in LNCaP and LNCaP-19 prostate tumors.	THBS1 ADAMTS1	2.64e-06	2	57	2	20546609
Pubmed	Novel ADAMTSL4 gene mutations in Chinese patients with isolated ectopia lentis.	THBS1 ADAMTSL4	2.64e-06	2	57	2	35042684
Pubmed	The ADAMTS (A Disintegrin and Metalloproteinase with Thrombospondin motifs) family.	ADAMTS1 ADAMTS6	7.91e-06	3	57	2	26025392
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	TINAGL1 GRAMD2A MYOF PWWP2B ADAMTSL5 APEH LAMC3 ARHGEF4 ADGRA2 PRRT4	1.12e-05	1105	57	10	35748872
Pubmed	PAK kinases are directly coupled to the PIX family of nucleotide exchange factors.	ARHGEF7 ARHGEF6	1.58e-05	4	57	2	9659915
Pubmed	Novel regulatory mechanisms for the Dbl family guanine nucleotide exchange factor Cool-2/alpha-Pix.	ARHGEF7 ARHGEF6	1.58e-05	4	57	2	15306850
Pubmed	A tyrosine-phosphorylated protein that binds to an important regulatory region on the cool family of p21-activated kinase-binding proteins.	ARHGEF7 ARHGEF6	1.58e-05	4	57	2	10428811
Pubmed	The Cool-2/alpha-Pix protein mediates a Cdc42-Rac signaling cascade.	ARHGEF7 ARHGEF6	1.58e-05	4	57	2	15649357
Pubmed	Expanding functions of GIT Arf GTPase-activating proteins, PIX Rho guanine nucleotide exchange factors and GIT-PIX complexes.	ARHGEF7 ARHGEF6	1.58e-05	4	57	2	27182061
Pubmed	Interaction of alphaPIX (ARHGEF6) with beta-parvin (PARVB) suggests an involvement of alphaPIX in integrin-mediated signaling.	ARHGEF7 ARHGEF6	1.58e-05	4	57	2	12499396
Pubmed	The Cbl proteins are binding partners for the Cool/Pix family of p21-activated kinase-binding proteins.	ARHGEF7 ARHGEF6	1.58e-05	4	57	2	12935897
Pubmed	An unusual peptide deformylase features in the human mitochondrial N-terminal methionine excision pathway.	METAP1 PDF	1.58e-05	4	57	2	14532271
Pubmed	Interactions between lysyl oxidases and ADAMTS proteins suggest a novel crosstalk between two extracellular matrix families.	ADAMTS10 ADAMTSL4	2.63e-05	5	57	2	29758265
Pubmed	Genetic Intersection of Tsix and Hedgehog Signaling during the Initiation of X-Chromosome Inactivation.	POU5F1B IHH	2.63e-05	5	57	2	29107559
Pubmed	Paxillin-dependent paxillin kinase linker and p21-activated kinase localization to focal adhesions involves a multistep activation pathway.	ARHGEF7 ARHGEF6	2.63e-05	5	57	2	12006652
Pubmed	The p21-activated kinase PAK is negatively regulated by POPX1 and POPX2, a pair of serine/threonine phosphatases of the PP2C family.	ARHGEF7 ARHGEF6	2.63e-05	5	57	2	11864573
Pubmed	The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.	TINAGL1 ROBO4 CDH24 POGLUT1 PRSS55 VMO1 MAMDC4 ADAMTSL4 NXPH4	3.00e-05	985	57	9	12975309
Pubmed	Interactome and Proteome Dynamics Uncover Immune Modulatory Associations of the Pathogen Sensing Factor cGAS.	MYOF THBS1 POGLUT1 TRIOBP HSPB1	3.68e-05	228	57	5	30471916
Pubmed	The X-linked lymphoproliferative disease gene product SAP associates with PAK-interacting exchange factor and participates in T cell activation.	ARHGEF7 ARHGEF6	5.51e-05	7	57	2	16983070
Pubmed	The GIT family of ADP-ribosylation factor GTPase-activating proteins. Functional diversity of GIT2 through alternative splicing.	ARHGEF7 ARHGEF6	5.51e-05	7	57	2	10896954
Pubmed	N-α-acetyltransferase 10 protein suppresses cancer cell metastasis by binding PIX proteins and inhibiting Cdc42/Rac1 activity.	ARHGEF7 ARHGEF6	5.51e-05	7	57	2	21295525
Pubmed	In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.	ROBO4 MYOF THBS1 CILP2 FCGBP APEH VMO1 KLKB1 HSPB1	5.70e-05	1070	57	9	23533145
Pubmed	Affixin activates Rac1 via betaPIX in C2C12 myoblast.	ARHGEF7 ARHGEF6	7.34e-05	8	57	2	18325335
Pubmed	ADAMTS: a novel family of extracellular matrix proteases.	ADAMTS10 ADAMTS6	1.18e-04	10	57	2	11167130
Pubmed	GPR124, an orphan G protein-coupled receptor, is required for CNS-specific vascularization and establishment of the blood-brain barrier.	ROBO4 THBS1 ADGRA2	1.27e-04	59	57	3	21421844
Pubmed	Loci at chromosomes 13, 19 and 20 influence age at natural menopause.	ARHGEF7 ADGRA2	1.44e-04	11	57	2	19448619
Pubmed	Proteomics analysis of cardiac extracellular matrix remodeling in a porcine model of ischemia/reperfusion injury.	TINAGL1 THBS1 SSPOP	1.62e-04	64	57	3	22261194
Pubmed	Insights on ADAMTS proteases and ADAMTS-like proteins from mammalian genetics.	ADAMTS10 ADAMTS1	1.72e-04	12	57	2	25770910
Pubmed	ADAMTS2 promotes radial migration by activating TGF-β signaling in the developing neocortex.	ADAMTS10 ADAMTS1	2.73e-04	15	57	2	38871984
Pubmed	Transcriptome-based systematic identification of extracellular matrix proteins.	THBS1 LAMC3 ADAMTSL4	3.02e-04	79	57	3	18757743
Pubmed	ADAM-TS5, ADAM-TS6, and ADAM-TS7, novel members of a new family of zinc metalloproteases. General features and genomic distribution of the ADAM-TS family.	ADAMTS1 ADAMTS6	3.53e-04	17	57	2	10464288
Pubmed	Pharmacogenomic study of side-effects for antidepressant treatment options in STAR*D.	C9orf50 POU5F1B	3.53e-04	17	57	2	22041458
Pubmed	The transcription factor hepatocyte nuclear factor-6 controls the development of pancreatic ducts in the mouse.	PKHD1 SLC4A4	3.53e-04	17	57	2	16472605
Pubmed	Comprehensive proteomic characterization of stem cell-derived extracellular matrices.	THBS1 ADAMTS1 ADAMTSL4	3.88e-04	86	57	3	28327460
Pubmed	Proteolysis of fibrillin-2 microfibrils is essential for normal skeletal development.	ADAMTS10 ADAMTS6	3.97e-04	18	57	2	35503090
Pubmed	Dynamic and coordinated expression profile of dbl-family guanine nucleotide exchange factors in the developing mouse brain.	ARHGEF7 ARHGEF6	3.97e-04	18	57	2	12799088
Pubmed	The nuclear import of the small GTPase Rac1 is mediated by the direct interaction with karyopherin alpha2.	ARHGEF7 ARHGEF6	3.97e-04	18	57	2	19961560
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	MYOF TRIOBP ARHGEF4 ADGRA2	5.15e-04	225	57	4	12168954
Pubmed	Embryonic cholecystitis and defective gallbladder contraction in the Sox17-haploinsufficient mouse model of biliary atresia.	PKHD1 IHH	5.97e-04	22	57	2	28432216
Pubmed	Proteomics characterization of extracellular space components in the human aorta.	TINAGL1 THBS1 CFP	6.21e-04	101	57	3	20551380
Pubmed	Embryonic lethality in mice lacking Trim59 due to impaired gastrulation development.	TRIOBP POU5F1B	6.53e-04	23	57	2	29467473
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	PDE3B POGLUT1 PWWP2B EEPD1 TRIOBP ARHGEF4 SSPOP NXPH4 IL6R	6.64e-04	1489	57	9	28611215
Pubmed	Rhox8 homeobox gene ablation leads to rete testis abnormality and male subfertility in mice†.	POU5F1B SLC4A4	7.12e-04	24	57	2	37471646
Pubmed	Regulation of cell polarity in the cartilage growth plate and perichondrium of metacarpal elements by HOXD13 and WNT5A.	THBS1 IHH	7.12e-04	24	57	2	24161848
Pubmed	Identification of preferred protein interactions by phage-display of the human Src homology-3 proteome.	ARHGEF7 ARHGEF6	7.73e-04	25	57	2	16374509
Pubmed	Platelet proteome analysis reveals integrin-dependent aggregation defects in patients with myelodysplastic syndromes.	METAP1 HSPB1	8.36e-04	26	57	2	23382103
Pubmed	Large-scale interaction profiling of PDZ domains through proteomic peptide-phage display using human and viral phage peptidomes.	ARHGEF7 ADGRA2	9.02e-04	27	57	2	24550280
Pubmed	EGFL7 is expressed in bone microenvironment and promotes angiogenesis via ERK, STAT3, and integrin signaling cascades.	IL11RA IHH	1.04e-03	29	57	2	24909139
Pubmed	Uterine Rbpj is required for embryonic-uterine orientation and decidual remodeling via Notch pathway-independent and -dependent mechanisms.	IL11RA IHH	1.04e-03	29	57	2	24971735
Pubmed	Large-scale proteomics and phosphoproteomics of urinary exosomes.	MYOF THBS1 FCGBP PKHD1 SLC4A4 VMO1 HSPB1	1.32e-03	1016	57	7	19056867
Pubmed	Expression pattern of LRR and Ig domain-containing protein (LRRIG protein) in the early mouse embryo.	NTRK1 ADGRA2	1.43e-03	34	57	2	18848646
Pubmed	Gene content of the 750-kb critical region for mouse embryonic ectoderm lethal tcl-w5.	ADAMTS10 TAPBP	1.60e-03	36	57	2	15112104
Interaction	PRG2 interactions	TINAGL1 THBS1 CILP2 POGLUT1 ADAMTS1 LAMC3 TAPBP NXPH4	7.40e-07	285	53	8	int:PRG2
GeneFamily	ADAM metallopeptidases with thrombospondin type 1 motif	ADAMTS10 ADAMTS1 ADAMTS6	8.78e-06	19	39	3	50
GeneFamily	Immunoglobulin like domain containing	IL11RA CILP2 NTRK1 ADGRA2 IL6R	5.64e-05	193	39	5	594
GeneFamily	ADAMTS like	ADAMTSL5 ADAMTSL4	9.46e-05	7	39	2	947
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	ARHGEF7 ARHGEF4 ARHGEF6	3.87e-04	66	39	3	722
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	ARHGEF7 TRIOBP ARHGEF4 ARHGEF6	9.85e-04	206	39	4	682
GeneFamily	CD molecules\|I-set domain containing\|Immunoglobulin like domain containing\|Interleukin receptors\|TIR domain containing	IL11RA IL6R	3.70e-03	42	39	2	602
Coexpression	NABA_MATRISOME	TINAGL1 ADAMTS10 THBS1 CILP2 ADAMTSL5 ADAMTS1 ADAMTS6 MMP21 LAMC3 IHH SSPOP ADAMTSL4	1.40e-06	1008	57	12	MM17056
Coexpression	NABA_MATRISOME	TINAGL1 ADAMTS10 THBS1 CILP2 ADAMTSL5 ADAMTS1 ADAMTS6 MMP21 LAMC3 IHH SSPOP ADAMTSL4	1.69e-06	1026	57	12	M5889
Coexpression	NABA_ECM_REGULATORS	ADAMTS10 ADAMTSL5 ADAMTS1 ADAMTS6 MMP21 ADAMTSL4	1.30e-05	238	57	6	M3468
Coexpression	NABA_ECM_REGULATORS	ADAMTS10 ADAMTSL5 ADAMTS1 ADAMTS6 MMP21 ADAMTSL4	1.42e-05	242	57	6	MM17062
Coexpression	NABA_ECM_GLYCOPROTEINS	TINAGL1 THBS1 CILP2 LAMC3 SSPOP	6.00e-05	191	57	5	MM17059
Coexpression	NABA_ECM_GLYCOPROTEINS	TINAGL1 THBS1 CILP2 LAMC3 SSPOP	6.78e-05	196	57	5	M3008
Coexpression	GSE2770_IL12_AND_TGFB_VS_IL4_TREATED_ACT_CD4_TCELL_48H_UP	POGLUT1 APEH CFP TAPBP IL6R	7.46e-05	200	57	5	M6035
ToppCell	wk_15-18-Epithelial-Distal_epithelial_progenitor-epi-tip_intermediate\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	PWWP2B PKHD1 POU5F1B IHH SLC4A4 MAMDC4	1.36e-07	185	57	6	636505a3d96f75d951ab42bcf8af6ae07abc732d
ToppCell	(01)_IL1RL1+\|World / shred by cell type by condition	TINAGL1 THBS1 ADAMTSL5 ADAMTS1 ADAMTSL4 HSPB1	2.15e-07	200	57	6	501420901bf3ec1b050e0d14596a9f9f3fdfc928
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Otx2-Inhibitory_Neuron.Gad1Gad2.Otx2-Chrna3_(SN/VTA_(dorsal_SNr))-\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	CDH24 CILP2 NTRK1 KLRG2	2.63e-06	75	57	4	730a08f846a155d2c892259f2c610081d40fc2c8
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Otx2\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	CDH24 CILP2 NTRK1 KLRG2	2.63e-06	75	57	4	f0185de0ce497997df1027a51c099d91294bba07
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Otx2-Inhibitory_Neuron.Gad1Gad2.Otx2-Chrna3_(SN/VTA_(dorsal_SNr))\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	CDH24 CILP2 NTRK1 KLRG2	2.63e-06	75	57	4	59fe56388697037b335f334cb3461f15c7b3b506
ToppCell	3'-Child04-06-SmallIntestine-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ARHGEF7 TRIOBP ADGRA2 KLKB1 HSPB1	2.83e-06	173	57	5	85083b9ce20351dd69aa2327ad087b848b4307ff
ToppCell	droplet-Pancreas-Exocrine-18m-Endothelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ROBO4 THBS1 ADAMTS1 ADGRA2 PRRT4	3.62e-06	182	57	5	3b4dbf61ca0fe50efe05449815630e301cb76630
ToppCell	droplet-Pancreas-Exocrine-18m-Endothelial-endothelial_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ROBO4 THBS1 ADAMTS1 ADGRA2 PRRT4	3.62e-06	182	57	5	ab5761bf9af439231cd0f487b6467e372672a517
ToppCell	facs-Lung-nan-3m-Endothelial-Artery_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TINAGL1 MYOF MMP21 SLC4A4 PRRT4	3.72e-06	183	57	5	12e876d6205af8aad74265c668b5e95b9e7487f3
ToppCell	Substantia_nigra-Endothelial\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	TINAGL1 MYOF LAMC3 ADGRA2 HSPB1	4.35e-06	189	57	5	bef8234bd9c4d6e3cdef0791d8066b39ba56ebba
ToppCell	droplet-Pancreas-Exocrine-18m-Endothelial-nan\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYOF THBS1 ADAMTS1 ADGRA2 PRRT4	4.70e-06	192	57	5	a42aed9e563f5f4af029b8804c104f11ad227a8f
ToppCell	droplet-Lung-LUNG-1m-Endothelial-Capillary_Aerocyte_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ROBO4 PWWP2B ADAMTSL5 PRRT4 HSPB1	4.70e-06	192	57	5	f094ac378e635cf5820e8a8b7a0152073a51ceae
ToppCell	droplet-Lung-nan-18m-Endothelial-Capillary_Aerocyte_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ROBO4 PWWP2B LAMC3 PRRT4 HSPB1	4.94e-06	194	57	5	f35f03412b596b6b570b377ba1a607409d984bb1
ToppCell	3'-GW_trimst-1-SmallIntestine-Mesenchymal-myocytic-SMC_(PART1/CAPN3+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TINAGL1 MYOF ADAMTS1 ADAMTS6 HSPB1	5.07e-06	195	57	5	bd7526dd80a60ff7bc866e4f5a0e8acdbc10d191
ToppCell	10x_3'_v3-bone_marrow_(10x_3'_v3)-myeloid-myeloid_macrophage\|bone_marrow_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	MYOF THBS1 CFP VMO1 ADAMTSL4	5.07e-06	195	57	5	4e9513a7ea69fa9fc8e9ff2da8ef3f44e8fdc70d
ToppCell	10x_3'_v3-bone_marrow_(10x_3'_v3)-myeloid-myeloid_macrophage-macrophage\|bone_marrow_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	MYOF THBS1 CFP VMO1 ADAMTSL4	5.07e-06	195	57	5	a25a342380e258b784227f7298f609ccaa1f9ce7
ToppCell	Enterocyte-C_05\|Enterocyte / shred on cell type and cluster	MYOF FCGBP SLC4A4 APOBR HSPB1	5.19e-06	196	57	5	c307e5a70186567c62da938caa21749dc0e929d0
ToppCell	Tracheal-NucSeq-Endothelial-Endothelia_vascular\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ROBO4 ADAMTS1 ADAMTS6 EEPD1 CAPN11	5.46e-06	198	57	5	f7aa809040fa9f5782b92eec1f289d690eb5c7bd
ToppCell	Caecum-(6)_Macrophage-(61)_LYVE1_Macrophage\|Caecum / shred on region, Cell_type, and subtype	MYOF FCGBP CFP SSPOP ADAMTSL4	5.46e-06	198	57	5	e684c3934c163aef4d284b69435832d2c9614f2a
ToppCell	Caecum-Macrophage-LYVE1_Macrophage\|Caecum / Region, Cell class and subclass	MYOF FCGBP CFP SSPOP ADAMTSL4	5.46e-06	198	57	5	a92c0cacb775aca6bbb302bd9e22c081a112a44d
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Perivascular_fibroblast\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NTRK1 MMP21 LAMC3 ADGRA2 KLKB1	5.59e-06	199	57	5	dfc5c7a4a093baa7158dd8d4d29a870d9c469a3f
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Perivascular_fibroblast-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NTRK1 MMP21 LAMC3 ADGRA2 KLKB1	5.59e-06	199	57	5	c1760581c34b81d1d92c67500a1c8944e9cc6dad
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW19-Macroglial\|GW19 / Sample Type, Dataset, Time_group, and Cell type.	ADAMTS6 EEPD1 ARHGEF4 SLC4A4 HSPB1	5.73e-06	200	57	5	3a954d9d542e52c9b181f0850a09b1bff0a0c82d
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Sema3e_Kank4\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ADAMTSL5 KLRG2 C9orf50 ARHGEF6	1.59e-05	118	57	4	d7dcffc0476a6e471debd83904a6569c6f27a594
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Reln_Itm2a\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ADAMTSL5 C9orf50 SLC4A4 ARHGEF6	3.48e-05	144	57	4	0bbe670454846cf9bc7464ae4e91488415c4111d
ToppCell	facs-Skin-Anagen-24m-Epithelial-basal_cell_of_epidermis\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FCGBP PRSS55 NXPH4 IL6R	4.53e-05	154	57	4	89a94a36dfd3d75e411038f04adaf0bbab17db45
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_TBC1D26\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MYOF CDH24 LAMC3 NXPH4	5.00e-05	158	57	4	3d6295fe25e3b1fb4b6e83704c5bdbf86dc639b3
ToppCell	droplet-Kidney-KIDNEY-1m-Lymphocytic-lymphocyte\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CILP2 EEPD1 CFP MAMDC4	5.13e-05	159	57	4	3bab00f8fb7d9232538e50f83dd0fd70ddd16819
ToppCell	droplet-Kidney-KIDNEY-1m-Lymphocytic-CD45\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CILP2 EEPD1 CFP MAMDC4	5.25e-05	160	57	4	5bec867def73fa8531f8dad611679f4b44f573bd
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell_prolif\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	IL11RA ROBO4 ADAMTS6 ADGRA2	5.65e-05	163	57	4	1feb4ef7b8abcfca9a72c8d13c40548de79e7db2
ToppCell	NS-moderate-d_16-33-Myeloid-Mast_cell\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	ROBO4 AQP10 NTRK1 ARHGEF6	5.78e-05	164	57	4	35c673380f75cb4bfe080089bc723c4373bcc7a5
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Reln_Tac1\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ADAMTSL5 C9orf50 SLC4A4 ARHGEF6	5.92e-05	165	57	4	d8df50f5a3b646e8ea13739fdc65ce6f39b4d4d2
ToppCell	Mild-Myeloid-Mast\|Mild / Condition, Lineage, Cell class and cell subclass	TINAGL1 AQP10 NTRK1 ARHGEF6	5.92e-05	165	57	4	5fa9552c37890c5cc7e672a47038aebba2413cb4
ToppCell	Mild-Myeloid-Mast-\|Mild / Condition, Lineage, Cell class and cell subclass	TINAGL1 AQP10 NTRK1 ARHGEF6	5.92e-05	165	57	4	93d3909a0f5f43d473d5005c842d7d73e25eceed
ToppCell	368C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	GRAMD2A PDF ARHGEF7 MAMDC4	6.35e-05	168	57	4	3fb79aaa858057c82645a90bd139fc4f096323c7
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	EEPD1 LAMC3 ADGRA2 PRRT4	6.35e-05	168	57	4	d19a115365c5415e51c039718d7669de788fcf33
ToppCell	368C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	GRAMD2A PDF ARHGEF7 MAMDC4	6.50e-05	169	57	4	0589f39d8e9468e42d25d30ff70bb7cb8b921628
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Reln_Itm2a\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ADAMTSL5 ADAMTS1 C9orf50	6.59e-05	61	57	3	59471f0b5235dcf9420d14221a9b4d75a8ddf78e
ToppCell	droplet-Pancreas-Exocrine-18m-Epithelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TINAGL1 MYOF PKHD1 LAMC3	6.80e-05	171	57	4	5447b78148f7bccb727e2fc108589b2af02a5d31
ToppCell	droplet-Pancreas-Exocrine-18m-Epithelial-pancreatic_ductal_cel\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TINAGL1 MYOF PKHD1 LAMC3	6.96e-05	172	57	4	a7eee0a30d2fe20c865a07b9004c6a821a72c0c4
ToppCell	droplet-Pancreas-Exocrine-18m-Epithelial-pancreatic_ductal_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TINAGL1 MYOF PKHD1 LAMC3	6.96e-05	172	57	4	0a9fe2cd28203970295a1288078c66eadac1c9ed
ToppCell	3'-Child09-12-SmallIntestine-Hematopoietic-T_cells-Th1\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CCSAP NTRK1 PKHD1 APEH	6.96e-05	172	57	4	c0c9a3f5b5fb942b049bc159fd9f21b5b706edd2
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.4\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FCGBP RNF225 VMO1 HSPB1	7.11e-05	173	57	4	176b956e71d98e8275d698b39437fc326e5fe449
ToppCell	facs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-1\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MYOF ADAMTS1 NTRK1 TRIOBP	7.27e-05	174	57	4	1d157f7a919c8246e83d8060d2a0017c6c781ef3
ToppCell	moderate-Myeloid-Mast_cell\|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	ROBO4 AQP10 NTRK1 ARHGEF6	7.44e-05	175	57	4	bbd2971bc6d69e507f90a637834d0936c205c590
ToppCell	facs-Skin-nan-24m-Epithelial-basal_cell_of_epidermis\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS1 FCGBP NXPH4 IL6R	7.44e-05	175	57	4	21542be95059983d2c8bdf01ec711fdbf1ec1f62
ToppCell	3'-Child04-06-SmallIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TINAGL1 ADAMTS10 NTRK1 ADGRA2	7.60e-05	176	57	4	90f36f10c6ed440a0ca549f23219398853f1fbc3
ToppCell	facs-Brain_Myeloid-Striatum-24m-Myeloid-macrophage\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTS10 KLRG2 CFP ADGRA2	7.77e-05	177	57	4	f6b9d91d46830d0d207b0abd4ee5a4942fd99774
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-DC-DC3-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	POGLUT1 LRRC61 CFP VMO1	7.77e-05	177	57	4	d34b086a5931d7f1737a504952d51c47693e91a8
ToppCell	droplet-Heart-4Chambers-18m-Endothelial-endothelial_cell_of_coronary_artery\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TINAGL1 ROBO4 EEPD1 HSPB1	7.94e-05	178	57	4	93ce73f8bcec63ebf86fabb546f88400e8f06465
ToppCell	Endothelial\|World / shred by cell class for turbinate	ROBO4 ADAMTS1 ADGRA2 ADAMTSL4	8.12e-05	179	57	4	052b2681974be00efb8503fa4e2c85d91d5ebd06
ToppCell	droplet-Mammary_Gland-nan-18m-Endothelial-nan\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TINAGL1 ROBO4 PRRT4 HSPB1	8.47e-05	181	57	4	2e15c46e8260bb04d8264478c19a707221996026
ToppCell	tumor_Lymph_Node_/_Brain-Myeloid_cells-Alveolar_Mac\|Myeloid_cells / Location, Cell class and cell subclass	VMO1 ADAMTSL4 HSPB1 CAPN11	8.66e-05	182	57	4	a035d45fd512bee8dac38eb387dbf39f5a8a1fed
ToppCell	droplet-Kidney-nan-3m-Endothelial-Pecam____kidney_capillary_endothelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ROBO4 ADAMTSL5 ADAMTS1 HSPB1	8.66e-05	182	57	4	f4a5f1c3a04c0566eb96607dab7a0d9a5ebc3fd1
ToppCell	tumor_Lung-Fibroblasts-Pericytes\|tumor_Lung / Location, Cell class and cell subclass	TINAGL1 ADAMTS1 LAMC3 ADGRA2	8.84e-05	183	57	4	a03dd563af9b15cb1f5de5732a229405a9f82d84
ToppCell	5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.1.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TINAGL1 ROBO4 CDH24 ADAMTS6	8.84e-05	183	57	4	ce8be9418b473ea94ec806edc7a2078cc30c1703
ToppCell	droplet-Heart-4Chambers-21m-Endothelial-endothelial_cell_of_coronary_artery\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TINAGL1 ROBO4 EEPD1 HSPB1	8.84e-05	183	57	4	29defb21458bc43d22ca5e4d08218db45aaa1add
ToppCell	3'-Pediatric_IBD-SmallIntestine-Hematopoietic-Myeloid-Lymphoid_DC\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	POGLUT1 CFP VMO1 IL6R	8.84e-05	183	57	4	9ca4954faaba50466c35121d6765895e955178aa
ToppCell	LPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MYOF ADAMTS1 LAMC3 SLC4A4	9.03e-05	184	57	4	327ff3ac8d2fecdd5d242bdc34f0dfdb1c59a68b
ToppCell	droplet-Mammary_Gland-nan-21m-Endothelial-nan\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TINAGL1 ROBO4 KLKB1 HSPB1	9.22e-05	185	57	4	62cfcb0e2a9e6718e6b200dfbb1a81eaead229b5
ToppCell	P15-Mesenchymal-mesenchymal_fibroblast\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	IL11RA EEPD1 IL6R HSPB1	9.22e-05	185	57	4	46460e74cc613df9043f5404e7342aa13cc34873
ToppCell	droplet-Heart-nan-24m-Endothelial-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TINAGL1 ROBO4 EEPD1 HSPB1	9.22e-05	185	57	4	11a44006950f6ccade86a85d5f06696d2036ffde
ToppCell	droplet-Heart-nan-24m-Endothelial-endothelial_cell_of_coronary_artery\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TINAGL1 ROBO4 EEPD1 HSPB1	9.41e-05	186	57	4	8b316bfed39b91c15d5ae28d9261eb057f113796
ToppCell	Thalamus-Endothelial\|Thalamus / BrainAtlas - Mouse McCarroll V32	TINAGL1 MYOF ADGRA2 HSPB1	9.41e-05	186	57	4	dcc6e4417c4123d5ca6b96fa8ca4874626aaebdb
ToppCell	P15-Mesenchymal-mesenchymal_fibroblast-alveolar_fibroblast_Wnt2-pa\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	IL11RA EEPD1 IL6R HSPB1	9.41e-05	186	57	4	88e6246172d816806a498a5c1f38e699f2f5d7c2
ToppCell	Fetal_29-31_weeks-Mesenchymal-pericyte_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	TINAGL1 MYOF LAMC3 ADGRA2	9.61e-05	187	57	4	a2bf958ea59c359a265bfa437d59315e1920cdd4
ToppCell	P15-Mesenchymal\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	IL11RA THBS1 IL6R HSPB1	9.81e-05	188	57	4	f1ba0b661621a65c91432e62ba73531bdf18e7c1
ToppCell	Frontal_cortex-Endothelial\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	TINAGL1 MYOF ADGRA2 HSPB1	9.81e-05	188	57	4	a43392dbd10fc7dbfb31be39b8af8a7ea121c894
ToppCell	ASK454-Epithelial-Type_1\|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq	TINAGL1 GRAMD2A KLRG2 ARHGEF4	9.81e-05	188	57	4	13f8ce8f24ac7d7ed87f4ae3b8f4096de29383c2
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_ductal_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TINAGL1 ADAMTS1 PKHD1 ADAMTSL4	9.81e-05	188	57	4	842982de2197770f999a70083ed9fca40ac22d79
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_ductal_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TINAGL1 ADAMTS1 PKHD1 ADAMTSL4	9.81e-05	188	57	4	a0815eaf68eedd6e5ec4af520df80a6ab4eb0864
ToppCell	Entopeduncular-Endothelial\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	TINAGL1 ADGRA2 IL6R HSPB1	9.81e-05	188	57	4	94774652fd42bad5012356672ffac8b6d2c22d37
ToppCell	Endothelial-A-IPF_01\|World / lung cells shred on cell class, cell subclass, sample id	TINAGL1 ROBO4 ADAMTS1 ADGRA2	1.00e-04	189	57	4	04b565855f58ca0f343904d04be657b66e109076
ToppCell	facs-Skin-Skin_Anagen-18m-Epithelial-Basal_IFE\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS1 FCGBP NXPH4 IL6R	1.00e-04	189	57	4	1cfc1fe27c4b57b4e52700fa8f679ce172cee5a9
ToppCell	Striatum-Endothelial\|Striatum / BrainAtlas - Mouse McCarroll V32	TINAGL1 LAMC3 ADGRA2 HSPB1	1.00e-04	189	57	4	95ee3b6d7fbbfcf91c780dfcd0926acec05f0a2d
ToppCell	3'_v3-GI_small-bowel-Myeloid_Monocytic-Classical_monocytes\|GI_small-bowel / Manually curated celltypes from each tissue	MYOF THBS1 CFP IL6R	1.00e-04	189	57	4	74a5e61cd820f2495dde40e766c771a31d8c4e7d
ToppCell	facs-Lung-3m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_aerocyte_endothelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ROBO4 ADAMTSL5 PRRT4 HSPB1	1.02e-04	190	57	4	52213cd2a6a20772d4f49ba9ac0407abafa528db
ToppCell	facs-Heart-RV-3m-Endothelial-endothelial_cell_of_coronary_artery\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TINAGL1 ROBO4 EEPD1 HSPB1	1.02e-04	190	57	4	89d1d686cc683206534e2157554d7d0df5d53497
ToppCell	facs-MAT-Fat-18m-Endothelial\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TINAGL1 ROBO4 IHH HSPB1	1.02e-04	190	57	4	34e56c5e7ea6a8f227dbaefe73cbb8818d18b523
ToppCell	droplet-Kidney-KIDNEY-30m-Epithelial-podocyte\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TINAGL1 MYOF THBS1 ADAMTS1	1.02e-04	190	57	4	050d6e0546954675b6adbfecb67854b1e09739d1
ToppCell	facs-MAT-Fat-18m-Endothelial-nan\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TINAGL1 ROBO4 IHH HSPB1	1.02e-04	190	57	4	14cdb660ad3aabcf49572173e7628d8b99dcbe6f
ToppCell	facs-Heart-RV-3m-Endothelial-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TINAGL1 ROBO4 EEPD1 HSPB1	1.02e-04	190	57	4	65ba6c4f4a2905c0bf4ff99518ae49e3dfd5e640
ToppCell	facs-MAT-Fat-18m-Endothelial-endothelial_cell\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TINAGL1 ROBO4 IHH HSPB1	1.02e-04	190	57	4	9aaa48f3aad813c87a45efdbb67d255c94f6e6a4
ToppCell	Endothelial-A-Myositis-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	TINAGL1 ROBO4 ADAMTS1 ADAMTS6	1.04e-04	191	57	4	f702dfe88a9b04091dae87df61b2b4f43525f86a
ToppCell	facs-Thymus-Epithelium-3m-Endothelial\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TINAGL1 ROBO4 KLRG2 HSPB1	1.04e-04	191	57	4	6676ef9aeb890668cb69e67865404061b8467c25
ToppCell	facs-Thymus-Epithelium-3m-Endothelial-endothelial_cell\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TINAGL1 ROBO4 KLRG2 HSPB1	1.04e-04	191	57	4	a157cee0fbc9dce64308128c3578e7327fa178b7
ToppCell	facs-Thymus-Epithelium-3m-Endothelial-endothelial_cell\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TINAGL1 ROBO4 KLRG2 HSPB1	1.04e-04	191	57	4	d2311a5b0cf186839000f9f272b6fbc2270ddb44
ToppCell	human_hepatoblastoma-Hepatic_Stellate_cells\|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)	MYOF ADAMTS1 LAMC3 ADGRA2	1.04e-04	191	57	4	78c3c2fdb68c3407f2436f90e1e6a780bbf8b79e
ToppCell	facs-Heart-RV-3m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TINAGL1 ROBO4 EEPD1 HSPB1	1.04e-04	191	57	4	84ebb9f8e975acc88aa600c08a8aa791256948a6
ToppCell	facs-Trachea-3m-Mesenchymal-fibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	IL11RA ADAMTSL5 ADAMTS1 LRRC61	1.06e-04	192	57	4	321850b0f881420c2d57d3e825e365c82fa511ab
ToppCell	droplet-Lung-1m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_aerocyte_endothelial_cell\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ROBO4 ADAMTSL5 PRRT4 HSPB1	1.06e-04	192	57	4	ff435141329e3e29fa9b08a4d5b2f55074e7f9ab
ToppCell	Hippocampus-Endothelial\|Hippocampus / BrainAtlas - Mouse McCarroll V32	TINAGL1 LAMC3 ADGRA2 HSPB1	1.06e-04	192	57	4	36deadab892d3e639a71f33697bb2d3cbbaa5372
ToppCell	facs-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	IL11RA ADAMTSL5 ADAMTS1 LRRC61	1.06e-04	192	57	4	cf2765d8bc074f7f9ee864eae632a3b705175842
ToppCell	Monocytes-Inflammatory_CD16+_macrophages\|World / Immune cells in Kidney/Urine in Lupus Nephritis	MYOF CFP VMO1 ADAMTSL4	1.06e-04	192	57	4	4be5c2c946337cd3e710137726358adca563f146
ToppCell	facs-BAT-Fat-3m-Endothelial-nan\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TINAGL1 ROBO4 ADAMTS1 HSPB1	1.09e-04	193	57	4	e340064cd146deac03f2d0fd43e2e218bb6057c9
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TINAGL1 THBS1 PKHD1 KLRG2	1.09e-04	193	57	4	ffa1932da2979d7b63dbac32eb5788346a3f5b2a
ToppCell	droplet-Lung-nan-21m-Endothelial-Capillary_Aerocyte_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ROBO4 ADAMTSL5 PRRT4 HSPB1	1.09e-04	193	57	4	ffdcbc5caff7fd4cc2e83dd21a05d43b0593d542
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage-macrophage,_alveolar-Macro_c6-VCAN\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	MYOF THBS1 CFP ADAMTSL4	1.09e-04	193	57	4	52f5b0fbb8ca706206c65e7edbb1ddbd380aebae
ToppCell	facs-MAT-Fat-3m-Endothelial\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TINAGL1 ROBO4 PRRT4 HSPB1	1.09e-04	193	57	4	b32533afeff1905e188becaa09079e9699722e4b
ToppCell	facs-MAT-Fat-3m-Endothelial-nan\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TINAGL1 ROBO4 PRRT4 HSPB1	1.09e-04	193	57	4	2ff573ba2c74583ed1cb071a3bbc01bb71117e5f
Disease	interleukin 6 receptor subunit alpha measurement	AQP10 IL6R	2.35e-04	13	52	2	EFO_0008187
Disease	arginine measurement	TINAGL1 KLKB1	7.53e-04	23	52	2	EFO_0020990
Disease	L-arginine measurement	TINAGL1 KLKB1	1.04e-03	27	52	2	EFO_0006524
Disease	Papillary Renal Cell Carcinoma	VMO1 IL6R HSPB1	1.51e-03	128	52	3	C1306837
Disease	Renal Cell Carcinoma	VMO1 IL6R HSPB1	1.51e-03	128	52	3	C0007134
Disease	Sarcomatoid Renal Cell Carcinoma	VMO1 IL6R HSPB1	1.51e-03	128	52	3	C1266043
Disease	Chromophobe Renal Cell Carcinoma	VMO1 IL6R HSPB1	1.51e-03	128	52	3	C1266042
Disease	Collecting Duct Carcinoma of the Kidney	VMO1 IL6R HSPB1	1.51e-03	128	52	3	C1266044

Protein segments in the cluster

Peptide	Gene	Start	Entry
SEGLAWGPWAQPWAP	nan	166	Q6ZR03
TLTLWQSTGPWGPGW	MAMDC4	166	Q6UXC1
DWRIPGGGAAWWPEG	C9orf50	51	Q5SZB4
GWWEGTLNGRTGWFP	ARHGEF6	196	Q15052
QGPEGVWGPWVQWAS	ADAMTSL4	41	Q6UY14
AWWSQEGPGEAGGWT	ADGRA2	711	Q96PE1
WWWGRVADGEGWFPA	ARHGEF4	231	Q9NR80
GPEVFSAGNGWWWVP	AQP10	231	Q96PS8
WWEGTLNGRTGWFPS	ARHGEF7	221	Q14155
PWLWDDWGPAGSSED	CCSAP	46	Q6IQ19
PWGRIEWNGAWSDSA	CAPN11	321	Q9UMQ6
EGLTNPWIPDNWSWG	EEPD1	511	Q7L9B9
PWIPDNWSWGGVASE	EEPD1	516	Q7L9B9
VDGAWGPWTPWGDCS	ADAMTS10	546	Q9H324
GTWPQSIDGGWGPWS	ADAMTS6	551	Q9UKP5
SIDGGWGPWSLWGEC	ADAMTS6	556	Q9UKP5
SDGLGVGRAWSWAWP	NXPH4	56	O95158
TPFHGSWGMWGPWGD	ADAMTS1	556	Q9UHI8
GPWGAEPGWVDPLTW	POU5F1B	21	Q06416
YPAWTFWEGGPAVWP	POGLUT1	161	Q8NBL1
AGTWSTWSPEAWGTP	IL11RA	301	Q14626
GWHSWAAGPGSLLAW	NTRK1	11	P04629
VWGPCWDPAWTLIGQ	KIAA0100	1096	Q14667
CEGGWQDETWPDGWT	METAP1	331	P53582
AQPWVEPGYWESWPS	LRRC61	196	Q9BV99
PWEDPGTGWRWQGTP	GMIP	401	Q9P107
ATELGWSWGPERGWV	CDH24	451	Q86UP0
GWSGVWAAWGPSPEG	MMP21	61	Q8N119
WWSWPWGDGDAGSAA	PDE3B	171	Q13370
EWSQWLGGSSWPGYV	HSPB1	41	P04792
MGGWSGWGPWEPCSV	CFP	136	P27918
PCPVDGEWDSWGEWS	CFP	311	P27918
WPLWAAVPWGGAAAV	PDF	11	Q9HBH1
SAQGPGEWTPWVSWT	ADAMTSL5	41	Q6ZMM2
GEWSEWSPEAMGTPW	IL6R	301	P08887
AWRGPQGWHWIDEAP	KLRG2	351	A4D1S0
SEGRHAWEVWWEGPL	FBXO45	151	P0C2W1
AWEVWWEGPLGTVAV	FBXO45	156	P0C2W1
SIPIWGGSWRAPGWD	FCGBP	1836	Q9Y6R7
GGSWRAPGWDPLCWD	FCGBP	1841	Q9Y6R7
IVGGTNSSWGEWPWQ	KLKB1	391	P03952
ASENGGRWAWPMPGW	GRAMD2A	256	Q8IUY3
GDIVWGKIHGFPWWP	PWWP2B	491	Q6NUJ5
AWGSWTPGEGVHWYP	IHH	371	Q14623
DVTWGWEHWGGILPQ	METTL26	86	Q96S19
WTAANSWGPAWGERG	TINAGL1	421	Q9GZM7
EEQGCGAWGPWSPWG	SSPOP	1691	A2VEC9
AEGEPTWSPWTPWSQ	SSPOP	3181	A2VEC9
PGVWSSWGPWEDCSV	SSPOP	3646	A2VEC9
TGRWWIVGSAWSGAP	NOM1	606	Q5C9Z4
IEVTSGGPWGDWAWP	VMO1	36	Q7Z5L0
WSLPETWQGVEEGWG	PKHD1	2736	P08F94
SWSSQEGGLGPGGWW	TRIOBP	1446	Q9H2D6
PWGHPEPTVSWWKDG	ROBO4	161	Q8WZ75
WAPGDAGVVFVGWWH	APEH	251	P13798
RAWGTWGPGAEPEDW	APOBR	261	Q0VD83
EASWGAWGPWGPCSG	CILP2	146	Q8IUL8
INGGWGPWSPWDICS	THBS1	491	P07996
TWGTEAGPGWAPWPR	RNF225	306	M0QZC1
WDDDEPWGPWTGNGT	TAPBP	241	O15533
PWGPWTGNGTFWLPT	TAPBP	246	O15533
MASAVWGSAPWWGPP	TMEM102	1	Q8N9M5
GGQSGLEGPWPWWAF	PRRT4	586	C9JH25
PGPATWRECWVAGWG	PRSS55	181	Q6UWB4
RGWFVPPFGENPWWV	SLC4A4	766	Q9Y6R1
WSGGAWPGSPGWRLA	nan	71	Q6ZPA2
WWARSVGGSEHPPQW	LAMC3	511	Q9Y6N6
PPKGWEWEGEWIVDP	MYOF	901	Q9NZM1