Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionDNA-binding transcription factor activity, RNA polymerase II-specific

ADNP SCRT2 SNAI3 ZNF322 ZNF518A PPARG

2.26e-041412146GO:0000981
GeneOntologyMolecularFunctionRNA polymerase II transcription regulatory region sequence-specific DNA binding

ADNP SCRT2 SNAI3 ZNF322 ZNF518A PPARG

2.71e-041459146GO:0000977
GeneOntologyMolecularFunctionE-box binding

SCRT2 PPARG

8.16e-0461142GO:0070888
GeneOntologyMolecularFunctionDNA-binding transcription repressor activity, RNA polymerase II-specific

SCRT2 SNAI3 PPARG

1.30e-03320143GO:0001227
GeneOntologyMolecularFunctioncopper ion binding

ADNP SNAI3

1.33e-0378142GO:0005507
GeneOntologyMolecularFunctionDNA-binding transcription repressor activity

SCRT2 SNAI3 PPARG

1.37e-03326143GO:0001217
GeneOntologyBiologicalProcessregulation of collagen metabolic process

BMP4 FAP PPARG

1.77e-0577143GO:0010712
GeneOntologyBiologicalProcesscollagen metabolic process

BMP4 FAP PPARG

1.24e-04148143GO:0032963
GeneOntologyBiologicalProcessforebrain regionalization

TTC21B BMP4

1.27e-0425142GO:0021871
GeneOntologyBiologicalProcessnegative regulation of extracellular matrix organization

FAP PPARG

1.38e-0426142GO:1903054
GeneOntologyBiologicalProcessnegative regulation of miRNA transcription

BMP4 PPARG

1.97e-0431142GO:1902894
GeneOntologyBiologicalProcessnegative regulation of miRNA metabolic process

BMP4 PPARG

2.37e-0434142GO:2000629
GeneOntologyBiologicalProcessmonocyte differentiation

BMP4 PPARG

2.51e-0435142GO:0030224
GeneOntologyBiologicalProcesscardiac muscle hypertrophy in response to stress

BMP4 PPARG

3.63e-0442142GO:0014898
GeneOntologyBiologicalProcessmuscle hypertrophy in response to stress

BMP4 PPARG

3.63e-0442142GO:0003299
GeneOntologyBiologicalProcesspositive regulation of SMAD protein signal transduction

BMP4 PPARG

3.80e-0443142GO:0060391
GeneOntologyBiologicalProcesscardiac muscle adaptation

BMP4 PPARG

3.80e-0443142GO:0014887
GeneOntologyBiologicalProcessnegative regulation of vascular associated smooth muscle cell proliferation

BMP4 PPARG

5.78e-0453142GO:1904706
GeneOntologyBiologicalProcessnegative regulation of smooth muscle cell migration

BMP4 PPARG

5.78e-0453142GO:0014912
GeneOntologyBiologicalProcessregulation of oligodendrocyte differentiation

BMP4 PPARG

6.92e-0458142GO:0048713
GeneOntologyBiologicalProcesspositive regulation of miRNA transcription

BMP4 PPARG

7.65e-0461142GO:1902895
GeneOntologyBiologicalProcessregulation of canonical Wnt signaling pathway

TTC21B ADNP SHISA6

8.49e-04285143GO:0060828
GeneOntologyBiologicalProcessregulation of collagen biosynthetic process

BMP4 PPARG

8.68e-0465142GO:0032965
GeneOntologyBiologicalProcessregulation of transporter activity

CACNB2 SHISA6 PPARG

9.75e-04299143GO:0032409
GeneOntologyBiologicalProcesspositive regulation of miRNA metabolic process

BMP4 PPARG

1.09e-0373142GO:2000630
GeneOntologyBiologicalProcessstriated muscle adaptation

BMP4 PPARG

1.09e-0373142GO:0014888
GeneOntologyBiologicalProcesscollagen biosynthetic process

BMP4 PPARG

1.18e-0376142GO:0032964
GeneOntologyBiologicalProcessglial cell differentiation

TTC21B BMP4 PPARG

1.20e-03321143GO:0010001
GeneOntologyBiologicalProcessendothelial cell migration

BMP4 FAP PPARG

1.31e-03331143GO:0043542
GeneOntologyBiologicalProcessregulation of miRNA transcription

BMP4 PPARG

1.41e-0383142GO:1902893
GeneOntologyBiologicalProcessmiRNA transcription

BMP4 PPARG

1.44e-0384142GO:0061614
GeneOntologyBiologicalProcessregulation of extracellular matrix organization

FAP PPARG

1.44e-0384142GO:1903053
GeneOntologyBiologicalProcesscanonical Wnt signaling pathway

TTC21B ADNP SHISA6

1.46e-03344143GO:0060070
GeneOntologyBiologicalProcessregulation of SMAD protein signal transduction

BMP4 PPARG

1.66e-0390142GO:0060390
GeneOntologyBiologicalProcessnegative regulation of smooth muscle cell proliferation

BMP4 PPARG

1.66e-0390142GO:0048662
GeneOntologyBiologicalProcessregulation of Wnt signaling pathway

TTC21B ADNP SHISA6

1.77e-03368143GO:0030111
GeneOntologyBiologicalProcessregulation of miRNA metabolic process

BMP4 PPARG

2.16e-03103142GO:2000628
GeneOntologyBiologicalProcessregulation of glial cell differentiation

BMP4 PPARG

2.20e-03104142GO:0045685
GeneOntologyBiologicalProcessdorsal/ventral pattern formation

TTC21B BMP4

2.33e-03107142GO:0009953
GeneOntologyBiologicalProcesspositive regulation of calcium ion transmembrane transport

BMP4 CACNB2

2.42e-03109142GO:1904427
GeneOntologyBiologicalProcessSMAD protein signal transduction

BMP4 PPARG

2.46e-03110142GO:0060395
GeneOntologyBiologicalProcessregulation of vascular associated smooth muscle cell proliferation

BMP4 PPARG

2.55e-03112142GO:1904705
GeneOntologyBiologicalProcessnegative regulation of extrinsic apoptotic signaling pathway

SCRT2 BMP4

2.59e-03113142GO:2001237
GeneOntologyBiologicalProcesspositive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway

BMP4 PPARG

2.68e-03115142GO:0090100
GeneOntologyBiologicalProcessvascular associated smooth muscle cell proliferation

BMP4 PPARG

2.78e-03117142GO:1990874
GeneOntologyBiologicalProcessepithelial cell migration

BMP4 FAP PPARG

2.80e-03432143GO:0010631
GeneOntologyBiologicalProcessepithelium migration

BMP4 FAP PPARG

2.85e-03435143GO:0090132
GeneOntologyBiologicalProcessgliogenesis

TTC21B BMP4 PPARG

2.85e-03435143GO:0042063
GeneOntologyBiologicalProcessmiRNA metabolic process

BMP4 PPARG

2.87e-03119142GO:0010586
GeneOntologyBiologicalProcesstissue migration

BMP4 FAP PPARG

2.96e-03441143GO:0090130
GeneOntologyBiologicalProcesspositive regulation of canonical Wnt signaling pathway

TTC21B ADNP

2.97e-03121142GO:0090263
Domainzf-C2H2

ADNP SCRT2 SNAI3 ZNF322 ZNF518A

1.05e-04693145PF00096
DomainZnf_C2H2/integrase_DNA-bd

ADNP SCRT2 SNAI3 ZNF322 ZNF518A

1.06e-04694145IPR013087
DomainZINC_FINGER_C2H2_2

ADNP SCRT2 SNAI3 ZNF322 ZNF518A

1.78e-04775145PS50157
DomainZINC_FINGER_C2H2_1

ADNP SCRT2 SNAI3 ZNF322 ZNF518A

1.80e-04777145PS00028
DomainZnf_C2H2-like

ADNP SCRT2 SNAI3 ZNF322 ZNF518A

2.02e-04796145IPR015880
DomainZnf_C2H2

ADNP SCRT2 SNAI3 ZNF322 ZNF518A

2.12e-04805145IPR007087
DomainZnF_C2H2

ADNP SCRT2 SNAI3 ZNF322 ZNF518A

2.16e-04808145SM00355
Domain-

SCRT2 SNAI3 ZNF322

1.29e-026791433.30.160.60
PathwayWP_DIFFERENTIATION_OF_WHITE_AND_BROWN_ADIPOCYTE

BMP4 PPARG

6.31e-052572M39665
PathwayPID_NFAT_TFPATHWAY

DGKA PPARG

2.07e-044572M60
Pubmed

Genome-wide association study reveals genetic risk underlying Parkinson's disease.

BMP4 FAM47E

2.85e-052014219915575
Pubmed

Genome-wide association study of primary tooth eruption identifies pleiotropic loci associated with height and craniofacial distances.

BMP4 CACNB2

2.85e-052014223704328
Pubmed

Kruppel-like factor 5 is required for formation and differentiation of the bladder urothelium.

BMP4 PPARG

4.13e-052414221803035
Pubmed

The utility and predictive value of combinations of low penetrance genes for screening and risk prediction of colorectal cancer.

BMP4 PPARG

7.41e-053214220437058
Pubmed

Nell1-deficient mice have reduced expression of extracellular matrix proteins causing cranial and vertebral defects.

DGKA BMP4 PPARG

7.52e-0521014316537572
Pubmed

Kruppel-like factor 5 controls villus formation and initiation of cytodifferentiation in the embryonic intestinal epithelium.

BMP4 PPARG

9.94e-053714223266329
Pubmed

HOXA5 plays tissue-specific roles in the developing respiratory system.

BMP4 PPARG

1.54e-044614228827394
Pubmed

Sall1 balances self-renewal and differentiation of renal progenitor cells.

FAP PPARG

3.28e-046714224550112
Pubmed

Activity-dependent neuroprotective protein recruits HP1 and CHD4 to control lineage-specifying genes.

ADNP ZNF518A

4.00e-047414229795351
CytobandEnsembl 112 genes in cytogenetic band chr2q24

TTC21B FAP

6.76e-04127142chr2q24
GeneFamilyZinc fingers C2H2-type|SNAG transcriptional repressors

SCRT2 SNAI3

2.14e-05101321259
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

SCRT2 SNAI3 ZNF322 ZNF518A

1.32e-0371813428
ToppCellCerebellum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Cerebellum / BrainAtlas - Mouse McCarroll V32

ADNP SCRT2 SHISA6

1.77e-051671439efb9511a211d0824bb97f82c1a5860c43d2138f
ToppCellCerebellum-Neuronal-Inhibitory|Cerebellum / BrainAtlas - Mouse McCarroll V32

ADNP SCRT2 SHISA6

1.77e-05167143904c613aac3f9919a432b110bb1dcc832b5aec0a
ToppCellControl_saline-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|Control_saline / Treatment groups by lineage, cell group, cell type

BMP4 FAP CACNB2

3.04e-05200143bd8cf33502adea320e91ca2af14e1911d88ad374
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

BMP4 FAP CACNB2

3.04e-0520014358b38f9a484ee94191091a0659ed62ebed2d4a14
ToppCellHippocampus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Cbln1|Hippocampus / BrainAtlas - Mouse McCarroll V32

SNAI3 PPARG

2.15e-04701428d6bdf2e773e894a0db39fdff1fafc2474e03fcf
ToppCellStriatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Drd1-Excitatory_Neuron.Gad1Gad2.Drd1-Nfib_(Amygdala)-|Striatum / BrainAtlas - Mouse McCarroll V32

SNAI3 PPARG

2.94e-04821421ca848a18463b1344e23e3ad1b5d01ae27c00586
ToppCellStriatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Drd1-Excitatory_Neuron.Gad1Gad2.Drd1-Nfib_(Amygdala)|Striatum / BrainAtlas - Mouse McCarroll V32

SNAI3 PPARG

2.94e-0482142ab081620b6113f843fede23da0a18720111ffc7c
ToppCellfacs-Marrow-T-cells-24m-Lymphocytic-immature_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLCN5 SNAI3

3.78e-0493142096a207dfd280b23480bc068a15e6947423620c5
ToppCellfacs-Marrow-T-cells-24m-Lymphocytic-immature_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLCN5 SNAI3

3.78e-04931426977ae7eccb45fbc48960a0945be9ccc7566ca8b
ToppCellPBMC-Mild-Myeloid-cDC-cDC-cDC_2|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

BMP4 SHISA6

4.29e-0499142c8fcfc92bcb0c19dc4aaf4e67d263b936d41d589
ToppCellPBMC-Mild-Myeloid-cDC-cDC-cDC_2|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

BMP4 SHISA6

4.37e-0410014232219094edb6e3c81222d5fcfbf222b7fdc58fa3
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6_IT-L6_IT_VISp_Car3|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

FAP SHISA6

7.83e-041341424ef5f395e321cf04e56560be2502a8aa157682f4
ToppCellfacs-Marrow-B-cells-24m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCRT2 SHISA6

8.42e-0413914227dd36f5ef03fa97f0fdb19fbd259cb60e7962b3
ToppCellfacs-Marrow-B-cells-24m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCRT2 SHISA6

8.42e-041391422a54627947f8c6597c041f4785f8a4e52d0edfba
ToppCellSmart-seq2-tissue-resident_(Smart-seq2)-lymphocytic-T_lymphocytic-regulatory_T_cell|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

SNAI3 CACNB2

9.28e-041461427748277cf2f12e2930d4f5a22247ab9bc266a954
ToppCellCerebellum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb|Cerebellum / BrainAtlas - Mouse McCarroll V32

SCRT2 SHISA6

9.66e-041491426e9ca280a599d96f8956ef26f2a46b9484de5488
ToppCellP28-Mesenchymal-mesenchymal_fibroblast-mesenchymal_progenitor_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CACNB2 SHISA6

1.03e-0315414244d4d99b08216c0901e3bc32743fa0a8b85b5149
ToppCellPBMC-Mild-cDC_6|Mild / Compartment, Disease Groups and Clusters

SNAI3 FAM47E

1.06e-031561423db686849844120b3e376599929d11ad06f0d577
ToppCellE18.5-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SNAI3 PPARG

1.08e-03158142f61ebe3a316e4259387cd9da83707f15e6473cae
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CLCN5 CACNB2

1.10e-03159142c186bf05c61fac348cf41973827cced83fafd58a
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CLCN5 CACNB2

1.11e-0316014203b88dc7ad41c6ae443cab7e77ec666340bf432e
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-stromal_related-ICC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DGKA CACNB2

1.13e-03161142deb10628d258fb813c293f81fb71be8e383dc82a
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-stromal_related|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DGKA CACNB2

1.13e-031611428aaca49b53a551395f4025ac4e535c7b0ce41a49
ToppCelldroplet-Marrow-nan-18m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADNP PPARG

1.13e-031611423f3a2148c8d65e6a06f8d8116a3aa58dda17d618
ToppCellfacs-Liver-Non-hepatocytes-24m-Lymphocytic-T_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DGKA SNAI3

1.14e-0316214215d5d31a75e26bcd41919a00300c68e9f00f0002
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage_4|356C / Donor, Lineage, Cell class and subclass (all cells)

CLCN5 FAM47E

1.14e-031621427d43d59531cbefe3ac94953b7faf7156b2a31441
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-CD4-positive,_alpha-beta_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAP PPARG

1.20e-03166142695298a94d62b8adab083900003ec636fbaae5d9
ToppCellLV-11._Adipocyte|World / Chamber and Cluster_Paper

SHISA6 PPARG

1.20e-031661427e5852891714465c6228c9f955fd511ec79d0e02
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-BM_CD4_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAP PPARG

1.20e-03166142aa2df07eff323ded751ced8938af08223d7f2029
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Myeloid-Dendritic-conventional_dendritic_cell-DC_c1-CLEC9A|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ZNF322 ZNF518A

1.20e-03166142c8fd241088de27c6e741a5dfee3cd770183b6bcb
ToppCellsystemic_lupus_erythematosus-flare-Hematopoietic-Progen-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

DGKA CACNB2

1.21e-03167142b89ebd4906f52b1fe6b6540ec9339284e7caddd2
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast-mesothelial_cell-mesothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FAP SHISA6

1.21e-031671421adb566f98af0109c8cc6e36033b89651e2c75e7
ToppCell5'-GW_trimst-2-LargeIntestine-Hematopoietic-T_cells-SELL+_CD4_T|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DGKA SNAI3

1.21e-03167142484de3ca4a905067c18d06995601479eef8fc15e
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast-mesothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FAP SHISA6

1.21e-03167142743df5908c1ceb43b34b240d9f9649f30f4142fa
ToppCelldroplet-Lung-1m-Hematologic-myeloid-interstitial_macrophage-interstitial_macrophage_l12|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CLCN5 FAP

1.25e-031701420272eb1487c2545d4aa06f5d1cd77f823e1441e9
ToppCelldroplet-Lung-30m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell-CD4-positive,_alpha-beta_T_cell_l9|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DGKA SNAI3

1.25e-03170142d74fbd995a8a37fc237f7147d398357b811d6452
ToppCelldroplet-Lung-1m-Hematologic-myeloid-interstitial_macrophage|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CLCN5 FAP

1.25e-03170142f664c7559e383b37845c123e41a3be316d869ba0
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD8_T-CD8_T_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DGKA SNAI3

1.27e-03171142801893c318f7b1abc8d97bac86a00974f910a71c
ToppCelldroplet-Lung-LUNG-30m-Lymphocytic-CD4-positive,_alpha-beta_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DGKA SNAI3

1.28e-03172142f320813177f246926bfd5862b4e0f9bd828cebab
ToppCelldroplet-Lung-LUNG-30m-Lymphocytic-CD4+_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DGKA SNAI3

1.28e-03172142b3c12a4bb08ce931de6fe800b605f3e43adea0b5
ToppCelldroplet-Lung-LUNG-1m-Myeloid-lung_macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLCN5 FAP

1.30e-0317314269b404e92aad3e6dff67e75466f073f20a71f13f
ToppCellPND28-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

BMP4 CACNB2

1.30e-03173142cbd65dd5b01cc959e3ccbc89330ddd0122296ea3
ToppCelldroplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_28|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TTC21B CACNB2

1.30e-0317314266488d01e03264fb193285470901c9c4182fbae8
ToppCellPND28-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

BMP4 CACNB2

1.30e-03173142f9d6e892d66f9b94e4d5beb9f5dec9b606bc868a
ToppCelldroplet-Lung-LUNG-1m-Myeloid-Interstitial_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLCN5 FAP

1.30e-0317314226bba58f9fb215d1d155504906cd77e8774f6936
ToppCellCTRL-Lymphoid-pDC|Lymphoid / Disease state, Lineage and Cell class

CLCN5 FAP

1.31e-03174142ff4315e9fad198cc323fc987deb8652da137cf98
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW19-Neuronal-Neuron|GW19 / Sample Type, Dataset, Time_group, and Cell type.

TTC21B FAP

1.33e-031751422812ac2ef41d245db544697fb6da1883361c96e8
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

BMP4 SHISA6

1.33e-0317514212f5fd83c7710fc0c77406f765d9cbd133433b8b
ToppCelldroplet-Marrow-BM-1m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DGKA PPARG

1.33e-03175142c1c722db42da9b8a2a46e516ddb83d9be5e2e504
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CLCN5 CACNB2

1.33e-03175142427a7ee92fe16a90625946492062d37aa0f7235b
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CLCN5 SHISA6

1.33e-03175142e5467dacf81f1f913b1719931cf1a7331434a7e7
ToppCellP15-Mesenchymal-mesenchymal_fibroblast-tracheal_fibroblast|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

FAP PPARG

1.33e-03175142085cceb1fc2c4ae2f27e85cea5702defecc2cf44
ToppCell390C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

DGKA PPARG

1.33e-031751426374ab186d7ccf7f6dfb858267edba8962789e15
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CLCN5 CACNB2

1.33e-031751421d8aab491dcc27ea5dbfb6462d18ee280b21a05e
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L3_LINC00507_CTXN3|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DGKA PPARG

1.36e-0317714296d639407f79669f3990138793d157b94273581c
ToppCellRV-11._Adipocyte|World / Chamber and Cluster_Paper

SHISA6 PPARG

1.36e-03177142f0edf04930692418953e4f00a917257804ec0ffd
ToppCelldroplet-Marrow-BM-1m-Lymphocytic-plasma_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAP PPARG

1.36e-0317714226bad614560609d318bfc9c235a698bca4e1c22c
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD8_T|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DGKA SNAI3

1.36e-03177142c840efec4eba746543eac0f48dd688518f0fb5f0
ToppCellRV-11._Adipocyte|RV / Chamber and Cluster_Paper

SHISA6 PPARG

1.37e-03178142278bbea5cf8f0589f71675c7a3d00679391b5253
ToppCellPND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD8_T-CD8_T_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DGKA SNAI3

1.37e-03178142934a2a7b35a23b56e34d4d0ef68c271513ef1fe9
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6-Inh_L1_PAX6_CA4|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SCRT2 SHISA6

1.37e-03178142e86ed30652c2de70f16430f04b78789b87df4af2
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Mesenchymal-ependymal_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAP FAM47E

1.39e-031791429d7e39357b269d30ff1e8007a91f8645f3d80e73
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CACNB2 PPARG

1.39e-03179142e6ae070b4c52ba08167c7d64ea4cfbac0454c1bf
ToppCell390C-Lymphocytic-ILC-ILC-1|390C / Donor, Lineage, Cell class and subclass (all cells)

TTC21B SNAI3

1.39e-03179142e7045e27f0eb88f552b31c04b56d78e5ccd7a36c
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Mesenchymal-Ependyma|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAP FAM47E

1.39e-031791421611e11f5f74432627e2f57a27e352b1e46be618
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CLCN5 SHISA6

1.40e-031801429e09b3dfe344b5d50520711513d389865d73a861
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.4.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SNAI3 PPARG

1.40e-03180142fb8bc639f7f94e7aed9f9d708d5d5c78178533ae
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

FAP CACNB2

1.42e-031811429ede19228ba5c0668a9c06c915510b95585216ef
ToppCellMesenchymal_cells-Adipo-CAR|Mesenchymal_cells / Lineage and Cell class

BMP4 PPARG

1.42e-031811421cfb03eb03a37b036b4eeacec69c9b8163af1ee4
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CACNB2 PPARG

1.42e-0318114230729f0364f719c044712a51453e22dc2c1a232b
ToppCellRA-07._Pericyte|RA / Chamber and Cluster_Paper

SHISA6 PPARG

1.42e-031811428dfb42d096db6c2df9b41303a7199d134d4bff07
ToppCellPND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD8_T|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DGKA SNAI3

1.43e-03182142c7e07570480295e1ad3c5fbbb16b8e4df90c690d
ToppCellpdx-Tumor_cells-T6|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

BMP4 SHISA6

1.43e-031821427b24a4f712e1ae1525e8f1c8ec4e1fc43489cbee
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CLCN5 CACNB2

1.45e-0318314231ab55d5f3639f5964541d5eae23044dbda3356e
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CLCN5 CACNB2

1.47e-03184142e8238fe58f94b4f5700ab7f343fb06ea61e899a9
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ADNP DGKA

1.48e-03185142fcd95bc074e982fc7b8fd48d2e80038b9ea35ebb
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CLCN5 CACNB2

1.48e-03185142898a093757f86be3e18d2ef1f16a71f50ef81dc3
ToppCellfacs-Thymus-nan-3m-Lymphocytic-DN4_thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADNP DGKA

1.48e-03185142d50406a9a5b8d75110ba5985741aa2293950c543
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CLCN5 SHISA6

1.48e-0318514203f64a7132b13a01ba47187e0e15c13ac88f7cb2
ToppCellfacs-Thymus-nan-3m-Lymphocytic-DN4_thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADNP DGKA

1.48e-03185142a2cae8c657e4f4d121476798e424876f7e247973
ToppCelldroplet-Liver-LIVER-NPC-1m-Lymphocytic-NK_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DGKA SNAI3

1.50e-03186142629b19447a63412cf1468160a0fedb5dbe02fd72
ToppCellfacs-Marrow-T-cells-3m-Lymphocytic-BM_CD8_+_CD4_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DGKA SNAI3

1.50e-031861424dce1484653bb266e2305cbb306fb11eaf7892e2
ToppCelldroplet-Liver-LIVER-NPC-1m-Lymphocytic|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DGKA SNAI3

1.50e-031861428df32cde77bb0b3e2f37a9664e7b72ec99697395
ToppCelldroplet-Kidney-KIDNEY-1m-Mesenchymal-fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAP SHISA6

1.50e-0318614294d577dbb6bfacf50632e1fe8af041b35a1e6b23
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

BMP4 FAP

1.50e-031861424d68ee3d32f7ef884faf402ef92b31b0eb4656f1
ToppCelldroplet-Liver-LIVER-NPC-1m-Lymphocytic-NK/T|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DGKA SNAI3

1.50e-03186142fac6e66c6512897f9d388dac7bc80a005d6d0293
ToppCellMesenchymal_cells-Adipo-CAR|World / Lineage and Cell class

BMP4 PPARG

1.50e-031861426ca8ce7ced91d6308b7c056032ffec1b37c974bf
ToppCellfacs-Marrow-T-cells-3m-Lymphocytic-mature_alpha-beta_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DGKA SNAI3

1.50e-03186142e23e1246914e230369a716d0d666b98383bf8512
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CLCN5 CACNB2

1.51e-03187142b93cf4dfe8ffb89348ee7bccc9f284189f7240a2
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CLCN5 CACNB2

1.51e-031871427ea8731288e2a99f45e3958590ee1d76f49ae888
ToppCellTCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Ductal_Carcinoma-6|TCGA-Breast / Sample_Type by Project: Shred V9

FAP SHISA6

1.51e-03187142a96495803ba13fcfadd1d83b3cf5774f3fed0a20
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ADNP DGKA

1.53e-031881422b630b0609d4ac61338d6533cb7893cfe1241e44
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Colon_Adenocarcinoma-7|TCGA-Colorectal / Sample_Type by Project: Shred V9

ADNP FAP

1.53e-0318814214bc73cf79c79c9f208369fd8d498e5b26e0114d
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CACNB2 PPARG

1.53e-03188142e751cff2ac8fbc1487766c1871fcc5d1005286b0
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CLCN5 CACNB2

1.53e-031881422ee64bc73a2251fd9f374be759b442cf4ed0d19e
ToppCell10x5'v1-week_12-13-Mesenchymal_osteo-stroma-chondrocyte|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

BMP4 FAP

1.53e-03188142c9270517e6940e9793586f67f02431210552f278
ToppCell10x3'2.3-week_14-16-Mesenchymal_fibro-stroma-endosteal_fibroblast|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

BMP4 FAP

1.53e-031881420e2d1b21f0a7ee306e7dae16fc8c19d16a467883
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CLCN5 CACNB2

1.53e-031881423cee9916399e2e7580cecbcbb27424a71e7e7ac0
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

BMP4 CACNB2

1.55e-03189142a153b83314cf52808f685296cff8c95af3f4983d
ToppCellwk_08-11-Hematologic_Lymphocytic-T_&_ILC-ILC2|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

SNAI3 PPARG

1.55e-031891429c963f525ae765499b3e3229fead3aef018345ef
Drugpurmorphamine

BMP4 PPARG

5.34e-0518142CID005284329
Drugfisetin; Down 200; 50uM; PC3; HG-U133A

ADNP DGKA PPARG

1.61e-04178143579_DN
Drugchroman

DGKA PPARG

1.83e-0433142CID000136319
Drug17-AAG; Down 200; 1uM; PC3; HT_HG-U133A

CLCN5 DGKA PPARG

2.07e-041941431226_DN
Drug(-)-depudecin; Up 200; 1uM; MCF7; HT_HG-U133A_EA

CLCN5 DGKA PPARG

2.10e-04195143874_UP
DrugCefuroxime sodium salt [56238-63-2]; Up 200; 9uM; PC3; HT_HG-U133A

TTC21B BMP4 CACNB2

2.16e-041971435787_UP
DrugThiocolchicoside [602-41-5]; Up 200; 7uM; PC3; HT_HG-U133A

CLCN5 DGKA BMP4

2.20e-041981435095_UP
Druglysophosphatidic acid

DGKA PPARG

5.50e-0457142ctd:C032881
DrugPhosphorus

BMP4 PPARG

1.08e-0380142ctd:D010758
Drugdiisodecyl phthalate

DGKA PPARG

1.22e-0385142ctd:C042080
Diseasetooth eruption

BMP4 CACNB2

7.85e-0528142GO_0044691
Diseaseeye disease

BMP4 SHISA6

2.05e-0445142EFO_0003966
DiseaseDegenerative polyarthritis

BMP4 PPARG

8.72e-0493142C0029408
DiseaseOsteoarthrosis Deformans

BMP4 PPARG

8.72e-0493142C0086743
DiseaseHypermetropia

DGKA SHISA6

1.07e-03103142HP_0000540
DiseasePolydactyly

TTC21B BMP4

1.38e-03117142C0152427
Diseasehypertension (is_implicated_in)

CACNB2 PPARG

1.47e-03121142DOID:10763 (is_implicated_in)

Protein segments in the cluster

PeptideGeneStartEntry
KRCLRHNRSCCKAYE

TTC21B

1221

Q7Z4L5
ASHFSNKRKKCVRDC

ADNP

801

Q9H2P0
ARKKNKNCRRHSLYV

BMP4

301

P12644
CNKQRSRHKSKDRYC

CACNB2

621

Q08289
RCDRCQKKIRIYHSL

DGKA

281

P23743
CHCFNKYRKNEAKRR

CLCN5

296

P51795
NCRSRCFTKHKNGLK

FAM47E

21

Q6ZV65
KHYRCRQCDKSFALK

SCRT2

266

Q9NQ03
RIHKKSRNKCQYCRF

PPARG

181

P37231
YRFCCKKRHEKLDQR

SHISA6

126

Q6ZSJ9
LQTHSDAKKYRCRRC

SNAI3

256

Q3KNW1
KKCVTCHLRKERCQY

FAP

436

Q12884
YKCNKCEKSYRHRSA

ZNF322

211

Q6U7Q0
VSRNRNCKRKCRDSY

ZNF518A

1271

Q6AHZ1