Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyCellularComponentinner kinetochore

ORC2 CENPN

3.12e-052092GO:0000939
GeneOntologyCellularComponentkinetochore

ORC2 CENPN

2.58e-0318192GO:0000776
GeneOntologyCellularComponentcondensed chromosome, centromeric region

ORC2 CENPN

2.93e-0319392GO:0000779
GeneOntologyCellularComponentchromosome, centromeric region

ORC2 CENPN

5.88e-0327692GO:0000775
HumanPhenoChiari malformation

SON VANGL1

4.37e-0410722HP:0002308
HumanPhenoAplasia/Hypoplasia of the lungs

SON VANGL1

9.81e-0416022HP:0006703
HumanPhenoVertebral segmentation defect

SON VANGL1

1.01e-0316222HP:0003422
HumanPhenoRenal agenesis

SON VANGL1

1.68e-0320922HP:0000104
HumanPhenoAbnormal localization of kidney

SON VANGL1

2.23e-0324122HP:0100542
HumanPhenoAbnormal lung development

SON VANGL1

2.29e-0324422HP:4000059
PathwayREACTOME_RHOF_GTPASE_CYCLE

VANGL1 ARHGAP32

1.72e-044172MM15630
PathwayREACTOME_RHOF_GTPASE_CYCLE

VANGL1 ARHGAP32

1.80e-044272M41821
PathwayREACTOME_RHOD_GTPASE_CYCLE

VANGL1 ARHGAP32

2.88e-045372M41811
PathwayREACTOME_RHOJ_GTPASE_CYCLE

VANGL1 ARHGAP32

3.10e-045572M41815
PathwayREACTOME_RHOQ_GTPASE_CYCLE

VANGL1 ARHGAP32

3.45e-045872MM15602
PathwayREACTOME_RHOQ_GTPASE_CYCLE

VANGL1 ARHGAP32

3.57e-045972M41812
PathwayREACTOME_RHOD_GTPASE_CYCLE

VANGL1 ARHGAP32

4.20e-046472MM15601
PathwayREACTOME_RHOB_GTPASE_CYCLE

VANGL1 ARHGAP32

4.88e-046972MM15596
PathwayREACTOME_RHOB_GTPASE_CYCLE

VANGL1 ARHGAP32

5.02e-047072M41806
PathwayREACTOME_RHOC_GTPASE_CYCLE

VANGL1 ARHGAP32

5.02e-047072MM15597
PathwayREACTOME_RHOG_GTPASE_CYCLE

VANGL1 ARHGAP32

5.17e-047172MM15604
PathwayREACTOME_RHOC_GTPASE_CYCLE

VANGL1 ARHGAP32

5.61e-047472M41807
PathwayREACTOME_RHOG_GTPASE_CYCLE

VANGL1 ARHGAP32

5.61e-047472M41814
PathwayREACTOME_RAC2_GTPASE_CYCLE

VANGL1 ARHGAP32

7.75e-048772MM15600
PathwayREACTOME_RAC2_GTPASE_CYCLE

VANGL1 ARHGAP32

7.93e-048872M41810
PathwayREACTOME_RAC3_GTPASE_CYCLE

VANGL1 ARHGAP32

8.85e-049372MM15609
PathwayREACTOME_RAC3_GTPASE_CYCLE

VANGL1 ARHGAP32

9.04e-049472M41818
PathwayREACTOME_RHOA_GTPASE_CYCLE

VANGL1 ARHGAP32

2.05e-0314272MM15576
PathwayREACTOME_RHOA_GTPASE_CYCLE

VANGL1 ARHGAP32

2.25e-0314972M41805
PathwayREACTOME_CDC42_GTPASE_CYCLE

VANGL1 ARHGAP32

2.43e-0315572M41808
PathwayREACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3

VANGL1 ARHGAP32 CENPN

2.96e-0364973MM15690
PathwayREACTOME_RAC1_GTPASE_CYCLE

VANGL1 ARHGAP32

3.09e-0317572MM15599
PathwayREACTOME_RAC1_GTPASE_CYCLE

VANGL1 ARHGAP32

3.41e-0318472M41809
PathwayREACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3

VANGL1 ARHGAP32 CENPN

3.98e-0372073M41838
PathwayREACTOME_CELL_CYCLE_CHECKPOINTS

ORC2 CENPN

7.25e-0327172MM15388
PathwayREACTOME_CELL_CYCLE_CHECKPOINTS

ORC2 CENPN

8.33e-0329172M16647
PathwayREACTOME_RHO_GTPASE_CYCLE

VANGL1 ARHGAP32

1.83e-0243972MM15595
PathwayREACTOME_RHO_GTPASE_CYCLE

VANGL1 ARHGAP32

1.92e-0245072M27078
Pubmed

Annotation and analysis of 10,000 expressed sequence tags from developing mouse eye and adult retina.

SON PAIP1

6.24e-06159214519200
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

SON PAIP1 ARHGAP32

1.49e-044309335044719
ToppCellTCGA-Mesothelium-Primary_Tumor-Mesothelioma-Biphasic-3|TCGA-Mesothelium / Sample_Type by Project: Shred V9

NAALAD2 OLFM3

2.81e-0412792df2854bcb2708ddc13b3ca48c03887380e827790
ToppCellfacs-Aorta-Heart-3m-Endothelial-coronary_vascular_endothelial_cell|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OLFM3 ELFN2

3.03e-0413292dc13b54e38fbda9341972cef11833041f2f2a345
ToppCell390C-Lymphocytic-NK_cells-NK_cell_D2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

ARHGAP32 CENPN

4.02e-0415292595afcfa8b161e291fcaf2afc7336bac9b6fae0f
ToppCellControl-PLT_4|World / Disease Group and Platelet Clusters

VANGL1 ARHGAP32

4.12e-0415492a2a03c5e6759c45aeeedf1e68ecb5a0112ef9a20
ToppCellPND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ORC2 CENPN

4.23e-041569233deda19f06172079ef1dd49fd54d66da1e7fb14
ToppCellLPS-antiTNF-Endothelial-Mes-Like|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

OLFM3 VANGL1

4.34e-041589250df52d64d07178975563abd98ce4fddb9f2f7ef
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

NAALAD2 OLFM3

4.73e-0416592a74751e0ec857aa974bec04ccc747c004a8f6e01
ToppCellLPS-antiTNF-Endothelial-Mes-Like-Gen_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

OLFM3 VANGL1

4.79e-04166923b750d4023a0a09d86113aae5a97d84391f7b482
ToppCell343B-Lymphocytic-NK_cells-Proliferating_NK_cell|343B / Donor, Lineage, Cell class and subclass (all cells)

VANGL1 CENPN

4.96e-041699202fa66a91b8bd2bf971aec4f5ec58318b5bfdf14
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NAALAD2 OLFM3

5.02e-04170921f994b690e881106a5d54b3080ccce6260bc3ac5
ToppCell367C-Lymphocytic-NK_cells-NK_cell_D|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

VANGL1 ARHGAP32

5.08e-0417192943fbca8a6ac04052a2a85aca7b21a3461cd96f7
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4/8-lo-Cycling_T|GI_small-bowel / Manually curated celltypes from each tissue

VANGL1 CENPN

5.26e-0417492e4c8da80eca07e4396f57dad212f76c2eca4c1bd
ToppCell343B-Lymphocytic-NK_cells-Proliferating_NK_cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

VANGL1 CENPN

5.50e-0417892c7e890cd02206c516cf1d7692ea7abc8ce746482
ToppCelldroplet-Lung-LUNG-30m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAALAD2 ARHGAP32

5.56e-0417992bfc226bcf0b93525992344f968268a261d86fcbf
ToppCelldroplet-Lung-LUNG-30m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAALAD2 ARHGAP32

5.56e-041799236ad18f52e175ab636ceaa3be81212fa362c96c1
ToppCell343B-Lymphocytic-NK_cells-Proliferating_NK_cell|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

VANGL1 CENPN

5.75e-0418292b1e66ccd5f33b4801f1cafddf97f5fc0c6dba8d1
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c12-MKI67-TYROBP|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

VANGL1 CENPN

5.81e-041839254782c2e23bbeca5b683aa931393b1118da4aa37
ToppCelldroplet-Lung-30m-Mesenchymal-myofibroblast-pericyte_cell-pericyte|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NAALAD2 ARHGAP32

5.88e-04184927128a2be291544d3df3ed6c80f21ddda8437dcba
ToppCelldroplet-Lung-30m-Mesenchymal-myofibroblast-pericyte_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NAALAD2 ARHGAP32

5.88e-0418492d14238f7b0b55a4c8d7040bea854bd221a66ac30
ToppCelldroplet-Lung-30m-Mesenchymal-myofibroblast|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NAALAD2 ARHGAP32

5.88e-041849255dde9c4eebac2a33788c1ff1d8fe312d150fad4
ToppCelldroplet-Lung-nan-3m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ORC2 ARHGAP32

5.94e-041859264791056cdbb739136dbef08f4b16e2b5427faad
ToppCelldroplet-Lung-nan-3m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ORC2 ARHGAP32

5.94e-04185926a85399cfdb9b89683c874e7f046957f9a601dc2
ToppCell5'-GW_trimst-1-SmallIntestine-Neuronal-neurons_B-Branch_B1_(eMN)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

OLFM3 ELFN2

5.94e-0418592ef996f4cdbc3971c6c0460d13df64b075ab22154
ToppCell5'-GW_trimst-1-SmallIntestine-Neuronal-neurons_B|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

OLFM3 ELFN2

5.94e-0418592d51342a3979bd728a80e04126059a3fd8a0dbe3b
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

OLFM3 ARHGAP32

6.07e-0418792f18628ffc7ff7c762b8339ba8822cf0c3157f469
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

OLFM3 ARHGAP32

6.13e-041889250c1b1d690f0e9443082f2adf4f1b8e9ce4cd337
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

OLFM3 ARHGAP32

6.20e-0418992c3df0e3c50af8f1cfb4d790e668bd7f42b276992
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

OLFM3 ARHGAP32

6.20e-0418992a75226616340045b581d08429d2e123e041dee55
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

OLFM3 ARHGAP32

6.26e-041909249e09cdb843b3d889a06a811aa5affae68b25a75
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

OLFM3 ARHGAP32

6.26e-0419092d594da827e3c16644952b9589cc12b947ce36279
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6|TCGA-Prostate / Sample_Type by Project: Shred V9

SON VANGL1

6.46e-0419392abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Stem-like-NPC-like-NPC-like_Prolif-E|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SON CENPN

6.53e-04194927a66bd7d4fc9c6db861cedd2487f241e406869d1
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

OLFM3 ARHGAP32

6.59e-04195922e1df01bf6e4e98e6cd9fb50926e34c5077b8666
ToppCellPosterior_cortex-Endothelial|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

NAALAD2 VANGL1

6.59e-0419592988e3449691cc228cb55e5e30355136c97b12262
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-1_mon|organoid_Paulsen_bioRxiv / Sample Type, Dataset, Time_group, and Cell type.

OLFM3 CENPN

6.73e-0419792b59369f78bf99a4154a46c331d4dad737d8a5f38
ToppCellControl-PLT_4|Control / Disease Group and Platelet Clusters

VANGL1 ARHGAP32

6.80e-0419892387fd3037fd52e4d4c42de0588767e58af228b59
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-4M-Radial_glial-RGCs_3|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.

OLFM3 CENPN

6.87e-041999279d87e2b0adeff2d33c3b699afe7211fddc4f285
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW12-Stem_cells|GW12 / Sample Type, Dataset, Time_group, and Cell type.

VANGL1 CENPN

6.93e-04200920bba93f1271dac704dddcdea8cb0f84a7ac6f42a
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW12-Stem_cells-Neuroepithelial_cell|GW12 / Sample Type, Dataset, Time_group, and Cell type.

VANGL1 CENPN

6.93e-0420092c9479452ab8c51139522383f745f02171ebbd7e2
ToppCellParenchymal-10x5prime-Stromal-Peri/Epineurial_-NAF_endoneurial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

NAALAD2 ARHGAP32

6.93e-04200928a4c210a3130f7baedf15ecbc0f4903b97da0352
ToppCellNeuronal-Excitatory|Neuronal / cells hierarchy compared to all cells using T-Statistic

OLFM3 ARHGAP32

6.93e-04200924409065bc7aa995354c71e0f9d6f3726cf393d6b
ToppCellmLN-(1)_T_cell-(18)_cycling_gd_T|mLN / shred on region, Cell_type, and subtype

VANGL1 CENPN

6.93e-0420092e8a0a88a8344e80783931115bbe6cd5b62a4c1f7
ToppCellmLN-T_cell-cycling_gd_T|mLN / Region, Cell class and subclass

VANGL1 CENPN

6.93e-04200924efeef51f885ee8f6dd3911a536cc49e3c14da98
DrugPhenoxybenzamine hydrochloride [63-92-3]; Down 200; 11.8uM; PC3; HT_HG-U133A

SON VANGL1 ARHGAP32

3.75e-05177934652_DN
Drugdeferoxamine mesylate salt; Down 200; 100uM; PC3; HG-U133A

SON VANGL1 CENPN

5.16e-0519793460_DN
DiseaseAlzheimer disease, polygenic risk score

OLFM3 PAIP1

1.29e-0258692EFO_0030082, MONDO_0004975

Protein segments in the cluster

PeptideGeneStartEntry
MDTESTYSGYSYYSS

VANGL1

1

Q8TAA9
VHYRYSPYSSSSSSY

ARHGAP32

1646

A7KAX9
YPSGYSSSYTESYED

PAIP1

136

Q9H074
YVVYYSQTPYAFTSS

CENPN

151

Q96H22
VYYSYSTKTSTYEYT

OLFM3

416

Q96PB7
YETTTYSPYTEETSY

ORC2

446

Q13416
SYTDSYTDTYTEAYM

SON

1131

P18583
YYSGYSSSPEYSSES

ELFN2

751

Q5R3F8
YSSYPVYHTIYETFE

NAALAD2

536

Q9Y3Q0