Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionRNA polymerase II cis-regulatory region sequence-specific DNA binding

HOXA13 JUN HOXB3 HOXB6 OTX1 NKX2-3 DMRTA1 POU5F1 DLX5 RUNX3 FOXI3 IRX2 CREB3L2 CRX

3.75e-0512446514GO:0000978
GeneOntologyMolecularFunctioncis-regulatory region sequence-specific DNA binding

HOXA13 JUN HOXB3 HOXB6 OTX1 NKX2-3 DMRTA1 POU5F1 DLX5 RUNX3 FOXI3 IRX2 CREB3L2 CRX

4.75e-0512716514GO:0000987
GeneOntologyMolecularFunctionHMG box domain binding

JUN POU5F1 DLX5

5.57e-0523653GO:0071837
GeneOntologyMolecularFunctionDNA-binding transcription factor activity, RNA polymerase II-specific

HOXA13 JUN HOXB3 HOXB6 OTX1 NKX2-3 DMRTA1 POU5F1 DLX5 RUNX3 FOXI3 IRX2 CREB3L2 CRX

1.47e-0414126514GO:0000981
GeneOntologyMolecularFunctionRNA polymerase II transcription regulatory region sequence-specific DNA binding

HOXA13 JUN HOXB3 HOXB6 OTX1 NKX2-3 DMRTA1 POU5F1 DLX5 RUNX3 FOXI3 IRX2 CREB3L2 CRX

2.07e-0414596514GO:0000977
GeneOntologyMolecularFunctionDNA-binding transcription activator activity, RNA polymerase II-specific

HOXA13 JUN HOXB3 OTX1 POU5F1 DLX5 CREB3L2 CRX

4.51e-04560658GO:0001228
GeneOntologyMolecularFunctioncobalamin binding

TCN2 CUBN

4.62e-0410652GO:0031419
GeneOntologyMolecularFunctionDNA-binding transcription activator activity

HOXA13 JUN HOXB3 OTX1 POU5F1 DLX5 CREB3L2 CRX

4.83e-04566658GO:0001216
GeneOntologyMolecularFunctionchromatin binding

TRIM66 JUN ARID1B TRIM28 KAT6A LEMD2 POU5F1 NUP153 CRX

6.20e-04739659GO:0003682
GeneOntologyMolecularFunctioncAMP response element binding

JUN CREB3L2

6.74e-0412652GO:0035497
GeneOntologyMolecularFunctionprotein-macromolecule adaptor activity

YTHDF1 ARID1B TRIM28 KAT6A DVL2 TAF15 NCSTN PARP14 CAPRIN1 NUP153 FAN1

1.20e-0311606511GO:0030674
GeneOntologyMolecularFunctionmolecular adaptor activity

YTHDF1 ARID1B TRIM28 KAT6A EIF4G1 DVL2 TAF15 NCSTN PARP14 CAPRIN1 NUP153 FAN1

1.28e-0313566512GO:0060090
GeneOntologyBiologicalProcessanimal organ morphogenesis

HOXA13 JUN HOXB3 HOXB6 OTX1 ACAN KAT6A LEMD2 LAMA1 DVL1 DVL2 NKX2-3 MUC19 DLX5 FOXI3 ITGAV IRX2 WNK4 CRX

7.00e-0912696519GO:0009887
GeneOntologyBiologicalProcessembryo development

HOXA13 HOXB3 HOXB6 OTX1 SEC24C TRIM28 KAT6A LAMA1 DVL1 DVL2 CLASP2 POU5F1 DLX5 CUBN FOXI3 ITGAV IRX2

1.47e-0614376517GO:0009790
GeneOntologyBiologicalProcessembryonic morphogenesis

HOXA13 HOXB3 HOXB6 OTX1 TRIM28 DVL1 DVL2 CLASP2 POU5F1 DLX5 ITGAV IRX2

1.99e-067136512GO:0048598
GeneOntologyBiologicalProcessmorphogenesis of an epithelial sheet

LAMA1 DVL1 DVL2 CLASP2 ITGAV

3.62e-0674655GO:0002011
GeneOntologyBiologicalProcesstissue morphogenesis

HOXA13 TRIM28 LAMA1 DVL1 DVL2 CLASP2 POU5F1 RUNX3 ITGAV IRX2 WNK4

2.04e-057506511GO:0048729
GeneOntologyBiologicalProcessmorphogenesis of an epithelium

HOXA13 TRIM28 LAMA1 DVL1 DVL2 CLASP2 RUNX3 ITGAV IRX2 WNK4

2.23e-056196510GO:0002009
GeneOntologyBiologicalProcessconvergent extension

TRIM28 DVL1 DVL2

2.79e-0519653GO:0060026
GeneOntologyBiologicalProcessepithelium development

HOXA13 FLNB JUN SIDT2 TRIM28 LAMA1 DVL1 DVL2 CLASP2 DLX5 RUNX3 FOXI3 ITGAV IRX2 WNK4

3.99e-0514696515GO:0060429
GeneOntologyBiologicalProcessneural plate elongation

DVL1 DVL2

5.84e-054652GO:0014022
GeneOntologyBiologicalProcessconvergent extension involved in neural plate elongation

DVL1 DVL2

5.84e-054652GO:0022007
GeneOntologyBiologicalProcessembryonic organ development

HOXB3 HOXB6 OTX1 TRIM28 KAT6A DVL1 DVL2 DLX5 ITGAV

6.29e-05561659GO:0048568
GeneOntologyBiologicalProcessstress granule assembly

YTHDF1 UBAP2L CAPRIN1

1.98e-0436653GO:0034063
GeneOntologyBiologicalProcessconvergent extension involved in organogenesis

DVL1 DVL2

2.03e-047652GO:0060029
GeneOntologyBiologicalProcesspositive regulation of stress granule assembly

UBAP2L CAPRIN1

2.70e-048652GO:0062029
GeneOntologyBiologicalProcesspositive regulation of neuron projection arborization

DVL1 DVL2

2.70e-048652GO:0150012
GeneOntologyBiologicalProcesscell morphogenesis

YTHDF1 HOXA13 FLNB SIDT2 LAMA1 DVL1 DVL2 CLASP2 DLX5 RUNX3 CAPRIN1 ARHGAP33

3.11e-0411946512GO:0000902
GeneOntologyBiologicalProcessneural plate morphogenesis

DVL1 DVL2

3.47e-049652GO:0001839
GeneOntologyBiologicalProcesstube development

HOXA13 JUN HIKESHI KAT6A LAMA1 EIF4G1 DVL1 DVL2 NKX2-3 MUC19 ITGAV IRX2 WNK4

3.69e-0414026513GO:0035295
GeneOntologyBiologicalProcesscobalamin transport

TCN2 CUBN

4.33e-0410652GO:0015889
GeneOntologyBiologicalProcesschordate embryonic development

HOXB3 HOXB6 SEC24C TRIM28 DVL1 DVL2 POU5F1 CUBN FOXI3 ITGAV

5.07e-049066510GO:0043009
GeneOntologyBiologicalProcessregulation of basement membrane organization

LAMA1 CLASP2

5.28e-0411652GO:0110011
GeneOntologyBiologicalProcessconvergent extension involved in gastrulation

DVL1 DVL2

5.28e-0411652GO:0060027
GeneOntologyBiologicalProcessgastrulation

DVL1 DVL2 CLASP2 POU5F1 ITGAV

5.48e-04212655GO:0007369
GeneOntologyBiologicalProcessneuron projection development

YTHDF1 JUN ARID1B LAMA1 DVL1 DVL2 CLASP2 DLX5 RUNX3 CAPRIN1 ARHGAP33 CREB3L2

6.03e-0412856512GO:0031175
GeneOntologyBiologicalProcessembryo development ending in birth or egg hatching

HOXB3 HOXB6 SEC24C TRIM28 DVL1 DVL2 POU5F1 CUBN FOXI3 ITGAV

6.17e-049296510GO:0009792
GeneOntologyBiologicalProcessregulation of stress granule assembly

UBAP2L CAPRIN1

6.32e-0412652GO:0062028
GeneOntologyBiologicalProcessskeletal system development

HOXA13 HOXB3 HOXB6 ACAN DLX5 RUNX3 RAI1 CREB3L2

6.75e-04615658GO:0001501
GeneOntologyBiologicalProcessinner ear morphogenesis

OTX1 DVL1 DVL2 DLX5

7.36e-04129654GO:0042472
GeneOntologyCellularComponentchromatin

HOXA13 TRIM66 JUN HOXB3 HOXB6 ARID1B OTX1 TRIM28 KAT6A LEMD2 NKX2-3 DMRTA1 POU5F1 DLX5 RUNX3 IRX2 CREB3L2 CRX

3.64e-0714806518GO:0000785
GeneOntologyCellularComponentcytoplasmic stress granule

YTHDF1 UBAP2L EIF4G1 CAPRIN1

2.28e-0496654GO:0010494
MousePhenoneonatal lethality

FLNB JUN HOXB3 OTX1 HIKESHI ACAN KAT6A RANBP9 DLX5 RUNX3 FOXI3 ITGAV CAPRIN1 CREB3L2

5.25e-067996014MP:0002058
MousePhenoperinatal lethality

FLNB JUN HOXB3 ARID1B OTX1 HIKESHI ACAN KAT6A DVL2 RANBP9 DLX5 RUNX3 FOXI3 ITGAV CAPRIN1 CREB3L2

1.48e-0511306016MP:0002081
MousePhenoneonatal lethality, complete penetrance

JUN OTX1 HIKESHI ACAN KAT6A DLX5 FOXI3 ITGAV CAPRIN1 CREB3L2

8.20e-055346010MP:0011087
MousePhenoabnormal pharyngeal arch morphology

KAT6A LEMD2 DLX5 NCSTN FOXI3 ITGAV

8.89e-05171606MP:0002884
MousePhenoabnormal thoracic vertebrae morphology

FLNB HOXB6 KAT6A DVL2 RAI1

9.35e-05107605MP:0003047
MousePhenoprotruding tongue

ACAN TMEM209 CREB3L2

1.09e-0422603MP:0009908
MousePhenoabnormal craniofacial morphology

FLNB JUN OTX1 ACAN KAT6A LEMD2 TMEM209 NKX2-3 DLX5 NCSTN RUNX3 FOXI3 ITGAV HNRNPH2 RAI1 CREB3L2

1.56e-0413726016MP:0000428
MousePhenocraniofacial phenotype

FLNB JUN OTX1 ACAN KAT6A LEMD2 TMEM209 NKX2-3 DLX5 NCSTN RUNX3 FOXI3 ITGAV HNRNPH2 RAI1 CREB3L2

1.56e-0413726016MP:0005382
MousePhenoabnormal cervical vertebrae morphology

FLNB HOXB3 HOXB6 KAT6A RAI1

1.61e-04120605MP:0003048
MousePhenodistended abdomen

OTX1 ACAN DLX5 CREB3L2

1.71e-0465604MP:0001270
MousePhenoabnormal intervertebral disk morphology

FLNB ACAN DLX5 RAI1

1.92e-0467604MP:0004173
MousePhenoperinatal lethality, complete penetrance

JUN ARID1B OTX1 HIKESHI ACAN KAT6A DLX5 FOXI3 ITGAV CAPRIN1 CREB3L2

1.93e-047126011MP:0011089
MousePhenoabnormal symphysis morphology

FLNB ACAN DLX5 RAI1

2.40e-0471604MP:0030877
MousePhenoabnormal tongue position

ACAN TMEM209 CREB3L2

3.10e-0431603MP:0031443
MousePhenoabnormal phalanx morphology

HOXA13 FLNB DLX5 RAI1

3.12e-0476604MP:0005306
MousePhenobrachydactyly

HOXA13 ACAN DLX5

3.74e-0433603MP:0002544
MousePhenoectrodactyly

HOXA13 DLX5

3.75e-047602MP:0005230
MousePhenoabnormal presacral vertebrae morphology

FLNB HOXB3 HOXB6 KAT6A DVL2 RAI1

3.94e-04225606MP:0000459
DomainHomeobox_CS

HOXA13 HOXB3 HOXB6 OTX1 NKX2-3 POU5F1 DLX5 IRX2 CRX

1.57e-08186659IPR017970
DomainHomeobox

HOXA13 HOXB3 HOXB6 OTX1 NKX2-3 POU5F1 DLX5 IRX2 CRX

1.13e-07234659PF00046
DomainHOMEOBOX_1

HOXA13 HOXB3 HOXB6 OTX1 NKX2-3 POU5F1 DLX5 IRX2 CRX

1.22e-07236659PS00027
DomainHOX

HOXA13 HOXB3 HOXB6 OTX1 NKX2-3 POU5F1 DLX5 IRX2 CRX

1.26e-07237659SM00389
DomainHOMEOBOX_2

HOXA13 HOXB3 HOXB6 OTX1 NKX2-3 POU5F1 DLX5 IRX2 CRX

1.36e-07239659PS50071
DomainHomeobox_dom

HOXA13 HOXB3 HOXB6 OTX1 NKX2-3 POU5F1 DLX5 IRX2 CRX

1.36e-07239659IPR001356
DomainDishevelled_fam

DVL1P1 DVL1 DVL2

1.61e-074653IPR008339
DomainDishevelled

DVL1P1 DVL1 DVL2

1.61e-074653PF02377
DomainDishevelled_protein_dom

DVL1P1 DVL1 DVL2

1.61e-074653IPR003351
Domain-

HOXA13 HOXB3 HOXB6 OTX1 NKX2-3 POU5F1 DLX5 IRX2 CRX

5.64e-072836591.10.10.60
DomainDIX

DVL1P1 DVL1 DVL2

1.39e-067653PF00778
DomainDIX

DVL1P1 DVL1 DVL2

1.39e-067653IPR001158
DomainDIX

DVL1P1 DVL1 DVL2

1.39e-067653PS50841
DomainDAX

DVL1P1 DVL1 DVL2

1.39e-067653SM00021
DomainHomeodomain-like

HOXA13 HOXB3 HOXB6 OTX1 NKX2-3 POU5F1 DLX5 IRX2 CRX

2.12e-06332659IPR009057
DomainDVL-1

DVL1P1 DVL1

1.19e-052652IPR008340
DomainOtx_TF_C

OTX1 CRX

3.57e-053652IPR013851
Domainzf-RNPHF

HNRNPH1 HNRNPH2

3.57e-053652PF08080
DomainZnf_CHHC

HNRNPH1 HNRNPH2

3.57e-053652IPR012996
DomainDsh_C

DVL1 DVL2

3.57e-053652PF12316
DomainTF_Otx

OTX1 CRX

3.57e-053652PF03529
DomainDishevelled_C-dom

DVL1 DVL2

3.57e-053652IPR024580
DomainDEP

DVL1P1 DVL1 DVL2

5.91e-0522653PF00610
DomainDEP

DVL1P1 DVL1 DVL2

5.91e-0522653PS50186
DomainDEP

DVL1P1 DVL1 DVL2

5.91e-0522653SM00049
DomainDEP_dom

DVL1P1 DVL1 DVL2

6.78e-0523653IPR000591
DomainDsh/Dvl-rel

DVL1 DVL2

7.12e-054652IPR015506
DomainPHD

TRIM66 TRIM28 KAT6A RAI1

2.61e-0489654SM00249
DomainHomeobox_metazoa

HOXB3 HOXB6 NKX2-3 DLX5

2.73e-0490654IPR020479
DomainZnf_PHD

TRIM66 TRIM28 KAT6A RAI1

2.85e-0491654IPR001965
DomainZF_PHD_2

TRIM66 TRIM28 KAT6A RAI1

3.35e-0495654PS50016
DomainZF_PHD_1

TRIM66 TRIM28 KAT6A RAI1

3.49e-0496654PS01359
DomainTIL

MUC19 MUC5AC

7.70e-0412652PF01826
DomainC8

MUC19 MUC5AC

7.70e-0412652PF08742
DomainUnchr_dom_Cys-rich

MUC19 MUC5AC

9.08e-0413652IPR014853
DomainC8

MUC19 MUC5AC

9.08e-0413652SM00832
DomainTIL_dom

MUC19 MUC5AC

1.06e-0314652IPR002919
DomainBbox_C

TRIM66 TRIM28

1.22e-0315652IPR003649
DomainBBC

TRIM66 TRIM28

1.22e-0315652SM00502
DomainVWD

MUC19 MUC5AC

1.39e-0316652SM00216
DomainVWF_type-D

MUC19 MUC5AC

1.39e-0316652IPR001846
DomainVWFD

MUC19 MUC5AC

1.39e-0316652PS51233
DomainVWD

MUC19 MUC5AC

1.39e-0316652PF00094
DomainWHTH_DNA-bd_dom

DVL1P1 KAT6A DVL1 DVL2 FOXI3

1.54e-03242655IPR011991
DomainCTCK_1

MUC19 MUC5AC

1.76e-0318652PS01185
DomainHTH_motif

HOXB3 NKX2-3 DLX5

1.79e-0369653IPR000047
DomainVWC_out

MUC19 MUC5AC

1.96e-0319652SM00215
DomainPHD

TRIM66 TRIM28 KAT6A

2.27e-0375653PF00628
DomainHomeobox_Antennapedia_CS

HOXB3 HOXB6

2.40e-0321652IPR001827
Domainzf-RanBP

TAF15 NUP153

2.63e-0322652PF00641
DomainCT

MUC19 MUC5AC

2.63e-0322652SM00041
DomainZnf_PHD-finger

TRIM66 TRIM28 KAT6A

2.63e-0379653IPR019787
DomainZnF_RBZ

TAF15 NUP153

2.88e-0323652SM00547
DomainZF_RANBP2_2

TAF15 NUP153

2.88e-0323652PS50199
DomainZF_RANBP2_1

TAF15 NUP153

3.13e-0324652PS01358
DomainANTENNAPEDIA

HOXB3 HOXB6

3.13e-0324652PS00032
DomainZnf_RanBP2

TAF15 NUP153

3.40e-0325652IPR001876
DomainCys_knot_C

MUC19 MUC5AC

3.40e-0325652IPR006207
DomainCTCK_2

MUC19 MUC5AC

3.40e-0325652PS01225
DomainbZIP_1

JUN CREB3L2

6.23e-0334652PF00170
PathwayREACTOME_KILLING_MECHANISMS

JUN DVL1 DVL2

8.49e-0612493M29844
PathwayREACTOME_NEGATIVE_REGULATION_OF_TCF_DEPENDENT_SIGNALING_BY_DVL_INTERACTING_PROTEINS

DVL1 DVL2

1.18e-045492M27447
PathwayREACTOME_ISG15_ANTIVIRAL_MECHANISM

FLNB EIF4G1 NUP214 NUP153

1.24e-0474494M48006
PathwayBIOCARTA_AGR_PATHWAY

JUN LAMA1 DVL1

1.66e-0431493MM1343
PathwayREACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES

FLNB EIF4G1 OASL NUP214 NUP153

1.72e-04151495M550
PathwayREACTOME_WNT_MEDIATED_ACTIVATION_OF_DVL

DVL1 DVL2

3.27e-048492M27100
PathwayWP_WNT_SIGNALING_AND_PLURIPOTENCY

JUN DVL1 DVL2 POU5F1

4.11e-04101494M39387
PathwayWP_WNT_SIGNALING_PATHWAY_AND_PLURIPOTENCY

JUN DVL1 DVL2 POU5F1

4.11e-04101494MM15829
PathwayREACTOME_WNT_MEDIATED_ACTIVATION_OF_DVL

DVL1 DVL2

4.20e-049492MM14792
PathwayWP_NOTCH_SIGNALING_WP268

DVL1 DVL2 NCSTN

5.05e-0445493M39571
PathwayWP_NOTCH_SIGNALING_PATHWAY

DVL1 DVL2 NCSTN

5.39e-0446493MM15971
PathwayPID_PS1_PATHWAY

JUN DVL1 NCSTN

5.39e-0446493M70
PathwayKEGG_NOTCH_SIGNALING_PATHWAY

DVL1 DVL2 NCSTN

5.75e-0447493M7946
PathwayWP_FOCAL_ADHESION

FLNB JUN LAMA1 BIRC3 ITGAV

6.14e-04199495M39402
PathwayKEGG_FOCAL_ADHESION

FLNB JUN LAMA1 BIRC3 ITGAV

6.14e-04199495M7253
PathwayBIOCARTA_NPC_PATHWAY

NUP214 NUP153

6.38e-0411492M22033
PathwayREACTOME_NUCLEAR_ENVELOPE_BREAKDOWN

LEMD2 NUP214 NUP153

8.18e-0453493M27212
PathwayKEGG_PATHWAYS_IN_CANCER

JUN LAMA1 DVL1 DVL2 BIRC3 ITGAV

8.70e-04325496M12868
PathwayWP_VITAMIN_B12_DISORDERS

TCN2 CUBN

9.01e-0413492M39778
PathwayWP_MFAP5MEDIATED_OVARIAN_CANCER_CELL_MOTILITY_AND_INVASIVENESS

JUN ITGAV

9.01e-0413492M39463
Pubmed

Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.

LENG8 ARID1B UBAP2L TRIM28 SEC16A DVL2 TMEM209 NUP214 CAPRIN1 HNRNPH1 HNRNPH2 NUP153

3.85e-11440661234244565
Pubmed

CHK2-BRCA1 tumor-suppressor axis restrains oncogenic Aurora-A kinase to ensure proper mitotic microtubule assembly.

FLNB SEC24C UBAP2L TRIM28 EIF4G1 SEC16A TAF15 NUP214 CAPRIN1 HNRNPH1 HNRNPH2 NUP153

1.45e-10494661226831064
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

YTHDF1 LENG8 HOXA13 JUN ARID1B UBAP2L TRIM28 CDK12 EIF4G1 SEC16A TAF15 NUP214 HNRNPH1 NUP153 RAI1

2.45e-10954661536373674
Pubmed

Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair.

FLNB SEC24C UBAP2L TRIM28 EIF4G1 SEC16A RANBP9 CLASP2 TAF15 CAPRIN1 HNRNPH1 HNRNPH2

5.03e-10551661234728620
Pubmed

Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.

YTHDF1 LENG8 ARID1B CDK12 TM9SF3 LEMD2 SEC16A TMEM209 NUP214 NUP153 RAI1

1.00e-09457661132344865
Pubmed

A census of human transcription factors: function, expression and evolution.

HOXA13 JUN HOXB3 HOXB6 OTX1 NKX2-3 DMRTA1 POU5F1 DLX5 RUNX3 FOXI3 IRX2 CREB3L2 CRX

1.36e-09908661419274049
Pubmed

cDNA characterization and chromosomal mapping of two human homologues of the Drosophila dishevelled polarity gene.

DVL1P1 DVL1 DVL2

2.61e-0846638817329
Pubmed

Human dishevelled genes constitute a DHR-containing multigene family.

DVL1P1 DVL1 DVL2

2.61e-0846639192851
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

FLNB SEC24C UBAP2L EIF4G1 OASL SEC16A TAF15 NUP214 CAPRIN1 NUP153 RAI1

3.96e-08653661122586326
Pubmed

PTPN14 regulates Roquin2 stability by tyrosine dephosphorylation.

YTHDF1 UBAP2L TRIM28 CDK12 EIF4G1 SEC16A CLASP2 TAF15 CAPRIN1 HNRNPH1 HNRNPH2

5.79e-08678661130209976
Pubmed

Impact of cytosine methylation on DNA binding specificities of human transcription factors.

HOXA13 JUN HOXB6 OTX1 NKX2-3 DMRTA1 POU5F1 DLX5 RUNX3 CRX

7.77e-08544661028473536
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

FLNB SEC24C UBAP2L TRIM28 TM9SF3 EIF4G1 SEC16A DVL2 NUP214 HNRNPH1 NUP153

8.95e-08708661139231216
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

JUN NOL4L SEC24C UBAP2L TRIM28 CDK12 EIF4G1 SEC16A NUP214 HNRNPH1 NUP153

2.18e-07774661115302935
Pubmed

New roles for the de-ubiquitylating enzyme OTUD4 in an RNA-protein network and RNA granules.

YTHDF1 LENG8 UBAP2L EIF4G1 NUP214 CAPRIN1 WNK4 HNRNPH1 HNRNPH2

2.26e-0746266931138677
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

SEC24C UBAP2L TRIM28 EIF4G1 SEC16A DVL2 RANBP9 CLASP2 TAF15 CAPRIN1 NUP153 RAI1

2.36e-07963661228671696
Pubmed

The PRMT5/WDR77 complex regulates alternative splicing through ZNF326 in breast cancer.

CDK12 SEC16A TAF15 CAPRIN1 HNRNPH1 HNRNPH2

3.79e-0714766628977470
Pubmed

Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.

FLNB SEC24C UBAP2L CDK12 DVL1 SEC16A DVL2 NUP214 HNRNPH2

4.23e-0749866936634849
Pubmed

The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.

FLNB UBAP2L EIF4G1 DVL1 SEC16A DVL2 NUP214

5.80e-0725666733397691
Pubmed

Circular RNA circPVT1 promotes nasopharyngeal carcinoma metastasis via the β-TrCP/c-Myc/SRSF1 positive feedback loop.

YTHDF1 UBAP2L EIF4G1 SEC16A CAPRIN1 HNRNPH1 NUP153

6.44e-0726066736199071
Pubmed

Spatiotemporal-resolved protein networks profiling with photoactivation dependent proximity labeling.

UBAP2L SEC16A DVL2 RANBP9 TAF15 CAPRIN1 HNRNPH1 HNRNPH2

8.99e-0739966835987950
Pubmed

Protein phosphatase 2Calpha dephosphorylates axin and activates LEF-1-dependent transcription.

FLNB DVL1 DVL2

1.07e-061166310644691
Pubmed

Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.

FLNB YIF1A UBAP2L EIF4G1 SEC16A DVL2 TMEM209 NUP214 NUP153

1.26e-0656866937774976
Pubmed

CRISPR activation screen identifies BCL-2 proteins and B3GNT2 as drivers of cancer resistance to T cell-mediated cytotoxicity.

UBAP2L TRIM28 TM9SF3 EIF4G1 SEC16A TAF15 CAPRIN1 HNRNPH1

1.27e-0641866835338135
Pubmed

Loss of TRIM31 promotes breast cancer progression through regulating K48- and K63-linked ubiquitination of p53.

YTHDF1 OTX1 UBAP2L SEC16A TAF15 CAPRIN1 HNRNPH1 HNRNPH2

1.34e-0642166834650049
Pubmed

Identification of Human Neuronal Protein Complexes Reveals Biochemical Activities and Convergent Mechanisms of Action in Autism Spectrum Disorders.

UBAP2L EIF4G1 SEC16A NUP214 CAPRIN1

1.45e-0610166526949739
Pubmed

The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation.

YTHDF1 ARID1B UBAP2L TRIM28 CDK12 RANBP9 TAF15 NCSTN CAPRIN1 HNRNPH1 HNRNPH2 NUP153

1.57e-061153661229845934
Pubmed

In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators.

YTHDF1 FLNB JUN UBAP2L TRIM28 CDK12 EIF4G1 CLASP2 CAPRIN1 HNRNPH2 NUP153

2.01e-06971661133306668
Pubmed

AIMP2-DX2 provides therapeutic interface to control KRAS-driven tumorigenesis.

UBAP2L TRIM28 NUP214 HNRNPH1 HNRNPH2 NUP153

2.29e-0620066635546148
Pubmed

ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure.

YTHDF1 FLNB SEC24C UBAP2L EIF4G1 CAPRIN1 HNRNPH2

2.31e-0631566726777405
Pubmed

Moz and retinoic acid coordinately regulate H3K9 acetylation, Hox gene expression, and segment identity.

HOXB3 HOXB6 KAT6A

2.34e-061466319922872
Pubmed

WWP2 ubiquitylates RNA polymerase II for DNA-PK-dependent transcription arrest and repair at DNA breaks.

ARID1B SEC24C UBAP2L TRIM28 EIF4G1 DVL2 TAF15 CAPRIN1 HNRNPH1

2.41e-0661566931048545
Pubmed

LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.

FLNB UBAP2L EIF4G1 SEC16A PARP14 CAPRIN1

2.42e-0620266633005030
Pubmed

Molecular Characterization of the Oncogene BTF3 and Its Targets in Colorectal Cancer.

FLNB UBAP2L TRIM28 LEMD2 EIF4G1 SEC16A RUNX3 CAPRIN1 HNRNPH1

2.78e-0662666933644029
Pubmed

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.

YTHDF1 FLNB JUN HOXB6 UBAP2L TRIM28 TAF15 CAPRIN1 HNRNPH1 HNRNPH2

2.79e-06807661022681889
Pubmed

Wnt regulation: exploring Axin-Disheveled interactions and defining mechanisms by which the SCF E3 ubiquitin ligase is recruited to the destruction complex.

SEC24C UBAP2L TRIM28 EIF4G1 RANBP9 TAF15 CAPRIN1 HNRNPH1 HNRNPH2 NUP153

2.86e-06809661032129710
Pubmed

Limited expression of nuclear pore membrane glycoprotein 210 in cell lines and tissues suggests cell-type specific nuclear pores in metazoans.

LAMA1 NUP214 NUP153

2.92e-061566314697343
Pubmed

A dynamic expression survey identifies transcription factors relevant in mouse digestive tract development.

HOXA13 HOXB3 HOXB6 DMRTA1 CUBN

3.13e-0611866516971476
Pubmed

A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.

JUN ARID1B CDK12 SEC16A DVL2 RANBP9 CAPRIN1 HNRNPH1

3.13e-0647266838943005
Pubmed

The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.

YTHDF1 FLNB SEC24C TRIM28 EIF4G1 CLASP2 NUP214 HNRNPH1 NUP153

3.24e-0663866933239621
Pubmed

The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.

FLNB JUN TRIM28 KAT6A EIF4G1 SEC16A PARP14

3.26e-0633266737433992
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

FLNB SEC24C UBAP2L TRIM28 EIF4G1 SEC16A TAF15 NUP214 HNRNPH1 HNRNPH2 NUP153

3.34e-061024661124711643
Pubmed

Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.

HOXA13 SEC24C TRIM28 EIF4G1 DVL1 SEC16A RANBP9 CLASP2 TAF15 NUP214 CAPRIN1 HNRNPH1

3.52e-061247661227684187
Pubmed

Endogenous authentic OCT4A proteins directly regulate FOS/AP-1 transcription in somatic cancer cells.

JUN POU5F1

3.55e-06266229789579
Pubmed

Human homologue sequences to the Drosophila dishevelled segment-polarity gene are deleted in the DiGeorge syndrome.

DVL1P1 DVL1

3.55e-0626628644734
Pubmed

c-Jun/AP-1 transcription factor regulates laminin-1-induced neurite outgrowth in human bone marrow mesenchymal stem cells: role of multiple signaling pathways.

JUN LAMA1

3.55e-06266221570970
Pubmed

Wnt-mediated relocalization of dishevelled proteins.

DVL1 DVL2

3.55e-0626628856345
Pubmed

Differential expression of two genes Oct-4 and MUC5AC associates with poor outcome in patients with gastric cancer.

POU5F1 MUC5AC

3.55e-06266228762513
Pubmed

Functional role of Runx3 in the regulation of aggrecan expression during cartilage development.

ACAN RUNX3

3.55e-06266223625810
Pubmed

Estrogen regulation of human with-no-lysine (K) kinase-4 gene expression involves AP-1 transcription factor.

JUN WNK4

3.55e-06266220943203
Pubmed

An improved smaller biotin ligase for BioID proximity labeling.

ARID1B EIF4G1 MUC19 NUP214 NUP153

3.83e-0612366526912792
Pubmed

SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation-Phosphorylation Cross-talk.

UBAP2L TRIM28 LEMD2 SEC16A TAF15 NUP214 CAPRIN1 HNRNPH1 NUP153

4.01e-0665566935819319
Pubmed

The functional interactome of PYHIN immune regulators reveals IFIX is a sensor of viral DNA.

LENG8 HOXA13 JUN LEMD2 CAPRIN1 NUP153 RAI1

4.52e-0634966725665578
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

JUN OTX1 TRIM28 LEMD2 TMEM209 TAF15 NUP214 HNRNPH1 HNRNPH2 NUP153 RAI1 CREB3L2

5.13e-061294661230804502
Pubmed

Posterior malformations in Dact1 mutant mice arise through misregulated Vangl2 at the primitive streak.

JUN DVL1 DVL2

5.22e-061866319701191
Pubmed

BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.

SEC24C UBAP2L TRIM28 TM9SF3 EIF4G1 SEC16A DVL2 TAF15 NUP214 HNRNPH1 HNRNPH2 NUP153

6.19e-061318661230463901
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

JUN TRIM28 CDK12 KAT6A EIF4G1 DVL1 SEC16A CLASP2 NUP214 ARHGAP33 RAI1

6.87e-061105661135748872
Pubmed

Host E3 ligase HUWE1 attenuates the proapoptotic activity of the MERS-CoV accessory protein ORF3 by promoting its ubiquitin-dependent degradation.

FLNB JUN TMEM209 NUP214 NCSTN HNRNPH1 HNRNPH2 NUP153

7.71e-0653466835032548
Pubmed

SLFN11 promotes CDT1 degradation by CUL4 in response to replicative DNA damage, while its absence leads to synthetic lethality with ATR/CHK1 inhibitors.

FLNB NUP214 PARP14 HNRNPH2 NUP153 FAN1

8.23e-0625066633536335
Pubmed

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.

YTHDF1 LENG8 SEC24C UBAP2L CDK12 EIF4G1 SEC16A CLASP2 TAF15 ITGAV MUC5AC CAPRIN1

9.20e-061371661236244648
Pubmed

SND1 binds SARS-CoV-2 negative-sense RNA and promotes viral RNA synthesis through NSP9.

YTHDF1 UBAP2L EIF4G1 CAPRIN1 HNRNPH1 HNRNPH2

9.84e-0625866637794589
Pubmed

Tumor suppressor BAP1 nuclear import is governed by transportin-1.

FLNB UBAP2L TRIM28 CDK12 EIF4G1 SEC16A RANBP9 CLASP2 CAPRIN1 HNRNPH1 NUP153

9.92e-061149661135446349
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

LENG8 UBAP2L TRIM28 CDK12 SEC16A DVL2 TAF15 NUP214 HNRNPH1 NUP153

1.01e-05934661033916271
Pubmed

Otx5 regulates genes that show circadian expression in the zebrafish pineal complex.

OTX1 CRX

1.06e-05366211753388
Pubmed

Inversin, the gene product mutated in nephronophthisis type II, functions as a molecular switch between Wnt signaling pathways.

DVL1 DVL2

1.06e-05366215852005
Pubmed

Differential mediation of the Wnt canonical pathway by mammalian Dishevelleds-1, -2, and -3.

DVL1 DVL2

1.06e-05366218093802
Pubmed

DVL mutations identified from human neural tube defects and Dandy-Walker malformation obstruct the Wnt signaling pathway.

DVL1 DVL2

1.06e-05366232900645
Pubmed

Essential role of the Dishevelled DEP domain in a Wnt-dependent human-cell-based complementation assay.

DVL1 DVL2

1.06e-05366227744318
Pubmed

Binding of APC and dishevelled mediates Wnt5a-regulated focal adhesion dynamics in migrating cells.

DVL1 DVL2

1.06e-05366220224554
Pubmed

Nkx2.3 transcription factor is a key regulator of mucous cell identity in salivary glands.

NKX2-3 MUC19

1.06e-05366238311164
Pubmed

CRX is a diagnostic marker of retinal and pineal lineage tumors.

OTX1 CRX

1.06e-05366219936203
Pubmed

Nucleoporins nup98 and nup214 participate in nuclear export of human immunodeficiency virus type 1 Rev.

NUP214 NUP153

1.06e-0536629847314
Pubmed

Regulation of polarized extension and planar cell polarity in the cochlea by the vertebrate PCP pathway.

DVL1 DVL2

1.06e-05366216116426
Pubmed

Heterogeneous nuclear ribonucleoproteins F and H/H' show differential expression in normal and selected cancer tissues.

HNRNPH1 HNRNPH2

1.06e-05366214980514
Pubmed

Heterogeneous nuclear ribonucleoproteins H, H', and F are members of a ubiquitously expressed subfamily of related but distinct proteins encoded by genes mapping to different chromosomes.

HNRNPH1 HNRNPH2

1.06e-0536627499401
Pubmed

Kap1 regulates the self-renewal of embryonic stem cells and cellular reprogramming by modulating Oct4 protein stability.

TRIM28 POU5F1

1.06e-05366232895487
Pubmed

Smad2 nucleocytoplasmic shuttling by nucleoporins CAN/Nup214 and Nup153 feeds TGFbeta signaling complexes in the cytoplasm and nucleus.

NUP214 NUP153

1.06e-05366212191473
Pubmed

The DIX domain targets dishevelled to actin stress fibres and vesicular membranes.

DVL1P1 DVL2

1.06e-05366212384700
Pubmed

Dishevelled proteins are significantly upregulated in chronic lymphocytic leukaemia.

DVL1 DVL2

1.06e-05366227086035
Pubmed

Nuclear Dvl, c-Jun, beta-catenin, and TCF form a complex leading to stabilization of beta-catenin-TCF interaction.

JUN DVL1

1.06e-05366218347071
Pubmed

Positive Feedback Loop of OCT4 and c-JUN Expedites Cancer Stemness in Liver Cancer.

JUN POU5F1

1.06e-05366227341307
Pubmed

Characterization of mouse dishevelled (Dvl) proteins in Wnt/Wingless signaling pathway.

DVL1 DVL2

1.06e-05366210409711
Pubmed

Dishevelled-3 C-terminal His single amino acid repeats are obligate for Wnt5a activation of non-canonical signaling.

DVL1 DVL2

1.06e-05366221092292
Pubmed

Mechanism of activation of the Formin protein Daam1.

DVL1 DVL2

1.06e-05366218162551
Pubmed

hnRNPs H, H' and F behave differently with respect to posttranslational cleavage and subcellular localization.

HNRNPH1 HNRNPH2

1.06e-05366210456323
Pubmed

Genomic organization of mouse Dishevelled genes.

DVL1 DVL2

1.06e-0536628973355
Pubmed

Dishevelled family proteins are expressed in non-small cell lung cancer and function differentially on tumor progression.

DVL1 DVL2

1.06e-05366218692936
Pubmed

The nuclear pore complex: a new dynamic in HIV-1 replication.

NUP214 NUP153

1.06e-05366221327100
Pubmed

beta-Arrestin1 modulates lymphoid enhancer factor transcriptional activity through interaction with phosphorylated dishevelled proteins.

DVL1 DVL2

1.06e-05366211742073
Pubmed

Heterogeneous nuclear ribonucleoprotein H1/H2-dependent unsplicing of thymidine phosphorylase results in anticancer drug resistance.

HNRNPH1 HNRNPH2

1.06e-05366221068389
Pubmed

Dishevelled proteins are associated with olfactory sensory neuron presynaptic terminals.

DVL1 DVL2

1.06e-05366223437169
Pubmed

Genetic variants in RUNX3, AMD1 and MSRA in the methionine metabolic pathway and survival in nonsmall cell lung cancer patients.

MSRA RUNX3

1.06e-05366230650190
Pubmed

RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.

LENG8 DVL1 SEC16A DVL2 TMEM209 NUP153

1.10e-0526366634702444
Pubmed

RC3H1 post-transcriptionally regulates A20 mRNA and modulates the activity of the IKK/NF-κB pathway.

UBAP2L TRIM28 EIF4G1 SEC16A CLASP2

1.22e-0515666526170170
Pubmed

The high-mobility-group domain of Sox proteins interacts with DNA-binding domains of many transcription factors.

JUN POU5F1 DLX5

1.28e-052466316582099
Pubmed

mTORC1 activity regulates post-translational modifications of glycine decarboxylase to modulate glycine metabolism and tumorigenesis.

FLNB UBAP2L EIF4G1 SEC16A CAPRIN1 HNRNPH1

1.38e-0527466634244482
Pubmed

Ubiquitin-assisted phase separation of dishevelled-2 promotes Wnt signalling.

DVL1P1 TRIM28 DVL1 DVL2 RANBP9

1.42e-0516166536398662
Pubmed

The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation.

HOXA13 JUN OTX1 SEC24C TRIM28 RUNX3 HNRNPH1 HNRNPH2

1.45e-0558366829844126
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

FLNB NOL4L DVL1 SEC16A DVL2 POU5F1 NUP214

1.46e-0541866734709266
Pubmed

The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.

YIF1A ARID1B OTX1 TRIM28 CDK12 TM9SF3 LEMD2 EIF4G1 TMEM209 NCSTN ITGAV

1.52e-051203661129180619
Pubmed

Fine mapping of human HOX gene clusters.

HOXA13 HOXB3 HOXB6

1.64e-05266638646877
InteractionNUMA1 interactions

TRIM28 KAT6A DVL1 DVL2 RANBP9 RIBC1 BIRC3 POU5F1 TAF15 NUP214 NCSTN CAPRIN1 NUP153 RAI1

2.89e-104696614int:NUMA1
InteractionNUP35 interactions

YTHDF1 LENG8 ARID1B TRIM28 CDK12 TM9SF3 LEMD2 SEC16A TMEM209 BIRC3 NUP214 NUP153 RAI1

9.80e-104246613int:NUP35
InteractionSIRT6 interactions

LENG8 FLNB ARID1B UBAP2L TRIM28 SEC16A DVL2 TMEM209 POU5F1 NUP214 CAPRIN1 HNRNPH1 HNRNPH2 NUP153

1.22e-086286614int:SIRT6
InteractionFAM120A interactions

YTHDF1 TRIM66 UBAP2L KAT6A OASL SEC16A TAF15 CAPRIN1 HNRNPH1 HNRNPH2

1.90e-073496610int:FAM120A
InteractionFXR1 interactions

YTHDF1 FLNB SEC24C UBAP2L TRIM28 EIF4G1 SEC16A RANBP9 BIRC3 CAPRIN1 HNRNPH1 HNRNPH2 NUP153

2.54e-076796613int:FXR1
InteractionSMC5 interactions

YTHDF1 LENG8 HOXA13 JUN ARID1B UBAP2L TRIM28 CDK12 EIF4G1 SEC16A TAF15 NUP214 HNRNPH1 NUP153 RAI1

6.09e-0710006615int:SMC5
InteractionPRMT1 interactions

YTHDF1 FLNB SEC24C UBAP2L TRIM28 EIF4G1 SEC16A RANBP9 BIRC3 CLASP2 TAF15 CAPRIN1 HNRNPH1 HNRNPH2

1.46e-069296614int:PRMT1
InteractionCCAR2 interactions

TRIM28 EIF4G1 OASL SEC16A DVL2 BIRC3 POU5F1 TAF15 HNRNPH1

1.47e-06337669int:CCAR2
InteractionNUP50 interactions

FLNB CDK12 EIF4G1 RANBP9 BIRC3 TAF15 NUP214 NUP153 RAI1

1.62e-06341669int:NUP50
InteractionTRIM33 interactions

JUN ARID1B UBAP2L TRIM28 EIF4G1 DVL2 POU5F1 TAF15 CAPRIN1 CRX

2.04e-064536610int:TRIM33
InteractionHNRNPM interactions

LENG8 FLNB JUN TRIM28 KAT6A EIF4G1 SEC16A BIRC3 POU5F1 TAF15 HNRNPH1 HNRNPH2

3.45e-067236612int:HNRNPM
InteractionWARS1 interactions

FLNB TRIM28 KAT6A EIF4G1 BIRC3 POU5F1 HNRNPH1

3.67e-06197667int:WARS1
InteractionSMARCC1 interactions

JUN ARID1B OTX1 TRIM28 BIRC3 POU5F1 TAF15 CAPRIN1 CRX

4.28e-06384669int:SMARCC1
InteractionSMAD2 interactions

HOXA13 JUN ARID1B TRIM28 DVL1 RANBP9 NUP214 RUNX3 NUP153

4.37e-06385669int:SMAD2
InteractionFUBP3 interactions

YTHDF1 UBAP2L TRIM28 SEC16A BIRC3 POU5F1 CAPRIN1 HNRNPH1

5.54e-06297668int:FUBP3
InteractionLARP4 interactions

YTHDF1 UBAP2L KAT6A EIF4G1 CAPRIN1 HNRNPH1 CRX

5.58e-06210667int:LARP4
InteractionG3BP2 interactions

YTHDF1 UBAP2L TRIM28 EIF4G1 RANBP9 BIRC3 NUP214 CAPRIN1 HNRNPH1 NUP153

6.69e-065186610int:G3BP2
InteractionCNOT1 interactions

YTHDF1 UBAP2L TRIM28 RIBC1 BIRC3 POU5F1 CAPRIN1 HNRNPH1

6.73e-06305668int:CNOT1
InteractionTCF20 interactions

JUN DVL2 POU5F1 HNRNPH1 RAI1 CRX

8.29e-06146666int:TCF20
InteractionRANGAP1 interactions

JUN TRIM28 KAT6A BIRC3 CLASP2 NUP214 HNRNPH1 NUP153

8.32e-06314668int:RANGAP1
InteractionNUP188 interactions

TRIM66 TRIM28 DVL2 BIRC3 NUP214 NUP153

8.96e-06148666int:NUP188
InteractionRFC4 interactions

TRIM28 DVL2 BIRC3 POU5F1 NCSTN CAPRIN1 FAN1

9.29e-06227667int:RFC4
InteractionBRCA1 interactions

FLNB JUN SEC24C UBAP2L TRIM28 EIF4G1 SEC16A RANBP9 TAF15 NUP214 CUBN CAPRIN1 HNRNPH1 HNRNPH2 NUP153

9.43e-0612496615int:BRCA1
InteractionRC3H2 interactions

YTHDF1 UBAP2L TRIM28 CDK12 EIF4G1 SEC16A CLASP2 TAF15 CAPRIN1 HNRNPH1 HNRNPH2

9.85e-066676611int:RC3H2
InteractionSOX10 interactions

JUN ARID1B POU5F1 DLX5 CRX

1.27e-0592665int:SOX10
InteractionGLUL interactions

YTHDF1 HOXB6 RANBP9 BIRC3 TAF15 HNRNPH1

1.40e-05160666int:GLUL
InteractionSMAD3 interactions

JUN ARID1B KAT6A DVL1 RANBP9 NUP214 RUNX3 NUP153 CRX

1.45e-05447669int:SMAD3
InteractionNAGK interactions

HOXB6 ARID1B DVL2 HNRNPH1 HNRNPH2 RAI1

1.50e-05162666int:NAGK
InteractionTOP3B interactions

YTHDF1 JUN UBAP2L TRIM28 CDK12 KAT6A EIF4G1 DVL1 SEC16A DVL2 CLASP2 TAF15 NUP214 CAPRIN1 ARHGAP33 RAI1

1.54e-0514706616int:TOP3B
InteractionAR interactions

LENG8 HOXA13 JUN ARID1B UBAP2L TRIM28 SEC16A RANBP9 POU5F1 TAF15 HNRNPH1 HNRNPH2 RAI1

1.66e-059926613int:AR
InteractionSMARCC2 interactions

JUN ARID1B TRIM28 POU5F1 TAF15 NCSTN CAPRIN1 NUP153

1.94e-05353668int:SMARCC2
InteractionZNF34 interactions

YTHDF1 LENG8 OTX1 TRIM28

1.99e-0549664int:ZNF34
InteractionKCNA3 interactions

FLNB SEC24C UBAP2L TRIM28 TM9SF3 LAMA1 EIF4G1 SEC16A DVL2 NUP214 HNRNPH1 NUP153

2.25e-058716612int:KCNA3
InteractionNCOR2 interactions

JUN SEC16A RANBP9 BIRC3 POU5F1 ITGAV CRX

2.46e-05264667int:NCOR2
InteractionPRRC2B interactions

YTHDF1 TRIM66 UBAP2L SEC16A POU5F1 CAPRIN1 CRX

2.52e-05265667int:PRRC2B
InteractionSIRT7 interactions

FLNB SEC24C UBAP2L EIF4G1 OASL SEC16A TAF15 NUP214 CAPRIN1 NUP153 RAI1

2.72e-057446611int:SIRT7
InteractionPPIA interactions

MSRA JUN ARID1B CDK12 SEC16A DVL2 RANBP9 BIRC3 POU5F1 CAPRIN1 HNRNPH1 NUP153

2.72e-058886612int:PPIA
InteractionLMNB1 interactions

HOXA13 JUN TRIM28 RANBP9 TMEM209 BIRC3 TAF15 NCSTN HNRNPH1 NUP153

2.75e-056106610int:LMNB1
InteractionLSM14B interactions

UBAP2L KAT6A POU5F1 CAPRIN1 HNRNPH1

2.90e-05109665int:LSM14B
InteractionALG13 interactions

YTHDF1 LENG8 TRIM66 ARID1B UBAP2L SEC16A

2.99e-05183666int:ALG13
InteractionSLFN11 interactions

TRIM66 FLNB EIF4G1 NUP214 PARP14 HNRNPH2 NUP153 FAN1

3.05e-05376668int:SLFN11
InteractionATN1 interactions

LENG8 KAT6A DVL1 DVL2 HNRNPH1 CRX

3.37e-05187666int:ATN1
InteractionARHGEF39 interactions

SEC16A DVL2 HNRNPH1 HNRNPH2

3.39e-0556664int:ARHGEF39
InteractionMEX3A interactions

FLNB JUN UBAP2L TRIM28 KAT6A EIF4G1 SEC16A PARP14

3.54e-05384668int:MEX3A
InteractionFAM120C interactions

YTHDF1 TRIM66 UBAP2L SEC16A CAPRIN1 HNRNPH1

3.80e-05191666int:FAM120C
InteractionFBL interactions

YTHDF1 LENG8 TRIM66 UBAP2L TRIM28 EIF4G1 SEC16A BIRC3 TAF15 CAPRIN1

4.07e-056396610int:FBL
InteractionKLF5 interactions

LENG8 JUN ARID1B SEC16A POU5F1 HNRNPH1

4.26e-05195666int:KLF5
InteractionMAPRE1 interactions

FLNB JUN EIF4G1 SEC16A BIRC3 CLASP2 NUP214 CAPRIN1 NUP153

4.33e-05514669int:MAPRE1
InteractionSOX2 interactions

YTHDF1 JUN ARID1B TRIM28 CDK12 LEMD2 OASL SEC16A RANBP9 POU5F1 TAF15 NUP214 CAPRIN1 HNRNPH1 HNRNPH2

4.34e-0514226615int:SOX2
InteractionETS2 interactions

JUN DVL2 POU5F1 HNRNPH1

4.76e-0561664int:ETS2
InteractionHCFC1 interactions

JUN UBAP2L TRIM28 BIRC3 POU5F1 TAF15 HNRNPH1

4.78e-05293667int:HCFC1
InteractionUBAP2L interactions

YTHDF1 UBAP2L TRIM28 BIRC3 POU5F1 CAPRIN1 HNRNPH1

5.32e-05298667int:UBAP2L
InteractionLRRC31 interactions

FLNB UBAP2L EIF4G1 SEC16A PARP14 CAPRIN1

5.63e-05205666int:LRRC31
InteractionZCCHC2 interactions

UBAP2L RANBP9 HNRNPH1

5.67e-0523663int:ZCCHC2
InteractionB3GNT2 interactions

UBAP2L TRIM28 TM9SF3 EIF4G1 SEC16A TAF15 ITGAV CAPRIN1 HNRNPH1

6.52e-05542669int:B3GNT2
InteractionRC3H1 interactions

YTHDF1 UBAP2L TRIM28 CDK12 EIF4G1 SEC16A CLASP2 CAPRIN1 HNRNPH1 HNRNPH2

6.61e-056776610int:RC3H1
InteractionRNF43 interactions

LENG8 DVL1 SEC16A DVL2 TMEM209 HNRNPH1 HNRNPH2 NUP153

7.46e-05427668int:RNF43
InteractionWWP2 interactions

ARID1B SEC24C UBAP2L TRIM28 EIF4G1 DVL1 DVL2 POU5F1 TAF15 CAPRIN1 HNRNPH1

8.14e-058406611int:WWP2
InteractionSMG7 interactions

YTHDF1 LENG8 TRIM66 ARID1B UBAP2L SEC16A CAPRIN1

8.16e-05319667int:SMG7
InteractionILK interactions

UBAP2L TRIM28 SEC16A RANBP9 POU5F1 ITGAV CAPRIN1

8.16e-05319667int:ILK
InteractionZNF598 interactions

FLNB UBAP2L TRIM28 EIF4G1 DVL2 CLASP2 CAPRIN1 HNRNPH1

8.49e-05435668int:ZNF598
InteractionPABPC1 interactions

YTHDF1 FLNB UBAP2L TRIM28 KAT6A EIF4G1 BIRC3 TAF15 CAPRIN1 HNRNPH1

8.62e-056996610int:PABPC1
InteractionMEX3B interactions

YTHDF1 UBAP2L SEC16A RIBC1 RUNX3 CAPRIN1

8.74e-05222666int:MEX3B
InteractionZNF326 interactions

TRIM28 KAT6A OASL BIRC3 TAF15 HNRNPH1

9.19e-05224666int:ZNF326
InteractionDDX5 interactions

FLNB TRIM28 KAT6A RANBP9 BIRC3 POU5F1 TAF15 HNRNPH1 HNRNPH2

9.32e-05568669int:DDX5
InteractionPABPC4 interactions

YTHDF1 UBAP2L TRIM28 EIF4G1 OASL TAF15 CAPRIN1 HNRNPH1

9.48e-05442668int:PABPC4
InteractionTLE5 interactions

YTHDF1 LENG8 DVL2 RIBC1 IRX2 HNRNPH1 HNRNPH2 CRX

9.63e-05443668int:TLE5
InteractionANKRD17 interactions

YTHDF1 HOXB6 UBAP2L TRIM28 POU5F1 CAPRIN1

9.65e-05226666int:ANKRD17
InteractionSMU1 interactions

TRIM28 CDK12 BIRC3 TAF15 NCSTN HNRNPH1

9.88e-05227666int:SMU1
InteractionCNOT10 interactions

YTHDF1 UBAP2L RIBC1 CAPRIN1 NUP153

9.90e-05141665int:CNOT10
InteractionAIMP2 interactions

FLNB UBAP2L TRIM28 EIF4G1 NUP214 HNRNPH1 HNRNPH2 NUP153

1.01e-04446668int:AIMP2
InteractionZNF789 interactions

TRIM28 HNRNPH1

1.05e-045662int:ZNF789
InteractionDVL1P1 interactions

DVL1P1 DVL2

1.05e-045662int:DVL1P1
InteractionPHLPP1 interactions

FLNB UBAP2L EIF4G1 DVL1 SEC16A DVL2 NUP214

1.07e-04333667int:PHLPP1
InteractionCNOT9 interactions

YTHDF1 UBAP2L SEC16A RIBC1 CAPRIN1 HNRNPH1

1.09e-04231666int:CNOT9
InteractionUPF1 interactions

YTHDF1 SEC24C UBAP2L TRIM28 OASL BIRC3 POU5F1 CAPRIN1 HNRNPH1

1.11e-04581669int:UPF1
InteractionTRIM31 interactions

YTHDF1 OTX1 UBAP2L SEC16A TAF15 CAPRIN1 HNRNPH1 HNRNPH2

1.14e-04454668int:TRIM31
InteractionSOX8 interactions

JUN POU5F1 DLX5

1.15e-0429663int:SOX8
InteractionCPSF7 interactions

YTHDF1 LENG8 UBAP2L SEC16A DVL2 BIRC3 CAPRIN1

1.17e-04338667int:CPSF7
InteractionMYCN interactions

YTHDF1 LENG8 HOXA13 ARID1B SEC24C UBAP2L TRIM28 CDK12 TAF15 RUNX3 CAPRIN1 HNRNPH1 HNRNPH2 RAI1

1.18e-0413736614int:MYCN
InteractionSUMO2 interactions

FLNB JUN UBAP2L TRIM28 EIF4G1 NUP214 HNRNPH1 HNRNPH2 NUP153

1.26e-04591669int:SUMO2
InteractionMIR206 interactions

NOL4L TAF15 HNRNPH1 HNRNPH2

1.31e-0479664int:MIR206
InteractionRPS7 interactions

UBAP2L KAT6A BIRC3 POU5F1 NCSTN CAPRIN1 HNRNPH1 NUP153

1.36e-04466668int:RPS7
InteractionZCCHC8 interactions

TRIM28 OASL POU5F1 TAF15 HNRNPH1

1.50e-04154665int:ZCCHC8
InteractionEWSR1 interactions

JUN OTX1 SEC24C UBAP2L CDK12 KAT6A RANBP9 POU5F1 TAF15 NCSTN HNRNPH1

1.59e-049066611int:EWSR1
InteractionITCH interactions

TRIM66 JUN UBAP2L DVL1 DVL2 POU5F1 TAF15

1.61e-04356667int:ITCH
InteractionASF1A interactions

LENG8 JUN ARID1B BIRC3 POU5F1 RAI1

1.64e-04249666int:ASF1A
InteractionIGF2BP2 interactions

YTHDF1 UBAP2L TRIM28 KAT6A OASL CAPRIN1 HNRNPH1

1.64e-04357667int:IGF2BP2
InteractionWDR77 interactions

CDK12 SEC16A BIRC3 TAF15 CAPRIN1 HNRNPH1 HNRNPH2

1.75e-04361667int:WDR77
InteractionRBPJ interactions

HOXA13 TRIM28 POU5F1 DLX5 RUNX3 HNRNPH1

1.82e-04254666int:RBPJ
InteractionHNRNPDL interactions

FLNB UBAP2L TRIM28 BIRC3 TAF15 HNRNPH1 HNRNPH2

1.85e-04364667int:HNRNPDL
InteractionSMARCB1 interactions

LENG8 JUN ARID1B TRIM28 KAT6A POU5F1 NCSTN

1.85e-04364667int:SMARCB1
InteractionL1TD1 interactions

TRIM28 KAT6A POU5F1

2.04e-0435663int:L1TD1
InteractionPML interactions

TRIM66 JUN UBAP2L TRIM28 KAT6A EIF4G1 SEC16A POU5F1 RUNX3 PARP14 CAPRIN1

2.05e-049336611int:PML
InteractionHTRA2 interactions

UBAP2L TRIM28 EIF4G1 TMEM209 BIRC3 HNRNPH1

2.11e-04261666int:HTRA2
InteractionDCTN1 interactions

YTHDF1 TRIM28 DVL1 SEC16A RANBP9 BIRC3 CLASP2 CAPRIN1

2.12e-04497668int:DCTN1
InteractionWDR5 interactions

FLNB UBAP2L TRIM28 KAT6A EIF4G1 BIRC3 POU5F1 TAF15 PARP14 CAPRIN1 HNRNPH1 HNRNPH2

2.12e-0411016612int:WDR5
InteractionCLUH interactions

UBAP2L EIF4G1 DVL1 DVL2 BIRC3 HNRNPH2

2.20e-04263666int:CLUH
InteractionKDM1A interactions

LENG8 FLNB NOL4L TRIM28 DVL1 SEC16A DVL2 RANBP9 BIRC3 POU5F1 NUP214

2.21e-049416611int:KDM1A
InteractionHDAC1 interactions

FLNB JUN TRIM28 DVL1 DVL2 RANBP9 BIRC3 POU5F1 NUP214 RUNX3 CAPRIN1 RAI1

2.25e-0411086612int:HDAC1
Cytoband17q21.3

HOXB3 HOXB6

2.41e-041666217q21.3
Cytoband6p21.31

LEMD2 POU5F1

1.61e-03416626p21.31
Cytoband1p36

DVL1 RUNX3

2.11e-03476621p36
GeneFamilyDishevelled segment polarity proteins|PDZ domain containing

DVL1 DVL2

2.31e-054362505
GeneFamilyHOXL subclass homeoboxes

HOXA13 HOXB3 HOXB6

1.50e-0452363518
GeneFamilyPHD finger proteins

TRIM66 TRIM28 KAT6A

7.56e-049036388
GeneFamilyZinc fingers RANBP2-type |RNA binding motif containing

TAF15 NUP153

7.90e-042136289
GeneFamilyCD molecules|Mucins

MUC19 MUC5AC

7.90e-0421362648
GeneFamilyNucleoporins

NUP214 NUP153

1.84e-03323621051
GeneFamilyBasic leucine zipper proteins

JUN CREB3L2

4.27e-0349362506
GeneFamilyNKL subclass homeoboxes and pseudogenes

NKX2-3 DLX5

7.86e-0367362519
GeneFamilyRNA binding motif containing

TAF15 HNRNPH1 HNRNPH2

8.65e-03213363725
GeneFamilyPRD class homeoboxes and pseudogenes

OTX1 CRX

1.44e-0292362521
GeneFamilyRing finger proteins|Tripartite motif containing|ARF GTPase family

TRIM66 TRIM28

1.53e-029536259
CoexpressionGSE3039_CD4_TCELL_VS_B1_BCELL_UP

FLNB TRIM28 CDK12 OASL SEC16A CREB3L2

1.04e-05200656M6466
CoexpressionSEIDEN_MET_SIGNALING

TM9SF3 ITGAV CAPRIN1

1.61e-0520653M16468
CoexpressionCHIBA_RESPONSE_TO_TSA_DN

BIRC3 ITGAV HNRNPH1

1.88e-0521653M12459
CoexpressionMARTINEZ_RB1_AND_TP53_TARGETS_UP

MSRA HOXB6 PILRA UBAP2L EIF4G1 DVL1 RANBP9 ITGAV CAPRIN1

2.23e-05623659M15896
CoexpressionMARTINEZ_TP53_TARGETS_UP

MSRA HOXB6 PILRA UBAP2L EIF4G1 DVL1 RANBP9 ITGAV CAPRIN1

2.26e-05624659M4371
CoexpressionMARTINEZ_RB1_AND_TP53_TARGETS_UP

MSRA HOXB6 PILRA UBAP2L EIF4G1 DVL1 RANBP9 ITGAV CAPRIN1

4.89e-05689659MM1041
CoexpressionMARTINEZ_TP53_TARGETS_UP

MSRA HOXB6 PILRA UBAP2L EIF4G1 DVL1 RANBP9 ITGAV CAPRIN1

5.17e-05694659MM1039
CoexpressionBENPORATH_SOX2_TARGETS

ARID1B CDK12 HIKESHI KAT6A DVL2 POU5F1 TAF15 IRX2 CAPRIN1

7.94e-05734659M3835
CoexpressionWANG_MLL_TARGETS

HOXA13 HOXB3 HOXB6 LAMA1 PARP14 WNK4

8.97e-05294656M2456
CoexpressionNAKAYA_PBMC_FLUARIX_FLUVIRIN_AGE_18_50YO_3DY_DN

YTHDF1 LENG8 NOL4L UBAP2L CDK12 CAPRIN1 NUP153

9.62e-05432657M41149
CoexpressionWANG_MLL_TARGETS

HOXA13 HOXB3 HOXB6 LAMA1 PARP14 WNK4

1.12e-04306656MM1076
CoexpressionVISALA_AGING_LYMPHOCYTE_UP

KAT6A TAF15

1.26e-047652M2050
CoexpressionGSE21033_CTRL_VS_POLYIC_STIM_DC_1H_UP

FLNB UBAP2L SYNGR3 ITGAV ARHGAP33

1.28e-04196655M7718
CoexpressionGSE21927_SPLENIC_C26GM_TUMOROUS_VS_4T1_TUMOR_MONOCYTES_DN

HIKESHI OASL ITGAV CAPRIN1 CREB3L2

1.28e-04196655M7590
CoexpressionGSE32423_CTRL_VS_IL7_MEMORY_CD8_TCELL_DN

PILRA DMRTA1 RUNX3 PARP14 CRX

1.34e-04198655M5084
CoexpressionGSE3994_WT_VS_PAC1_KO_ACTIVATED_MAST_CELL_DN

MSRA TRIM66 SEC24C LAMA1 CREB3L2

1.40e-04200655M6372
CoexpressionGSE38681_WT_VS_LYL1_KO_LYMPHOID_PRIMED_MULTIPOTENT_PROGENITOR_DN

KAT6A OASL BIRC3 PARP14 NUP153

1.40e-04200655M9020
CoexpressionGSE42724_NAIVE_VS_MEMORY_BCELL_DN

MSRA YTHDF1 KAT6A CLASP2 NUP153

1.40e-04200655M9793
CoexpressionGINESTIER_BREAST_CANCER_ZNF217_AMPLIFIED_DN

LENG8 UBAP2L LEMD2 TAF15 NUP214 RUNX3

1.92e-04338656M17094
ToppCellfacs-Tongue-nan-3m-Epithelial|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SIDT2 TM9SF3 CLASP2 CAPRIN1 HNRNPH1 HNRNPH2

4.91e-071986662f03f8897dd7cce6d8296638e14e11ec16bcf624
ToppCellfacs-Tongue-nan-3m|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SIDT2 TM9SF3 CLASP2 CAPRIN1 HNRNPH1 HNRNPH2

4.91e-07198666f2a4057f038ef7225a5b98a7ab068c30dff4eadd
ToppCellCOVID-19-COVID-19_Mild|COVID-19 / Disease, condition lineage and cell class

LENG8 ARID1B OASL RUNX3 PARP14 HNRNPH1

5.21e-0720066662c25042086f1afd1102e0720e933c2e476468fd
ToppCellCalu_3-infected|Calu_3 / Cell line, Condition and Strain

JUN CDK12 OASL BIRC3 PARP14

7.70e-061836658f7f5000645f24f20a8d7700c4df1f8953a1780b
ToppCellfacs-Brain_Myeloid-Striatum-3m-Myeloid-nan|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JUN TM9SF3 KAT6A CLASP2 ITGAV

9.01e-061896656dd4ec5ce4beb856f0d2d1654e3c4676d1d63736
ToppCellfacs-Brain_Myeloid-Striatum-3m-Myeloid|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JUN TM9SF3 KAT6A CLASP2 ITGAV

9.01e-061896653ae479ec7e00c57127cbe51a398329b10ca9848c
ToppCellfacs-Brain_Myeloid-Striatum-3m-Myeloid-microglial_cell|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JUN TM9SF3 KAT6A CLASP2 ITGAV

9.01e-06189665875df61ee48baa5142ba4d2427bdec1c53e5a828
ToppCellfacs-Brain_Myeloid-Striatum-3m|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JUN TM9SF3 KAT6A CLASP2 ITGAV

9.01e-0618966597ef5215d841ff366a3e3682cd9bd04100cbfde0
ToppCellfacs-Skin-Anagen-3m-Epithelial|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SIDT2 TRIM28 TM9SF3 IRX2 CAPRIN1

9.24e-06190665888ded899f0513d41bf655896d59ae8ef74e0978
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HOXB3 LAMA1 IRX2 WNK4 CREB3L2

9.24e-061906653dcadabbefe0128a5f30ab51234f049ab4d870c6
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HOXB3 LAMA1 IRX2 WNK4 CREB3L2

9.72e-06192665562df5e87038c500dd3a003fe5374cb31946b145
ToppCellfacs-Brain_Myeloid-Hippocampus-3m-Myeloid|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JUN TM9SF3 KAT6A CLASP2 ITGAV

9.97e-0619366506b65110db974f4ef90d3511ff34428976a52c9c
ToppCellfacs-Brain_Myeloid-Hippocampus-3m-Myeloid-microglial_cell|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JUN TM9SF3 KAT6A CLASP2 ITGAV

9.97e-061936659c16032bc03df8760ae199e8f19fdafa4c3f1827
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNB JUN EIF4G1 SEC16A HNRNPH1

9.97e-06193665471e65f02937bc18d7c5facdacdf1df58cf0f839
ToppCellfacs-Brain_Myeloid-Hippocampus-3m|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JUN TM9SF3 KAT6A CLASP2 ITGAV

9.97e-06193665a4f91bca5eaa985982d33a528f7566ffde154d47
ToppCellfacs-Brain_Myeloid-Hippocampus-3m-Myeloid-nan|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JUN TM9SF3 KAT6A CLASP2 ITGAV

9.97e-06193665b39d7feaac4ff8f7409cd3d15e8f3c6391367275
ToppCellfacs-Tongue-nan-3m-Epithelial-basal_cell_of_epidermis|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TM9SF3 CLASP2 CAPRIN1 HNRNPH1 HNRNPH2

1.13e-0519866522559b161e67b49fe8028bfaf861e069063599f5
ToppCellfacs-Tongue-nan-3m-Epithelial-nan|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TM9SF3 CLASP2 CAPRIN1 HNRNPH1 HNRNPH2

1.16e-051996658d50e1ee58710d896c0204937331d9f4dcd38de0
ToppCellIIH-CD4-antiviral_CD4|IIH / Condition, Cell_class and T cell subcluster

NOL4L LAMA1 OASL PARP14

6.91e-05148664ec626a44cea83f2a0e5c27fc8182f96446d297ac
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Myeloid-Monocytic-Nonclassical_Monocyte|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TCN2 PILRA TRIM28 SYNGR3

1.03e-0416466417d5b8bb7c015cf9f0d6e578a0d212eada39cb93
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LENG8 JUN SIDT2 WNK4

1.10e-04167664b94e8ee8c3fcebedd8fcd719eadddc04c7513c50
ToppCell(3)_Chondrocytes-(32)_Chondro-prehyper-2|World / Cell class and subclass of bone marrow stroma cells in homeostatis

ACAN DLX5 RUNX3 WNK4

1.41e-04178664c569a406c3ae183a278d8540e8eba58f4f26c5b0
ToppCell3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-B_cell-B_cells-B_cells_L.1.5.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SYNGR3 BIRC3 RUNX3 PARP14

1.50e-04181664d66838fca0429cad2079cd8d92a5cd33eb0d3522
ToppCellfacs-Marrow|facs / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MSRA JUN TCN2 PILRA

1.63e-04185664e40f0a0439834c3025d6c7832977be4e37a94c44
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

HOXB3 IRX2 WNK4 CREB3L2

1.74e-041886642ee64bc73a2251fd9f374be759b442cf4ed0d19e
ToppCellfacs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JUN EIF4G1 SEC16A ITGAV

1.74e-04188664a91443aa8fa8fa87f7501c59219daa0305bd0bbf
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51|PBMC_fresh-frozen / Compartment, severity and other cell annotations on 10x 3' data (130k)

LENG8 JUN NOL4L RUNX3

1.77e-041896640e8d1be3c406d1a393e18faccfe89116a8f82bcf
ToppCellfacs-Skin-Anagen-3m|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SIDT2 TRIM28 TM9SF3 CAPRIN1

1.81e-041906643466cebab16964e94da130d0673fa32e7d90b5ed
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

JUN ARID1B BIRC3 PARP14

1.81e-041906640724665ac8238f2383c3a929d89abf4a48ec2420
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_chondroblast_(18)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

ACAN DMRTA1 RUNX3 WNK4

1.85e-04191664273c4a757292a9301de0eaeacdec91c9866be229
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNB EIF4G1 SEC16A HNRNPH1

1.92e-04193664fe451b3295d77b2bd1ac25cf29310c85835a45fe
ToppCellmoderate-Myeloid-Monocyte-derived_Macrophage|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

SIDT2 TCN2 OASL PARP14

1.92e-0419366422455801194bd8c73c5c397f5eac4f723429c383
ToppCellfacs-Thymus-nan-3m|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

YTHDF1 SIDT2 TRIM28 CAPRIN1

1.96e-04194664f1661f9f2439fca5c1012c693b0744c4e3b90a9b
ToppCelldroplet-Pancreas-Endocrine-21m|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JUN EIF4G1 SEC16A HNRNPH1

1.96e-041946643a3ecedcdc7691cf21775818b598208fcb980c29
ToppCellCOVID-19_Severe-Non-classical_Monocyte-|COVID-19_Severe / Disease condition and Cell class

SIDT2 PILRA BIRC3 RUNX3

1.96e-04194664d70b9039fd2fef3e4be086513b94fb7e9bc1f670
ToppCellfacs-Thymus-nan|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

YTHDF1 SIDT2 TRIM28 CAPRIN1

1.96e-04194664cda1b197efb199330ea7ab25a7cee22cae22589d
ToppCellfacs-Thymus-nan-3m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

YTHDF1 SIDT2 TRIM28 CAPRIN1

1.96e-0419466466c056232ac216780acf4cc8ea325bd8ed1909c9
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JUN EIF4G1 SEC16A HNRNPH1

1.96e-041946640b023de48ed8a550d169bbe954881eb04bf4f981
ToppCellCOVID-19_Severe-Non-classical_Monocyte|COVID-19_Severe / Disease condition and Cell class

SIDT2 PILRA BIRC3 RUNX3

1.96e-041946645151546812678ae85cb22224084d27b29e3c4724
ToppCellcontrol-CD163+_Monocytes_(Sample_ID1_d7)|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

PILRA OASL NUP214 PARP14

2.00e-0419566419413dc6aa0010686cdfa0c750ef0a7a76caf308
ToppCellmoderate-Myeloid-Monocyte-derived_Macrophage|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

SIDT2 TCN2 OASL PARP14

2.00e-041956649c9634906168239cf978adb398787692437bf9e7
ToppCellNS-moderate-d_16-33-Myeloid-Monocyte-derived_Macrophage|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SIDT2 TCN2 OASL PARP14

2.00e-04195664d87c83d2d421c9291d0a10bc9db850e9fb337667
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Mesenchymal-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SIDT2 TM9SF3 HNRNPH1 HNRNPH2

2.04e-0419666466d76249bd2770cdddff2c1fe59a016e95da2124
ToppCellCOVID-19_Mild-Classical_Monocyte-cMono_4|COVID-19_Mild / Disease condition and Cell class

LENG8 OASL RUNX3 PARP14

2.04e-041966643729d1444c65cad640377894decc64129bc3fd5b
ToppCellEnterocyte-C_05|Enterocyte / shred on cell type and cluster

HOXA13 OASL BIRC3 PARP14

2.04e-04196664c307e5a70186567c62da938caa21749dc0e929d0
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Mesenchymal|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SIDT2 TM9SF3 HNRNPH1 HNRNPH2

2.04e-041966649bd4c146fc7555e32adfa393b3a07846eb826d25
ToppCellC_05|World / shred on cell type and cluster

HOXA13 OASL BIRC3 PARP14

2.04e-04196664bf4dfb460a153dbafb2b9b12b360c8757cec22cd
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SIDT2 TM9SF3 HNRNPH1 HNRNPH2

2.04e-04196664151f1a29a91f8b234e9b6ed062666357a2f69128
ToppCellControl-Myeloid-TRAM3|Control / Disease group,lineage and cell class (2021.01.30)

JUN PILRA OASL PARP14

2.08e-04197664733ff40039d67e561c2ded7c9bd0b4353101741e
ToppCellCOVID-19_Mild-Classical_Monocyte-cMono_4|Classical_Monocyte / Disease condition and Cell class

LENG8 OASL RUNX3 PARP14

2.08e-04197664e666f6580e9a20b5e550f02125706db17eec8510
ToppCellBAL-Control-Myeloid-TRAM-TRAM3|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

JUN PILRA OASL PARP14

2.08e-041976644416efdbd9c4ac3356a5dff2d535c2d7383376a9
ToppCellCOVID-19_Mild|World / Disease group, lineage and cell class

ARID1B OASL RUNX3 PARP14

2.08e-041976645c33454b10023decd2f5ccda9229b6512659711e
ToppCellBAL-Control-Myeloid-TRAM-TRAM3-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

JUN PILRA OASL PARP14

2.08e-04197664e131634bc67e0bd31a938a8e8df8dc752e1d0f47
ToppCellControl-Control-Lymphocyte-T/NK-NK_activated|Control / Disease, condition lineage and cell class

OASL SEC16A RIBC1 RUNX3

2.12e-0419866476d5fe4e5bbe6c73a6ca409b80b5c3924e07cab7
ToppCellPBMC-Mild|PBMC / Location, Disease Group, Cell group, Cell class (2021.03.09)

ARID1B OASL RUNX3 PARP14

2.12e-0419866444417089b62056269cac38d3134ff209c05b7007
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c5-CD16|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SIDT2 TCN2 PILRA OASL

2.12e-04198664e2038d9239e23d670d539f1c58475fd0de028e51
ToppCellPBMC-Mild|PBMC / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ARID1B OASL RUNX3 PARP14

2.12e-0419866428ef3fc4c17dcb765537b75917f7db78baa522db
ToppCellBAL-Mild-cDC_1|Mild / Compartment, Disease Groups and Clusters

SIDT2 PILRA OASL PARP14

2.16e-04199664c55181bdec8952b54198f0d4c9c5c84265b16572
ToppCellfacs-Lung-18m|Lung / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

JUN TCN2 EIF4G1 HNRNPH2

2.16e-04199664c11e0044d3cc37f6bb26df033ad4448b419addfc
ToppCellmild-CD163+_Monocytes_(Sample_ID1_d7)|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

TCN2 PILRA OASL PARP14

2.20e-0420066482126e25bfd8fba78dc1348fa5ad6a576289a139
ToppCell343B-Myeloid-Monocyte-CD16+_Monocyte|Monocyte / Donor, Lineage, Cell class and subclass (all cells)

JUN YIF1A SIDT2 PILRA

2.20e-04200664360728fbd3722e24c8c4fef5b19169d0a736ea52
ToppCellBronchial-10x5prime-Stromal-Peri/Epineurial_-NAF_endoneurial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

HOXB3 ACAN CUBN WNK4

2.20e-0420066429054cf55e88e1ac81a562d8dd9af9b7c749321d
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

ARID1B BIRC3 PARP14 HNRNPH1

6.38e-0550474GAVISH_3CA_METAPROGRAM_B_CELLS_B_CELLS_1
DiseaseAnemia, Megaloblastic

TCN2 CUBN

4.76e-055652C0002888
DiseaseDiGeorge syndrome (is_implicated_in)

DVL1P1 DVL1

4.76e-055652DOID:11198 (is_implicated_in)
Diseaseischemia (implicated_via_orthology)

ARID1B ITGAV

6.36e-0417652DOID:326 (implicated_via_orthology)
Diseaseglucose homeostasis measurement, acute insulin response measurement

YIF1A DMRTA1

7.15e-0418652EFO_0006831, EFO_0006896
Diseaseacute myeloid leukemia (is_implicated_in)

KAT6A NUP214 ITGAV

8.56e-0484653DOID:9119 (is_implicated_in)
DiseaseColorectal Carcinoma

TNNI3K TCN2 TRIM28 LAMA1 EIF4G1 DMRTA1 CUBN

8.81e-04702657C0009402
Diseaseglaucoma (is_marker_for)

JUN MUC5AC

8.85e-0420652DOID:1686 (is_marker_for)
DiseaseSjogren's syndrome (is_marker_for)

MUC19 MUC5AC

1.28e-0324652DOID:12894 (is_marker_for)
Diseaseforced expiratory volume

HOXB3 HOXB6 NOL4L OTX1 SEC24C CDK12 ACAN

1.73e-03789657EFO_0004314
Diseaseobesity

TRIM66 HOXB3 TNNI3K LEMD2

1.99e-03241654EFO_0001073
Diseasephysical activity measurement, body mass index

TRIM66 TNNI3K LEMD2

2.06e-03114653EFO_0004340, EFO_0008002

Protein segments in the cluster

PeptideGeneStartEntry
SPSGASYGQDYDLSP

CDK12

236

Q9NYV4
PGTENSGYFRGSYSN

BIRC3

126

Q13489
SGYFRGSYSNSPSNP

BIRC3

131

Q13489
PEFNNYYGSAAPASG

ARID1B

311

Q8NFD5
YDGYRPSFSNTPNSG

CAPRIN1

636

Q14444
DYYSPTGGAPHGYCS

DLX5

46

P56178
PPYHELSSYTYGGGS

DVL2

566

O14641
SFCSSGTGQPYGPTF

RANBP9

261

Q96S59
YPSYEGGAGTPSGTA

RAI1

56

Q7Z5J4
GGEQQSYSTYGNPGS

TAF15

11

Q92804
TQVGFAGGYTSNPTY

MSRA

91

Q9UJ68
PNDGFGVYSNSYGPE

NCSTN

141

Q92542
SYYSPFPASTSGGQS

FOXI3

381

A8MTJ6
QPASGSAYATPGAYG

LEMD2

91

Q8NC56
ASFLPSESGPYGYSN

JUN

16

P05412
AGPATGQAYGPHTYT

LENG8

196

Q96PV6
VNYPNSGSVSAYGPG

FLNB

1816

O75369
SSYGGPASQQLSGGY

HNRNPH2

406

P55795
PPGGFFYGSSSSGDS

MUC19

136

Q7Z5P9
QPDAFSSGGGSKPSY

NUP214

1251

P35658
GPSNPSYCYGNDSAS

MUC5AC

5226

P98088
SSYGGPASQQLSGGY

HNRNPH1

406

P31943
PASSYSQDPVYANGG

NOL4L

321

Q96MY1
SGSAFSPYPGSAAFT

IRX2

41

Q9BZI1
YGQGYPTPSSSYFGG

OTX1

231

P32242
AEIGSSLPSGAYYGS

ACAN

1911

P16112
GTPGYGSPHFTALYS

POU5F1

321

Q01860
PDGGSYAYAINPNSF

OASL

441

Q15646
SYPGNTYTDTGLPSY

PRR27

61

Q6MZM9
GPGQDKGFATSSYYP

HOXB6

46

P17509
QGFYGTVSSPDSGVY

PARP14

1206

Q460N5
SGPDSGGNPFYSTSA

PGBD5

36

Q8N414
PGDFGAGSYSQPSAT

KAT6A

1736

Q92794
PSGSTGSGPSYLYGV

PILRA

21

Q9UKJ1
YYEIGASEGSPYSGP

ARHGAP33

1086

O14559
YGDRGSFTSPGYPGT

CUBN

3516

O60494
GGSVYFSYPDSNGMP

HIKESHI

51

Q53FT3
DSPAEYSGPEGSYFG

ITGAV

36

P06756
SASYGGDSSLYGVNP

DMRTA1

416

Q5VZB9
AAALFGGYSSYPGSN

HOXB3

11

P14651
PGASPTEFGTYAGAY

EIF4G1

131

Q04637
PAYQDPGFSYGSGST

DVL1

551

O14640
PAYQDPGFSYGSGST

DVL1P1

526

P54792
GSFPNSGLYGSYPQG

SEC24C

171

P53992
PSAQAYGAPYSVGAS

NKX2-3

241

Q8TAU0
SAYGSPSSYFSGLDP

CRX

206

O43186
FGSFFQGYGPYPSAT

CREB3L2

391

Q70SY1
SSCNGPGQTTGHPYY

FAN1

361

Q9Y2M0
NPSPYHLYYGTSSGS

RUNX3

326

Q13761
DSFPGSSPYEGYNYG

SIDT2

346

Q8NBJ9
CSSSYYGNPQTPGGS

LAMA1

1491

P25391
QSSSGPAALPYGYFG

HOXA13

161

P31271
GGFTYETQASLSGPY

TCN2

366

P20062
VYGASGPGYGISQSS

CLASP2

566

O75122
FDDTSGGYSSQPGGY

YIF1A

26

O95070
ATPFQQPSGYGSHGY

UBAP2L

951

Q14157
NTYPGPASLQYFSGE

RIBC1

131

Q8N443
NFSSGPGFPEYGYPA

SEC16A

1411

O15027
STGASQAYPGYPVGS

SYNGR3

186

O43761
DSPFYPGKTTYGGAA

NUP153

256

P49790
SYSPGVTYSPVSGYN

TMEM209

176

Q96SK2
VYAATSPVNGYFGGS

TM9SF3

331

Q9HD45
DAPAYGGLQGSSPFY

TRIM66

276

O15016
YSQPGGDGSYVSVPS

TNNI3K

416

Q59H18
GPGSDFSPGDSYASD

WNK4

631

Q96J92
QEGYGFGSGDDPYSS

TRIM28

446

Q13263
AYGSSYTYPPSSLGG

YTHDF1

146

Q9BYJ9