| Category | Name | IntersectionWithQuery | PValue | GenesInTerm | GenesInQuery | GenesInTermInQuery | ID |
|---|---|---|---|---|---|---|---|
| GeneOntologyMolecularFunction | voltage-gated sodium channel activity | 2.36e-09 | 26 | 179 | 7 | GO:0005248 | |
| GeneOntologyMolecularFunction | monoatomic cation channel activity | CACNA1F CACNA1S HTR3E GRIN2A ANO10 KCNG3 HCN2 CATSPER1 NALCN KCNJ1 SCN1A SCN3A SCN5A SCN7A CACNA1G SEC61A1 KCNT1 | 1.37e-08 | 343 | 179 | 17 | GO:0005261 |
| GeneOntologyMolecularFunction | monoatomic cation transmembrane transporter activity | CACNA1F CACNA1S TMEM94 HTR3E GRIN2A ANO10 KCNG3 HCN2 CATSPER1 SLC11A1 NALCN SLC15A1 KCNJ1 SCN1A SCN3A ATP6V0A4 SCN5A SCN7A CACNA1G SEC61A1 ATP2A2 ATP2B4 KCNT1 | 3.06e-08 | 664 | 179 | 23 | GO:0008324 |
| GeneOntologyMolecularFunction | monoatomic ion channel activity | CACNA1F CACNA1S ANO2 CFTR HTR3E GRIN2A ANO10 KCNG3 HCN2 CATSPER1 NALCN KCNJ1 SCN1A SCN3A SCN5A SCN7A CACNA1G SEC61A1 KCNT1 | 3.36e-08 | 459 | 179 | 19 | GO:0005216 |
| GeneOntologyMolecularFunction | metal ion transmembrane transporter activity | CACNA1F CACNA1S TMEM94 GRIN2A KCNG3 HCN2 CATSPER1 SLC11A1 NALCN KCNJ1 SCN1A SCN3A SCN5A SCN7A CACNA1G SEC61A1 ATP2A2 ATP2B4 KCNT1 | 4.13e-08 | 465 | 179 | 19 | GO:0046873 |
| GeneOntologyMolecularFunction | monoatomic ion transmembrane transporter activity | CACNA1F CACNA1S ANO2 TMEM94 CFTR HTR3E GRIN2A ANO10 KCNG3 HCN2 CATSPER1 SLC11A1 NALCN SLC15A1 KCNJ1 SCN1A SCN3A ATP6V0A4 SCN5A SCN7A CACNA1G SEC61A1 ATP2A2 ATP2B4 KCNT1 | 4.58e-08 | 793 | 179 | 25 | GO:0015075 |
| GeneOntologyMolecularFunction | channel activity | CACNA1F CACNA1S ANO2 CFTR HTR3E BCL2A1 GRIN2A ANO10 KCNG3 HCN2 CATSPER1 NALCN KCNJ1 SCN1A SCN3A SCN5A SCN7A CACNA1G SEC61A1 KCNT1 | 5.63e-08 | 525 | 179 | 20 | GO:0015267 |
| GeneOntologyMolecularFunction | passive transmembrane transporter activity | CACNA1F CACNA1S ANO2 CFTR HTR3E BCL2A1 GRIN2A ANO10 KCNG3 HCN2 CATSPER1 NALCN KCNJ1 SCN1A SCN3A SCN5A SCN7A CACNA1G SEC61A1 KCNT1 | 5.81e-08 | 526 | 179 | 20 | GO:0022803 |
| GeneOntologyMolecularFunction | transmembrane transporter activity | CACNA1F CACNA1S ANO2 TMEM94 CFTR HTR3E BCL2A1 GRIN2A ANO10 KCNG3 HCN2 ABCA8 SEC61A2 CATSPER1 SLC11A1 NALCN SLC15A1 KCNJ1 SCN1A SCN3A ATP6V0A4 SCN5A SCN7A CACNA1G AP4M1 SEC61A1 ATP2A2 TAP1 ATP2B4 KCNT1 SLC38A8 | 6.22e-08 | 1180 | 179 | 31 | GO:0022857 |
| GeneOntologyMolecularFunction | inorganic molecular entity transmembrane transporter activity | CACNA1F CACNA1S ANO2 TMEM94 CFTR GRIN2A ANO10 KCNG3 HCN2 CATSPER1 SLC11A1 NALCN SLC15A1 KCNJ1 SCN1A SCN3A ATP6V0A4 SCN5A SCN7A CACNA1G SEC61A1 ATP2A2 ATP2B4 KCNT1 | 8.08e-08 | 758 | 179 | 24 | GO:0015318 |
| GeneOntologyMolecularFunction | inorganic cation transmembrane transporter activity | CACNA1F CACNA1S TMEM94 GRIN2A KCNG3 HCN2 CATSPER1 SLC11A1 NALCN SLC15A1 KCNJ1 SCN1A SCN3A ATP6V0A4 SCN5A SCN7A CACNA1G SEC61A1 ATP2A2 ATP2B4 KCNT1 | 2.23e-07 | 627 | 179 | 21 | GO:0022890 |
| GeneOntologyMolecularFunction | gated channel activity | CACNA1F CACNA1S ANO2 CFTR HTR3E GRIN2A ANO10 KCNG3 HCN2 CATSPER1 KCNJ1 SCN1A SCN7A CACNA1G KCNT1 | 3.59e-07 | 334 | 179 | 15 | GO:0022836 |
| GeneOntologyMolecularFunction | sodium channel activity | 3.94e-07 | 52 | 179 | 7 | GO:0005272 | |
| GeneOntologyMolecularFunction | transporter activity | CACNA1F CACNA1S ANO2 TMEM94 CFTR HTR3E BCL2A1 GRIN2A ANO10 KCNG3 HCN2 ABCA8 SEC61A2 CATSPER1 SLC11A1 NALCN SLC15A1 KCNJ1 SCN1A SCN3A ATP6V0A4 SCN5A SCN7A CACNA1G AP4M1 SEC61A1 ATP2A2 TAP1 ATP2B4 KCNT1 SLC38A8 | 4.36e-07 | 1289 | 179 | 31 | GO:0005215 |
| GeneOntologyMolecularFunction | voltage-gated monoatomic ion channel activity | CACNA1F CACNA1S GRIN2A KCNG3 HCN2 CATSPER1 KCNJ1 SCN1A CACNA1G KCNT1 | 5.90e-06 | 182 | 179 | 10 | GO:0005244 |
| GeneOntologyMolecularFunction | voltage-gated channel activity | CACNA1F CACNA1S GRIN2A KCNG3 HCN2 CATSPER1 KCNJ1 SCN1A CACNA1G KCNT1 | 6.49e-06 | 184 | 179 | 10 | GO:0022832 |
| GeneOntologyMolecularFunction | voltage-gated monoatomic cation channel activity | CACNA1F CACNA1S GRIN2A KCNG3 HCN2 CATSPER1 KCNJ1 CACNA1G KCNT1 | 9.55e-06 | 152 | 179 | 9 | GO:0022843 |
| GeneOntologyMolecularFunction | ATP-dependent activity | TMEM94 CFTR XRCC5 ABCA8 DMC1 MLH3 DNAH17 ATP6V0A4 AFG3L2 HSP90AB2P ATP2A2 DNAH8 TAP1 ATP2B4 HSP90AA1 HSP90AA2P HSP90AB1 TDRD12 | 1.09e-05 | 614 | 179 | 18 | GO:0140657 |
| GeneOntologyMolecularFunction | ATP hydrolysis activity | CFTR XRCC5 ABCA8 DMC1 MLH3 AFG3L2 HSP90AB2P ATP2A2 DNAH8 TAP1 ATP2B4 HSP90AA1 HSP90AA2P HSP90AB1 TDRD12 | 1.09e-05 | 441 | 179 | 15 | GO:0016887 |
| GeneOntologyMolecularFunction | peptidyltransferase activity | 1.39e-05 | 6 | 179 | 3 | GO:0000048 | |
| GeneOntologyMolecularFunction | leukotriene-C(4) hydrolase | 1.39e-05 | 6 | 179 | 3 | GO:0002951 | |
| GeneOntologyMolecularFunction | leukotriene C4 gamma-glutamyl transferase activity | 3.84e-05 | 8 | 179 | 3 | GO:0103068 | |
| GeneOntologyMolecularFunction | ATPase-coupled transmembrane transporter activity | 5.71e-05 | 109 | 179 | 7 | GO:0042626 | |
| GeneOntologyMolecularFunction | glutathione hydrolase activity | 5.72e-05 | 9 | 179 | 3 | GO:0036374 | |
| GeneOntologyMolecularFunction | ligand-gated monoatomic ion channel activity | 6.31e-05 | 193 | 179 | 9 | GO:0015276 | |
| GeneOntologyMolecularFunction | calcium ion transmembrane transporter activity | CACNA1F CACNA1S GRIN2A CATSPER1 CACNA1G SEC61A1 ATP2A2 ATP2B4 | 6.66e-05 | 151 | 179 | 8 | GO:0015085 |
| GeneOntologyMolecularFunction | ligand-gated channel activity | 7.39e-05 | 197 | 179 | 9 | GO:0022834 | |
| GeneOntologyMolecularFunction | CTP binding | 7.99e-05 | 2 | 179 | 2 | GO:0002135 | |
| GeneOntologyMolecularFunction | nitric-oxide synthase regulator activity | 8.12e-05 | 10 | 179 | 3 | GO:0030235 | |
| GeneOntologyMolecularFunction | calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity | 2.38e-04 | 3 | 179 | 2 | GO:0048101 | |
| GeneOntologyMolecularFunction | calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity | 2.38e-04 | 3 | 179 | 2 | GO:0004117 | |
| GeneOntologyMolecularFunction | sulfonylurea receptor binding | 2.38e-04 | 3 | 179 | 2 | GO:0017098 | |
| GeneOntologyMolecularFunction | high voltage-gated calcium channel activity | 2.40e-04 | 14 | 179 | 3 | GO:0008331 | |
| GeneOntologyMolecularFunction | ligand-gated monoatomic cation channel activity | 2.73e-04 | 140 | 179 | 7 | GO:0099094 | |
| GeneOntologyMolecularFunction | P-type transmembrane transporter activity | 2.94e-04 | 36 | 179 | 4 | GO:0140358 | |
| GeneOntologyMolecularFunction | P-type ion transporter activity | 2.94e-04 | 36 | 179 | 4 | GO:0015662 | |
| GeneOntologyMolecularFunction | omega peptidase activity | 3.64e-04 | 16 | 179 | 3 | GO:0008242 | |
| GeneOntologyMolecularFunction | disordered domain specific binding | 4.02e-04 | 39 | 179 | 4 | GO:0097718 | |
| GeneOntologyMolecularFunction | ATP-dependent protein folding chaperone | 4.44e-04 | 40 | 179 | 4 | GO:0140662 | |
| GeneOntologyMolecularFunction | UTP binding | 4.74e-04 | 4 | 179 | 2 | GO:0002134 | |
| GeneOntologyMolecularFunction | olfactory receptor activity | OR5T1 OR5B2 OR1S2 OR5T2 OR2S2 OR6C68 OR2T11 OR1J2 OR10G7 OR5J2 OR10G9 OR4X1 | 5.32e-04 | 431 | 179 | 12 | GO:0004984 |
| GeneOntologyMolecularFunction | ribonucleoside triphosphate phosphatase activity | CFTR XRCC5 ABCA8 DMC1 MLH3 AFG3L2 MFN2 GNAI2 HSP90AB2P ATP2A2 DNAH8 TAP1 ATP2B4 HSP90AA1 HSP90AA2P HSP90AB1 TDRD12 | 6.23e-04 | 775 | 179 | 17 | GO:0017111 |
| GeneOntologyMolecularFunction | threonine-type peptidase activity | 7.22e-04 | 20 | 179 | 3 | GO:0070003 | |
| GeneOntologyMolecularFunction | voltage-gated calcium channel activity | 7.60e-04 | 46 | 179 | 4 | GO:0005245 | |
| GeneOntologyMolecularFunction | pyrimidine ribonucleotide binding | 7.85e-04 | 5 | 179 | 2 | GO:0032557 | |
| GeneOntologyMolecularFunction | dATP binding | 7.85e-04 | 5 | 179 | 2 | GO:0032564 | |
| GeneOntologyMolecularFunction | sodium ion transmembrane transporter activity | 9.03e-04 | 171 | 179 | 7 | GO:0015081 | |
| GeneOntologyMolecularFunction | protein domain specific binding | DOCK3 CFTR HNRNPM BCL2A1 ACTN1 HCN2 PMEPA1 MUC17 ELMO2 SCN5A HSP90AB2P AP4M1 TRIM16L ATP2B4 HSP90AA1 SON HSP90AA2P HSP90AB1 | 9.06e-04 | 875 | 179 | 18 | GO:0019904 |
| GeneOntologyMolecularFunction | transmembrane transporter binding | 9.35e-04 | 172 | 179 | 7 | GO:0044325 | |
| GeneOntologyMolecularFunction | calcium channel activity | 1.09e-03 | 129 | 179 | 6 | GO:0005262 | |
| GeneOntologyMolecularFunction | primary active transmembrane transporter activity | 1.14e-03 | 178 | 179 | 7 | GO:0015399 | |
| GeneOntologyMolecularFunction | adenyl deoxyribonucleotide binding | 1.17e-03 | 6 | 179 | 2 | GO:0032558 | |
| GeneOntologyMolecularFunction | pyrophosphatase activity | CFTR XRCC5 ABCA8 DMC1 MLH3 AFG3L2 MFN2 GNAI2 HSP90AB2P ATP2A2 DNAH8 TAP1 ATP2B4 HSP90AA1 HSP90AA2P HSP90AB1 TDRD12 | 1.48e-03 | 839 | 179 | 17 | GO:0016462 |
| GeneOntologyMolecularFunction | hydrolase activity, acting on acid anhydrides | CFTR XRCC5 ABCA8 DMC1 MLH3 AFG3L2 MFN2 GNAI2 HSP90AB2P ATP2A2 DNAH8 TAP1 ATP2B4 HSP90AA1 HSP90AA2P HSP90AB1 TDRD12 | 1.50e-03 | 840 | 179 | 17 | GO:0016817 |
| GeneOntologyMolecularFunction | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | CFTR XRCC5 ABCA8 DMC1 MLH3 AFG3L2 MFN2 GNAI2 HSP90AB2P ATP2A2 DNAH8 TAP1 ATP2B4 HSP90AA1 HSP90AA2P HSP90AB1 TDRD12 | 1.50e-03 | 840 | 179 | 17 | GO:0016818 |
| GeneOntologyMolecularFunction | scaffold protein binding | 1.51e-03 | 93 | 179 | 5 | GO:0097110 | |
| GeneOntologyMolecularFunction | GTPase binding | DOCK2 DOCK3 KNTC1 NCKAP1 XPO4 RABGAP1 FARP1 MFN2 DENND5A HSP90AA1 | 1.57e-03 | 360 | 179 | 10 | GO:0051020 |
| GeneOntologyMolecularFunction | alkali metal ion binding | 1.58e-03 | 26 | 179 | 3 | GO:0031420 | |
| GeneOntologyMolecularFunction | purine deoxyribonucleotide binding | 1.63e-03 | 7 | 179 | 2 | GO:0032554 | |
| GeneOntologyMolecularFunction | catalytic activity, acting on a tRNA | 1.92e-03 | 144 | 179 | 6 | GO:0140101 | |
| GeneOntologyMolecularFunction | protein transmembrane transporter activity | 1.97e-03 | 28 | 179 | 3 | GO:0008320 | |
| GeneOntologyMolecularFunction | TPR domain binding | 2.16e-03 | 8 | 179 | 2 | GO:0030911 | |
| GeneOntologyMolecularFunction | ATPase-coupled monoatomic cation transmembrane transporter activity | 2.32e-03 | 62 | 179 | 4 | GO:0019829 | |
| GeneOntologyMolecularFunction | small GTPase binding | 2.51e-03 | 321 | 179 | 9 | GO:0031267 | |
| GeneOntologyMolecularFunction | monoatomic ion-gated channel activity | 2.65e-03 | 31 | 179 | 3 | GO:0022839 | |
| GeneOntologyMolecularFunction | peptide transmembrane transporter activity | 2.76e-03 | 9 | 179 | 2 | GO:1904680 | |
| GeneOntologyMolecularFunction | deoxyribonucleotide binding | 2.76e-03 | 9 | 179 | 2 | GO:0032552 | |
| GeneOntologyMolecularFunction | macromolecule transmembrane transporter activity | 3.46e-03 | 34 | 179 | 3 | GO:0022884 | |
| GeneOntologyMolecularFunction | P-type calcium transporter activity | 4.17e-03 | 11 | 179 | 2 | GO:0005388 | |
| GeneOntologyMolecularFunction | pyrimidine nucleotide binding | 4.17e-03 | 11 | 179 | 2 | GO:0019103 | |
| GeneOntologyMolecularFunction | protein folding chaperone | 4.20e-03 | 73 | 179 | 4 | GO:0044183 | |
| GeneOntologyMolecularFunction | dynein intermediate chain binding | 4.40e-03 | 37 | 179 | 3 | GO:0045505 | |
| GeneOntologyMolecularFunction | catalytic activity, acting on a nucleic acid | TYW3 POLE POLR2B TUT1 XRCC5 GTDC1 GGT2P GGT1 GGT3P DMC1 MLH3 TYW1B TDRD12 | 5.53e-03 | 645 | 179 | 13 | GO:0140640 |
| GeneOntologyMolecularFunction | unfolded protein binding | 5.59e-03 | 126 | 179 | 5 | GO:0051082 | |
| GeneOntologyMolecularFunction | protein transporter activity | 6.29e-03 | 42 | 179 | 3 | GO:0140318 | |
| GeneOntologyBiologicalProcess | inorganic ion transmembrane transport | CACNA1F CACNA1S ANO2 TMEM94 CFTR NTSR1 HTR3E GRIN2A ANO10 KCNG3 HCN2 CATSPER1 SLC11A1 NALCN SLC15A1 KCNJ1 SCN1A SCN3A ATP6V0A4 AFG3L2 SCN5A SCN7A CACNA1G SEC61A1 ATP2A2 ATP2B4 KCNT1 AP3D1 WNK2 HTT | 3.82e-09 | 1017 | 179 | 30 | GO:0098660 |
| GeneOntologyBiologicalProcess | inorganic cation transmembrane transport | CACNA1F CACNA1S TMEM94 CFTR NTSR1 HTR3E GRIN2A KCNG3 HCN2 CATSPER1 SLC11A1 NALCN SLC15A1 KCNJ1 SCN1A SCN3A ATP6V0A4 AFG3L2 SCN5A SCN7A CACNA1G SEC61A1 ATP2A2 ATP2B4 KCNT1 AP3D1 WNK2 HTT | 7.25e-09 | 922 | 179 | 28 | GO:0098662 |
| GeneOntologyBiologicalProcess | monoatomic ion transmembrane transport | CACNA1F CACNA1S ANO2 TMEM94 WWP1 CFTR NTSR1 HTR3E GRIN2A ANO10 KCNG3 HCN2 CATSPER1 SLC11A1 NALCN SLC15A1 KCNJ1 SCN1A SCN3A ATP6V0A4 AFG3L2 SCN5A SCN7A CACNA1G SEC61A1 ATP2A2 ATP2B4 KCNT1 AP3D1 WNK2 HTT | 8.14e-09 | 1115 | 179 | 31 | GO:0034220 |
| GeneOntologyBiologicalProcess | monoatomic cation transmembrane transport | CACNA1F CACNA1S TMEM94 CFTR NTSR1 GRIN2A ANO10 KCNG3 HCN2 CATSPER1 SLC11A1 NALCN SLC15A1 KCNJ1 SCN1A SCN3A ATP6V0A4 AFG3L2 SCN5A SCN7A CACNA1G SEC61A1 ATP2A2 ATP2B4 KCNT1 AP3D1 WNK2 HTT | 1.15e-08 | 942 | 179 | 28 | GO:0098655 |
| GeneOntologyBiologicalProcess | monoatomic ion transport | CACNA1F CACNA1S ANO2 OSTM1 TMEM94 WWP1 CFTR NTSR1 HTR3E GRIN2A ANO10 KCNG3 HCN2 CATSPER1 SLC11A1 NALCN SLC15A1 KCNJ1 SCN1A SCN3A ATP6V0A4 AFG3L2 SCN5A SCN7A CACNA1G GNAI2 SEC61A1 ATP2A2 ATP2B4 KCNT1 AP3D1 WNK2 HTT | 8.46e-08 | 1374 | 179 | 33 | GO:0006811 |
| GeneOntologyBiologicalProcess | monoatomic cation transport | CACNA1F CACNA1S TMEM94 CFTR NTSR1 GRIN2A ANO10 KCNG3 HCN2 CATSPER1 SLC11A1 NALCN SLC15A1 KCNJ1 SCN1A SCN3A ATP6V0A4 AFG3L2 SCN5A SCN7A CACNA1G GNAI2 SEC61A1 ATP2A2 ATP2B4 KCNT1 AP3D1 WNK2 HTT | 2.41e-07 | 1157 | 179 | 29 | GO:0006812 |
| GeneOntologyBiologicalProcess | metal ion transport | CACNA1F CACNA1S TMEM94 CFTR NTSR1 GRIN2A KCNG3 HCN2 CATSPER1 SLC11A1 NALCN KCNJ1 SCN1A SCN3A AFG3L2 SCN5A SCN7A CACNA1G GNAI2 SEC61A1 ATP2A2 ATP2B4 KCNT1 AP3D1 WNK2 HTT | 5.50e-07 | 1000 | 179 | 26 | GO:0030001 |
| GeneOntologyBiologicalProcess | cytosol to endoplasmic reticulum transport | 6.35e-06 | 5 | 179 | 3 | GO:0046967 | |
| GeneOntologyBiologicalProcess | cardiac muscle cell action potential | 1.07e-05 | 87 | 179 | 7 | GO:0086001 | |
| GeneOntologyBiologicalProcess | membrane depolarization during action potential | 1.41e-05 | 36 | 179 | 5 | GO:0086010 | |
| GeneOntologyBiologicalProcess | sodium ion transmembrane transport | 1.44e-05 | 208 | 179 | 10 | GO:0035725 | |
| GeneOntologyBiologicalProcess | sodium ion transport | CFTR HCN2 NALCN KCNJ1 SCN1A SCN3A SCN5A SCN7A CACNA1G ATP2B4 WNK2 | 2.97e-05 | 275 | 179 | 11 | GO:0006814 |
| GeneOntologyBiologicalProcess | import across plasma membrane | CACNA1F CACNA1S NTSR1 HCN2 SLC15A1 KCNJ1 SCN5A CACNA1G ATP2B4 WNK2 | 3.41e-05 | 230 | 179 | 10 | GO:0098739 |
| GeneOntologyBiologicalProcess | inorganic cation import across plasma membrane | 3.43e-05 | 142 | 179 | 8 | GO:0098659 | |
| GeneOntologyBiologicalProcess | inorganic ion import across plasma membrane | 3.43e-05 | 142 | 179 | 8 | GO:0099587 | |
| GeneOntologyBiologicalProcess | cysteine biosynthetic process | 3.49e-05 | 8 | 179 | 3 | GO:0019344 | |
| GeneOntologyBiologicalProcess | detection of stimulus involved in sensory perception | CACNA1F OR5T1 OR5B2 OR1S2 NTSR1 OR5T2 OR2S2 OR6C68 GRIN2A OR2T11 OR1J2 OR10G7 OR5J2 SCN1A OR10G9 OR4X1 | 5.03e-05 | 582 | 179 | 16 | GO:0050906 |
| GeneOntologyBiologicalProcess | action potential | 6.75e-05 | 201 | 179 | 9 | GO:0001508 | |
| GeneOntologyBiologicalProcess | leukotriene D4 biosynthetic process | 7.37e-05 | 10 | 179 | 3 | GO:1901750 | |
| GeneOntologyBiologicalProcess | peptide modification | 7.37e-05 | 10 | 179 | 3 | GO:0031179 | |
| GeneOntologyBiologicalProcess | membrane depolarization | 9.06e-05 | 121 | 179 | 7 | GO:0051899 | |
| GeneOntologyBiologicalProcess | glutathione catabolic process | 1.01e-04 | 11 | 179 | 3 | GO:0006751 | |
| GeneOntologyBiologicalProcess | regulation of membrane potential | CFTR NTSR1 HTR3E GRIN2A KCNG3 HCN2 NALCN SCN1A SCN3A SCN5A SCN7A MFN2 CACNA1G ATP2A2 KCNT1 | 1.14e-04 | 559 | 179 | 15 | GO:0042391 |
| GeneOntologyBiologicalProcess | leukotriene D4 metabolic process | 1.33e-04 | 12 | 179 | 3 | GO:1901748 | |
| GeneOntologyBiologicalProcess | cardiac muscle cell contraction | 1.60e-04 | 93 | 179 | 6 | GO:0086003 | |
| GeneOntologyBiologicalProcess | calcium ion transmembrane transport | CACNA1F CACNA1S NTSR1 GRIN2A CATSPER1 NALCN AFG3L2 CACNA1G SEC61A1 ATP2A2 ATP2B4 HTT | 1.69e-04 | 392 | 179 | 12 | GO:0070588 |
| GeneOntologyBiologicalProcess | regulation of membrane depolarization | 1.87e-04 | 61 | 179 | 5 | GO:0003254 | |
| GeneOntologyBiologicalProcess | detection of stimulus | CACNA1F OR5T1 OR5B2 OR1S2 NTSR1 OR5T2 OR2S2 OR6C68 GRIN2A OR2T11 OR1J2 OR10G7 OR5J2 SCN1A TLR2 OR10G9 OR4X1 | 1.91e-04 | 722 | 179 | 17 | GO:0051606 |
| GeneOntologyBiologicalProcess | cardiac muscle cell action potential involved in contraction | 2.02e-04 | 62 | 179 | 5 | GO:0086002 | |
| GeneOntologyBiologicalProcess | sensory perception of smell | OR5T1 PDE1C OR5B2 OR1S2 OR5T2 OR2S2 OR6C68 OR2T11 OR1J2 OR10G7 OR5J2 OR10G9 OR4X1 | 2.20e-04 | 465 | 179 | 13 | GO:0007608 |
| GeneOntologyBiologicalProcess | mitochondrial fusion | 2.90e-04 | 37 | 179 | 4 | GO:0008053 | |
| GeneOntologyBiologicalProcess | cysteine metabolic process | 3.31e-04 | 16 | 179 | 3 | GO:0006534 | |
| GeneOntologyBiologicalProcess | cytosolic transport | 3.42e-04 | 150 | 179 | 7 | GO:0016482 | |
| GeneOntologyBiologicalProcess | detection of chemical stimulus involved in sensory perception of smell | OR5T1 OR5B2 OR1S2 OR5T2 OR2S2 OR6C68 OR2T11 OR1J2 OR10G7 OR5J2 OR10G9 OR4X1 | 4.08e-04 | 432 | 179 | 12 | GO:0050911 |
| GeneOntologyBiologicalProcess | leukotriene metabolic process | 4.32e-04 | 41 | 179 | 4 | GO:0006691 | |
| GeneOntologyBiologicalProcess | calcium ion transport | CACNA1F CACNA1S NTSR1 GRIN2A CATSPER1 NALCN AFG3L2 CACNA1G GNAI2 SEC61A1 ATP2A2 ATP2B4 HTT | 5.21e-04 | 509 | 179 | 13 | GO:0006816 |
| GeneOntologyBiologicalProcess | chemical homeostasis | CACNA1F CACNA1S PDE1C ACACA TMEM94 CFTR NTSR1 PTCH1 NR1D1 CYP39A1 SLC11A1 TIAM1 ASL ATP6V0A4 AFG3L2 SCN7A PKHD1 MFN2 ATP2A2 ATP2B4 WNK2 HTT ACOXL | 5.24e-04 | 1249 | 179 | 23 | GO:0048878 |
| GeneOntologyBiologicalProcess | intracellular chemical homeostasis | CACNA1F CACNA1S PDE1C TMEM94 CFTR NTSR1 NR1D1 SLC11A1 TIAM1 ASL ATP6V0A4 AFG3L2 SCN7A PKHD1 MFN2 ATP2A2 ATP2B4 HTT | 5.55e-04 | 866 | 179 | 18 | GO:0055082 |
| GeneOntologyBiologicalProcess | alpha-amino acid biosynthetic process | 5.55e-04 | 77 | 179 | 5 | GO:1901607 | |
| GeneOntologyCellularComponent | monoatomic ion channel complex | CACNA1F CACNA1S ANO2 OSTM1 CFTR HTR3E GRIN2A KCNG3 HCN2 CATSPER1 NALCN KCNJ1 SCN1A SCN3A SCN5A SCN7A CACNA1G | 2.94e-08 | 378 | 179 | 17 | GO:0034702 |
| GeneOntologyCellularComponent | transmembrane transporter complex | CACNA1F CACNA1S ANO2 OSTM1 CFTR HTR3E GRIN2A KCNG3 HCN2 CATSPER1 NALCN KCNJ1 SCN1A SCN3A ATP6V0A4 SCN5A SCN7A CACNA1G ATP2A2 | 1.28e-07 | 523 | 179 | 19 | GO:1902495 |
| GeneOntologyCellularComponent | voltage-gated sodium channel complex | 2.48e-07 | 17 | 179 | 5 | GO:0001518 | |
| GeneOntologyCellularComponent | transporter complex | CACNA1F CACNA1S ANO2 OSTM1 CFTR HTR3E GRIN2A KCNG3 HCN2 CATSPER1 NALCN KCNJ1 SCN1A SCN3A ATP6V0A4 SCN5A SCN7A CACNA1G ATP2A2 | 2.77e-07 | 550 | 179 | 19 | GO:1990351 |
| GeneOntologyCellularComponent | membrane protein complex | CACNA1F CACNA1S ANO2 CHMP6 CLTCL1 OSTM1 CDHR3 CFTR HTR3E GRIN2A KCNG3 HCN2 SEC61A2 CATSPER1 YKT6 NALCN KCNJ1 SCN1A SCN3A ATP6V0A4 TLR2 AFG3L2 SCN5A SCN7A CACNA1G GNAI2 DENND5A AP4M1 SEC61A1 ATP2A2 TAP1 AP3D1 | 1.36e-06 | 1498 | 179 | 32 | GO:0098796 |
| GeneOntologyCellularComponent | sodium channel complex | 4.38e-06 | 29 | 179 | 5 | GO:0034706 | |
| GeneOntologyCellularComponent | cation channel complex | CACNA1F CACNA1S HTR3E KCNG3 HCN2 CATSPER1 SCN1A SCN3A SCN5A SCN7A CACNA1G | 6.06e-06 | 235 | 179 | 11 | GO:0034703 |
| GeneOntologyCellularComponent | somatodendritic compartment | CACNA1F CACNA1S PDE1A PDE1C TMEM50A ADAM21 CFTR NTSR1 GRIN2A ACTN1 PTCH1 HCN2 NR1D1 TENM2 YKT6 TIAM1 FARP1 ASL SCN1A SCN3A VPS13A CACNA1G GNAI2 HSP90AA1 HTT HSP90AB1 | 1.78e-05 | 1228 | 179 | 26 | GO:0036477 |
| GeneOntologyCellularComponent | axonal growth cone | 4.03e-05 | 45 | 179 | 5 | GO:0044295 | |
| GeneOntologyCellularComponent | cell body | CACNA1F PDE1A PDE1C TMEM50A ADAM21 CFTR NTSR1 HCN2 NR1D1 YKT6 TIAM1 ASL SCN1A SCN3A TLR2 VPS13A CACNA1G GNAI2 HSP90AA1 HTT HSP90AB1 | 4.86e-05 | 929 | 179 | 21 | GO:0044297 |
| GeneOntologyCellularComponent | neuronal cell body | CACNA1F PDE1A PDE1C TMEM50A ADAM21 CFTR NTSR1 HCN2 NR1D1 YKT6 TIAM1 ASL SCN1A SCN3A VPS13A CACNA1G HSP90AA1 HTT HSP90AB1 | 1.04e-04 | 835 | 179 | 19 | GO:0043025 |
| GeneOntologyCellularComponent | dendritic growth cone | 1.28e-04 | 12 | 179 | 3 | GO:0044294 | |
| GeneOntologyCellularComponent | sperm flagellum | 5.29e-04 | 214 | 179 | 8 | GO:0036126 | |
| GeneOntologyCellularComponent | dendrite terminus | 6.32e-04 | 20 | 179 | 3 | GO:0044292 | |
| GeneOntologyCellularComponent | voltage-gated calcium channel complex | 6.41e-04 | 46 | 179 | 4 | GO:0005891 | |
| GeneOntologyCellularComponent | cluster of actin-based cell projections | ACTN1 TIAM1 SLC15A1 MUC17 ATP6V0A4 ANKRD24 HSP90AA1 HSP90AB1 | 6.93e-04 | 223 | 179 | 8 | GO:0098862 |
| GeneOntologyCellularComponent | Sec61 translocon complex | 7.17e-04 | 5 | 179 | 2 | GO:0005784 | |
| GeneOntologyCellularComponent | phagocytic vesicle membrane | 7.37e-04 | 83 | 179 | 5 | GO:0030670 | |
| GeneOntologyCellularComponent | sperm plasma membrane | 8.43e-04 | 22 | 179 | 3 | GO:0097524 | |
| GeneOntologyCellularComponent | extrinsic component of postsynaptic membrane | 8.43e-04 | 22 | 179 | 3 | GO:0098890 | |
| GeneOntologyCellularComponent | kinetochore microtubule | 8.43e-04 | 22 | 179 | 3 | GO:0005828 | |
| GeneOntologyCellularComponent | 9+2 motile cilium | 1.06e-03 | 238 | 179 | 8 | GO:0097729 | |
| GeneOntologyCellularComponent | translocon complex | 1.07e-03 | 6 | 179 | 2 | GO:0071256 | |
| GeneOntologyCellularComponent | ficolin-1-rich granule | 1.10e-03 | 185 | 179 | 7 | GO:0101002 | |
| GeneOntologyCellularComponent | dendrite | CACNA1S CFTR NTSR1 GRIN2A ACTN1 PTCH1 HCN2 NR1D1 TENM2 YKT6 TIAM1 FARP1 CACNA1G GNAI2 HSP90AA1 HTT HSP90AB1 | 1.15e-03 | 858 | 179 | 17 | GO:0030425 |
| GeneOntologyCellularComponent | dendritic spine | 1.18e-03 | 242 | 179 | 8 | GO:0043197 | |
| GeneOntologyCellularComponent | extrinsic component of plasma membrane | 1.18e-03 | 137 | 179 | 6 | GO:0019897 | |
| GeneOntologyCellularComponent | dendritic tree | CACNA1S CFTR NTSR1 GRIN2A ACTN1 PTCH1 HCN2 NR1D1 TENM2 YKT6 TIAM1 FARP1 CACNA1G GNAI2 HSP90AA1 HTT HSP90AB1 | 1.18e-03 | 860 | 179 | 17 | GO:0097447 |
| GeneOntologyCellularComponent | cell-cell contact zone | 1.29e-03 | 94 | 179 | 5 | GO:0044291 | |
| GeneOntologyCellularComponent | neuron spine | 1.34e-03 | 247 | 179 | 8 | GO:0044309 | |
| GeneOntologyCellularComponent | axon | ADAM21 CDHR3 NTSR1 CLASP2 GRIN2A PTCH1 HCN2 TENM2 TIAM1 SCN1A SCN3A SCN5A AP3D1 SLC38A8 HSP90AA1 HTT HSP90AB1 | 1.73e-03 | 891 | 179 | 17 | GO:0030424 |
| GeneOntologyCellularComponent | brush border | 2.00e-03 | 152 | 179 | 6 | GO:0005903 | |
| GeneOntologyCellularComponent | secretory granule lumen | DOCK2 APAF1 ACTN1 HUWE1 XRCC5 ITIH4 VPS13A HSP90AA1 HSP90AB1 | 2.01e-03 | 325 | 179 | 9 | GO:0034774 |
| GeneOntologyCellularComponent | cytoplasmic vesicle lumen | DOCK2 APAF1 ACTN1 HUWE1 XRCC5 ITIH4 VPS13A HSP90AA1 HSP90AB1 | 2.22e-03 | 330 | 179 | 9 | GO:0060205 |
| GeneOntologyCellularComponent | vesicle lumen | DOCK2 APAF1 ACTN1 HUWE1 XRCC5 ITIH4 VPS13A HSP90AA1 HSP90AB1 | 2.32e-03 | 332 | 179 | 9 | GO:0031983 |
| GeneOntologyCellularComponent | endocytic vesicle membrane | 2.39e-03 | 212 | 179 | 7 | GO:0030666 | |
| GeneOntologyCellularComponent | intercalated disc | 2.76e-03 | 68 | 179 | 4 | GO:0014704 | |
| GeneOntologyCellularComponent | plasma membrane protein complex | CACNA1F CACNA1S CDHR3 HTR3E GRIN2A KCNG3 HCN2 CATSPER1 SCN1A SCN3A TLR2 SCN5A SCN7A CACNA1G GNAI2 | 3.16e-03 | 785 | 179 | 15 | GO:0098797 |
| GeneOntologyCellularComponent | extrinsic component of synaptic membrane | 3.30e-03 | 35 | 179 | 3 | GO:0099243 | |
| GeneOntologyCellularComponent | chromosomal region | KNTC1 CHMP6 POLR2B CLASP2 XRCC5 STN1 DMC1 NCAPD2 PKHD1 NUP160 | 3.49e-03 | 421 | 179 | 10 | GO:0098687 |
| GeneOntologyCellularComponent | calcium channel complex | 3.57e-03 | 73 | 179 | 4 | GO:0034704 | |
| GeneOntologyCellularComponent | sperm head plasma membrane | 3.81e-03 | 11 | 179 | 2 | GO:1990913 | |
| GeneOntologyCellularComponent | cell projection membrane | NCKAP1 CLASP2 GRIN2A PTCH1 HCN2 TIAM1 MUC17 ATP6V0A4 HSP90AA1 HSP90AB1 | 4.12e-03 | 431 | 179 | 10 | GO:0031253 |
| GeneOntologyCellularComponent | distal axon | CDHR3 NTSR1 CLASP2 GRIN2A PTCH1 TENM2 TIAM1 AP3D1 HSP90AA1 HSP90AB1 | 4.39e-03 | 435 | 179 | 10 | GO:0150034 |
| GeneOntologyCellularComponent | outer dynein arm | 4.55e-03 | 12 | 179 | 2 | GO:0036157 | |
| GeneOntologyCellularComponent | SCAR complex | 4.55e-03 | 12 | 179 | 2 | GO:0031209 | |
| GeneOntologyCellularComponent | T-tubule | 4.74e-03 | 79 | 179 | 4 | GO:0030315 | |
| MousePheno | abnormal circulating glutathione level | 8.88e-06 | 5 | 136 | 3 | MP:0030652 | |
| MousePheno | increased circulating glutathione level | 8.88e-06 | 5 | 136 | 3 | MP:0030653 | |
| MousePheno | glutathionuria | 8.88e-06 | 5 | 136 | 3 | MP:0013730 | |
| MousePheno | increased glutathione level | 8.88e-06 | 5 | 136 | 3 | MP:0012606 | |
| MousePheno | decreased circulating cysteine level | 3.06e-05 | 7 | 136 | 3 | MP:0030626 | |
| MousePheno | decreased cysteine level | 4.87e-05 | 8 | 136 | 3 | MP:0030623 | |
| MousePheno | epididymis hypoplasia | 4.87e-05 | 8 | 136 | 3 | MP:0004932 | |
| MousePheno | nervous | 7.25e-05 | 9 | 136 | 3 | MP:0008912 | |
| MousePheno | abnormal spike wave discharge | 7.83e-05 | 24 | 136 | 4 | MP:0008840 | |
| MousePheno | bile duct epithelium hyperplasia | 9.40e-05 | 2 | 136 | 2 | MP:0014233 | |
| MousePheno | failure of copulatory plug deposition | 1.03e-04 | 10 | 136 | 3 | MP:0030983 | |
| MousePheno | seminal vesicle hypoplasia | 1.03e-04 | 10 | 136 | 3 | MP:0005148 | |
| MousePheno | ovary hypoplasia | 1.03e-04 | 10 | 136 | 3 | MP:0005158 | |
| MousePheno | abnormal cell motility | SEMA3C NCKAP1 TMEM94 CFTR APAF1 XPO4 CLASP2 PLXNB2 GGT2P GGT1 GGT3P FSIP2 CATSPER1 DNAH17 TLR2 VPS13A GNAI2 ATP2A2 DNAH8 ATP2B4 NCKAP1L | 1.25e-04 | 885 | 136 | 21 | MP:0020846 |
| MousePheno | acanthocytosis | 1.40e-04 | 11 | 136 | 3 | MP:0010177 | |
| MousePheno | abnormal circulating cysteine level | 1.40e-04 | 11 | 136 | 3 | MP:0030624 | |
| MousePheno | absent tertiary ovarian follicles | 1.40e-04 | 11 | 136 | 3 | MP:0011130 | |
| MousePheno | impaired ability to fire action potentials | 2.40e-04 | 13 | 136 | 3 | MP:0002578 | |
| MousePheno | abnormal cysteine level | 2.40e-04 | 13 | 136 | 3 | MP:0030621 | |
| MousePheno | decreased glutathione level | 2.40e-04 | 13 | 136 | 3 | MP:0012604 | |
| MousePheno | abnormal glutathione level | 2.40e-04 | 13 | 136 | 3 | MP:0012603 | |
| MousePheno | abnormal channel response | 2.82e-04 | 33 | 136 | 4 | MP:0003484 | |
| MousePheno | priapism | 3.03e-04 | 14 | 136 | 3 | MP:0003415 | |
| MousePheno | hypoactivity | DOCK3 COL19A1 DSG1 WWP1 POLR2B RABGAP1 GRIN2A XRCC5 HCN2 GGT2P GGT1 GGT3P ZNF605 TIAM1 TYW1B ASL SCN3A VPS13A CACNA1G ATP2A2 KCNT1 HTT | 3.44e-04 | 1023 | 136 | 22 | MP:0031392 |
| MousePheno | absence seizures | 3.55e-04 | 35 | 136 | 4 | MP:0003216 | |
| MousePheno | increased alimentary system tumor incidence | 4.19e-04 | 65 | 136 | 5 | MP:0010292 | |
| MousePheno | abnormal copulatory plug deposition | 4.60e-04 | 16 | 136 | 3 | MP:0030982 | |
| MousePheno | decreased spleen red pulp amount | 4.60e-04 | 16 | 136 | 3 | MP:0008477 | |
| MousePheno | premature death | USP18 OSTM1 POLE CFTR APAF1 PTCH1 HCN2 GGT2P GGT1 GGT3P MTUS1 ASL SCN1A ATP6V0A4 TLR2 SCN5A PKHD1 GNAI2 ATP2A2 KCNT1 HTT SON | 4.98e-04 | 1051 | 136 | 22 | MP:0002083 |
| Domain | Channel_four-helix_dom | CACNA1F CACNA1S KCNG3 CATSPER1 NALCN SCN1A SCN3A SCN5A SCN7A CACNA1G | 1.12e-10 | 57 | 174 | 10 | IPR027359 |
| Domain | - | CACNA1F CACNA1S KCNG3 CATSPER1 NALCN SCN1A SCN3A SCN5A SCN7A CACNA1G | 1.12e-10 | 57 | 174 | 10 | 1.20.120.350 |
| Domain | Ion_trans_dom | CACNA1F CACNA1S KCNG3 HCN2 CATSPER1 NALCN SCN1A SCN3A SCN5A SCN7A CACNA1G | 9.38e-09 | 114 | 174 | 11 | IPR005821 |
| Domain | Ion_trans | CACNA1F CACNA1S KCNG3 HCN2 CATSPER1 NALCN SCN1A SCN3A SCN5A SCN7A CACNA1G | 9.38e-09 | 114 | 174 | 11 | PF00520 |
| Domain | Na_channel_asu | 1.46e-06 | 10 | 174 | 4 | IPR001696 | |
| Domain | Na_trans_assoc | 1.46e-06 | 10 | 174 | 4 | IPR010526 | |
| Domain | Na_trans_assoc | 1.46e-06 | 10 | 174 | 4 | PF06512 | |
| Domain | ARM-type_fold | DOCK2 DOCK3 CLTCL1 XPO4 CLASP2 HUWE1 TRRAP MROH8 ELMO2 NCAPD2 MROH7 STKLD1 AP3D1 HTT | 3.69e-06 | 339 | 174 | 14 | IPR016024 |
| Domain | Na_trans_cytopl | 1.56e-05 | 6 | 174 | 3 | PF11933 | |
| Domain | Na_trans_cytopl | 1.56e-05 | 6 | 174 | 3 | IPR024583 | |
| Domain | ARM-like | DOCK2 XPO4 CLASP2 HUWE1 TRRAP ELMO2 NCAPD2 MROH7 STKLD1 AP3D1 HTT | 4.73e-05 | 270 | 174 | 11 | IPR011989 |
| Domain | SecY_su_dom | 8.63e-05 | 2 | 174 | 2 | IPR023201 | |
| Domain | Nck-associated_protein-1 | 8.63e-05 | 2 | 174 | 2 | IPR019137 | |
| Domain | SECY_1 | 8.63e-05 | 2 | 174 | 2 | PS00755 | |
| Domain | SECY_2 | 8.63e-05 | 2 | 174 | 2 | PS00756 | |
| Domain | - | 8.63e-05 | 2 | 174 | 2 | 1.10.3370.10 | |
| Domain | Translocon_Sec61/SecY_plug_dom | 8.63e-05 | 2 | 174 | 2 | IPR019561 | |
| Domain | SecY_CS | 8.63e-05 | 2 | 174 | 2 | IPR030659 | |
| Domain | Plug_translocon | 8.63e-05 | 2 | 174 | 2 | PF10559 | |
| Domain | SecY | 8.63e-05 | 2 | 174 | 2 | PF00344 | |
| Domain | Nckap1 | 8.63e-05 | 2 | 174 | 2 | PF09735 | |
| Domain | SecY/SEC61-alpha | 8.63e-05 | 2 | 174 | 2 | IPR002208 | |
| Domain | VDCCAlpha1 | 9.09e-05 | 10 | 174 | 3 | IPR002077 | |
| Domain | Heat_shock_protein_90_CS | 2.57e-04 | 3 | 174 | 2 | IPR019805 | |
| Domain | PDEase_N | 2.57e-04 | 3 | 174 | 2 | IPR013706 | |
| Domain | PDEase_I_N | 2.57e-04 | 3 | 174 | 2 | PF08499 | |
| Domain | Olfact_rcpt | OR5T1 OR5B2 OR1S2 OR5T2 OR2S2 OR6C68 OR2T11 OR1J2 OR10G7 OR5J2 OR10G9 OR4X1 | 3.26e-04 | 393 | 174 | 12 | IPR000725 |
| Domain | ATPase_P-typ_TM_dom | 4.07e-04 | 16 | 174 | 3 | IPR023298 | |
| Domain | - | 4.07e-04 | 16 | 174 | 3 | 1.20.1110.10 | |
| Domain | ATPase_P-typ_cation-transptr_C | 4.91e-04 | 17 | 174 | 3 | IPR006068 | |
| Domain | Cation_ATPase_C | 4.91e-04 | 17 | 174 | 3 | PF00689 | |
| Domain | Hsp90_fam | 5.11e-04 | 4 | 174 | 2 | IPR001404 | |
| Domain | Hsp90_N | 5.11e-04 | 4 | 174 | 2 | IPR020575 | |
| Domain | DNA_repair_Rad51/TF_NusA_a-hlx | 5.11e-04 | 4 | 174 | 2 | IPR010995 | |
| Domain | HSP90 | 5.11e-04 | 4 | 174 | 2 | PF00183 | |
| Domain | VDCC_L_a1su | 5.11e-04 | 4 | 174 | 2 | IPR005446 | |
| Domain | HSP90 | 5.11e-04 | 4 | 174 | 2 | PS00298 | |
| Domain | HATPase_c | 5.85e-04 | 18 | 174 | 3 | SM00387 | |
| Domain | HATPase_c | 6.90e-04 | 19 | 174 | 3 | PF02518 | |
| Domain | - | 8.06e-04 | 20 | 174 | 3 | 3.30.565.10 | |
| Domain | DOCK_N | 8.47e-04 | 5 | 174 | 2 | PF16172 | |
| Domain | DOCK_N | 8.47e-04 | 5 | 174 | 2 | IPR032376 | |
| Domain | HATPase_C | 9.34e-04 | 21 | 174 | 3 | IPR003594 | |
| Domain | - | 1.15e-03 | 222 | 174 | 8 | 1.25.10.10 | |
| Domain | ITI_HC_C | 1.26e-03 | 6 | 174 | 2 | IPR010600 | |
| Domain | ITI_HC_C | 1.26e-03 | 6 | 174 | 2 | PF06668 | |
| Domain | EF-hand-dom_pair | 1.52e-03 | 287 | 174 | 9 | IPR011992 | |
| Domain | GGT_peptidase | 1.76e-03 | 7 | 174 | 2 | IPR000101 | |
| Domain | G_glu_transpept | 1.76e-03 | 7 | 174 | 2 | PF01019 | |
| Domain | Ca_chan_IQ | 1.76e-03 | 7 | 174 | 2 | SM01062 | |
| Domain | Ca_chan_IQ | 1.76e-03 | 7 | 174 | 2 | PF08763 | |
| Domain | VDCC_a1su_IQ | 1.76e-03 | 7 | 174 | 2 | IPR014873 | |
| Domain | G_GLU_TRANSPEPTIDASE | 1.76e-03 | 7 | 174 | 2 | PS00462 | |
| Domain | GPHH | 1.76e-03 | 7 | 174 | 2 | PF16905 | |
| Domain | GPHH_dom | 1.76e-03 | 7 | 174 | 2 | IPR031649 | |
| Domain | AAA | 2.32e-03 | 144 | 174 | 6 | SM00382 | |
| Domain | AAA+_ATPase | 2.32e-03 | 144 | 174 | 6 | IPR003593 | |
| Domain | VIT | 2.33e-03 | 8 | 174 | 2 | PF08487 | |
| Domain | VIT | 2.33e-03 | 8 | 174 | 2 | SM00609 | |
| Pathway | REACTOME_RHO_GTPASE_CYCLE | DOCK2 DOCK3 NCKAP1 SWAP70 DSG1 CFTR ARHGAP30 ACTN1 FAM83B YKT6 TIAM1 ELMO2 FARP1 HSP90AA1 HSP90AB1 NCKAP1L | 1.10e-05 | 450 | 141 | 16 | M27078 |
| Pathway | REACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3 | DOCK2 DOCK3 KNTC1 NCKAP1 SWAP70 DSG1 CFTR ARHGAP30 CLASP2 ACTN1 FAM83B YKT6 TIAM1 ELMO2 FARP1 MFN2 NUP160 HSP90AA1 HSP90AB1 NCKAP1L | 3.16e-05 | 720 | 141 | 20 | M41838 |
| Pathway | KEGG_MEDICUS_REFERENCE_VGCC_CA2_APOPTOTIC_PATHWAY | 7.33e-05 | 23 | 141 | 4 | M47666 | |
| Pathway | KEGG_CALCIUM_SIGNALING_PATHWAY | CACNA1F CACNA1S PDE1A PDE1C NTSR1 GRIN2A CACNA1G ATP2A2 ATP2B4 | 7.47e-05 | 178 | 141 | 9 | M2890 |
| Pathway | REACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3 | DOCK2 KNTC1 NCKAP1 SWAP70 DSG1 CFTR ARHGAP30 CLASP2 ACTN1 FAM83B YKT6 ELMO2 FARP1 MFN2 NUP160 HSP90AA1 HSP90AB1 NCKAP1L | 8.30e-05 | 649 | 141 | 18 | MM15690 |
| Pathway | REACTOME_ION_CHANNEL_TRANSPORT | 9.25e-05 | 183 | 141 | 9 | M997 | |
| Pathway | REACTOME_RAC1_GTPASE_CYCLE | 9.64e-05 | 184 | 141 | 9 | M41809 | |
| Pathway | REACTOME_RHO_GTPASE_CYCLE | DOCK2 NCKAP1 SWAP70 DSG1 CFTR ARHGAP30 ACTN1 FAM83B YKT6 ELMO2 FARP1 HSP90AA1 HSP90AB1 NCKAP1L | 1.29e-04 | 439 | 141 | 14 | MM15595 |
| Pathway | REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS | 2.45e-04 | 31 | 141 | 4 | M877 | |
| Pathway | REACTOME_RAC2_GTPASE_CYCLE | 2.49e-04 | 88 | 141 | 6 | M41810 | |
| Pathway | REACTOME_PHASE_0_RAPID_DEPOLARISATION | 2.77e-04 | 32 | 141 | 4 | M27455 | |
| Pathway | REACTOME_OLFACTORY_SIGNALING_PATHWAY | ANO2 OR5T1 OR5B2 OR1S2 OR5T2 OR2S2 OR6C68 OR2T11 OR1J2 OR10G7 OR5J2 OR10G9 OR4X1 | 2.82e-04 | 417 | 141 | 13 | M4072 |
| Pathway | REACTOME_ION_CHANNEL_TRANSPORT | 3.89e-04 | 176 | 141 | 8 | MM15718 | |
| Pubmed | Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development. | CACNA1F CACNA1S HCN2 KCNJ1 SCN1A SCN3A SCN5A SCN7A CACNA1G ATP2A2 | 3.21e-09 | 139 | 180 | 10 | 16985003 |
| Pubmed | A dual-activity topoisomerase complex regulates mRNA translation and turnover. | DOCK3 CHMP6 CLTCL1 ACACA TMEM94 MTHFD1L POLE WWP1 NTSR1 CLASP2 HUWE1 PTCH1 PLXNB2 TRRAP FAT1 PCNX4 SCN5A NCAPD2 MFN2 DENND5A AP3D1 WNK2 HTT | 1.63e-08 | 1105 | 180 | 23 | 35748872 |
| Pubmed | ACACA NCKAP1 POLR2B HNRNPM CLASP2 ACTN1 HUWE1 XRCC5 NUP205 YKT6 NCAPD2 ATP2A2 AP3D1 NUP160 HSP90AA1 SON HSP90AB1 | 4.33e-08 | 638 | 180 | 17 | 33239621 | |
| Pubmed | Different gamma-glutamyl transpeptidase mRNAs are expressed in human liver and kidney. | 1.36e-07 | 3 | 180 | 3 | 2573352 | |
| Pubmed | MIA3 NCKAP1 HNRNPM CLASP2 GRIN2A HUWE1 XRCC5 HCN2 TENM2 ITIH4 KCNJ1 FARP1 KIAA1217 MFN2 NEURL4 ATP2B4 KCNT1 WNK2 HSP90AA1 HSP90AB1 | 1.56e-07 | 963 | 180 | 20 | 28671696 | |
| Pubmed | Physiological and pathophysiological characteristics of ataxin-3 isoforms. | ACACA NCKAP1 DSG1 HNRNPM ACTN1 HUWE1 XRCC5 HSP90AB2P SEC61A1 HSP90AA1 HSP90AB1 | 2.78e-07 | 281 | 180 | 11 | 30455355 |
| Pubmed | SEMA3C MIA3 ACACA NCKAP1 SWAP70 MTHFD1L POLR2B OSGEP XRCC5 PLXNB2 TRRAP FAT1 AFG3L2 MFN2 CDYL GNAI2 SEC61A1 ATP2A2 TAP1 AP3D1 NUP160 HSP90AA1 HSP90AB1 | 2.87e-07 | 1297 | 180 | 23 | 33545068 | |
| Pubmed | MTHFD1L POLR2B FASTKD5 NUP205 AFG3L2 NCAPD2 MFN2 ATP2A2 HSP90AA1 HSP90AB1 | 4.96e-07 | 237 | 180 | 10 | 29564676 | |
| Pubmed | REV-ERBα influences the stability and nuclear localization of the glucocorticoid receptor. | 5.43e-07 | 4 | 180 | 3 | 27686098 | |
| Pubmed | COL6A3 HNRNPM TRRAP SCN1A SCN5A DNAH8 NUP160 HSP90AA1 HSP90AB1 | 6.27e-07 | 187 | 180 | 9 | 26460568 | |
| Pubmed | Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells. | ACACA NCKAP1 SWAP70 DSG1 MTHFD1L HNRNPM RABGAP1 ACTN1 ANO10 HUWE1 XRCC5 PLXNB2 NUP205 YKT6 MTUS1 NCAPD2 GNAI2 SEC61A1 ATP2A2 NUP160 HSP90AA1 SON HSP90AB1 | 7.11e-07 | 1367 | 180 | 23 | 32687490 |
| Pubmed | MIA3 MTHFD1L POLE POLR2B APAF1 HNRNPM FASTKD5 CLASP2 TRAPPC8 XRCC5 PLXNB2 FAM83B SEC61A2 YKT6 TIAM1 FARP1 AFG3L2 VPS13A SEC61A1 ATP2A2 NEURL4 ATP2B4 AP3D1 FAM177A1 | 8.32e-07 | 1487 | 180 | 24 | 33957083 | |
| Pubmed | Hsp90 cochaperone Aha1 downregulation rescues misfolding of CFTR in cystic fibrosis. | CLTCL1 CFTR SEC61A2 TIAM1 GNAI2 SEC61A1 ATP2A2 HSP90AA1 HSP90AB1 | 8.90e-07 | 195 | 180 | 9 | 17110338 |
| Pubmed | KAP1 facilitates reinstatement of heterochromatin after DNA replication. | ACACA NCKAP1 MTHFD1L POLE POLR2B APAF1 HNRNPM HUWE1 OSGEP TRRAP NUP205 SEC61A1 DNAH8 AP3D1 NUP160 SON | 9.09e-07 | 704 | 180 | 16 | 29955894 |
| Pubmed | LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy. | 1.19e-06 | 202 | 180 | 9 | 33005030 | |
| Pubmed | The HSP90 family of genes in the human genome: insights into their divergence and evolution. | 1.20e-06 | 16 | 180 | 4 | 16269234 | |
| Pubmed | 1.35e-06 | 5 | 180 | 3 | 23615310 | ||
| Pubmed | 1.35e-06 | 5 | 180 | 3 | 11003618 | ||
| Pubmed | 1.35e-06 | 5 | 180 | 3 | 10392451 | ||
| Pubmed | 1.35e-06 | 5 | 180 | 3 | 19850887 | ||
| Pubmed | Reversible skeletal abnormalities in gamma-glutamyl transpeptidase-deficient mice. | 1.35e-06 | 5 | 180 | 3 | 12810527 | |
| Pubmed | Growth retardation and cysteine deficiency in gamma-glutamyl transpeptidase-deficient mice. | 1.35e-06 | 5 | 180 | 3 | 8755578 | |
| Pubmed | Reproductive defects in gamma-glutamyl transpeptidase-deficient mice. | 1.35e-06 | 5 | 180 | 3 | 11089562 | |
| Pubmed | 1.35e-06 | 5 | 180 | 3 | 26977590 | ||
| Pubmed | Gamma-glutamyl transferase deficiency results in lung oxidant stress in normoxia. | 1.35e-06 | 5 | 180 | 3 | 12225953 | |
| Pubmed | 1.35e-06 | 5 | 180 | 3 | 7775425 | ||
| Pubmed | 1.35e-06 | 5 | 180 | 3 | 9139708 | ||
| Pubmed | 1.35e-06 | 5 | 180 | 3 | 20622017 | ||
| Pubmed | Accelerated methylmercury elimination in gamma-glutamyl transpeptidase-deficient mice. | 1.35e-06 | 5 | 180 | 3 | 9546365 | |
| Pubmed | 1.35e-06 | 5 | 180 | 3 | 7485380 | ||
| Pubmed | Accumulation of DNA damage in the organs of mice deficient in gamma-glutamyltranspeptidase. | 1.35e-06 | 5 | 180 | 3 | 10751614 | |
| Pubmed | Type VI RNA is the major gamma-glutamyl transpeptidase RNA in the mouse small intestine. | 1.35e-06 | 5 | 180 | 3 | 7523374 | |
| Pubmed | Cardio-reno-hepatic interactions in acute heart failure: the role of γ-glutamyl transferase. | 1.35e-06 | 5 | 180 | 3 | 24698228 | |
| Pubmed | 1.35e-06 | 5 | 180 | 3 | 10474818 | ||
| Pubmed | Lung lining fluid glutathione attenuates IL-13-induced asthma. | 1.35e-06 | 5 | 180 | 3 | 18063838 | |
| Pubmed | 1.35e-06 | 5 | 180 | 3 | 10940879 | ||
| Pubmed | Cataract development in gamma-glutamyl transpeptidase-deficient mice. | 1.35e-06 | 5 | 180 | 3 | 11095909 | |
| Pubmed | 1.35e-06 | 5 | 180 | 3 | 7641802 | ||
| Pubmed | 1.35e-06 | 5 | 180 | 3 | 9627710 | ||
| Pubmed | 1.35e-06 | 5 | 180 | 3 | 12453183 | ||
| Pubmed | 1.35e-06 | 5 | 180 | 3 | 19805107 | ||
| Pubmed | 1.35e-06 | 5 | 180 | 3 | 2891746 | ||
| Pubmed | 1.35e-06 | 5 | 180 | 3 | 28660214 | ||
| Pubmed | Bleomycin-induced pulmonary fibrosis is attenuated in gamma-glutamyl transpeptidase-deficient mice. | 1.35e-06 | 5 | 180 | 3 | 12468440 | |
| Pubmed | Cloning of cDNA and genomic structure of the mouse gamma-glutamyl transpeptidase-encoding gene. | 1.35e-06 | 5 | 180 | 3 | 8566783 | |
| Pubmed | 1.35e-06 | 5 | 180 | 3 | 30591459 | ||
| Pubmed | 1.35e-06 | 5 | 180 | 3 | 11795900 | ||
| Pubmed | Inhibiting lung lining fluid glutathione metabolism with GGsTop as a novel treatment for asthma. | 1.35e-06 | 5 | 180 | 3 | 25132819 | |
| Pubmed | Characterization of the dwg mutations: dwg and dwg(Bayer) are new mutant alleles of the Ggt1 gene. | 1.35e-06 | 5 | 180 | 3 | 19760322 | |
| Pubmed | A high-throughput approach for measuring temporal changes in the interactome. | KNTC1 CACNA1S ACACA NCKAP1 SWAP70 POLR2B HNRNPM TUT1 RABGAP1 ACTN1 HUWE1 OSGEP XRCC5 NUP205 ASL NCAPD2 GNAI2 HSP90AB2P AP3D1 NUP160 HSP90AA1 HTT HSP90AB1 | 2.04e-06 | 1455 | 180 | 23 | 22863883 |
| Pubmed | DOCK3 MIA3 ACACA NCKAP1 DSG1 HNRNPM RABGAP1 GRIN2A HUWE1 TENM2 YKT6 FARP1 SCN1A KIAA1217 AFG3L2 ATP2A2 WNK2 FAM177A1 HSP90AA1 HSP90AB1 | 2.10e-06 | 1139 | 180 | 20 | 36417873 | |
| Pubmed | Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function. | ACACA NCKAP1 DSG1 MTHFD1L POLE POLR2B HNRNPM ACTN1 HUWE1 XRCC5 TRRAP NUP205 AFG3L2 NCAPD2 GNAI2 HSP90AB2P ATP2A2 AP3D1 NUP160 HSP90AA1 SON HSP90AB1 | 2.20e-06 | 1353 | 180 | 22 | 29467282 |
| Pubmed | The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation. | ZBTB17 POLE POLR2B HNRNPM HIC2 ACTN1 HUWE1 XRCC5 NUP205 FARP1 NUP160 HSP90AA1 SON HSP90AB1 | 2.38e-06 | 583 | 180 | 14 | 29844126 |
| Pubmed | The human cytoplasmic dynein interactome reveals novel activators of motility. | MIA3 ACACA NCKAP1 MTHFD1L POLR2B OSGEP FHIP2A FAM83B NUP205 MTUS1 ELMO2 FARP1 KIAA1217 AP4M1 NEURL4 HSP90AA1 HSP90AB1 | 2.44e-06 | 853 | 180 | 17 | 28718761 |
| Pubmed | 2.70e-06 | 6 | 180 | 3 | 14634009 | ||
| Pubmed | Six mRNAs with different 5' ends are encoded by a single gamma-glutamyltransferase gene in mouse. | 2.70e-06 | 6 | 180 | 3 | 8101000 | |
| Pubmed | Mapping of human gamma-glutamyl transpeptidase genes on chromosome 22 and other human autosomes. | 2.70e-06 | 6 | 180 | 3 | 8104871 | |
| Pubmed | 2.70e-06 | 6 | 180 | 3 | 11463821 | ||
| Pubmed | 2.70e-06 | 6 | 180 | 3 | 25326709 | ||
| Pubmed | 2.70e-06 | 6 | 180 | 3 | 12163373 | ||
| Pubmed | 2.70e-06 | 6 | 180 | 3 | 22242126 | ||
| Pubmed | 2.70e-06 | 6 | 180 | 3 | 17363454 | ||
| Pubmed | 2.70e-06 | 6 | 180 | 3 | 8663190 | ||
| Pubmed | ACACA POLR2B RABGAP1 ACTN1 HUWE1 NUP205 HSP90AA1 HTT SON HSP90AB1 | 2.87e-06 | 288 | 180 | 10 | 23383273 | |
| Pubmed | DOCK2 MIA3 CHMP6 CLTCL1 MTHFD1L HNRNPM CLASP2 ANO10 HUWE1 XRCC5 NUP205 INTS2 NCAPD2 GNAI2 TAP1 ATP2B4 AP3D1 HSP90AA1 HSP90AB1 NCKAP1L | 3.07e-06 | 1168 | 180 | 20 | 19946888 | |
| Pubmed | Transcriptional profiling and therapeutic targeting of oxidative stress in neuroinflammation. | 4.70e-06 | 7 | 180 | 3 | 32284594 | |
| Pubmed | 4.70e-06 | 7 | 180 | 3 | 36685533 | ||
| Pubmed | 4.70e-06 | 7 | 180 | 3 | 27775020 | ||
| Pubmed | 4.70e-06 | 7 | 180 | 3 | 12900400 | ||
| Pubmed | Defective epidermal growth factor gene expression in mice with polycystic kidney disease. | 4.70e-06 | 7 | 180 | 3 | 1968405 | |
| Pubmed | The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery. | MIA3 NCKAP1 DSG1 HNRNPM FASTKD5 ACTN1 ANO10 XRCC5 PLXNB2 NUP205 INTS2 AFG3L2 NCAPD2 MFN2 SEC61A1 ATP2A2 TAP1 AP3D1 NUP160 HSP90AB1 | 4.76e-06 | 1203 | 180 | 20 | 29180619 |
| Pubmed | 6.31e-06 | 87 | 180 | 6 | 12465718 | ||
| Pubmed | Identifying biological pathways that underlie primordial short stature using network analysis. | CHMP6 DSG1 POLR2B ACTN1 HUWE1 XRCC5 PLXNB2 TRRAP FAM83B NUP205 AFG3L2 GNAI2 ATP2A2 TAP1 NEURL4 NUP160 SON HSP90AB1 | 6.91e-06 | 1024 | 180 | 18 | 24711643 |
| Pubmed | 7.49e-06 | 8 | 180 | 3 | 28330839 | ||
| Pubmed | 7.49e-06 | 8 | 180 | 3 | 9023306 | ||
| Pubmed | E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins. | CACNA1F ACACA OR5B2 TOPAZ1 HNRNPM HIC2 HUWE1 XRCC5 NUP205 MROH8 SCN3A TBC1D14 VPS13A PKHD1 HSP90AB1 | 7.49e-06 | 736 | 180 | 15 | 29676528 |
| Pubmed | C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains. | ACACA DSG1 MTHFD1L POLE POLR2B HNRNPM FASTKD5 HUWE1 OSGEP XRCC5 NUP205 SEC61A2 AFG3L2 MFN2 HSP90AB2P SEC61A1 ATP2A2 NUP160 HSP90AA1 HSP90AB1 | 9.06e-06 | 1257 | 180 | 20 | 37317656 |
| Pubmed | SEMA3C HNRNPM XPO4 FASTKD5 HUWE1 INTS2 ELMO2 NCAPD2 VPS13A SEC61A1 ATP2A2 NUP160 HSP90AA1 HSP90AB1 | 9.27e-06 | 657 | 180 | 14 | 36180527 | |
| Pubmed | Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis. | KNTC1 MIA3 CLTCL1 NCKAP1 SWAP70 RABGAP1 ACTN1 XRCC5 KIAA1217 NCAPD2 HSP90AB2P ATP2B4 AP3D1 HSP90AA1 HSP90AA2P HSP90AB1 | 9.51e-06 | 847 | 180 | 16 | 35235311 |
| Pubmed | ACACA DSG1 CFTR HNRNPM ACTN1 OSGEP XRCC5 SEC61A1 ATP2A2 AP3D1 HSP90AA1 HSP90AB1 | 1.01e-05 | 488 | 180 | 12 | 31324722 | |
| Pubmed | A High-Density Human Mitochondrial Proximity Interaction Network. | MIA3 OSTM1 MTHFD1L POLE POLR2B FASTKD5 RABGAP1 HUWE1 XRCC5 PLXNB2 FAM83B SEC61A2 YKT6 KIAA1217 AFG3L2 VPS13A MFN2 SEC61A1 ATP2A2 NEURL4 NUP160 SON | 1.08e-05 | 1496 | 180 | 22 | 32877691 |
| Pubmed | 1.12e-05 | 9 | 180 | 3 | 16382098 | ||
| Pubmed | 1.12e-05 | 9 | 180 | 3 | 16382099 | ||
| Pubmed | 1.12e-05 | 9 | 180 | 3 | 12885400 | ||
| Pubmed | 1.12e-05 | 9 | 180 | 3 | 15746173 | ||
| Pubmed | Large-scale mapping of human protein-protein interactions by mass spectrometry. | KNTC1 CHMP6 ACACA NCKAP1 DSG1 MTHFD1L POLE POLR2B HNRNPM XPO4 CLASP2 OSGEP TRRAP NUP205 TIAM1 SEC61A1 ATP2A2 NEURL4 NUP160 SON | 1.23e-05 | 1284 | 180 | 20 | 17353931 |
| Pubmed | RUFY1 binds Arl8b and mediates endosome-to-TGN CI-M6PR retrieval for cargo sorting to lysosomes. | ACACA HNRNPM HUWE1 XRCC5 NUP205 HSP90AB2P ATP2A2 HSP90AA1 HSP90AA2P HSP90AB1 | 1.36e-05 | 344 | 180 | 10 | 36282215 |
| Pubmed | 1.49e-05 | 29 | 180 | 4 | 21532586 | ||
| Pubmed | BAG-2 acts as an inhibitor of the chaperone-associated ubiquitin ligase CHIP. | 1.59e-05 | 10 | 180 | 3 | 16207813 | |
| Pubmed | 1.59e-05 | 10 | 180 | 3 | 23863468 | ||
| Pubmed | EFCAB5 KNTC1 CLTCL1 HNRNPM ACTN1 XRCC5 OR10G7 NUP205 SEC61A2 NCAPD2 VPS13A PKHD1 GNAI2 OR10G9 ITIH6 SEC61A1 ATP2A2 DNAH8 AP3D1 HSP90AA1 HSP90AB1 | 2.01e-05 | 1442 | 180 | 21 | 35575683 | |
| Pubmed | Reciprocal interaction between SIRT6 and APC/C regulates genomic stability. | MIA3 ACACA POLR2B HNRNPM HUWE1 XRCC5 TRRAP NUP205 ACTR6 MED27 NUP160 | 2.04e-05 | 440 | 180 | 11 | 34244565 |
| Pubmed | Network organization of the huntingtin proteomic interactome in mammalian brain. | PDE1A NCKAP1 GRIN2A ACTN1 HUWE1 TRRAP ACTR6 MFN2 GNAI2 ATP2A2 HSP90AA1 HTT HSP90AB1 | 2.34e-05 | 621 | 180 | 13 | 22794259 |
| Pubmed | ALS/FTD-causing mutation in cyclin F causes the dysregulation of SFPQ. | ACACA DSG1 POLR2B HNRNPM CLASP2 ACTN1 HUWE1 XRCC5 GNAI2 MED27 NUP160 SON HSP90AB1 | 2.46e-05 | 624 | 180 | 13 | 33729478 |
| Pubmed | 2.66e-05 | 2 | 180 | 2 | 25180444 | ||
| Pubmed | 2.66e-05 | 2 | 180 | 2 | 27493027 | ||
| Pubmed | Hsp90 is cleaved by reactive oxygen species at a highly conserved N-terminal amino acid motif. | 2.66e-05 | 2 | 180 | 2 | 22848402 | |
| Pubmed | Therapeutic Potential for CFTR Correctors in Autosomal Recessive Polycystic Kidney Disease. | 2.66e-05 | 2 | 180 | 2 | 34329764 | |
| Pubmed | A mouse tumor-specific transplantation antigen is a heat shock-related protein. | 2.66e-05 | 2 | 180 | 2 | 3458168 | |
| Pubmed | Mechanism of dimer formation of the 90-kDa heat-shock protein. | 2.66e-05 | 2 | 180 | 2 | 7588731 | |
| Interaction | USP50 interactions | 4.68e-07 | 35 | 172 | 6 | int:USP50 | |
| Interaction | AKAP1 interactions | DOCK3 MIA3 MTHFD1L POLR2B FASTKD5 ACTN1 HUWE1 TRRAP FAM83B NUP205 YKT6 FARP1 AFG3L2 NCAPD2 VPS13A MFN2 FAM177A1 | 1.54e-06 | 503 | 172 | 17 | int:AKAP1 |
| Interaction | TRAPPC6B interactions | 1.94e-05 | 39 | 172 | 5 | int:TRAPPC6B | |
| Interaction | ATXN3 interactions | ACACA NCKAP1 DSG1 HNRNPM ACTN1 HUWE1 PTCH1 XRCC5 MFN2 HSP90AB2P SEC61A1 HSP90AA1 HTT HSP90AB1 | 2.55e-05 | 439 | 172 | 14 | int:ATXN3 |
| Interaction | CDC34 interactions | MTHFD1L POLR2B FASTKD5 HUWE1 STN1 NUP205 AFG3L2 NCAPD2 MFN2 ATP2A2 HSP90AA1 HSP90AB1 | 2.61e-05 | 328 | 172 | 12 | int:CDC34 |
| Cytoband | 22q11.21 | 8.03e-05 | 111 | 180 | 5 | 22q11.21 | |
| GeneFamily | Sodium voltage-gated channel alpha subunits | 2.21e-05 | 9 | 118 | 3 | 1203 | |
| GeneFamily | CD molecules|Gamma-glutamyltransferases | 7.39e-05 | 13 | 118 | 3 | 564 | |
| GeneFamily | Heat shock 90kDa proteins | 4.17e-04 | 5 | 118 | 2 | 586 | |
| GeneFamily | Calcium voltage-gated channel subunits | 6.31e-04 | 26 | 118 | 3 | 253 | |
| GeneFamily | ATPases Ca2+ transporting | 1.48e-03 | 9 | 118 | 2 | 1209 | |
| GeneFamily | Anoctamins | 1.84e-03 | 10 | 118 | 2 | 865 | |
| GeneFamily | Maestro heat like repeat containing | 2.24e-03 | 11 | 118 | 2 | 636 | |
| GeneFamily | Collagens | 3.35e-03 | 46 | 118 | 3 | 490 | |
| GeneFamily | Trafficking protein particle complex | 3.65e-03 | 14 | 118 | 2 | 772 | |
| GeneFamily | Endogenous ligands|Minor histocompatibility antigens | 4.49e-03 | 51 | 118 | 3 | 870 | |
| GeneFamily | Dyneins, axonemal | 5.39e-03 | 17 | 118 | 2 | 536 | |
| GeneFamily | Cadherin related | 5.39e-03 | 17 | 118 | 2 | 24 | |
| GeneFamily | Olfactory receptors, family 5 | 6.23e-03 | 112 | 118 | 4 | 152 | |
| CoexpressionAtlas | DevelopingKidney_e15.5_Peripheral blastema_emap-27731_k-means-cluster#3_top-relative-expression-ranked_100 | 6.87e-06 | 60 | 164 | 6 | gudmap_developingKidney_e15.5_Peripheral blastema_100_k3 | |
| CoexpressionAtlas | DevelopingKidney_e15.5_Peripheral blastema_emap-27731_k-means-cluster#2_top-relative-expression-ranked_500 | 3.31e-05 | 206 | 164 | 9 | gudmap_developingKidney_e15.5_Peripheral blastema_500_k2 | |
| CoexpressionAtlas | DevelopingKidney_e15.5_Peripheral blastema_emap-27731_k-means-cluster#2_top-relative-expression-ranked_200 | 3.32e-05 | 116 | 164 | 7 | gudmap_developingKidney_e15.5_Peripheral blastema_200_k2 | |
| CoexpressionAtlas | DevelopingKidney_e15.5_Peripheral blastema_emap-27731_top-relative-expression-ranked_100 | 5.83e-05 | 87 | 164 | 6 | gudmap_developingKidney_e15.5_Peripheral blastema_100 | |
| ToppCell | Tracheal-NucSeq-Stromal-Peri/Epineurial_-NAF_endoneurial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations | BNC2 COL6A3 ADAM21 PTCH1 TENM2 ABCA8 TMEM132C COL24A1 TIAM1 NALCN SCN7A | 4.02e-10 | 193 | 179 | 11 | 549a0b750c860b615aff767ad04c9a9d20f802f0 |
| ToppCell | LPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2 | DOCK3 BNC2 COL6A3 SEMA3C PTCH1 ITIH4 TMEM132C COL24A1 FAT1 NALCN | 4.28e-09 | 185 | 179 | 10 | e64e8c98dd88d91f6501d3fb10b60fd2f3c90af3 |
| ToppCell | Bronchial-NucSeq-Stromal-Peri/Epineurial_-NAF_endoneurial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations | BNC2 PTCH1 TENM2 ABCA8 TMEM132C COL24A1 TIAM1 NALCN SCN7A PKHD1 | 7.82e-09 | 197 | 179 | 10 | 6806ec223e542f0475303698eb78c1cc527f5c6b |
| ToppCell | LPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2 | 6.43e-08 | 185 | 179 | 9 | 6712512100ccef456d2e2bd201d0987986c92ac9 | |
| ToppCell | LPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2 | 7.38e-08 | 188 | 179 | 9 | 3177b2c1723268d330d3e9f24f9e24492ace6286 | |
| ToppCell | Control-Stromal_mesenchymal-Lung_smooth_muscle|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2 | 7.72e-08 | 189 | 179 | 9 | 45e588b2a4ad9e3ff74e22d9d627ed3571f3b8b8 | |
| ToppCell | LPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic|LPS_IL1RA / Treatment groups by lineage, cell group, cell type | 1.25e-07 | 200 | 179 | 9 | 87827041663013f5e7273168dc8709d69840e7ce | |
| ToppCell | facs-Lung-Endomucin-3m-Myeloid-Nonclassical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 2.47e-07 | 157 | 179 | 8 | 0ad242320ada7bcb9e29548d3050bf4fd3a07115 | |
| ToppCell | facs-Lung-Endomucin-3m-Myeloid-non-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 2.47e-07 | 157 | 179 | 8 | fe4c9556806203e57522d1986754ebe5a20aa2de | |
| ToppCell | renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group | 5.66e-07 | 175 | 179 | 8 | 98947a226b5a2ac7091ff9d34243ea7736add973 | |
| ToppCell | renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group | 6.16e-07 | 177 | 179 | 8 | 8e4005fad50e6f919da175f3b9ae58849dbd60b1 | |
| ToppCell | COVID-19-Epithelial-Ionocytes|Epithelial / Condition, Lineage and Cell class | 7.30e-07 | 181 | 179 | 8 | 4a8d4f2709c1b25f908867f1b2fae1d2d0abf1d4 | |
| ToppCell | renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group | 7.30e-07 | 181 | 179 | 8 | 30729f0364f719c044712a51453e22dc2c1a232b | |
| ToppCell | facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 8.26e-07 | 184 | 179 | 8 | 2cbed6462fea2622871bb7e49b0df3d984239281 | |
| ToppCell | facs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 8.26e-07 | 184 | 179 | 8 | ea7a7e2bac46d4d2c31a5d576b38a032b5335062 | |
| ToppCell | facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 8.26e-07 | 184 | 179 | 8 | 2b19a8c5f823e00812908b23e66bb4e563278aff | |
| ToppCell | Adult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Adult / Lineage, Cell type, age group and donor | 8.61e-07 | 185 | 179 | 8 | 673f0c688ae6984bc8027df2da335787924f4137 | |
| ToppCell | LPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2 | 8.61e-07 | 185 | 179 | 8 | 3b2dfc8f4c87be516265dbecfc251276034d0efd | |
| ToppCell | renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Degenerative_Cortical_Intercalated_Cell_Type_A|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group | 8.61e-07 | 185 | 179 | 8 | 9438097e94219c1db922b8507e3a29106d32a923 | |
| ToppCell | LPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2 | 8.96e-07 | 186 | 179 | 8 | 6add08d4ca019ff2864acdd5ec2c66a59a574591 | |
| ToppCell | LPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2 | 9.71e-07 | 188 | 179 | 8 | 293f2fa99f5f96aa7fd2b2a5cc94ff60eeaabe11 | |
| ToppCell | Mesenchymal-myofibroblast_cell|World / Lineage, Cell type, age group and donor | 1.01e-06 | 189 | 179 | 8 | 44e37f88137bb249933eb615235b2cf2ae7f3925 | |
| ToppCell | COVID-19-kidney-TAL|COVID-19 / Disease (COVID-19 only), tissue and cell type | 1.09e-06 | 191 | 179 | 8 | fe55475ce0666ab5122447a813dc2369e24947b8 | |
| ToppCell | Fetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor | 1.14e-06 | 192 | 179 | 8 | 72881b280a415e65f87a80ca1369cbb0b722a0c4 | |
| ToppCell | PCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM1_(8)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung | 1.14e-06 | 192 | 179 | 8 | 4c9d748f209cc1e13d28c8c7f5180ab8522e0fbf | |
| ToppCell | Adult-Immune-alveolar_macrophage_(MARCO_positive)-D175|Adult / Lineage, Cell type, age group and donor | 1.14e-06 | 192 | 179 | 8 | 733491e932350e3c216a626cc49c3cd3fe970a82 | |
| ToppCell | Control-Fibroblasts-Intermediate_pathological_FB|Control / group, cell type (main and fine annotations) | 1.23e-06 | 194 | 179 | 8 | 03a269f75a481ea54aea8e6444605db8d6df493d | |
| ToppCell | PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung | 1.38e-06 | 197 | 179 | 8 | 31a1852911bda38543916585fda34255fd62a134 | |
| ToppCell | Bronchial-NucSeq-Stromal-Peri/Epineurial_|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations | 1.38e-06 | 197 | 179 | 8 | ee8f7def9d5af7b1e636830a4ea1da158d02f25a | |
| ToppCell | Parenchymal-NucSeq-Stromal-Fibroblastic-Fibro_myofibroblast|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations | 1.38e-06 | 197 | 179 | 8 | 6d0d68d460243a0259ada93ebda40fa7b3088eeb | |
| ToppCell | COVID-19-lung-Macrophage_VCANhi_FCN1hi|COVID-19 / Disease (COVID-19 only), tissue and cell type | 1.43e-06 | 198 | 179 | 8 | ea34096bee852a7e996f097fa279381afa8f86ff | |
| ToppCell | facs-Tongue-nan-3m-Epithelial|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 1.43e-06 | 198 | 179 | 8 | 2f03f8897dd7cce6d8296638e14e11ec16bcf624 | |
| ToppCell | facs-Tongue-nan-3m|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 1.43e-06 | 198 | 179 | 8 | f2a4057f038ef7225a5b98a7ab068c30dff4eadd | |
| ToppCell | LPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type | 1.54e-06 | 200 | 179 | 8 | 09537dc25f8b8b4654a7c183827ee1522a41a4e0 | |
| ToppCell | LPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type | 1.54e-06 | 200 | 179 | 8 | 08bf8c00eee6468215edb3611296bfc8784c4d56 | |
| ToppCell | renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group | 2.14e-06 | 146 | 179 | 7 | ec1f793409d1a81c0f9323eb3c82ffe01dae0e44 | |
| ToppCell | renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group | 3.46e-06 | 157 | 179 | 7 | c17c5c01fcb65c453690c265ec4f300ecdfefd34 | |
| ToppCell | wk_15-18-Mesenchymal-Myofibro_&_SMC-Myofibro_2|wk_15-18 / Celltypes from embryonic and fetal-stage human lung | 3.46e-06 | 157 | 179 | 7 | b9d04ee417c0d8ea0801d10f1c54e138587009fd | |
| ToppCell | Adult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D231|Adult / Lineage, Cell type, age group and donor | 5.84e-06 | 170 | 179 | 7 | 269dee5abca9f6aa079f116f0d8f1d198604d9d4 | |
| ToppCell | facs-Marrow-KLS-18m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 6.80e-06 | 174 | 179 | 7 | 9d5dcd46cf346c381dea68ada6665f7fb68114a3 | |
| ToppCell | facs-Marrow-KLS-18m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 6.80e-06 | 174 | 179 | 7 | 53cec5c666c45278a71c21dd9c62a052a97e0fdf | |
| ToppCell | 5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract | 6.80e-06 | 174 | 179 | 7 | f90ca117b729436cf452e2ddcec26ba525c5c13b | |
| ToppCell | renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group | 6.80e-06 | 174 | 179 | 7 | 5f4436863a40f8bca46e2989bca66c02b6be88d4 | |
| ToppCell | renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group | 7.06e-06 | 175 | 179 | 7 | 77c16e615c0fb9c83f29d7e0a547be72635fac81 | |
| ToppCell | renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group | 7.33e-06 | 176 | 179 | 7 | 25ebc8716aa44e44fce577701e3e82c6745a75ab | |
| ToppCell | renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group | 7.33e-06 | 176 | 179 | 7 | c2c4306476989bc2fb30dab00250ef7915842f13 | |
| ToppCell | renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group | 7.89e-06 | 178 | 179 | 7 | 51d2188406f04329311b2efd1108fc36617a860e | |
| ToppCell | renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group | 8.19e-06 | 179 | 179 | 7 | e6ae070b4c52ba08167c7d64ea4cfbac0454c1bf | |
| ToppCell | Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor | 8.19e-06 | 179 | 179 | 7 | 815b959ce8721c5ded70c0ca6e318dafc691746e | |
| ToppCell | LPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2 | 8.19e-06 | 179 | 179 | 7 | 02c90d8306016365ed811f0c63cfb3ac7b85464c | |
| ToppCell | renal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Monocytic-Non-classical_Monocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group | 8.80e-06 | 181 | 179 | 7 | 8657d35cd3dff6c89d0fde67d7e7e81e1d6c8884 | |
| ToppCell | COVID-19-kidney-CD-IC-B|COVID-19 / Disease (COVID-19 only), tissue and cell type | 9.12e-06 | 182 | 179 | 7 | ee6a8c356bbbdae55e4ea858337e079491f9f4aa | |
| ToppCell | COVID-19-kidney-PCT-S1|COVID-19 / Disease (COVID-19 only), tissue and cell type | 9.45e-06 | 183 | 179 | 7 | 6878d14026c3df6aa12e45dfad94b32fa9d9b0b7 | |
| ToppCell | Control-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2 | 9.45e-06 | 183 | 179 | 7 | 7eae9b3b4d1c9b135fa7cff348393d4adec474b4 | |
| ToppCell | COVID-19-kidney-CD-IC-A|kidney / Disease (COVID-19 only), tissue and cell type | 9.45e-06 | 183 | 179 | 7 | 5c7597a5b2bf6a481ca2c7e68560179214150fa0 | |
| ToppCell | LPS_only-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2 | 9.45e-06 | 183 | 179 | 7 | 12daaea821e49bc94a01e2496331e92a80d27339 | |
| ToppCell | Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Children_(3_yrs) / Lineage, Cell type, age group and donor | 1.01e-05 | 185 | 179 | 7 | 98b8ee42b89d97e4c9db01740e0c193503c68f2c | |
| ToppCell | COVID-19-Epithelial_cells-Airway_club|COVID-19 / group, cell type (main and fine annotations) | 1.01e-05 | 185 | 179 | 7 | cfe6fd73d817e173fe803bc1683c291d9bcb8608 | |
| ToppCell | renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group | 1.05e-05 | 186 | 179 | 7 | a6ef5d5944af5689b5f27bef89cd05645eedbe50 | |
| ToppCell | Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|World / Lineage, Cell type, age group and donor | 1.09e-05 | 187 | 179 | 7 | 81cc8435b2704a9a8287b3f54acaae0f11dd4ac7 | |
| ToppCell | renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group | 1.09e-05 | 187 | 179 | 7 | f124d2c699b717b7c02a1a70493f515b83dc2f4c | |
| ToppCell | Fetal_29-31_weeks-Mesenchymal-myofibroblast_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor | 1.09e-05 | 187 | 179 | 7 | c104fbfef2d0bef64077ac721edf2379fd59d547 | |
| ToppCell | Control-Fibroblasts-Other_FB|Control / group, cell type (main and fine annotations) | 1.09e-05 | 187 | 179 | 7 | bd3739c4a52aa1ba5deffd778e113a9800f7e158 | |
| ToppCell | renal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Monocytic-Non-classical_Monocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group | 1.13e-05 | 188 | 179 | 7 | 4e27ada1bda88811b73376c8a6136cbfc83bfdb9 | |
| ToppCell | renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group | 1.13e-05 | 188 | 179 | 7 | e751cff2ac8fbc1487766c1871fcc5d1005286b0 | |
| ToppCell | COVID-19-Epithelial-Ionocytes|COVID-19 / Condition, Lineage and Cell class | 1.13e-05 | 188 | 179 | 7 | a581cb9528d0febbf3addbb4f6bc140f91a584e6 | |
| ToppCell | human_hepatoblastoma-Tumor_cells-T5|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells) | 1.13e-05 | 188 | 179 | 7 | b070a0667f1ee9b825b267b6c389b7c42fc436f9 | |
| ToppCell | renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group | 1.17e-05 | 189 | 179 | 7 | 71397e993a77d70b2eeede240bdfc7660b558987 | |
| ToppCell | renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group | 1.17e-05 | 189 | 179 | 7 | 4eea4759520c312bd17a681034d8074e47093d2b | |
| ToppCell | LPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2 | 1.17e-05 | 189 | 179 | 7 | 7ab1cfc1657277858339f7258a0c4ae9cb42fdf8 | |
| ToppCell | Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor | 1.17e-05 | 189 | 179 | 7 | 203c80030df08ae112f9ae4043709f455d87ce89 | |
| ToppCell | renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group | 1.17e-05 | 189 | 179 | 7 | e32172ad09e93f6ac6ea2b92145b2b73003f7970 | |
| ToppCell | kidney_cells-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group | 1.21e-05 | 190 | 179 | 7 | bb3b396d78887d5d6f93a05c8ed4d703591bf33f | |
| ToppCell | Control-PLT_5|World / Disease Group and Platelet Clusters | 1.21e-05 | 126 | 179 | 6 | 4ba753c4e83eb1d41964edfa22135e047f06c481 | |
| ToppCell | Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor | 1.25e-05 | 191 | 179 | 7 | 34cc997e4e5c727495f321e6807a84aa124da486 | |
| ToppCell | Control-Stromal_mesenchymal|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2 | 1.25e-05 | 191 | 179 | 7 | 14057205ddb9b4bbc582d1358d13cf36d979a61b | |
| ToppCell | LPS_only-Stromal_mesenchymal-Lung_smooth_muscle|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2 | 1.25e-05 | 191 | 179 | 7 | 08042952431ca1a6fd7dfc13f36eb28643979598 | |
| ToppCell | Control-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2 | 1.25e-05 | 191 | 179 | 7 | b133ee1c0e58d00ddd2e4e05b01fd04947524c18 | |
| ToppCell | COVID-19-kidney-Mito-rich_Distal|COVID-19 / Disease (COVID-19 only), tissue and cell type | 1.25e-05 | 191 | 179 | 7 | 0965f621ebcd92ccdeb21cc27022180ce3cfe910 | |
| ToppCell | renal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Monocytic-Non-classical_Monocyte|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group | 1.25e-05 | 191 | 179 | 7 | 47a2afc4102199b4bc76bd01b2967c8016186462 | |
| ToppCell | nucseq-Mesenchymal-Myocytic-Myocytic_2-SCMF|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2 | 1.29e-05 | 192 | 179 | 7 | 67e845e513e76e820f55e2f0d15eb16f2944d05c | |
| ToppCell | Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2|Fetal_29-31_weeks / Lineage, Cell type, age group and donor | 1.29e-05 | 192 | 179 | 7 | fb2f0e897228f808d9ff734ad05e9b49dc38fa50 | |
| ToppCell | COVID-19-Heart-CM_+_EC_+_Pericyte|Heart / Disease (COVID-19 only), tissue and cell type | 1.34e-05 | 193 | 179 | 7 | dd5378a1ef8eb0eda9a3aae62f3c2f3a1402bda0 | |
| ToppCell | Epithelial-club_cell|World / Lineage, Cell type, age group and donor | 1.34e-05 | 193 | 179 | 7 | 2bdd09004fa433550958ec42ba4b06271a4aaf7c | |
| ToppCell | PCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM1_(8)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung | 1.34e-05 | 193 | 179 | 7 | e2b455387d1de7812305200a2041a0f4759a6f54 | |
| ToppCell | Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor | 1.38e-05 | 194 | 179 | 7 | 011e14d9ed1393275f892060e7708ffadcd0767f | |
| ToppCell | PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung | 1.38e-05 | 194 | 179 | 7 | b1bb0f846d2865efdd9bc8842b16b9d069785882 | |
| ToppCell | COVID-19-Heart-CM_1|Heart / Disease (COVID-19 only), tissue and cell type | 1.43e-05 | 195 | 179 | 7 | f1ef50331eda8f1239dba6ea970df4eaccf032f1 | |
| ToppCell | PCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung | 1.43e-05 | 195 | 179 | 7 | c5d2d9f12fd893331c9de261af30607d845d4f6a | |
| ToppCell | COVID-19-Heart-CM_2|Heart / Disease (COVID-19 only), tissue and cell type | 1.43e-05 | 195 | 179 | 7 | 75fc81bddb246dca3b437fb60827b1d4fe416405 | |
| ToppCell | PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung | 1.43e-05 | 195 | 179 | 7 | 0e55fa5b3cbeb7baee3d4ac272a3bf80381ec937 | |
| ToppCell | renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Monocytic-Non-classical_Monocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group | 1.43e-05 | 195 | 179 | 7 | 10ce1b6961f10372d1f65388cbf3626a5fcd6840 | |
| ToppCell | RA-02._Fibroblast_II|RA / Chamber and Cluster_Paper | 1.43e-05 | 195 | 179 | 7 | 6a02ebbeb3199447ddce64d92d8809436e040eba | |
| ToppCell | COVID-19-kidney-Fibroblast-2|COVID-19 / Disease (COVID-19 only), tissue and cell type | 1.43e-05 | 195 | 179 | 7 | 3d62ce1c696f47d4d7eb0c5bb0eec2c24b122bb2 | |
| ToppCell | Adult-Immune-alveolar_macrophage_(MARCO_positive)|Adult / Lineage, Cell type, age group and donor | 1.43e-05 | 195 | 179 | 7 | 55e25f702af19146a161861cfd15f40bbda1dc35 | |
| ToppCell | kidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group | 1.43e-05 | 195 | 179 | 7 | f7d9adadd37209ce1a38e5d621607b9c9270fed8 | |
| ToppCell | Bronchial-NucSeq-Stromal-Fibroblastic-Fibro_myofibroblast|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations | 1.43e-05 | 195 | 179 | 7 | f5e91ce20a7ce528dc4c1a968c7bf096bf45c528 | |
| ToppCell | Bronchial-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Club|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations | 1.48e-05 | 196 | 179 | 7 | ed76eeb37400ca154feae9b7ebaddb6c434f8b81 | |
| ToppCell | renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group | 1.48e-05 | 196 | 179 | 7 | 2b36b9a40fe415917afccff99ad9c3474e087d0d | |
| ToppCell | PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung | 1.48e-05 | 196 | 179 | 7 | 1450cb69c5bf469e97c03bf1890f6f7c54165b8a | |
| Drug | lamotrigine | CACNA1F CACNA1S GRIN2A PTCH1 CATSPER1 SCN3A SCN5A SCN7A CACNA1G | 3.47e-07 | 116 | 179 | 9 | CID000003878 |
| Drug | azaquinone | 4.78e-07 | 3 | 179 | 3 | CID000099132 | |
| Drug | guanosine 3',5'-cyclic monophosphoric acid | KNTC1 CACNA1F CACNA1S PDE1A PDE1C CLTCL1 ZBTB17 POLR2B CFTR NTSR1 GRIN2A HCN2 CATSPER1 ACTR6 CACNA1G HSP90AA1 HSP90AA2P HSP90AB1 | 7.49e-07 | 577 | 179 | 18 | CID000000295 |
| Drug | dexamethasone 21-mesylate | 6.25e-06 | 16 | 179 | 4 | CID000063041 | |
| Drug | Verapamil | 6.25e-06 | 16 | 179 | 4 | DB00661 | |
| Drug | gabapentin | CACNA1F CACNA1S GRIN2A CATSPER1 KCNJ1 SCN3A SCN5A SCN7A CACNA1G | 7.97e-06 | 169 | 179 | 9 | CID000003446 |
| Drug | Zonisamide | 8.12e-06 | 17 | 179 | 4 | DB00909 | |
| Drug | verapamil | CACNA1F CACNA1S CFTR KCNG3 ABCA8 CATSPER1 KCNJ1 SCN3A SCN5A SCN7A CACNA1G GNAI2 ATP2A2 TAP1 ATP2B4 | 8.19e-06 | 490 | 179 | 15 | CID000002520 |
| Drug | Adenosine-5'-Diphosphate | 8.79e-06 | 36 | 179 | 5 | DB03431 | |
| Drug | phenytoin | CACNA1F CACNA1S COL6A3 PTCH1 PLXNB2 CATSPER1 SCN3A SCN5A SCN7A CACNA1G | 9.67e-06 | 219 | 179 | 10 | CID000001775 |
| Drug | NSC7524 | CACNA1F CACNA1S PDE1C GRIN2A CATSPER1 SCN3A SCN5A SCN7A CACNA1G | 1.45e-05 | 182 | 179 | 9 | CID000005657 |
| Drug | NSC330499 | 1.63e-05 | 7 | 179 | 3 | CID000433447 | |
| Drug | phenyldichloroarsine | 2.60e-05 | 8 | 179 | 3 | CID000012762 | |
| Drug | 9-phenanthrol | 2.60e-05 | 8 | 179 | 3 | CID000010229 | |
| Drug | arachidonyl trifluoromethyl ketone; Down 200; 10uM; MCF7; HG-U133A | 2.82e-05 | 198 | 179 | 9 | 594_DN | |
| Drug | Cinnarizine | 3.88e-05 | 9 | 179 | 3 | DB00568 | |
| Drug | 5,8-quinolinedione | 3.88e-05 | 9 | 179 | 3 | CID000388306 | |
| Drug | Verteporfin [129497-78-5]; Down 200; 2.8uM; HL60; HT_HG-U133A | 4.03e-05 | 160 | 179 | 8 | 6133_DN | |
| Drug | benzoquinone | APAF1 GRIN2A ATP2A2 TAP1 ATP2B4 HSP90AA1 HTT HSP90AA2P HSP90AB1 | 4.30e-05 | 209 | 179 | 9 | CID000004650 |
| Drug | chlorothalonil | 4.40e-05 | 162 | 179 | 8 | CID000015910 | |
| Drug | felodipine | 5.94e-05 | 169 | 179 | 8 | CID000003333 | |
| Drug | 3-amino-5-chlorobenzoic acid | 6.15e-05 | 2 | 179 | 2 | CID010986726 | |
| Drug | monocillin III | 6.15e-05 | 2 | 179 | 2 | CID006478910 | |
| Drug | pochonin A | 6.15e-05 | 2 | 179 | 2 | CID006478909 | |
| Drug | PU-H71 | 6.15e-05 | 2 | 179 | 2 | CID009549213 | |
| Drug | Phenytoin | 6.15e-05 | 2 | 179 | 2 | DB00252 | |
| Drug | 9-Butyl-8-(3,4,5-Trimethoxybenzyl)-9h-Purin-6-Amine | 6.15e-05 | 2 | 179 | 2 | DB02754 | |
| Drug | 1uyc | 6.15e-05 | 2 | 179 | 2 | CID000448969 | |
| Drug | PU-9 | 6.15e-05 | 2 | 179 | 2 | CID000448971 | |
| Drug | P u 0 | 6.15e-05 | 2 | 179 | 2 | CID000448974 | |
| Drug | 2qf6 | 6.15e-05 | 2 | 179 | 2 | CID013373715 | |
| Drug | Geldanamycin | 6.15e-05 | 2 | 179 | 2 | DB02424 | |
| Drug | CHEBI:42139 | 6.15e-05 | 2 | 179 | 2 | CID011562562 | |
| Drug | 2qfo | 6.15e-05 | 2 | 179 | 2 | CID000600769 | |
| Drug | 3eko | 6.15e-05 | 2 | 179 | 2 | CID011160307 | |
| Drug | 8-(6-BROMO-BENZO[1,3]DIOXOL-5-YLSULFANYL)-9-(3-ISOPROPYLAMINO-PROPYL)-ADENINE | 6.15e-05 | 2 | 179 | 2 | DB07877 | |
| Drug | 1uyi | 6.15e-05 | 2 | 179 | 2 | CID005289232 | |
| Drug | 4-[4-(2,3-DIHYDRO-1,4-BENZODIOXIN-6-YL)-3-METHYL-1H-PYRAZOL-5-YL]-6-ETHYLBENZENE-1,3-DIOL | 6.15e-05 | 2 | 179 | 2 | DB07594 | |
| Drug | NSC683666 | 6.15e-05 | 2 | 179 | 2 | CID005469153 | |
| Drug | H 64 | 6.15e-05 | 2 | 179 | 2 | CID006914564 | |
| Drug | SureCN4151355 | 6.15e-05 | 2 | 179 | 2 | CID015942101 | |
| Drug | NSC729693 | 6.15e-05 | 2 | 179 | 2 | CID011842508 | |
| Drug | bepridil | 6.35e-05 | 126 | 179 | 7 | CID000002351 | |
| Drug | TM02 | 6.53e-05 | 28 | 179 | 4 | CID000012902 | |
| Drug | silver nanoparticles | 6.72e-05 | 172 | 179 | 8 | CID000023954 | |
| Drug | riluzole | 7.29e-05 | 174 | 179 | 8 | CID000005070 | |
| Drug | Mibefradil | 7.53e-05 | 11 | 179 | 3 | DB01388 | |
| Drug | Pu-3 | 7.53e-05 | 11 | 179 | 3 | CID000448965 | |
| Drug | tocainide | 8.63e-05 | 30 | 179 | 4 | CID000038945 | |
| Drug | DMAB | 8.93e-05 | 133 | 179 | 7 | CID000006053 | |
| Drug | 4-amino-2,6-dinitrotoluene | CHMP6 XRCC5 HCN2 GGT1 NUP205 FAT1 MLH3 AFG3L2 MFN2 ATP2A2 AP3D1 NR1I3 HSP90AA1 HSP90AB1 | 1.02e-04 | 541 | 179 | 14 | ctd:C035207 |
| Drug | IAA-94 | 1.18e-04 | 61 | 179 | 5 | CID000003667 | |
| Drug | CNS 1145 | 1.26e-04 | 33 | 179 | 4 | CID000190902 | |
| Drug | IHC-64 | 1.26e-04 | 33 | 179 | 4 | CID000162753 | |
| Drug | NSC 255110 | 1.29e-04 | 13 | 179 | 3 | CID000318505 | |
| Drug | potassium | CACNA1F CACNA1S CLTCL1 CFTR GRIN2A PTCH1 KCNG3 HCN2 GGT1 PLA2R1 CATSPER1 SLC11A1 KCNJ1 SCN3A ATP6V0A4 SCN5A SCN7A CACNA1G ATP2A2 ATP2B4 | 1.37e-04 | 1008 | 179 | 20 | CID000000813 |
| Drug | isradipine | 1.40e-04 | 100 | 179 | 6 | CID000003784 | |
| Drug | Trimethobenzamide hydrochloride [554-92-7]; Up 200; 9.4uM; MCF7; HT_HG-U133A | 1.44e-04 | 192 | 179 | 8 | 4180_UP | |
| Drug | nimodipine | 1.53e-04 | 145 | 179 | 7 | CID000004497 | |
| Drug | Metaraminol bitartrate [33402-03-8]; Down 200; 8.6uM; PC3; HT_HG-U133A | 1.61e-04 | 195 | 179 | 8 | 7368_DN | |
| Drug | Fosinopril | 1.63e-04 | 14 | 179 | 3 | ctd:D017328 | |
| Drug | haloperidol; Up 200; 10uM; MCF7; HT_HG-U133A | 1.72e-04 | 197 | 179 | 8 | 5563_UP | |
| Drug | Idoxuridine [54-42-2]; Down 200; 11.2uM; PC3; HG-U133A | 1.72e-04 | 197 | 179 | 8 | 1899_DN | |
| Drug | Trioxsalen [3902-71-4]; Down 200; 17.6uM; MCF7; HT_HG-U133A | 1.72e-04 | 197 | 179 | 8 | 6216_DN | |
| Drug | sodium 4-phenylbutyrate; Down 200; 1000uM; MCF7; HG-U133A | 1.78e-04 | 198 | 179 | 8 | 407_DN | |
| Drug | Fluocinonide [356-12-7]; Down 200; 8uM; PC3; HT_HG-U133A | 1.78e-04 | 198 | 179 | 8 | 3757_DN | |
| Drug | pochonin D | 1.83e-04 | 3 | 179 | 2 | CID006478913 | |
| Drug | d 1 v | 1.83e-04 | 3 | 179 | 2 | CID000683940 | |
| Drug | AC1MD0RC | 1.83e-04 | 3 | 179 | 2 | CID002829073 | |
| Drug | HM-9 | 1.83e-04 | 3 | 179 | 2 | CID000433437 | |
| Drug | Glyoxylspermidine | 1.83e-04 | 3 | 179 | 2 | CID000133564 | |
| Drug | Bay K 8644 | 1.89e-04 | 150 | 179 | 7 | CID000002303 | |
| Drug | AC1L9PMA | 2.03e-04 | 15 | 179 | 3 | CID000451405 | |
| Drug | procaine | 2.13e-04 | 153 | 179 | 7 | CID000004914 | |
| Disease | generalized epilepsy with febrile seizures plus 2 (implicated_via_orthology) | 2.39e-07 | 10 | 174 | 4 | DOID:0111294 (implicated_via_orthology) | |
| Disease | Dravet syndrome (implicated_via_orthology) | 2.39e-07 | 10 | 174 | 4 | DOID:0080422 (implicated_via_orthology) | |
| Disease | generalized epilepsy with febrile seizures plus (implicated_via_orthology) | 5.57e-07 | 12 | 174 | 4 | DOID:0060170 (implicated_via_orthology) | |
| Disease | coronary artery disease | COL6A3 SEMA3C PDE1A PDE1C MIA3 CLTCL1 SWAP70 MTHFD1L CFTR HNRNPM PMEPA1 ABCA8 ITIH4 STN1 FAM83B SLC15A1 FARP1 KIAA1217 PKHD1 GNAI2 DENND5A NUP160 WNK2 | 6.28e-07 | 1194 | 174 | 23 | EFO_0001645 |
| Disease | aflatoxins-related hepatocellular carcinoma (biomarker_via_orthology) | 6.93e-06 | 7 | 174 | 3 | DOID:5022 (biomarker_via_orthology) | |
| Disease | myocardial infarction | COL6A3 PDE1A MIA3 SWAP70 PMEPA1 STN1 SLC15A1 GNAI2 ATP2A2 AP3D1 HTT | 8.04e-06 | 350 | 174 | 11 | EFO_0000612 |
| Disease | alcohol dependence (biomarker_via_orthology) | 1.10e-05 | 8 | 174 | 3 | DOID:0050741 (biomarker_via_orthology) | |
| Disease | Colorectal Carcinoma | ACACA ZNF560 TNFSF13 MTHFD1L POLE CFTR GRIN2A ABCA8 FAT1 MLH3 TIAM1 TLR2 VPS13A PKHD1 DNAH8 | 1.94e-05 | 702 | 174 | 15 | C0009402 |
| Disease | bronchiectasis (is_implicated_in) | 3.46e-05 | 2 | 174 | 2 | DOID:9563 (is_implicated_in) | |
| Disease | epilepsy (implicated_via_orthology) | 5.40e-05 | 163 | 174 | 7 | DOID:1826 (implicated_via_orthology) | |
| Disease | Drug habituation | 6.38e-05 | 115 | 174 | 6 | C0013170 | |
| Disease | Drug abuse | 6.38e-05 | 115 | 174 | 6 | C0013146 | |
| Disease | Prescription Drug Abuse | 6.38e-05 | 115 | 174 | 6 | C4316881 | |
| Disease | Substance-Related Disorders | 6.38e-05 | 115 | 174 | 6 | C0236969 | |
| Disease | Drug Use Disorders | 6.38e-05 | 115 | 174 | 6 | C0013222 | |
| Disease | Drug Dependence | 6.38e-05 | 115 | 174 | 6 | C1510472 | |
| Disease | Substance Dependence | 6.38e-05 | 115 | 174 | 6 | C0038580 | |
| Disease | Substance Use Disorders | 6.38e-05 | 115 | 174 | 6 | C0038586 | |
| Disease | Organic Mental Disorders, Substance-Induced | 6.38e-05 | 115 | 174 | 6 | C0029231 | |
| Disease | Substance abuse problem | 6.69e-05 | 116 | 174 | 6 | C0740858 | |
| Disease | Epilepsies, Partial | 1.03e-04 | 3 | 174 | 2 | C0014547 | |
| Disease | developmental disorder of mental health (implicated_via_orthology) | 2.01e-04 | 49 | 174 | 4 | DOID:0060037 (implicated_via_orthology) | |
| Disease | Timothy syndrome (implicated_via_orthology) | 2.06e-04 | 4 | 174 | 2 | DOID:0060173 (implicated_via_orthology) | |
| Disease | depressive symptom measurement | 2.34e-04 | 426 | 174 | 10 | EFO_0007006 | |
| Disease | Colorectal Neoplasms | 2.52e-04 | 277 | 174 | 8 | C0009404 | |
| Disease | abdominal adipose tissue measurement | 2.73e-04 | 53 | 174 | 4 | EFO_0803316 | |
| Disease | Choledochal Cyst, Type I | 3.42e-04 | 5 | 174 | 2 | C0009439 | |
| Disease | Choledochal Cyst, Type II | 3.42e-04 | 5 | 174 | 2 | C1257796 | |
| Disease | Choledochal Cyst, Type III | 3.42e-04 | 5 | 174 | 2 | C1257797 | |
| Disease | carotid stenosis (implicated_via_orthology) | 3.42e-04 | 5 | 174 | 2 | DOID:13001 (implicated_via_orthology) | |
| Disease | Choledochal Cyst, Type IV | 3.42e-04 | 5 | 174 | 2 | C1257798 | |
| Disease | Choledochal Cyst, Type V | 3.42e-04 | 5 | 174 | 2 | C1257799 | |
| Disease | Choledochal Cyst | 3.42e-04 | 5 | 174 | 2 | C0008340 | |
| Disease | Mood Disorders | 5.00e-04 | 168 | 174 | 6 | C0525045 | |
| Disease | muscular atrophy (biomarker_via_orthology) | 6.58e-04 | 29 | 174 | 3 | DOID:767 (biomarker_via_orthology) | |
| Disease | amino acid measurement | LVRN ANO2 CLTCL1 OR5T2 GTDC1 PMEPA1 COL24A1 PLA2R1 FARP1 OR4X1 WNK2 HTT | 7.31e-04 | 678 | 174 | 12 | EFO_0005134 |
| Disease | colorectal cancer (is_implicated_in) | 7.71e-04 | 121 | 174 | 5 | DOID:9256 (is_implicated_in) | |
| Disease | Leprosy | 9.46e-04 | 8 | 174 | 2 | C0023343 | |
| Disease | leprosy (is_implicated_in) | 9.46e-04 | 8 | 174 | 2 | DOID:1024 (is_implicated_in) | |
| Disease | basal cell carcinoma (is_marker_for) | 9.46e-04 | 8 | 174 | 2 | DOID:2513 (is_marker_for) | |
| Disease | NRF2 measurement | 9.46e-04 | 8 | 174 | 2 | EFO_0009794 | |
| Disease | Spinocerebellar Ataxia Type 2 | 1.05e-03 | 34 | 174 | 3 | C0752121 | |
| Disease | Spinocerebellar Ataxia Type 1 | 1.05e-03 | 34 | 174 | 3 | C0752120 | |
| Disease | Spinocerebellar Ataxia Type 5 | 1.05e-03 | 34 | 174 | 3 | C0752123 | |
| Disease | Spinocerebellar Ataxia Type 7 | 1.05e-03 | 34 | 174 | 3 | C0752125 | |
| Disease | Spinocerebellar Ataxia Type 6 (disorder) | 1.05e-03 | 34 | 174 | 3 | C0752124 | |
| Disease | Ataxia, Spinocerebellar | 1.05e-03 | 34 | 174 | 3 | C0087012 | |
| Disease | Spinocerebellar Ataxia Type 4 | 1.15e-03 | 35 | 174 | 3 | C0752122 | |
| Disease | Autosomal Recessive Polycystic Kidney Disease | 1.21e-03 | 9 | 174 | 2 | C0085548 | |
| Disease | macrophage inflammatory protein 1b measurement | 1.30e-03 | 136 | 174 | 5 | EFO_0008219 | |
| Disease | Intellectual Disability | 1.41e-03 | 447 | 174 | 9 | C3714756 | |
| Disease | age of onset of depressive disorder, wellbeing measurement | 1.51e-03 | 10 | 174 | 2 | EFO_0007869, OBA_2040166 | |
| Disease | MYCOBACTERIUM TUBERCULOSIS, SUSCEPTIBILITY TO (finding) | 1.51e-03 | 10 | 174 | 2 | C1834752 | |
| Disease | Mycobacterium tuberculosis, susceptibility to | 1.51e-03 | 10 | 174 | 2 | cv:C1834752 | |
| Disease | MYCOBACTERIUM TUBERCULOSIS, SUSCEPTIBILITY TO | 1.51e-03 | 10 | 174 | 2 | 607948 | |
| Disease | pancreatitis (biomarker_via_orthology) | 1.58e-03 | 39 | 174 | 3 | DOID:4989 (biomarker_via_orthology) | |
| Disease | diffuse scleroderma (is_implicated_in) | 1.84e-03 | 11 | 174 | 2 | DOID:1580 (is_implicated_in) | |
| Disease | autosomal recessive polycystic kidney disease (biomarker_via_orthology) | 1.84e-03 | 11 | 174 | 2 | DOID:0110861 (biomarker_via_orthology) | |
| Disease | pulmonary tuberculosis (is_implicated_in) | 1.95e-03 | 42 | 174 | 3 | DOID:2957 (is_implicated_in) | |
| Disease | gallbladder carcinoma (is_marker_for) | 2.19e-03 | 12 | 174 | 2 | DOID:4948 (is_marker_for) | |
| Disease | visceral adipose tissue measurement | 2.31e-03 | 481 | 174 | 9 | EFO_0004765 | |
| Disease | hypertension | 2.39e-03 | 307 | 174 | 7 | EFO_0000537 | |
| Disease | ovarian serous carcinoma | 2.54e-03 | 46 | 174 | 3 | EFO_1001516 | |
| Disease | lifestyle measurement | 2.79e-03 | 235 | 174 | 6 | EFO_0010724 | |
| Disease | frontal fibrosing alopecia | 2.87e-03 | 48 | 174 | 3 | EFO_0009855 | |
| Disease | ocular hypertension, response to triamcinolone acetonide | 3.04e-03 | 49 | 174 | 3 | EFO_0006954, EFO_1001069 | |
| Disease | pulmonary fibrosis (biomarker_via_orthology) | 3.22e-03 | 50 | 174 | 3 | DOID:3770 (biomarker_via_orthology) | |
| Disease | HIV Infections | 3.28e-03 | 103 | 174 | 4 | C0019693 | |
| Disease | HIV Coinfection | 3.28e-03 | 103 | 174 | 4 | C4505456 | |
| Disease | treatment-resistant hypertension | 4.02e-03 | 109 | 174 | 4 | EFO_1002006 | |
| Disease | cognitive function measurement | LVRN DOCK3 EFCAB5 KNTC1 PDE1C XPO4 GRIN2A PTCH1 GTDC1 PLXNB2 ABCA8 FARP1 KIAA1217 PKHD1 GNAI2 MED27 WNK2 | 4.95e-03 | 1434 | 174 | 17 | EFO_0008354 |
| Disease | esophageal adenocarcinoma | 4.97e-03 | 18 | 174 | 2 | EFO_0000478 | |
| Disease | neuroticism measurement, wellbeing measurement, depressive symptom measurement | 5.53e-03 | 19 | 174 | 2 | EFO_0007006, EFO_0007660, EFO_0007869 | |
| Disease | intrahepatic cholangiocarcinoma (is_marker_for) | 5.53e-03 | 19 | 174 | 2 | DOID:4928 (is_marker_for) |
| Peptide | Gene | Start | Entry |
|---|---|---|---|
| VDVVFQENEVMVLAV | 926 | O14727 | |
| NFTSIQESMNEILFE | 101 | Q9GZN1 | |
| MVDTIKNFVNTFIQF | 366 | Q9Y6F7 | |
| VFLTGTFTQEVMIQI | 466 | Q9Y6F7 | |
| VVTFQAFIDFMSRET | 806 | P12814 | |
| NLTTTEVVMENVTAF | 386 | P13569 | |
| TVMLVAQTFAEVEIR | 461 | Q8NEC5 | |
| VNISFAMSAILDVNE | 66 | A5X5Y0 | |
| VEMDGFNTTTNVVIL | 436 | Q9Y4W6 | |
| EIVQSNVVFDISSLM | 161 | Q6ZN30 | |
| VQEDVFLVVNIVDSM | 231 | Q9UKJ8 | |
| LATLFFDEVVKQMVA | 196 | Q9H8M1 | |
| SEREVFFMNTQSIVQ | 956 | Q13085 | |
| VVSVDTARTLFNQVM | 61 | Q16548 | |
| QIVELQQFFSNMLEE | 941 | Q6Q4G3 | |
| IIFQNLVMFLSVLVD | 911 | Q9NQ90 | |
| SAEVFQVQREALFMK | 996 | Q8TF21 | |
| ISSLEAMVQSIEFTQ | 81 | Q96FZ7 | |
| ISEEYNVAVFVTNQM | 256 | Q14565 | |
| QAQFDIAVASEIMAV | 601 | Q6UB35 | |
| TIVFNTFVLMQLFNE | 961 | P23634 | |
| FATFEGDDVVMLQVV | 371 | Q9NUZ1 | |
| EAQYVFTIQSIVMAQ | 1001 | O14617 | |
| STEMLRNFIQTEAVV | 126 | O00189 | |
| FLETESTFMTNQLVD | 186 | Q14624 | |
| TATAFFVELLQMEQV | 981 | Q68CQ1 | |
| DNVFLFLMESVVVSE | 366 | Q92621 | |
| QILASVSVVFVIVSM | 171 | Q8TAE7 | |
| QLAFETMSVISVVTN | 556 | Q9NW15 | |
| FADINTFMVLQVIKF | 161 | Q14994 | |
| AIQDQLVFSVSVEML | 156 | Q7L8S5 | |
| FMTTAVDLVITEVQE | 406 | Q9Y3P9 | |
| LIINLFVAVIMDNFD | 1431 | O60840 | |
| SQSVEVIESFAINME | 2851 | Q14517 | |
| VDVTEVVRNMTSEFF | 336 | A6NGU5 | |
| TVMVNLFVNDTVSNE | 836 | Q8N6Y1 | |
| EVETFAFQAEIAQLM | 11 | P08238 | |
| TSANEMVIFVNIGLV | 191 | Q8NGN6 | |
| DIFLNELVMFTVGVV | 191 | Q8NGS2 | |
| EFIVQTASYMLVNEN | 66 | O95751 | |
| TVISSSFVNVNFEME | 181 | Q8N128 | |
| ATVKVVIQVNTFMSF | 231 | P30989 | |
| FSDVVMQSEVFVSDI | 246 | Q9ULD2 | |
| IFATQFNMEVEIITS | 331 | Q7Z3F1 | |
| EVETFAFQAEIAQLM | 11 | Q58FF8 | |
| AVFEVSDTMSAVLQV | 331 | P04424 | |
| FEQSIEAVQAISMFN | 251 | P52272 | |
| EQIFRVSFVLEMINT | 186 | Q5JUK3 | |
| QMFSVSEISTVAQEI | 1156 | Q5CZC0 | |
| SMVQIITGQLVESFD | 256 | Q5T0W9 | |
| VQTVTVFFEKQTRLM | 426 | Q63HM2 | |
| EVVDASLSVIAQTFM | 1706 | O15031 | |
| VAVRVNMETFQVQVI | 41 | Q9UHC1 | |
| QAFFFMDLATTEVAI | 101 | Q8NHC6 | |
| MVATNNVTEIIFVGF | 1 | Q8NH49 | |
| AVQMFFFVALATVEN | 96 | Q96R09 | |
| TMVAQSQIGFIDFIV | 411 | P54750 | |
| TMVAQSQVGFIDFIV | 421 | Q14123 | |
| ESFFQEVELVLDMFN | 691 | Q96JB1 | |
| RMKTIFTQEIFTEQV | 516 | Q9H0H0 | |
| VVENMDILVQIRSNF | 871 | P55160 | |
| FFSEDGIVLESQMVL | 1196 | P50748 | |
| ALSVSFIINLFVMAV | 291 | P49279 | |
| ISFDVIQQASLEDMI | 1756 | Q07864 | |
| VFATRMTADQAIIFV | 206 | A2A3K4 | |
| MADVINVSVNLEAFS | 1 | Q6P2C8 | |
| NVISMEVTNVIFLGV | 196 | Q9NQN1 | |
| RMQIVVILSEFFNTT | 151 | Q86WC4 | |
| MADDNFTVVTEFILL | 1 | Q8NH18 | |
| QTFQAFSEMLQSLVV | 216 | Q9H579 | |
| FSLQETVFAMLVEIT | 231 | Q9NPF4 | |
| QSRFDMAENVVIVAS | 3681 | Q7Z6Z7 | |
| MLFIFLVVVEVNSEF | 11 | Q02413 | |
| VENVDVLTQMRTSFD | 871 | Q9Y2A7 | |
| FVNMVLEDVTEFEIT | 46 | Q9Y4Y9 | |
| DVFVLVANSESTLMQ | 221 | O95140 | |
| FQSMEITELEFVQII | 31 | Q969W9 | |
| ITQMYFSIVFVVTDN | 111 | Q8NGQ3 | |
| MVRFASLFNVKDQTV | 481 | P20393 | |
| VTMFILISFTEEFDV | 21 | Q8NG75 | |
| DQVLESVVEFLMNAL | 951 | A4FU69 | |
| IVEFLQSFDEITAMT | 686 | P16615 | |
| VVSDLFTERNQFELM | 2706 | P42858 | |
| VEVFDSFENMRVFLQ | 106 | Q7L8L6 | |
| IETFQTSSELVDFLM | 956 | Q92608 | |
| FDELLQMFTVQEVAE | 796 | Q8IZD9 | |
| QMFTVQEVAEFVRGT | 801 | Q8IZD9 | |
| EISNIVFTSLFALEM | 776 | O43497 | |
| TKMAEAIRNFVNTFI | 421 | Q9Y232 | |
| FLMTDSQVAEEQFLV | 2856 | Q9UFH2 | |
| FATEFINMDGIIVLT | 116 | Q96JJ3 | |
| DILNVAFTIIFTLEM | 1151 | Q13698 | |
| LVINLFVAVIMDNFD | 1371 | Q13698 | |
| VVEFMFQATEGDVLN | 141 | Q14993 | |
| SVSMVDFSIAVENQL | 921 | Q9Y4F1 | |
| VVVETIQMNTIFDGE | 766 | Q6ZTQ4 | |
| MSREVQVFEITENSA | 2991 | P12111 | |
| EFVQEVSEILMAFGI | 406 | Q6IQ26 | |
| EKNVVFVIDVSSSMF | 281 | Q6UXX5 | |
| NRMTFVTEEEGINVF | 71 | Q9NYL5 | |
| EVETFAFQAEIAQLM | 16 | P07900 | |
| LFSFMVLALNVVTVA | 571 | Q86UP6 | |
| VTSDVLLQEMVFFIL | 421 | Q5W0V3 | |
| VVVFNSVFNMESFLT | 121 | Q4AE62 | |
| VLASMAFVVAAIVQV | 366 | P46059 | |
| VFNVVSDTFFLMDLV | 246 | Q9UL51 | |
| EVETFAFQAEIAQLM | 16 | Q14568 | |
| FANMELSEVVSNTIL | 266 | Q96JN8 | |
| VDVTEVVRNMTSEFF | 336 | P36268 | |
| TSANEMVIFVDIGLV | 191 | Q8NGN4 | |
| DTTMNESELFFVSVI | 191 | P59922 | |
| VTANLVMIFLIQVDS | 36 | Q8NH01 | |
| TAAFMEVRVQSIVVE | 191 | Q7Z6I6 | |
| IMVAADIVTIFNLIQ | 81 | Q9UPX6 | |
| FQEFKQTFTEQMNIV | 4211 | Q685J3 | |
| DMVSSTVFQQILDFI | 86 | Q96JB3 | |
| FGSNEDVIVLSMVII | 541 | Q8N3S3 | |
| VQSFYQQELEMVESL | 221 | Q9H668 | |
| VIATIAFLMINAVSN | 61 | O95807 | |
| NLMNLIATVFVFAVV | 241 | Q9H9S3 | |
| NVNTVSVMINEELFS | 171 | Q99985 | |
| SSLFNEVVQMNFEIA | 376 | Q8N3T6 | |
| EVVQMNFEIASFSSL | 381 | Q8N3T6 | |
| VQQFSILETMTALDF | 126 | P48775 | |
| DVISMNASEFSEVQI | 1316 | Q5JRA6 | |
| VEVLFLEANEQMFAI | 576 | Q587J7 | |
| FQIGRSTENMIDFVV | 151 | Q8N2H9 | |
| AVVYSNTIQSIMAIV | 71 | P04899 | |
| QIFTAIFDMNTDVII | 71 | A1A4F0 | |
| QAAVVVVFNFAMVLL | 576 | Q13635 | |
| IFDIVTKQAFDVTIM | 1521 | Q14524 | |
| SFDEFIQMSVQRIVE | 46 | P30876 | |
| DNIAFMITETTVQVL | 1381 | Q5T5P2 | |
| TFVLYQMQFTQAVEV | 446 | Q03518 | |
| EMVSFNTVVLDSVQD | 561 | Q9NT68 | |
| SLIEQMVVASAVLTF | 191 | A6NDL8 | |
| ELMVSNTTFVNFDLI | 2466 | P08F94 | |
| DFVTRQVFDISIMIL | 1521 | Q9NY46 | |
| NDMVIIVARVLFAVS | 291 | A6NNN8 | |
| ELVVDSQMQSIFTDI | 176 | Q12769 | |
| FVLDFNMKNVTEVTL | 36 | Q8NGG2 | |
| IESEVEQAFITMNLF | 1001 | Q13018 | |
| DFVTRQVFDISIMIL | 1536 | P35498 | |
| RVILFSTQFMDEADI | 666 | O94911 | |
| ISQIVDIFMENSLIQ | 546 | P53675 | |
| TVVQEVIEFFVMVFQ | 651 | Q15021 | |
| VFSMFLETLVDFIQV | 711 | O75122 | |
| FAITIRNQSVSMFVE | 166 | Q17RW2 | |
| VQEFMTFTSQLIVER | 36 | O15498 | |
| AEELFASIATIQMQS | 651 | Q9P2M4 | |
| MISFQESVTFQDVAV | 1 | Q5T5D7 | |
| VLFQAATAIMEAVVR | 66 | Q9C0E2 | |
| RQIFMLTVEVLQEFS | 196 | Q9C0E2 | |
| MVFESVVVDVLNRFL | 1 | Q96RL7 | |
| LDVLFGNLTEMVEFQ | 1081 | Q13009 | |
| VTALDNERFTVQSVM | 266 | Q12767 | |
| NLMNLIATIFVFAVV | 241 | P61619 | |
| LVMEFNELSFQEVIE | 106 | Q8NE28 | |
| SLVVALMQEVFTEFF | 181 | Q9H6E5 | |
| DFNEFVVMVAALTVA | 71 | Q8WXG8 | |
| MEFVTALVNLQEESS | 1 | Q495X7 | |
| MDSVVFEDVAVNFTQ | 1 | Q8N972 | |
| MDLVAFEDVAVNFTQ | 1 | Q08AG5 | |
| MESVTFEDVAVEFIQ | 1 | Q96JL9 | |
| LAIEIFMVSNASSIQ | 1591 | Q8N9V7 | |
| QQEVQSFFVVMALIS | 636 | Q9HBG4 | |
| DVLAVATFLQMQDII | 91 | Q13105 | |
| MLVFVDVENTNTSEA | 1101 | Q9Y2L5 | |
| DVVTSQAFNVIVMVL | 1246 | Q01118 | |
| VSMAINEVFNELILD | 196 | Q9UH65 | |
| LNSLIQVFVMNVDFT | 66 | Q9UMW8 | |
| DFILQAERETFIEQM | 1236 | Q9Y3S1 | |
| QEELAFVFEMLQQFE | 226 | P48553 | |
| FVFEMLQQFEDALVQ | 231 | P48553 | |
| VSRQTLFEDSFQQIM | 571 | Q9H0M0 | |
| FRNVKITDESLFQVM | 256 | O60603 | |
| MIQSQISFEDVAVDF | 1 | Q86T29 | |
| VMFRFLETENEENVL | 116 | Q9Y4A5 | |
| MATNIEQIFRSFVVS | 1 | P18583 | |
| FQDVTFTMGQVVSRE | 171 | O75888 | |
| VIEMQGFATVLAEAV | 41 | Q6NUM6 | |
| KVITMFVQRQVFAEN | 36 | P13010 | |
| QMDLVTFDSVAVEFT | 106 | Q96MR9 | |
| VELVQFLNMRDQFFT | 31 | Q6IPR3 | |
| QELETMAAISNTVQF | 51 | Q309B1 | |
| VDVTEVVRNMTSEFF | 336 | P19440 | |
| MAAETLLQQDFELVV | 281 | P48048 | |
| IIETFAEIRVQFQQM | 321 | Q8IZF0 | |
| TANLAAFMIQEEFVD | 646 | Q12879 | |
| AFMIQEEFVDQVTGL | 651 | Q12879 |