Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionstructural constituent of presynaptic active zone

ERC2 RIMS1 BSN

7.71e-078493GO:0098882
GeneOntologyMolecularFunctionstructural constituent of synapse

ERC2 RIMS1 BSN

1.49e-0442493GO:0098918
GeneOntologyMolecularFunctionmonoatomic cation:bicarbonate symporter activity

SLC39A4 SLC4A9

4.52e-0413492GO:0140410
GeneOntologyBiologicalProcessRNA splicing

ZC3H13 SRRM4 CCNL1 DDX42 U2AF1L4 DYRK1A PRPF38A NSRP1

2.18e-05502498GO:0008380
GeneOntologyBiologicalProcessmaintenance of presynaptic active zone structure

ERC2 BSN

8.24e-056492GO:0048790
GeneOntologyBiologicalProcessregulation of calcium-dependent activation of synaptic vesicle fusion

ERC2 RIMS1

1.15e-047492GO:0150037
GeneOntologyBiologicalProcessestablishment of skin barrier

FLG LSR FLG2

1.26e-0441493GO:0061436
GeneOntologyBiologicalProcessmRNA splicing, via spliceosome

SRRM4 DDX42 U2AF1L4 DYRK1A PRPF38A NSRP1

1.95e-04358496GO:0000398
GeneOntologyBiologicalProcessRNA splicing, via transesterification reactions with bulged adenosine as nucleophile

SRRM4 DDX42 U2AF1L4 DYRK1A PRPF38A NSRP1

1.95e-04358496GO:0000377
GeneOntologyBiologicalProcessRNA splicing, via transesterification reactions

SRRM4 DDX42 U2AF1L4 DYRK1A PRPF38A NSRP1

2.07e-04362496GO:0000375
GeneOntologyBiologicalProcessskin development

FLG LSR ASH1L EXT1 FLG2 LCE1E

2.44e-04373496GO:0043588
GeneOntologyBiologicalProcesspresynaptic active zone organization

ERC2 BSN

2.46e-0410492GO:1990709
GeneOntologyBiologicalProcesscell-cell junction organization

LSR EXT1 MARVELD2 ACE CDH11

2.88e-04246495GO:0045216
GeneOntologyBiologicalProcessmRNA processing

ZC3H13 SRRM4 DDX42 U2AF1L4 DYRK1A PRPF38A NSRP1

3.03e-04551497GO:0006397
GeneOntologyBiologicalProcessregulation of alternative mRNA splicing, via spliceosome

SRRM4 DYRK1A NSRP1

3.73e-0459493GO:0000381
GeneOntologyBiologicalProcesspositive regulation of synaptic vesicle fusion to presynaptic active zone membrane

ERC2 RIMS1

4.24e-0413492GO:0031632
GeneOntologyBiologicalProcesspositive regulation of synaptic vesicle membrane organization

ERC2 RIMS1

4.24e-0413492GO:1901634
GeneOntologyBiologicalProcesscalcium-dependent activation of synaptic vesicle fusion

ERC2 RIMS1

4.24e-0413492GO:0099502
GeneOntologyCellularComponentcytoskeleton of presynaptic active zone

ERC2 RIMS1 BSN

6.31e-078483GO:0048788
GeneOntologyCellularComponentpresynaptic cytoskeleton

ERC2 RIMS1 BSN

4.06e-0614483GO:0099569
GeneOntologyCellularComponentpresynaptic active zone cytoplasmic component

ERC2 RIMS1 BSN

1.95e-0523483GO:0098831
GeneOntologyCellularComponenttricellular tight junction

LSR MARVELD2

3.09e-054482GO:0061689
GeneOntologyCellularComponentkeratohyalin granule

FLG FLG2

5.14e-055482GO:0036457
GeneOntologyCellularComponentnuclear speck

ZC3H13 CCNL1 DDX42 U2AF1L4 DYRK1A TERT NSRP1

5.35e-05431487GO:0016607
GeneOntologyCellularComponentcell cortex region

ERC2 RIMS1 BSN

1.51e-0445483GO:0099738
GeneOntologyCellularComponentnuclear body

TCF20 ZC3H13 CCNL1 DDX42 U2AF1L4 DYRK1A TERT NSRP1

9.55e-04903488GO:0016604
HumanPhenoCervical C2/C3 vertebral fusion

ASH1L CDH11 AFF4

1.95e-0513223HP:0004602
DomainFilaggrin

FLG FLG2

6.47e-062482IPR003303
DomainZnf_FYVE_PHD

TCF20 ASH1L RIMS1 BSN

5.48e-04147484IPR011011
DomainS100_CABP

FLG FLG2

2.18e-0327482PS00303
DomainS_100

FLG FLG2

2.18e-0327482PF01023
DomainS100_Ca-bd_sub

FLG FLG2

2.34e-0328482IPR013787
DomainS100/CaBP-9k_CS

FLG FLG2

2.34e-0328482IPR001751
DomainS_100

FLG FLG2

2.34e-0328482SM01394
DomainLDLR_class-A_CS

HSPG2 MALRD1

4.74e-0340482IPR023415
DomainLdl_recept_a

HSPG2 MALRD1

5.97e-0345482PF00057
Domain-

HSPG2 MALRD1

6.23e-03464824.10.400.10
DomainZnF_C3H1

ZC3H13 U2AF1L4

6.77e-0348482SM00356
DomainLDLRA_1

HSPG2 MALRD1

6.77e-0348482PS01209
Domainzf-CCCH

ZC3H13 U2AF1L4

7.04e-0349482PF00642
DomainLDrepeatLR_classA_rpt

HSPG2 MALRD1

7.04e-0349482IPR002172
DomainLDLa

HSPG2 MALRD1

7.04e-0349482SM00192
DomainLDLRA_2

HSPG2 MALRD1

7.04e-0349482PS50068
DomainZnf_CCCH

ZC3H13 U2AF1L4

9.76e-0358482IPR000571
DomainZF_C3H1

ZC3H13 U2AF1L4

9.76e-0358482PS50103
DomainEF_Hand_1_Ca_BS

FLG CABP4 FLG2

1.03e-02175483IPR018247
DomainZINC_FINGER_C2H2_2

ZSCAN29 ZNF793 ZBTB49 CBLL2 ZNF235 REPIN1

1.39e-02775486PS50157
Pubmed

A protein interaction node at the neurotransmitter release site: domains of Aczonin/Piccolo, Bassoon, CAST, and rim converge on the N-terminal domain of Munc13-1.

ERC2 RIMS1 BSN

5.24e-08649319812333
Pubmed

Physical and functional interaction of the active zone proteins, CAST, RIM1, and Bassoon, in neurotransmitter release.

ERC2 RIMS1 BSN

5.24e-08649314734538
Pubmed

Localization of angulin-1/LSR and tricellulin at tricellular contacts of brain and retinal endothelial cells in vivo.

LSR MARVELD2

1.94e-06249224212375
Pubmed

Histone deacetylase inhibition prevents cell death induced by loss of tricellular tight junction proteins in temperature-sensitive mouse cochlear cells.

LSR MARVELD2

1.94e-06249228767685
Pubmed

LSR defines cell corners for tricellular tight junction formation in epithelial cells.

LSR MARVELD2

1.94e-06249221245199
Pubmed

Deletion of the presynaptic scaffold CAST reduces active zone size in rod photoreceptors and impairs visual processing.

ERC2 BSN

1.94e-06249222933801
Pubmed

Development of nano affinity columns for the study of ligand (including SARS-CoV-2 related proteins) binding to heparan sulfate proteoglycans.

HSPG2 TERT

1.94e-06249234132262
Pubmed

Expression of filaggrin-2 protein in the epidermis of human skin diseases: a comparative analysis with filaggrin.

FLG FLG2

1.94e-06249224813994
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

ZSCAN29 FLG TCF20 DROSHA ZC3H13 DDX42 PRPF38A FLG2 NSRP1 AFF4

2.22e-061082491038697112
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

TEX2 ZC3H13 CCNL1 DDX42 ASH1L DYRK1A PRPF38A TNFAIP3 REPIN1 AFF4

2.26e-061084491011544199
Pubmed

The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.

LSR TCF20 CCNL1 DDX42 DYRK1A ERC2 CHD1 REPIN1 NSRP1 USP6NL

5.68e-061203491029180619
Pubmed

Histone methyltransferase Ash1l suppresses interleukin-6 production and inflammatory autoimmune diseases by inducing the ubiquitin-editing enzyme A20.

ASH1L TNFAIP3

5.83e-06349224012418
Pubmed

Defects of filaggrin-like proteins in both lesional and nonlesional atopic skin.

FLG FLG2

5.83e-06349223403047
Pubmed

GATA3 regulates FLG and FLG2 expression in human primary keratinocytes.

FLG FLG2

5.83e-06349228928464
Pubmed

Molecular dissection of the photoreceptor ribbon synapse: physical interaction of Bassoon and RIBEYE is essential for the assembly of the ribbon complex.

ERC2 BSN

5.83e-06349215728193
Pubmed

Cast: a novel protein of the cytomatrix at the active zone of synapses that forms a ternary complex with RIM1 and munc13-1.

ERC2 RIMS1

5.83e-06349212163476
Pubmed

Filaggrin and filaggrin 2 processing are linked together through skin aspartic acid protease activation.

FLG FLG2

5.83e-06349232437351
Pubmed

The synaptic vesicle cycle.

ERC2 RIMS1 BSN

1.15e-053149315217342
Pubmed

A family of RIM-binding proteins regulated by alternative splicing: Implications for the genesis of synaptic active zones.

ERC2 RIMS1

1.16e-05449212391317
Pubmed

Fusion Competent Synaptic Vesicles Persist upon Active Zone Disruption and Loss of Vesicle Docking.

ERC2 RIMS1

1.16e-05449227537483
Pubmed

Loss of corneal epithelial heparan sulfate leads to corneal degeneration and impaired wound healing.

HSPG2 EXT1

1.16e-05449226024086
Pubmed

Analysis of the 'angulin' proteins LSR, ILDR1 and ILDR2--tricellulin recruitment, epithelial barrier function and implication in deafness pathogenesis.

LSR MARVELD2

1.94e-05549223239027
Pubmed

ELKS1 Captures Rab6-Marked Vesicular Cargo in Presynaptic Nerve Terminals.

ERC2 RIMS1

1.94e-05549232521280
Pubmed

Expression of Cornified Envelope Proteins in Skin and Its Relationship with Atopic Dermatitis Phenotype.

FLG FLG2

2.91e-05649227304082
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

LSR DROSHA MRM1 CCNL1 DYRK1A CHD1 PRPF38A REPIN1 USP6NL AFF4

3.75e-051497491031527615
Pubmed

A repressor complex, AP4 transcription factor and geminin, negatively regulates expression of target genes in nonneuronal cells.

DYRK1A REPIN1

4.07e-05749216924111
Pubmed

Dopamine Secretion Is Mediated by Sparse Active Zone-like Release Sites.

ERC2 RIMS1

4.07e-05749229398114
Pubmed

Rebuilding essential active zone functions within a synapse.

ERC2 RIMS1

4.07e-05749235176221
Pubmed

Munc13 supports fusogenicity of non-docked vesicles at synapses with disrupted active zones.

ERC2 RIMS1

4.07e-05749236398873
Pubmed

JNK1/2-dependent phosphorylation of angulin-1/LSR is required for the exclusive localization of angulin-1/LSR and tricellulin at tricellular contacts in EpH4 epithelial sheet.

LSR MARVELD2

5.42e-05849224889144
Pubmed

Human ISG15 conjugation targets both IFN-induced and constitutively expressed proteins functioning in diverse cellular pathways.

CCNL1 DDX42 DYRK1A CHD1

6.38e-0515249416009940
Pubmed

Characterization of cyclin L2, a novel cyclin with an arginine/serine-rich domain: phosphorylation by DYRK1A and colocalization with splicing factors.

CCNL1 DYRK1A

6.96e-05949214623875
Pubmed

Superresolution imaging of chemical synapses in the brain.

RIMS1 BSN

6.96e-05949221144999
Pubmed

The protein kinase DYRK1A regulates caspase-9-mediated apoptosis during retina development.

DYRK1A BSN

1.50e-041349219081073
Pubmed

Calcium channels link the muscle-derived synapse organizer laminin β2 to Bassoon and CAST/Erc2 to organize presynaptic active zones.

ERC2 BSN

1.75e-041449221228161
Pubmed

FBW7 suppresses ovarian cancer development by targeting the N6-methyladenosine binding protein YTHDF2.

FLG HSPG2 DYRK1A CHD1 REPIN1 NSRP1

1.93e-0460149633658012
Pubmed

No replication of genetic association between candidate polymorphisms and Alzheimer's disease.

HSPG2 ACE

2.30e-041649219889475
Pubmed

Single nucleotide polymorphisms of microRNA machinery genes modify the risk of renal cell carcinoma.

DROSHA NSRP1

2.93e-041849219047128
Pubmed

Analyses of associations with asthma in four asthma population samples from Canada and Australia.

FLG ACE MUC7

3.02e-049249319247692
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

TCF20 ZC3H13 DDX42 U2AF1L4 CHD1 NSRP1 AFF4

3.60e-0495449736373674
Pubmed

mSYD1A, a mammalian synapse-defective-1 protein, regulates synaptogenic signaling and vesicle docking.

ERC2 BSN

3.64e-042049223791195
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

TCF20 DYRK1A ERC2 RIMS1 BSN CDH11 AFF4

3.80e-0496349728671696
Pubmed

Variation in genes of the epidermal differentiation complex in German atopic dermatitis patients.

FLG FLG2

4.01e-042149219601998
Pubmed

A germline-specific class of small RNAs binds mammalian Piwi proteins.

DDX42 ASH1L BSN REPIN1 AFF4

4.23e-0445049516751776
Pubmed

Rap1 controls epiblast morphogenesis in sync with the pluripotency states transition.

LSR MARVELD2

4.83e-042349235998584
Pubmed

Redundant functions of RIM1alpha and RIM2alpha in Ca(2+)-triggered neurotransmitter release.

ERC2 RIMS1

6.18e-042649217124501
Pubmed

In Vitro Identification of Histatin 5 Salivary Complexes.

FLG MUC7

6.67e-042749226544073
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

TCF20 KANSL1 ZC3H13 CCNL1 RIMS1 PRPF38A

7.38e-0477449615302935
Pubmed

Overlapping Activities of Two Neuronal Splicing Factors Switch the GABA Effect from Excitatory to Inhibitory by Regulating REST.

SRRM4 ERC2 RIMS1

7.93e-0412849330995482
Pubmed

Profiling of tyrosine phosphorylation pathways in human cells using mass spectrometry.

DYRK1A CHD1

8.25e-043049212522270
Pubmed

Mechanisms and Consequences of Dopamine Depletion-Induced Attenuation of the Spinophilin/Neurofilament Medium Interaction.

HSPG2 ERC2 BSN

8.48e-0413149328634551
Pubmed

Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.

LSR TCF20 ZC3H13 ASH1L ZNF235 TERT

9.22e-0480849620412781
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

LSR TEX2 ZC3H13 DDX42 CHD1 MARVELD2 NSRP1 USP6NL

1.04e-03148749833957083
Pubmed

Chondrocytes respond to an altered heparan sulfate composition with distinct changes of heparan sulfate structure and increased levels of chondroitin sulfate.

HSPG2 EXT1

1.25e-033749232201365
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

LSR TCF20 TEX2 DYRK1A TNFAIP3 USP6NL

1.28e-0386149636931259
Pubmed

Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.

TCF20 DDX42 CHD1 AFF4

1.36e-0334149432971831
InteractionFAM76A interactions

CCNL1 DDX42 PRPF38A NSRP1

1.65e-0721484int:FAM76A
InteractionDHX8 interactions

TCF20 KANSL1 ZC3H13 DDX42 CHD1 PRPF38A NSRP1 AFF4

4.03e-07292488int:DHX8
InteractionPRPF38A interactions

SRRM4 CCNL1 DDX42 PRPF38A NSRP1

3.97e-05161485int:PRPF38A
InteractionBSN interactions

ERC2 RIMS1 BSN

7.87e-0535483int:BSN
InteractionC1orf35 interactions

FLG SRRM4 CCNL1 DDX42 PRPF38A NSRP1

8.08e-05304486int:C1orf35
InteractionGAGE2E interactions

ZC3H13 PRPF38A NSRP1

8.57e-0536483int:GAGE2E
InteractionRIMS1 interactions

ERC2 RIMS1 BSN

1.18e-0440483int:RIMS1
InteractionERC2 interactions

ERC2 RIMS1 BSN

1.36e-0442483int:ERC2
Cytoband17q23.3

TEX2 DDX42 ACE

4.55e-063049317q23.3
Cytoband19q13.12

ZNF793 LSR U2AF1L4

6.47e-057249319q13.12
Cytoband1q21.3

FLG FLG2 LCE1E

2.73e-041174931q21.3
CytobandEnsembl 112 genes in cytogenetic band chr17q23

TEX2 DDX42 ACE

2.94e-04120493chr17q23
Cytoband16q21

BEAN1 CDH11

1.07e-034549216q21
CytobandEnsembl 112 genes in cytogenetic band chr16q21

BEAN1 CDH11

3.26e-0379492chr16q21
Cytoband5q31

SLC4A9 AFF4

6.77e-031154925q31
GeneFamilyEF-hand domain containing|S100 fused type protein family

FLG FLG2

6.34e-0573221350
GeneFamilyEF-hand domain containing

FLG CABP4 FLG2

6.71e-03219323863
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZSCAN29 ZNF793 ZBTB49 ZNF235 REPIN1

8.05e-0371832528
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

KANSL1 CCNL1 ASH1L DYRK1A CHD1 TNFAIP3

5.92e-08188496ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

KANSL1 CCNL1 ASH1L CHD1 TNFAIP3 AFF4

8.54e-0820049612f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

KANSL1 CCNL1 ASH1L CHD1 TNFAIP3

2.20e-0619249547646d7e4990be85072987f92bf18d52f8da752e
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HSPG2 LSR BEAN1 ANO8

2.54e-051554948e239470799426ea474a36f57e1b7e0d9365ca5f
ToppCell10x5'-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8|bone_marrow / Manually curated celltypes from each tissue

KANSL1 CCNL1 CHD1 TNFAIP3

2.61e-051564941545169694f686d28648a68b552c2ae606599d66
ToppCellFetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SRRM4 ERC2 RIMS1 BSN

2.81e-051594947747cef94c55144fddcd024a7495318357f1351b
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

KANSL1 CCNL1 CHD1 TNFAIP3

3.73e-051714942e9a20f8980b78325c52065a9c14ab3656267c05
ToppCelldroplet-Thymus-nan-21m-Lymphocytic-B_cell|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZSCAN29 AGMO MARVELD2 ZNF235

3.91e-051734940a0cd40bb5f61431fe34758626c8a63ec610a8a5
ToppCell10x5'-Liver-Lymphocytic_T_CD4-T_CD4/CD8|Liver / Manually curated celltypes from each tissue

KANSL1 CCNL1 ASH1L TNFAIP3

4.66e-05181494f2315414e714ac86211546a935660c4be6e85f1b
ToppCelldroplet-Spleen-nan-18m|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCNL1 ASH1L CHD1 AFF4

4.76e-05182494eeb5dfa4539e9ca5220f26bc2b65717ddcf13b6c
ToppCelldroplet-Spleen-nan-18m-Lymphocytic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCNL1 ASH1L CHD1 AFF4

4.86e-0518349428cbf909424f3be4491d49832f0aca0386560814
ToppCellCalu_3-infected|Calu_3 / Cell line, Condition and Strain

CCNL1 ASH1L TNFAIP3 AFF4

4.86e-051834948f7f5000645f24f20a8d7700c4df1f8953a1780b
ToppCelldroplet-Spleen-nan-18m-Lymphocytic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCNL1 ASH1L CHD1 AFF4

4.86e-051834943fa608aa6b119869ec3280dc388dfee57160e63a
ToppCellFetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SRRM4 ERC2 RIMS1 BSN

5.18e-05186494b45cce768e4bf91da194fd9660cab7520dfb15ac
ToppCellEntopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Entopeduncular / BrainAtlas - Mouse McCarroll V32

BEAN1 SRRM4 ERC2 BSN

5.74e-051914945d24022cec293bc8d9e978ae99a109e660bb8f83
ToppCellEntopeduncular-Neuronal-Inhibitory|Entopeduncular / BrainAtlas - Mouse McCarroll V32

BEAN1 SRRM4 ERC2 BSN

5.74e-0519149473dae4cdea86aec62393ad7303dc7375a6b3fc86
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature4_(1)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

CCNL1 CHD1 TNFAIP3 AFF4

5.98e-05193494dbf0fe496254320c894568c31e5f9ce63707d1b5
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_immature|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

HSPG2 LSR MARVELD2 ACE

6.47e-0519749462c0a90869431e582bb7bb329e0b0cc59123d3d1
ToppCellCOVID-19_Mild|World / Disease group, lineage and cell class

KANSL1 CCNL1 CHD1 TNFAIP3

6.47e-051974945c33454b10023decd2f5ccda9229b6512659711e
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_immature-Tip-like|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

HSPG2 LSR MARVELD2 ACE

6.47e-0519749416f0eb047df9d702518f82ee99c6e7dc1350b2fb
ToppCellPBMC-Mild|PBMC / Location, Disease Group, Cell group, Cell class (2021.03.09)

KANSL1 CCNL1 CHD1 TNFAIP3

6.60e-0519849444417089b62056269cac38d3134ff209c05b7007
ToppCellPBMC-Mild|PBMC / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

KANSL1 CCNL1 CHD1 TNFAIP3

6.60e-0519849428ef3fc4c17dcb765537b75917f7db78baa522db
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_capilar-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

HSPG2 LSR MARVELD2 ACE

6.73e-05199494236b1417ed0875e98c6ec1ec714003bfce438d65
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_capilar-A|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

HSPG2 LSR MARVELD2 ACE

6.73e-05199494c5c12c8288fe868322bae9d691b91fee953ceb3e
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_immature-Tip-like-G|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

HSPG2 LSR HRC ACE

6.73e-051994941295f34a350bf48987e2fad411aaac3630efd3f1
ToppCellCOVID-19|World / Disease, condition lineage and cell class

CCNL1 CHD1 TNFAIP3 AFF4

6.86e-052004947dec470c379cd89f05a0f37c8628b21f136e52f0
ToppCellCOVID-19-COVID-19_Mild|COVID-19 / Disease, condition lineage and cell class

KANSL1 CCNL1 CHD1 TNFAIP3

6.86e-0520049462c25042086f1afd1102e0720e933c2e476468fd
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

HSPG2 LSR MARVELD2 ACE

6.86e-05200494061ba851f941c616ddb462512e826c412881c3ce
Diseaseautism spectrum disorder (implicated_via_orthology)

TCF20 ASH1L DYRK1A CHD1 EXT1 RIMS1

1.17e-07152456DOID:0060041 (implicated_via_orthology)
DiseaseLung diseases

ACE TERT AFF4

2.33e-0478453C0024115
DiseaseAlzheimer disease, polygenic risk score

TCF20 KANSL1 ERC2 RIMS1 ACE SLC4A9

2.52e-04586456EFO_0030082, MONDO_0004975
DiseaseFebrile seizure (within the age range of 3 months to 6 years)

ERC2 BSN

3.43e-0418452HP_0002373
DiseaseNeurodevelopmental Disorders

ASH1L DYRK1A RIMS1

3.91e-0493453C1535926
Diseasemyelodysplastic syndrome (is_marker_for)

DDX42 TERT

4.25e-0420452DOID:0050908 (is_marker_for)
Diseasechronic myeloid leukemia (is_marker_for)

ACE TERT

7.79e-0427452DOID:8552 (is_marker_for)
DiseaseVertigo

MALRD1 DROSHA RIMS1

1.26e-03139453HP_0002321
Diseaserespiratory system disease

FLG SLC9A4 TNFAIP3

1.42e-03145453EFO_0000684
DiseaseParkinson disease

KANSL1 ASH1L DYRK1A RIMS1

1.44e-03321454MONDO_0005180

Protein segments in the cluster

PeptideGeneStartEntry
ERSHHSPSERSHHSP

C2orf16

1731

Q68DN1
SHHSPSERRHHSPSE

C2orf16

1741

Q68DN1
LTSAEDRHRHGPHAH

SLC4A9

361

Q96Q91
HYFRPHETHHSPSRR

ASH1L

2721

Q9NR48
HQSHHHSEARNHGRA

CATSPER1

76

Q8NEC5
FSIRHRSLHRHSHGP

ACE

1281

P12821
NTPSHHRVHHGRNRY

AGMO

216

Q6ZNB7
EQSRDGSRHPRSHHE

FLG

651

P20930
GSRHPRSHHEDRAGH

FLG

656

P20930
EQSRHGSRHPRSHHE

FLG

976

P20930
GSRHPRSHHEDRAGH

FLG

981

P20930
RNPRSHQEDRASHGH

FLG

1631

P20930
RDGSRHPRSHHEDRA

FLG

2276

P20930
HPRSHHEDRAGHGHS

FLG

2281

P20930
GSRHPRSHQEDRAGH

FLG

2926

P20930
QSRHGSRHPRSHHED

FLG

3246

P20930
SRHPRSHHEDRAGHG

FLG

3251

P20930
SRDGSRHPTSHHEDR

FLG

3571

P20930
RHPTSHHEDRAGHGH

FLG

3576

P20930
RARSDPTHQHRHSGG

DYRK1A

526

Q13627
RSHSESPRRHHNHGS

CCNL1

431

Q9UK58
PPSTLHGRSHHSHQR

CBLL2

406

Q8N7E2
RSHSDHRSHSDHRLH

CHD1

1626

O14646
HRSHSDHRLHSDHRS

CHD1

1631

O14646
RSHGNDHHSKEHQRS

AFF4

196

Q9UHB7
QRHAEHHARREHDSG

ANO8

911

Q9HCE9
RDSHRHREASHRDSH

NSRP1

341

Q9H0G5
PSRHQTHGSHLRLHQ

HSPG2

2671

P98160
PERPRHHHHDSDSNS

MMTAG2

221

Q9BU76
DSEVHSGGSHRPHSR

FLG2

1581

Q5D862
PGRHASAKEHRHGDH

BSN

3636

Q9UPA5
HPESSSRHTDGHRHG

DDX42

846

Q86XP3
LSHHQTRPDRTHRQH

KANSL1

736

Q7Z3B3
HHRSPGRSQHSNHRP

ERC2

931

O15083
RSRLEAPAHAHSHPH

PRR7

81

Q8TB68
TRHHDASRSPVDHRT

RIMS1

991

Q86UR5
HHGEENHRPSVDHTQ

MALRD1

1126

Q5VYJ5
DHELRHRRHHHQSPK

MUC7

26

Q8TAX7
RREEHSGRNGLHHPS

EXT1

36

Q16394
SHRHRPDSLHDAAQR

CABP4

96

P57796
ERRGHLRPSFHGHHE

CDH11

26

P55287
SRLPHHSESRQEHER

MARVELD2

491

Q8N4S9
RHHRSHRHRPQSSDC

LCE1E

81

Q5T753
HHHHRRRRHREYEHG

BEAN1

81

Q3B7T3
SHHHRTRDPRDNGSR

LSR

566

Q86X29
HRHRDHSHGRGERHR

DROSHA

231

Q9NRR4
VTRHFSHAARHGERP

MRM1

16

Q6IN84
EAHSDHSHRHRGASS

SLC39A4

236

Q6P5W5
HGHGRDHHRSHSPLL

SLC9A4

781

Q6AI14
DGHHHRDPSHRHRSH

HRC

286

P23327
SQGSHLAAHRRDHAP

REPIN1

441

Q9BWE0
GRRESGAPHRRHEHS

USP6NL

401

Q92738
SHRTEHQRTHTGERP

ZNF793

296

Q6ZN11
ARQLHASHAPDHTRH

TNFAIP3

501

P21580
HRHRHHRCPSRSQSS

SRRM4

181

A7MD48
RSRSKSPGHHRSHRH

PRPF38A

276

Q8NAV1
SPGHHRSHRHRSHSK

PRPF38A

281

Q8NAV1
HHHPDRRYSRSTQEH

TCF20

761

Q9UGU0
GHHPRERNHRCSPDH

U2AF1L4

201

Q8WU68
DESHPHASPSVNRHH

ZBTB49

171

Q6ZSB9
HFSAHRRIHTGERPH

ZSCAN29

776

Q8IWY8
HSRHNSPSGHLTHSR

TEX2

731

Q8IWB9
SHFHTHQRVHTGERP

ZNF235

696

Q14590
GTRHSHPSVGRQHHA

TERT

291

O14746
HDHERTSQSHDRRHE

ZC3H13

401

Q5T200