Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncalcium ion binding

JAG2 SCUBE1 FBN1 FBN2 PROZ SCUBE2 CELSR2 MEGF8 TLL1 JAG1 SLIT1 LRP2 LTBP2 F2 TENM2 SVEP1 NOTCH2

3.54e-097497817GO:0005509
GeneOntologyMolecularFunctionextracellular matrix structural constituent

FBN1 FBN2 LTBP2 TECTA COLQ ZP4 MUC2 MUC6

7.10e-07188788GO:0005201
GeneOntologyMolecularFunctionheparin binding

FBN1 LIPH SLIT1 LGR4 LTBP2 F2 COLQ

1.01e-05192787GO:0008201
GeneOntologyMolecularFunctionsulfur compound binding

FBN1 LIPH SLIT1 LGR4 LTBP2 MCCC1 F2 COLQ

3.77e-05323788GO:1901681
GeneOntologyMolecularFunctionglycosaminoglycan binding

FBN1 LIPH SLIT1 LGR4 LTBP2 F2 COLQ

8.51e-05268787GO:0005539
GeneOntologyMolecularFunctionRoundabout binding

SLIT1 LGR4

9.69e-0412782GO:0048495
GeneOntologyMolecularFunctionextracellular matrix constituent conferring elasticity

FBN1 FBN2

9.69e-0412782GO:0030023
GeneOntologyMolecularFunctionpeptidase activity

USP14 PROZ USP38 AOPEP TLL1 CORIN ADAM2 F2 ADAM12

9.98e-04654789GO:0008233
GeneOntologyMolecularFunctionstructural molecule activity conferring elasticity

FBN1 FBN2

1.33e-0314782GO:0097493
GeneOntologyMolecularFunctionendopeptidase activity

USP14 PROZ TLL1 CORIN ADAM2 F2 ADAM12

1.45e-03430787GO:0004175
GeneOntologyBiologicalProcesstransforming growth factor beta receptor superfamily signaling pathway

BMP6 FBN1 FBN2 MEGF8 ING1 PDPK1 LRP2 KCP LTBP2 NOTCH2 OVOL2

1.15e-064458011GO:0141091
GeneOntologyBiologicalProcessaxon guidance

MEGF8 WNT7B SLIT1 GAS1 LRP2 LGR4 CRPPA TENM2 NOTCH2

1.59e-06285809GO:0007411
GeneOntologyBiologicalProcessneuron projection guidance

MEGF8 WNT7B SLIT1 GAS1 LRP2 LGR4 CRPPA TENM2 NOTCH2

1.64e-06286809GO:0097485
GeneOntologyBiologicalProcesscell surface receptor protein serine/threonine kinase signaling pathway

BMP6 FBN1 FBN2 MEGF8 ING1 PDPK1 LRP2 KCP LTBP2 NOTCH2 OVOL2

2.48e-064828011GO:0007178
GeneOntologyBiologicalProcessregulation of transmembrane receptor protein serine/threonine kinase signaling pathway

BMP6 FBN1 FBN2 ING1 PDPK1 LRP2 KCP NOTCH2 OVOL2

7.90e-06347809GO:0090092
GeneOntologyBiologicalProcesspositive regulation of osteoblast differentiation

BMP6 FBN2 SCUBE2 WNT7B JAG1

2.36e-0588805GO:0045669
GeneOntologyBiologicalProcessanimal organ morphogenesis

JAG2 BMP6 FBN2 SCUBE2 EDAR MEGF8 TENM3 WNT7B JAG1 SLIT1 GAS1 LRP2 LGR4 TECTA NOTCH2 OVOL2

2.45e-0512698016GO:0009887
GeneOntologyBiologicalProcessskeletal system development

JAG2 BMP6 FBN1 FBN2 SCUBE2 MEGF8 ANO6 TLL1 WNT7B GAS1 NOTCH2

2.46e-056158011GO:0001501
GeneOntologyBiologicalProcesscell morphogenesis involved in neuron differentiation

CELSR2 MEGF8 UBE3A WNT7B SLIT1 GAS1 LRP2 LGR4 CRPPA TECTA TENM2 NOTCH2

2.97e-057488012GO:0048667
GeneOntologyBiologicalProcessregulation of smoothened signaling pathway

SCUBE1 SCUBE2 MEGF8 WNT7B GAS1

5.51e-05105805GO:0008589
GeneOntologyBiologicalProcesssequestering of TGFbeta in extracellular matrix

FBN1 FBN2

8.87e-054802GO:0035583
GeneOntologyBiologicalProcesscellular response to growth factor stimulus

BMP6 FBN1 FBN2 MEGF8 ING1 UBE3A PDPK1 LRP2 KCP LTBP2 NOTCH2 OVOL2

1.01e-048508012GO:0071363
GeneOntologyBiologicalProcessBMP signaling pathway

BMP6 FBN1 MEGF8 LRP2 KCP NOTCH2

1.18e-04197806GO:0030509
GeneOntologyBiologicalProcesspositive regulation of ossification

BMP6 FBN2 SCUBE2 ANO6

1.26e-0466804GO:0045778
GeneOntologyBiologicalProcessepithelium development

JAG2 KRT26 BMP6 SCUBE1 EDAR MEGF8 PDPK1 WNT7B JAG1 GAS1 LRP2 LGR4 TECTA MUC2 NOTCH2 OVOL2

1.40e-0414698016GO:0060429
GeneOntologyBiologicalProcessresponse to growth factor

BMP6 FBN1 FBN2 MEGF8 ING1 UBE3A PDPK1 LRP2 KCP LTBP2 NOTCH2 OVOL2

1.45e-048838012GO:0070848
GeneOntologyBiologicalProcesschemoattraction of axon

WNT7B LRP2

1.47e-045802GO:0061642
GeneOntologyBiologicalProcessresponse to BMP

BMP6 FBN1 MEGF8 LRP2 KCP NOTCH2

1.89e-04215806GO:0071772
GeneOntologyBiologicalProcesscellular response to BMP stimulus

BMP6 FBN1 MEGF8 LRP2 KCP NOTCH2

1.89e-04215806GO:0071773
GeneOntologyBiologicalProcessregulation of cellular response to growth factor stimulus

FBN1 FBN2 ING1 PDPK1 LRP2 KCP NOTCH2 OVOL2

1.96e-04412808GO:0090287
GeneOntologyBiologicalProcessnegative regulation of transforming growth factor beta receptor signaling pathway

FBN1 FBN2 ING1 PDPK1 OVOL2

2.00e-04138805GO:0030512
GeneOntologyBiologicalProcessnegative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway

FBN1 FBN2 ING1 PDPK1 LRP2 OVOL2

2.04e-04218806GO:0090101
GeneOntologyBiologicalProcessciliary body morphogenesis

JAG1 NOTCH2

2.21e-046802GO:0061073
GeneOntologyBiologicalProcesspulmonary artery morphogenesis

JAG1 LRP2

2.21e-046802GO:0061156
GeneOntologyBiologicalProcessneuron projection morphogenesis

CELSR2 MEGF8 UBE3A WNT7B SLIT1 GAS1 LRP2 LGR4 CRPPA TENM2 NOTCH2

2.60e-048028011GO:0048812
GeneOntologyBiologicalProcessaorta development

GLA MEGF8 JAG1 LRP2

2.65e-0480804GO:0035904
GeneOntologyBiologicalProcessbone mineralization

BMP6 FBN2 GLA ANO6 LGR4

2.86e-04149805GO:0030282
GeneOntologyBiologicalProcessregulation of binding of sperm to zona pellucida

ZAN ZP4

3.08e-047802GO:2000359
GeneOntologyBiologicalProcessplasma membrane bounded cell projection morphogenesis

CELSR2 MEGF8 UBE3A WNT7B SLIT1 GAS1 LRP2 LGR4 CRPPA TENM2 NOTCH2

3.11e-048198011GO:0120039
GeneOntologyBiologicalProcesscell projection morphogenesis

CELSR2 MEGF8 UBE3A WNT7B SLIT1 GAS1 LRP2 LGR4 CRPPA TENM2 NOTCH2

3.34e-048268011GO:0048858
GeneOntologyBiologicalProcessaxonogenesis

MEGF8 WNT7B SLIT1 GAS1 LRP2 LGR4 CRPPA TENM2 NOTCH2

3.40e-04566809GO:0007409
GeneOntologyBiologicalProcessvasculature development

GLA MEGF8 PLPP3 PDPK1 WNT7B JAG1 LRP2 ANKRD17 ADAM12 SVEP1 NOTCH2 OVOL2

3.41e-049698012GO:0001944
GeneOntologyBiologicalProcessneuron projection development

CELSR2 MEGF8 TENM3 UBE3A OTOGL WNT7B SLIT1 GAS1 LRP2 LGR4 CRPPA TECTA TENM2 NOTCH2

3.88e-0412858014GO:0031175
GeneOntologyBiologicalProcessmaintenance of protein location in extracellular region

FBN1 FBN2

4.10e-048802GO:0071694
GeneOntologyBiologicalProcessembryonic morphogenesis

JAG2 FBN2 MEGF8 PLPP3 WNT7B GAS1 LRP2 TECTA NOTCH2 OVOL2

4.25e-047138010GO:0048598
GeneOntologyBiologicalProcesssensory organ development

JAG2 BMP6 TENM3 OTOGL WNT7B JAG1 GAS1 GNB1 TECTA NOTCH2

5.10e-047308010GO:0007423
GeneOntologyBiologicalProcessepithelial cell differentiation

JAG2 KRT26 BMP6 SCUBE1 PDPK1 WNT7B JAG1 TECTA MUC2 NOTCH2 OVOL2

5.17e-048708011GO:0030855
GeneOntologyBiologicalProcessinner ear receptor cell differentiation

JAG2 OTOGL JAG1 TECTA

5.32e-0496804GO:0060113
GeneOntologyBiologicalProcessactivation of protein kinase activity

FBN1 PDPK1 TNFRSF10B NOTCH2

5.53e-0497804GO:0032147
GeneOntologyBiologicalProcessbone development

BMP6 FBN1 SCUBE2 MEGF8 ANO6 NOTCH2

5.65e-04264806GO:0060348
GeneOntologyBiologicalProcessnegative regulation of smoothened signaling pathway

MEGF8 WNT7B GAS1

5.78e-0442803GO:0045879
GeneOntologyBiologicalProcesskidney development

BMP6 FBN1 WNT7B JAG1 LRP2 LGR4 NOTCH2

6.02e-04372807GO:0001822
GeneOntologyBiologicalProcessenzyme-linked receptor protein signaling pathway

BMP6 FBN1 FBN2 MEGF8 ING1 PDPK1 LRP2 KCP LTBP2 SVEP1 NOTCH2 SLC27A4 OVOL2

6.07e-0411868013GO:0007167
GeneOntologyBiologicalProcesssmoothened signaling pathway

SCUBE1 SCUBE2 MEGF8 WNT7B GAS1

6.13e-04176805GO:0007224
GeneOntologyBiologicalProcessglandular epithelial cell development

BMP6 PDPK1 MUC2

6.20e-0443803GO:0002068
GeneOntologyBiologicalProcessepithelial cell development

BMP6 PDPK1 WNT7B JAG1 MUC2 NOTCH2

6.24e-04269806GO:0002064
GeneOntologyBiologicalProcesscell morphogenesis

CELSR2 MEGF8 UBE3A WNT7B SLIT1 GAS1 LRP2 LGR4 CRPPA TECTA F2 TENM2 NOTCH2

6.46e-0411948013GO:0000902
GeneOntologyBiologicalProcessglomerular epithelial cell development

JAG1 NOTCH2

6.55e-0410802GO:0072310
GeneOntologyBiologicalProcessloop of Henle development

WNT7B JAG1

6.55e-0410802GO:0072070
GeneOntologyBiologicalProcesspodocyte development

JAG1 NOTCH2

6.55e-0410802GO:0072015
GeneOntologyBiologicalProcesspositive regulation of smoothened signaling pathway

SCUBE1 SCUBE2 GAS1

7.09e-0445803GO:0045880
GeneOntologyBiologicalProcesstransforming growth factor beta receptor signaling pathway

FBN1 FBN2 ING1 PDPK1 LTBP2 OVOL2

7.13e-04276806GO:0007179
GeneOntologyBiologicalProcessmechanoreceptor differentiation

JAG2 OTOGL JAG1 TECTA

7.19e-04104804GO:0042490
GeneOntologyBiologicalProcessrenal system development

BMP6 FBN1 WNT7B JAG1 LRP2 LGR4 NOTCH2

7.49e-04386807GO:0072001
GeneOntologyBiologicalProcesssequestering of extracellular ligand from receptor

FBN1 FBN2

7.99e-0411802GO:0035581
GeneOntologyBiologicalProcessaxon development

MEGF8 WNT7B SLIT1 GAS1 LRP2 LGR4 CRPPA TENM2 NOTCH2

8.40e-04642809GO:0061564
GeneOntologyBiologicalProcessnephron tubule development

WNT7B JAG1 LGR4 NOTCH2

8.87e-04110804GO:0072080
GeneOntologyBiologicalProcessblood vessel development

GLA MEGF8 PLPP3 PDPK1 WNT7B JAG1 LRP2 ANKRD17 ADAM12 NOTCH2 OVOL2

8.90e-049298011GO:0001568
GeneOntologyBiologicalProcessregulation of transforming growth factor beta receptor signaling pathway

FBN1 FBN2 ING1 PDPK1 OVOL2

9.07e-04192805GO:0017015
GeneOntologyBiologicalProcessregulation of osteoblast differentiation

BMP6 FBN2 SCUBE2 WNT7B JAG1

9.07e-04192805GO:0045667
GeneOntologyBiologicalProcesspositive regulation of bone mineralization

BMP6 FBN2 ANO6

9.10e-0449803GO:0030501
GeneOntologyBiologicalProcesscell fate determination

JAG2 JAG1 NOTCH2

9.66e-0450803GO:0001709
GeneOntologyBiologicalProcessregulation of cellular response to transforming growth factor beta stimulus

FBN1 FBN2 ING1 PDPK1 OVOL2

9.72e-04195805GO:1903844
GeneOntologyBiologicalProcesscell recognition

ZAN MEGF8 CNTNAP3 ADAM2 ZP4

1.04e-03198805GO:0008037
GeneOntologyBiologicalProcessrenal tubule development

WNT7B JAG1 LGR4 NOTCH2

1.08e-03116804GO:0061326
GeneOntologyBiologicalProcessbinding of sperm to zona pellucida

ZAN ADAM2 ZP4

1.08e-0352803GO:0007339
GeneOntologyBiologicalProcessregulation of osteoclast development

FBN1 NOTCH2

1.13e-0313802GO:2001204
GeneOntologyBiologicalProcessextracellular regulation of signal transduction

FBN1 FBN2

1.13e-0313802GO:1900115
GeneOntologyBiologicalProcessextracellular negative regulation of signal transduction

FBN1 FBN2

1.13e-0313802GO:1900116
GeneOntologyBiologicalProcessosteoblast differentiation

BMP6 FBN2 SCUBE2 WNT7B JAG1 LGR4

1.14e-03302806GO:0001649
GeneOntologyBiologicalProcessbiomineral tissue development

BMP6 FBN2 GLA ANO6 LGR4

1.16e-03203805GO:0031214
GeneOntologyBiologicalProcesscirculatory system development

SCUBE1 FBN1 GLA MEGF8 PLPP3 PDPK1 WNT7B JAG1 LRP2 ANKRD17 ADAM12 SVEP1 NOTCH2 OVOL2

1.21e-0314428014GO:0072359
GeneOntologyBiologicalProcessgenitalia development

BMP6 LRP2 LGR4

1.21e-0354803GO:0048806
GeneOntologyBiologicalProcessneuron development

CELSR2 MEGF8 TENM3 UBE3A OTOGL WNT7B SLIT1 GAS1 LRP2 LGR4 CRPPA TECTA TENM2 NOTCH2

1.38e-0314638014GO:0048666
GeneOntologyBiologicalProcessossification

BMP6 FBN2 GLA SCUBE2 ANO6 WNT7B JAG1 LGR4

1.50e-03562808GO:0001503
GeneOntologyBiologicalProcessnephron epithelium development

WNT7B JAG1 LGR4 NOTCH2

1.55e-03128804GO:0072009
GeneOntologyBiologicalProcessregulation of body fluid levels

SCUBE1 PROZ CELSR2 ANO6 F2 MUC2 SVEP1

1.64e-03442807GO:0050878
GeneOntologyBiologicalProcesspositive regulation of biomineral tissue development

BMP6 FBN2 ANO6

1.64e-0360803GO:0070169
GeneOntologyBiologicalProcessregulation of BMP signaling pathway

FBN1 LRP2 KCP NOTCH2

1.69e-03131804GO:0030510
GeneOntologyBiologicalProcessartery development

GLA MEGF8 JAG1 LRP2

1.79e-03133804GO:0060840
GeneOntologyCellularComponentextracellular matrix

LAMB4 FBN1 FBN2 ZAN OTOGL CRISP3 MUC5B LTBP2 TECTA F2 COLQ ZP4 MUC2 MUC6 SVEP1

2.87e-086568115GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

LAMB4 FBN1 FBN2 ZAN OTOGL CRISP3 MUC5B LTBP2 TECTA F2 COLQ ZP4 MUC2 MUC6 SVEP1

2.99e-086588115GO:0030312
GeneOntologyCellularComponentGolgi lumen

PROZ WNT7B MUC5B F2 MUC2 MUC6

4.13e-06109816GO:0005796
GeneOntologyCellularComponentcell surface

USP14 MFAP3 SCUBE1 SCUBE2 ANO6 WNT7B LRP2 CORIN ADAM2 ABCG2 TNFRSF10B F2 NOTCH2

3.25e-0411118113GO:0009986
GeneOntologyCellularComponentcollagen-containing extracellular matrix

LAMB4 FBN1 FBN2 LTBP2 F2 COLQ ZP4 MUC2

1.03e-03530818GO:0062023
GeneOntologyCellularComponentmicrofibril

FBN1 FBN2

1.13e-0313812GO:0001527
DomainEGF_1

JAG2 LAMB4 SCUBE1 FBN1 FBN2 PROZ SCUBE2 ZAN CELSR2 MEGF8 TENM3 TLL1 JAG1 SLIT1 CNTNAP3 LRP2 ADAM2 LTBP2 ADAM12 TENM2 SVEP1 NOTCH2

2.72e-232557822PS00022
DomainEGF_2

JAG2 LAMB4 SCUBE1 FBN1 FBN2 PROZ SCUBE2 ZAN CELSR2 MEGF8 TENM3 TLL1 JAG1 SLIT1 CNTNAP3 LRP2 ADAM2 LTBP2 ADAM12 TENM2 SVEP1 NOTCH2

6.38e-232657822PS01186
DomainEGF_3

JAG2 SCUBE1 FBN1 FBN2 PROZ SCUBE2 ZAN CELSR2 MEGF8 TENM3 TLL1 JAG1 SLIT1 CNTNAP3 LRP2 ADAM2 LTBP2 ADAM12 TENM2 SVEP1 NOTCH2

1.46e-222357821PS50026
DomainEGF-like_dom

JAG2 SCUBE1 FBN1 FBN2 PROZ SCUBE2 ZAN CELSR2 MEGF8 TENM3 TLL1 JAG1 SLIT1 CNTNAP3 LRP2 LTBP2 TECTA ADAM12 TENM2 SVEP1 NOTCH2

4.99e-222497821IPR000742
DomainEGF-like_CS

JAG2 LAMB4 SCUBE1 FBN1 FBN2 PROZ SCUBE2 ZAN CELSR2 MEGF8 TENM3 TLL1 JAG1 SLIT1 CNTNAP3 LRP2 LTBP2 ADAM12 TENM2 SVEP1 NOTCH2

1.35e-212617821IPR013032
DomainEGF

JAG2 SCUBE1 FBN1 FBN2 PROZ SCUBE2 ZAN CELSR2 MEGF8 TENM3 TLL1 JAG1 SLIT1 CNTNAP3 LRP2 LTBP2 TECTA TENM2 SVEP1 NOTCH2

4.54e-212357820SM00181
DomainEGF_CA

JAG2 SCUBE1 FBN1 FBN2 PROZ SCUBE2 CELSR2 MEGF8 TLL1 JAG1 SLIT1 LRP2 LTBP2 TENM2 SVEP1 NOTCH2

4.88e-201227816SM00179
DomainEGF-like_Ca-bd_dom

JAG2 SCUBE1 FBN1 FBN2 PROZ SCUBE2 CELSR2 MEGF8 TLL1 JAG1 SLIT1 LRP2 LTBP2 TENM2 SVEP1 NOTCH2

6.40e-201247816IPR001881
DomainEGF-type_Asp/Asn_hydroxyl_site

JAG2 SCUBE1 FBN1 FBN2 PROZ SCUBE2 CELSR2 MEGF8 TLL1 JAG1 SLIT1 LRP2 LTBP2 SVEP1 NOTCH2

2.38e-191067815IPR000152
DomainEGF

JAG2 PROZ SCUBE2 ZAN CELSR2 TLL1 JAG1 SLIT1 CNTNAP3 LRP2 LTBP2 TECTA SVEP1 NOTCH2

1.37e-161267814PF00008
DomainEGF_Ca-bd_CS

JAG2 SCUBE1 FBN1 FBN2 SCUBE2 MEGF8 TLL1 JAG1 SLIT1 LRP2 LTBP2 SVEP1 NOTCH2

1.45e-16977813IPR018097
DomainEGF_CA

JAG2 SCUBE1 FBN1 FBN2 SCUBE2 MEGF8 TLL1 JAG1 SLIT1 LRP2 LTBP2 SVEP1 NOTCH2

1.92e-16997813PS01187
DomainASX_HYDROXYL

JAG2 SCUBE1 FBN1 FBN2 PROZ SCUBE2 CELSR2 MEGF8 JAG1 LRP2 LTBP2 SVEP1 NOTCH2

2.20e-161007813PS00010
DomainEGF_CA

JAG2 SCUBE1 FBN1 FBN2 SCUBE2 MEGF8 TLL1 JAG1 LRP2 LTBP2 SVEP1 NOTCH2

1.39e-15867812PF07645
DomainVWC_out

JAG2 ZAN JAG1 KCP MUC5B TECTA MUC2 MUC6

4.66e-1519788SM00215
DomainTIL_dom

ZAN LRP2 KCP MUC5B TECTA MUC2 MUC6

5.64e-1414787IPR002919
DomainGrowth_fac_rcpt_

JAG2 SCUBE1 FBN1 FBN2 SCUBE2 CELSR2 MEGF8 JAG1 SLIT1 LRP2 LTBP2 SVEP1 NOTCH2

8.02e-141567813IPR009030
DomainVWF_dom

JAG2 ZAN JAG1 KCP MUC5B TECTA MUC2 MUC6

6.74e-1242788IPR001007
DomainUnchr_dom_Cys-rich

ZAN KCP MUC5B TECTA MUC2 MUC6

7.31e-1213786IPR014853
DomainC8

ZAN KCP MUC5B TECTA MUC2 MUC6

7.31e-1213786SM00832
DomainhEGF

JAG2 FBN2 CELSR2 JAG1 SLIT1 SVEP1 NOTCH2

1.86e-1128787PF12661
DomainVWD

ZAN KCP MUC5B TECTA MUC2 MUC6

3.38e-1116786SM00216
DomainVWF_type-D

ZAN KCP MUC5B TECTA MUC2 MUC6

3.38e-1116786IPR001846
DomainVWFD

ZAN KCP MUC5B TECTA MUC2 MUC6

3.38e-1116786PS51233
DomainVWD

ZAN KCP MUC5B TECTA MUC2 MUC6

3.38e-1116786PF00094
DomainVWC

JAG2 ZAN JAG1 KCP MUC5B TECTA MUC2

1.91e-1038787SM00214
DomainTIL

ZAN MUC5B TECTA MUC2 MUC6

8.63e-1012785PF01826
DomainC8

ZAN MUC5B TECTA MUC2 MUC6

8.63e-1012785PF08742
DomainEGF_extracell

JAG2 TENM3 JAG1 LRP2 LTBP2 ADAM12 SVEP1

5.44e-0960787IPR013111
DomainEGF_2

JAG2 TENM3 JAG1 LRP2 LTBP2 ADAM12 SVEP1

5.44e-0960787PF07974
DomainVWFC_2

JAG2 ZAN KCP MUC5B TECTA MUC2

1.08e-0838786PS50184
DomaincEGF

SCUBE1 FBN1 FBN2 SCUBE2 LRP2

6.85e-0826785IPR026823
DomaincEGF

SCUBE1 FBN1 FBN2 SCUBE2 LRP2

6.85e-0826785PF12662
DomainVWFC_1

JAG2 ZAN KCP MUC5B MUC2

3.80e-0736785PS01208
DomainCT

SLIT1 MUC5B MUC2 MUC6

1.94e-0622784SM00041
DomainTB

FBN1 FBN2 LTBP2

2.42e-067783PF00683
DomainCys_knot_C

SLIT1 MUC5B MUC2 MUC6

3.33e-0625784IPR006207
DomainCTCK_2

SLIT1 MUC5B MUC2 MUC6

3.33e-0625784PS01225
Domain-

FBN1 FBN2 LTBP2

3.87e-0687833.90.290.10
DomainTB

FBN1 FBN2 LTBP2

5.78e-069783PS51364
DomainTB_dom

FBN1 FBN2 LTBP2

5.78e-069783IPR017878
DomainEphrin_rec_like

SCUBE1 SCUBE2 SVEP1

1.13e-0511783PF07699
DomainEGF_3

SCUBE1 SCUBE2 MEGF8

1.50e-0512783PF12947
DomainEGF_dom

SCUBE1 SCUBE2 MEGF8

1.50e-0512783IPR024731
DomainJagged/Serrate

JAG2 JAG1

1.72e-052782IPR026219
DomainRhs_assc_core

TENM3 TENM2

5.15e-053782IPR022385
DomainTILa

ZAN TECTA

5.15e-053782PF12714
DomainTILa_dom

ZAN TECTA

5.15e-053782IPR025615
DomainFBN

FBN1 FBN2

5.15e-053782IPR011398
DomainCUB

SCUBE1 SCUBE2 MEGF8 TLL1

5.17e-0549784PF00431
DomainCTCK_1

SLIT1 MUC5B MUC2

5.47e-0518783PS01185
DomainCUB

SCUBE1 SCUBE2 MEGF8 TLL1

5.60e-0550784SM00042
Domain-

SCUBE1 SCUBE2 MEGF8 TLL1

6.54e-05527842.60.120.290
DomainCUB

SCUBE1 SCUBE2 MEGF8 TLL1

7.06e-0553784PS01180
DomainCUB_dom

SCUBE1 SCUBE2 MEGF8 TLL1

9.40e-0557784IPR000859
DomainTox-GHH_dom

TENM3 TENM2

1.03e-044782IPR028916
DomainTen_N

TENM3 TENM2

1.03e-044782IPR009471
DomainTen_N

TENM3 TENM2

1.03e-044782PF06484
DomainDSL

JAG2 JAG1

1.03e-044782PF01414
DomainTENEURIN_N

TENM3 TENM2

1.03e-044782PS51361
DomainTox-GHH

TENM3 TENM2

1.03e-044782PF15636
DomainDSL

JAG2 JAG1

1.03e-044782SM00051
DomainEphrin_rec_like

SCUBE1 SCUBE2 SVEP1

1.51e-0425783SM01411
DomainTyr-kin_ephrin_A/B_rcpt-like

SCUBE1 SCUBE2 SVEP1

1.51e-0425783IPR011641
DomainDSL

JAG2 JAG1

1.71e-045782IPR001774
DomainDSL

JAG2 JAG1

1.71e-045782PS51051
DomainNotch_ligand_N

JAG2 JAG1

1.71e-045782IPR011651
DomainGuanine_nucleotide-bd_bsu

GNB4 GNB1

1.71e-045782IPR016346
DomainYD

TENM3 TENM2

1.71e-045782IPR006530
DomainMNNL

JAG2 JAG1

1.71e-045782PF07657
DomainWxxW_domain

MUC5B MUC2

2.55e-046782IPR025155
DomainMucin2_WxxW

MUC5B MUC2

2.55e-046782PF13330
DomainEGF_LAM_2

LAMB4 CELSR2 MEGF8

2.62e-0430783PS50027
DomainEGF_LAM_1

LAMB4 CELSR2 MEGF8

2.62e-0430783PS01248
DomainTNFR/NGFR_Cys_rich_reg

CELSR2 EDAR TNFRSF10B

3.49e-0433783IPR001368
DomainLaminin_EGF

LAMB4 CELSR2 MEGF8

4.17e-0435783PF00053
DomainEGF_Lam

LAMB4 CELSR2 MEGF8

4.17e-0435783SM00180
DomainLAM_G_DOMAIN

CELSR2 SLIT1 CNTNAP3

5.32e-0438783PS50025
DomainLaminin_EGF

LAMB4 CELSR2 MEGF8

5.32e-0438783IPR002049
Domain-

TENM3 LRP2 TENM2

5.75e-04397832.120.10.30
DomainLaminin_G_2

CELSR2 SLIT1 CNTNAP3

6.19e-0440783PF02210
Domain-

CELSR2 SLIT1 CNTNAP3 SVEP1

6.72e-04957842.60.120.200
DomainGprotein_B

GNB4 GNB1

7.58e-0410782IPR001632
DomainZP_dom_CS

TECTA ZP4

7.58e-0410782IPR017977
DomainLamG

CELSR2 SLIT1 CNTNAP3

8.20e-0444783SM00282
Domain6-blade_b-propeller_TolB-like

TENM3 LRP2 TENM2

9.35e-0446783IPR011042
Domain-

PROZ F2

1.11e-03127824.10.740.10
DomainCoagulation_fac_subgr_Gla_dom

PROZ F2

1.11e-0312782IPR017857
DomainNHL

TENM3 TENM2

1.30e-0313782PS51125
DomainZP_1

TECTA ZP4

1.52e-0314782PS00682
DomainGla

PROZ F2

1.52e-0314782PF00594
DomainZP_2

TECTA ZP4

1.52e-0314782PS51034
DomainGLA

PROZ F2

1.52e-0314782SM00069
DomainGLA_1

PROZ F2

1.52e-0314782PS00011
DomainGLA_domain

PROZ F2

1.52e-0314782IPR000294
DomainGLA_2

PROZ F2

1.52e-0314782PS50998
DomainZP

TECTA ZP4

1.75e-0315782SM00241
DomainLaminin_G

CELSR2 SLIT1 CNTNAP3

1.83e-0358783IPR001791
DomainDisintegrin_CS

ADAM2 ADAM12

1.99e-0316782IPR018358
DomainConA-like_dom

ZAN CELSR2 SLIT1 CNTNAP3 SVEP1

2.23e-03219785IPR013320
PathwayREACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES

MFAP3 FBN1 FBN2 LTBP2

2.14e-0537634M27134
PathwayKEGG_MEDICUS_REFERENCE_NOTCH_SIGNALING_PATHWAY

JAG2 JAG1 NOTCH2

2.36e-0513633M47423
PathwayREACTOME_ELASTIC_FIBRE_FORMATION

MFAP3 FBN1 FBN2 LTBP2

4.30e-0544634M26969
PathwayREACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS

MUC5B MUC2 MUC6

1.07e-0421633MM15706
PathwayKEGG_HEDGEHOG_SIGNALING_PATHWAY

BMP6 WNT7B GAS1 LRP2

1.12e-0456634M1053
PathwayREACTOME_NOTCH2_ACTIVATION_AND_TRANSMISSION_OF_SIGNAL_TO_THE_NUCLEUS

JAG2 JAG1 NOTCH2

1.23e-0422633M27210
PathwayPID_NOTCH_PATHWAY

JAG2 JAG1 ADAM12 NOTCH2

1.37e-0459634M17
PathwayWP_HYPOTHESIZED_PATHWAYS_IN_PATHOGENESIS_OF_CARDIOVASCULAR_DISEASE

FBN1 FBN2 LTBP2

1.82e-0425633M39713
PathwayREACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PI3KGAMMA

PDPK1 GNB4 GNB1

1.82e-0425633M14301
PathwayREACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PI3KGAMMA

PDPK1 GNB4 GNB1

2.06e-0426633MM15017
PathwayWP_CANONICAL_AND_NONCANONICAL_NOTCH_SIGNALING

JAG2 JAG1 NOTCH2

2.30e-0427633M39545
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

MFAP3 SCUBE1 FBN1 FBN2 TLL1 LTBP2 ADAM12

3.68e-04300637M610
PathwayREACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES

FBN1 FBN2 LTBP2

3.85e-0432633MM14854
PathwayREACTOME_THROMBIN_SIGNALLING_THROUGH_PROTEINASE_ACTIVATED_RECEPTORS_PARS

GNB4 GNB1 F2

3.85e-0432633M861
PathwayREACTOME_G_PROTEIN_BETA_GAMMA_SIGNALLING

PDPK1 GNB4 GNB1

3.85e-0432633M14309
PathwayREACTOME_THROMBIN_SIGNALLING_THROUGH_PROTEINASE_ACTIVATED_RECEPTORS_PARS

GNB4 GNB1 F2

3.85e-0432633MM15148
PathwayREACTOME_SIGNALING_BY_NOTCH1_T_7_9_NOTCH1_M1580_K2555_TRANSLOCATION_MUTANT

JAG2 JAG1

4.07e-047632M27199
PathwayREACTOME_G_PROTEIN_BETA_GAMMA_SIGNALLING

PDPK1 GNB4 GNB1

4.22e-0433633MM15027
PathwayREACTOME_SIGNALING_BY_NOTCH2

JAG2 JAG1 NOTCH2

4.22e-0433633M604
PathwayWP_HAIR_FOLLICLE_DEVELOPMENT_CYTODIFFERENTIATION_STAGE_3_OF_3

BMP6 GAS1 KRTAP15-1 NOTCH2

6.11e-0487634M39465
PathwayREACTOME_ELASTIC_FIBRE_FORMATION

FBN1 FBN2 LTBP2

6.93e-0439633MM14601
PathwayKEGG_MEDICUS_REFERENCE_HEDGEHOG_SIGNALING_PATHWAY_PTCH_CORECEPTOR

GAS1 LRP2

6.93e-049632M47893
PathwayKEGG_MEDICUS_REFERENCE_NOTCH_LIGAND_UBIQUITYLATION

JAG2 JAG1

6.93e-049632M47866
PathwayREACTOME_TRANSPORT_OF_GAMMA_CARBOXYLATED_PROTEIN_PRECURSORS_FROM_THE_ENDOPLASMIC_RETICULUM_TO_THE_GOLGI_APPARATUS

PROZ F2

6.93e-049632MM14614
PathwayREACTOME_GAMMA_CARBOXYLATION_OF_PROTEIN_PRECURSORS

PROZ F2

6.93e-049632MM14613
PathwayREACTOME_REMOVAL_OF_AMINOTERMINAL_PROPEPTIDES_FROM_GAMMA_CARBOXYLATED_PROTEINS

PROZ F2

8.64e-0410632M26977
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

SCUBE1 FBN1 FBN2 TLL1 LTBP2 ADAM12

1.01e-03258636MM14572
PathwayREACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS

PROZ F2

1.05e-0311632M12484
PathwayREACTOME_INTERACTION_WITH_CUMULUS_CELLS_AND_THE_ZONA_PELLUCIDA

ADAM2 ZP4

1.05e-0311632M27184
PathwayREACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS

PROZ F2

1.05e-0311632MM14615
PathwayWP_NOTCH_SIGNALING_WP268

JAG2 JAG1 NOTCH2

1.06e-0345633M39571
PathwayWP_NOTCH_SIGNALING_PATHWAY

JAG2 JAG1 NOTCH2

1.13e-0346633MM15971
PathwayKEGG_NOTCH_SIGNALING_PATHWAY

JAG2 JAG1 NOTCH2

1.20e-0347633M7946
PathwayKEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00380

JAG1 NOTCH2

1.26e-0312632M47532
PathwayWP_VITAMIN_K_METABOLISM_AND_ACTIVATION_OF_DEPENDENT_PROTEINS

PROZ F2

1.49e-0313632M45518
PathwayWP_CANCER_PATHWAYS

JAG2 LAMB4 WNT7B JAG1 GNB4 GNB1 F2 NOTCH2

1.80e-03507638M48302
PathwayWP_OSTEOBLAST_DIFFERENTIATION_AND_RELATED_DISEASES

JAG2 WNT7B JAG1 NOTCH2

1.90e-03118634M39852
PathwayPID_THROMBIN_PAR4_PATHWAY

GNB1 F2

1.99e-0315632M138
PathwayREACTOME_SIGNALING_BY_NOTCH1_HD_DOMAIN_MUTANTS_IN_CANCER

JAG2 JAG1

1.99e-0315632M27202
Pubmed

Notch signaling drives multiple myeloma induced osteoclastogenesis.

JAG2 JAG1 NOTCH2

1.22e-08381325257302
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

JAG2 BMP6 FBN1 FBN2 GLA CELSR2 MEGF8 TENM3 ANO6 TLL1 GAS1 CNTNAP3 LGR4 LTBP2 ADAM12 NOTCH2

1.51e-081201811635696571
Pubmed

Foxp1/4 control epithelial cell fate during lung development and regeneration through regulation of anterior gradient 2.

JAG2 JAG1 MUC5B MUC2 NOTCH2

4.24e-084181522675208
Pubmed

Expression of MUC2, MUC5AC, MUC5B, and MUC6 mucins in colorectal cancers and their association with the CpG island methylator phenotype.

MUC5B MUC2 MUC6

4.86e-08481323807779
Pubmed

Notch pathway regulates female germ cell meiosis progression and early oogenesis events in fetal mouse.

JAG2 JAG1 NOTCH2

4.86e-08481324398584
Pubmed

Epigenetic regulation (DNA methylation, histone modifications) of the 11p15 mucin genes (MUC2, MUC5AC, MUC5B, MUC6) in epithelial cancer cells.

MUC5B MUC2 MUC6

4.86e-08481317471237
Pubmed

The mouse secreted gel-forming mucin gene cluster.

MUC5B MUC2 MUC6

4.86e-08481314984930
Pubmed

Effects of the Helicobacter pylori Virulence Factor CagA and Ammonium Ion on Mucins in AGS Cells.

MUC5B MUC2 MUC6

4.86e-08481329869461
Pubmed

Polymorphisms in MUC1, MUC2, MUC5B and MUC6 genes are not associated with the risk of chronic atrophic gastritis.

MUC5B MUC2 MUC6

4.86e-08481321596555
Pubmed

Characterization of mouse muc6 and evidence of conservation of the gel-forming mucin gene cluster between human and mouse.

MUC5B MUC2 MUC6

4.86e-08481312676567
Pubmed

Comprehensive glycomics comparison between colon cancer cell cultures and tumours: implications for biomarker studies.

MUC5B MUC2 MUC6

1.21e-07581324840470
Pubmed

Functional diversity of notch family genes in fetal lung development.

JAG2 JAG1 NOTCH2

1.21e-07581315064243
Pubmed

Expression of Muc19/Smgc gene products during murine sublingual gland development: cytodifferentiation and maturation of salivary mucous cells.

MUC5B MUC2 MUC6

2.42e-07681319110483
Pubmed

Binding of Delta1, Jagged1, and Jagged2 to Notch2 rapidly induces cleavage, nuclear translocation, and hyperphosphorylation of Notch2.

JAG2 JAG1 NOTCH2

2.42e-07681310958687
Pubmed

Single Cell and Open Chromatin Analysis Reveals Molecular Origin of Epidermal Cells of the Skin.

JAG2 EDAR WNT7B JAG1

3.33e-072581430220568
Pubmed

Expression pattern of notch1, 2 and 3 and Jagged1 and 2 in lymphoid and stromal thymus components: distinct ligand-receptor interactions in intrathymic T cell development.

JAG2 JAG1 NOTCH2

4.23e-07781310383933
Pubmed

Human ligands of the Notch receptor.

JAG2 JAG1 NOTCH2

4.23e-07781310079256
Pubmed

The distribution of Notch receptors and their ligands during articular cartilage development.

JAG2 JAG1 NOTCH2

4.23e-07781312846471
Pubmed

P4 down-regulates Jagged2 and Notch1 expression during primordial folliculogenesis.

JAG2 JAG1 NOTCH2

6.76e-07881322652674
Pubmed

Distinct expression patterns of notch family receptors and ligands during development of the mammalian inner ear.

JAG2 JAG1 NOTCH2

6.76e-0788139858718
Pubmed

Notch/Delta expression in the developing mouse lung.

JAG2 JAG1 NOTCH2

6.76e-07881311044610
Pubmed

p63 regulates multiple signalling pathways required for ectodermal organogenesis and differentiation.

JAG2 EDAR JAG1 NOTCH2

7.14e-073081416524929
Pubmed

Identification of high-molecular-weight proteins with multiple EGF-like motifs by motif-trap screening.

CELSR2 MEGF8 SLIT1

1.01e-0698139693030
Pubmed

Microfibril-associated glycoprotein-2 interacts with fibrillin-1 and fibrillin-2 suggesting a role for MAGP-2 in elastic fiber assembly.

FBN1 FBN2 JAG1

1.01e-06981312122015
Pubmed

Dynamic expression patterns of the pudgy/spondylocostal dysostosis gene Dll3 in the developing nervous system.

JAG2 JAG1 NOTCH2

1.01e-06981311118901
Pubmed

Notch1 signals through Jagged2 to regulate apoptosis in the apical ectodermal ridge of the developing limb bud.

JAG2 JAG1 NOTCH2

1.01e-06981316245338
Pubmed

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.

USP14 KRT26 PROZ GLA MEGF8 ANO6 PSCA LRP2 GNB4 MUC5B LTBP2 GNB1 F2

1.11e-061070811323533145
Pubmed

Deficiency of multidrug resistance 2 contributes to cell transformation through oxidative stress.

JAG2 JAG1 NOTCH2

1.44e-061081326542370
Pubmed

Spatiotemporal expression of Notch receptors and ligands in developing mouse placenta.

JAG2 JAG1 NOTCH2

1.44e-061081323665443
Pubmed

Notch signaling is a novel regulator of visceral smooth muscle cell differentiation in the murine ureter.

JAG2 WNT7B JAG1 COLQ NOTCH2

1.82e-068681535103284
Pubmed

Localisation of members of the notch system and the differentiation of vibrissa hair follicles: receptors, ligands, and fringe modulators.

JAG2 JAG1 NOTCH2

1.98e-061181310878608
Pubmed

Notch-associated gene expression in embryonic and adult taste papillae and taste buds suggests a role in taste cell lineage decisions.

JAG2 JAG1 NOTCH2

1.98e-061181312866128
Pubmed

Developmental expression of the Notch signaling pathway genes during mouse preimplantation development.

JAG2 JAG1 NOTCH2

2.64e-061281315465494
Pubmed

p53 Activity Dominates That of p73 upon Mdm4 Loss in Development and Tumorigenesis.

JAG2 JAG1 NOTCH2

2.64e-061281326527653
Pubmed

Jagged1 is Essential for Radial Glial Maintenance in the Cortical Proliferative Zone.

JAG2 JAG1 NOTCH2

3.42e-061381331202705
Pubmed

Defects in development of the kidney, heart and eye vasculature in mice homozygous for a hypomorphic Notch2 mutation.

JAG2 JAG1 NOTCH2

3.42e-061381311171333
Pubmed

Vascular expression of Notch pathway receptors and ligands is restricted to arterial vessels.

JAG2 JAG1 NOTCH2

3.42e-061381311578869
Pubmed

Math1 controls cerebellar granule cell differentiation by regulating multiple components of the Notch signaling pathway.

JAG2 JAG1 NOTCH2

4.35e-061481314757642
Pubmed

Homo- and heterotypic fibrillin-1 and -2 interactions constitute the basis for the assembly of microfibrils.

FBN1 FBN2

5.36e-06281212399449
Pubmed

Fibrillin-1 and fibrillin-2 are essential for formation of thick oxytalan fibers in human nonpigmented ciliary epithelial cells in vitro.

FBN1 FBN2

5.36e-06281221851253
Pubmed

New Evidence Supporting the Role of FBN1 in the Development of Adolescent Idiopathic Scoliosis.

FBN1 FBN2

5.36e-06281230044367
Pubmed

Material and mechanical properties of bones deficient for fibrillin-1 or fibrillin-2 microfibrils.

FBN1 FBN2

5.36e-06281221440062
Pubmed

MAGP-2 has multiple binding regions on fibrillins and has covalent periodic association with fibrillin-containing microfibrils.

FBN1 FBN2

5.36e-06281215131124
Pubmed

Microfibril structure masks fibrillin-2 in postnatal tissues.

FBN1 FBN2

5.36e-06281220404337
Pubmed

Fibrillln mutations in Marfan syndrome and related phenotypes.

FBN1 FBN2

5.36e-0628128791520
Pubmed

Clinical features, outcomes, and genetic analysis in Korean children with Alagille syndrome.

JAG1 NOTCH2

5.36e-06281225676721
Pubmed

Fibrillin genes map to regions of conserved mouse/human synteny on mouse chromosomes 2 and 18.

FBN1 FBN2

5.36e-0628128307578
Pubmed

Renal involvement and the role of Notch signalling in Alagille syndrome.

JAG1 NOTCH2

5.36e-06281223752887
Pubmed

Notch signaling regulates bile duct morphogenesis in mice.

JAG1 NOTCH2

5.36e-06281218365007
Pubmed

Developmental expression of fibrillin genes suggests heterogeneity of extracellular microfibrils.

FBN1 FBN2

5.36e-0628127744963
Pubmed

A mouse model of Alagille syndrome: Notch2 as a genetic modifier of Jag1 haploinsufficiency.

JAG1 NOTCH2

5.36e-06281211861489
Pubmed

The central exons of the human MUC2 and MUC6 mucins are highly repetitive and variable in sequence between individuals.

MUC2 MUC6

5.36e-06281230504806
Pubmed

Fibrillin microfibrils in bone physiology.

FBN1 FBN2

5.36e-06281226408953
Pubmed

Interaction of vitamin K-dependent protein Z with thrombin. Consequences for the amidolytic activity of thrombin and the interaction of thrombin with phospholipid vesicles.

PROZ F2

5.36e-0628122040612
Pubmed

Arg-Gly-Asp-containing domains of fibrillins-1 and -2 distinctly regulate lung fibroblast migration.

FBN1 FBN2

5.36e-06281218006876
Pubmed

Rare variants in FBN1 and FBN2 are associated with severe adolescent idiopathic scoliosis.

FBN1 FBN2

5.36e-06281224833718
Pubmed

The Notch2-Jagged1 interaction mediates stem cell factor signaling in erythropoiesis.

JAG1 NOTCH2

5.36e-06281220829885
Pubmed

The complete genomic organization of the human MUC6 and MUC2 mucin genes.

MUC2 MUC6

5.36e-06281215081123
Pubmed

Notch signaling in T cells is essential for allergic airway inflammation, but expression of the Notch ligands Jagged 1 and Jagged 2 on dendritic cells is dispensable.

JAG2 JAG1

5.36e-06281228111308
Pubmed

High-fat Diet Alters the Glycosylation Patterns of Duodenal Mucins in a Murine Model.

MUC2 MUC6

5.36e-06281232141795
Pubmed

MUC2 and MUC6 apomucins expression in human gastric neoplasm: an immunohistochemical analysis.

MUC2 MUC6

5.36e-06281220878553
Pubmed

Nonselective assembly of fibrillin 1 and fibrillin 2 in the rodent ocular zonule and in cultured cells: implications for Marfan syndrome.

FBN1 FBN2

5.36e-06281224265020
Pubmed

In vivo studies of mutant fibrillin-1 microfibrils.

FBN1 FBN2

5.36e-06281220529844
Pubmed

Fibrillin-1 mutations causing Weill-Marchesani syndrome and acromicric and geleophysic dysplasias disrupt heparan sulfate interactions.

FBN1 FBN2

5.36e-06281223133647
Pubmed

Members of the Jagged/Notch gene families are expressed in injured arteries and regulate cell phenotype via alterations in cell matrix and cell-cell interaction.

JAG2 JAG1

5.36e-06281211549580
Pubmed

Confocal microscopy demonstrates association of LTBP-2 in fibrillin-1 microfibrils and colocalisation with perlecan in the disc cell pericellular matrix.

FBN1 LTBP2

5.36e-06281224867584
Pubmed

Linkage of Marfan syndrome and a phenotypically related disorder to two different fibrillin genes.

FBN1 FBN2

5.36e-0628121852206
Pubmed

Alagille syndrome mutation update: Comprehensive overview of JAG1 and NOTCH2 mutation frequencies and insight into missense variant classification.

JAG1 NOTCH2

5.36e-06281231343788
Pubmed

Fibrillins can co-assemble in fibrils, but fibrillin fibril composition displays cell-specific differences.

FBN1 FBN2

5.36e-06281212429739
Pubmed

NOTCH ligands JAG1 and JAG2 as critical pro-survival factors in childhood medulloblastoma.

JAG2 JAG1

5.36e-06281224708907
Pubmed

Fibrillin-1 and fibrillin-2 in human embryonic and early fetal development.

FBN1 FBN2

5.36e-06281212524050
Pubmed

Effects of chlorpyrifos exposure on kidney Notch2-Jagged1 pathway of early prenatal embryo.

JAG1 NOTCH2

5.36e-06281221328691
Pubmed

Jag1/2 maintain esophageal homeostasis and suppress foregut tumorigenesis by restricting the basal progenitor cell pool.

JAG2 JAG1

5.36e-06281238750026
Pubmed

Structure and expression of fibrillin-2, a novel microfibrillar component preferentially located in elastic matrices.

FBN1 FBN2

5.36e-0628128120105
Pubmed

The fibrillinopathies: New insights with focus on the paradigm of opposing phenotypes for both FBN1 and FBN2.

FBN1 FBN2

5.36e-06281235419902
Pubmed

Fibrillin assembly: dimer formation mediated by amino-terminal sequences.

FBN1 FBN2

5.36e-06281210504303
Pubmed

Activated NOTCH2 is overexpressed in hepatoblastomas: an immunohistochemical study.

JAG1 NOTCH2

5.36e-06281221639801
Pubmed

Alagille Syndrome

JAG1 NOTCH2

5.36e-06281220301450
Pubmed

Evaluation of the Genetic Association and Expressions of Notch-2 /Jagged-1 in Patients with Type 2 Diabetes Mellitus.

JAG1 NOTCH2

5.36e-06281234219868
Pubmed

Immunohistochemical expression of fibrillin-1 and fibrillin-2 during tooth development.

FBN1 FBN2

5.36e-06281225524144
Pubmed

NOTCH2 participates in Jagged1-induced osteogenic differentiation in human periodontal ligament cells.

JAG1 NOTCH2

5.36e-06281232770090
Pubmed

[Interleukin-1beta induces MUC2/MUC5B gene expression in human nasal epithelial cells].

MUC5B MUC2

5.36e-06281220873538
Pubmed

Interaction of human protein Z with thrombin: evaluation of the species difference in the interaction between bovine and human protein Z and thrombin.

PROZ F2

5.36e-0628121872862
Pubmed

Fibrillins 1 and 2 perform partially overlapping functions during aortic development.

FBN1 FBN2

5.36e-06281216407178
Pubmed

N-terminal domains of fibrillin 1 and fibrillin 2 direct the formation of homodimers: a possible first step in microfibril assembly.

FBN1 FBN2

5.36e-06281210359653
Pubmed

Bile duct proliferation in liver-specific Jag1 conditional knockout mice: effects of gene dosage.

JAG1 NOTCH2

5.36e-06281217366661
Pubmed

Notch signaling in kidney development.

JAG2 NOTCH2

5.36e-06281212496659
Pubmed

Expression of Notch pathway genes in the embryonic mouse metanephros suggests a role in proximal tubule development.

JAG2 JAG1 NOTCH2

5.43e-061581312971992
Pubmed

Lunatic fringe, FGF, and BMP regulate the Notch pathway during epithelial morphogenesis of teeth.

JAG2 JAG1 NOTCH2

5.43e-061581312167404
Pubmed

COUP-TFI controls Notch regulation of hair cell and support cell differentiation.

JAG2 JAG1 NOTCH2

5.43e-061581316914494
Pubmed

Expression of Notch pathway components in fetal and adult mouse small intestine.

JAG2 JAG1 NOTCH2

6.67e-061681312617809
Pubmed

An essential role for Notch in neural crest during cardiovascular development and smooth muscle differentiation.

JAG2 JAG1 NOTCH2

6.67e-061681317273555
Pubmed

The Cellular Prion Protein Controls Notch Signaling in Neural Stem/Progenitor Cells.

JAG2 JAG1 NOTCH2

6.67e-061681327641601
Pubmed

Notch gene expression during pancreatic organogenesis.

JAG2 JAG1 NOTCH2

6.67e-061681310842072
Pubmed

Notch Dosage: Jagged1 Haploinsufficiency Is Associated With Reduced Neuronal Division and Disruption of Periglomerular Interneurons in Mice.

JAG2 JAG1 NOTCH2

6.67e-061681332161758
Pubmed

Gamma-secretase activation of notch signaling regulates the balance of proximal and distal fates in progenitor cells of the developing lung.

JAG2 JAG1 NOTCH2

8.08e-061781318694942
Pubmed

Segmental expression of Notch and Hairy genes in nephrogenesis.

JAG2 JAG1 NOTCH2

8.08e-061781315821257
Pubmed

Mucin gene expression in human laryngeal epithelia: effect of laryngopharyngeal reflux.

MUC5B MUC2 MUC6

9.68e-061881318834073
Pubmed

Lunatic fringe null female mice are infertile due to defects in meiotic maturation.

JAG2 JAG1 NOTCH2

9.68e-061881315659488
Pubmed

Developmental coronary maturation is disturbed by aberrant cardiac vascular endothelial growth factor expression and Notch signalling.

JAG2 JAG1 NOTCH2

9.68e-061881318093989
InteractionNTN5 interactions

JAG2 FBN1 FBN2 LRP2 LGR4 NOTCH2

4.44e-1024816int:NTN5
InteractionMFAP2 interactions

JAG2 FBN1 FBN2 JAG1

1.17e-0712814int:MFAP2
InteractionFBXO2 interactions

JAG2 FBN1 FBN2 MEGF8 TENM3 ANO6 JAG1 CNTNAP3 LRP2 NOTCH2

5.77e-064118110int:FBXO2
InteractionFBN2 interactions

FBN1 FBN2 LTBP2 SVEP1 NOTCH2

6.33e-0665815int:FBN2
InteractionMFAP5 interactions

JAG2 FBN1 FBN2 JAG1

5.66e-0552814int:MFAP5
Cytoband3q27

LIPH MCCC1

8.98e-04258123q27
CytobandEnsembl 112 genes in cytogenetic band chr4p12

GABRG1 CORIN

9.72e-0426812chr4p12
Cytoband22q13

SCUBE1 WNT7B

9.72e-042681222q13
Cytoband11p15.5

MUC5B MUC2 MUC6

1.22e-0311881311p15.5
Cytoband13q34

PROZ ING1

4.15e-035481213q34
Cytoband2q13

EDAR CHCHD5

6.49e-03688122q13
GeneFamilyCD molecules|Mucins

MUC5B MUC2 MUC6

2.56e-0521503648
GeneFamilyGla domain containing

PROZ F2

5.73e-04135021250
GeneFamilyGeneral transcription factors|Xeroderma pigmentosum complementation groups|DNA helicases|ERCC excision repair associated

GTF2H2 GTF3C2

2.16e-0325502565
GeneFamilyADAM metallopeptidase domain containing|CD molecules

ADAM2 ADAM12

2.52e-032750247
GeneFamilyCD molecules|Tumor necrosis factor receptor superfamily|Death inducing signaling complex

EDAR TNFRSF10B

2.90e-0329502782
GeneFamilyUbiquitin specific peptidases

USP14 USP38

1.05e-0256502366
CoexpressionNABA_MATRISOME

LAMB4 BMP6 MFAP3 SCUBE1 FBN1 FBN2 SCUBE2 MEGF8 TLL1 WNT7B SLIT1 KCP MUC5B ADAM2 LTBP2 TECTA F2 COLQ ZP4 ADAM12 MUC2 MUC6 SVEP1

3.68e-1410268123M5889
CoexpressionNABA_MATRISOME

BMP6 MFAP3 SCUBE1 FBN1 FBN2 SCUBE2 MEGF8 OTOGL TLL1 WNT7B SLIT1 KCP MUC5B ADAM2 LTBP2 TECTA F2 COLQ ADAM12 MUC2 MUC6 SVEP1

2.54e-1310088122MM17056
CoexpressionNABA_ECM_GLYCOPROTEINS

LAMB4 MFAP3 FBN1 FBN2 SLIT1 KCP LTBP2 TECTA COLQ ZP4 SVEP1

2.37e-111968111M3008
CoexpressionNABA_ECM_GLYCOPROTEINS

MFAP3 FBN1 FBN2 OTOGL SLIT1 KCP LTBP2 TECTA COLQ SVEP1

4.00e-101918110MM17059
CoexpressionNABA_CORE_MATRISOME

LAMB4 MFAP3 FBN1 FBN2 SLIT1 KCP LTBP2 TECTA COLQ ZP4 SVEP1

8.79e-102758111M5884
CoexpressionNABA_CORE_MATRISOME

MFAP3 FBN1 FBN2 OTOGL SLIT1 KCP LTBP2 TECTA COLQ SVEP1

1.12e-082708110MM17057
CoexpressionNABA_MATRISOME_ASSOCIATED

BMP6 SCUBE1 SCUBE2 MEGF8 TLL1 WNT7B MUC5B ADAM2 F2 ADAM12 MUC2 MUC6

2.71e-067388112MM17058
CoexpressionNABA_MATRISOME_ASSOCIATED

BMP6 SCUBE1 SCUBE2 MEGF8 TLL1 WNT7B MUC5B ADAM2 F2 ADAM12 MUC2 MUC6

3.25e-067518112M5885
CoexpressionFUKUSHIMA_TNFSF11_TARGETS

JAG2 JAG1 NOTCH2

1.55e-0516813MM1296
CoexpressionFUKUSHIMA_TNFSF11_TARGETS

JAG2 JAG1 NOTCH2

1.55e-0516813M2207
CoexpressionFORTSCHEGGER_PHF8_TARGETS_DN

USP14 MFAP3 FBN1 MEGF8 PDPK1 PSCA GNB4 PCMTD2 ABCG2 GNB1 PLEKHM1

2.85e-057838111M2488
CoexpressionNABA_MATRISOME_PRIMARY_METASTATIC_COLORECTAL_TUMOR

MEGF8 LTBP2 F2 SVEP1

3.38e-0559814M47989
CoexpressionMARTINEZ_RB1_TARGETS_DN

MFAP3 FBN2 CELSR2 UBE3A GAS1 LTBP2 KRTAP15-1 TENM2 SLC27A4

6.54e-05569819M12701
CoexpressionMEISSNER_BRAIN_HCP_WITH_H3K4ME3_AND_H3K27ME3

BMP6 SCUBE1 SCUBE2 PLPP3 TLL1 JAG1 GAS1 LRP2 CORIN TNFRSF10B SVEP1 OVOL2

1.10e-0410748112M1941
CoexpressionMARTINEZ_RB1_AND_TP53_TARGETS_DN

MFAP3 FBN2 CELSR2 UBE3A GAS1 LTBP2 KRTAP15-1 TENM2 SLC27A4

1.11e-04610819M3854
CoexpressionHARALAMBIEVA_PBMC_FLUARIX_AGE_50_74YO_CORR_WITH_28D_MEM_B_CELL_RESPONSE_AT_28DY_POSITIVE

TBXAS1 MFAP3 NADSYN1 FBN1 GLA USP38 PLPP3 JAG1 RASGEF1B LGR4 GNB4 TNFRSF10B PLEKHM1

1.13e-0412508113M41099
CoexpressionMARTINEZ_TP53_TARGETS_DN

MFAP3 FBN2 CELSR2 UBE3A GAS1 LTBP2 KRTAP15-1 TENM2 SLC27A4

1.18e-04615819M8673
CoexpressionHAY_BONE_MARROW_STROMAL

SCUBE1 FBN1 PLPP3 OTOGL TLL1 JAG1 GAS1 LTBP2 TENM2 SVEP1

1.25e-047678110M39209
CoexpressionMARTINEZ_RB1_TARGETS_DN

MFAP3 FBN2 CELSR2 UBE3A GAS1 LTBP2 KRTAP15-1 TENM2 SLC27A4

1.41e-04630819MM1038
CoexpressionLIU_CDX2_TARGETS_UP

JAG1 MUC2 MUC6

1.73e-0435813M16637
CoexpressionMARTINEZ_RB1_AND_TP53_TARGETS_DN

MFAP3 FBN2 CELSR2 UBE3A GAS1 LTBP2 KRTAP15-1 TENM2 SLC27A4

1.79e-04650819MM1042
CoexpressionMARTINEZ_TP53_TARGETS_DN

MFAP3 FBN2 CELSR2 UBE3A GAS1 LTBP2 KRTAP15-1 TENM2 SLC27A4

1.98e-04659819MM1040
CoexpressionVECCHI_GASTRIC_CANCER_ADVANCED_VS_EARLY_UP

FBN1 GAS1 GNB4 LTBP2 ADAM12

2.30e-04178815M17079
CoexpressionBRUNEAU_HEART_GREAT_VESSELS_AND_VALVULOGENESIS

JAG1 NOTCH2

2.61e-048812M9884
CoexpressionAtlasdev gonad_e13.5_M_InterstitFLeydig_MafB_top-relative-expression-ranked_500

SCUBE1 FBN1 FBN2 JAG1 RASGEF1B CRPPA ADAM12 SVEP1 NOTCH2

5.60e-06356779gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_500
CoexpressionAtlasdev gonad_e12.5_M_InterstitLeydig_MafB_top-relative-expression-ranked_1000

SCUBE1 FBN1 FBN2 TENM3 JAG1 RASGEF1B LGR4 CRPPA PCMTD2 ADAM12 SVEP1 NOTCH2

1.95e-057687712gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_1000
CoexpressionAtlasdev gonad_e13.5_M_InterstitFLeydig_MafB_top-relative-expression-ranked_1000

SCUBE1 FBN1 FBN2 TENM3 PLPP3 JAG1 RASGEF1B LGR4 CRPPA ADAM12 SVEP1 NOTCH2

2.08e-057737712gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_1000
CoexpressionAtlasEctoderm Differentiated Cells_vs_Endoderm Differentiated Cells-Confounder_removed-fold2.0_adjp0.05

SCUBE1 FBN1 SCUBE2 CELSR2 PLPP3 WNT7B JAG1 GAS1 CNTNAP3 LRP2 LGR4 LTBP2 TNFRSF10B NOTCH2

2.83e-0510757714PCBC_ratio_ECTO_vs_DE_cfr-2X-p05
CoexpressionAtlasStromal Cells, Ep.MEChi.Th, CD45- EpCAm+ Ly51- MHCIIhi, Thymus, avg-2

PLPP3 LIPH LPO PSCA LGR4 GNB4 MCCC1 COLQ

7.54e-05384778GSM777041_500
CoexpressionAtlaskidney_P3_CapMes_Crym_k-means-cluster#4_top-relative-expression-ranked_200

FBN2 TENM3 JAG1 NOTCH2

9.15e-0565774gudmap_kidney_P3_CapMes_Crym_k4_200
CoexpressionAtlasdev gonad_e13.5_M_InterstitTestis_Sma_top-relative-expression-ranked_1000

SCUBE1 FBN1 FBN2 TENM3 JAG1 RASGEF1B LGR4 CRPPA ADAM12 SVEP1 NOTCH2

1.08e-047777711gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_1000
CoexpressionAtlasEctoderm Differentiated Cells_vs_Mesoderm Day 5-Confounder_removed-fold2.0_adjp0.05

SCUBE1 FBN1 SCUBE2 CELSR2 WNT7B JAG1 GAS1 CNTNAP3 LRP2 LTBP2 TNFRSF10B NOTCH2

1.78e-049677712PCBC_ratio_ECTO_vs_MESO-5_cfr-2X-p05
CoexpressionAtlasfacebase_RNAseq_e8.5_ParaxMesoderm_2500_K1

SCUBE1 SLIT1 LRP2

2.11e-0432773facebase_RNAseq_e8.5_ParaxMesoderm_2500_K1
CoexpressionAtlasStromal Cells, FRC.SLN, gp38+ CD31- CD140a+, Lymph Node, avg-4

FBN1 TENM3 PLPP3 JAG1 GAS1 LTBP2 ADAM12 SVEP1

2.41e-04455778GSM777055_500
CoexpressionAtlasplacenta

BMP6 FBN1 FBN2 TENM3 TLL1 ADAM12 SVEP1

2.74e-04349777placenta
CoexpressionAtlasstomach

LIPH PSCA MUC6 ARL14 OVOL2

2.91e-04160775stomach
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN2 TLL1 LRP2 KCP MUC5B TECTA SVEP1

1.76e-08160817c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN2 TLL1 LRP2 KCP MUC5B TECTA SVEP1

1.76e-0816081725c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellmetastatic_Brain-Fibroblasts-Myofibroblasts|metastatic_Brain / Location, Cell class and cell subclass

FBN1 FBN2 TENM3 GAS1 CORIN LTBP2 SVEP1

4.11e-08181817bd0b5f74f9c81ec0f1592710774a4fdf33d9d5a9
ToppCelldroplet-Lung-immune-endo-depleted-3m-Mesenchymal-fibroblast_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN1 SCUBE2 PLPP3 AOPEP GAS1 COLQ SVEP1

5.93e-08191817a261f0738d974784bbdd60f23092bfbcca464459
ToppCelldroplet-Lung-immune-endo-depleted-3m-Mesenchymal-Alveolar_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN1 SCUBE2 PLPP3 AOPEP GAS1 COLQ SVEP1

5.93e-081918176594398cc8151c73696391a43ac110c10283dab1
ToppCell10x5'v1-week_12-13-Mesenchymal_adipo-stroma|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

PLPP3 TLL1 JAG1 GAS1 CNTNAP3 LTBP2 SVEP1

6.37e-08193817cf2461af78f65616ce40d552ee9452295e3895ed
ToppCell10x5'v1-week_12-13-Mesenchymal_adipo|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

PLPP3 TLL1 JAG1 GAS1 CNTNAP3 LTBP2 SVEP1

6.37e-081938176ef9007c9d18fb775d08fb20cdf954a28d54d7eb
ToppCell10x5'v1-week_12-13-Mesenchymal_adipo-stroma-adipo-CAR|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

PLPP3 TLL1 JAG1 GAS1 CNTNAP3 LTBP2 SVEP1

6.37e-08193817e4ea7ce011a80b81b841c907719aa532bed39d2e
ToppCellfacs-Skin-nan-18m-Epithelial-outer_bulge|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCUBE2 TENM3 JAG1 GAS1 LGR4 LTBP2 SVEP1

6.84e-08195817ba7cb80deb872c9184769f0dd57855c3c6a432bf
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_ALM_Cbln4_Fezf2|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SCUBE1 WNT7B RASGEF1B COLQ ADAM12 OVOL2

4.79e-07160816d8241404d775f9a709abdf17988f36293fcf4c58
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GABRG1 NWD2 ZAN OTOGL ADAM2 TECTA

5.16e-07162816bf886e22ff2a20353499004b53f25fb9e6574896
ToppCellP28-Mesenchymal-mesenchymal_fibroblast|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

FBN1 SCUBE2 PLPP3 GAS1 COLQ SVEP1

9.86e-07181816091e7975badd1ffa463a8ec87908be20781ecfd6
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SCUBE1 TENM3 RASGEF1B ADAM12 TENM2 OVOL2

1.16e-0618681656c139e679d640ea901ead657a8e8887e0fca098
ToppCelldroplet-Lung-LUNG-1m-Mesenchymal-fibroblast_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN1 SCUBE2 PLPP3 AOPEP GAS1 COLQ

1.27e-0618981632e6d6285b258831b965281224ff2aaeecdcb5f5
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FBN1 SCUBE2 TENM3 PLPP3 GAS1 SVEP1

1.27e-06189816e9d5e858e320c6e9913c1ea6a54967d21eda605f
ToppCelldroplet-Lung-LUNG-1m-Mesenchymal-Alveolar_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN1 SCUBE2 PLPP3 AOPEP GAS1 COLQ

1.27e-06189816385ef7bbd76c8047aeecf6542377d4213b5da5db
ToppCelldroplet-Lung-18m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FBN1 SCUBE2 PLPP3 GAS1 COLQ SVEP1

1.35e-0619181636467322096bc766cd777dae3bfb4e65511e492c
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FBN1 SCUBE2 TENM3 PLPP3 GAS1 SVEP1

1.35e-06191816b13229bb7f3713a392271aaf5dbae3edd1b9fe5a
ToppCellE16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal|E16.5-samps / Age Group, Lineage, Cell class and subclass

FBN1 SCUBE2 PLPP3 ADAM12 SVEP1 NOTCH2

1.35e-061918163379d145d34f89150f7b06d1340022cfc6b4a6ce
ToppCelldroplet-Lung-18m-Mesenchymal-fibroblast-alveolar_fibroblast|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FBN1 SCUBE2 PLPP3 GAS1 COLQ SVEP1

1.35e-0619181694795daf05061baa3b72a1b01c9e940af86de044
ToppCelldroplet-Lung-30m-Mesenchymal-fibroblast|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FBN1 SCUBE2 PLPP3 GAS1 COLQ SVEP1

1.35e-06191816cd497abed9e00e4e0becd9dbc036c6e7a60ae791
ToppCelldroplet-Lung-21m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FBN1 SCUBE2 PLPP3 GAS1 COLQ SVEP1

1.35e-06191816c715bbdbbf1482aad45a50a16d5232fd35a9a0bb
ToppCelldroplet-Lung-21m-Mesenchymal-fibroblast-alveolar_fibroblast|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FBN1 SCUBE2 PLPP3 GAS1 COLQ SVEP1

1.35e-06191816243d83cbfcc4996ad087ec6386e559e0b8662004
ToppCelldroplet-Lung-1m-Mesenchymal-fibroblast-alveolar_fibroblast|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FBN1 SCUBE2 AOPEP GAS1 COLQ SVEP1

1.35e-06191816d04e6292fef189b8d8ed0f4b0c310b2b250fd30e
ToppCelldroplet-Lung-1m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FBN1 SCUBE2 AOPEP GAS1 COLQ SVEP1

1.35e-06191816de3e9b704621b26836c2ddc39fa3e840dfb4541b
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FBN1 SCUBE2 TENM3 PLPP3 GAS1 SVEP1

1.39e-06192816df1545670370fb1010c567cd059c2783eab315f7
ToppCelldroplet-Lung-30m-Mesenchymal|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FBN1 SCUBE2 PLPP3 GAS1 COLQ SVEP1

1.39e-061928165d5bec238b196f0b3e727fd94f078d6ae524cb01
ToppCelldroplet-Lung-30m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FBN1 SCUBE2 PLPP3 GAS1 COLQ SVEP1

1.39e-06192816ff4b728a55c2550c806c47e9ae3d057c35df8464
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FBN1 SCUBE2 TENM3 PLPP3 GAS1 SVEP1

1.39e-06192816ee085e04d5dcfb657522484ed20b8c1ddeccfe0c
ToppCelldroplet-Lung-30m-Mesenchymal-fibroblast-alveolar_fibroblast|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FBN1 SCUBE2 PLPP3 GAS1 COLQ SVEP1

1.39e-061928162d3790bd80a7f214b37094121a2a86ff16362569
ToppCellPND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FBN1 FBN2 TENM3 PLPP3 GAS1 LTBP2

1.39e-0619281619b94f254d51b9bda3d9b7c6f85e27ecb58409c8
ToppCellCOVID-19-Heart-Fib_2|Heart / Disease (COVID-19 only), tissue and cell type

FBN1 LGR4 LTBP2 ADAM12 SVEP1 NOTCH2

1.48e-06194816d91c9f2ec47319051fc398320693fddbe8bbd4d6
ToppCellTCGA-Blood_and_Bone_Marrow-Primary_Tumor-Diffuse_large_B-cell_lymphoma-DLBCL-1|TCGA-Blood_and_Bone_Marrow / Sample_Type by Project: Shred V9

TENM3 PLPP3 TLL1 GAS1 LTBP2 ADAM12

1.48e-06194816eaeeb84576270cc3fc59002ba33bff9639bb0b02
ToppCellfacs-Thymus-Thymus_Epithelium|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN1 TENM3 JAG1 GAS1 LRP2 LGR4

1.57e-061968166bc1187dfc4860a4e09032d7ea87ba3d9fe9f363
ToppCellfacs-Thymus-Thymus_Epithelium-18m|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN1 TENM3 JAG1 GAS1 LRP2 LGR4

1.57e-06196816c8c89e469402e11aa2a9561e859b6fd1fb66c39b
ToppCellfacs-Skin-nan-18m-Epithelial-bulge_keratinocyte|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TENM3 JAG1 GAS1 LGR4 LTBP2 TENM2

1.57e-0619681681f9754567bbfa67edd304b9ef7b03e7bd9a3b52
ToppCell10x3'2.3-week_17-19-Mesenchymal_adipo|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

SCUBE1 FBN1 PLPP3 LTBP2 TENM2 SVEP1

1.61e-061978165afddde4e2b5cd55abe11e9b9efae02dbdc3da3a
ToppCell10x3'2.3-week_17-19-Mesenchymal_adipo-stroma-adipo-CAR|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

SCUBE1 FBN1 PLPP3 LTBP2 TENM2 SVEP1

1.61e-061978161baffd087ca194a7355fefbb3bf67befb14fe2de
ToppCell10x3'2.3-week_17-19-Mesenchymal_adipo-stroma|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

SCUBE1 FBN1 PLPP3 LTBP2 TENM2 SVEP1

1.61e-06197816b9745e382baa2725dfcae060701fb53f6c8a31fa
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FBN1 TENM3 PLPP3 ADAM12 SVEP1 NOTCH2

1.66e-06198816a860246bcea847249a78fd2e86ed8e04371060db
ToppCellFibroblasts|World / lung cells shred on cell class, cell subclass, sample id

FBN1 TENM3 SLIT1 GAS1 LTBP2 SVEP1

1.71e-06199816e2b6752fcabd5249a166486ae6796f2c97c1fcaf
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FBN1 PLPP3 GAS1 CORIN LTBP2 SVEP1

1.71e-06199816fb580e9321ddf97c73b2e356cd82523db74a38a2
ToppCellFibroblast|World / shred by cell class for parenchyma

FBN1 PLPP3 SLIT1 GAS1 LTBP2 SVEP1

1.76e-06200816dec9ce1bc2571197003596f32e5f742ede72aa79
ToppCellfacs-Pancreas-Exocrine-24m-Endothelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NWD2 OTOGL CNTNAP3 PSCA LRP2

4.01e-061308158c81853c806e9a0d562e00dc5e00a8fc569a854c
ToppCellfacs-Pancreas-Exocrine-24m-Endothelial-endothelial_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NWD2 OTOGL CNTNAP3 PSCA LRP2

4.01e-061308153041d20fe964d282d95c0312396f26bc93929056
ToppCellfacs-Pancreas-Exocrine-24m-Endothelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NWD2 OTOGL CNTNAP3 PSCA LRP2

4.01e-061308153b6a8eaef593db73c2fad2260b9f1e15950ccb70
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GABRG1 NWD2 OTOGL ADAM2 TECTA

6.83e-0614581596712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L5_IT|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SCUBE1 WNT7B RASGEF1B ADAM12 OVOL2

1.35e-05167815f1ce6e64ebede1f3ef36fe982f46919fd1f814dd
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5-Exc_L5-6_RORB_LINC00320|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NWD2 TLL1 SLIT1 RASGEF1B MUC2

1.35e-05167815b0b2601c41c053b1caa6701ba2f5723e6059fb0a
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZAN OTOGL LRP2 TMOD4 LTBP2

1.43e-0516981512bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L5_IT|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SCUBE1 WNT7B RASGEF1B COLQ ADAM12

1.47e-0517081567415b098e8ba815b501e557192a9f2b10ee995a
ToppCell3'-GW_trimst-1.5-LargeIntestine-Epithelial-goblet-Goblet_cell|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LIPH MUC5B MUC2 ARL14 OVOL2

1.47e-051708152c5a1469e5743870e96e6c2cc92f0c5096b79f51
ToppCell3'-GW_trimst-1.5-LargeIntestine-Epithelial-goblet|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LIPH MUC5B MUC2 ARL14 OVOL2

1.47e-051708159bea81031cdfe45e8cddac3a3afd9ca6c331c45a
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NWD2 OTOGL KCP ADAM12 NOTCH2

1.47e-051708155570c0e825bca77613bf0ebde620cf744fa1cb84
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FBN1 PLPP3 GAS1 TECTA SVEP1

1.56e-05172815e37c0b5b547a7345179ab258dd2141fec7064c17
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6_IT|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

TENM3 AOPEP RASGEF1B GNB4 OVOL2

1.70e-05175815c227fc5d1ccb69b82a96a6354913cafaf27d0eec
ToppCellwk_20-22-Endothelial-Blood_vessel_endothelial-OMD+_endo|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

JAG2 BMP6 FBN2 JAG1 CNTNAP3

1.74e-0517681552af8f717dbd3b59eeb868b8b7b256a8f3e57d7a
ToppCellfacs-Skin-Skin_Anagen-18m-Epithelial-inner_bulge|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GABRG1 SCUBE1 SCUBE2 TENM3 LGR4

1.89e-05179815142457c98656ed389461e081e0e6d03e86d2fb1a
ToppCell-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

FBN1 SLIT1 GAS1 LTBP2 SVEP1

1.89e-0517981510fadbaa1b6d21cbf9f354d717cc4c225619f4fd
ToppCellfacs-Pancreas-Exocrine-24m|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OTOGL CNTNAP3 PSCA LRP2 SYCN

1.94e-0518081572310baeed848f2c483ae986cd73d2fb2cca7feb
ToppCellP28-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

FBN1 SCUBE2 PLPP3 COLQ SVEP1

2.05e-0518281519c5e3a9d9b3728303b682102e276adfe93aa759
ToppCell5'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

JAG2 FBN1 ZAN TLL1 CNTNAP3

2.05e-05182815d0e3663f7d39f22a3ebd7fde56ab3504773598f4
ToppCellP28-Mesenchymal|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

FBN1 SCUBE2 PLPP3 GAS1 SVEP1

2.05e-0518281569f9d44694fe4f55a971ae0ac5dc3e7448ee78f3
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN2 ZAN OTOGL LRP2 MUC5B

2.16e-051848152cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN2 ZAN OTOGL LRP2 MUC5B

2.16e-05184815ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN2 ZAN OTOGL LRP2 MUC5B

2.16e-051848152b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

FBN1 FBN2 TENM3 LTBP2 TENM2

2.21e-051858157dcdc009c5681ee05dd18968f7e85c3403fe34af
ToppCellCOVID-19-Heart-Fib_2|COVID-19 / Disease (COVID-19 only), tissue and cell type

FBN1 GAS1 LGR4 LTBP2 SVEP1

2.21e-051858158f95d8e591bf7379d13f5a0545b0cb49e2b1ab5d
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

TBXAS1 FBN1 FBN2 TENM3 GAS1

2.27e-051868154d68ee3d32f7ef884faf402ef92b31b0eb4656f1
ToppCellfacs-Heart-LA-24m-Myeloid-macrophage|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NADSYN1 ZAN LIPH TENM2 SYCN

2.27e-05186815246503fd4e6ae24041c606b069eb5fb313e60f73
ToppCellfacs-Heart-LA-24m-Myeloid-macrophage|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NADSYN1 ZAN LIPH TENM2 SYCN

2.27e-05186815ef93ac469eb4f63db036f14b442c1503b8c6de38
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

FBN1 FBN2 TENM3 LTBP2 TENM2

2.33e-051878155258674d0346e5c51a4b965efcdc1790c970845d
ToppCellLA-01._Fibroblast_I|World / Chamber and Cluster_Paper

FBN1 LIPH LGR4 LTBP2 SVEP1

2.33e-051878154ea486991f66c29728d127171a07b81404ec0b78
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

TBXAS1 BMP6 EDAR LGR4 LTBP2

2.33e-05187815387cb27c8a20031cd87381a9e1172f1f62e1488b
ToppCelldroplet-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN1 FBN2 GAS1 LRP2 SVEP1

2.33e-051878154e553721fa5598cb211f44e3226280b7e6885484
ToppCelldroplet-Pancreas-Exocrine-18m-Mesenchymal|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN1 FBN2 GAS1 LRP2 SVEP1

2.33e-05187815d36e7fc6125e7a4310499365022d38f34b757a73
ToppCelldroplet-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN1 FBN2 GAS1 LRP2 SVEP1

2.33e-05187815827eae63fabf6892a82ce7779b5f395958d3d628
ToppCelldroplet-Lung-LUNG-30m-Mesenchymal|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCUBE2 PLPP3 GAS1 LTBP2 COLQ

2.33e-05187815976b74d081b7fba8620768613cc26f9262cd7b16
ToppCellFibroblast-C|World / shred on cell class and cell subclass (v4)

FBN1 FBN2 TENM3 GAS1 LTBP2

2.45e-0518981558e0400fbab5a0755504275aef5cf7986149abab
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FBN1 SCUBE2 TENM3 GAS1 SVEP1

2.45e-05189815a153b83314cf52808f685296cff8c95af3f4983d
ToppCellfacs-Lung-18m-Mesenchymal|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FBN1 SCUBE2 PLPP3 GAS1 SVEP1

2.45e-05189815bdf8db938aa0863c4fed6fa99dcffd63c8c20c31
ToppCellfacs-Lung-18m-Mesenchymal-fibroblast|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FBN1 SCUBE2 PLPP3 GAS1 SVEP1

2.45e-0518981540cbd679dc0548bf5207e1b033c0597886ad6fe1
ToppCellfacs-Lung-EPCAM-24m-Mesenchymal|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN1 SCUBE2 PLPP3 COLQ SVEP1

2.45e-05189815324c81285c51f4f8bb1aef428b18fe2c549c2c11
ToppCelldroplet-Lung-18m-Mesenchymal-fibroblast|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FBN1 SCUBE2 PLPP3 GAS1 SVEP1

2.45e-05189815e76dc36a01d8ad7590b3acc4c46abfcb76857448
ToppCellfacs-Lung-EPCAM-24m-Mesenchymal-fibroblast_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN1 SCUBE2 PLPP3 COLQ SVEP1

2.52e-0519081500fd993675faf53adf985b9316a18c8a33242029
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FBN1 TENM3 PLPP3 SVEP1 NOTCH2

2.52e-051908151121eb607a984c59fbffe7220837fc178745aa55
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FBN1 TENM3 PLPP3 SVEP1 NOTCH2

2.52e-05190815048b581e3f7ea9fc2f87c0532974bba85c7292c2
ToppCellCOVID-19-kidney-AQP1+SLC14A1+EC|kidney / Disease (COVID-19 only), tissue and cell type

JAG2 BMP6 FBN1 JAG1 GNB4

2.52e-051908151519f34d31fe0817184c5865a0bc9f0cb479b1a4
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TENM3 PLPP3 GAS1 ADAM12 SVEP1

2.52e-0519081545df8fee00f8949937863159d7aa042e72748d9b
ToppCelldroplet-Lung-18m-Mesenchymal|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FBN1 SCUBE2 PLPP3 GAS1 SVEP1

2.52e-051908150b7200897b2c389632c9b1ee37e272b811555dbc
ToppCellfacs-Lung-EPCAM-24m-Mesenchymal-Alveolar_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN1 SCUBE2 PLPP3 COLQ SVEP1

2.52e-051908158cda09d761c6b504a744959d587c183f94f1beeb
ToppCellfacs-Lung-24m-Mesenchymal-fibroblast|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FBN1 SCUBE2 PLPP3 GAS1 SVEP1

2.58e-05191815094c9d3270fc1e487ccf10fb4936af5f081f6009
ToppCellControl-Stromal_mesenchymal|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NWD2 PLPP3 CRPPA SVEP1 NOTCH2

2.58e-0519181514057205ddb9b4bbc582d1358d13cf36d979a61b
ToppCelldroplet-Lung-21m-Mesenchymal-fibroblast|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FBN1 SCUBE2 PLPP3 GAS1 SVEP1

2.58e-051918158a73d2df079566fca4cbb5cdb85721c2e87134c8
ToppCellE15.5-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

FBN1 TENM3 PLPP3 GAS1 TENM2

2.58e-05191815053b3664f509baa107feaf90730f80ebf9ac8f14
ToppCellASK440-Mesenchymal|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq

FBN1 PLPP3 GAS1 LTBP2 SVEP1

2.58e-05191815f12959eebb4167e1aa03de05d7711a702c58b3c9
ToppCelldroplet-Lung-1m-Mesenchymal-fibroblast|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FBN1 SCUBE2 PLPP3 GAS1 SVEP1

2.58e-05191815ce80f65bd24b1c4d2152bf45248449e7a1a97e56
ToppCellfacs-Lung-24m-Mesenchymal|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FBN1 SCUBE2 PLPP3 GAS1 SVEP1

2.58e-05191815ba02cbdfda6a94374a6472eb88499059979af472
ToppCellfacs-Lung-24m-Mesenchymal-fibroblast-alveolar_fibroblast|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FBN1 SCUBE2 PLPP3 COLQ SVEP1

2.58e-0519181580484d39f34703a33b9bac09826b7a526e883cab
ToppCellfacs-Lung-24m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FBN1 SCUBE2 PLPP3 COLQ SVEP1

2.58e-051918155c4e4e9de14edfae072a2a2882220a31bebf51b2
Diseasecortical surface area measurement

JAG2 BMP6 SCUBE1 FBN1 FBN2 ZAN USP38 AOPEP TLL1 JAG1 GAS1 RASGEF1B CRPPA ADAM12 TENM2 PLEKHM1 SVEP1

5.24e-0813457717EFO_0010736
DiseaseHepatic ductular hypoplasia

JAG1 NOTCH2

6.72e-062772C2930797
DiseaseSQUAMOUS CELL CARCINOMA, HEAD AND NECK

ING1 TNFRSF10B

6.72e-062772275355
DiseaseAlagille syndrome (is_implicated_in)

JAG1 NOTCH2

6.72e-062772DOID:9245 (is_implicated_in)
DiseaseAlagille Syndrome 2

JAG1 NOTCH2

6.72e-062772C1857761
DiseaseAlagille Syndrome 1

JAG1 NOTCH2

6.72e-062772C1956125
DiseaseSquamous cell carcinoma of the head and neck

ING1 TNFRSF10B

6.72e-062772cv:C1168401
DiseaseAlagille Syndrome

JAG1 NOTCH2

6.72e-062772C0085280
DiseaseArteriohepatic dysplasia

JAG1 NOTCH2

6.72e-062772cv:C0085280
DiseaseWeill-Marchesani syndrome

FBN1 LTBP2

2.01e-053772C0265313
Diseaseconnective tissue disease (implicated_via_orthology)

FBN1 FBN2

2.01e-053772DOID:65 (implicated_via_orthology)
DiseaseWeill-Marchesani Syndrome, Autosomal Dominant

FBN1 LTBP2

2.01e-053772C1869115
DiseaseWeill-Marchesani Syndrome, Autosomal Recessive

FBN1 LTBP2

2.01e-053772C1869114
DiseaseSquamous cell carcinoma of lip

ING1 TNFRSF10B

2.01e-053772C0280302
DiseaseLaryngeal Squamous Cell Carcinoma

ING1 TNFRSF10B

2.01e-053772C0280324
DiseaseSquamous cell carcinoma of the hypopharynx

ING1 TNFRSF10B

2.01e-053772C0280321
Diseasescoliosis (is_implicated_in)

FBN1 FBN2

4.02e-054772DOID:0060249 (is_implicated_in)
DiseaseWeill-Marchesani syndrome

FBN1 LTBP2

4.02e-054772cv:C0265313
DiseaseWeill-Marchesani syndrome (is_implicated_in)

FBN1 LTBP2

4.02e-054772DOID:0050475 (is_implicated_in)
DiseaseSquamous cell carcinoma of oropharynx

ING1 TNFRSF10B

4.02e-054772C0280313
Diseasepulse pressure measurement

TBXAS1 BMP6 FBN1 FBN2 MEGF8 PLPP3 ING1 JAG1 SLIT1 SF3A3 LTBP2 SVEP1 ARL14

5.95e-0513927713EFO_0005763
DiseaseSquamous cell carcinoma of mouth

ING1 TNFRSF10B

6.69e-055772C0585362
Diseasemucinous adenocarcinoma (is_marker_for)

MUC2 MUC6

6.69e-055772DOID:3030 (is_marker_for)
Diseaseamino acid measurement

GABRG1 NBAS SLIT1 CNTNAP3 LRP2 ABCG2 MCCC1 ADAM12 MUC2

6.79e-05678779EFO_0005134
Diseasecoronary artery disease

TBXAS1 SCUBE1 FBN2 CELSR2 PLPP3 ING1 RASGEF1B SF3A3 TMOD4 ABCG2 SVEP1

2.63e-0411947711EFO_0001645
Diseasebody surface area

BMP6 MFAP3 FBN1 FBN2 AOPEP SLIT1 SF3A3 LTBP2

2.73e-04643778EFO_0022196
DiseaseMarfan syndrome (implicated_via_orthology)

BMP6 FBN1

2.98e-0410772DOID:14323 (implicated_via_orthology)
Diseasethrombosis (implicated_via_orthology)

TBXAS1 F2

2.98e-0410772DOID:0060903 (implicated_via_orthology)
Diseasemyocardial infarction

CELSR2 TENM3 PLPP3 RASGEF1B TMOD4 ABCG2

3.12e-04350776EFO_0000612
DiseaseSquamous cell carcinoma of the head and neck

ING1 ABCG2 TNFRSF10B

3.44e-0452773C1168401
Diseasevital capacity

USP14 BMP6 EDAR LRP2 LGR4 LTBP2 MCCC1 GNB1 TENM2 PLEKHM1 SVEP1

3.52e-0412367711EFO_0004312
DiseaseMarfan Syndrome

FBN1 LTBP2

3.64e-0411772C0024796
DiseaseFamilial thoracic aortic aneurysm and aortic dissection

FBN1 FBN2 JAG1

3.64e-0453773C4707243
DiseaseDiffuse Large B-Cell Lymphoma

PDPK1 ABCG2 NOTCH2

4.07e-0455773C0079744
DiseaseMalignant neoplasm of breast

JAG2 TBXAS1 OTOGL PDPK1 TLL1 JAG1 ABCG2 TECTA ADAM12 NOTCH2

4.70e-0410747710C0006142
Diseaseesterified cholesterol measurement, low density lipoprotein cholesterol measurement

CELSR2 ANKRD17

5.99e-0414772EFO_0004611, EFO_0008589
Diseasecortical thickness

JAG2 BMP6 SCUBE1 FBN1 FBN2 JAG1 LGR4 ADAM12 TENM2 PLEKHM1

6.20e-0411137710EFO_0004840
Diseasecholangiocarcinoma (is_marker_for)

MUC5B MUC2 MUC6

6.35e-0464773DOID:4947 (is_marker_for)
Diseasehead and neck squamous cell carcinoma (is_implicated_in)

ING1 TNFRSF10B

6.90e-0415772DOID:5520 (is_implicated_in)
Diseaseresponse to statin, LDL cholesterol change measurement

CELSR2 ABCG2

6.90e-0415772EFO_0007804, GO_0036273
DiseaseEye Abnormalities

JAG1 CRPPA

8.91e-0417772C0015393
DiseaseMoyamoya Disease

GLA JAG1

8.91e-0417772C0026654
DiseaseHereditary Diffuse Gastric Cancer

NBAS ING1 PSCA MUC6 NOTCH2

1.03e-03293775C1708349
DiseaseCOVID-19, mortality

TENM3 RASGEF1B LRP2 LTBP2

1.04e-03170774EFO_0004352, MONDO_0100096
DiseaseStomach Neoplasms

NBAS ING1 PSCA MUC6 NOTCH2

1.09e-03297775C0038356
DiseaseMalignant neoplasm of stomach

NBAS ING1 PSCA MUC6 NOTCH2

1.14e-03300775C0024623
DiseaseGlioblastoma

JAG2 JAG1 NOTCH2

1.17e-0379773C0017636
Diseaseblood urea nitrogen measurement

USP38 LIPH PSCA LRP2 KCP PCMTD2

1.18e-03452776EFO_0004741
Diseasedilated cardiomyopathy (implicated_via_orthology)

JAG2 JAG1 LTBP2

1.21e-0380773DOID:12930 (implicated_via_orthology)
Diseasestroke, coronary artery disease

CELSR2 PLPP3

1.37e-0321772EFO_0000712, EFO_0001645
DiseaseGiant Cell Glioblastoma

JAG2 JAG1 NOTCH2

1.40e-0384773C0334588
Diseasecongenital heart disease (is_implicated_in)

TLL1 JAG1

1.79e-0324772DOID:1682 (is_implicated_in)
DiseaseCarcinoma, Pancreatic Ductal

JAG2 JAG1

1.79e-0324772C0887833
DiseaseAgents acting on the renin-angiotensin system use measurement

FBN2 CELSR2 USP38 PLPP3 SVEP1

1.85e-03335775EFO_0009931
Diseasepre-eclampsia (is_implicated_in)

CORIN F2

1.94e-0325772DOID:10591 (is_implicated_in)
Diseaselarge artery stroke, coronary artery disease

CELSR2 PLPP3

1.94e-0325772EFO_0001645, EFO_0005524
Diseaseintraocular pressure measurement

FBN1 FBN2 TLL1 LTBP2 F2 ADAM12

2.16e-03509776EFO_0004695
Diseaseindole-3-propionate measurement

NBAS SLIT1

2.26e-0327772EFO_0010501
Diseaseurate measurement

USP38 LIPH ANO6 JAG1 LRP2 LGR4 ABCG2 NOTCH2

2.31e-03895778EFO_0004531
DiseaseCalcium channel blocker use measurement

FBN2 USP38 PLPP3 SVEP1

2.37e-03213774EFO_0009930
Diseasecerebral infarction (is_implicated_in)

TBXAS1 F2

2.61e-0329772DOID:3526 (is_implicated_in)

Protein segments in the cluster

PeptideGeneStartEntry
IDSQYYCNCDAGRNE

CNTNAP3

731

Q9BZ76
EECCFYLNQSGLVYD

nan

476

Q9N2K0
YLGYDCTTDKCNDRG

ADAM2

611

Q99965
NPCNYATCTGEEYLV

ABCG2

601

Q9UNQ0
DVDGYCYNGICQTHE

ADAM12

516

O43184
YDCNCAGASELQSYL

C1orf74

56

Q96LT6
GCYCDSLENLADGYK

GLA

171

P06280
GCYCENTDGLVYVVD

ARL14

76

Q8N4G2
EQLDYYARCSQAPGC

AOPEP

201

Q8N6M6
PGYYGDNCTNVCDLN

CELSR2

1821

Q9HCU4
EGESLLCLACSAGYY

ANKRD17

266

O75179
CSLDGLYAFCGQYLN

NWD2

1106

Q9ULI1
SCEYILAQDYCGDNT

MUC5B

916

Q9HC84
YQQCSDYDLEFGTEC

CRPPA

226

A4D126
SYECSLAETEGNYCN

KRT26

326

Q7Z3Y9
GVACFLYGYLNQDNC

ANO6

316

Q4KMQ2
GSNIEGCYNCSQDEY

MUC6

1171

Q6W4X9
QCPLGYTGSYCEEQL

NOTCH2

1136

Q04721
YTGSYCEEQLDECAS

NOTCH2

1141

Q04721
GDLQCTQYCYIDSTP

COLQ

436

Q9Y215
CAYGATCVDEINGYR

JAG2

836

Q9Y219
CGENEYYNQTTGLCQ

EDAR

31

Q9UNE0
ISGLQAEDEADYYCC

IGLV2-23

96

P01705
DCSQYDRVYCGAGVQ

PCMTD2

156

Q9NV79
CGLCGDYNGLQSYSE

MUC2

166

Q02817
LGSSEYSKAQCDEYC

LPO

236

P22079
YSKAQCDEYCIQGDN

LPO

241

P22079
NNSYGEKCESCLQGY

MEGF8

2356

Q7Z7M0
SSQGGCLEQDFYYDC

LGR4

831

Q9BXB1
YVACGGLDNICSIYN

GNB4

111

Q9HAV0
ALLQCQGEPECSYAY

GAS1

51

P54826
DSYQDYRNGKCVSCG

LIPH

271

Q8WWY8
NYYLCDGVDDCHDNS

LRP2

1041

P98164
NDCGDYSDERGCLYQ

LRP2

3016

P98164
CEDCGYTGPTQEDLY

OVOL2

216

Q9BRP0
DSCGGLYYHDNNLLS

RASGEF1B

26

Q0VAM2
YYFTLLENCGCADLG

NBAS

1761

A2RRP1
AESNCNYKDGAYENC

MFAP3

346

P55082
YCGRELEQYGQCVAA

CHCHD5

11

Q9BSY4
GLCTNGCKYEDLYSN

CRISP3

201

P54108
YVACGGLDNICSIYN

GNB1

111

P62873
DYGYQCLEGKDCASF

GABRG1

401

Q8N1C3
YKCICNSGYEVDSTG

FBN1

746

P35555
YAANYCDGECSFPLN

BMP6

436

P22004
GKCLNYSLVCDGYDD

CORIN

316

Q9Y5Q5
YSLVCDGYDDCGDLS

CORIN

321

Q9Y5Q5
SYTCLACEEGYRGQS

LTBP2

991

Q14767
LGNLYSEGDCTYLKC

MCCC1

586

Q96RQ3
GGKRCSECQENYYGD

LAMB4

1106

A4D0S4
CQLGSSLYNGCQETY

KRTAP15-1

41

Q3LI76
YRCNCNSGYEPDASG

FBN2

791

P35556
GSFQCECPQGYYLSE

FBN2

1671

P35556
GCSLNCVDDSQDYYV

PSCA

56

O43653
DECENDYYNGGCVHE

SCUBE1

76

Q8IWY4
NQCVSCRAGTYYDGA

SCUBE2

636

Q9NQ36
ISGLQAEDEADYYCC

IGLV2-11

96

P01706
VCSLDCEYYNEGLGE

OTOGL

1201

Q3ZCN5
GFSGNLCQLDIDYCE

JAG1

516

P78504
SGLYYCDICHQDDAS

PLEKHM1

851

Q9Y4G2
LEEYNGERFCYGCQG

GTF2H2C;

336

Q6P1K8
LNTLGSYQCACEPGY

TLL1

591

O43897
CSEGYIQNYRCRGDD

PLPP3

171

O14495
NEPTYCLCNQVSYGE

ING1

351

Q9UK53
CDGCEYLGESYLSNQ

KCP

781

Q6ZWJ8
DCYGNYDNLLSQFGC

PDPK1

371

O15530
VNCNCYSGDDAYATD

TENM2

1526

Q9NT68
ESYTCSCAQGYRLGE

PROZ

146

P22891
CKQGTYSYSGLETCE

SVEP1

1056

Q4LDE5
GSYINSTCGLCGNYN

TECTA

451

O75443
EGGLYYCQARTDASC

TECTA

1086

O75443
CGCDREKQGYYNQAE

WNT7B

131

P56706
ESGDAFDIQRCYCNY

TBXAS1

171

P24557
GCLLYKEGQYEAACS

TTC30B

161

Q8N4P2
YYHQLTEGCGNEACT

UBE3A

36

Q05086
GEGQKECYNLCSQYL

ZNF519

91

Q8TB69
AEFYGATECNCSLGN

SLC27A4

381

Q6P1M0
LEEYNGERFCYGCQG

GTF2H2

336

Q13888
KNDANCDCYQSGDGY

TENM3

1451

Q9P273
GRDCISCKYGQDYST

TNFRSF10B

91

O14763
YYDALCSGEICNTEG

TMOD4

146

Q9NZQ9
LTGDNQYYCENCASL

USP38

731

Q8NB14
GCLLYKEGQYEAACS

TTC30A

161

Q86WT1
GDFGYCDLNYCEEAV

F2

281

P00734
GLNINYNCEICGNYT

SF3A3

401

Q12874
DPYYENCCGGAELSL

SYCN

46

Q0VAF6
TVAQDNCYASYGLCG

GTF3C2

671

Q8WUA4
FADDIGSNNCGYYDL

USP14

406

P54578
EVNSYSCLCAEGYSG

SLIT1

1101

O75093
ALSYSCQCQDGYSGA

SLIT1

1396

O75093
GLGCCYSSEEVNSCY

ZP4

166

Q12836
DCGCTSNGIYYQLGS

ZAN

2651

Q9Y493
NQKGCDGDRLYYDGC

NADSYN1

231

Q6IA69