Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionfatty-acyl-CoA synthase activity

ACSM2A ACSM4 ACSM3 ACSM2B ACSM1

2.46e-148195GO:0004321
GeneOntologyMolecularFunctionmedium-chain fatty acid-CoA ligase activity

ACSM2A ACSM4 ACSM3 ACSM2B ACSM1

2.02e-1311195GO:0031956
GeneOntologyMolecularFunctiondecanoate-CoA ligase activity

ACSM2A ACSM4 ACSM2B ACSM1

5.85e-134194GO:0102391
GeneOntologyMolecularFunctionC-acyltransferase activity

ACSM2A ACSM4 ACSM3 ACSM2B ACSM1

8.87e-1221195GO:0016408
GeneOntologyMolecularFunctionfatty acid ligase activity

ACSM2A ACSM4 ACSM3 ACSM2B ACSM1

2.86e-1126195GO:0015645
GeneOntologyMolecularFunctionCoA-ligase activity

ACSM2A ACSM4 ACSM3 ACSM2B ACSM1

3.50e-1127195GO:0016405
GeneOntologyMolecularFunctionacid-thiol ligase activity

ACSM2A ACSM4 ACSM3 ACSM2B ACSM1

7.36e-1131195GO:0016878
GeneOntologyMolecularFunctionligase activity, forming carbon-sulfur bonds

ACSM2A ACSM4 ACSM3 ACSM2B ACSM1

3.23e-1041195GO:0016877
GeneOntologyMolecularFunctionbenzoate-CoA ligase activity

ACSM2A ACSM2B ACSM1

7.30e-103193GO:0018858
GeneOntologyMolecularFunctionligase activity

ACSM2A ACSM4 ACSM3 ACSM2B ACSM1

5.00e-07174195GO:0016874
GeneOntologyMolecularFunctionacyltransferase activity, transferring groups other than amino-acyl groups

ACSM2A ACSM4 ACSM3 ACSM2B ACSM1

2.34e-06238195GO:0016747
GeneOntologyMolecularFunctionATP-dependent activity

ACSM2A ABCA12 ACSM4 ACSM3 ACSM2B ACSM1

1.59e-05614196GO:0140657
GeneOntologyMolecularFunctionacyltransferase activity

ACSM2A RNF43 ACSM4 ACSM3 ACSM2B ACSM1

5.89e-05775196GO:0016746
GeneOntologyMolecularFunctionextracellular matrix binding

ITGA6 ITGA2B

2.17e-0373192GO:0050840
GeneOntologyMolecularFunctionintegrin binding

ITGA6 ITGA2B

1.18e-02175192GO:0005178
GeneOntologyMolecularFunctioncell adhesion molecule binding

ITGA6 HCFC1 ITGA2B

1.82e-02599193GO:0050839
GeneOntologyBiologicalProcessamide metabolic process

ACSM2A MTRR ABCA12 MTHFD2 ACSM4 ACSM3 ACSM2B ACSM1

7.99e-09511198GO:0043603
GeneOntologyBiologicalProcessthioester metabolic process

ACSM2A ACSM4 ACSM3 ACSM2B ACSM1

4.12e-08109195GO:0035383
GeneOntologyBiologicalProcessacyl-CoA metabolic process

ACSM2A ACSM4 ACSM3 ACSM2B ACSM1

4.12e-08109195GO:0006637
GeneOntologyBiologicalProcessnucleoside bisphosphate metabolic process

ACSM2A ACSM4 ACSM3 ACSM2B ACSM1

1.55e-07142195GO:0033865
GeneOntologyBiologicalProcessribonucleoside bisphosphate metabolic process

ACSM2A ACSM4 ACSM3 ACSM2B ACSM1

1.55e-07142195GO:0033875
GeneOntologyBiologicalProcesspurine nucleoside bisphosphate metabolic process

ACSM2A ACSM4 ACSM3 ACSM2B ACSM1

1.55e-07142195GO:0034032
GeneOntologyBiologicalProcesssulfur compound metabolic process

ACSM2A MTRR ACSM4 ACSM3 ACSM2B ACSM1

6.58e-07365196GO:0006790
GeneOntologyBiologicalProcessfatty acid biosynthetic process

ACSM2A ACSM4 ACSM3 ACSM2B ACSM1

6.76e-07191195GO:0006633
GeneOntologyBiologicalProcesscarboxylic acid biosynthetic process

ACSM2A MTRR ACSM4 ACSM3 ACSM2B ACSM1

7.59e-07374196GO:0046394
GeneOntologyBiologicalProcessorganic acid biosynthetic process

ACSM2A MTRR ACSM4 ACSM3 ACSM2B ACSM1

7.95e-07377196GO:0016053
GeneOntologyBiologicalProcessmonocarboxylic acid biosynthetic process

ACSM2A ACSM4 ACSM3 ACSM2B ACSM1

3.08e-06260195GO:0072330
GeneOntologyBiologicalProcesssmall molecule biosynthetic process

ACSM2A MTRR ACSM4 ACSM3 ACSM2B ACSM1

2.28e-05676196GO:0044283
GeneOntologyBiologicalProcesscarboxylic acid metabolic process

ACSM2A MTRR MTHFD2 ACSM4 ACSM3 ACSM2B ACSM1

2.32e-051035197GO:0019752
GeneOntologyBiologicalProcessoxoacid metabolic process

ACSM2A MTRR MTHFD2 ACSM4 ACSM3 ACSM2B ACSM1

2.68e-051058197GO:0043436
GeneOntologyBiologicalProcessorganic acid metabolic process

ACSM2A MTRR MTHFD2 ACSM4 ACSM3 ACSM2B ACSM1

2.78e-051064197GO:0006082
GeneOntologyBiologicalProcesslipid homeostasis

ACSM2A ABCA12 ACSM3 ACSM1

3.66e-05211194GO:0055088
GeneOntologyBiologicalProcessfatty acid metabolic process

ACSM2A ACSM4 ACSM3 ACSM2B ACSM1

4.90e-05461195GO:0006631
GeneOntologyBiologicalProcesspurine ribonucleotide metabolic process

ACSM2A ACSM4 ACSM3 ACSM2B ACSM1

8.06e-05512195GO:0009150
GeneOntologyBiologicalProcessskin morphogenesis

ITGA6 ABCA12

8.38e-0515192GO:0043589
GeneOntologyBiologicalProcessribonucleotide metabolic process

ACSM2A ACSM4 ACSM3 ACSM2B ACSM1

9.74e-05533195GO:0009259
GeneOntologyBiologicalProcessribose phosphate metabolic process

ACSM2A ACSM4 ACSM3 ACSM2B ACSM1

1.04e-04540195GO:0019693
GeneOntologyBiologicalProcessfolic acid metabolic process

MTRR MTHFD2

1.22e-0418192GO:0046655
GeneOntologyBiologicalProcesspurine nucleotide metabolic process

ACSM2A ACSM4 ACSM3 ACSM2B ACSM1

1.96e-04619195GO:0006163
GeneOntologyBiologicalProcesspurine-containing compound metabolic process

ACSM2A ACSM4 ACSM3 ACSM2B ACSM1

2.50e-04652195GO:0072521
GeneOntologyBiologicalProcessnucleotide metabolic process

ACSM2A ACSM4 ACSM3 ACSM2B ACSM1

3.12e-04684195GO:0009117
GeneOntologyBiologicalProcessnucleoside phosphate metabolic process

ACSM2A ACSM4 ACSM3 ACSM2B ACSM1

3.27e-04691195GO:0006753
GeneOntologyBiologicalProcessmonocarboxylic acid metabolic process

ACSM2A ACSM4 ACSM3 ACSM2B ACSM1

4.24e-04731195GO:0032787
GeneOntologyBiologicalProcessfolic acid-containing compound metabolic process

MTRR MTHFD2

4.43e-0434192GO:0006760
GeneOntologyBiologicalProcessnucleobase-containing small molecule metabolic process

ACSM2A ACSM4 ACSM3 ACSM2B ACSM1

5.28e-04767195GO:0055086
GeneOntologyBiologicalProcesspteridine-containing compound metabolic process

MTRR MTHFD2

6.14e-0440192GO:0042558
GeneOntologyBiologicalProcesslipid biosynthetic process

ACSM2A ACSM4 ACSM3 ACSM2B ACSM1

6.89e-04813195GO:0008610
GeneOntologyBiologicalProcesswater-soluble vitamin metabolic process

MTRR MTHFD2

2.09e-0374192GO:0006767
GeneOntologyBiologicalProcessorganophosphate metabolic process

ACSM2A ACSM4 ACSM3 ACSM2B ACSM1

3.12e-031142195GO:0019637
GeneOntologyBiologicalProcesscell adhesion mediated by integrin

ITGA6 ITGA2B

3.14e-0391192GO:0033627
GeneOntologyBiologicalProcessregulation of insulin secretion involved in cellular response to glucose stimulus

ABCA12 HCFC1

3.20e-0392192GO:0061178
GeneOntologyBiologicalProcessglucose homeostasis

ACSM2A ABCA12 HCFC1

3.48e-03338193GO:0042593
GeneOntologyBiologicalProcesscarbohydrate homeostasis

ACSM2A ABCA12 HCFC1

3.51e-03339193GO:0033500
GeneOntologyBiologicalProcessinsulin secretion involved in cellular response to glucose stimulus

ABCA12 HCFC1

3.92e-03102192GO:0035773
GeneOntologyBiologicalProcesscarbohydrate derivative metabolic process

ACSM2A ACSM4 ACSM3 ACSM2B ACSM1

4.25e-031226195GO:1901135
GeneOntologyBiologicalProcesschemical homeostasis

ACSM2A ABCA12 HCFC1 ACSM3 ACSM1

4.60e-031249195GO:0048878
GeneOntologyBiologicalProcessdicarboxylic acid metabolic process

MTRR MTHFD2

4.62e-03111192GO:0043648
GeneOntologyBiologicalProcessintegrin-mediated signaling pathway

ITGA6 ITGA2B

5.73e-03124192GO:0007229
GeneOntologyBiologicalProcesscholesterol homeostasis

ACSM3 ACSM1

5.73e-03124192GO:0042632
GeneOntologyBiologicalProcesssterol homeostasis

ACSM3 ACSM1

5.82e-03125192GO:0055092
GeneOntologyBiologicalProcessvitamin metabolic process

MTRR MTHFD2

6.57e-03133192GO:0006766
GeneOntologyBiologicalProcessxenobiotic metabolic process

ACSM2B ACSM1

7.35e-03141192GO:0006805
GeneOntologyCellularComponentmitochondrial matrix

ACSM2A MTHFD2 ACSM4 ACSM3 ACSM2B ACSM1

4.90e-06523196GO:0005759
GeneOntologyCellularComponentintegrin complex

ITGA6 ITGA2B

3.82e-0432192GO:0008305
GeneOntologyCellularComponentprotein complex involved in cell adhesion

ITGA6 ITGA2B

1.30e-0359192GO:0098636
HumanPhenoHomocystinuria

MTRR HCFC1

6.33e-051162HP:0002156
HumanPhenoMethylmalonic acidemia

MTRR HCFC1

1.21e-041562HP:0002912
HumanPhenoHyperhomocystinemia

MTRR HCFC1

1.38e-041662HP:0002160
HumanPhenoIncreased sulfur amino acid level in urine

MTRR HCFC1

1.56e-041762HP:0033095
HumanPhenoAbnormal circulating homocysteine concentration

MTRR HCFC1

1.75e-041862HP:0010919
HumanPhenoMethylmalonic aciduria

MTRR HCFC1

2.40e-042162HP:0012120
HumanPhenoAcidemia

MTRR HCFC1

3.43e-042562HP:0032368
HumanPhenoAbnormality of vitamin B12 metabolism

MTRR HCFC1

5.65e-043262HP:0004341
HumanPhenoAminoaciduria

MTRR HCFC1

6.76e-043562HP:0002903
HumanPhenoAbnormal circulating sulfur amino acid concentration

MTRR HCFC1

7.16e-043662HP:0004339
MousePhenoincreased circulating homocysteine level

MTRR HCFC1

6.19e-0513132MP:0012335
MousePhenoabnormal circulating homocysteine level

MTRR HCFC1

8.33e-0515132MP:0006076
DomainAMP-bd_C

ACSM2A ACSM4 ACSM3 ACSM2B ACSM1

3.77e-1217195IPR025110
DomainAMP-binding_C

ACSM2A ACSM4 ACSM3 ACSM2B ACSM1

3.77e-1217195PF13193
DomainAMP-binding_CS

ACSM2A ACSM4 ACSM3 ACSM2B ACSM1

3.99e-1126195IPR020845
DomainAMP_BINDING

ACSM2A ACSM4 ACSM3 ACSM2B ACSM1

5.95e-1128195PS00455
DomainAMP-binding

ACSM2A ACSM4 ACSM3 ACSM2B ACSM1

8.62e-1130195PF00501
DomainAMP-dep_Synth/Lig

ACSM2A ACSM4 ACSM3 ACSM2B ACSM1

8.62e-1130195IPR000873
DomainIntegrin_alpha_C_CS

ITGA6 ITGA2B

1.17e-0416192IPR018184
DomainIntegrin_alpha

ITGA6 ITGA2B

1.49e-0418192IPR000413
DomainINTEGRIN_ALPHA

ITGA6 ITGA2B

1.49e-0418192PS00242
DomainIntegrin_alpha-2

ITGA6 ITGA2B

1.49e-0418192IPR013649
DomainIntegrin_alpha2

ITGA6 ITGA2B

1.49e-0418192PF08441
DomainInt_alpha

ITGA6 ITGA2B

1.66e-0419192SM00191
DomainInt_alpha_beta-p

ITGA6 ITGA2B

1.66e-0419192IPR013519
DomainFG_GAP

ITGA6 ITGA2B

2.24e-0422192PS51470
DomainFG-GAP

ITGA6 ITGA2B

2.67e-0424192PF01839
DomainFG-GAP

ITGA6 ITGA2B

2.67e-0424192IPR013517
DomainIntegrin_dom

ITGA6 ITGA2B

2.90e-0425192IPR032695
PathwayREACTOME_AMINO_ACID_CONJUGATION

ACSM2A ACSM4 ACSM2B ACSM1

2.13e-117144MM14598
PathwayREACTOME_AMINO_ACID_CONJUGATION

ACSM2A ACSM4 ACSM2B ACSM1

7.65e-119144M26968
PathwayREACTOME_CONJUGATION_OF_SALICYLATE_WITH_GLYCINE

ACSM2A ACSM4 ACSM2B

1.56e-086143MM14693
PathwayKEGG_BUTANOATE_METABOLISM

ACSM2A ACSM4 ACSM3 ACSM1

2.77e-0834144M3397
PathwayREACTOME_PHASE_II_CONJUGATION_OF_COMPOUNDS

ACSM2A MTRR ACSM4 ACSM2B ACSM1

4.35e-08107145MM14595
PathwayREACTOME_PHASE_II_CONJUGATION_OF_COMPOUNDS

ACSM2A MTRR ACSM4 ACSM2B ACSM1

4.77e-08109145M18788
PathwayREACTOME_BIOLOGICAL_OXIDATIONS

ACSM2A MTRR ACSM4 ACSM2B ACSM1

1.54e-06219145MM14838
PathwayREACTOME_BIOLOGICAL_OXIDATIONS

ACSM2A MTRR ACSM4 ACSM2B ACSM1

1.58e-06220145M10320
PathwayREACTOME_ASPIRIN_ADME

ACSM2A ACSM4 ACSM2B

1.01e-0544143M45014
PathwayREACTOME_ASPIRIN_ADME

ACSM2A ACSM4 ACSM2B

1.08e-0545143MM15694
PathwayREACTOME_CONJUGATION_OF_BENZOATE_WITH_GLYCINE

ACSM2B ACSM1

1.37e-056142M27037
PathwayREACTOME_DRUG_ADME

ACSM2A ACSM4 ACSM2B

1.54e-04109143M45012
PathwayREACTOME_DRUG_ADME

ACSM2A ACSM4 ACSM2B

1.99e-04119143MM15692
PathwayPID_INTEGRIN_CS_PATHWAY

ITGA6 ITGA2B

2.94e-0426142M47
PathwayWP_ONECARBON_METABOLISM

MTRR MTHFD2

3.66e-0429142M39471
PathwayWP_ONECARBON_METABOLISM

MTRR MTHFD2

5.05e-0434142MM15859
PathwayWP_FOLATE_METABOLISM

MTRR MTHFD2

2.07e-0369142M39617
PathwayWP_ARRHYTHMOGENIC_RIGHT_VENTRICULAR_CARDIOMYOPATHY

ITGA6 ITGA2B

2.37e-0374142M39462
PathwayKEGG_ARRHYTHMOGENIC_RIGHT_VENTRICULAR_CARDIOMYOPATHY_ARVC

ITGA6 ITGA2B

2.37e-0374142M16376
PathwayREACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS

ITGA6 ITGA2B

2.50e-0376142MM14867
PathwayKEGG_HYPERTROPHIC_CARDIOMYOPATHY_HCM

ITGA6 ITGA2B

2.98e-0383142M8728
PathwayKEGG_SMALL_CELL_LUNG_CANCER

ITGA6 ITGA2B

3.05e-0384142M3228
PathwayKEGG_ECM_RECEPTOR_INTERACTION

ITGA6 ITGA2B

3.05e-0384142M7098
PathwayREACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS

ITGA6 ITGA2B

3.12e-0385142M16441
PathwayKEGG_HEMATOPOIETIC_CELL_LINEAGE

ITGA6 ITGA2B

3.27e-0387142M6856
PathwayKEGG_DILATED_CARDIOMYOPATHY

ITGA6 ITGA2B

3.49e-0390142M835
PathwayWP_SMALL_CELL_LUNG_CANCER

ITGA6 ITGA2B

3.96e-0396142M39834
PathwayWP_INTEGRINMEDIATED_CELL_ADHESION

ITGA6 ITGA2B

4.46e-03102142M39577
PathwayWP_INTEGRINMEDIATED_CELL_ADHESION

ITGA6 ITGA2B

4.46e-03102142MM15830
PathwayWP_ADHD_AND_AUTISM_ASD_PATHWAYS

MTRR MTHFD2 HCFC1

5.15e-03367143M48346
PathwayREACTOME_METABOLISM_OF_WATER_SOLUBLE_VITAMINS_AND_COFACTORS

MTRR MTHFD2

6.12e-03120142MM14771
PathwayWP_HIPPOMERLIN_SIGNALING_DYSREGULATION

ITGA6 ITGA2B

6.22e-03121142M39823
PathwayREACTOME_METABOLISM_OF_WATER_SOLUBLE_VITAMINS_AND_COFACTORS

MTRR MTHFD2

6.83e-03127142M27093
Pubmed

Comparative analyses of disease risk genes belonging to the acyl-CoA synthetase medium-chain (ACSM) family in human liver and cell lines.

ACSM2A ACSM2B

2.83e-07219219634011
Pubmed

The L513S polymorphism in medium-chain acyl-CoA synthetase 2 (MACS2) is associated with risk factors of the metabolic syndrome in a Caucasian study population.

ACSM2A ACSM2B

2.83e-07219216521160
Pubmed

Two medium-chain acyl-coenzyme A synthetase genes, SAH and MACS1, are associated with plasma high-density lipoprotein cholesterol levels, but they are not associated with essential hypertension.

ACSM3 ACSM1

2.83e-07219215361761
Pubmed

Molecular identification and characterization of two medium-chain acyl-CoA synthetases, MACS1 and the Sa gene product.

ACSM3 ACSM1

2.83e-07219211470804
Pubmed

Characterization of the CoA ligases of human liver mitochondria catalyzing the activation of short- and medium-chain fatty acids and xenobiotic carboxylic acids.

ACSM2B ACSM1

2.83e-07219210434065
Pubmed

Analyses of the genetic diversity and protein expression variation of the acyl: CoA medium-chain ligases, ACSM2A and ACSM2B.

ACSM2A ACSM2B

2.83e-07219229948332
Pubmed

Expression of Acsm2, a kidney-specific gene, parallels the function and maturation of proximal tubular cells.

ACSM2A ACSM2B

1.70e-06419232830538
Pubmed

CD36 associates with CD9 and integrins on human blood platelets.

ITGA6 ITGA2B

4.24e-06619211238109
Pubmed

Pharmacogenetic analysis of lipid responses to rosuvastatin in Chinese patients.

ACSM3 ACSM2B ACSM1

6.19e-066619320679960
Pubmed

Disorders of Intracellular Cobalamin Metabolism

MTRR HCFC1

1.27e-051019220301503
Pubmed

A mitochondrial protein compendium elucidates complex I disease biology.

ACSM2A MTHFD2 ACSM4 ACSM3 ACSM2B ACSM1

1.42e-05104719618614015
Pubmed

Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context.

ACSM2A MTHFD2 ACSM4 ACSM3 ACSM2B ACSM1

2.26e-05113619634800366
Pubmed

118 SNPs of folate-related genes and risks of spina bifida and conotruncal heart defects.

MTRR MTHFD2

2.56e-051419219493349
Pubmed

IgSF8: a developmentally and functionally regulated cell adhesion molecule in olfactory sensory neuron axons and synapses.

ITGA6 ITGA2B

5.34e-052019222687584
Pubmed

Estrogen-dependent uterine secretion of osteopontin activates blastocyst adhesion competence.

ITGA6 ITGA2B

7.10e-052319223152823
Pubmed

Upstream open reading frames cause widespread reduction of protein expression and are polymorphic among humans.

ACSM2A ACSM2B

8.42e-052519219372376
Pubmed

Perlecan regulates pericyte dynamics in the maintenance and repair of the blood-brain barrier.

ITGA6 ITGA2B

9.84e-052719231541017
Pubmed

Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.

ACSM2A MTHFD2 ACSM4 ACSM3 ACSM1

1.13e-0492619520877624
Pubmed

Oral facial clefts and gene polymorphisms in metabolism of folate/one-carbon and vitamin A: a pathway-wide association study.

MTRR MTHFD2

1.14e-042919219048631
Pubmed

Liver and brain differential expression of one-carbon metabolism genes during ontogenesis.

MTRR MTHFD2

1.48e-043319234702858
Pubmed

Polymorphisms in DNA repair and one-carbon metabolism genes and overall survival in diffuse large B-cell lymphoma and follicular lymphoma.

MTRR MTHFD2

1.76e-043619218830263
Pubmed

An association study of 45 folate-related genes in spina bifida: Involvement of cubilin (CUBN) and tRNA aspartic acid methyltransferase 1 (TRDMT1).

MTRR MTHFD2

3.27e-044919219161160
Pubmed

Genetic nomenclature for loci controlling surface antigens of mouse hemopoietic cells.

ITGA6 ITGA2B

3.83e-04531921431091
InteractionACSM2A interactions

ACSM2A ACSM3 ACSM2B

2.84e-094193int:ACSM2A
InteractionACSM2B interactions

ACSM2A ACSM2B

5.05e-064192int:ACSM2B
InteractionACSM3 interactions

ACSM2A ACSM3

1.00e-0416192int:ACSM3
InteractionFAM241A interactions

VIPR2 SVOPL TMEM245

1.15e-04102193int:FAM241A
Cytoband16p12.3

ACSM2A ACSM2B ACSM1

3.57e-073419316p12.3
CytobandEnsembl 112 genes in cytogenetic band chr16p12

ACSM2A ACSM3 ACSM2B ACSM1

7.06e-07172194chr16p12
GeneFamilyAcyl-CoA synthetase family

ACSM2A ACSM4 ACSM3 ACSM2B ACSM1

5.22e-122613540
GeneFamilyCD molecules|Integrin alpha subunits

ITGA6 ITGA2B

7.25e-05181321160
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

HCFC1 ITGA2B LMTK3

2.62e-04181133694
GeneFamilyADAM metallopeptidase domain containing|CD molecules

ITGA6 ITGA2B

3.15e-02394132471
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ACSM2A ACSM3 ACSM2B ACSM1

1.11e-061891943b48b0d220cc24d5170713d61fa91f5bb6c21841
ToppCellCOVID-19-kidney-Technical/muscle_(PCT)|COVID-19 / Disease (COVID-19 only), tissue and cell type

ACSM2A ABCA12 ACSM2B

2.70e-05139193a1945b07f177cde40e7eea03a19236ce76165857
ToppCellLPS-IL1RA-Endothelial-Mes-Like-Gen_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TMEM19 VIPR2 ACSM3

3.06e-0514519390ca38c02325c5c637c32efdef634b54cc3cd105
ToppCell3'_v3-lymph-node_spleen-Hematopoietic_progenitors-Progenitor_Erythro-Mega|lymph-node_spleen / Manually curated celltypes from each tissue

SVOPL ACSM3 ITGA2B

5.00e-051711933ecd0a074344179c57eb2d9a857ba594904d00fa
ToppCellTCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Non-Papillary_Muscle_Invasive_Urothelial_Carcinoma-9|TCGA-Bladder / Sample_Type by Project: Shred V9

TMEM19 ITGA6 ABCA12

5.00e-05171193adbcfa4bf6bc1c604535a24435924cdb091e2dd7
ToppCellmild-Myeloid-Eosinophils|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

SVOPL ACSM3 ITGA2B

5.00e-051711935c8198182495bda7a826e9d80aa467f4eb1094ec
ToppCellHealthy/Control-NK_CD56bright|World / Disease group and Cell class

ITGA6 RNF43 SVOPL

5.00e-0517119379d7efefdae267905af05f3001514b8b6934d86e
ToppCellwk_15-18-Hematologic-Myeloid-Eosinophil|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

MTHFD2 SVOPL ITGA2B

5.17e-05173193a85cead231e03945fabbc7762540ad21fe4299df
ToppCellCOVID-19-kidney-Distal_Epi_Doublet_(PCT)|kidney / Disease (COVID-19 only), tissue and cell type

ACSM2A RNF43 ACSM2B

5.45e-0517619336f77d878a53b30465b0dea8333a3865dba75613
ToppCellpdx-Tumor_cells-T2|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

ITGA6 ACSM3 ACSM1

5.45e-051761931e21f80cf0e695ffdd63e4a72cf1e3fa41b60341
ToppCell3'_v3-bone_marrow-Mast|bone_marrow / Manually curated celltypes from each tissue

SVOPL ACSM4 ITGA2B

5.82e-05180193b37ee81b792213d6595b4ec65d04bc35d83321c7
ToppCell3'_v3-bone_marrow-Mast-Mast_cells|bone_marrow / Manually curated celltypes from each tissue

SVOPL ACSM4 ITGA2B

5.92e-0518119330ec4635474ee0f0ea1415ec0ba7f008d97e8c1a
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Colon_Adenocarcinoma-5|TCGA-Colorectal / Sample_Type by Project: Shred V9

ABCA12 ACSM3 ACSM1

5.92e-051811938fcc9e77fee7c248df26b6c59b10e672242e2084
ToppCell3'_v3-lymph-node_spleen-Hematopoietic_Erythro-Mega-Erythrocytic_early|lymph-node_spleen / Manually curated celltypes from each tissue

ACSM3 ITGA2B ACSM1

6.11e-051831930d56e16d4868c752c7557acec212029eb469ed05
ToppCellwk_15-18-Hematologic-Myeloid-MEP|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

MTHFD2 SVOPL ITGA2B

6.21e-0518419319d61d0ab038b7e729e13a46f88b8cf31759485d
ToppCell3'-Child09-12-SmallIntestine-Endothelial-lymphatic_endothelial|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ACSM2A ITGA2B ACSM2B

6.31e-0518519318f5d9438c76e37988a7d17aa2a080af6bedbfc4
ToppCell3'-Child09-12-SmallIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ACSM2A ITGA2B ACSM2B

6.31e-051851939de1db2ce9e44956b1214daf6e1e161334679c88
ToppCellwk_20-22-Hematologic-Myeloid-MEP|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

MTHFD2 SVOPL ITGA2B

6.42e-05186193e6e9135a65da568b3a7d0e378f8ce9ae34483968
ToppCell3'_v3-blood-Hematopoietic_progenitors-Progenitor_Erythro-Mega|blood / Manually curated celltypes from each tissue

SVOPL ACSM3 ITGA2B

6.42e-0518619359c115bbbb4bca4ad80be1809d8a0422b8438ea3
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ACSM2A ACSM3 ACSM2B

6.52e-051871939d77ca45f7563bd6f2a0c1be5d99d93ad30983f7
ToppCellCOVID-19-kidney-CD-IC-B|kidney / Disease (COVID-19 only), tissue and cell type

ITGA6 VIPR2 SVOPL

6.52e-05187193ce05b89860573fe0356102e2998d1ef6d1968034
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ACSM2A ACSM3 ACSM2B

6.73e-0518919328b502611829e4a24caff2562545c7db97686099
ToppCell3'-GW_trimst-1-SmallIntestine-Endothelial-blood_vessel_EC-Mature_arterial_EC|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ACSM2A ITGA6 ACSM2B

6.73e-051891931d660bceee449aebf12fc9af4c74af246837b27a
ToppCell10x_3'_v3-bone_marrow_(10x_3'_v3)-hematologic-hematopoietic_progenitor-common_myeloid_progenitor|bone_marrow_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

SVOPL ACSM3 ITGA2B

6.73e-0518919356156325cc36b1329bf483f81bb74f371ef15e20
ToppCellPCW_07-8.5-Epithelial-Epithelial_alveolar-distal-epi_SFTPC^high_distal_(9)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ITGA6 ACSM3 ACSM1

6.73e-051891935d9da836ce4308b8458bb3be3871a0aca734b6cd
ToppCellCOVID-19-kidney-PCT-S2|kidney / Disease (COVID-19 only), tissue and cell type

ACSM2A ACSM3 ACSM2B

6.73e-051891930be5c669b6b308bd98ddb70c84877c62a6244bbd
ToppCellPCW_07-8.5-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ITGA6 ACSM3 ACSM1

6.83e-05190193625c08a0e5227efc46daa512fd579c3938ff76c7
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ACSM2A ACSM3 ACSM2B

6.83e-05190193989d4eefd22d66ecb857836f8fdbcf41e3047f84
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ACSM2A ACSM3 ACSM2B

6.94e-051911931cb02007adb344f17ef73d58890f91298c7cf5a1
ToppCell3'-Pediatric_IBD-SmallIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ACSM2A ITGA2B ACSM2B

6.94e-05191193361b123c8289015206d5e706ab2c615d9a724179
ToppCell3'-Pediatric_IBD-SmallIntestine-Endothelial-lymphatic_endothelial|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ACSM2A ITGA2B ACSM2B

6.94e-05191193011dc22c488369734749e839d65d52fe46b6a1a4
ToppCellILEUM-inflamed-(7)_Endothelial_cell-(7)_Lymphatics|(7)_Endothelial_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

ACSM2A ITGA2B ACSM2B

7.05e-05192193d43caf42ec744e895137f31ef65a990e250669d2
ToppCellPCW_07-8.5-Epithelial-Epithelial_alveolar-distal|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ITGA6 ACSM3 ACSM1

7.05e-05192193b7c01e12b3e9be960a741b08835f1dfff65d0d47
ToppCell3'_v3-bone_marrow-Hematopoietic_progenitors-Progenitor_Erythro-Mega|bone_marrow / Manually curated celltypes from each tissue

SVOPL ACSM3 ITGA2B

7.05e-05192193cbc304c704e8524eee24a1619d0fbb2cf96c4976
ToppCell3'-GW_trimst-1-SmallIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ACSM2A ITGA6 ACSM2B

7.16e-051931931b69f92c6a7a2516e393d3f3c371407ec791343d
ToppCellPCW_07-8.5-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^medium_distal_(2)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ITGA6 ACSM3 ACSM1

7.16e-051931934b8202fcfe639a73f69a13f48fc3601ade256346
ToppCellerythropoietic-CD34+_Pro-erythroblast|World / Lineage and Cell class

SVOPL ACSM3 ITGA2B

7.27e-05194193cd12d01f6f2f12bbc33ed523bc678d3965074974
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ACSM2A ITGA6 ACSM2B

7.27e-051941937002937e8903e037332a215d00fbc7c7843b33f2
ToppCellerythropoietic-CD34+_Pro-erythroblast|erythropoietic / Lineage and Cell class

SVOPL ACSM3 ITGA2B

7.38e-05195193cd3d8fa6e18c0508cdfb64bb879d90b211badee5
ToppCellBronchial-NucSeq-Stromal-Mesofibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

VIPR2 ABCA12 ACSM1

7.49e-0519619396e5c6d155273e82ebafa180df8bb589c3e3e54e
ToppCellBronchial-NucSeq-Stromal-Mesofibroblastic-Mesothelia|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

VIPR2 ABCA12 ACSM1

7.49e-05196193ce13af36fc2932e8125013041742593ff3d07e86
ToppCellhematopoetic_progenitors-CD34+_MEP_1|hematopoetic_progenitors / Lineage and Cell class

SVOPL ACSM3 ITGA2B

7.61e-051971936172a1b98ff840d9174b1ab20ba0c202a7ef87af
ToppCellEpithelial_cells-Epithelial_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

ACSM2A ACSM3 ACSM2B

7.72e-0519819352e9d41a1726bc1140df6baec9f17a534448ac8b
ToppCellwk_08-11-Epithelial-Distal_epithelial_progenitor|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

RNF43 TMEM245 ACSM3

7.72e-05198193eda85a592527992b51a00f288cff0c3239c47e6f
ToppCellwk_08-11-Epithelial-Distal_epithelial_progenitor-epi-tip_intermediate|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

RNF43 TMEM245 ACSM3

7.72e-0519819384697f316d9195ebe838cf57f4dbdd9feea43bec
ToppCellEpithelial_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

ACSM2A ACSM3 ACSM2B

7.72e-05198193eeec789d226171f30799577cc37c07bdced2e3cb
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb-Inhibitory_Neuron.Gad1Gad2.Pvalb-Unc5b_(MGE-derived_cortical_interneurons--Chandelier_cells)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

VIPR2 SVOPL

5.63e-0483192e7f7ad1cd8b08172ef2432a80554aa8174a6c675
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb-Inhibitory_Neuron.Gad1Gad2.Pvalb-Unc5b_(MGE-derived_cortical_interneurons--Chandelier_cells)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

VIPR2 SVOPL

5.63e-048319233fa6e4a01be4d9945b273c884066d4bfdeaa62d
ToppCellPosterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Syt6-Excitatory_Neuron.Slc17a7-Slc17a8.Syt6-Lancl3_(Cortical_Subplate_pyramidal_cells)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

CATSPERG ABCA12

6.33e-04881927838c65160cf81c02b923fc34f566c0610c8d81b
ToppCellPosterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Syt6-Excitatory_Neuron.Slc17a7-Slc17a8.Syt6-Lancl3_(Cortical_Subplate_pyramidal_cells)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

CATSPERG ABCA12

6.33e-0488192fcc15c5c30517c63a835b28627c5f779d9bcd17e
ToppCellTCGA-Testes-Primary_Tumor-Testicular_Germ_Cell_Tumor-Non-Seminoma-_Mature_Teratoma,_Yolk_Sac_Tumor|TCGA-Testes / Sample_Type by Project: Shred V9

ACSM2A ACSM2B

6.77e-0491192d10ccc33d7716fe43900d5d0fea668cd74a44cb0
ToppCellTCGA-Testes-Primary_Tumor-Testicular_Germ_Cell_Tumor-Non-Seminoma-_Mature_Teratoma,_Yolk_Sac_Tumor-4|TCGA-Testes / Sample_Type by Project: Shred V9

ACSM2A ACSM2B

7.68e-04971929a9cb3a5a7e58893d602e32c3202ddbef917f0de
ToppCellTCGA-Thryoid-Solid_Tissue_Normal-Thryoid_normal_tissue-Thryoid_normal_tissue-7|TCGA-Thryoid / Sample_Type by Project: Shred V9

ACSM2A ACSM2B

8.99e-04105192aa9de4333021fa02dd8e8325d0b51bb661dcc678
ToppCellCOVID-19-kidney-Epithelial_(Imm)|COVID-19 / Disease (COVID-19 only), tissue and cell type

ACSM2A ACSM2B

1.15e-031191927cde7c73bb71f5e1911706e51c2ea6dcc72930ac
ToppCellVE-CD4-CD8_2|VE / Condition, Cell_class and T cell subcluster

ITGA2B ACSM1

1.21e-031221926745035feaf807b6a6b9537ac9d5ee0e000196eb
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA6 SVOPL

1.39e-03131192d706405453408fbcfcabb1c7702b80f9e649ffca
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA6 SVOPL

1.50e-031361927cd22169fb71c6caf9feb203ad98be8480a54fba
ToppCell10x_3'_v3-blood_(10x_3'_v3)-hematologic-hematopoietic_progenitor-common_myeloid_progenitor|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

SVOPL ACSM3

1.52e-031371926d90da42dcc06aa895f920218055068f3c76d57d
ToppCellhealthy_donor-Lymphocytic-T_cell-CD4+_T_cell_(ISG_high)|healthy_donor / Disease condition, Lineage, Cell class and subclass

RNF43 ACSM3

1.54e-0313819297f5dc17522462133e582b508ad0ef036e656872
ToppCellfacs-Aorta-Heart-3m-Myeloid-nan|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CATSPERG ABCA12

1.57e-0313919222a769d5195ed761ef333ef542746e1ba617a698
ToppCellfacs-Thymus-nan-3m-Epithelial-epithelial_cell_of_thymus|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CATSPERG ITGA2B

1.59e-03140192115bd770a9d5e6f007a9aa0eadf5dba46d500107
ToppCellfacs-Thymus-nan-3m-Epithelial|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CATSPERG ITGA2B

1.59e-0314019222d126e80bf7d9c0ca6ec686b5cc66fa584a1ab6
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SVOPL TMEM185B

1.59e-03140192e64f6aa57bc069cfe970089bd1c298433bfaf771
ToppCellfacs-Thymus-nan-3m-Epithelial-TECs|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CATSPERG ITGA2B

1.59e-0314019262d1ef8cb78618ed89cac7ec89d7f54de06a90c7
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Vipr2|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ITGA6 VIPR2

1.59e-0314019272c272f44e5600b3037c1dbf9d3a4669a35588d8
ToppCellTCGA-Uterus-Primary_Tumor-Uterine_Carcinoma-Uterine_Carcinosarcoma_Heterologous_Type-3|TCGA-Uterus / Sample_Type by Project: Shred V9

ACSM2A ACSM3

1.66e-03143192bcf702f976ab91f82a5a4beb0b7c74a372c42ae6
ToppCell356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_4|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

ACSM2A ACSM1

1.77e-031481921186ee0d15244fee74c1d09df3967c1b69f8ddce
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA6 SVOPL

1.80e-03149192cc911b454fe4e4b489885b9920baa7eb01a027ba
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_granulocytic|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ABCA12 ACSM2B

1.80e-03149192a22417286de8606f0cc94f86b70bce17aeefb9c2
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ABCA12 ACSM2B

1.80e-03149192c5eedb54ef2e0f131aa6730612c921bc19479632
ToppCellTCGA-Kidney|World / Sample_Type by Project: Shred V9

ACSM2A ACSM2B

1.84e-03151192e31974c0d0a0c644205a0ee6013ab74a09d8a306
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

VIPR2 ACSM2B

1.87e-03152192aa88084ba1851d879ece82baa516f6b46cbd2eb8
ToppCellVE-CD8-memory_CD4|VE / Condition, Cell_class and T cell subcluster

ACSM2A ITGA6

1.87e-031521929401b7770c1bdc87eba25e82922f5dd1c4fa37ee
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

VIPR2 MTHFD2

1.87e-031521920cb5f4dfae04e3f4eba502bbf229007d5fa3884d
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

VIPR2 MTHFD2

1.87e-03152192ba89ffb5a8bb33c188f854f54b39123b6d73496a
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ACSM2A ACSM2B

1.89e-03153192499670e716fc85ce76630fc813cec86f8419f2a1
ToppCellTCGA-Bone_and_Soft_Tissue-Solid_Tissue_Normal|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

ACSM2A ACSM2B

1.92e-0315419289a60a79d07466d7ad05888d10a72d3b1ab384af
ToppCellTCGA-Bone_and_Soft_Tissue-Solid_Tissue_Normal-Connective_tissue_normal|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

ACSM2A ACSM2B

1.92e-03154192f1fea1a87e977221fa125b62287368be9af4987d
ToppCellTCGA-Bone_and_Soft_Tissue-Solid_Tissue_Normal-Connective_tissue_normal-Connective_tissue_normal|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

ACSM2A ACSM2B

1.92e-03154192b5604c0b0b9b283352a3f612f40883b9123475d1
ToppCellTCGA-Bone_and_Soft_Tissue-Solid_Tissue_Normal-Connective_tissue_normal-Connective_tissue_normal-1|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

ACSM2A ACSM2B

1.92e-03154192160b170a3ade8b246843c9854af332475c047ba0
ToppCell(03)_Secretory-(2)_48hpi|(03)_Secretory / shred by cell type and Timepoint

ITGA6 ACSM3

1.94e-03155192d3b3d5764dfccaa4564f6063da7e13633a4f4b73
ToppCellfacs-Marrow-T_cells-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RNF43 LMTK3

1.97e-031561925caefdc6cc86f2ac52abe8c8da821db14f476915
ToppCellfacs-Marrow-T_cells-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RNF43 LMTK3

1.97e-03156192758f57dc10fc5cad200bf5b310c10ec9b1405f23
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA6 SVOPL

1.99e-03157192c17c5c01fcb65c453690c265ec4f300ecdfefd34
ToppCellPND28-Immune-Immune_Myeloid-Granulocytic-Basophil|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RNF43 ITGA2B

1.99e-031571928c42af7aa1f1b6f4fe2f8d00a8b4a800f121e804
ToppCellfacs-MAT-Fat-18m-Lymphocytic-NK_cell|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RNF43 LMTK3

1.99e-03157192e6846ffd1bb18bf0469bc6d49ab6cf3533d9cde6
ToppCellPND28-Immune-Immune_Myeloid-Granulocytic|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RNF43 ITGA2B

1.99e-03157192ee1be3c756b72fceac6b4ccb416dd4bd031a2193
ToppCellPND28-Immune-Immune_Myeloid-Granulocytic-Basophil-Basophil_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RNF43 ITGA2B

1.99e-03157192008f938a338f43c3251dcac574f1b4f689926c71
ToppCellfacs-Thymus-Flowthrough-24m-Lymphocytic-DN_to_DP_transition_(most_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM19 ACSM2B

2.01e-03158192c870fd17213129943562487338e2669e2930d719
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-nan|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACSM3 ACSM2B

2.04e-03159192c34a7d227dbda2d7c76f937e1a58552b14bd40b5
ToppCell10x5'-bone_marrow-Mast|bone_marrow / Manually curated celltypes from each tissue

SVOPL ITGA2B

2.04e-03159192c3d3570e83c5d25cc92fa3a7a8f0dc2f89a72913
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW19-Mesenchymal|GW19 / Sample Type, Dataset, Time_group, and Cell type.

CATSPERG MTHFD2

2.04e-03159192f34f2729a3872fbb2939e76ad35d7e25f71b8f57
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW19-Mesenchymal-Unfolded_protein_responsible_cell|GW19 / Sample Type, Dataset, Time_group, and Cell type.

CATSPERG MTHFD2

2.04e-03159192929ed98f6c2ad14e8d5af5c6f11a5a3d4b388cf7
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA6 SVOPL

2.07e-03160192174a4ab27114efcc63be36929b80680be3c35c9b
ToppCellPND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-Treg-Treg_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MTHFD2 ACSM1

2.07e-031601928308ca6f37986c526432a0fbc5f7ec2e75cfb6d7
ToppCellCOVID-CD8-CD8_2|COVID / Condition, Cell_class and T cell subcluster

SVOPL ACSM3

2.09e-03161192307dcc17475413cd9eb70c27bc447f938ee5723d
ToppCellAdult-Mesenchymal-airway_smooth_muscle_cell-D122|Adult / Lineage, Cell type, age group and donor

VIPR2 HCFC1

2.09e-0316119264891f6f2ee1693c8481e951b9346e2f92d602e3
ToppCell10x5'-bone_marrow-Mast-Mast_cells|bone_marrow / Manually curated celltypes from each tissue

SVOPL ITGA2B

2.09e-0316119215ba7e69699558353cfeecdcf1dbc2e147379ed6
ToppCellfacs-Pancreas-Exocrine-24m-Epithelial-pancreatic_acinar_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA12 ACSM2B

2.09e-03161192b9a17f41426bf715f30bf544a6795afaf37a3aa6
ToppCellfacs-Pancreas-Exocrine-24m-Epithelial-pancreatic_acinar_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA12 ACSM2B

2.09e-03161192f7a89c481f789f624102857be722c95fbeb47595
Drugbenzoyl-S-CoA

ACSM2A ACSM3 ACSM2B ACSM1

1.43e-0758194CID000122174
Drugphenylacetylglutamine

ACSM2A ACSM2B ACSM1

2.23e-0715193CID000092258
DrugAC1L194J

ACSM2A ACSM2B ACSM1

6.49e-0721193CID000000387
Drugacetic acids

ACSM2A ACSM2B ACSM1

1.59e-0628193CID000031229
DrugAC1NUTWC

ACSM2A ACSM2B

3.95e-064192CID005460914
Drughippuric acid

ACSM2A ACSM2B ACSM1

9.42e-0650193CID000000464
Drugglycine

ACSM2A MTHFD2 ACSM2B ACSM1

1.04e-05169194CID000000750
DrugTrichlormethiazide [133-67-5]; Down 200; 10.6uM; MCF7; HT_HG-U133A

VIPR2 ABCA12 HCFC1 RNF43

1.90e-051971943337_DN
DrugColchicine [64-86-8]; Down 200; 10uM; MCF7; HT_HG-U133A

TMEM19 VIPR2 ABCA12 HCFC1

1.90e-051971945675_DN
DrugNiridazole [61-57-4]; Up 200; 18.6uM; PC3; HT_HG-U133A

TMEM19 VIPR2 ITGA2B ACSM1

1.94e-051981944621_UP
DrugNalidixic acid sodium salt hydrate; Down 200; 14.6uM; MCF7; HT_HG-U133A

ITGA6 VIPR2 ABCA12 HCFC1

1.98e-051991944691_DN
DrugN-methylformamide

ITGA6 ACSM3 ITGA2B

2.18e-0566193CID000031254
DrugLaminin peptide 11

ITGA6 ITGA2B

2.37e-059192CID000219027
Drugbenzoate

ACSM2A ACSM3 ACSM2B ACSM1

2.99e-05221194CID000000242
Drugsalicyluric acid

ACSM2A ACSM2B

5.12e-0513192CID000010253
Diseaseindoleacetylglutamine measurement

ACSM2A ACSM3 ACSM1

4.52e-096193EFO_0800035
DiseaseX-21319 measurement

ACSM2A ACSM2B

3.93e-072192EFO_0800807
DiseaseX-11478 measurement

ACSM2A ACSM2B

1.18e-063192EFO_0021242
Disease4-hydroxyphenylacetylglutamine measurement

ACSM3 ACSM1

1.18e-063192EFO_0800688
Disease3-hydroxyhexanoate measurement

ACSM2A ACSM2B

3.92e-065192EFO_0800378
Diseaseindoleacetoylcarnitine measurement

ACSM2A ACSM2B

5.88e-066192EFO_0800106
DiseaseX-17676 measurement

ACSM3 ACSM2B

1.10e-058192EFO_0800785
DiseaseDisorders of Intracellular Cobalamin Metabolism

MTRR HCFC1

1.76e-0510192cv:CN043592
Diseaseurinary uromodulin measurement

ACSM2A ACSM3 ACSM2B

3.11e-0596193EFO_0005663
Diseasebeta-hydroxyisovalerate measurement

ACSM3 ACSM2B

3.56e-0514192EFO_0800125

Protein segments in the cluster

PeptideGeneStartEntry
PPWPRVRVVQVLWAL

CATSPERG

11

Q6ZRH7
RQPLWTLVLILWPVI

ABCA12

21

Q86UK0
VVLPRVPEWWLVILG

ACSM2A

111

Q08AH3
RLAVILPRIPEWWLV

ACSM4

116

P0C7M7
PAVLLQPRWKRVVGW

HCFC1

11

P51610
ELVVEPWIAGLWPAL

MTRR

136

Q9UBK8
ERLWIPLRWAAPELL

LMTK3

301

Q96Q04
GVPWWIILVAILAGI

ITGA6

1051

P23229
DRIIHWPWLVVFVPL

TMEM185B

161

Q9H7F4
TPWGVWEIIKRTGIP

MTHFD2

176

P13995
LQQPLGLTWPVVLIW

RNF43

151

Q68DV7
EERAIPIWWVLVGVL

ITGA2B

991

P08514
IPTIGWRWLIRVASI

SVOPL

196

Q8N434
WRWLIRVASIPGIIL

SVOPL

201

Q8N434
VMLPRVPEWWLVILG

ACSM2B

111

Q68CK6
LMLPRVPEWWLVAVG

ACSM1

116

Q08AH1
DRVILILPRVPEWWL

ACSM3

121

Q53FZ2
DHSVPWWVIRIPILI

VIPR2

276

P41587
WWVIRIPILISIIVN

VIPR2

281

P41587
PWRWLFSVVVPVLIV

TMEM19

51

Q96HH6
NLWIVQLLPVPIAVW

TMEM245

371

Q9H330