Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionchromatin binding

TOX FOXA1 NCOA2 FOXO1 NCOA3 DLX1 ARID1B

4.70e-06739207GO:0003682
GeneOntologyMolecularFunctiontranscription coactivator activity

NCOA2 NCOA3 MAML3 ARID1B ZIC3

1.00e-05303205GO:0003713
GeneOntologyMolecularFunctiontranscription coregulator activity

NCOA2 NCOA3 MAML3 ARID1B ZIC3

1.89e-04562205GO:0003712
GeneOntologyMolecularFunctionRNA polymerase II transcription regulatory region sequence-specific DNA binding

FOXA1 NCOA2 FOXO1 NCOA3 DLX1 PAX7 ZIC3

3.64e-041459207GO:0000977
GeneOntologyMolecularFunctionnuclear thyroid hormone receptor binding

NCOA2 NCOA3

5.25e-0434202GO:0046966
GeneOntologyMolecularFunctionprotein phosphatase 2A binding

FOXO1 CPD

8.01e-0442202GO:0051721
GeneOntologyMolecularFunctionRNA polymerase II cis-regulatory region sequence-specific DNA binding

FOXA1 NCOA2 FOXO1 DLX1 PAX7 ZIC3

1.05e-031244206GO:0000978
GeneOntologyMolecularFunctioncis-regulatory region sequence-specific DNA binding

FOXA1 NCOA2 FOXO1 DLX1 PAX7 ZIC3

1.17e-031271206GO:0000987
GeneOntologyMolecularFunctionnuclear estrogen receptor binding

NCOA2 NCOA3

1.27e-0353202GO:0030331
GeneOntologyMolecularFunctionnuclear receptor coactivator activity

NCOA2 NCOA3

1.68e-0361202GO:0030374
GeneOntologyMolecularFunctionDNA-binding transcription factor activity, RNA polymerase II-specific

FOXA1 FOXO1 NCOA3 DLX1 PAX7 ZIC3

2.02e-031412206GO:0000981
GeneOntologyMolecularFunctionDNA-binding transcription activator activity, RNA polymerase II-specific

FOXA1 FOXO1 NCOA3 ZIC3

2.07e-03560204GO:0001228
GeneOntologyMolecularFunctionDNA-binding transcription activator activity

FOXA1 FOXO1 NCOA3 ZIC3

2.16e-03566204GO:0001216
GeneOntologyMolecularFunctionprotein-macromolecule adaptor activity

NCOA2 NCOA3 MAML3 ARID1B ZIC3

4.89e-031160205GO:0030674
GeneOntologyMolecularFunctiontranscription factor binding

FOXA1 NCOA2 FOXO1 NCOA3

6.00e-03753204GO:0008134
GeneOntologyMolecularFunctionRNA polymerase II-specific DNA-binding transcription factor binding

FOXA1 NCOA2 NCOA3

7.92e-03417203GO:0061629
GeneOntologyBiologicalProcesspositive regulation of transcription by RNA polymerase II

TOX FOXA1 NCOA2 FOXO1 NCOA3 MAML3 DLX1 PAX7 ZIC3 SSBP4

9.85e-0813901910GO:0045944
GeneOntologyBiologicalProcesspositive regulation of intracellular steroid hormone receptor signaling pathway

FOXA1 NCOA2 NCOA3

5.36e-0718193GO:0033145
GeneOntologyBiologicalProcesspositive regulation of intracellular estrogen receptor signaling pathway

FOXA1 NCOA3

5.28e-0512192GO:0033148
GeneOntologyBiologicalProcessregulation of intracellular steroid hormone receptor signaling pathway

FOXA1 NCOA2 NCOA3

6.69e-0587193GO:0033143
GeneOntologyBiologicalProcessneuron fate commitment

FOXA1 DLX1 PAX7

7.65e-0591193GO:0048663
GeneOntologyBiologicalProcesscell fate commitment

TOX FOXA1 DLX1 PAX7

2.26e-04338194GO:0045165
GeneOntologyBiologicalProcessdorsal/ventral neural tube patterning

FOXA1 PAX7

2.38e-0425192GO:0021904
GeneOntologyBiologicalProcessnuclear receptor-mediated steroid hormone signaling pathway

FOXA1 NCOA2 NCOA3

2.51e-04136193GO:0030518
GeneOntologyBiologicalProcesscerebral cortex neuron differentiation

TOX DLX1

3.22e-0429192GO:0021895
GeneOntologyBiologicalProcesssteroid hormone receptor signaling pathway

FOXA1 NCOA2 NCOA3

3.69e-04155193GO:0043401
GeneOntologyBiologicalProcesspositive regulation of cell differentiation

TOX FOXA1 NCOA3 DLX1 ARID1B SLC9B2

4.11e-041141196GO:0045597
GeneOntologyBiologicalProcesscellular response to hormone stimulus

FOXA1 NCOA2 FOXO1 NCOA3 ARID1B

4.13e-04727195GO:0032870
GeneOntologyBiologicalProcessregulation of intracellular estrogen receptor signaling pathway

FOXA1 NCOA3

4.97e-0436192GO:0033146
GeneOntologyBiologicalProcessneural tube patterning

FOXA1 PAX7

7.77e-0445192GO:0021532
GeneOntologyBiologicalProcessnuclear receptor-mediated signaling pathway

FOXA1 NCOA2 NCOA3

7.99e-04202193GO:0141193
GeneOntologyBiologicalProcessregionalization

FOXA1 DLX1 PAX7 ZIC3

8.37e-04478194GO:0003002
GeneOntologyBiologicalProcessNotch signaling pathway

FOXA1 MAML3 DLX1

8.94e-04210193GO:0007219
GeneOntologyBiologicalProcesscentral nervous system neuron differentiation

TOX DLX1 PAX7

9.83e-04217193GO:0021953
GeneOntologyBiologicalProcessmRNA transcription by RNA polymerase II

NCOA2 ZIC3

1.04e-0352192GO:0042789
GeneOntologyBiologicalProcesschromatin organization

TOX FOXA1 NCOA3 ARID1B PAX7

1.07e-03896195GO:0006325
GeneOntologyBiologicalProcesschordate embryonic development

FOXA1 NCOA3 DLX1 PAX7 ZIC3

1.12e-03906195GO:0043009
GeneOntologyBiologicalProcesspattern specification process

FOXA1 DLX1 PAX7 ZIC3

1.19e-03526194GO:0007389
GeneOntologyBiologicalProcessestrogen receptor signaling pathway

FOXA1 NCOA3

1.24e-0357192GO:0030520
GeneOntologyBiologicalProcessmRNA transcription

NCOA2 ZIC3

1.24e-0357192GO:0009299
GeneOntologyBiologicalProcessembryo development ending in birth or egg hatching

FOXA1 NCOA3 DLX1 PAX7 ZIC3

1.26e-03929195GO:0009792
GeneOntologyBiologicalProcessstem cell population maintenance

FOXO1 NCOA3 ZIC3

1.27e-03237193GO:0019827
GeneOntologyBiologicalProcesscellular response to steroid hormone stimulus

FOXA1 NCOA2 NCOA3

1.30e-03239193GO:0071383
GeneOntologyBiologicalProcesspositive regulation of leukocyte differentiation

TOX ARID1B SLC9B2

1.35e-03242193GO:1902107
GeneOntologyBiologicalProcessmaintenance of cell number

FOXO1 NCOA3 ZIC3

1.35e-03242193GO:0098727
GeneOntologyBiologicalProcesspositive regulation of hemopoiesis

TOX ARID1B SLC9B2

1.35e-03242193GO:1903708
GeneOntologyBiologicalProcesshormone-mediated signaling pathway

FOXA1 NCOA2 NCOA3

1.38e-03244193GO:0009755
GeneOntologyBiologicalProcessRac protein signal transduction

EPS8 ARHGAP44

1.38e-0360192GO:0016601
GeneOntologyBiologicalProcesscellular response to oxygen-containing compound

FOXA1 NCOA2 FOXO1 NCOA3 ARID1B SLC9B2

1.46e-031450196GO:1901701
GeneOntologyBiologicalProcessprotein-DNA complex organization

TOX FOXA1 NCOA3 ARID1B PAX7

1.74e-03999195GO:0071824
GeneOntologyBiologicalProcessresponse to hormone

FOXA1 NCOA2 FOXO1 NCOA3 ARID1B

2.09e-031042195GO:0009725
GeneOntologyBiologicalProcessskeletal system development

DLX1 PAX7 ZIC3 SLC9B2

2.12e-03615194GO:0001501
GeneOntologyBiologicalProcesscellular response to oxidative stress

FOXA1 FOXO1 PLA2R1

2.37e-03295193GO:0034599
GeneOntologyBiologicalProcessstem cell differentiation

FOXA1 NCOA3 ZIC3

2.63e-03306193GO:0048863
GeneOntologyCellularComponentchromatin

FOXA1 NCOA2 FOXO1 NCOA3 DLX1 ARID1B PAX7

3.00e-041480207GO:0000785
HumanPhenoAlveolar rhabdomyosarcoma

FOXO1 PAX7

1.62e-05572HP:0006779
DomainDUF4927

NCOA2 NCOA3

1.09e-062202IPR032565
DomainDUF4927

NCOA2 NCOA3

1.09e-062202PF16279
DomainDUF1518

NCOA2 NCOA3

3.27e-063202SM01151
DomainNuc_rcpt_coact_Ncoa-typ

NCOA2 NCOA3

3.27e-063202IPR014920
DomainSRC-1

NCOA2 NCOA3

3.27e-063202IPR014935
DomainSRC-1

NCOA2 NCOA3

3.27e-063202PF08832
DomainDUF1518

NCOA2 NCOA3

3.27e-063202PF07469
Domain-

NCOA2 NCOA3

3.27e-0632024.10.630.10
DomainDUF1518

NCOA2 NCOA3

3.27e-063202IPR010011
DomainNuc_rec_co-act

NCOA2 NCOA3

3.27e-063202PF08815
DomainSrc1_rcpt_coact

NCOA2 NCOA3

3.27e-063202IPR008955
DomainNuclear_rcpt_coactivator

NCOA2 NCOA3

3.27e-063202IPR017426
DomainNuc_rcpt_coact

NCOA2 NCOA3

1.63e-056202IPR009110
DomainPAS

NCOA2 NCOA3

3.22e-0425202PF00989
DomainPAS_fold

NCOA2 NCOA3

3.22e-0425202IPR013767
DomainPAS

NCOA2 NCOA3

5.30e-0432202SM00091
DomainPAS

NCOA2 NCOA3

5.99e-0434202IPR000014
DomainPAS

NCOA2 NCOA3

5.99e-0434202PS50112
DomainTF_fork_head_CS_2

FOXA1 FOXO1

1.10e-0346202IPR030456
DomainTF_fork_head_CS_1

FOXA1 FOXO1

1.14e-0347202IPR018122
DomainFORK_HEAD_3

FOXA1 FOXO1

1.24e-0349202PS50039
DomainFH

FOXA1 FOXO1

1.24e-0349202SM00339
DomainFORK_HEAD_1

FOXA1 FOXO1

1.24e-0349202PS00657
DomainFORK_HEAD_2

FOXA1 FOXO1

1.24e-0349202PS00658
DomainForkhead

FOXA1 FOXO1

1.24e-0349202PF00250
DomainFork_head_dom

FOXA1 FOXO1

1.24e-0349202IPR001766
Domain-

FOXA1 FOXO1 PAX7

1.54e-032182031.10.10.10
DomainWHTH_DNA-bd_dom

FOXA1 FOXO1 PAX7

2.08e-03242203IPR011991
Domain-

NCOA2 NCOA3

5.99e-031092024.10.280.10
DomainHLH

NCOA2 NCOA3

6.75e-03116202SM00353
DomainBHLH

NCOA2 NCOA3

6.87e-03117202PS50888
DomainbHLH_dom

NCOA2 NCOA3

6.98e-03118202IPR011598
DomainSH3_1

EPS8 STAM2

1.31e-02164202PF00018
PathwayWP_PREGNANE_X_RECEPTOR_PATHWAY

NCOA2 FOXO1 NCOA3

8.47e-0632183M39567
PathwayWP_ENDODERM_DIFFERENTIATION

TOX FOXA1 FOXO1 ZIC3

2.78e-05143184M39591
PathwayWP_EGFEGFR_SIGNALING

FOXO1 NCOA3 EPS8 STAM2

4.54e-05162184M39334
PathwayKEGG_MEDICUS_REFERENCE_NUCLEAR_INITIATED_ESTROGEN_SIGNALING_PATHWAY

NCOA2 NCOA3

8.41e-0511182M47503
PathwayWP_HYPOXIADEPENDENT_SELFRENEWAL_OF_MYOBLASTS

FOXO1 PAX7

1.39e-0414182MM15832
PathwayPID_SMAD2_3NUCLEAR_PATHWAY

NCOA2 FOXO1 DLX1

1.45e-0482183M2
PathwayPID_ERB_GENOMIC_PATHWAY

NCOA2 NCOA3

1.60e-0415182M119
PathwayWP_RUBINSTEINTAYBI_SYNDROME_1

FOXO1 NCOA3

1.60e-0415182M48323
PathwayREACTOME_DEVELOPMENTAL_BIOLOGY

FOXA1 NCOA2 FOXO1 NCOA3 MAML3 ARID1B PAX7 ZIC3

1.91e-041432188M509
PathwayWP_ANDROGEN_RECEPTOR_SIGNALING

NCOA2 FOXO1 NCOA3

1.98e-0491183M39700
PathwayWP_FOXA2_PATHWAY

FOXA1 FOXO1

3.19e-0421182M42579
PathwayREACTOME_GASTRULATION

FOXA1 MAML3 PAX7

5.52e-04129183M46433
PathwayPID_RETINOIC_ACID_PATHWAY

NCOA2 NCOA3

6.56e-0430182M207
PathwayWP_CONSTITUTIVE_ANDROSTANE_RECEPTOR_PATHWAY

NCOA2 FOXO1

7.01e-0431182M39476
PathwayREACTOME_ESTROGEN_DEPENDENT_GENE_EXPRESSION

FOXA1 NCOA2 NCOA3

8.40e-04149183M27888
PathwayWP_MESODERMAL_COMMITMENT_PATHWAY

TOX FOXA1 ZIC3

9.08e-04153183M39546
PathwayREACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT

FOXO1 MAML3

1.29e-0342182M17541
PathwayWP_IL7_SIGNALING_PATHWAY

FOXO1 STAM2

1.35e-0343182MM15864
PathwayPID_HNF3A_PATHWAY

FOXA1 NCOA3

1.41e-0344182M285
PathwayPID_AR_TF_PATHWAY

NCOA2 FOXO1

2.04e-0353182M151
PathwayREACTOME_ESR_MEDIATED_SIGNALING

FOXA1 NCOA2 NCOA3

2.57e-03220183M27794
PathwayREACTOME_ESTROGEN_DEPENDENT_GENE_EXPRESSION

FOXA1 NCOA2

2.87e-0363182MM15613
PathwayPID_ERA_GENOMIC_PATHWAY

NCOA2 NCOA3

2.96e-0364182M200
PathwayPID_HIF1_TFPATHWAY

NCOA2 CP

3.15e-0366182M255
Pubmed

Genomic Resolution of DLX-Orchestrated Transcriptional Circuits Driving Development of Forebrain GABAergic Neurons.

TOX DLX1 PAX7

1.95e-081020331433982
Pubmed

Screening and association testing of common coding variation in steroid hormone receptor co-activator and co-repressor genes in relation to breast cancer risk: the Multiethnic Cohort.

FOXA1 NCOA2 NCOA3

1.10e-071720319183483
Pubmed

Retinoic acid signalling induces the differentiation of mouse fetal liver-derived hepatic progenitor cells.

FOXA1 NCOA2 NCOA3

2.86e-072320319737349
Pubmed

PAX7-FKHR fusion gene inhibits myogenic differentiation via NF-kappaB upregulation.

FOXO1 PAX7

3.14e-07220222374423
Pubmed

A novel SRC-2-dependent regulation of epithelial-mesenchymal transition in breast cancer cells.

NCOA2 NCOA3

3.14e-07220230048685
Pubmed

FOXO1 stimulates ceruloplasmin promoter activity in human hepatoma cells treated with IL-6.

FOXO1 CP

3.14e-07220221185807
Pubmed

Homeostatic levels of SRC-2 and SRC-3 promote early human adipogenesis.

NCOA2 NCOA3

3.14e-07220221220509
Pubmed

Uterine Tumor Resembling Ovarian Sex Cord Tumor: A Distinct Entity Characterized by Recurrent NCOA2/3 Gene Fusions.

NCOA2 NCOA3

3.14e-07220230273195
Pubmed

Effects of a Levonorgestrel-Releasing Intrauterine System on the Expression of Steroid Receptor Coregulators in Adenomyosis.

NCOA2 NCOA3

3.14e-07220226040939
Pubmed

Transcriptional modulation of the anti-apoptotic protein BCL-XL by the paired box transcription factors PAX3 and PAX3/FKHR.

FOXO1 PAX7

9.42e-07320210871843
Pubmed

The transcriptional coregulators TIF2 and SRC-1 regulate energy homeostasis by modulating mitochondrial respiration in skeletal muscles.

NCOA2 NCOA3

9.42e-07320221035760
Pubmed

Divergent transcriptional and transforming properties of PAX3-FOXO1 and PAX7-FOXO1 paralogs.

FOXO1 PAX7

9.42e-07320235604932
Pubmed

Expression and significance of androgen receptor coactivators in urothelial carcinoma of the bladder.

NCOA2 NCOA3

9.42e-07320218845648
Pubmed

PAX3/7-FOXO1 fusion status in older rhabdomyosarcoma patient population by fluorescent in situ hybridization.

FOXO1 PAX7

9.42e-07320222089931
Pubmed

The function of TIF2/GRIP1 in mouse reproduction is distinct from those of SRC-1 and p/CIP.

NCOA2 NCOA3

9.42e-07320212138202
Pubmed

Distinctive functions of p160 steroid receptor coactivators in proliferation of an estrogen-independent, tamoxifen-resistant breast cancer cell line.

NCOA2 NCOA3

9.42e-07320221059860
Pubmed

Detection of PAX3/PAX7-FKHR fusion transcripts in rhabdomyosarcoma and other small round cell tumors by 1-step reverse transcriptase polymerase chain reaction: a novel tool for diagnosis and differentiation.

FOXO1 PAX7

9.42e-07320222197543
Pubmed

Prognostic value of novel biomarkers in astrocytic brain tumors: nuclear receptor co-regulators AIB1, TIF2, and PELP1 are associated with high tumor grade and worse patient prognosis.

NCOA2 NCOA3

9.42e-07320221735116
Pubmed

[Alveolar rhabdomyosarcoma: Two fusion-negative cases lacking PAX3-FOXO1 and PAX7-FOXO1].

FOXO1 PAX7

9.42e-07320234980443
Pubmed

Absence of the steroid receptor coactivator-3 induces B-cell lymphoma.

NCOA2 NCOA3

9.42e-07320216675958
Pubmed

Pax7-FKHR transcriptional activity is enhanced by transcriptionally repressed MyoD.

FOXO1 PAX7

9.42e-07320221321994
Pubmed

Loss of Interdependent Binding by the FoxO1 and FoxA1/A2 Forkhead Transcription Factors Culminates in Perturbation of Active Chromatin Marks and Binding of Transcriptional Regulators at Insulin-sensitive Genes.

FOXA1 FOXO1

9.42e-07320226929406
Pubmed

Fusion gene-negative alveolar rhabdomyosarcoma is clinically and molecularly indistinguishable from embryonal rhabdomyosarcoma.

FOXO1 PAX7

9.42e-07320220351326
Pubmed

The nuclear receptor coactivators p300/CBP/cointegrator-associated protein (p/CIP) and transcription intermediary factor 2 (TIF2) differentially regulate PKA-stimulated transcriptional activity of steroidogenic factor 1.

NCOA2 NCOA3

9.42e-07320211923473
Pubmed

FLASH interacts with p160 coactivator subtypes and differentially suppresses transcriptional activity of steroid hormone receptors.

NCOA2 NCOA3

9.42e-07320215698540
Pubmed

Partial hormone resistance in mice with disruption of the steroid receptor coactivator-1 (SRC-1) gene.

NCOA2 NCOA3

9.42e-0732029506940
Pubmed

Structure and chromosomal locations of mouse steroid receptor coactivator gene family.

NCOA2 NCOA3

9.42e-07320210501088
Pubmed

Steroid receptor coactivators present a unique opportunity for drug development in hormone-dependent cancers.

NCOA2 NCOA3

9.42e-07320228390937
Pubmed

Co-expression of alternatively spliced forms of PAX3, PAX7, PAX3-FKHR and PAX7-FKHR with distinct DNA binding and transactivation properties in rhabdomyosarcoma.

FOXO1 PAX7

9.42e-07320215688409
Pubmed

Estrogen signaling in colorectal carcinoma microenvironment: expression of ERbeta1, AIB-1, and TIF-2 is upregulated in cancer-associated myofibroblasts and correlates with disease progression.

NCOA2 NCOA3

9.42e-07320219277704
Pubmed

Research resource: loss of the steroid receptor coactivators confers neurobehavioral consequences.

NCOA2 NCOA3

9.42e-07320223927929
Pubmed

FoxO1 and FoxA1/2 form a complex on DNA and cooperate to open chromatin at insulin-regulated genes.

FOXA1 FOXO1

9.42e-07320230142277
Pubmed

Vitamin D receptor and coactivators SRC2 and 3 regulate epidermis-specific sphingolipid production and permeability barrier formation.

NCOA2 NCOA3

9.42e-07320219052561
Pubmed

Pax3-fkhr and pax7-fkhr fusion genes impact outcome of alveolar rhabdomyosarcoma in children.

FOXO1 PAX7

9.42e-07320217613043
Pubmed

[Expression of fusion gene PAX3/PAX7-FKHR and chromosomal aberration in rhabdomyosarcoma].

FOXO1 PAX7

9.42e-07320217285543
Pubmed

PAX3-FKHR and PAX7-FKHR gene fusions are prognostic indicators in alveolar rhabdomyosarcoma: a report from the children's oncology group.

FOXO1 PAX7

9.42e-07320212039929
Pubmed

The genomic analysis of the impact of steroid receptor coactivators ablation on hepatic metabolism.

NCOA2 NCOA3

9.42e-07320216423883
Pubmed

miR-137 Targets p160 Steroid Receptor Coactivators SRC1, SRC2, and SRC3 and Inhibits Cell Proliferation.

NCOA2 NCOA3

1.88e-06420226066330
Pubmed

PAX--FKHR fusion genes and AChR-gamma in Chinese patients with rhabdomyosarcoma: diagnosis using formalin-fixed archival tissues.

FOXO1 PAX7

1.88e-06420218988640
Pubmed

Retinoid X receptor is a nonsilent major contributor to vitamin D receptor-mediated transcriptional activation.

NCOA2 NCOA3

1.88e-06420212893883
Pubmed

Estrogen receptor alpha/beta, AIB1, and TIF2 in colorectal carcinogenesis: do coregulators have prognostic significance?

NCOA2 NCOA3

1.88e-06420219198856
Pubmed

Ablation of steroid receptor coactivator-3 resembles the human CACT metabolic myopathy.

NCOA2 NCOA3

1.88e-06420222560224
Pubmed

P160/SRC/NCoA coactivators form complexes via specific interaction of their PAS-B domain with the CID/AD1 domain.

NCOA2 NCOA3

1.88e-06420218267973
Pubmed

Selective recruitment of p160 coactivators on glucocorticoid-regulated promoters in Schwann cells.

NCOA2 NCOA3

1.88e-06420215331759
Pubmed

Constitutive activation of transcription and binding of coactivator by estrogen-related receptors 1 and 2.

NCOA2 NCOA3

1.88e-06420210598588
Pubmed

Interactions of RXR with coactivators are differentially mediated by helix 11 of the receptor's ligand binding domain.

NCOA2 NCOA3

1.88e-06420211851396
Pubmed

Characterization of a Steroid Receptor Coactivator Small Molecule Stimulator that Overstimulates Cancer Cells and Leads to Cell Stress and Death.

NCOA2 NCOA3

1.88e-06420226267537
Pubmed

ALK expression in rhabdomyosarcomas: correlation with histologic subtype and fusion status.

FOXO1 PAX7

1.88e-06420218788887
Pubmed

Inducible short-term and stable long-term cell culture systems reveal that the PAX3-FKHR fusion oncoprotein regulates CXCR4, PAX3, and PAX7 expression.

FOXO1 PAX7

1.88e-06420215184910
Pubmed

Characterization of a novel small molecule subtype specific estrogen-related receptor alpha antagonist in MCF-7 breast cancer cells.

NCOA2 NCOA3

1.88e-06420219462000
Pubmed

Unique roles of p160 coactivators for regulation of breast cancer cell proliferation and estrogen receptor-alpha transcriptional activity.

NCOA2 NCOA3

1.88e-06420219095746
Pubmed

The molecular mechanisms of coactivator utilization in ligand-dependent transactivation by the androgen receptor.

NCOA2 NCOA3

1.88e-06420215563469
Pubmed

Nuclear hormone receptor coregulator GRIP1 suppresses, whereas SRC1A and p/CIP coactivate, by domain-specific binding of MyoD.

NCOA2 NCOA3

1.88e-06420215563453
Pubmed

A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.

TOX FOXA1 NCOA2 FOXO1 MAML3 PAX7

2.13e-0670920622988430
Pubmed

Transcription activation by the orphan nuclear receptor, chicken ovalbumin upstream promoter-transcription factor I (COUP-TFI). Definition of the domain involved in the glucocorticoid response of the phosphoenolpyruvate carboxykinase gene.

NCOA2 NCOA3

3.14e-06520210652338
Pubmed

Identification of COUP-TFII orphan nuclear receptor as a retinoic acid-activated receptor.

NCOA2 NCOA3

3.14e-06520218798693
Pubmed

Isoform-selective interactions between estrogen receptors and steroid receptor coactivators promoted by estradiol and ErbB-2 signaling in living cells.

NCOA2 NCOA3

3.14e-06520212554772
Pubmed

Redundant enhancement of mouse constitutive androstane receptor transactivation by p160 coactivator family members.

NCOA2 NCOA3

3.14e-06520217950690
Pubmed

Forkhead homologue in rhabdomyosarcoma functions as a bifunctional nuclear receptor-interacting protein with both coactivator and corepressor functions.

FOXO1 NCOA3

3.14e-06520211353774
Pubmed

SIP, a novel ankyrin repeat containing protein, sequesters steroid receptor coactivators in the cytoplasm.

NCOA2 NCOA3

3.14e-06520217476305
Pubmed

Ontogeny of steroid receptor coactivators in the hippocampus and their role in regulating postnatal HPA axis function.

NCOA2 NCOA3

3.14e-06520217854779
Pubmed

Dual role of the arginine methyltransferase CARM1 in the regulation of c-Fos target genes.

NCOA2 NCOA3

3.14e-06520218511550
Pubmed

Estrogen receptor-alpha interaction with the CREB binding protein coactivator is regulated by the cellular environment.

NCOA2 NCOA3

3.14e-06520214766010
Pubmed

SRC-1 and GRIP1 coactivate transcription with hepatocyte nuclear factor 4.

NCOA2 NCOA3

3.14e-0652029812974
Pubmed

The opposing transcriptional activities of the two isoforms of the human progesterone receptor are due to differential cofactor binding.

NCOA2 NCOA3

3.14e-06520210757795
Pubmed

Mechanistic relationship between androgen receptor polyglutamine tract truncation and androgen-dependent transcriptional hyperactivity in prostate cancer cells.

NCOA2 NCOA3

3.14e-06520214966121
Pubmed

Ligand-independent interactions of p160/steroid receptor coactivators and CREB-binding protein (CBP) with estrogen receptor-alpha: regulation by phosphorylation sites in the A/B region depends on other receptor domains.

NCOA2 NCOA3

3.14e-06520212714702
Pubmed

Regulation of transcription by a protein methyltransferase.

NCOA2 NCOA3

3.14e-06520210381882
Pubmed

Coactivator and corepressor gene expression in rat cerebellum during postnatal development and the effect of altered thyroid status.

NCOA2 NCOA3

3.14e-06520210803578
Pubmed

SRC-1 null mice exhibit moderate motor dysfunction and delayed development of cerebellar Purkinje cells.

NCOA2 NCOA3

3.14e-06520212514218
Pubmed

Ligands specify coactivator nuclear receptor (NR) box affinity for estrogen receptor subtypes.

NCOA2 NCOA3

3.14e-06520211376110
Pubmed

A novel partial agonist of peroxisome proliferator-activated receptor-gamma (PPARgamma) recruits PPARgamma-coactivator-1alpha, prevents triglyceride accumulation, and potentiates insulin signaling in vitro.

NCOA2 NCOA3

4.71e-06620216373399
Pubmed

Mutual antagonism of estrogen receptors alpha and beta and their preferred interactions with steroid receptor coactivators in human osteoblastic cell lines.

NCOA2 NCOA3

4.71e-06620212630920
Pubmed

Steroid receptor coactivator-3 is required for progesterone receptor trans-activation of target genes in response to gonadotropin-releasing hormone treatment of pituitary cells.

NCOA2 NCOA3

4.71e-06620216728408
Pubmed

Signaling within a coactivator complex: methylation of SRC-3/AIB1 is a molecular switch for complex disassembly.

NCOA2 NCOA3

4.71e-06620216923966
Pubmed

Cellular energy depletion resets whole-body energy by promoting coactivator-mediated dietary fuel absorption.

NCOA2 NCOA3

6.59e-06720221195347
Pubmed

BRCA1-IRIS regulates cyclin D1 expression in breast cancer cells.

NCOA2 NCOA3

6.59e-06720216860316
Pubmed

Characterization of the physical interaction between estrogen receptor alpha and JUN proteins.

NCOA2 NCOA3

6.59e-06720211477071
Pubmed

The transcriptional co-activator p/CIP binds CBP and mediates nuclear-receptor function.

NCOA2 NCOA3

6.59e-0672029192892
Pubmed

Temporal formation of distinct thyroid hormone receptor coactivator complexes in HeLa cells.

NCOA2 NCOA3

6.59e-06720211117530
Pubmed

Sestrin prevents atrophy of disused and aging muscles by integrating anabolic and catabolic signals.

FOXO1 PAX7

6.59e-06720231929511
Pubmed

The AF-1 domain of the orphan nuclear receptor NOR-1 mediates trans-activation, coactivator recruitment, and activation by the purine anti-metabolite 6-mercaptopurine.

NCOA2 NCOA3

6.59e-06720212709428
Pubmed

TRIM33 drives prostate tumor growth by stabilizing androgen receptor from Skp2-mediated degradation.

FOXA1 NCOA2 NCOA3 ARID1B

6.97e-0622020435785414
Pubmed

An atlas of combinatorial transcriptional regulation in mouse and man.

FOXA1 NCOA2 NCOA3 MAML3 DLX1 SSBP4

7.24e-0687720620211142
Pubmed

The activation function-1 domain of Nur77/NR4A1 mediates trans-activation, cell specificity, and coactivator recruitment.

NCOA2 NCOA3

8.78e-06820212082103
Pubmed

Identification of the antibiotic ionomycin as an unexpected peroxisome proliferator-activated receptor γ (PPARγ) ligand with a unique binding mode and effective glucose-lowering activity in a mouse model of diabetes.

NCOA2 NCOA3

8.78e-06820223178929
Pubmed

Synergistic enhancement of nuclear receptor function by p160 coactivators and two coactivators with protein methyltransferase activities.

NCOA2 NCOA3

8.78e-06820211050077
Pubmed

Regulation of SRC-3 (pCIP/ACTR/AIB-1/RAC-3/TRAM-1) Coactivator activity by I kappa B kinase.

NCOA2 NCOA3

8.78e-06820211971985
Pubmed

Alveolar rhabdomyosarcomas in conditional Pax3:Fkhr mice: cooperativity of Ink4a/ARF and Trp53 loss of function.

FOXO1 PAX7

8.78e-06820215489287
Pubmed

Concerted activation of ETS protein ER81 by p160 coactivators, the acetyltransferase p300 and the receptor tyrosine kinase HER2/Neu.

NCOA2 NCOA3

8.78e-06820214747462
Pubmed

Regulation of hormone-induced histone hyperacetylation and gene activation via acetylation of an acetylase.

NCOA2 NCOA3

8.78e-06820210490106
Pubmed

Targeting of SWI/SNF chromatin remodelling complexes to estrogen-responsive genes.

NCOA2 NCOA3

8.78e-06820212145209
Pubmed

Human transcription factor protein interaction networks.

FOXA1 NCOA2 NCOA3 ARID1B PAX7 ZIC3 SSBP4

9.43e-06142920735140242
Pubmed

Genome-wide interrogation of germline genetic variation associated with treatment response in childhood acute lymphoblastic leukemia.

NCOA3 ARID1B

1.13e-05920219176441
Pubmed

Regulation of somatic growth by the p160 coactivator p/CIP.

NCOA2 NCOA3

1.13e-05920211087842
Pubmed

Developmentally essential protein flightless I is a nuclear receptor coactivator with actin binding activity.

NCOA2 NCOA3

1.13e-05920214966289
Pubmed

Structural determinants of the agonist-independent association of human peroxisome proliferator-activated receptors with coactivators.

NCOA2 NCOA3

1.13e-05920215888456
Pubmed

Identification of a novel family of ankyrin repeats containing cofactors for p160 nuclear receptor coactivators.

NCOA2 NCOA3

1.13e-05920215184363
Pubmed

Development, maturation, and necessity of transcription factors in the mouse suprachiasmatic nucleus.

FOXO1 DLX1 ZIC3

1.16e-057720321525287
Pubmed

Agonist-specific Protein Interactomes of Glucocorticoid and Androgen Receptor as Revealed by Proximity Mapping.

NCOA2 NCOA3 ARID1B

1.20e-057820328611094
InteractionNFIA interactions

FOXA1 NCOA2 NCOA3 ARID1B PAX7

9.27e-07188205int:NFIA
InteractionTLE3 interactions

FOXA1 NCOA2 NCOA3 ARID1B PAX7 SSBP4

1.26e-06376206int:TLE3
InteractionNCOA3 interactions

FOXA1 NCOA2 NCOA3 ARID1B PAX7

2.20e-06224205int:NCOA3
InteractionDLX5 interactions

FOXA1 NCOA2 FOXO1

3.00e-0629203int:DLX5
InteractionPAX7 interactions

NCOA3 ARID1B PAX7 SSBP4

6.13e-06124204int:PAX7
InteractionNR5A2 interactions

FOXA1 NCOA2 NCOA3

8.70e-0641203int:NR5A2
InteractionNFIB interactions

FOXA1 NCOA3 ARID1B PAX7

1.05e-05142204int:NFIB
InteractionIGKV3-20 interactions

FOXA1 FOXO1

2.61e-058202int:IGKV3-20
InteractionHNF1B interactions

NCOA2 NCOA3 ARID1B PAX7

3.30e-05190204int:HNF1B
InteractionMYOD1 interactions

NCOA2 NCOA3 ARID1B PAX7

3.57e-05194204int:MYOD1
InteractionETV4 interactions

NCOA2 NCOA3 ARID1B

4.20e-0569203int:ETV4
InteractionNFIC interactions

FOXA1 NCOA3 ARID1B PAX7

4.87e-05210204int:NFIC
InteractionSOX7 interactions

NCOA2 NCOA3 ARID1B

7.04e-0582203int:SOX7
InteractionSOX10 interactions

NCOA2 NCOA3 ARID1B

9.92e-0592203int:SOX10
InteractionSOX17 interactions

NCOA2 NCOA3 ARID1B

1.09e-0495203int:SOX17
InteractionSMAD4 interactions

FOXO1 NCOA3 DLX1 CPD ARID1B

1.38e-04530205int:SMAD4
InteractionHNF4A interactions

NCOA2 FOXO1 NCOA3 ARID1B

1.38e-04275204int:HNF4A
InteractionDLX1 interactions

FOXA1 DLX1

1.42e-0418202int:DLX1
InteractionSMARCE1 interactions

NCOA2 NCOA3 EPS8 ARID1B

1.63e-04287204int:SMARCE1
InteractionPAX8 interactions

NCOA2 NCOA3 ARID1B

1.73e-04111203int:PAX8
InteractionTBR1 interactions

NCOA2 NCOA3 ARID1B

1.83e-04113203int:TBR1
InteractionLDB1 interactions

FOXA1 PAX7 SSBP4

1.92e-04115203int:LDB1
InteractionDLX2 interactions

NCOA2 DLX1

1.94e-0421202int:DLX2
InteractionTBXT interactions

NCOA2 NCOA3 ARID1B

1.97e-04116203int:TBXT
InteractionSATB1 interactions

FOXA1 FOXO1 PAX7

1.97e-04116203int:SATB1
InteractionSP7 interactions

NCOA2 NCOA3 DLX1 ARID1B

2.03e-04304204int:SP7
InteractionPPARG interactions

NCOA2 FOXO1 NCOA3 ARID1B

2.11e-04307204int:PPARG
InteractionCREBBP interactions

NCOA2 FOXO1 NCOA3 ARID1B PAX7

2.44e-04599205int:CREBBP
InteractionPAX9 interactions

NCOA2 NCOA3 ARID1B

2.76e-04130203int:PAX9
InteractionTLE6 interactions

NCOA3 SSBP4

2.77e-0425202int:TLE6
InteractionSOX15 interactions

NCOA2 NCOA3 ARID1B

3.50e-04141203int:SOX15
InteractionTRPS1 interactions

FOXA1 NCOA3 PAX7

3.65e-04143203int:TRPS1
InteractionETV1 interactions

NCOA2 NCOA3

3.74e-0429202int:ETV1
InteractionNCOA1 interactions

NCOA2 FOXO1 NCOA3

3.88e-04146203int:NCOA1
InteractionSATB2 interactions

FOXA1 FOXO1 PAX7

4.98e-04159203int:SATB2
InteractionLHX4 interactions

NCOA2 ARID1B SSBP4

5.64e-04166203int:LHX4
InteractionNRIP1 interactions

FOXA1 NCOA2 NCOA3

6.05e-04170203int:NRIP1
InteractionEGR2 interactions

NCOA2 NCOA3 ARID1B

6.15e-04171203int:EGR2
InteractionTLX1 interactions

NCOA2 NCOA3 ARID1B

6.58e-04175203int:TLX1
InteractionARID1B interactions

NCOA3 ARID1B PAX7

6.80e-04177203int:ARID1B
InteractionGAST interactions

CP CPD

7.14e-0440202int:GAST
InteractionNKX2-1 interactions

FOXA1 NCOA2 NCOA3

7.14e-04180203int:NKX2-1
InteractionNUP35 interactions

NCOA2 NCOA3 MAML3 ARID1B

7.16e-04424204int:NUP35
InteractionALG13 interactions

NCOA2 NCOA3 ARID1B

7.49e-04183203int:ALG13
InteractionTFF1 interactions

FOXA1 NCOA3

7.50e-0441202int:TFF1
InteractionTHRB interactions

NCOA2 FOXO1 NCOA3

7.86e-04186203int:THRB
InteractionGATA3 interactions

FOXA1 NCOA3 ARID1B

7.98e-04187203int:GATA3
InteractionKLF5 interactions

NCOA2 NCOA3 ARID1B

9.01e-04195203int:KLF5
InteractionTRIM33 interactions

FOXA1 NCOA3 ARID1B SSBP4

9.17e-04453204int:TRIM33
InteractionFEV interactions

NCOA2 NCOA3 ARID1B

1.01e-03203203int:FEV
InteractionALX4 interactions

FOXA1 DLX1

1.03e-0348202int:ALX4
InteractionNR1I3 interactions

NCOA2 NCOA3

1.03e-0348202int:NR1I3
InteractionNR1I2 interactions

NCOA2 NCOA3

1.03e-0348202int:NR1I2
InteractionMEF2C interactions

NCOA2 NCOA3

1.30e-0354202int:MEF2C
InteractionRARA interactions

NCOA2 FOXO1 NCOA3

1.33e-03223203int:RARA
InteractionERG interactions

NCOA2 NCOA3 ARID1B

1.33e-03223203int:ERG
InteractionLDB2 interactions

FOXA1 SSBP4

1.40e-0356202int:LDB2
InteractionTPRX2 interactions

NCOA2 ARID1B

1.40e-0356202int:TPRX2
InteractionNFIX interactions

FOXA1 ARID1B PAX7

1.40e-03227203int:NFIX
InteractionZNF503 interactions

ARID1B PAX7

1.45e-0357202int:ZNF503
InteractionNR2F1 interactions

NCOA2 NCOA3

1.50e-0358202int:NR2F1
InteractionSSBP4 interactions

PAX7 SSBP4

1.55e-0359202int:SSBP4
InteractionFLI1 interactions

ARID1B PAX7

1.71e-0362202int:FLI1
InteractionTMEM216 interactions

NCOA2 STAM2 CPD

1.76e-03246203int:TMEM216
InteractionCRX interactions

NCOA2 NCOA3 ARID1B

1.92e-03254203int:CRX
InteractionARNT interactions

NCOA2 FOXO1 PAX7

1.95e-03255203int:ARNT
InteractionESRRA interactions

NCOA2 NCOA3

1.99e-0367202int:ESRRA
InteractionHBA1 interactions

FOXA1 FOXO1

1.99e-0367202int:HBA1
InteractionSOX2 interactions

NCOA2 NCOA3 EPS8 CP DLX1 ARID1B

2.00e-031422206int:SOX2
InteractionDCTN6 interactions

FOXA1 NCOA3

2.05e-0368202int:DCTN6
InteractionGCM1 interactions

NCOA3 ARID1B

2.05e-0368202int:GCM1
InteractionNR1H2 interactions

NCOA2 NCOA3

2.05e-0368202int:NR1H2
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

NCOA2 NCOA3

9.91e-0517162486
GeneFamilyAtaxins|Trinucleotide repeat containing

NCOA3 MAML3

2.18e-0425162775
GeneFamilyForkhead boxes

FOXA1 FOXO1

6.49e-0443162508
GeneFamilyBasic helix-loop-helix proteins

NCOA2 NCOA3

4.16e-03110162420
CoexpressionZHOU_PANCREATIC_BETA_CELL

FOXA1 FOXO1

3.03e-0511202MM1247
CoexpressionZHOU_PANCREATIC_BETA_CELL

FOXA1 FOXO1

3.03e-0511202M1863
CoexpressionGAUTAM_EYE_IRIS_CILIARY_BODY_COL9A1_HIGH_CILIARY_BODY_CELLS

PLA2R1 ZIC3 SLC9B2

6.04e-05101203M43627
CoexpressionLAKE_ADULT_KIDNEY_C21_COLLECTING_DUCT_INTERCALATED_CELLS_TYPE_B

NCOA2 FOXO1 EPS8

6.40e-05103203M39240
CoexpressionLAKE_ADULT_KIDNEY_C16_COLLECTING_SYSTEM_PRINCIPAL_CELLS_CORTEX

TOX MAML3 ARID1B

1.62e-04141203M39235
CoexpressionLAKE_ADULT_KIDNEY_C20_COLLECTING_DUCT_INTERCALATED_CELLS_TYPE_A_CORTEX

NCOA2 FOXO1 EPS8

2.03e-04152203M39239
CoexpressionLAKE_ADULT_KIDNEY_C27_VASCULAR_SMOOTH_MUSCLE_CELLS_AND_PERICYTES

EPS8 MAML3 ARID1B

2.15e-04155203M39246
CoexpressionMCBRYAN_PUBERTAL_TGFB1_TARGETS_UP

FOXA1 CP CPD

2.72e-04168203M1124
CoexpressionGSE3565_CTRL_VS_LPS_INJECTED_SPLENOCYTES_DN

TOX FOXO1 NCOA3

3.07e-04175203M6328
CoexpressionBENPORATH_NOS_TARGETS

FOXO1 ARID1B ZIC3

3.28e-04179203M14573
CoexpressionMCBRYAN_PUBERTAL_TGFB1_TARGETS_UP

FOXA1 CP CPD

3.44e-04182203MM993
CoexpressionGSE34156_NOD2_LIGAND_VS_NOD2_AND_TLR1_TLR2_LIGAND_24H_TREATED_MONOCYTE_UP

CP CPD SLC9B2

3.96e-04191203M8679
CoexpressionGU_PDEF_TARGETS_DN

FOXA1 FOXO1

4.24e-0440202M10480
CoexpressionGSE23321_EFFECTOR_MEMORY_VS_NAIVE_CD8_TCELL_UP

FOXA1 STAM2 PAX7

4.27e-04196203M8428
CoexpressionGSE22025_PROGESTERONE_VS_TGFB1_AND_PROGESTERONE_TREATED_CD4_TCELL_UP

FOXO1 PLA2R1 CPD

4.47e-04199203M8381
CoexpressionGSE21379_WT_VS_SAP_KO_CD4_TCELL_DN

FOXO1 GIMAP4 DLX1

4.47e-04199203M7511
CoexpressionGSE19923_HEB_KO_VS_HEB_AND_E2A_KO_DP_THYMOCYTE_DN

GIMAP4 NCOA3 PLA2R1

4.53e-04200203M7271
CoexpressionGSE17301_ACD3_ACD28_VS_ACD3_ACD28_AND_IFNA2_STIM_CD8_TCELL_DN

FOXO1 GIMAP4 CPD

4.53e-04200203M8040
CoexpressionGSE10273_HIGH_IL7_VS_HIGH_IL7_AND_IRF4_IN_IRF4_8_NULL_PRE_BCELL_DN

FOXO1 EPS8 SSBP4

4.53e-04200203M317
CoexpressionGSE15330_HSC_VS_LYMPHOID_PRIMED_MULTIPOTENT_PROGENITOR_UP

FOXO1 CPD COL17A1

4.53e-04200203M7018
CoexpressionGSE21063_CTRL_VS_ANTI_IGM_STIM_BCELL_16H_DN

TOX GIMAP4 STAM2

4.53e-04200203M8267
CoexpressionGSE27092_WT_VS_HDAC7_PHOSPHO_DEFICIENT_CD8_TCELL_UP

FOXA1 CP COL17A1

4.53e-04200203M8203
CoexpressionGSE13522_WT_VS_IFNAR_KO_SKING_T_CRUZI_Y_STRAIN_INF_UP

TOX NCOA3 CPD

4.53e-04200203M2933
CoexpressionGSE2770_UNTREATED_VS_IL12_TREATED_ACT_CD4_TCELL_48H_UP

NCOA2 GIMAP4 COL17A1

4.53e-04200203M6044
CoexpressionGSE7460_CTRL_VS_TGFB_TREATED_ACT_CD8_TCELL_DN

TOX FOXO1 CPD

4.53e-04200203M5679
CoexpressionGSE16451_CTRL_VS_WEST_EQUINE_ENC_VIRUS_MATURE_NEURON_CELL_LINE_DN

TOX CPD SLC9B2

4.53e-04200203M7426
CoexpressionGSE360_L_MAJOR_VS_B_MALAYI_HIGH_DOSE_MAC_UP

PLA2R1 ZIC3 COL17A1

4.53e-04200203M5247
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_k-means-cluster#5_top-relative-expression-ranked_500

FOXA1 EPS8 COL17A1

3.83e-0633203gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_500_k5
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_top-relative-expression-ranked_1000

TOX FOXA1 EPS8 DLX1 CPD PAX7 COL17A1

7.07e-06836207gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_P1_bladder_J_emap-30374_k-means-cluster#5_top-relative-expression-ranked_1000

FOXA1 EPS8 CPD COL17A1

1.40e-05161204gudmap_developingLowerUrinaryTract_P1_bladder_J_1000_k5
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_k-means-cluster#4_top-relative-expression-ranked_1000

FOXA1 EPS8 COL17A1

2.13e-0558203gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_1000_k4
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_top-relative-expression-ranked_500

TOX FOXA1 EPS8 DLX1 COL17A1

3.97e-05429205gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_500
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle F_emap-6706_k-means-cluster#2_top-relative-expression-ranked_1000

FOXA1 EPS8 COL17A1

4.26e-0573203gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle F_1000_k2
CoexpressionAtlasDevelopingLowerUrinaryTract_adult_ureter_emap-29479_top-relative-expression-ranked_100

FOXA1 CP COL17A1

5.20e-0578203gudmap_developingLowerUrinaryTract_adult_ureter_100
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle_emap-6706_top-relative-expression-ranked_1000

TOX FOXA1 DLX1 CPD COL17A1 SLC9B2

5.55e-05769206gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle_1000
CoexpressionAtlasFacebaseRNAseq_e9.5_Maxillary Arch_top-relative-expression-ranked_1000_k-means-cluster#4

TOX DLX1 ZIC3 SSBP4

5.86e-05232204Facebase_RNAseq_e9.5_Maxillary Arch_1000_K4
CoexpressionAtlaskidney_adult_Mesangium_Meis_top-relative-expression-ranked_1000

TOX GIMAP4 EPS8 CP PLA2R1 CPD

1.11e-04872206gudmap_kidney_adult_Mesangium_Meis_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_P1_ureter_emap-30363_k-means-cluster#1_top-relative-expression-ranked_100

FOXA1 CP

1.43e-0419202gudmap_developingLowerUrinaryTract_P1_ureter_100_k1
CoexpressionAtlasalpha beta T cells, T.4FP3+25+.Sp, 4+ 8- GFP+ 25+, Spleen, avg-3

TOX FOXO1 GIMAP4 NCOA3

2.67e-04344204GSM399365_500
CoexpressionAtlasDevelopingLowerUrinaryTract_adult_ureter_emap-29479_top-relative-expression-ranked_200

FOXA1 CP COL17A1

3.54e-04149203gudmap_developingLowerUrinaryTract_adult_ureter_200
CoexpressionAtlasfacebase_RNAseq_e14.5_palate_poster_proximal_ERK2_WT_2500_K1

FOXA1 GIMAP4 COL17A1

3.61e-04150203facebase_RNAseq_e14.5_palate_poster_proximal_ERK2_WT_2500_K1
CoexpressionAtlasDevelopingLowerUrinaryTract_P1_ureter_emap-30363_k-means-cluster#2_top-relative-expression-ranked_200

FOXA1 CP

3.61e-0430202gudmap_developingLowerUrinaryTract_P1_ureter_200_k2
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k-means-cluster#3_top-relative-expression-ranked_200

FOXA1 COL17A1

4.37e-0433202DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k3_200
CoexpressionAtlasDevelopingLowerUrinaryTract_adult_ureter_emap-29479_top-relative-expression-ranked_1000

FOXA1 EPS8 CP CPD COL17A1

4.96e-04736205gudmap_developingLowerUrinaryTract_adult_ureter_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_top-relative-expression-ranked_500

TOX FOXA1 CPD COL17A1

5.10e-04408204DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_500
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle F_emap-6706_top-relative-expression-ranked_200

TOX DLX1 COL17A1

5.11e-04169203gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle F_200
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_top-relative-expression-ranked_200

TOX DLX1 COL17A1

5.66e-04175203gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_200
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle F_emap-6706_top-relative-expression-ranked_500

TOX FOXA1 DLX1 COL17A1

6.10e-04428204gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle F_500
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_k-means-cluster#4_top-relative-expression-ranked_200

FOXA1 COL17A1

6.12e-0439202gudmap_developingLowerUrinaryTract_e14.5_ urethra_200_k4
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_top-relative-expression-ranked_1000

TOX FOXA1 NCOA2 CPD COL17A1

7.50e-04806205gudmap_developingLowerUrinaryTract_e14.5_ urethra_1000
CoexpressionAtlasMESO-30 amniotic fluid MSC_vs_MESO-30 blastocyst-Confounder_removed-fold2.0_adjp0.05

TOX CP ARID1B ZIC3 COL17A1 SSBP4

7.63e-041245206PCBC_ratio_MESO-30 amniotic fluid MSC_vs_MESO-30 blastocyst_cfr-2X-p05
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ bladder_emap-30872_k-means-cluster#4_top-relative-expression-ranked_500

FOXA1 COL17A1

7.79e-0444202gudmap_developingLowerUrinaryTract_e14.5_ bladder_500_k4
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle F_emap-6706_top-relative-expression-ranked_1000

TOX FOXA1 EPS8 DLX1 COL17A1

9.53e-04850205gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle F_1000
CoexpressionAtlaskidney_adult_RenMedVasc_Tie2_top-relative-expression-ranked_1000

FOXO1 GIMAP4 NCOA3 PLA2R1 CPD

9.53e-04850205gudmap_kidney_adult_RenMedVasc_Tie2_1000
CoexpressionAtlasFacebaseRNAseq_e9.5_Maxillary Arch_top-relative-expression-ranked_500

TOX DLX1 ZIC3 SSBP4

9.59e-04483204Facebase_RNAseq_e9.5_Maxillary Arch_500
CoexpressionAtlasCD positive, CD4 Control, 4+ 8- B220-, Spleen, avg-4

TOX FOXO1 GIMAP4

9.60e-04210203GSM403995_500
CoexpressionAtlaskidney_adult_GlomCapSys_Tie2_top-relative-expression-ranked_1000

FOXO1 GIMAP4 NCOA3 PLA2R1 CPD

9.63e-04852205gudmap_kidney_adult_GlomCapSys_Tie2_1000
ToppCellParenchymal-NucSeq|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations

TOX NCOA2 MAML3 ARID1B ARHGAP44

2.31e-081982051996373bdccc55aac347d349bd22f6aad6d0c668
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TOX EPS8 CP ARHGAP44

1.30e-06186204e83718fabb057100835d3357df407f283d23fe16
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TOX EPS8 CP ARHGAP44

1.36e-061882044bdf8d49af0e9da349b16e3f012e1b0eec04cc4f
ToppCellnucseq|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

NCOA2 FOXO1 MAML3 ARID1B

1.51e-06193204779276e775cb2492e8dd36436295a536084a6415
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD|renal_papilla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

TOX FOXO1 CP CPD

1.51e-06193204ca7c0a4ceb05bced90f6cdc53d278e547fb241e9
ToppCellBronchial-NucSeq|Bronchial / Cell types per location group and 10X technology with lineage, and cell group designations

TOX NCOA2 MAML3 ARID1B

1.60e-06196204ab53c742866945545a92e2e61850d63c80d9a2a6
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FOXA1 CP CPD PAX7

1.70e-061992046977f939ddbc47d4921f36c0a61a205259fe1284
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FOXA1 CP CPD PAX7

1.70e-06199204fbd39d34636137d1b877dd8815d58f124990136b
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-Vein|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

FOXO1 GIMAP4 EPS8 CPD

1.74e-062002047eb366b2c5394af7c77650bde6261e7dac67154e
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)-Club_(nasal)_L.0.2.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FOXA1 CP CPD PAX7

1.74e-062002048c4c396e99be6131a8fa60d86214d561031b12bf
ToppCellNeuronal-Inhibitory-iA-iA_1(SST_PAX6)|Neuronal / cells hierarchy compared to all cells using T-Statistic

FOXO1 EPS8 MAML3 DLX1

1.74e-06200204d0167f96314be78b6d867bbcc6e4396071d931b8
ToppCellNeuronal-Inhibitory-iA-iA_1(SST_PAX6)-PAX6|Neuronal / cells hierarchy compared to all cells using T-Statistic

FOXO1 EPS8 MAML3 DLX1

1.74e-062002048a8f9d9e5ffab3f736c4bd0a5bb616d442d137d1
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FOXA1 CP ARHGAP44

2.77e-051332035bf5e654653e2c340891f51e3f2a30441b7b6b2b
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_ALM_Cpa6_Gpr88|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

TOX FOXO1 SLC9B2

3.37e-0514220384742a7e35bab09ee1cca80cfe120b613d6aed6a
ToppCellAdult-Epithelial-basal_cell-D122|Adult / Lineage, Cell type, age group and donor

FOXA1 CP COL17A1

4.30e-0515420338d346402417960044ae999e61f0092b46f2b591
ToppCelldroplet-Kidney-KIDNEY-30m-Lymphocytic-nan|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TOX GIMAP4 DLX1

5.56e-051682031fabb2455ce15315f19f01ea9308bc9e453cc095
ToppCellCOVID-19-Heart-Neuronal|Heart / Disease (COVID-19 only), tissue and cell type

TOX FOXO1 DLX1

6.07e-051732036fb5f9e6536a5d57fd8e6657b494047a2d0bc9c7
ToppCellLPS-antiTNF-Lymphocytic_NKT-iNKT/MAIT|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TOX GIMAP4 SSBP4

6.17e-0517420361aa89b56ebda0eba1ba675d5f036992967f670f
ToppCellBasal_cells-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

NCOA2 CP COL17A1

6.17e-05174203a0060be3940043015dcc49a5157de5541aed24a1
ToppCellLPS-antiTNF-Lymphocytic_NKT-iNKT/MAIT-iNKT-MAIT|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TOX GIMAP4 SSBP4

6.28e-0517520398cb577df466700e72d1bbc6689205ccf2e7fcba
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6-Inh_L1_PAX6_GRIP2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

EPS8 MAML3 DLX1

6.28e-051752030c648e7f67ffbe3b476a2ca77d246554f8cd1882
ToppCellFetal_29-31_weeks-Epithelial-club_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FOXA1 EPS8 CP

6.39e-051762033bbac5c2397535631fce8fa98f6ddb4fe0260351
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Hematologic|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GIMAP4 CP ARHGAP44

6.61e-051782030f5cf34609df791c8baebfdc6590f6eb4dbe0509
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Hematologic-hematopoietic_stem_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GIMAP4 CP ARHGAP44

6.61e-05178203d9eba884e18a0c89bdc70c194bfe4d62cca164fa
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Hematologic-hematopoietic_stem_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GIMAP4 CP ARHGAP44

6.61e-05178203b03aa1de9d20895ebad55f6fcd6fe7a49335db5a
ToppCellLPS_only-Lymphocytic_NKT-iNKT/MAIT|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TOX GIMAP4 SSBP4

6.72e-05179203de3ddc1264e43727be50d69b81cc84a3c91812a2
ToppCellLPS_only-Lymphocytic_NKT-iNKT/MAIT-iNKT-MAIT|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TOX GIMAP4 SSBP4

6.72e-05179203def981e97e3ff9019910c9af3861ca0d08eb0d0f
ToppCellCOPD-Lymphoid-T_Regulatory|World / Disease state, Lineage and Cell class

TOX NCOA2 FOXO1

6.83e-0518020351a12fbad5fa7bb12e6d616a02ff9b5141e2b063
ToppCellRA-16._Neuronal|RA / Chamber and Cluster_Paper

TOX FOXO1 DLX1

6.83e-051802035842febfdabac61ce970254fb0ef17a628f1b8c0
ToppCelldroplet-Liver-Npc-21m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GIMAP4 NCOA3 PLA2R1

7.06e-05182203dc55de945c6f78f32eb3a1b3520835eb8417e068
ToppCelldroplet-Liver-Npc-21m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GIMAP4 NCOA3 PLA2R1

7.06e-05182203010a7364da46101cb5068891fd7bc712ea8f13bd
ToppCelldroplet-Liver-Npc-21m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GIMAP4 NCOA3 PLA2R1

7.06e-05182203b1ec2015aad1181eac1bbf8d48ad6f2f7ed24a01
ToppCellNS-critical-d_0-4-Lymphoid-Treg|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

TOX FOXO1 GIMAP4

7.17e-05183203f478dfa231fc1b12ead0183cc9d22077cdf43d1f
ToppCellControl-Epithelial_cells-Airway_goblet|Control / group, cell type (main and fine annotations)

CP PLA2R1 COL17A1

7.29e-05184203d92a71441e4e19f8c301999d8186f8e48e3cd162
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_ADARB2_ADAM33|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FOXO1 EPS8 MAML3

7.41e-05185203487fa382232564f075960899d50afa0edae5d258
ToppCellfacs-Thymus-Epithelium-24m-Mesenchymal-fibroblast|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CP DLX1 ARHGAP44

7.41e-05185203eaa54b76743628c89b4310be57b87fa92b75fd37
ToppCellfacs-Thymus-Epithelium-24m-Mesenchymal-fibroblast|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CP DLX1 ARHGAP44

7.41e-05185203f7f4c921d248c637351e2e882589b99ba7f04b66
ToppCellfacs-Thymus-Epithelium-24m-Mesenchymal|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CP DLX1 ARHGAP44

7.41e-05185203ff38a15af3dec36d9993f06623591872b5d1da9a
ToppCellCOVID-19-Epithelial_cells-Airway_club|COVID-19 / group, cell type (main and fine annotations)

EPS8 CP ARHGAP44

7.41e-05185203cfe6fd73d817e173fe803bc1683c291d9bcb8608
ToppCellCOPD-Lymphoid-T_Regulatory|COPD / Disease state, Lineage and Cell class

TOX NCOA2 FOXO1

7.41e-05185203846403edd4c8f646201d519055198fc38b7ffff9
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FOXA1 EPS8 ARHGAP44

7.53e-051862032ea5ff14861e5f91d0e6a5767c403a24045d715c
ToppCell343B-Lymphocytic-CD4_T-cell-Treg_cell_4|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

TOX FOXA1 FOXO1

7.53e-05186203bca5215d406f1785bf3a420201d5686071fcaca5
ToppCellpdx|World / Sample and Cell Type and Tumor Cluster (all cells)

NCOA3 MAML3 ARID1B

7.53e-05186203de8e538c8767d41b8a52f5e58ba1affd4e7244c4
ToppCellpdx-Tumor_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

NCOA3 MAML3 ARID1B

7.53e-051862030b88a87158a9ca8de3bf40a4ff1687150707a5f0
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

EPS8 MAML3 DLX1

7.65e-05187203d2ffb2f34f07b0dd5d3cb3ee0275f46ebecf4146
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_ADARB2_ADAM33|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FOXO1 EPS8 MAML3

7.65e-0518720302105c82a9ba79d2f19e002188377fc3440770c2
ToppCellCOVID-19-kidney-Fibroblast-1|COVID-19 / Disease (COVID-19 only), tissue and cell type

EPS8 CP PLA2R1

7.65e-0518720376bfe8c42430a230a8bdf299575c444fb7780f24
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2-D175|Adult / Lineage, Cell type, age group and donor

TOX EPS8 ARHGAP44

7.77e-05188203ec38def1fdbb34ed9b30244806975bd5a4370164
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6-Inh_L1_PAX6_CA4|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FOXO1 MAML3 DLX1

7.77e-05188203ee572246e0c2f41bdbc29a03edc67b831af95c09
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-6_LAMP5_CA13_(Lamp5_Lhx6_1)|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TOX EPS8 PLA2R1

7.77e-051882033139540a656c0436b2123ea50741ff8d00112165
ToppCellCOVID-19-lung-Secretory|lung / Disease (COVID-19 only), tissue and cell type

EPS8 CP COL17A1

7.89e-0518920384d48e3ed25bebb8bb8074b3a2c5e2e88cff7f25
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-6_LAMP5_CA13_(Lamp5_Lhx6_1)|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TOX FOXO1 EPS8

8.02e-051902032f54da2bee411f8868348a4c37034184b8f58a89
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CP CPD PAX7

8.02e-051902036ea9fa08bd97bedcb21d3654467e7f8dd74c8fd0
ToppCellCOPD-Lymphoid-T_Regulatory|Lymphoid / Disease state, Lineage and Cell class

TOX NCOA2 FOXO1

8.14e-051912033ae18bc4e3dff49b5d5958da8ebc3f747274b69c
ToppCellfacs-Marrow-B-cells-3m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOXO1 EPS8 ARID1B

8.14e-051912034aa29337f4d2528577bb90dc4abfb6eab93e120f
ToppCellCOVID-19-lung-AT2|lung / Disease (COVID-19 only), tissue and cell type

TOX EPS8 ARHGAP44

8.14e-05191203276455a64c2c3503d5048615762eb2ee37f0ac70
ToppCellfacs-Marrow-B-cells-3m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOXO1 EPS8 ARID1B

8.14e-05191203318323a12029a7992f16382cb0c186f5b2e1ca47
ToppCellCOVID-19-Heart-EC_(POSTN)|Heart / Disease (COVID-19 only), tissue and cell type

CP PLA2R1 CPD

8.27e-05192203c0c34785a7bdf461722029b322e9184e3d9b3c26
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

TOX EPS8 ARHGAP44

8.27e-05192203cc9911e182a289779a2612bc213daae5607689e7
ToppCellCOVID-19-lung-Secretory|COVID-19 / Disease (COVID-19 only), tissue and cell type

FOXA1 CP COL17A1

8.27e-0519220359261098ccb52306f837f632ebaea45b90ad30fe
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

TOX EPS8 ARHGAP44

8.27e-05192203fb2f0e897228f808d9ff734ad05e9b49dc38fa50
ToppCellNS-critical-d_07-13-Epithelial-Secretory|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

FOXA1 CP PLA2R1

8.53e-051942032172d951896265243d14996eacce5aab5e14e26e
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)-Club_(nasal)_L.0.2.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FOXA1 CP PAX7

8.66e-05195203b9a1c5836eb0ca92df788c3ee093b0d9ec7b8ad9
ToppCellNS-critical-LOC-Epithelial-Secretory|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

FOXA1 EPS8 CP

8.66e-05195203b0d782eeee30c797b4da9b3be29b864983fd9e71
ToppCellRA-02._Fibroblast_II|RA / Chamber and Cluster_Paper

FOXO1 EPS8 ARID1B

8.66e-051952036a02ebbeb3199447ddce64d92d8809436e040eba
ToppCellnucseq-Epithelial|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

TOX EPS8 ARHGAP44

8.66e-051952039406866f99555198a9be311fbd65751b70f35446
ToppCellNS-moderate-d_16-33-Epithelial-Secretory|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

FOXA1 CP PLA2R1

8.79e-0519620370384c1da9baed843f414cfd1403ddd586a2db07
ToppCellcritical-Epithelial-Secretory|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

FOXA1 CP PLA2R1

8.79e-051962037da687eb983a54c28ee990424cc52e01caf5f4aa
ToppCellNS-moderate-d_07-13-Epithelial-Secretory|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

FOXA1 CP PLA2R1

8.79e-0519620347930de6b47b7bf22d8dae8b7419a9cd1d22f0ea
ToppCellMS-CD4-exh_CD4|MS / Condition, Cell_class and T cell subcluster

TOX GIMAP4 CP

8.79e-05196203d0217eccaa2cbf4ce9934e9d2e0c34a7f5c1a57e
ToppCellTracheal-10x3prime_v2-Stromal-Fibroblastic-Fibro_immune_recruiting|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

NCOA3 PLA2R1 SLC9B2

8.92e-051972034edf043e8f586fd375f56485841fe992a18bf853
ToppCellAT2_cells-IPF_03|World / lung cells shred on cell class, cell subclass, sample id

EPS8 CP COL17A1

8.92e-051972035e0d222872a25bb9e9069d3dffda2844bb69874a
ToppCelldistal-Epithelial-Club-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FOXA1 EPS8 CP

9.06e-0519820377c7fa7626ea35cb50de9c2f2df637d22e77d3fe
ToppCelldistal-2-Epithelial-Club|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FOXA1 EPS8 CP

9.06e-051982033055c03896fbfac82a3072e51c0c54d68131cf1a
ToppCellNS-critical-LOC-Epithelial-Secretory_LYPD2|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

FOXA1 EPS8 CP

9.06e-051982034a481e1edb80b950c823ed926842cd5132cfb27f
ToppCellmedial-Epithelial-Club|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FOXA1 EPS8 CP

9.06e-05198203a861cf5bb1950ed5f0363b8a834a1c246e151389
ToppCellParenchymal-10x5prime-Epithelial-Epi_airway_secretory-Secretory_Club|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

FOXA1 CP PAX7

9.06e-051982035d57acbe0d245f8bd217eeea07af060092898fbd
ToppCellmedial-2-Epithelial-Club|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FOXA1 EPS8 CP

9.06e-051982037f59d949190c10af13cbd13f81a795483deb9d14
ToppCellmedial-Epithelial-Club-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FOXA1 EPS8 CP

9.06e-05198203da7881351a71cde926325ab3e22d772f64cfab80
ToppCellPSB-critical-LOC-Epithelial|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

FOXA1 EPS8 CP

9.19e-0519920358dcb0eedafa8629585dc99e53147e2287f49689
ToppCellcellseq2-Epithelial|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

FOXA1 CP CPD

9.19e-051992032d4fb558845764f937efaf39962caaeb2c85478b
ToppCellNS-control-d_0-4-Epithelial-Secretory|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CP PLA2R1 CPD

9.19e-0519920332bdfff40fd442b88489c8b0f79af3927a51a03c
ToppCellNS-critical-d_07-13-Epithelial|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

FOXA1 EPS8 CP

9.19e-05199203b88a81cd2a89f4d27100c96ae4324dcee68daf83
ToppCellParenchymal-NucSeq-Epithelial-Epi_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TOX EPS8 ARHGAP44

9.19e-051992038587bd98de7767a575088afbea07a1feb4516b9b
ToppCellTracheal-NucSeq|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations

NCOA2 MAML3 ARID1B

9.19e-0519920394b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCellcritical-Epithelial|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

FOXA1 EPS8 CP

9.19e-05199203bbb44e2a52f102a6d891ead6c06d6c07221abd33
ToppCellParenchymal-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TOX EPS8 ARHGAP44

9.19e-051992035cea0d9e261903e0eaad60c28a07dff72ce65027
ToppCellNS-critical-d_16-33-Epithelial|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

FOXA1 EPS8 CP

9.19e-051992033b68197ec01c5f2b315d9e9b6eb02d5f6b5b77a3
ToppCellcellseq2-Epithelial-Epithelial_Glandular|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

FOXA1 CP CPD

9.19e-05199203ca78fd6e310232b25b864ed02ff9242fe1aa8206
ToppCellcontrol-Epithelial-Secretory|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CP PLA2R1 CPD

9.19e-051992033d01f90ffd271ca00129192787e4921bdca7e01e
ToppCellcontrol-Epithelial-Secretory|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CP PLA2R1 CPD

9.19e-05199203262e5b8a52c8ddb0b47048c786e8bdb7158e1b9a
ToppCellNS-critical-LOC-Epithelial|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

FOXA1 EPS8 CP

9.19e-05199203d64adb68502be596ce55fb2cb63fe1cfa2c5f8ba
ToppCellNS-moderate-d_16-33-Epithelial|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

FOXA1 EPS8 CP

9.19e-05199203aa2b51940115c22768c0d7493b4b60d41df3f376
ToppCelldistal-2-Epithelial|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FOXA1 EPS8 CP

9.33e-052002032fc1e95706f212bf18ecdf6eb5b3182ac98c9b52
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FOXA1 CP CPD

9.33e-05200203b68d212159b9d04866ba02ff55c35be247805eec
ToppCellNeuronal-Inhibitory-iA-iA_1(SST_PAX6)-SST|Neuronal / cells hierarchy compared to all cells using T-Statistic

FOXO1 EPS8 MAML3

9.33e-0520020353d5e427f0cbf5cf0b63efe4ec01da302f555704
ToppCellNeuronal-Inhibitory-iA-iA_1(SST_PAX6)-SST-MC4R|Neuronal / cells hierarchy compared to all cells using T-Statistic

FOXO1 EPS8 MAML3

9.33e-05200203c1797542541747b524c9c22c723d24c8d027d486
ToppCellTracheal-10x5prime-Epithelial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

FOXA1 CP COL17A1

9.33e-05200203efd461c687155c84ef590352207e6fe4ba392a90
ToppCelldistal-Epithelial|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FOXA1 EPS8 CP

9.33e-052002030a97080f694738bb882787cee21b91a4d5757b7a
ToppCellNeuronal-Inhibitory-iA-iA_1(SST_PAX6)-SST-MC4R-L1-2|Neuronal / cells hierarchy compared to all cells using T-Statistic

FOXO1 EPS8 MAML3

9.33e-05200203a0cc84add181109bb66ba9d49c732e1790222c96
Drugbutamben

NCOA2 NCOA3

1.10e-056202ctd:C004605
Drugirinotecan HCl; Down 200; 100uM; MCF7; HT_HG-U133A

NCOA2 NCOA3 EPS8 STAM2

1.77e-051832047498_DN
DrugKetanserin tartrate hydrate [83846-83-7]; Up 200; 7uM; HL60; HG-U133A

NCOA3 MAML3 STAM2 CPD

2.41e-051982041593_UP
Drug2-(3-hydroxypropoxy)-1,25-dihydroxyvitamin D3

NCOA2 NCOA3

4.01e-0511202ctd:C061137
Drugdihydroxy-vitamin D3

NCOA2 NCOA3

5.68e-0513202ctd:C118756
DrugN-methylmorpholine

TOX NCOA2 STAM2

8.11e-0597203CID000007972
Drugferutinin

NCOA2 NCOA3

8.73e-0516202CID000354654
Drug3-hydroxyflavone

NCOA2 NCOA3

2.93e-0429202ctd:C041477
Drugxanthan

EPS8 CP

4.54e-0436202CID000007107
Druggeldanamycin; Up 200; 1uM; MCF7; HG-U133A

NCOA2 MAML3 CPD

5.18e-04182203593_UP
DrugAsbestos, Crocidolite

FOXO1 NCOA3 EPS8 CP MAML3 ARID1B

5.18e-041241206ctd:D017638
DrugBetamethasone [378-44-9]; Up 200; 10.2uM; HL60; HG-U133A

NCOA3 MAML3 CPD

5.27e-041832031590_UP
Drugtestosterone-3-carboxymethyloxime-bovine serum albumin conjugate

NCOA2 FOXO1 CP

5.43e-04185203ctd:C045037
Drugmedrol

CP ZIC3 COL17A1

5.52e-04186203CID000004159
DrugHarmaline hydrochloride dihydrate [6027-98-1]; Down 200; 14uM; MCF7; HT_HG-U133A

NCOA2 STAM2 CPD

5.70e-041882032805_DN
DrugCorticosterone [50-22-6]; Up 200; 11.6uM; HL60; HT_HG-U133A

NCOA2 STAM2 CPD

5.78e-041892031307_UP
DrugAcetohexamide [968-81-0]; Up 200; 12.4uM; PC3; HT_HG-U133A

TOX CPD ARHGAP44

6.05e-041922031829_UP
Drug11-deoxy-16,16-dimethyl Prostaglandin E2; Down 200; 10uM; PC3; HT_HG-U133A

NCOA2 FOXO1 STAM2

6.24e-041942037538_DN
DrugOxolinic acid [14698-29-4]; Up 200; 15.4uM; HL60; HG-U133A

MAML3 STAM2 CPD

6.33e-041952031419_UP
DrugHippeastrine hydrobromide [22352-41-6]; Down 200; 10uM; HL60; HT_HG-U133A

NCOA2 NCOA3 ARHGAP44

6.33e-041952032187_DN
DrugPropoxycaine hydrochloride [550-83-4]; Up 200; 12uM; PC3; HT_HG-U133A

TOX FOXO1 STAM2

6.43e-041962037155_UP
DrugOxamniquine [21738-42-1]; Down 200; 14.4uM; HL60; HT_HG-U133A

NCOA2 NCOA3 STAM2

6.43e-041962032924_DN
DrugHydroxyzine dihydrochloride [2192-20-3]; Down 200; 9uM; MCF7; HT_HG-U133A

NCOA2 FOXO1 CPD

6.43e-041962031524_DN
DrugBuflomedil hydrochloride [35543-24-9]; Down 200; 11.6uM; HL60; HT_HG-U133A

NCOA3 STAM2 CPD

6.43e-041962031338_DN
DrugEpicatechin-(-) [154-23-4]; Down 200; 13.8uM; HL60; HT_HG-U133A

FOXO1 NCOA3 ARHGAP44

6.43e-041962032160_DN
DrugChEs

STAM2 ZIC3

6.48e-0443202CID000066898
DrugMoroxidine hydrochloride [3160-91-6]; Down 200; 19.2uM; MCF7; HT_HG-U133A

NCOA2 FOXO1 CPD

6.52e-041972035304_DN
DrugSulfachloropyridazine [80-32-0]; Down 200; 14uM; PC3; HT_HG-U133A

NCOA2 NCOA3 STAM2

6.52e-041972033769_DN
DrugEtofenamate [30544-47-9]; Down 200; 10.8uM; PC3; HT_HG-U133A

TOX FOXO1 STAM2

6.52e-041972033989_DN
DrugE)-4-hydroxytamoxifen

NCOA2 FOXO1 NCOA3

6.52e-04197203CID000063062
Drug16, 16-dimethylprostaglandin E2 methyl acetate solution; Down 200; 10uM; MCF7; HT_HG-U133A

NCOA2 STAM2 CPD

6.52e-041972036597_DN
DrugAzaperone [1649-18-9]; Down 200; 12.2uM; MCF7; HT_HG-U133A

NCOA2 FOXO1 CPD

6.52e-041972037231_DN
DrugKetotifen fumarate [34580-14-8]; Up 200; 9.4uM; MCF7; HT_HG-U133A

MAML3 STAM2 CPD

6.52e-041972037199_UP
DrugCarisoprodol [78-44-4]; Down 200; 15.4uM; HL60; HT_HG-U133A

NCOA2 NCOA3 STAM2

6.52e-041972031314_DN
DrugMephenesin [59-47-2]; Up 200; 22uM; HL60; HT_HG-U133A

NCOA2 NCOA3 ZIC3

6.62e-041982032342_UP
DrugPhenelzine sulfate [156-51-4]; Up 200; 17uM; PC3; HT_HG-U133A

STAM2 ARHGAP44 COL17A1

6.62e-041982033802_UP
DrugDrofenine hydrochloride [548-66-3]; Down 200; 11.4uM; HL60; HT_HG-U133A

NCOA2 FOXO1 ARHGAP44

6.62e-041982032714_DN
DrugTelenzepine dihydrochloride [147416-96-4]; Up 200; 9uM; HL60; HT_HG-U133A

FOXO1 NCOA3 COL17A1

6.72e-041992032388_UP
DrugLY 294002; Up 200; 10uM; HL60; HT_HG-U133A

FOXO1 GIMAP4 COL17A1

6.72e-041992036186_UP
Drugnordihydroguaiaretic acid; Down 200; 1uM; HL60; HT_HG-U133A

NCOA2 FOXO1 STAM2

6.72e-041992032683_DN
Drugestradiol, USP; Down 200; 0.01uM; MCF7; HT_HG-U133A

NCOA2 STAM2 CPD

6.82e-042002031666_DN
DrugAcenocoumarol [152-72-7]; Up 200; 11.4uM; PC3; HT_HG-U133A

NCOA3 STAM2 CPD

6.82e-042002032077_UP
DrugAndrostenedione

NCOA2 NCOA3

7.09e-0445202ctd:D000735
Drug2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane

NCOA2 NCOA3 CP

7.43e-04206203ctd:C404910
Drugpanobinostat

TOX FOXO1 STAM2 PAX7 ZIC3 SLC9B2

7.58e-041333206ctd:C496932
DrugUF-1

STAM2 ZIC3

7.74e-0447202CID000008572
Drugglyphosate

FOXA1 DLX1 PAX7

8.41e-04215203CID000003496
Diseasealveolar rhabdomyosarcoma (is_implicated_in)

FOXO1 PAX7

1.31e-063202DOID:4051 (is_implicated_in)
DiseaseAlveolar rhabdomyosarcoma

FOXO1 PAX7

1.31e-063202cv:C0206655
DiseaseRHABDOMYOSARCOMA 2

FOXO1 PAX7

1.31e-063202268220
DiseaseAlveolar rhabdomyosarcoma

FOXO1 PAX7

4.36e-065202C0206655
Diseaseprostate cancer (is_marker_for)

NCOA2 FOXO1 NCOA3

1.55e-04156203DOID:10283 (is_marker_for)
DiseaseBreast adenocarcinoma

FOXA1 ARID1B

3.52e-0441202C0858252
DiseaseNeoplasm of uncertain or unknown behavior of breast

FOXA1 ARID1B

3.52e-0441202C0496956
DiseaseBreast Carcinoma

FOXA1 NCOA2 NCOA3 ARID1B

4.20e-04538204C0678222
DiseaseProstatic Neoplasms

FOXA1 NCOA2 FOXO1 NCOA3

6.98e-04616204C0033578
DiseaseMalignant neoplasm of prostate

FOXA1 NCOA2 FOXO1 NCOA3

6.98e-04616204C0376358
Diseasecannabis dependence

TOX MAML3

3.74e-03135202EFO_0007191
Diseaselung non-small cell carcinoma (is_implicated_in)

NCOA2 ARID1B

3.96e-03139202DOID:3908 (is_implicated_in)
Diseasestomach cancer (is_marker_for)

FOXA1 NCOA2

4.13e-03142202DOID:10534 (is_marker_for)

Protein segments in the cluster

PeptideGeneStartEntry
PAGSSMGTYHNNMTT

COL17A1

226

Q9UMD9
GLMASSSPYSQPMNN

ARID1B

1041

Q8NFD5
PNQQMSPSPMSHGHY

DLX1

26

P56177
YSDSFMNPAAPSNHM

PAX7

361

P23759
HSMNGFMYGNQPGLT

CP

621

P00450
YSTTPTSQPGMYNMS

MAML3

861

Q96JK9
GVSCSMSPAMYQAHP

FAM169B

111

Q8N8A8
MSPAMYQAHPGNSED

FAM169B

116

Q8N8A8
SGNMTPASFNMSYAN

FOXA1

56

P55317
TYGSQASHNKMMNPS

FOXO1

506

Q12778
YANNHPSMHMGQPSC

CPD

1126

O75976
MNGHISNHPSSFGMY

EPS8

1

Q12929
SNHPSSFGMYPSQMN

EPS8

6

Q12929
MAAQYGSMSFNPSTP

GIMAP4

1

Q9NUV9
FHLQGQSPSFNSMMN

NCOA3

1126

Q9Y6Q9
STGMNYTPSMHQEAQ

SLC9B2

16

Q86UD5
NANYSSMPSPDMDPA

ARHGAP44

466

Q17R89
GNTHGMPCMFPFQYN

PLA2R1

171

Q13018
GSYSPMQDPNFHTMG

NCOA2

1146

Q15596
MQDPNFHTMGQRPSY

NCOA2

1151

Q15596
MGGNSMFSQQSPPHF

NCOA2

1361

Q15596
SPPHFGQQANTSMYS

NCOA2

1371

Q15596
AAGAQFPNYSPMNMN

ZIC3

211

O60481
MPSPGDSTNSSENMY

SSBP4

276

Q9BWG4
PMQTYPVQSHGGNYM

STAM2

391

O75886
GTQYSSHPQMAAMRP

TOX

146

O94900