Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	uridylyltransferase activity	GALT TUT7	2.74e-04	7	73	2	GO:0070569
GeneOntologyMolecularFunction	aspartic-type endopeptidase activity	ERVK-19 ERVK-25 ERVK-24	3.33e-04	37	73	3	GO:0004190
GeneOntologyMolecularFunction	aspartic-type peptidase activity	ERVK-19 ERVK-25 ERVK-24	3.61e-04	38	73	3	GO:0070001
GeneOntologyMolecularFunction	transferase activity, transferring phosphorus-containing groups	CDK20 HIPK3 POLR1A GALT DSTYK TUT7 GNPTAB HIPK2 MAP3K9 MAPK11 EPHA8	5.72e-04	938	73	11	GO:0016772
GeneOntologyCellularComponent	stereocilium	MYO7A STRC USH2A STRCP1	9.44e-05	69	72	4	GO:0032420
GeneOntologyCellularComponent	stereocilium bundle	MYO7A STRC USH2A STRCP1	1.60e-04	79	72	4	GO:0032421
GeneOntologyCellularComponent	apical plasma membrane	CA12 CYP4F8 KL MYO7A DSTYK TMEM30A USH2A ABCG8	2.65e-04	487	72	8	GO:0016324
GeneOntologyCellularComponent	stereocilia coupling link	MYO7A USH2A	3.23e-04	8	72	2	GO:0002139
GeneOntologyCellularComponent	basement membrane	HMCN2 TNC USH2A AGRN	8.36e-04	122	72	4	GO:0005604
GeneOntologyCellularComponent	PML body	HIPK3 MAGEA11 HIPK2 TOP3A	9.16e-04	125	72	4	GO:0016605
GeneOntologyCellularComponent	apical part of cell	CA12 CYP4F8 KL MYO7A DSTYK TMEM30A USH2A ABCG8	9.60e-04	592	72	8	GO:0045177
GeneOntologyCellularComponent	9+2 non-motile cilium	STRC STRCP1	1.04e-03	14	72	2	GO:0097732
GeneOntologyCellularComponent	kinocilium	STRC STRCP1	1.04e-03	14	72	2	GO:0060091
MousePheno	abnormal cochlear microphonics	MYO7A STRC STRCP1	4.03e-05	18	53	3	MP:0004412
MousePheno	abnormal cochlear potential	MYO7A STRC STRCP1	4.78e-05	19	53	3	MP:0006332
Domain	fn3	PTPRD TNC ROBO3 USH2A EPHA8	3.10e-04	162	68	5	PF00041
Domain	Protein_kinase_ATP_BS	CDK20 HIPK3 DSTYK HIPK2 MAP3K9 MAPK11 EPHA8	4.48e-04	379	68	7	IPR017441
Domain	FN3	PTPRD TNC ROBO3 USH2A EPHA8	5.68e-04	185	68	5	SM00060
Domain	FN3	PTPRD TNC ROBO3 USH2A EPHA8	7.90e-04	199	68	5	PS50853
Domain	FN3_dom	PTPRD TNC ROBO3 USH2A EPHA8	9.84e-04	209	68	5	IPR003961
Domain	PROTEIN_KINASE_ATP	CDK20 HIPK3 DSTYK HIPK2 MAP3K9 MAPK11 EPHA8	1.38e-03	459	68	7	PS00107
Domain	Ser/Thr_kinase_AS	CDK20 HIPK3 DSTYK HIPK2 MAP3K9 MAPK11	1.89e-03	357	68	6	IPR008271
Domain	S_TKc	CDK20 HIPK3 DSTYK HIPK2 MAP3K9 MAPK11	1.94e-03	359	68	6	SM00220
Domain	Prot_kinase_dom	CDK20 HIPK3 DSTYK HIPK2 MAP3K9 MAPK11 EPHA8	1.97e-03	489	68	7	IPR000719
Domain	PROTEIN_KINASE_ST	CDK20 HIPK3 DSTYK HIPK2 MAP3K9 MAPK11	2.03e-03	362	68	6	PS00108
Domain	PROTEIN_KINASE_DOM	CDK20 HIPK3 DSTYK HIPK2 MAP3K9 MAPK11 EPHA8	2.07e-03	493	68	7	PS50011
Domain	Pkinase	CDK20 HIPK3 DSTYK HIPK2 MAP3K9 MAPK11	2.62e-03	381	68	6	PF00069
Domain	Kinase-like_dom	CDK20 HIPK3 DSTYK HIPK2 MAP3K9 MAPK11 EPHA8	3.50e-03	542	68	7	IPR011009
Domain	Ig-like_fold	ISLR2 HMCN2 PTPRD TNC LINGO4 ROBO3 USH2A EPHA8	4.01e-03	706	68	8	IPR013783
Domain	Cys-rich_flank_reg_C	ISLR2 LINGO4 SLITRK1	4.33e-03	90	68	3	IPR000483
Domain	LRRCT	ISLR2 LINGO4 SLITRK1	4.33e-03	90	68	3	SM00082
Domain	Ig_I-set	HMCN2 PTPRD LINGO4 ROBO3	5.09e-03	190	68	4	IPR013098
Domain	I-set	HMCN2 PTPRD LINGO4 ROBO3	5.09e-03	190	68	4	PF07679
Domain	EGF_LAM_2	USH2A AGRN	5.32e-03	30	68	2	PS50027
Domain	EGF_LAM_1	USH2A AGRN	5.32e-03	30	68	2	PS01248
Domain	LRRNT	ISLR2 LINGO4 SLITRK1	5.49e-03	98	68	3	IPR000372
Domain	LRRNT	ISLR2 LINGO4 SLITRK1	5.49e-03	98	68	3	SM00013
Domain	DEAD_ATP_HELICASE	DDX53 DDX43	5.67e-03	31	68	2	PS00039
Domain	RNA-helicase_DEAD-box_CS	DDX53 DDX43	6.41e-03	33	68	2	IPR000629
Domain	bZIP_1	CREB3L4 CREM	6.80e-03	34	68	2	PF00170
Pubmed	Stereocilin connects outer hair cell stereocilia to one another and to the tectorial membrane.	MYO7A STRC STRCP1	5.35e-07	8	75	3	21165971
Pubmed	Clarin-2 is essential for hearing by maintaining stereocilia integrity and function.	MYO7A STRC STRCP1	1.57e-06	11	75	3	31448880
Pubmed	Otogelin, otogelin-like, and stereocilin form links connecting outer hair cell stereocilia to each other and the tectorial membrane.	MYO7A STRC STRCP1	1.57e-06	11	75	3	31776257
Pubmed	MYO7A and USH2A gene sequence variants in Italian patients with Usher syndrome.	MYO7A USH2A	4.59e-06	2	75	2	25558175
Pubmed	Mutations in myosin VIIA (MYO7A) and usherin (USH2A) in Spanish patients with Usher syndrome types I and II, respectively.	MYO7A USH2A	4.59e-06	2	75	2	12112664
Pubmed	The Study of a 231 French Patient Cohort Significantly Extends the Mutational Spectrum of the Two Major Usher Genes MYO7A and USH2A.	MYO7A USH2A	4.59e-06	2	75	2	34948090
Pubmed	Mutations in a new gene encoding a protein of the hair bundle cause non-syndromic deafness at the DFNB16 locus.	STRC STRCP1	4.59e-06	2	75	2	11687802
Pubmed	Characterisation of microvascular abnormalities using OCT angiography in patients with biallelic variants in USH2A and MYO7A.	MYO7A USH2A	4.59e-06	2	75	2	31266775
Pubmed	Dual-vector gene therapy restores cochlear amplification and auditory sensitivity in a mouse model of DFNB16 hearing loss.	STRC STRCP1	4.59e-06	2	75	2	34910522
Pubmed	CLINICAL PRESENTATION AND DISEASE COURSE OF USHER SYNDROME BECAUSE OF MUTATIONS IN MYO7A OR USH2A.	MYO7A USH2A	4.59e-06	2	75	2	27828912
Pubmed	The helicase HAGE expressed by malignant melanoma-initiating cells is required for tumor cell proliferation in vivo.	ABCB5 DDX43	4.59e-06	2	75	2	22393060
Pubmed	Novel mutations in MYO7A and USH2A in Usher syndrome.	MYO7A USH2A	4.59e-06	2	75	2	15823922
Pubmed	Association study between Gilles de la Tourette Syndrome and two genes in the Robo-Slit pathway located in the chromosome 11q24 linked/associated region.	ROBO3 SLITRK1	1.37e-05	3	75	2	17671968
Pubmed	Cochlear outer hair cell horizontal top connectors mediate mature stereocilia bundle mechanics.	STRC STRCP1	1.37e-05	3	75	2	30801007
Pubmed	The Genetics of Usher Syndrome in the Israeli and Palestinian Populations.	MYO7A USH2A	1.37e-05	3	75	2	29490346
Pubmed	Suppression of MAPK11 or HIPK3 reduces mutant Huntingtin levels in Huntington's disease models.	HIPK3 MAPK11	1.37e-05	3	75	2	29151587
Pubmed	The helicase HAGE prevents interferon-α-induced PML expression in ABCB5+ malignant melanoma-initiating cells by promoting the expression of SOCS1.	ABCB5 DDX43	1.37e-05	3	75	2	24525737
Pubmed	Structural basis for LAR-RPTP/Slitrk complex-mediated synaptic adhesion.	PTPRD SLITRK1	1.37e-05	3	75	2	25394468
Pubmed	Targeted next generation sequencing in Italian patients with Usher syndrome: phenotype-genotype correlations.	MYO7A USH2A	1.37e-05	3	75	2	29142287
Pubmed	Update on the Regulation of HIPK1, HIPK2 and HIPK3 Protein Kinases by microRNAs.	HIPK3 HIPK2	1.37e-05	3	75	2	29793420
Pubmed	Stereocilin-deficient mice reveal the origin of cochlear waveform distortions.	STRC STRCP1	2.75e-05	4	75	2	18849963
Pubmed	Estrogenic induction of spermatogenesis in the hypogonadal mouse.	HIPK3 HIPK2	2.75e-05	4	75	2	10919273
Pubmed	Usher syndromes due to MYO7A, PCDH15, USH2A or GPR98 mutations share retinal disease mechanism.	MYO7A USH2A	2.75e-05	4	75	2	18463160
Pubmed	Abemaciclib is a potent inhibitor of DYRK1A and HIP kinases involved in transcriptional regulation.	HIPK3 HIPK2	2.75e-05	4	75	2	34785661
Pubmed	Effect of tyrosine autophosphorylation on catalytic activity and subcellular localisation of homeodomain-interacting protein kinases (HIPK).	HIPK3 HIPK2	2.75e-05	4	75	2	25630557
Pubmed	Tenascin-C promotes melanoma progression by maintaining the ABCB5-positive side population.	TNC ABCB5	2.75e-05	4	75	2	20729912
Pubmed	Hemicentin-1 is an essential extracellular matrix component of the dermal-epidermal and myotendinous junctions.	HMCN2 TNC	2.75e-05	4	75	2	34504132
Pubmed	Dispersed DNA variants underlie hearing loss in South Florida's minority population.	MYO7A STRC	4.57e-05	5	75	2	37996878
Pubmed	The Protein Tyrosine Phosphatase Receptor Delta Regulates Developmental Neurogenesis.	EOMES PTPRD	4.57e-05	5	75	2	31914388
Pubmed	An unusually powerful mode of low-frequency sound interference due to defective hair bundles of the auditory outer hair cells.	STRC STRCP1	4.57e-05	5	75	2	24920589
Pubmed	Homeodomain-interacting protein kinase 1 modulates Daxx localization, phosphorylation, and transcriptional activity.	HIPK3 HIPK2	6.84e-05	6	75	2	12529400
Pubmed	Involvement of the Hipk family in regulation of eyeball size, lens formation and retinal morphogenesis.	HIPK3 HIPK2	6.84e-05	6	75	2	20579985
Pubmed	Homeodomain-interacting protein kinases, a novel family of co-repressors for homeodomain transcription factors.	HIPK3 HIPK2	6.84e-05	6	75	2	9748262
Pubmed	A SMAD1/5-YAP signalling module drives radial glia self-amplification and growth of the developing cerebral cortex.	EOMES ISLR2 AGRN	7.70e-05	38	75	3	32541003
Pubmed	Assembly of neuron- and radial glial-cell-derived extracellular matrix molecules promotes radial migration of developing cortical neurons.	EOMES TNC	9.57e-05	7	75	2	38512724
Pubmed	The roles of USH1 proteins and PDZ domain-containing USH proteins in USH2 complex integrity in cochlear hair cells.	MYO7A USH2A	9.57e-05	7	75	2	28031293
Pubmed	Slitrks control excitatory and inhibitory synapse formation with LAR receptor protein tyrosine phosphatases.	PTPRD SLITRK1	9.57e-05	7	75	2	23345436
Pubmed	Comprehensive Characterization of Tissues Derived from Animals at Different Regenerative Stages: A Comparative Analysis between Fetal and Adult Mouse Skin.	TNC AGRN	9.57e-05	7	75	2	37174615
Pubmed	Microarray-based mutation analysis of 183 Spanish families with Usher syndrome.	MYO7A USH2A	1.27e-04	8	75	2	19683999
Pubmed	UMD-USHbases: a comprehensive set of databases to record and analyse pathogenic mutations and unclassified variants in seven Usher syndrome causing genes.	MYO7A USH2A	1.27e-04	8	75	2	18484607
Pubmed	Molecular basis of human Usher syndrome: deciphering the meshes of the Usher protein network provides insights into the pathomechanisms of the Usher disease.	MYO7A USH2A	1.27e-04	8	75	2	16545802
Pubmed	A Novel Mutation in Cse1l Disrupts Brain and Eye Development with Specific Effects on Pax6 Expression.	EOMES CSE1L	1.64e-04	9	75	2	34287339
Pubmed	Genome-wide association analysis of total cholesterol and high-density lipoprotein cholesterol levels using the Framingham heart study data.	APOB ABCG8	1.64e-04	9	75	2	20370913
Pubmed	Linkage mapping of the Aldo-2, Pax-5, Ambp, and D4h9S3E loci on mouse chromosome 4 in the region of homology with human chromosome 9.	GALT TNC	1.64e-04	9	75	2	7508415
Pubmed	Neural conditional ablation of the protein tyrosine phosphatase receptor Delta PTPRD impairs gliogenesis in the developing mouse brain cortex.	EOMES PTPRD	2.04e-04	10	75	2	38487272
Pubmed	Massively parallel DNA sequencing facilitates diagnosis of patients with Usher syndrome type 1.	MYO7A USH2A	2.04e-04	10	75	2	24618850
Pubmed	Usher protein functions in hair cells and photoreceptors.	MYO7A USH2A	2.04e-04	10	75	2	24239741
Pubmed	Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins.	HMCN2 TNC APOB AGRN	2.87e-04	146	75	4	27068509
Pubmed	Transcription factors, cAMP-responsive element modulator (CREM) and Tisp40, act in concert in postmeiotic transcriptional regulation.	CREB3L4 CREM	2.99e-04	12	75	2	16595651
Pubmed	Characterization of spatial and temporal development of Type I and Type II hair cells in the mouse utricle using new cell-type-specific markers.	MYO7A TNC	2.99e-04	12	75	2	30455179
Pubmed	Overlapping roles for homeodomain-interacting protein kinases hipk1 and hipk2 in the mediation of cell growth in response to morphogenetic and genotoxic signals.	HIPK3 HIPK2	2.99e-04	12	75	2	16537918
Pubmed	Fbxo2VHC mouse and embryonic stem cell reporter lines delineate in vitro-generated inner ear sensory epithelia cells and enable otic lineage selection and Cre-recombination.	MYO7A TNC	3.52e-04	13	75	2	30179592
Pubmed	Proteomics analysis of cardiac extracellular matrix remodeling in a porcine model of ischemia/reperfusion injury.	TNC APOB AGRN	3.65e-04	64	75	3	22261194
Pubmed	Molecular characterization of the ankle-link complex in cochlear hair cells and its role in the hair bundle functioning.	MYO7A USH2A	5.40e-04	16	75	2	17567809
Pubmed	Cell type-specific Rab32 and Rab38 cooperate with the ubiquitous lysosome biogenesis machinery to synthesize specialized lysosome-related organelles.	AP1B1 AP3M2	5.40e-04	16	75	2	23247405
Pubmed	Autism risk gene POGZ promotes chromatin accessibility and expression of clustered synaptic genes.	EOMES SLITRK1	6.11e-04	17	75	2	34879283
Pubmed	Mammalian Otolin: a multimeric glycoprotein specific to the inner ear that interacts with otoconial matrix protein Otoconin-90 and Cerebellin-1.	STRC STRCP1	6.11e-04	17	75	2	20856818
Pubmed	NFIX regulates neural progenitor cell differentiation during hippocampal morphogenesis.	EOMES TNC	6.87e-04	18	75	2	23042739
Pubmed	Genome-wide characterization of shared and distinct genetic components that influence blood lipid levels in ethnically diverse human populations.	APOB ABCG8	6.87e-04	18	75	2	23726366
Pubmed	Expression patterns of transcribed human endogenous retrovirus HERV-K(HML-2) loci in human tissues and the need for a HERV Transcriptome Project.	ERVK-25 ERVK-24	6.87e-04	18	75	2	18664271
Pubmed	A genome-wide RNAi screen identifies multiple synthetic lethal interactions with the Ras oncogene.	CA12 ABCB5 MRPL30 DDX43 NUP205	7.58e-04	331	75	5	19490893
Pubmed	Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.	HIPK3 POLR1A AP1B1 MRPL30 HIPK2 MAP3K9 DDX43 MAPK11	7.65e-04	910	75	8	36736316
Pubmed	p38 and a p38-interacting protein are critical for downregulation of E-cadherin during mouse gastrulation.	SUPT20HL2 MAPK11	1.03e-03	22	75	2	16751104
Pubmed	Protein tyrosine phosphatase receptor delta acts as a neuroblastoma tumor suppressor by destabilizing the aurora kinase A oncogene.	PTPRD EPHA8	1.03e-03	22	75	2	22305495
Pubmed	Deficiency of STING Signaling in Embryonic Cerebral Cortex Leads to Neurogenic Abnormalities and Autistic-Like Behaviors.	EOMES IRF3	1.03e-03	22	75	2	33304758
Pubmed	Slitrk4 is required for the development of inhibitory neurons in the fear memory circuit of the lateral amygdala.	PTPRD SLITRK1	1.03e-03	22	75	2	38736483
Pubmed	A revised nomenclature for transcribed human endogenous retroviral loci.	ERVK-19 ERVK-25 ERVK-24	1.12e-03	94	75	3	21542922
Pubmed	Genome-wide association study to identify single nucleotide polymorphisms (SNPs) associated with the development of erectile dysfunction in African-American men after radiotherapy for prostate cancer.	DDX53 APOB	1.13e-03	23	75	2	20932654
Pubmed	Thalamic afferents influence cortical progenitors via ephrin A5-EphA4 interactions.	EOMES EPHA8	1.13e-03	23	75	2	25480914
Pubmed	Single-cell RNA-sequencing analysis of the developing mouse inner ear identifies molecular logic of auditory neuron diversification.	ISLR2 MYO7A	1.23e-03	24	75	2	35790771
Pubmed	Genetic variation in healthy oldest-old.	KL APOB	1.23e-03	24	75	2	19680556
Pubmed	Genome-wide association study of proneness to anger.	HIPK3 CSE1L	1.23e-03	24	75	2	24489884
Pubmed	Host genetic variation affects resistance to infection with a highly pathogenic H5N1 influenza A virus in mice.	MYO7A TRIM34	1.23e-03	24	75	2	19706712
Pubmed	Pax6 limits the competence of developing cerebral cortical cells to respond to inductive intercellular signals.	EOMES ROBO3	1.33e-03	25	75	2	36067211
Pubmed	Centrosome anchoring regulates progenitor properties and cortical formation.	EOMES TNC	1.33e-03	25	75	2	32238932
Pubmed	PARD3 dysfunction in conjunction with dynamic HIPPO signaling drives cortical enlargement with massive heterotopia.	EOMES TNC	1.44e-03	26	75	2	29899142
Pubmed	Chd2 Is Necessary for Neural Circuit Development and Long-Term Memory.	EOMES MYO7A	1.56e-03	27	75	2	30344048
Pubmed	Robo1 modulates proliferation and neurogenesis in the developing neocortex.	EOMES ROBO3	1.56e-03	27	75	2	24741061
Pubmed	High-throughput analyses of hnRNP H1 dissects its multi-functional aspect.	RIMKLB PTPRD HIPK2 ARHGEF12 TMEM30A IRF3 C1orf159 TMEM214	1.59e-03	1021	75	8	26760575
Pubmed	A trimeric Rab7 GEF controls NPC1-dependent lysosomal cholesterol export.	CSE1L POLR1A AP1B1 TMEM30A TMEM214	1.60e-03	392	75	5	33144569
Pubmed	Mouse Models of Inherited Retinal Degeneration with Photoreceptor Cell Loss.	GNPTAB TMEM30A IRF3 USH2A	1.64e-03	233	75	4	32290105
Pubmed	The splicing regulator PTBP2 controls a program of embryonic splicing required for neuronal maturation.	ARHGEF12 AGRN	1.67e-03	28	75	2	24448406
Pubmed	Profiling, Bioinformatic, and Functional Data on the Developing Olfactory/GnRH System Reveal Cellular and Molecular Pathways Essential for This Process and Potentially Relevant for the Kallmann Syndrome.	ISLR2 HIPK2	1.67e-03	28	75	2	24427155
Pubmed	Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.	APOB ABCG8	1.92e-03	30	75	2	19936222
Pubmed	The transcription factor gene Nfib is essential for both lung maturation and brain development.	EOMES ROBO3	1.92e-03	30	75	2	15632069
Pubmed	Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.	CA12 CYP4F8 C1orf159 APOB TMEM214 BTAF1 CDH16 NUP205	2.03e-03	1061	75	8	33845483
Cytoband	Xp22.11	SUPT20HL2 DDX53	5.28e-04	21	74	2	Xp22.11
Cytoband	15q15.3	STRC STRCP1	7.51e-04	25	74	2	15q15.3
GeneFamily	Fibronectin type III domain containing	PTPRD TNC ROBO3 USH2A EPHA8	4.68e-05	160	45	5	555
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	HMCN2 PTPRD LINGO4 ROBO3	6.79e-04	161	45	4	593
GeneFamily	DEAD-box helicases	DDX53 DDX43	4.90e-03	42	45	2	499
Coexpression	GSE14908_RESTING_VS_HDM_STIM_CD4_TCELL_NONATOPIC_PATIENT_DN	GLMP SUOX AP3M2 IRF3 MAPK11 ZNF654	1.88e-05	200	72	6	M7080
Coexpression	MARTENS_TRETINOIN_RESPONSE_UP	CDK20 CYP4F8 HMCN2 MYO7A SCN5A OR2C3 LINGO4 MAPK11 SLITRK1 EPHA8 NLRP6	2.05e-05	855	72	11	M2098
Coexpression	RIZKI_TUMOR_INVASIVENESS_3D_UP	HIPK3 CNKSR1 CYP4F8 CSE1L TNC INPP1	2.41e-05	209	72	6	M17026
CoexpressionAtlas	DevelopingKidney_e15.5_stage III -IV renal corpusc_emap-27945_top-relative-expression-ranked_1000	KL PTPRD GALT PELP1 HIPK2 ARHGEF12 TMEM30A IRF3 TRIM34 BTAF1 AGRN CDH16	1.45e-05	837	69	12	gudmap_developingKidney_e15.5_stage III -IV renal corpusc_1000
ToppCell	Thalamus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6-Excitatory_Neuron.Slc17a6.Ebf1_(Anterior_pretectal_nucleus_(APT))-\|Thalamus / BrainAtlas - Mouse McCarroll V32	TROAP APOB STRC NLRP6	2.23e-06	57	72	4	ef44602342511a9f90c93463628ad8b154cb26fb
ToppCell	Thalamus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6-Excitatory_Neuron.Slc17a6.Ebf1_(Anterior_pretectal_nucleus_(APT))\|Thalamus / BrainAtlas - Mouse McCarroll V32	TROAP APOB STRC NLRP6	2.23e-06	57	72	4	a3dc14f7a63cc70b2789770644e0b9453426c6f9
Disease	autosomal recessive nonsyndromic deafness 16 (implicated_via_orthology)	STRC STRCP1	4.78e-06	2	65	2	DOID:0110471 (implicated_via_orthology)
Disease	Usher syndrome type 2	MYO7A USH2A	1.43e-05	3	65	2	C0339534
Disease	level of Sterol ester (27:1/18:2) in blood serum	NKPD1 APOB ABCG8	2.56e-05	26	65	3	OBA_2045194
Disease	Usher syndrome (is_implicated_in)	MYO7A USH2A	2.86e-05	4	65	2	DOID:0050439 (is_implicated_in)
Disease	Usher Syndrome, Type II	MYO7A USH2A	4.76e-05	5	65	2	C1568249
Disease	familial hyperlipidemia (is_implicated_in)	APOB ABCG8	1.33e-04	8	65	2	DOID:1168 (is_implicated_in)
Disease	hepcidin:transferrin saturation ratio	SLITRK1 NLRP6	4.93e-04	15	65	2	EFO_0007902
Disease	Hypercholesterolemia, Familial	APOB ABCG8	7.15e-04	18	65	2	C0020445
Disease	Nonsyndromic Deafness	MYO7A TNC STRC	7.70e-04	81	65	3	C3711374
Disease	cholesterol to total lipids in small LDL percentage	APOB ABCG8	1.62e-03	27	65	2	EFO_0022241
Disease	arteriosclerosis (is_implicated_in)	APOB ABCG8	2.13e-03	31	65	2	DOID:2349 (is_implicated_in)

Protein segments in the cluster

Peptide	Gene	Start	Entry
QRWLVTPVQQPGTNK	EOMES	516	O95936
VLRILGTPNPQVWPE	CDK20	216	Q8IZL9
VQWLRSQIAIVPQEP	ABCB5	1086	Q2M3G0
WLNPPNTGARVITSI	GOT1L1	286	Q8NHS2
PVVLRSTVPVNTNRW	AGRN	1961	O00468
QIWINGQPSSPQLVR	ABCG8	131	Q9H221
IWVLAELRIQPGNPS	AP1B1	906	Q10567
PPNWQQLVSREVLLG	ARHGEF12	766	Q9NZN5
QWQLQIPGGTVVLEP	ISLR2	271	Q6UXK2
HPQWTPVVVILGLLQ	NUP205	621	Q92621
QLPTGQLSVVPWRRT	AP3M2	156	P53677
INVPQDILGIWVDPI	INPP1	141	P49441
TVWEVPQRLQGLRPV	MAPK11	16	Q15759
TQQILLPPAWQQLTG	HIPK2	711	Q9H2X6
GPQLQWSQDLPRVQV	MAGEA11	51	P43364
PWVRNIFIVTNGQIP	GNPTAB	341	Q3T906
LEWPLQGVPISLVIN	HMCN2	331	Q8NDA2
TPTIEWLQAGQPLRA	HMCN2	4331	Q8NDA2
NPTVLWTVFRNPVQI	CA12	231	O43570
PRWVLSQLQLQESGP	IGHV4-39	21	P01824
TSIVPQLLANLWGPQ	OR2C3	76	Q8N628
WLRSIQQVLQTQDPP	PELP1	131	Q8IZL8
VQPLQIRPGVLSQTW	HIPK3	661	Q9H422
VLGLPWGVLSQVQLQ	IGHV6-1	11	A0A0B4J1U7
KQIIQRITWVSPPAI	DSTYK	546	Q6XUX3
IFPVRGQVLQVQAPW	DDO	196	Q99489
EVIPPLIENRQSWSV	APOB	951	P04114
IQQSLTVLVPRVWPF	BTAF1	511	O14981
QNWLVEVPIVSPISR	ERVK-24	66	P61566
RPWQGQVEPQLLKTV	GALT	51	P07902
VSLLWQEPEQPNGII	EPHA8	456	P29322
QGFVRWLGPITPIIN	CYP4F8	86	P98187
CVIRNIQQSPWIPGN	ADGRF2	196	Q8IZF7
IQQSPWIPGNIAVIV	ADGRF2	201	Q8IZF7
QRLPAWQPILTAGTV	TMEM30A	36	Q9NV96
VSLEVIPNWLGPLQN	GLMP	41	Q8WWB7
LVRVNITPVVALWQP	KL	626	Q9UEF7
TPIQSQAWPIILQGI	DDX53	246	Q86TM3
TRQGQGRIWLVPPAL	C1orf159	251	Q96HA4
IHVQGVIQTPQPWVI	CREM	66	Q03060
TPIQSQAWPIVLQGI	DDX43	266	Q9NXZ2
PNVGLISIQLDQWSP	CREB3L4	131	Q8TEY5
RIPPDILVNWAVQIA	MAP3K9	236	P80192
AWPQCRVQTVRVQLP	NLRP6	781	P59044
LGPNPTVQRDWRLQT	CDH16	706	O75309
RTWLEVIQVEPPNGT	LINGO4	496	Q6UY18
QLSWQPPVLAERNGI	PTPRD	936	P23468
LIPTLAIITRWGNQP	MT-ND4	126	P03905
PRILPWLVSQLDLGQ	IRF3	6	Q14653
TGQIPPTLWQRVQAD	RUNDC1	361	Q96C34
TIVLNWRKPIQSNGP	USH2A	3516	O75445
LSEDQRQVISVPIWP	TRIM34	316	Q9BYJ4
PVTPWNVQELRQAVI	POLR1A	471	O95602
RLVVQWPPGRLQTVT	MRPL30	6	Q8TCC3
PTPRQAVAWVVLANQ	NKPD1	426	Q17RQ9
PGTWQTGLSQPVLRQ	SATL1	171	Q86VE3
LLVPWPLRRTSAQGQ	SCN5A	561	Q14524
PLIGIPQTINWETIA	SANBR	26	Q6NSI8
PQTINWETIARLVPG	SANBR	31	Q6NSI8
TRWQALVQVQPSVDP	STRC	186	Q7RTU9
LRPLTLQVPQGWAVL	SUPT20HL2	646	P0C7V6
LLGQPQPLTQEQWRS	CNKSR1	591	Q969H4
PGQVSLQQTLPWLRS	C11orf42	141	Q8N5U0
VSPGENQLPVWIPTR	ERVK-25	836	P63136
QPVLWERTGNIPALV	CSE1L	691	P55060
RGIPLPIQTFLWRQT	UNC80	16	Q8N2C7
IPGNWQIKIRPTAAI	SLITRK1	311	Q96PX8
QEPIVLGPRTLQVSW	ROBO3	676	Q96MS0
LPTGQWVGVQLPRNT	TNC	1021	P24821
LLQQVQGPRLPWTRL	TMEM214	471	Q6NUQ4
WQVPLPQLQVLQTAL	ZNF654	71	Q8IZM8
PSTPRVQQAQWLRGV	TROAP	361	Q12815
PQVVVVRVPTPWVQS	RIMKLB	71	Q9ULI2
LTVLVEQQTPDPRWG	TOP3A	376	Q13472
TRWQALVQVQPSVDP	STRCP1	186	A6NGW2
NVQPDTVAPIWNLRG	SUOX	516	P51687
VSPGENQLPVWIPTR	ERVK-19	841	Q9WJR5
QPSVPVGQLWVELLR	TUT7	546	Q5VYS8
WQQAVVGRSEPIPVL	ZNF785	371	A8K8V0
VNGTRTQPPSWLELQ	MYO7A	1236	Q13402