Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionRNA polymerase II transcription regulatory region sequence-specific DNA binding

ZNF567 ZNF133 ZNF383 ZNF492 ZFP90 ZNF146 ZNF674 ZNF689 ZNF780B E2F7 CC2D1B ZNF217 ZNF226 ZNF232 BATF2 ZNF623 ZNF850 ZNF691 STAT1 ZNF829 ZNF19 OTP ZNF23 ZNF600 ZIK1 ZSCAN20 ZNF41 ZNF253 PITX1 ZNF724 MKX ZNF816 ZNF534 ZNF761 ZNF782 ZNF107 ZNF418 ZNF582 ZNF583 ZNF554

7.94e-14145914440GO:0000977
GeneOntologyMolecularFunctionDNA-binding transcription factor activity, RNA polymerase II-specific

ZNF133 ZNF383 ZNF492 ZFP90 ZNF146 ZNF674 ZNF689 ZNF780B E2F7 CC2D1B ZNF217 ZNF226 ZNF232 BATF2 ZNF623 ZNF850 STAT1 ZNF829 ZNF19 OTP ZNF23 ZNF600 ZIK1 ZSCAN20 ZNF41 ZNF253 PITX1 ZNF724 MKX ZNF816 ZNF534 ZNF761 ZNF782 ZNF107 ZNF418 ZNF582 ZNF583 ZNF554

6.99e-13141214438GO:0000981
GeneOntologyMolecularFunctionRNA polymerase II cis-regulatory region sequence-specific DNA binding

ZNF567 ZNF383 ZNF492 ZNF146 ZNF689 ZNF780B E2F7 CC2D1B ZNF217 ZNF226 ZNF232 BATF2 ZNF623 ZNF850 ZNF691 STAT1 ZNF829 ZNF23 ZNF600 ZIK1 ZSCAN20 ZNF41 ZNF253 PITX1 ZNF724 MKX ZNF816 ZNF534 ZNF761 ZNF782 ZNF107 ZNF418 ZNF583

4.74e-11124414433GO:0000978
GeneOntologyMolecularFunctioncis-regulatory region sequence-specific DNA binding

ZNF567 ZNF383 ZNF492 ZNF146 ZNF689 ZNF780B E2F7 CC2D1B ZNF217 ZNF226 ZNF232 BATF2 ZNF623 ZNF850 ZNF691 STAT1 ZNF829 ZNF23 ZNF600 ZIK1 ZSCAN20 ZNF41 ZNF253 PITX1 ZNF724 MKX ZNF816 ZNF534 ZNF761 ZNF782 ZNF107 ZNF418 ZNF583

8.32e-11127114433GO:0000987
GeneOntologyMolecularFunctionJUN kinase activity

MAPK8 MAPK9

1.54e-0431442GO:0004705
GeneOntologyMolecularFunctionphosphatidylinositol-3,4-bisphosphate phosphatase activity

INPP4A TPTE2

3.07e-0441442GO:0106017
GeneOntologyMolecularFunctionDNA-binding transcription repressor activity

ZFP90 E2F7 CC2D1B ZNF217 OTP MKX ZNF782 ZNF107 ZNF418

6.10e-043261449GO:0001217
HumanPhenoTactile hypersensitivity

UBA2 ITGB4 CDKL5

6.95e-066373HP:5200061
HumanPhenoMeconium stained amniotic fluid

ABCB4 ABCB11 PHIP

2.88e-059373HP:0012420
HumanPhenoMild malformation of cortical development

SIN3B SIN3A

5.13e-052372HP:0032059
DomainKRAB

ZNF567 ZNF133 ZNF383 ZNF492 ZFP90 ZNF674 ZNF689 ZNF780B ZNF214 ZNF226 ZNF850 ZNF829 ZNF19 ZNF23 ZIK1 ZSCAN20 ZNF41 ZNF253 ZNF816 ZNF534 ZNF761 ZNF782 ZNF418 ZNF582 ZNF583 ZNF554

2.36e-1836913826SM00349
DomainKRAB

ZNF567 ZNF133 ZNF383 ZNF492 ZFP90 ZNF674 ZNF689 ZNF780B ZNF214 ZNF226 ZNF850 ZNF829 ZNF19 ZNF23 ZIK1 ZSCAN20 ZNF41 ZNF253 ZNF816 ZNF534 ZNF761 ZNF782 ZNF418 ZNF582 ZNF583 ZNF554

2.52e-1837013826IPR001909
Domain-

ZNF567 ZNF133 ZNF383 ZNF492 ZFP90 ZNF146 ZNF674 ZNF689 ZNF780B ZNF214 ZNF217 ZNF226 ZNF232 ZNF623 ZNF850 ZNF691 ZNF829 ZNF19 ZNF23 ZNF600 ZIK1 ZSCAN20 ZNF41 ZNF253 ZNF816 ZNF534 ZNF761 ZNF782 ZNF107 ZNF418 ZNF582 ZNF583 ZNF554

2.97e-18679138333.30.160.60
Domainzf-C2H2

ZNF567 ZNF133 ZNF383 ZNF492 ZFP90 ZNF146 ZNF674 ZNF689 ZNF780B ZNF214 ZNF217 ZNF226 ZNF232 ZNF623 ZNF850 ZNF691 ZNF829 ZNF19 ZNF23 ZNF600 ZIK1 ZSCAN20 ZNF41 ZNF253 ZNF816 ZNF534 ZNF761 ZNF782 ZNF107 ZNF418 ZNF582 ZNF583 ZNF554

5.48e-1869313833PF00096
DomainZnf_C2H2/integrase_DNA-bd

ZNF567 ZNF133 ZNF383 ZNF492 ZFP90 ZNF146 ZNF674 ZNF689 ZNF780B ZNF214 ZNF217 ZNF226 ZNF232 ZNF623 ZNF850 ZNF691 ZNF829 ZNF19 ZNF23 ZNF600 ZIK1 ZSCAN20 ZNF41 ZNF253 ZNF816 ZNF534 ZNF761 ZNF782 ZNF107 ZNF418 ZNF582 ZNF583 ZNF554

5.72e-1869413833IPR013087
DomainKRAB

ZNF567 ZNF133 ZNF383 ZNF492 ZFP90 ZNF674 ZNF689 ZNF780B ZNF214 ZNF226 ZNF850 ZNF829 ZNF19 ZNF23 ZIK1 ZNF41 ZNF253 ZNF816 ZNF534 ZNF761 ZNF782 ZNF418 ZNF582 ZNF583 ZNF554

1.41e-1735813825PS50805
DomainZINC_FINGER_C2H2_2

ZNF567 ZNF133 ZNF383 ZNF492 ZFP90 ZNF146 ZNF674 ZNF689 ZNF780B ZNF214 ZNF217 ZNF226 ZNF232 ZNF623 ZNF850 ZNF691 ZNF829 ZNF19 ZNF23 ZNF600 ZIK1 ZSCAN20 ZNF41 ZNF253 SCAPER ZNF816 ZNF534 ZNF761 ZNF782 ZNF107 ZNF418 ZNF582 ZNF583 ZNF554

1.92e-1777513834PS50157
DomainZINC_FINGER_C2H2_1

ZNF567 ZNF133 ZNF383 ZNF492 ZFP90 ZNF146 ZNF674 ZNF689 ZNF780B ZNF214 ZNF217 ZNF226 ZNF232 ZNF623 ZNF850 ZNF691 ZNF829 ZNF19 ZNF23 ZNF600 ZIK1 ZSCAN20 ZNF41 ZNF253 SCAPER ZNF816 ZNF534 ZNF761 ZNF782 ZNF107 ZNF418 ZNF582 ZNF583 ZNF554

2.07e-1777713834PS00028
DomainZnf_C2H2-like

ZNF567 ZNF133 ZNF383 ZNF492 ZFP90 ZNF146 ZNF674 ZNF689 ZNF780B ZNF214 ZNF217 ZNF226 ZNF232 ZNF623 ZNF850 ZNF691 ZNF829 ZNF19 ZNF23 ZNF600 ZIK1 ZSCAN20 ZNF41 ZNF253 SCAPER ZNF816 ZNF534 ZNF761 ZNF782 ZNF107 ZNF418 ZNF582 ZNF583 ZNF554

4.31e-1779613834IPR015880
DomainZnf_C2H2

ZNF567 ZNF133 ZNF383 ZNF492 ZFP90 ZNF146 ZNF674 ZNF689 ZNF780B ZNF214 ZNF217 ZNF226 ZNF232 ZNF623 ZNF850 ZNF691 ZNF829 ZNF19 ZNF23 ZNF600 ZIK1 ZSCAN20 ZNF41 ZNF253 SCAPER ZNF816 ZNF534 ZNF761 ZNF782 ZNF107 ZNF418 ZNF582 ZNF583 ZNF554

6.06e-1780513834IPR007087
DomainZnF_C2H2

ZNF567 ZNF133 ZNF383 ZNF492 ZFP90 ZNF146 ZNF674 ZNF689 ZNF780B ZNF214 ZNF217 ZNF226 ZNF232 ZNF623 ZNF850 ZNF691 ZNF829 ZNF19 ZNF23 ZNF600 ZIK1 ZSCAN20 ZNF41 ZNF253 SCAPER ZNF816 ZNF534 ZNF761 ZNF782 ZNF107 ZNF418 ZNF582 ZNF583 ZNF554

6.78e-1780813834SM00355
DomainKRAB

ZNF567 ZNF133 ZNF383 ZNF492 ZFP90 ZNF674 ZNF689 ZNF780B ZNF214 ZNF226 ZNF850 ZNF829 ZNF19 ZIK1 ZNF41 ZNF253 ZNF816 ZNF534 ZNF761 ZNF782 ZNF418 ZNF582 ZNF583 ZNF554

1.69e-1635813824PF01352
Domainzf-C2H2_6

ZNF567 ZNF133 ZNF492 ZFP90 ZNF780B ZNF850 ZNF600 ZNF253 ZNF816 ZNF761 ZNF782 ZNF107 ZNF418 ZNF582 ZNF554

1.18e-0831413815PF13912
DomainHDAC_interact

SIN3B SIN3A

5.42e-0521382SM00761
DomainSin3_C

SIN3B SIN3A

5.42e-0521382IPR031693
DomainDUF1712

CCZ1B CCZ1

5.42e-0521382PF08217
DomainSin3_corepress

SIN3B SIN3A

5.42e-0521382PF08295
DomainSin3a_C

SIN3B SIN3A

5.42e-0521382PF16879
DomainHDAC_interact_dom

SIN3B SIN3A

5.42e-0521382IPR013194
DomainDUF1712_fun

CCZ1B CCZ1

5.42e-0521382IPR013176
DomainDUF4599

SPATA31E1 SPATA31D4 SPATA31D3

8.27e-05121383PF15371
DomainDUF4599

SPATA31E1 SPATA31D4 SPATA31D3

8.27e-05121383IPR027970
DomainPAH

SIN3B SIN3A

1.62e-0431382IPR003822
Domain-

SIN3B SIN3A

1.62e-04313821.20.1160.11
DomainCHD_N

CHD3 CHD4

1.62e-0431382IPR012958
DomainCHD_C2

CHD3 CHD4

1.62e-0431382IPR012957
DomainPAH

SIN3B SIN3A

1.62e-0431382PS51477
DomainCHDCT2

CHD3 CHD4

1.62e-0431382PF08074
DomainCHDNT

CHD3 CHD4

1.62e-0431382PF08073
DomainDUF1086

CHD3 CHD4

1.62e-0431382IPR009462
DomainDUF1087

CHD3 CHD4

1.62e-0431382IPR009463
DomainPAH

SIN3B SIN3A

1.62e-0431382PF02671
DomainDUF1087

CHD3 CHD4

1.62e-0431382PF06465
DomainDUF1086

CHD3 CHD4

1.62e-0431382PF06461
DomainDUF1087

CHD3 CHD4

1.62e-0431382SM01147
DomainDUF1086

CHD3 CHD4

1.62e-0431382SM01146
DomainAnaphylatoxin_comp_syst

C4A C4B

5.34e-0451382IPR018081
DomainAnaphylatoxn_comp_syst_dom

C4A C4B

5.34e-0451382IPR001840
DomainMAPK_JNK

MAPK8 MAPK9

5.34e-0451382IPR008351
DomainANATO

C4A C4B

1.11e-0371382SM00104
DomainANAPHYLATOXIN_2

C4A C4B

1.11e-0371382PS01178
DomainANAPHYLATOXIN_1

C4A C4B

1.11e-0371382PS01177
DomainANATO

C4A C4B

1.11e-0371382PF01821
DomainAnaphylatoxin/fibulin

C4A C4B

1.11e-0371382IPR000020
DomainMacrogloblnA2_thiol-ester-bond

C4A C4B

1.47e-0381382IPR019565
DomainThiol-ester_cl

C4A C4B

1.47e-0381382PF10569
DomainMacrogloblnA2_CS

C4A C4B

1.47e-0381382IPR019742
DomainA2M

C4A C4B

2.35e-03101382PF00207
DomainA2M_N_2

C4A C4B

2.35e-03101382IPR011625
DomainA2M_comp

C4A C4B

2.35e-03101382IPR011626
DomainA2M_recep

C4A C4B

2.35e-03101382PF07677
DomainA2M_comp

C4A C4B

2.35e-03101382PF07678
DomainA2M_N

C4A C4B

2.35e-03101382PF01835
DomainA2M_N

C4A C4B

2.35e-03101382IPR002890
DomainA-macroglobulin_rcpt-bd

C4A C4B

2.35e-03101382IPR009048
DomainALPHA_2_MACROGLOBULIN

C4A C4B

2.35e-03101382PS00477
DomainA2M_N_2

C4A C4B

2.35e-03101382PF07703
DomainMacroglobln_a2

C4A C4B

2.35e-03101382IPR001599
DomainMAPK

MAPK8 MAPK9

3.41e-03121382PS01351
DomainMAP_kinase_CS

MAPK8 MAPK9

3.41e-03121382IPR003527
DomainDual-sp_phosphatase_cat-dom

TPTE2 CDC14B PTP4A1

3.43e-03411383IPR000340
DomainDSPc

TPTE2 CDC14B PTP4A1

3.43e-03411383PF00782
DomainOAR

OTP PITX1

5.34e-03151382PF03826
DomainOAR

OTP PITX1

6.08e-03161382PS50803
DomainOAR_dom

OTP PITX1

6.08e-03161382IPR003654
DomainC345C

C4A C4B

6.85e-03171382SM00643
PathwayREACTOME_RNA_POLYMERASE_II_TRANSCRIPTION

ZNF567 ZNF133 SIN3B ZNF383 IQSEC3 ZNF492 ZFP90 FYTTD1 ZNF689 POLR2B APAF1 E2F7 ZNF214 CHD3 CHD4 SIN3A ZNF226 ZNF691 STAT1 RAD50 ZNF19 ZNF23 ZNF600 ZIK1 BRCA1 ZNF41 NR2C2AP ZNF253 ZNF724 ZNF761 ZNF782 ZNF418 ZNF582 ZNF583 ZNF554

4.74e-11138710635M734
PathwayREACTOME_GENERIC_TRANSCRIPTION_PATHWAY

SIN3B ZNF383 ZFP90 ZNF689 POLR2B ZNF780B E2F7 CHD3 CHD4 SIN3A ZNF226 ZNF850 RAD50 ZNF23 ZIK1 BRCA1 ZNF782 ZNF107 ZNF418 ZNF583

9.50e-0776810620MM14851
PathwayREACTOME_GENE_EXPRESSION_TRANSCRIPTION

SIN3B ZNF383 ZFP90 FYTTD1 ZNF689 POLR2B ZNF780B E2F7 CHD3 CHD4 SIN3A ZNF226 ZNF850 RAD50 ZNF23 ZIK1 BRCA1 ZNF782 ZNF107 ZNF418 ZNF583

2.01e-05102210621MM15436
PathwayBIOCARTA_AGR_PATHWAY

GIT2 DMD MAPK8 ARHGEF6

8.13e-05311064MM1343
PathwayBIOCARTA_AGR_PATHWAY

GIT2 DMD MAPK8 ARHGEF6

1.04e-04331064M6220
PathwayKEGG_MEDICUS_REFERENCE_EGF_EGFR_RAS_JNK_SIGNALING_PATHWAY

MAPK8 MAPK9 SOS2

1.12e-04131063M47594
Pubmed

A human MAP kinase interactome.

MAP4K3 EXPH5 CEP290 ITGB4 STAT1 MADD ZNF600 KIAA1549L PLEKHA5 C4A DMD MAPK9 ZNF418 SOS2

1.85e-084861451420936779
Pubmed

Acetylation-Mimic Mutation of TRIM28-Lys304 to Gln Attenuates the Interaction with KRAB-Zinc-Finger Proteins and Affects Gene Expression in Leukemic K562 Cells.

ZNF567 ZNF383 ZNF689 ZNF41 ZNF253 ZNF724 ZNF107 ZNF583 ZNF554

7.57e-08181145937372979
Pubmed

Human cytomegalovirus UL29/28 protein interacts with components of the NuRD complex which promote accumulation of immediate-early RNA.

SIN3B CHD3 CHD4 SIN3A

2.81e-0714145420585571
Pubmed

Macrophage-derived complement component C4 can restore humoral immunity in C4-deficient mice.

STAT1 C4A C4B

2.83e-074145312421924
Pubmed

Ikaros SUMOylation: switching out of repression.

SIN3B UBA2 CHD4 SIN3A

6.61e-0717145415767674
Pubmed

A candidate X-linked mental retardation gene is a component of a new family of histone deacetylase-containing complexes.

CHD3 CHD4 ZNF217 SIN3A

8.48e-0718145412493763
Pubmed

Analysis of the NuRD subunits reveals a histone deacetylase core complex and a connection with DNA methylation.

SIN3B CHD3 CHD4 SIN3A

8.48e-0718145410444591
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

ZNF567 SIN3B ZNF146 CHD3 CHD4 SIN3A ZNF226 HMG20A FSIP2 BRCA1 PITX1 USP48 PHIP

1.77e-066081451336089195
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

FNBP1 CCZ1B FYTTD1 MAP4K3 POLR2B CHD3 ANKRD50 ITGB4 STAT1 MADD FEM1B ZNF600 CCZ1 MKX DZIP3 ADAMTS18 ARHGEF6

3.03e-0610841451711544199
Pubmed

Jade-1S phosphorylation induced by CK1α contributes to cell cycle progression.

POLR2B CHD3 CHD4 USP16 DDX18

3.78e-0656145526919559
Pubmed

Neurons under T Cell Attack Coordinate Phagocyte-Mediated Synaptic Stripping.

STAT1 C4A C4B

3.91e-068145330173917
Pubmed

Phosphorylation of GSK-3beta by cGMP-dependent protein kinase II promotes hypertrophic differentiation of murine chondrocytes.

STAT1 MAPK8 MAPK9

1.14e-0511145318551195
Pubmed

Genetic interactions between Brca1 and Gadd45a in centrosome duplication, genetic stability, and neural tube closure.

BRCA1 MAPK8 MAPK9

1.14e-0511145315123655
Pubmed

A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.

EPS8 FYTTD1 MAP4K3 CARMIL1 SHB GPRIN3 ANKRD50 PLXNB2 PLEKHA5 DMD

1.17e-054211451036976175
Pubmed

NURD, a novel complex with both ATP-dependent chromatin-remodeling and histone deacetylase activities.

CHD3 CHD4 SIN3A

1.52e-051214539885572
Pubmed

A novel c-Jun N-terminal kinase (JNK)-binding protein WDR62 is recruited to stress granules and mediates a nonclassical JNK activation.

MAPK8 MAPK9 WDR62

1.52e-0512145319910486
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

FNBP1 SIN3B CORO1C ANXA6 UBA2 CHD3 CHD4 ZNF217 SIN3A NCAPG2 STAT1 RAD50 BRCA1 CCZ1 PITX1 NUCKS1

1.58e-0511031451634189442
Pubmed

Copy number analysis of complement C4A, C4B and C4A silencing mutation by real-time quantitative polymerase chain reaction.

C4A C4B

1.73e-052145222737222
Pubmed

Deficiency of C4 from donor or recipient mouse fails to prevent renal allograft rejection.

C4A C4B

1.73e-052145216565498
Pubmed

Complete deficiencies of complement C4A and C4B including 2-bp insertion in codon 1213 are genetic risk factors of systemic lupus erythematosus in Thai populations.

C4A C4B

1.73e-052145215998580
Pubmed

Hydrophilic bile acids prevent liver damage caused by lack of biliary phospholipid in Mdr2-/- mice.

ABCB4 ABCB11

1.73e-052145230416103
Pubmed

High-throughput analysis of the C4 polymorphism by a combination of MLPA and isotype-specific ELISA's.

C4A C4B

1.73e-052145219062096
Pubmed

Molecular analysis of a major antigenic region of the 240-kD protein of Mi-2 autoantigen.

CHD3 CHD4

1.73e-05214527560064
Pubmed

C-Jun N-terminal kinase (JNK) isoforms play differing roles in otitis media.

MAPK8 MAPK9

1.73e-052145225311344
Pubmed

Genetic inhibition or activation of JNK1/2 protects the myocardium from ischemia-reperfusion-induced cell death in vivo.

MAPK8 MAPK9

1.73e-052145216043490
Pubmed

Combined Activities of JNK1 and JNK2 in Hepatocytes Protect Against Toxic Liver Injury.

MAPK8 MAPK9

1.73e-052145226708719
Pubmed

Expression Analysis of ATP-Binding Cassette Transporters ABCB11 and ABCB4 in Primary Sclerosing Cholangitis and Variety of Pediatric and Adult Cholestatic and Noncholestatic Liver Diseases.

ABCB4 ABCB11

1.73e-052145231886153
Pubmed

Activation of innate and humoral immunity in the peripheral nervous system of ALS transgenic mice.

C4A C4B

1.73e-052145219933335
Pubmed

Functional in vivo interactions between JNK1 and JNK2 isoforms in obesity and insulin resistance.

MAPK8 MAPK9

1.73e-052145216818881
Pubmed

Structural basis for the C4d.1/C4d.2 serologic allotypes of murine complement component C4.

C4A C4B

1.73e-05214522459207
Pubmed

Antigen-induced B cell apoptosis is independent of complement C4.

C4A C4B

1.73e-052145217645767
Pubmed

Anti-DNA autoreactivity in C4-deficient mice.

C4A C4B

1.73e-052145212207352
Pubmed

Suppression of inflammatory cytokine production by carbon monoxide involves the JNK pathway and AP-1.

MAPK8 MAPK9

1.73e-052145212857751
Pubmed

JNK1, but not JNK2, is required in two mechanistically distinct models of inflammatory arthritis.

MAPK8 MAPK9

1.73e-052145221839715
Pubmed

Tetrahydroxylated bile acids improve cholestatic liver and bile duct injury in the Mdr2-/- mouse model of sclerosing cholangitis via immunomodulatory effects.

ABCB4 ABCB11

1.73e-052145235691019
Pubmed

Prevention of steatosis by hepatic JNK1.

MAPK8 MAPK9

1.73e-052145219945406
Pubmed

Complement C4A and C4B Gene Copy Number Study in Alzheimer's Disease Patients.

C4A C4B

1.73e-052145227758680
Pubmed

Hypothermia attenuates ischemia/reperfusion-induced endothelial cell apoptosis via alterations in apoptotic pathways and JNK signaling.

MAPK8 MAPK9

1.73e-052145219596001
Pubmed

Genetically determined partial complement C4 deficiency states are not independent risk factors for SLE in UK and Spanish populations.

C4A C4B

1.73e-052145222387014
Pubmed

Increased JNK in males compared with females in a rodent model of abdominal aortic aneurysm.

MAPK8 MAPK9

1.73e-052145222316675
Pubmed

c-Jun N-terminal kinase is required for metalloproteinase expression and joint destruction in inflammatory arthritis.

MAPK8 MAPK9

1.73e-052145211435459
Pubmed

Complement C4 maintains peripheral B-cell tolerance in a myeloid cell dependent manner.

C4A C4B

1.73e-052145223749435
Pubmed

Copy number variations of complement component C4 are associated with Behçet's disease but not with ankylosing spondylitis associated with acute anterior uveitis.

C4A C4B

1.73e-052145223918728
Pubmed

Molecular genetics of androgen-dependent and -independent expression of mouse sex-limited protein.

C4A C4B

1.73e-05214523037333
Pubmed

BSEP and MDR3: Useful Immunohistochemical Markers to Discriminate Hepatocellular Carcinomas From Intrahepatic Cholangiocarcinomas and Hepatoid Carcinomas.

ABCB4 ABCB11

1.73e-052145226735860
Pubmed

Evidence of a role for C4 in modulating interstitial inflammation in experimental glomerulonephritis.

C4A C4B

1.73e-052145211726230
Pubmed

The JNKs differentially regulate RNA polymerase III transcription by coordinately modulating the expression of all TFIIIB subunits.

MAPK8 MAPK9

1.73e-052145219620725
Pubmed

Quantitative variations in the expression of the mouse serum antigen Ss and its sex-limited allotype Slp.

C4A C4B

1.73e-05214524216347
Pubmed

Sequence determination of the thiolester site of the fourth component of human complement.

C4A C4B

1.73e-05214526950384
Pubmed

Combined mutations of canalicular transporter proteins cause severe intrahepatic cholestasis of pregnancy.

ABCB4 ABCB11

1.73e-052145216890614
Pubmed

Visual demonstration of the organization of the human complement C4 and 21-hydroxylase genes by high-resolution fluorescence in situ hybridization.

C4A C4B

1.73e-05214528660986
Pubmed

Tissue-specific RNA processing for the complement C4 gene transcript in the H-2k mouse strain.

C4A C4B

1.73e-05214528428773
Pubmed

JNK inhibition reduces apoptosis and neovascularization in a murine model of age-related macular degeneration.

MAPK8 MAPK9

1.73e-052145223341606
Pubmed

Complement C4 deficiency--a plausible risk factor for non-tuberculous mycobacteria (NTM) infection in apparently immunocompetent patients.

C4A C4B

1.73e-052145224638111
Pubmed

Transcriptional repression of C4 complement by hepatitis C virus proteins.

C4A C4B

1.73e-052145221345967
Pubmed

c-Jun N-terminal kinase 2 (JNK2) enhances cell migration through epidermal growth factor substrate 8 (EPS8).

EPS8 MAPK9

1.73e-052145221357683
Pubmed

Defective neural tube morphogenesis and altered apoptosis in the absence of both JNK1 and JNK2.

MAPK8 MAPK9

1.73e-052145210559486
Pubmed

JNK regulates muscle remodeling via myostatin/SMAD inhibition.

MAPK8 MAPK9

1.73e-052145230072727
Pubmed

The major dermatomyositis-specific Mi-2 autoantigen is a presumed helicase involved in transcriptional activation.

CHD3 CHD4

1.73e-05214527575689
Pubmed

Restriction fragment analysis of H-2 recombinant mouse strains with crossovers between E alpha and C4 genes.

C4A C4B

1.73e-05214522572548
Pubmed

The complement component C4 of mammals.

C4A C4B

1.73e-05214522302180
Pubmed

Inhibition of JNK reduces G2/M transit independent of p53, leading to endoreduplication, decreased proliferation, and apoptosis in breast cancer cells.

MAPK8 MAPK9

1.73e-052145214724588
Pubmed

Gene CNVs and protein levels of complement C4A and C4B as novel biomarkers for partial disease remissions in new-onset type 1 diabetes patients.

C4A C4B

1.73e-052145222151770
Pubmed

C4d-positive chronic rejection: a frequent entity with a poor outcome.

C4A C4B

1.73e-052145218091514
Pubmed

Comprehensive approach to study complement C4 in systemic lupus erythematosus: Gene polymorphisms, protein levels and functional activity.

C4A C4B

1.73e-052145229080553
Pubmed

Coordination of JNK1 and JNK2 is critical for GADD45alpha induction and its mediated cell apoptosis in arsenite responses.

MAPK8 MAPK9

1.73e-052145216973625
Pubmed

Genes for murine fourth complement component (C4) and sex-limited protein (Slp) identified by hybridization to C4- and Slp-specific cDNA.

C4A C4B

1.73e-05214526589636
Pubmed

C4 Deficiency is a predisposing factor for Streptococcus pneumoniae-induced autoantibody production.

C4A C4B

1.73e-052145225339671
Pubmed

A study of association of the complement C4 mutations with systemic lupus erythematosus in the Malaysian population.

C4A C4B

1.73e-052145217728371
Pubmed

Structure and organization of the C4 genes.

C4A C4B

1.73e-05214526149580
Pubmed

Sequence heterogeneity of murine complementary DNA clones related to the C4 and C4-Slp isoforms of the fourth complement component.

C4A C4B

1.73e-05214526149581
Pubmed

The follicular dendritic cell restricted epitope, FDC-M2, is complement C4; localization of immune complexes in mouse tissues.

C4A C4B

1.73e-052145212115608
Pubmed

Biochemistry and biology of anaphylatoxins.

C4A C4B

1.73e-05214523542363
Pubmed

c-Jun N-terminal kinase 2 suppresses pancreatic cancer growth and invasion and is opposed by c-Jun N-terminal kinase 1.

MAPK8 MAPK9

1.73e-052145233526844
Pubmed

C4 from C4-high and C4-low mouse strains have identical sequences in the region corresponding to the isotype-specific segment of human C4.

C4A C4B

1.73e-05214522387317
Pubmed

Mutations and polymorphisms in the bile salt export pump and the multidrug resistance protein 3 associated with drug-induced liver injury.

ABCB4 ABCB11

1.73e-052145217264802
Pubmed

Identification of the size and antigenic determinants of the human C4 gene by a polymerase chain-reaction-based amplification method.

C4A C4B

1.73e-052145216908004
Pubmed

Decreased expression of phosphorylated JNK in breast infiltrating ductal carcinoma is associated with a better overall survival.

MAPK8 MAPK9

1.73e-052145216381010
Pubmed

Structural studies on the murine fourth component of complement (C4). IV. Demonstration that C4 and Slp are encoded by separate loci.

C4A C4B

1.73e-05214527365238
Pubmed

 Hepatic immunohistochemistry of bile transporters in progressive familial intrahepatic cholestasis.

ABCB4 ABCB11

1.73e-052145226845599
Pubmed

The Caenorhabditis elegans sex determination protein FEM-1 is a CED-3 substrate that associates with CED-4 and mediates apoptosis in mammalian cells.

APAF1 FEM1B

1.73e-052145210764728
Pubmed

The role of ABC transporters' gene polymorphism in the etiology of intrahepatic cholestasis of pregnancy.

ABCB4 ABCB11

1.73e-052145230091450
Pubmed

Interaction between the labile binding sites of the fourth (C4) and fifth (C5) human complement proteins and erythrocyte cell membranes.

C4A C4B

1.73e-05214527391573
Pubmed

Peritubular capillary C4d deposition in lupus nephritis different from antibody-mediated renal rejection.

C4A C4B

1.73e-052145217971360
Pubmed

Clinical features of patients with homozygous complement C4A or C4B deficiency.

C4A C4B

1.73e-052145229928053
Pubmed

Protective role of c-Jun N-terminal kinase 2 in acetaminophen-induced liver injury.

MAPK8 MAPK9

1.73e-052145218586006
Pubmed

Analysis of C4 and the C4 binding protein in the MRL/lpr mouse.

C4A C4B

1.73e-052145217971229
Pubmed

Biliary transporter gene mutations in severe intrahepatic cholestasis of pregnancy: Diagnostic and management implications.

ABCB4 ABCB11

1.73e-052145229992621
Pubmed

JNK/SAPK Signaling Is Essential for Efficient Reprogramming of Human Fibroblasts to Induced Pluripotent Stem Cells.

MAPK8 MAPK9

1.73e-052145226867034
Pubmed

Genetic deficiency of C4 presenting with recurrent infections and a SLE-like disease. Genetic and immunologic studies.

C4A C4B

1.73e-05214526881182
Pubmed

β4 integrin marks interstitial myogenic progenitor cells in adult murine skeletal muscle.

ITGB4 DMD

1.73e-052145222205679
Pubmed

Partial C4 deficiency in juvenile idiopathic arthritis patients.

C4A C4B

1.73e-052145217921792
Pubmed

Complement activation and complement receptors on follicular dendritic cells are critical for the function of a targeted adjuvant.

C4A C4B

1.73e-052145221880985
Pubmed

Amino acid sequence around the thiol and reactive acyl groups of human complement component C4.

C4A C4B

1.73e-05214526978711
Pubmed

Plasma Complement 3 and Complement 4 Are Promising Biomarkers for Distinguishing NMOSD From MOGAD and Are Associated With the Blood-Brain-Barrier Disruption in NMOSD.

C4A C4B

1.73e-052145235898513
Pubmed

Jun N-terminal kinase 1 regulates epithelial-to-mesenchymal transition induced by TGF-beta1.

MAPK8 MAPK9

1.73e-052145218334556
Pubmed

Borrelia burgdorferi outer surface protein C (OspC) binds complement component C4b and confers bloodstream survival.

C4A C4B

1.73e-052145228873507
Pubmed

A pathogenic role for c-Jun amino-terminal kinase signaling in renal fibrosis and tubular cell apoptosis.

MAPK8 MAPK9

1.73e-052145217202416
Pubmed

The role of JNK in the development of hepatocellular carcinoma.

MAPK8 MAPK9

1.73e-052145221406557
Pubmed

Studies on the murine Ss protein: demonstration that the Ss protein is functionally the fourth component of complement.

C4A C4B

1.73e-0521452276882
InteractionTRIM28 interactions

ZNF567 ZNF133 ZNF383 ZNF492 ZFP90 ZNF674 CORO1C ZNF689 POLR2B APAF1 UBA2 CHD3 CHD4 SIN3A ZNF226 NCAPG2 STAT1 ZNF829 RAD50 ZNF19 ZNF600 BRCA1 ZNF41 ZNF253 ZNF724 DZIP3 SIK2 ZNF816 ZNF761 ZNF107 ZNF418 USP48 ZNF583 ZNF554

5.97e-10147414334int:TRIM28
InteractionRCOR1 interactions

FNBP1 SIN3B CHD3 CHD4 ZNF217 SIN3A GIT2 HMG20A RAD50 DZIP3 NUCKS1 PLEKHA5 PHIP WDR62

1.17e-0549414314int:RCOR1
CytobandEnsembl 112 genes in cytogenetic band chr19q13

ZNF567 ZNF383 ZNF146 ZNF780B UBA2 ZNF226 ZNF850 ZNF829 ZNF600 ZIK1 ZNF816 ZNF534 ZNF761 ZNF418 ZNF582 GARRE1 ZNF583 WDR62

5.28e-08119214618chr19q13
Cytoband19q13.12

ZNF567 ZNF383 ZNF850 ZNF829 WDR62

3.58e-0672146519q13.12
CytobandEnsembl 112 genes in cytogenetic band chr15q24

MAN2C1 SIN3A HMG20A NPTN SCAPER

4.67e-051221465chr15q24
Cytoband19q13.43

ZIK1 ZNF418 ZNF582 ZNF583

1.78e-0487146419q13.43
Cytoband12q24.1

CORO1C GIT2

1.03e-0315146212q24.1
Cytoband12p13.33

NRIP2 IQSEC3

1.66e-0319146212p13.33
Cytoband9q21.32

SPATA31D4 SPATA31D3

1.66e-031914629q21.32
Cytoband19p13.11

SIN3B NR2C2AP ZNF253

1.67e-0373146319p13.11
Cytoband19q13.41

ZNF600 ZNF816 ZNF534

2.01e-0378146319q13.41
Cytoband15q24

HMG20A SCAPER

2.03e-0321146215q24
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF567 ZNF133 ZNF383 ZNF492 ZFP90 ZNF146 ZNF674 ZNF689 ZNF780B ZNF214 ZNF217 ZNF226 ZNF232 ZNF623 ZNF850 ZNF691 ZNF829 ZNF19 ZNF23 ZNF600 ZIK1 ZSCAN20 ZNF41 ZNF253 SCAPER ZNF816 ZNF534 ZNF761 ZNF782 ZNF107 ZNF418 ZNF582 ZNF583 ZNF554

3.40e-217181123428
GeneFamilyX-linked mental retardation|Angiotensin receptors

ZNF674 ZNF41 DMD ARHGEF6

3.23e-04531124103
GeneFamilyRing finger proteins|Fanconi anemia complementation groups|Protein phosphatase 1 regulatory subunits|BRCA1 A complex|BRCA1 B complex|BRCA1 C complex

RAD50 BRCA1

3.76e-04511221336
GeneFamilyC3 and PZP like, alpha-2-macroglobulin domain containing

C4A C4B

1.33e-03911221234
GeneFamilyHistone deacetylases, class I|EMSY complex|NuRD complex|SIN3 histone deacetylase complex

SIN3B SIN3A

1.33e-03911221306
GeneFamilyATP binding cassette subfamily B

ABCB4 ABCB11

2.02e-03111122806
GeneFamilyHistone deacetylases, class I|EMSY complex|NuRD complex|SIN3 histone deacetylase complex

SIN3B SIN3A

2.41e-031211221243
GeneFamilyPHD finger proteins|NuRD complex

CHD3 CHD4

2.41e-031211221305
GeneFamilyMitogen-activated protein kinases

MAPK8 MAPK9

2.84e-03131122651
ToppCelltumor_Lymph_Node_/_Brain-Myeloid_cells-Activated_DCs|Myeloid_cells / Location, Cell class and cell subclass

FNBP1 FYTTD1 ANXA6 CHD3 CSF2RA PLEKHA5 USP48

2.14e-0617914675f7e6670a0e906a0a5bc75735408361d88e78fa2
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

E2F7 NCAPG2 BRCA1 NR2C2AP ZNF724 SKA3 WDR62

2.14e-06179146780112c686a8f85ad5e3cda6e3f3d3d51cf688092
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_ZNF322P1|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

EPS8 EXPH5 PTGFR LRRC3B ABCB11 PLD5 CALN1

2.30e-061811467062f00736eed96e4f4327615d093558dd7d82b20
ToppCell368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

MAN2C1 TTC16 ZNF780B SHB MAPK9 ZNF554

1.19e-051541466ba55a63cfa5e0fb9dfec794f80078a2f0d03d0ad
ToppCellCOVID-19-kidney-Technical/muscle_(Mes)|kidney / Disease (COVID-19 only), tissue and cell type

ADCY2 PLD5 DMD IQCM CDH8 CALN1

1.43e-0515914665335cbcdeaf2bbd0268bbfe0e45c8c0d288e640d
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Lsp1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

EPS8 TEX9 MYO3B PLD5 CALN1 ARHGEF6

1.64e-051631466bba830a302919c8b33f914a8839877fc21dd28a0
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF492 E2F7 NCAPG2 BRCA1 SKA3 WDR62

1.82e-0516614662642544070564debe2deb2938d2c33997bf5ef02
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling-Cycling_Connecting_Tubule_Cell_S-high|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF492 E2F7 NCAPG2 BRCA1 ZNF724 WDR62

1.89e-051671466108ae6221c6edc63c0ec42c42471b3a15a594043
ToppCelldroplet-Heart-nan-24m-Hematologic-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

E2F7 NCAPG2 ZNF691 MADD BRCA1 SKA3

1.89e-051671466bad33497ceeab968a7eb8a48b921c6f936390743
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

E2F7 SLFN14 NCAPG2 BRCA1 SKA3 WDR62

2.30e-051731466a25459b8140b0dbcb73e3b4cc1407b679229f25c
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

EPS8 MAP4K3 INPP4A GLCCI1 SHOC1 ADAMTS18

2.46e-05175146677c16e615c0fb9c83f29d7e0a547be72635fac81
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

EPS8 INPP4A GPRIN3 GLCCI1 SHOC1 ADAMTS18

2.54e-051761466c2c4306476989bc2fb30dab00250ef7915842f13
ToppCell390C-Lymphocytic-CD4_T-cell-Treg_cell_2|390C / Donor, Lineage, Cell class and subclass (all cells)

HECTD4 GPRIN3 MADD BRCA1 NR2C2AP ZNF816

2.70e-051781466829ea00c022a78d1861aa3ec53503272976775d9
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Neuronal-medium_spiny_neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPRIN3 PCNX2 KIAA1549L CLVS2 CDH8 CALN1

3.06e-051821466d41ff834b8fc1d0e23cac7ae261de5f72874e462
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Neuronal-SPN_Neuron_STR|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPRIN3 PCNX2 KIAA1549L CLVS2 CDH8 CALN1

3.06e-0518214666cde859edfe7607bd7ada89d20258413d06f4207
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_ZNF322P1|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

EPS8 EXPH5 PTGFR LRRC3B PLD5 CALN1

3.06e-051821466d3a037268f026eb2f84428b1821022503cef7756
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

EPS8 MAP4K3 INPP4A GLCCI1 SHOC1 ADAMTS18

3.46e-051861466a6ef5d5944af5689b5f27bef89cd05645eedbe50
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF492 E2F7 NCAPG2 BRCA1 SKA3 WDR62

3.89e-05190146631de1727822e9818652946dfb962daee77ffad68
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-cycling_stromal|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

E2F7 NCAPG2 KIAA1549L BRCA1 NUCKS1 SKA3

4.01e-05191146650854384fdaa0efa2e3227659d544ed09ac102f2
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_cycling-mes_proliferating2_(11)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

ZNF492 E2F7 ZNF850 NCAPG2 SKA3 WDR62

4.13e-0519214660a54c79dcfdeb99e3b512d42b22359618cfd17e9
ToppCellDividing_Macrophages-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

E2F7 NCAPG2 OTP BRCA1 SKA3 WDR62

4.13e-051921466741bd0c2b0a7ce3fcb1610ce8bdacaf9a803c212
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

ZNF492 NCAPG2 BRCA1 NR2C2AP ZNF724 SKA3

4.25e-051931466bbdfda6665941cfa1965418bb91ef9ff43b1326f
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_cycling-mes_proliferating3_(7)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

ZNF492 E2F7 NCAPG2 BRCA1 SKA3 WDR62

4.37e-051941466f9070035553bc68106a9e0bdf4b507715a138aba
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ZNF492 E2F7 NCAPG2 BRCA1 NR2C2AP ZNF724

4.50e-051951466b65463a804fed2d9a3be9e528ca8b9c98469bc86
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_cycling-mes_proliferating3_(7)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

ZNF492 E2F7 NCAPG2 BRCA1 SKA3 WDR62

4.76e-05197146684ed777cdba569200a3ef1654d8a12f17fcfb7f1
ToppCellBAL-Mild-cDC_10|Mild / Compartment, Disease Groups and Clusters

FNBP1 ANXA6 CHD3 CSF2RA PLEKHA5 DMD

4.76e-051971466c0550d41dd5619b369b590f3d6a61154dd7b2cab
ToppCellH1299-infected-SARSCoV2|infected / Cell line, Condition and Strain

CEP290 RAD50 DDX18 SCAPER PHIP MFSD10

4.76e-0519714660fa3e4cf93e77d78b1f97b906c5b13ca741ae17e
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-4M-Proliferating-cycling_dorsal_progenitors|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.

E2F7 ZNF850 NCAPG2 BRCA1 SKA3 WDR62

4.90e-051981466dada1c19a261c8e1090957cd7e37f2a43a9fe14f
ToppCell(02)_MMP9/10+-(2)_GFP_FOXI1|(02)_MMP9/10+ / shred by cell type by condition

EPS8 CEP290 USP16 GLCCI1 RAD50 NUCKS1

5.03e-05199146618a7f9ced4364f45b184bd529f32ef02c27779d3
ToppCellLPS_anti-TNF-Endothelial-Endothelial-FOXM1|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

E2F7 ZNF850 NCAPG2 BRCA1 SKA3 WDR62

5.03e-05199146698575fcce726589e93fbb4df1aab03e57cb56076
ToppCellLPS_IL1RA-Endothelial-Endothelial-FOXM1|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

E2F7 ZNF850 NCAPG2 BRCA1 SKA3 WDR62

5.03e-051991466be2276c9a1994579ba1d2998b49bf549c1324d44
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-FOXM1|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

E2F7 ZNF850 NCAPG2 BRCA1 SKA3 WDR62

5.18e-0520014664cfe08878a6981bf7b3567f9e82192d8f060ddde
ToppCellControl_saline-Endothelial-Endothelial-FOXM1|Control_saline / Treatment groups by lineage, cell group, cell type

E2F7 ZNF850 NCAPG2 BRCA1 SKA3 WDR62

5.18e-0520014669bbc7b5561151f6ff65f40b3226271def732e5d9
ToppCellLPS_IL1RA-Epithelial_airway-airway_epithelial-Ciliated|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

TTC16 ZC2HC1C TEX9 ADCY2 SLC47A2 RP1

5.18e-0520014664992dbf0514d674017315dbd20d91dfec0c608e9
ToppCellNeuronal-Inhibitory-iA-iA_3(VIP)-VIP_3-CHRM2|Neuronal / cells hierarchy compared to all cells using T-Statistic

EPS8 EXPH5 PTGFR LRRC3B PLD5 CALN1

5.18e-052001466501a3b93624df463458a35d3e6648d4ccc941724
ToppCellNeuronal-Inhibitory-iA-iA_3(VIP)-VIP_3-CHRM2-L1-3|Neuronal / cells hierarchy compared to all cells using T-Statistic

EPS8 EXPH5 PTGFR LRRC3B PLD5 CALN1

5.18e-052001466d1f36a8232411933b1494168ec912fd0e5246428
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW23-Stem_cells-Neuroepithelial_cell|GW23 / Sample Type, Dataset, Time_group, and Cell type.

E2F7 SLC47A2 ZNF600 ZNF816 SKA3 WDR62

5.18e-052001466c9c832f489629b8724501ddfede984b41a7b674d
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW23-Stem_cells|GW23 / Sample Type, Dataset, Time_group, and Cell type.

E2F7 SLC47A2 ZNF600 ZNF816 SKA3 WDR62

5.18e-052001466d7832ab1ed0ff0a6f7e3ac11b2095dc72c90af44
ToppCell(18)_cycling_gd_T|World / shred on Cell_type and subtype

E2F7 NCAPG2 BRCA1 ADAMTS18 SKA3 WDR62

5.62e-0520314667d58929058c4769226a29febee1fd8ba64bc9f1a
ToppCell368C-Fibroblasts-Fibroblast-E|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

E2F7 ZIK1 ZNF253 PLD5 WDR62

1.36e-041501465c3ad5fa41eb636a5d691c0268c0f1c32cd0de658
ToppCell368C-Fibroblasts-Fibroblast-E-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

E2F7 ZIK1 ZNF253 PLD5 WDR62

1.36e-04150146578b8029e71d26f336a46274c8afef3435bf536b9
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c06-NR4A2|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

INPP4A GRK5 SLC47A2 NR2C2AP CALN1

1.45e-0415214655adcdf93fd3ca066402aaaf308c363e4648f871d
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF217 KIAA1549L MYO3B IQCM ZNF583

1.59e-0415514658b524c65fa5c901f70c7caae4ec7fd2859eaf227
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling-Cycling_Connecting_Tubule_Cell_low-phase|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF217 KIAA1549L MYO3B IQCM ZNF583

1.59e-0415514657fe8b8c0c8a9e3190cfd52d3934509e6780e1717
ToppCell368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1.5|368C / Donor, Lineage, Cell class and subclass (all cells)

TTC16 CDC14B ZNF600 BRCA1 ZNF107

1.74e-041581465390b9c455ed15a6804613eecfd2776949dfba146
ToppCellFetal_29-31_weeks-Immune-mast_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

NRIP2 ZIK1 NR2C2AP ABCB11 ARHGEF6

1.74e-0415814650c27c475289c70b17b6a66fc71f628511c5f0ae1
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c09-GZMK-FOS_l|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ZNF689 GRK5 ZNF691 NR2C2AP MFSD10

1.79e-04159146503d77e7fee40262bf0942aab96b273f1c4f5d8e3
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Lsp1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

EPS8 GRK5 MYO3B PLD5 ARHGEF6

1.79e-0415914650dccc4275b9b4f8554dd556da7218e130bff8fd1
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

E2F7 PCNX2 SKA3 IQCM CDH8

1.79e-0415914652233fee5dcdb6c7dee5b1bd8efbc07d86b339927
ToppCellfacs-Marrow-Granulocytes-24m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TLCD4 SLFN14 BATF2 ABCB4 ZSCAN20

1.95e-0416214652787be283b7a705647058aeb9bc54006ce5ffe95
ToppCellLPS-antiTNF-Endothelial-Endothelial-FOXM1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

E2F7 NCAPG2 BRCA1 SKA3 WDR62

2.01e-0416314655285318c52aa31c9b22dc2ffff078e32e408604d
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

E2F7 NCAPG2 OTP SKA3 WDR62

2.01e-0416314653f434015c0cbefb31eeda133c34f75384c5f7e22
ToppCellfacs-Marrow-B-cells-24m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TLCD4 HECTD4 SLFN14 ABCB4 ABCB11

2.06e-04164146518eeda51e69722992c3a7f699be293535a90868b
ToppCellfacs-Pancreas-Exocrine-24m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF383 ZFP90 APAF1 PCDHB3 GIT2

2.06e-041641465b895674ed2df87db8fbfb30b7e31620945588491
ToppCell10x5'-Liver-Lymphocytic_T_CD4-Tnaive/CM_CD4_activated|Liver / Manually curated celltypes from each tissue

ZNF492 CARMIL1 CCZ1 ZNF724 GARRE1

2.18e-0416614659afa33b5ad27dc33576be592f9b22d8161366838
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c03-MKI67|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

E2F7 QRICH2 ZSCAN20 ZNF816 SKA3

2.24e-0416714659280558baddea51aae47f3383d895a9b0c6749a4
ToppCell10x5'-Lung-Lymphocytic_T_CD4/8-lo-Trm_Tgd|Lung / Manually curated celltypes from each tissue

ZNF567 ZNF146 CC2D1B ZNF829 SIK2

2.24e-041671465dcbcc658082910838c8082d71a64917055086cc4
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

E2F7 NCAPG2 BRCA1 SKA3 WDR62

2.31e-041681465d35944fd9fea9934ce1e76b2b35d48e2300cca61
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TTC16 TRPC4 RP1 DMD CDH8

2.37e-0416914658bca402e144819cb9a8d431d6bf9429be2fff6d6
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

E2F7 NCAPG2 BRCA1 SKA3 WDR62

2.37e-041691465b253a4a50c06d36228fcd5d856c57202cbac158f
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

E2F7 NCAPG2 BRCA1 ZNF724 WDR62

2.37e-0416914650bc8ef341ce307b19018d4ac8de0a4d04254209d
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling-Cycling_Distal_Convoluted_Tubule_Cell_S-high|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

E2F7 NCAPG2 BRCA1 SKA3 WDR62

2.37e-041691465e7514956b2e4298222ec443f98b2f5289451786e
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

E2F7 NCAPG2 BRCA1 SKA3 WDR62

2.37e-041691465121768fc51fc3441ec725346a1bbe29e21d05971
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.6.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CORO1C GPRIN3 QRICH2 ZNF23 ZNF724

2.44e-041701465e0429f45a3639a10294ceb492f2286c495481c2b
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HECTD4 ANKRD50 CLVS2 ADAMTS18 DMD

2.44e-0417014655570c0e825bca77613bf0ebde620cf744fa1cb84
ToppCellnucseq-Epithelial-Epithelial_Neuro-Secretory-PNEC|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PCDHB3 ADCY2 OTP PITX1 ADAMTS18

2.50e-041711465f4321133190a3df9d31f5d4021a464d3840145f1
ToppCellnucseq-Epithelial-Epithelial_Neuro-Secretory-PNEC-PNEC|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PCDHB3 ADCY2 OTP PITX1 ADAMTS18

2.50e-041711465ed4fb6c84579d99df33de5f8f928c3cd2f3d3d72
ToppCellAT1-AT2_cells-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

CHD3 ITGB4 FSIP2 MYO3B SHOC1

2.57e-0417214650be41df5d35d818deb7316ac21c9366eb4b7bfd1
ToppCellnucseq-Epithelial-Epithelial_Neuro-Secretory|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PCDHB3 ADCY2 OTP PITX1 ADAMTS18

2.57e-041721465d0cdedd734406988a9a93d7300c7b1a8b4b45c38
ToppCell10x5'-bone_marrow-Lymphocytic_NK-Cycling_NK|bone_marrow / Manually curated celltypes from each tissue

E2F7 NCAPG2 NUCKS1 SKA3 WDR62

2.64e-0417314658a9dd85f718564c07cf3120ad648daeb60c94fc5
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Mesenchymal-brain_pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UBA2 ZC2HC1C PLXNB2 DMD ARHGEF6

2.64e-0417314652415b6ff49f334da570577d4e93484d024a3dbd5
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Mesenchymal-Pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UBA2 ZC2HC1C PLXNB2 DMD ARHGEF6

2.64e-0417314652acd0693a2dfe04e3c1b2125ea63efe92d13150b
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

E2F7 NCAPG2 BRCA1 SKA3 WDR62

2.71e-04174146584da9faff088d05233183b425385beb054c92d1b
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

E2F7 NCAPG2 BRCA1 SKA3 WDR62

2.71e-041741465c26eac176e9b0cba385630fdc60e0314a4e4caac
ToppCellASK452-Immune-B_cell|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq

IQSEC3 DNAJB9 PCDHB16 ZNF816 ZNF761

2.71e-04174146569723f5666abc3af5f0431901a60246c9915ef81
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

EPS8 INPP4A GLCCI1 SHOC1 ADAMTS18

2.71e-0417414655f4436863a40f8bca46e2989bca66c02b6be88d4
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MAP4K3 INPP4A GLCCI1 SHOC1 ADAMTS18

2.79e-0417514651d8da48236549c01381f777ce5b2937f9f86acc2
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

EPS8 INPP4A GLCCI1 SHOC1 ADAMTS18

2.79e-04175146598947a226b5a2ac7091ff9d34243ea7736add973
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

EPS8 INPP4A GLCCI1 SHOC1 ADAMTS18

2.86e-04176146525ebc8716aa44e44fce577701e3e82c6745a75ab
ToppCell3'_v3-Lung-Lymphocytic_T_CD4/8-lo-Cycling_T|Lung / Manually curated celltypes from each tissue

E2F7 NCAPG2 BRCA1 SKA3 WDR62

2.86e-041761465a40dfd8c4ba16757ff929b2f03a0628acf334de4
ToppCellnormal_Pleural_Fluid-Myeloid_cells-CD163+CD14+_DCs|normal_Pleural_Fluid / Location, Cell class and cell subclass

ZNF133 PLXNB2 ADCY2 FSIP2 ZSCAN20

2.86e-0417614657a74217b7fa1032b918f00a3972dff5fab74671a
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_ZNF322P1|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

EPS8 EXPH5 PTGFR LRRC3B PLD5

2.94e-04177146584116796ca4c7007508c0f1a68a1135c7b922278
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EPS8 GRK5 TRPC4 UBA2 DMD

2.94e-041771465a8625d14682183cf77cb51eaf11bc15a3528f586
ToppCellPBMC-Convalescent-Lymphocyte-B-B_cell-B_naive-B_naive-9|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

NRIP2 ZNF691 SNX13 ABCB4 MAPK8

2.94e-041771465ae55773c531099a9e94f44f01ba48b5e71dddc53
ToppCellfacs-Lung-EPCAM-18m-Myeloid-Myeloid_Dendritic_Type_2|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FNBP1 EPS8 CSF2RA SLC45A2 ARHGEF6

2.94e-0417714653cb96d7d56c9ff90f1f8a6caaf49e580e2524c7d
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EPS8 GRK5 TRPC4 UBA2 DMD

2.94e-0417714653645e2f4a48283f290f85c49c3e79e3f58ac9aa6
ToppCellfacs-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l49|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CARMIL1 PTGFR PCDHB16 C4B SKA3

3.01e-041781465cb9a446c145b1435cfe12a1d4568aed0924a6a20
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EPS8 INPP4A GLCCI1 SHOC1 ADAMTS18

3.09e-041791465e6ae070b4c52ba08167c7d64ea4cfbac0454c1bf
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

EPS8 GLCCI1 PTP4A1 RP1 DMD

3.09e-041791465815b959ce8721c5ded70c0ca6e318dafc691746e
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

E2F7 NCAPG2 BRCA1 SKA3 WDR62

3.09e-04179146588d44b04eb5c079531db663ed98ddb20b60feb9a
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Ascending_Thin_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EXPH5 PTGFR GLCCI1 SLC47A2 RP1

3.09e-04179146555bc69f107fc710db7617c428575792adfdbbcc1
ToppCellBAL-Severe-Lymphocyte-B-B_cell-B_cell-B_activate-7|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

APAF1 TEX9 ABCB4 ZNF816 ZNF107

3.17e-0418014659f4bbaf6435c23e3e552ae22be8ea7884314192d
ToppCellBAL-Severe-Lymphocyte-B-B_cell-B_cell|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

APAF1 TEX9 ABCB4 ZNF816 ZNF107

3.17e-041801465b465f2f8b0e9a2034a4f1272bb00c77439164dbf
ToppCellBAL-Severe-Lymphocyte-B-B_cell|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

APAF1 TEX9 ABCB4 ZNF816 ZNF107

3.17e-041801465c3c72531af5b9f7a7416727fe609dab5180e03b6
ToppCellLPS-IL1RA-Endothelial-Endothelial-FOXM1|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

E2F7 NCAPG2 BRCA1 SKA3 WDR62

3.17e-041801465334e2b1f6eb7d4ece20b1c7b02107863f913237f
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

E2F7 NCAPG2 BRCA1 SKA3 WDR62

3.17e-041801465f8a15c13d85c1bbbf86ce49bb6f86c368ddf22df
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EPS8 INPP4A GLCCI1 SHOC1 ADAMTS18

3.25e-04181146530729f0364f719c044712a51453e22dc2c1a232b
ToppCellCOPD-Lymphoid-B_Plasma|Lymphoid / Disease state, Lineage and Cell class

CORO1C CARMIL1 TLCD4 C4B USP48

3.34e-04182146519db653fe04c5e2957eea1f4893b1c1fca4ddcbd
ToppCellHippocampus-Neuronal-Inhibitory|Hippocampus / BrainAtlas - Mouse McCarroll V32

ANKRD50 MYO3B MKX UBXN2A PLD5

3.34e-041821465b54ae650c04dfd0759c5f5e752b9bf684dd36516
ToppCellRA-13._Vascular_Smooth_Muscle|RA / Chamber and Cluster_Paper

FNBP1 CARMIL1 TRPC4 PLD5 DMD

3.42e-041831465818fd886e0188091310825f9145fa53328f2c979
Diseaseintellectual disability (is_implicated_in)

CDKL5 DMD ARHGEF6 WDR62

9.02e-06301304DOID:1059 (is_implicated_in)
DiseaseProgressive intrahepatic cholestasis (disorder)

ABCB4 ABCB11

5.76e-0531302C0268312
DiseaseProgressive familial intrahepatic cholestasis type 3

ABCB4 ABCB11

5.76e-0531302cv:C1865643
DiseaseCholestasis, benign recurrent intrahepatic 1

ABCB4 ABCB11

5.76e-0531302C4551899
Diseaseintrahepatic cholestasis (is_implicated_in)

ABCB4 ABCB11

1.15e-0441302DOID:1852 (is_implicated_in)
DiseaseCholestasis, progressive familial intrahepatic 1

ABCB4 ABCB11

1.15e-0441302C4551898
DiseaseEpidermolysis Bullosa

EXPH5 ITGB4

1.15e-0441302C0014527
Diseasebreast cancer (implicated_via_orthology)

STAT1 RAD50 BRCA1

1.79e-04251303DOID:1612 (implicated_via_orthology)
DiseaseEpidermolysis Bullosa Simplex

EXPH5 ITGB4

1.91e-0451302C0079298
DiseaseMental Retardation, X-Linked

ZNF674 ZNF41 ARHGEF6

2.81e-04291303C1136249
DiseaseMental Retardation, X-Linked 1

ZNF41 DMD ARHGEF6

3.77e-04321303C2931498
DiseaseProfound Mental Retardation

INPP4A SIN3A SCAPER PHIP WDR62

3.85e-041391305C0020796
DiseaseMental Retardation, Psychosocial

INPP4A SIN3A SCAPER PHIP WDR62

3.85e-041391305C0025363
DiseaseMental deficiency

INPP4A SIN3A SCAPER PHIP WDR62

3.85e-041391305C0917816
DiseaseCholestasis of pregnancy

ABCB4 ABCB11

5.30e-0481302C0268318
Diseaseinfluenza A (H1N1)

CEP290 SNX13 DDX18 DMD

6.03e-04871304EFO_1001488
Diseasecystic fibrosis (implicated_via_orthology)

ABCB4 ABCB11

6.80e-0491302DOID:1485 (implicated_via_orthology)
Diseasecholestasis (implicated_via_orthology)

ABCB4 ABCB11

6.80e-0491302DOID:13580 (implicated_via_orthology)
DiseaseIntellectual Disability

IQSEC3 INPP4A CHD3 SIN3A BRCA1 SCAPER PHIP WDR62

8.47e-044471308C3714756
Diseasetype 2 diabetes mellitus (implicated_via_orthology)

MADD FEM1B MAPK8 MAPK9

1.22e-031051304DOID:9352 (implicated_via_orthology)
DiseaseTrigeminal Neuralgia

MAPK8 MAPK9

1.24e-03121302C0040997
DiseaseSecondary Trigeminal Neuralgia

MAPK8 MAPK9

1.24e-03121302C0393787
DiseaseTrigeminal Neuralgia, Idiopathic

MAPK8 MAPK9

1.24e-03121302C0393786
Diseasedevelopmental disorder of mental health (implicated_via_orthology)

SIN3B SIN3A PLXNB2

1.33e-03491303DOID:0060037 (implicated_via_orthology)
Diseaseresponse to atorvastatin, myopathy

ADCY2 GARRE1

1.46e-03131302EFO_0004145, EFO_0010124
Diseaseserum alanine aminotransferase measurement

EXPH5 HECTD4 PLXNB2 USP16 ABCB4 NPTN ADAMTS18 ABCB11 RP1 USP48 SOS2

1.64e-0386913011EFO_0004735
DiseaseHermansky-Pudlak syndrome (implicated_via_orthology)

CCZ1B CCZ1

1.69e-03141302DOID:3753 (implicated_via_orthology)
DiseaseHereditary Breast and Ovarian Cancer Syndrome

RAD50 BRCA1

1.69e-03141302C0677776
Diseaseaspartate aminotransferase measurement

CARMIL1 HECTD4 GPRIN3 MADD SNX13 ABCB4 NPTN BRCA1 ABCB11 PHIP SOS2

2.24e-0390413011EFO_0004736
Diseasereticulocyte count

CCZ1B CORO1C HECTD4 ZNF217 SLFN14 PLXNB2 STAT1 ABCB4 DZIP3 UBXN2A C4B USP48

2.29e-03104513012EFO_0007986
Diseaseprotein-glutamine gamma-glutamyltransferase e measurement

NPTN ABCB11 RP1

2.38e-03601303EFO_0020690
Diseaselow density lipoprotein cholesterol measurement, physical activity

DDX18 ABCB11 RP1

3.12e-03661303EFO_0003940, EFO_0004611
DiseaseCholecystitis

ABCB4 ZNF761

3.14e-03191302HP_0001082
Diseasevenous thromboembolism, fibrinogen measurement

GRK5 HECTD4 SNX13

3.26e-03671303EFO_0004286, EFO_0004623
Diseasephospholipid measurement

TLCD4 ZNF600 NR2C2AP ABCB11

3.48e-031401304EFO_0004639
Diseasesusceptibility to mononucleosis measurement

ANKRD50 ADCY2 DMD

3.54e-03691303EFO_0008403
DiseaseColorectal Carcinoma

ZNF217 ZNF232 ABCB4 CDKL5 LRRC3B ADAMTS18 ABCB11 DMD PHIP

3.99e-037021309C0009402
Diseaseelectroencephalogram measurement

E2F7 PCNX2 DMD

4.31e-03741303EFO_0004357

Protein segments in the cluster

PeptideGeneStartEntry
VNNRIFQSRFQHKKT

APAF1

991

O14727
HQLIVKARFNFKQTN

ARHGEF6

161

Q15052
KNRVSIRDNQKNHVF

CD300LD

76

Q6UXZ3
RNGFKSHALQLNNRQ

C4B

1336

P0C0L5
QKLKGQENGQHRAAF

CDC14B

376

O60729
RQSKFRHVFGQAVKN

CORO1C

6

Q9ULV4
GHDSKKVNVQFLRSN

ABCB11

1141

O95342
KLRQQLQRSKQSSRH

GLCCI1

236

Q86VQ1
TRNQGRQKLARFNAH

GIT2

326

Q14161
FLIHQQSGEQKKRNG

ANKRD50

1346

Q9ULJ7
KGSTRVHALNNVNKA

DMD

66

P11532
HSQKQNRQTCVRKSL

CALN1

221

Q9BXU9
TGSKKRFENHFQTRQ

DNAJB9

131

Q9UBS3
LHNGRKKRSAQNARS

ADAMTS18

81

Q8TE60
VQRQQIRQTFKSHFG

ANXA6

396

P08133
QVRQHSRNLKLGSAF

QRICH2

1466

Q9H0J4
NIKRNHNLALGRQKG

RAD50

1066

Q92878
NKVQGTSINVFRKKH

IQCM

41

A0A1B0GVH7
FLGQNVHARKNKNVD

INPP4A

861

Q96PE3
HKNVRQQRQAASKAA

NUCKS1

86

Q9H1E3
LTHQRFQFSSLQQGK

MFSD10

296

Q14728
KLSRPFQNQTHAKRA

MAPK9

56

P45984
QQNEHRGTNLSRKEK

MAP4K3

511

Q8IVH8
FSQHVSGNRAQKLLR

MADD

796

Q8WXG6
RQKGKSHRQDAARQA

HMG20A

186

Q9NP66
KGNRNTHKDLLRFAQ

FEM1B

376

Q9UK73
QRIVNSINRHFNKAK

FSIP2

4336

Q5CZC0
TLLRVKFKSQQHRQG

PTGFR

226

P43088
HRNPSNNRQIHNGKK

PCNX2

116

A6NKB5
NNRQIHNGKKEEASR

PCNX2

121

A6NKB5
KQVNKLIHARGTNLN

PLXNB2

1106

O15031
QNGGKVRHKRQALQD

MKX

66

Q8IYA7
KLSRPFQNQTHAKRA

MAPK8

56

P45983
KSNSISQRHQNEFKN

EXPH5

1691

Q8NEV8
AKGLTQALRKAFHQN

KIAA1549L

851

Q6ZVL6
QSVHKNAFNNLKARA

LRRC3B

126

Q96PB8
HGKQKQNKRTTTFFQ

DDX18

456

Q9NVP1
VHIQKKNTKTRANFG

HECTD4

2116

Q9Y4D8
RKFQAHIRVQGEAQK

IQSEC3

736

Q9UPP2
RQISGVHKLQQTKFR

ITGB4

856

P16144
FGINKVSKLQRQIHA

DZIP3

801

Q86Y13
RLFRHSTQKNLKNSQ

ABCB4

661

P21439
TRKARIISQGNKQHL

PCDHB16

61

Q9NRJ7
NKSKQPGLARSQHNR

BRCA1

306

P38398
GQHNFQNRTLRTKSQ

ADCY2

531

Q08462
AKQKLARHGSFNTVQ

E2F7

401

Q96AV8
QERKSNFHDGRKAQQ

FNBP1

111

Q96RU3
RNSKHLKQQQYRAEN

CEP290

521

O15078
HRLKNNQSKFFRVLN

CHD3

886

Q12873
KNRAAAQRSRQKHTD

BATF2

26

Q8N1L9
RFLLGGSKQKVQQHQ

GARRE1

16

O15063
AKSLHTQKNRQFFNE

CCZ1

81

P86791
QLFKLNINRNHRGFK

CC2D1B

756

Q5T0F9
AKSLHTQKNRQFFNE

CCZ1B

81

P86790
KTVANNRDKGRANHS

MAN2C1

441

Q9NTJ4
SKNRSIQHLALGKNF

CARMIL1

506

Q5VZK9
GRSAAQKKFHVPRQN

EPS8

701

Q12929
SILAKHNGFNRQKQE

CDH8

556

P55286
RNIIKERKGRNFSQH

CYP20A1

236

Q6UW02
SNKKLRGRQHSVFQS

GPRIN3

741

Q6ZVF9
LQRLFKRQHQNNSKS

GRK5

551

P34947
HRLKNNQSKFFRVLN

CHD4

876

Q14839
TKYLKSNSRSQQNRH

CDKL5

431

O76039
VKGRKHQQAVRENTS

SCAPER

811

Q9BY12
QGAKNKNHAEQTRRA

SLC45A2

286

Q9UMX9
RNGFKSHALQLNNRQ

C4A

1336

P0C0L4
VHVNTSQRGFQQKLL

CSF2RA

96

P15509
SVLNRNTRQFGKKHL

NR2C2AP

16

Q86WQ0
ARGAQVVSKGNKQHF

PCDHB3

61

Q9Y5E6
QQKQKRHRTRFTPAQ

OTP

101

Q5XKR4
GKAFIQKSNLIRHQR

ZNF146

106

Q15072
NFHRNKLNTTQNSKV

RP1

756

P56715
QQRRLKQATQFLHKD

NRIP2

81

Q9BQI9
KKKQRRQRTHFTSQQ

PITX1

86

P78337
LSRQRDGKHQTNQTK

SNX13

421

Q9Y5W8
RNTAHQLKQKLQTVG

SLFN14

486

P0C7P3
FQRQESVRSQHKGIQ

SHB

281

Q15464
RRKKQAQANGVSHNI

SOS2

736

Q07890
HNIRKSKRNLQDNFQ

STAT1

81

P42224
HLQLKEQKNAGTRTN

STAT1

406

P42224
TKEQKNHTFPRLNRN

PLD5

426

Q8N7P1
AKKHSGRQQQQRAES

SLC47A2

501

Q86VL8
QKKAHQARAGVSQVL

POLR2B

456

P30876
HQGINFKQNDTKVLR

SIN3A

731

Q96ST3
HQAVNFKQNDTKALR

SIN3B

606

O75182
VAFRQHLQNLARTKG

SIK2

596

Q9H0K1
NSQKRRTHEAKGFIN

SHOC1

1261

Q5VXU9
NLNRQFLFQKKHVGR

UBA2

56

Q9UBT2
KNNDTQKHQGRARRK

SPATA31D4

56

Q6ZUB0
TTVGNHLQQKRSQLF

SPATA31E1

426

Q6ZUB1
GHFKNQELRQVKRQE

RANBP6

811

O60518
QAKSNTASKGRVQIH

NCAPG2

736

Q86XI2
KTRKRIFLHGNNLNS

CLVS2

221

Q5SYC1
RFLKHGQNIRDVSNK

SKA3

396

Q8IX90
SGNKLNHQKDTRQAT

FYTTD1

176

Q96QD9
GKSFSQKTNLNLHQR

ZNF567

511

Q8N184
KNNDTQKHQGRARRK

SPATA31D3

56

P0C874
GKAFNQSSQLTRHKI

ZNF107

166

Q9UII5
NRQLRHFQGRKKALQ

SENP5

51

Q96HI0
GKTFNQQLTLKRHRR

ZNF761

556

Q86XN6
GKAFTQSSKLVQHQR

ZNF383

316

Q8NA42
GRAFNQSSNLTKHKR

ZNF724

316

A8MTY0
GKTFNNTSNLRTHQR

ZNF691

121

Q5VV52
KSFNQSSNLLKHQRI

ZSCAN20

801

P17040
HLKRFQQAGFNLRKV

USP16

696

Q9Y5T5
KAFNGNSSLIRHQRI

ZNF19

196

P17023
SKKQQTNQHNYRTRS

PHIP

786

Q8WWQ0
VFKKQIDNLRTNHQG

TRAPPC6B

76

Q86SZ2
GKLFRQNSSLVDHQK

ZIK1

301

Q3SY52
TNSTNNHKDKNLRQR

NPTN

381

Q9Y639
ANGKRIVQKFNITHR

UBXN2A

181

P68543
KVFSQNSNLQRHRKI

ZNF534

486

Q76KX8
SHIRQEKAKNSLQNG

TLCD4

246

Q96MV1
HQQATLQLRKFGQRF

TMDD1

151

P0DPE3
KGFSRVSNLIQHQKT

ZNF780B

676

Q9Y6R6
GKAFNKGSNLTRHQR

ZNF829

386

Q3KNS6
KAFNQGSTLIRHQRI

ZNF582

346

Q96NG8
SQQSLKGHLRNNFQK

ZC2HC1C

41

Q53FD0
KGHLRNNFQKQLLSN

ZC2HC1C

46

Q53FD0
GKVFRQASNLLAHQR

ZNF226

621

Q9NYT6
NKQQHIFNTARKSLS

WDR62

101

O43379
RGFSQKSNLVAHQRT

ZNF133

501

P52736
GKAFNQSANLTTHKR

ZNF492

231

Q9P255
GKAFNQSANLTTHKR

ZNF253

206

O75346
NPRHKITKRGQNVTF

TRBV7-9

26

P04435
GKRFSQRKNLSQHQV

ZNF689

211

Q96CS4
NHNRNSATKNLGKIF

ZNF41

246

P51814
KSFSQNGTLIKHQRV

ZNF418

321

Q8TF45
KTFKQSSNLGQHQRI

ZNF232

311

Q9UNY5
RTHNGKSGARSKLQQ

ZNF217

176

O75362
FGERRTNKTHSNKFQ

TPTE2

351

Q6XPS3
EQRRKQFQKAENHFS

TTC16

416

Q8NEE8
GKTFRQKSNLRGHQR

ZNF782

596

Q6ZMW2
KGFNNNTKLIQHQRI

ZNF23

371

P17027
HQKQALRKSQRSQTG

ZNF674

206

Q2M3X9
KGFIQRSNFLQHQKI

ZNF623

466

O75123
KVHNFGKRSNSIKRN

PLEKHA5

151

Q9HAU0
KAFNQQSNLARHRRI

ZNF600

281

Q6ZNG1
NGGTKRQKISHQNYI

USP48

911

Q86UV5
QFIRQKRRGAFNSKQ

PTP4A1

131

Q93096
VQNKLHSANKGRKTN

TEX9

116

Q8N6V9
GKTFSQSANLAQHKR

ZNF583

246

Q96ND8
KTFSQNAGLAQHQRI

ZNF583

471

Q96ND8
GKAFKQLTQLTRHQR

ZNF850

1071

A8MQ14
KGFTQRSNLQIHQRV

ZNF214

421

Q9UL59
DIKNFGLFHRRSKQN

TRPC4

841

Q9UBN4
AKVFNQKGILAQHQR

ZNF816

571

Q0VGE8
GKAFQRSSSLVQHQR

ZFP90

316

Q8TF47
GKAFNRISSLTQHQR

ZNF554

386

Q86TJ5
QHLTFLGKANNQTLR

MYO3B

451

Q8WXR4