Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	heme binding	TPO SRC CYP20A1 PTGS2 PXDN SUOX PXDNL NOS3	1.00e-04	154	186	8	GO:0020037
GeneOntologyMolecularFunction	tetrapyrrole binding	TPO SRC CYP20A1 PTGS2 PXDN SUOX PXDNL NOS3	1.55e-04	164	186	8	GO:0046906
GeneOntologyBiologicalProcess	transcription-coupled nucleotide-excision repair	ERCC5 ERCC6 XAB2 USP7	1.23e-06	10	184	4	GO:0006283
GeneOntologyCellularComponent	dendrite	ADCY10 ADCY4 MAOB ITSN1 SRC ZDHHC5 GRIA1 MAGEE1 CHRNA4 ADD1 ZWINT STX4 KCNC4 SACS P2RX2 C4A C4B TANC1 PLEC PCDH8	1.05e-04	858	189	20	GO:0030425
GeneOntologyCellularComponent	dendritic tree	ADCY10 ADCY4 MAOB ITSN1 SRC ZDHHC5 GRIA1 MAGEE1 CHRNA4 ADD1 ZWINT STX4 KCNC4 SACS P2RX2 C4A C4B TANC1 PLEC PCDH8	1.08e-04	860	189	20	GO:0097447
GeneOntologyCellularComponent	basement membrane	COL6A1 COL15A1 COL28A1 LAD1 FREM1 DST PXDN	1.23e-04	122	189	7	GO:0005604
GeneOntologyCellularComponent	perinuclear region of cytoplasm	ADCY10 GAK UACA MEX3D SRC ADGRV1 MAGEE1 CCIN HEPH ADD1 EXOC8 FAT1 VPS52 STX4 DST SYNJ1 CCDC42 TNRC6A PLEC PCSK9	3.20e-04	934	189	20	GO:0048471
Domain	An_peroxidase	TPO PTGS2 PXDN PXDNL	1.91e-06	10	186	4	PF03098
Domain	Haem_peroxidase_animal	TPO PTGS2 PXDN PXDNL	1.91e-06	10	186	4	IPR019791
Domain	Haem_peroxidase	TPO PTGS2 PXDN PXDNL	1.91e-06	10	186	4	IPR010255
Domain	PEROXIDASE_3	TPO PTGS2 PXDN PXDNL	1.91e-06	10	186	4	PS50292
Domain	-	TPO PTGS2 PXDN PXDNL	1.91e-06	10	186	4	1.10.640.10
Domain	-	EVPL DST PLEC	1.90e-05	6	186	3	3.90.1290.10
Domain	PEROXIDASE_1	TPO PXDN PXDNL	1.90e-05	6	186	3	PS00435
Domain	LH2	PKD1L1 PKDREJ LOXHD1 ALOX12	2.61e-05	18	186	4	SM00308
Domain	Plectin	EVPL DST PLEC	3.30e-05	7	186	3	PF00681
Domain	Plectin_repeat	EVPL DST PLEC	3.30e-05	7	186	3	IPR001101
Domain	PLEC	EVPL DST PLEC	3.30e-05	7	186	3	SM00250
Domain	-	PKD1L1 PKDREJ LOXHD1 ALOX12	4.99e-05	21	186	4	2.60.60.20
Domain	PLAT	PKD1L1 PKDREJ LOXHD1 ALOX12	4.99e-05	21	186	4	PF01477
Domain	PLAT/LH2_dom	PKD1L1 PKDREJ LOXHD1 ALOX12	4.99e-05	21	186	4	IPR001024
Domain	PLAT	PKD1L1 PKDREJ LOXHD1 ALOX12	4.99e-05	21	186	4	PS50095
Domain	Spectrin_repeat	EVPL DST PLEC MCF2L	1.86e-04	29	186	4	IPR002017
Domain	SPEC	EVPL DST PLEC MCF2L	2.75e-04	32	186	4	SM00150
Domain	Spectrin/alpha-actinin	EVPL DST PLEC MCF2L	2.75e-04	32	186	4	IPR018159
Domain	VWF_type-D	ZAN VWDE MUC4	4.95e-04	16	186	3	IPR001846
Domain	VWFD	ZAN VWDE MUC4	4.95e-04	16	186	3	PS51233
Domain	VWD	ZAN VWDE MUC4	4.95e-04	16	186	3	SM00216
Domain	VWD	ZAN VWDE MUC4	4.95e-04	16	186	3	PF00094
Domain	REJ	PKD1L1 PKDREJ	5.84e-04	4	186	2	PS51111
Domain	REJ_dom	PKD1L1 PKDREJ	5.84e-04	4	186	2	IPR014010
Domain	C345C	C4A C4B PCOLCE2	5.96e-04	17	186	3	SM00643
Domain	Guanylate_cyc	ADCY10 ADCY4 GUCY1B2	8.37e-04	19	186	3	PF00211
Domain	NTR	C4A C4B PCOLCE2	8.37e-04	19	186	3	PF01759
Domain	GUANYLATE_CYCLASE_2	ADCY10 ADCY4 GUCY1B2	8.37e-04	19	186	3	PS50125
Domain	A/G_cyclase	ADCY10 ADCY4 GUCY1B2	8.37e-04	19	186	3	IPR001054
Domain	Netrin_module_non-TIMP	C4A C4B PCOLCE2	8.37e-04	19	186	3	IPR018933
Domain	GUANYLATE_CYCLASE_1	ADCY10 ADCY4 GUCY1B2	8.37e-04	19	186	3	PS00452
Domain	CYCc	ADCY10 ADCY4 GUCY1B2	8.37e-04	19	186	3	SM00044
Domain	Anaphylatoxin_comp_syst	C4A C4B	9.67e-04	5	186	2	IPR018081
Domain	Anaphylatoxn_comp_syst_dom	C4A C4B	9.67e-04	5	186	2	IPR001840
Pathway	REACTOME_COLLAGEN_FORMATION	COL6A1 COL15A1 COL28A1 DST PXDN PCOLCE2 PLEC	2.81e-05	90	138	7	M631
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	EP400 SEMA7A MRPL55 MEX3D LAD1 ZDHHC5 FRYL LRRK1 PLXND1 LPIN3 HAUS4 FAT1 STX4 DST SYNJ1 HELZ2 USP7 TANC1 WDFY3 PLEC HERC2 MCF2L SPEN	4.10e-08	1105	189	23	35748872
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	GAK EP400 AAMDC ITSN1 TOPBP1 RTN3 ZWINT BLK YEATS2 HAUS4 SYNJ1 TNRC6A USP7 TANC1 SPEN FAM135A	1.63e-07	588	189	16	38580884
Pubmed	LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.	UACA FRYL PHKB PXDN NUP210 CRYBG1 UTP20 PLEC HERC2 TOP2B	1.79e-07	202	189	10	33005030
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	CUL3 CHAF1B EXO5 ERCC5 EP400 UACA ITSN1 ADD1 EFTUD2 YEATS2 ZNF106 HELZ2 USP7 UTP20 PLEC SPEN TOP2B ANKS1A	2.72e-07	774	189	18	15302935
Pubmed	The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.	IARS1 ITSN1 EXOC8 YEATS2 FAT1 MEX3A DST PXDN SACS HELZ2 PLEC SEC14L5	3.16e-07	332	189	12	37433992
Pubmed	Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.	CHAF1B EP400 HELB HAUS4 NUP210 TNRC6A USP7 CRYBG1 BSCL2 SPEN MUC4 HYDIN TOP2B ANKS1A	3.30e-07	469	189	14	27634302
Pubmed	E-cadherin interactome complexity and robustness resolved by quantitative proteomics.	UACA LAD1 SRC ZDHHC5 EVPL ADD1 ARHGDIB STX4 DST SYNJ1 CASKIN2 CRYBG1 TANC1 PLEC MPP7	5.47e-07	565	189	15	25468996
Pubmed	Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.	EP400 UACA TOPBP1 PLXND1 XAB2 MED4 DST AARS2	6.05e-07	130	189	8	12421765
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	CUL3 EP400 TOPBP1 LRRK1 PLXND1 ADGRV1 KBTBD2 HEPH DST CASKIN2 DHCR24 TNRC6A EXOSC7 ANKS1A	1.37e-06	529	189	14	14621295
Pubmed	Genomic analysis of mouse retinal development.	CHAF1B GAK AAMDC SRC ADNP2 HKDC1 FRYL CCNQ XAB2 PTP4A1 LENG8 CSNK1A1L DST CARF UTP20 WDFY3 PLEC MCF2L FAM135A	2.78e-06	1006	189	19	15226823
Pubmed	A human MAP kinase interactome.	CCDC186 ITSN1 SRC ADNP2 EVPL LENG8 RGL1 ZNF106 DST TNRC6A C4A PLEC HERC2	2.94e-06	486	189	13	20936779
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	CUL3 AHCYL1 PGS1 RPS6KA1 XAB2 POLR3A EXOC8 RUSC2 LPIN3 DST CASKIN2 C4A C4B KIF2A TANC1	3.07e-06	650	189	15	38777146
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	CUL3 AHCYL1 RPL31 ADCY4 GAK RPL35A IARS1 ITSN1 RTN3 GRIA1 PTGS2 ADD1 PHKB CSNK1A1L DST SYNJ1 SACS USP7 C4A C4B KIF2A TANC1 PLEC	3.59e-06	1431	189	23	37142655
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	CUL3 RPL31 RPL35A ERCC6 UACA IARS1 LAD1 EVPL XAB2 ADD1 EFTUD2 DST NUP210 HELZ2 USP7 CRYBG1 UTP20 KIF2A PLEC SPEN EXOSC7	5.46e-06	1257	189	21	36526897
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	RPL31 EP400 CCDC186 SRC ZDHHC5 PLXND1 KBTBD2 TRIM23 ADD1 EFTUD2 FAT1 VPS52 DST TNRC6A SPEN FAM135A	6.06e-06	777	189	16	35844135
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	CUL3 ITSN1 PKD1L1 KBTBD2 LENG8 PHKB HAUS4 VPS52 MED4 SYNJ1 TNRC6A TANC1 PLEC HERC2 EXOSC7 ANKS1A	1.91e-05	853	189	16	28718761
Pubmed	Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.	ITSN1 SRC ZDHHC5 RTN3 ADD1 RUSC2 DST SYNJ1 SACS PLEC	2.23e-05	347	189	10	17114649
Pubmed	Defining the membrane proteome of NK cells.	CUL3 RPL31 GAK RPL35A PDGFRB IARS1 MFSD6 CYP20A1 ZDHHC5 XAB2 POLR3A EXOC8 EFTUD2 MED4 DHCR24 NUP210 HELZ2 KIF2A HERC2	2.26e-05	1168	189	19	19946888
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	RPL35A ERCC6 EP400 UACA TOPBP1 XAB2 LENG8 MED4 DST PXDN DHCR24 TNRC6A HELZ2 USP7 CRYBG1 UTP20 KIF2A TANC1 HERC2 SPEN EXOSC7 MPP7	2.36e-05	1497	189	22	31527615
Pubmed	Copy number analysis of complement C4A, C4B and C4A silencing mutation by real-time quantitative polymerase chain reaction.	C4A C4B	2.94e-05	2	189	2	22737222
Pubmed	Deficiency of C4 from donor or recipient mouse fails to prevent renal allograft rejection.	C4A C4B	2.94e-05	2	189	2	16565498
Pubmed	Complete deficiencies of complement C4A and C4B including 2-bp insertion in codon 1213 are genetic risk factors of systemic lupus erythematosus in Thai populations.	C4A C4B	2.94e-05	2	189	2	15998580
Pubmed	Phosducin influences sympathetic activity and prevents stress-induced hypertension in humans and mice.	PDC PTGS2	2.94e-05	2	189	2	19959875
Pubmed	Stimulatory roles of nitric-oxide synthase 3 and guanylyl cyclase in platelet activation.	ADCY10 NOS3	2.94e-05	2	189	2	16144836
Pubmed	High-throughput analysis of the C4 polymorphism by a combination of MLPA and isotype-specific ELISA's.	C4A C4B	2.94e-05	2	189	2	19062096
Pubmed	Validation of PDGFRbeta and c-Src tyrosine kinases as tumor/vessel targets in patients with multiple myeloma: preclinical efficacy of the novel, orally available inhibitor dasatinib.	PDGFRB SRC	2.94e-05	2	189	2	18524994
Pubmed	Activation of innate and humoral immunity in the peripheral nervous system of ALS transgenic mice.	C4A C4B	2.94e-05	2	189	2	19933335
Pubmed	Structural basis for the C4d.1/C4d.2 serologic allotypes of murine complement component C4.	C4A C4B	2.94e-05	2	189	2	2459207
Pubmed	Genome Maintenance by DNA Helicase B.	TOPBP1 HELB	2.94e-05	2	189	2	32455610
Pubmed	Antigen-induced B cell apoptosis is independent of complement C4.	C4A C4B	2.94e-05	2	189	2	17645767
Pubmed	Anti-DNA autoreactivity in C4-deficient mice.	C4A C4B	2.94e-05	2	189	2	12207352
Pubmed	Cooperative enzymatic control of N-acyl amino acids by PM20D1 and FAAH.	PM20D1 FAAH	2.94e-05	2	189	2	32271712
Pubmed	Complement C4A and C4B Gene Copy Number Study in Alzheimer's Disease Patients.	C4A C4B	2.94e-05	2	189	2	27758680
Pubmed	Genetically determined partial complement C4 deficiency states are not independent risk factors for SLE in UK and Spanish populations.	C4A C4B	2.94e-05	2	189	2	22387014
Pubmed	Complement C4 maintains peripheral B-cell tolerance in a myeloid cell dependent manner.	C4A C4B	2.94e-05	2	189	2	23749435
Pubmed	Copy number variations of complement component C4 are associated with Behçet's disease but not with ankylosing spondylitis associated with acute anterior uveitis.	C4A C4B	2.94e-05	2	189	2	23918728
Pubmed	Src phosphorylation of RhoGDI2 regulates its metastasis suppressor function.	SRC ARHGDIB	2.94e-05	2	189	2	19321744
Pubmed	Cyclooxygenase-2 is a target gene of rho GDP dissociation inhibitor beta in breast cancer cells.	PTGS2 ARHGDIB	2.94e-05	2	189	2	18006811
Pubmed	Molecular genetics of androgen-dependent and -independent expression of mouse sex-limited protein.	C4A C4B	2.94e-05	2	189	2	3037333
Pubmed	Evidence of a role for C4 in modulating interstitial inflammation in experimental glomerulonephritis.	C4A C4B	2.94e-05	2	189	2	11726230
Pubmed	Quantitative variations in the expression of the mouse serum antigen Ss and its sex-limited allotype Slp.	C4A C4B	2.94e-05	2	189	2	4216347
Pubmed	Sequence determination of the thiolester site of the fourth component of human complement.	C4A C4B	2.94e-05	2	189	2	6950384
Pubmed	Visual demonstration of the organization of the human complement C4 and 21-hydroxylase genes by high-resolution fluorescence in situ hybridization.	C4A C4B	2.94e-05	2	189	2	8660986
Pubmed	Tissue-specific RNA processing for the complement C4 gene transcript in the H-2k mouse strain.	C4A C4B	2.94e-05	2	189	2	8428773
Pubmed	Complement C4 deficiency--a plausible risk factor for non-tuberculous mycobacteria (NTM) infection in apparently immunocompetent patients.	C4A C4B	2.94e-05	2	189	2	24638111
Pubmed	Transcriptional repression of C4 complement by hepatitis C virus proteins.	C4A C4B	2.94e-05	2	189	2	21345967
Pubmed	Polymorphisms of DNA repair-related genes with susceptibility and prognosis of prostate cancer.	ERCC5 ERCC6	2.94e-05	2	189	2	24615090
Pubmed	Microexon-based regulation of ITSN1 and Src SH3 domains specificity relies on introduction of charged amino acids into the interaction interface.	ITSN1 SRC	2.94e-05	2	189	2	20659428
Pubmed	Restriction fragment analysis of H-2 recombinant mouse strains with crossovers between E alpha and C4 genes.	C4A C4B	2.94e-05	2	189	2	2572548
Pubmed	The complement component C4 of mammals.	C4A C4B	2.94e-05	2	189	2	2302180
Pubmed	COX-2, TFF1, and Src define better prognosis in young patients with gastric cancer.	SRC PTGS2	2.94e-05	2	189	2	24037722
Pubmed	Gene CNVs and protein levels of complement C4A and C4B as novel biomarkers for partial disease remissions in new-onset type 1 diabetes patients.	C4A C4B	2.94e-05	2	189	2	22151770
Pubmed	C4d-positive chronic rejection: a frequent entity with a poor outcome.	C4A C4B	2.94e-05	2	189	2	18091514
Pubmed	Comprehensive approach to study complement C4 in systemic lupus erythematosus: Gene polymorphisms, protein levels and functional activity.	C4A C4B	2.94e-05	2	189	2	29080553
Pubmed	Associations of functional polymorphisms in cyclooxygenase-2 and platelet 12-lipoxygenase with risk of occurrence and advanced disease status of colorectal cancer.	PTGS2 ALOX12	2.94e-05	2	189	2	17151091
Pubmed	Genes for murine fourth complement component (C4) and sex-limited protein (Slp) identified by hybridization to C4- and Slp-specific cDNA.	C4A C4B	2.94e-05	2	189	2	6589636
Pubmed	C4 Deficiency is a predisposing factor for Streptococcus pneumoniae-induced autoantibody production.	C4A C4B	2.94e-05	2	189	2	25339671
Pubmed	A study of association of the complement C4 mutations with systemic lupus erythematosus in the Malaysian population.	C4A C4B	2.94e-05	2	189	2	17728371
Pubmed	Role of c-Src in regulation of endothelial nitric oxide synthase expression during exercise training.	SRC NOS3	2.94e-05	2	189	2	12595302
Pubmed	Structure and organization of the C4 genes.	C4A C4B	2.94e-05	2	189	2	6149580
Pubmed	Sequence heterogeneity of murine complementary DNA clones related to the C4 and C4-Slp isoforms of the fourth complement component.	C4A C4B	2.94e-05	2	189	2	6149581
Pubmed	The follicular dendritic cell restricted epitope, FDC-M2, is complement C4; localization of immune complexes in mouse tissues.	C4A C4B	2.94e-05	2	189	2	12115608
Pubmed	Biochemistry and biology of anaphylatoxins.	C4A C4B	2.94e-05	2	189	2	3542363
Pubmed	C4 from C4-high and C4-low mouse strains have identical sequences in the region corresponding to the isotype-specific segment of human C4.	C4A C4B	2.94e-05	2	189	2	2387317
Pubmed	Expression of cyclooxygenase-2 and 12-lipoxygenase in human breast cancer and their relationship with HER-2/neu and hormonal receptors: impact on prognosis and therapy.	PTGS2 ALOX12	2.94e-05	2	189	2	17192687
Pubmed	Identification of the size and antigenic determinants of the human C4 gene by a polymerase chain-reaction-based amplification method.	C4A C4B	2.94e-05	2	189	2	16908004
Pubmed	Structural studies on the murine fourth component of complement (C4). IV. Demonstration that C4 and Slp are encoded by separate loci.	C4A C4B	2.94e-05	2	189	2	7365238
Pubmed	Interaction between the labile binding sites of the fourth (C4) and fifth (C5) human complement proteins and erythrocyte cell membranes.	C4A C4B	2.94e-05	2	189	2	7391573
Pubmed	Peritubular capillary C4d deposition in lupus nephritis different from antibody-mediated renal rejection.	C4A C4B	2.94e-05	2	189	2	17971360
Pubmed	Clinical features of patients with homozygous complement C4A or C4B deficiency.	C4A C4B	2.94e-05	2	189	2	29928053
Pubmed	Analysis of C4 and the C4 binding protein in the MRL/lpr mouse.	C4A C4B	2.94e-05	2	189	2	17971229
Pubmed	Genetic deficiency of C4 presenting with recurrent infections and a SLE-like disease. Genetic and immunologic studies.	C4A C4B	2.94e-05	2	189	2	6881182
Pubmed	Syntaxin-4 defines a domain for activity-dependent exocytosis in dendritic spines.	GRIA1 STX4	2.94e-05	2	189	2	20434989
Pubmed	Induction of cyclooxygenase-2 gene in pancreatic beta-cells by 12-lipoxygenase pathway product 12-hydroxyeicosatetraenoic acid.	PTGS2 ALOX12	2.94e-05	2	189	2	12198250
Pubmed	Partial C4 deficiency in juvenile idiopathic arthritis patients.	C4A C4B	2.94e-05	2	189	2	17921792
Pubmed	Complement activation and complement receptors on follicular dendritic cells are critical for the function of a targeted adjuvant.	C4A C4B	2.94e-05	2	189	2	21880985
Pubmed	Amino acid sequence around the thiol and reactive acyl groups of human complement component C4.	C4A C4B	2.94e-05	2	189	2	6978711
Pubmed	Plasma Complement 3 and Complement 4 Are Promising Biomarkers for Distinguishing NMOSD From MOGAD and Are Associated With the Blood-Brain-Barrier Disruption in NMOSD.	C4A C4B	2.94e-05	2	189	2	35898513
Pubmed	Borrelia burgdorferi outer surface protein C (OspC) binds complement component C4b and confers bloodstream survival.	C4A C4B	2.94e-05	2	189	2	28873507
Pubmed	Studies on the murine Ss protein: demonstration that the Ss protein is functionally the fourth component of complement.	C4A C4B	2.94e-05	2	189	2	276882
Pubmed	Amino acid sequence of a polymorphic segment from fragment C4d of human complement component C4.	C4A C4B	2.94e-05	2	189	2	6832377
Pubmed	Recombination of two homologous MHC class III genes of the mouse (C4 and Slp) that accounts for the loss of testosterone dependence of sex-limited protein expression.	C4A C4B	2.94e-05	2	189	2	3794341
Pubmed	COX-2 contributes to the maintenance of flow-induced dilation in arterioles of eNOS-knockout mice.	PTGS2 NOS3	2.94e-05	2	189	2	16632543
Pubmed	Fine-tuned characterization of RCCX copy number variants and their relationship with extended MHC haplotypes.	C4A C4B	2.94e-05	2	189	2	22785613
Pubmed	Association between complement 4 copy number variation and systemic lupus erythematosus: a meta-analysis.	C4A C4B	2.94e-05	2	189	2	32691186
Pubmed	Semaphorin 7a exerts pleiotropic effects to promote breast tumor progression.	SEMA7A PTGS2	2.94e-05	2	189	2	27065336
Pubmed	A DNA-topoisomerase-II-binding protein with eight repeating regions similar to DNA-repair enzymes and to a cell-cycle regulator.	TOPBP1 TOP2B	2.94e-05	2	189	2	9461304
Pubmed	The androgen-dependent C4-Slp gene is driven by a constitutively competent promoter.	C4A C4B	2.94e-05	2	189	2	8390682
Pubmed	Structure and expression of murine fourth complement component (C4) and sex-limited protein (Slp).	C4A C4B	2.94e-05	2	189	2	3902619
Pubmed	Pathways of metastasis suppression in bladder cancer.	SRC ARHGDIB	2.94e-05	2	189	2	20013033
Pubmed	Structural polymorphism of murine C4 and its linkage to H-2.	C4A C4B	2.94e-05	2	189	2	7373044
Pubmed	The chemical structure of the C4d fragment of the human complement component C4.	C4A C4B	2.94e-05	2	189	2	3696167
Pubmed	Restriction fragment length polymorphism of the murine C4 and Slp genes: two C4 groups.	C4A C4B	2.94e-05	2	189	2	1357031
Pubmed	Structural comparison of human C4A3 and C4B1 after proteolytic activation by C1s.	C4A C4B	2.94e-05	2	189	2	16098595
Pubmed	Increased frequency of C4B*Q0 alleles in patients with Henoch-Schönlein purpura.	C4A C4B	2.94e-05	2	189	2	15787745
Pubmed	Neuropil contraction in relation to Complement C4 gene copy numbers in independent cohorts of adolescent-onset and young adult-onset schizophrenia patients-a pilot study.	C4A C4B	2.94e-05	2	189	2	30026462
Pubmed	A molecular map of the human major histocompatibility complex class III region linking complement genes C4, C2 and factor B.	C4A C4B	2.94e-05	2	189	2	6559257
Pubmed	Histamine-dependent prolongation by aldosterone of vasoconstriction in isolated small mesenteric arteries of the mouse.	PTGS2 NOS3	2.94e-05	2	189	2	23396453
Pubmed	Complement C4 Is Reduced in iPSC-Derived Astrocytes of Autism Spectrum Disorder Subjects.	C4A C4B	2.94e-05	2	189	2	34299197
Pubmed	Assessment of complement C4 gene copy number using the paralog ratio test.	C4A C4B	2.94e-05	2	189	2	20506482
Interaction	SPTAN1 interactions	CUL3 GAK ITSN1 SRC EPB41L4A ADD1 EFTUD2 MED4 MEX3A STX4 DST PXDN PXDNL ZNF197 TBCK USP7 KIF2A TANC1 PLEC	1.81e-07	496	186	19	int:SPTAN1
Interaction	PROK2 interactions	ADGRV1 VWDE TMBIM1 LENG8	6.54e-06	14	186	4	int:PROK2
GeneFamily	EF-hand domain containing\|Plakins	EVPL DST PLEC	1.68e-05	8	123	3	939
GeneFamily	WD repeat domain containing\|ERCC excision repair associated	ERCC5 ERCC6	9.43e-04	7	123	2	1268
GeneFamily	C3 and PZP like, alpha-2-macroglobulin domain containing	C4A C4B	1.60e-03	9	123	2	1234
GeneFamily	WD repeat domain containing\|BEACH domain containing	WDFY3 NSMAF	1.60e-03	9	123	2	1230
GeneFamily	Adenylate cyclases\|Deafness associated genes	ADCY10 ADCY4	1.99e-03	10	123	2	53
GeneFamily	Glycosyltransferase family 6\|Blood group antigens	SEMA7A C4A C4B	2.02e-03	37	123	3	454
Coexpression	ACEVEDO_METHYLATED_IN_LIVER_CANCER_DN	TPO ADAD1 CCDC186 ITSN1 HKDC1 NHLRC3 LRRK1 ADGRV1 ADD1 POLR3A CCDC7 CCDC196 MSRA CSNK1A1L PXDN PXDNL OTOP1 TDRD6 MUC4 TREML2 PUS7L	1.49e-06	873	189	21	M16009
Coexpression	GAL_LEUKEMIC_STEM_CELL_UP	COL6A1 EXO5 MFSD6 EVPL TRIM23 DST KBTBD4 WDFY3	4.83e-06	130	189	8	M17428
Coexpression	GSE14908_RESTING_VS_HDM_STIM_CD4_TCELL_NONATOPIC_PATIENT_DN	VPS11 NT5C3A IER5 XAB2 PHKB ARHGDIB SUOX TNRC6A BSCL2	1.57e-05	200	189	9	M7080
Coexpression	GSE17721_POLYIC_VS_CPG_2H_BMDC_DN	COL6A1 PGS1 COL15A1 LAD1 IER5 CRY1 RGL1 ABCB8 C4B	1.57e-05	200	189	9	M3939
ToppCell	facs-Marrow-T-cells-3m-Hematologic-MPP_Fraction_B_+_C\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ERCC6 EVPL MAGEE1 EPB41L4A MEX3A AARS2 MYO3B PUS7L	7.13e-07	170	190	8	d70aaa0f4e5034bb9f61b832b5f9123870936d3c
ToppCell	5'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-venous_capillary\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ADCY4 COL15A1 UACA PLXND1 KCNC4 CASKIN2 MCF2L NOS3	1.52e-06	188	190	8	0026c9479b30fb39daa91cfa220a88f9c9e65fe7
ToppCell	Adult-Mesenchymal-matrix_fibroblast_1_cell-D231\|Adult / Lineage, Cell type, age group and donor	COL6A1 COL15A1 MAOB UACA PDGFRB GRIA1 FREM1 GFPT2	1.85e-06	193	190	8	ef2f456c094e6e3c6ee81e0668c953cb8d0e1c0a
ToppCell	10x3'2.3-week_14-16-Mesenchymal_osteo-stroma-osteochondral_precursor\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	COL6A1 RGMB COL15A1 UACA PDGFRB HEPH FAT1 TANC1	2.15e-06	197	190	8	c165c6fd12dc649b39e920d8528e2eb65c61956b
ToppCell	LPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	COL6A1 MAOB PDGFRB ITSN1 FREM1 DST PXDNL GFPT2	2.32e-06	199	190	8	e1849505b92820a219c5a2c35492bdd55579fb48
ToppCell	Parenchymal-NucSeq-Stromal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL6A1 MAOB UACA PDGFRB GRIA1 FREM1 DST GFPT2	2.41e-06	200	190	8	cf433f9b43d7db07acaf70e060f8f77c974e72f3
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL6A1 MAOB UACA PDGFRB GRIA1 FREM1 DST GFPT2	2.41e-06	200	190	8	311fab076f2ceb258e3970eb21e39344b894042a
ToppCell	367C-Lymphocytic-NK_cells-NK_cell_E\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	ITSN1 RUSC2 LPIN3 HAUS4 SUOX ZNF761 THNSL2	7.68e-06	167	190	7	b5d15773be32cd277125fd3b4056a8fefaefa5ec
ToppCell	E16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ADCY4 SEMA7A UACA PLXND1 PLEC NOS3 ALOX12	1.08e-05	176	190	7	77516048aefbe1f48e825052756df0c310c1c486
ToppCell	E16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ADCY4 SEMA7A UACA PLXND1 PLEC NOS3 ALOX12	1.08e-05	176	190	7	96779273b94345250cf53ba671203345b43d9e00
ToppCell	droplet-Liver-LIVER_HEP-30m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP20A1 ADNP2 PLXND1 GABPB2 TANC1 ALOX12 PUS7L	1.49e-05	185	190	7	bdd2e6cb20294b39a9d856004bf57ba69cf877e2
ToppCell	10x3'2.3-week_17-19-Endothelial-stroma-proliferating_EC\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	TPO COL15A1 PLXND1 BFSP1 CASKIN2 TANC1 TDRD6	1.55e-05	186	190	7	a844d4f79e0ad5d6c60a4488ffd8f4f21b7eed04
ToppCell	Adult-Endothelial-capillary_endothelial_cell_(Cap1)-D175\|Adult / Lineage, Cell type, age group and donor	ADCY4 UACA EPB41L4A FAT1 PXDN MCF2L NOS3	1.60e-05	187	190	7	f3548817f2fded5978137bb252cb628ac199e4f6
ToppCell	3'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-cycling_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ADCY4 COL15A1 PLXND1 ZWINT CASKIN2 MCF2L NOS3	1.66e-05	188	190	7	5d166d9e71632edd059ff0a9f66f8763f259d40a
ToppCell	facs-Heart-LV-18m-Endothelial-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADCY4 SEMA7A UACA PLXND1 CASKIN2 MCF2L NOS3	1.66e-05	188	190	7	e5a8ca4613ab0bf1584b9e78959adf41d0bf379f
ToppCell	facs-Heart-LV-18m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADCY4 SEMA7A UACA PLXND1 CASKIN2 MCF2L NOS3	1.66e-05	188	190	7	0fc3a6562e6895f6fe7a93397eae842a75c60c93
ToppCell	facs-Heart-LV-18m-Endothelial-endothelial_cell_of_coronary_artery\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADCY4 SEMA7A UACA PLXND1 CASKIN2 MCF2L NOS3	1.66e-05	188	190	7	ed11e26ff4ef3d6314b5f5734062519b9aa285c1
ToppCell	IPF-Epithelial-Aberrant_Basaloid\|Epithelial / Disease state, Lineage and Cell class	COL6A1 SEMA7A PTGS2 MEX3A DST PXDN MYO3B	1.71e-05	189	190	7	4178be3292ff4a8a1d8098f638d4b8d15164d2c6
ToppCell	E16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ADCY4 SEMA7A UACA PLXND1 PLEC NOS3 ALOX12	1.71e-05	189	190	7	feedac2751ed770f80bc56fec31662b5b3826f58
ToppCell	Control-Fibroblasts\|Control / group, cell type (main and fine annotations)	COL6A1 MAOB UACA GRIA1 FREM1 DST GFPT2	1.77e-05	190	190	7	3a42a9b98d954685d38a741f44545898d0e3e9ce
ToppCell	droplet-Kidney-nan-18m-Endothelial-Pecam____Kidney_cortex_artery_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADCY10 ADCY4 SEMA7A UACA PCOLCE2 NOS3 ALOX12	1.90e-05	192	190	7	c96736bb3a6bb052678b1b078f7823063ca69e6d
ToppCell	droplet-Kidney-nan-18m-Endothelial-kidney_cortex_artery_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADCY10 ADCY4 SEMA7A UACA PCOLCE2 NOS3 ALOX12	1.90e-05	192	190	7	144503af50274eaed5cf6effa892c640eab28663
ToppCell	facs-BAT-Fat-3m-Endothelial-nan\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADCY4 SEMA7A DST CASKIN2 TANC1 MCF2L NOS3	1.96e-05	193	190	7	e340064cd146deac03f2d0fd43e2e218bb6057c9
ToppCell	5'-Adult-Appendix-Endothelial-blood_vessel_EC-Mature_venous_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TPO ADCY4 PLXND1 EPB41L4A PTGS2 MCF2L NOS3	1.96e-05	193	190	7	c0973a2c97deb7176c2f617c8760a55f7edc9839
ToppCell	facs-BAT-Fat-3m-Endothelial-endothelial_cell\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADCY4 SEMA7A DST CASKIN2 TANC1 MCF2L NOS3	1.96e-05	193	190	7	a211b386fd0fb9da9937361d29d90925a72c9715
ToppCell	facs-BAT-Fat-3m-Endothelial\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADCY4 SEMA7A DST CASKIN2 TANC1 MCF2L NOS3	1.96e-05	193	190	7	3086c33f4d6fab66966818737f95ae4d6b2615b0
ToppCell	Adult-Mesenchymal-matrix_fibroblast_1_cell\|Adult / Lineage, Cell type, age group and donor	COL6A1 MAOB UACA PDGFRB GRIA1 FREM1 DST	2.10e-05	195	190	7	61c9e09fc84d1012e472185d70ad0a06cee30d6e
ToppCell	Children_(3_yrs)-Mesenchymal\|Children_(3_yrs) / Lineage, Cell type, age group and donor	COL6A1 UACA PDGFRB GRIA1 FREM1 DST GFPT2	2.17e-05	196	190	7	bc94909f9b2dc08a59eef1914148b69720569c8f
ToppCell	5'-Adult-SmallIntestine-Endothelial-blood_vessel_EC-arterial_capillary\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TPO ADCY4 COL15A1 PLXND1 CASKIN2 MCF2L NOS3	2.17e-05	196	190	7	c5fe470f11ee4962bcfb30cddfd8c078af5b1222
ToppCell	10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-Pericyte-G\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	COL6A1 ADCY4 UACA PDGFRB OR51E1 PXDN PXDNL	2.17e-05	196	190	7	73f029d2b276776d6c24356b14c6592c9cb74bd5
ToppCell	Adult-Mesenchymal\|Adult / Lineage, Cell type, age group and donor	COL6A1 MAOB UACA PDGFRB GRIA1 FREM1 GFPT2	2.31e-05	198	190	7	26e55b409db2a1637c95fae7c54b0abea1ef550c
ToppCell	nucseq-Mesenchymal\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	COL6A1 MAOB UACA PDGFRB GRIA1 DST GFPT2	2.31e-05	198	190	7	8f52243ca8b9ba68a75ae411506a3a6de258eb97
ToppCell	Bronchial-10x5prime-Stromal-Peri/Epineurial_\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	COL6A1 RGMB PDGFRB COL28A1 FREM1 C4A PCDH8	2.39e-05	199	190	7	45c3b853900d8c3d5965117d904e3714100138bc
ToppCell	Sepsis-URO\|Sepsis / Disease, condition lineage and cell class	PLXND1 LENG8 RGL1 DHCR24 PCOLCE2 WDFY3 PLEC	2.39e-05	199	190	7	8e6dac82d1d0e759cd567f9c95b70cb4801d7caf
ToppCell	5'-GW_trimst-2-LargeIntestine-Endothelial\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ADCY4 COL15A1 UACA PLXND1 CASKIN2 MCF2L NOS3	2.39e-05	199	190	7	f0bf75bfae7b288ecb6801be458b03ebd0108ea7
ToppCell	Bronchial-NucSeq-Stromal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL6A1 UACA PDGFRB GRIA1 FREM1 DST GFPT2	2.47e-05	200	190	7	389cc775c8419d90fb77cd794376d2160a7bf44e
ToppCell	LPS_only-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_only / Treatment groups by lineage, cell group, cell type	COL6A1 MAOB PDGFRB ITSN1 FREM1 DST PXDNL	2.47e-05	200	190	7	a7ef7022b8efcaedb7319b0b43d8c4e99d788fe2
ToppCell	Bronchial-NucSeq-Stromal-Fibroblastic-Fibro_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL6A1 MAOB UACA PDGFRB GRIA1 FREM1 DST	2.47e-05	200	190	7	e8462395fee0a532d1e7ec7f1795f28c42af6541
ToppCell	Bronchial-NucSeq-Stromal-Fibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL6A1 UACA PDGFRB GRIA1 FREM1 DST GFPT2	2.47e-05	200	190	7	cae972324d1dfea6efeaf6013f265c7c6bb48db4
ToppCell	5'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ADCY4 COL15A1 UACA PLXND1 CASKIN2 MCF2L NOS3	2.47e-05	200	190	7	90061284a80d29a4ca6078f578e13d32b8cc80e1
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_bronchial_vessel-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	COL15A1 UACA NKIRAS1 PXDN KCNC4 MCF2L	5.63e-05	156	190	6	ff39712c7a2dc1b85c598d5105789aa291dea726
ToppCell	367C-Lymphocytic-NK_cells-NK_cell_E\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	ITSN1 RUSC2 LPIN3 SUOX ZNF761 THNSL2	5.83e-05	157	190	6	432b8719a8afd289cf48068e12c26a349d753fcc
ToppCell	AT1-AT2_cells-Myositis-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	MEX3D PTGS2 FAT1 MYO3B MCF2L MUC4	6.04e-05	158	190	6	3bc51cfd37b289cc3e866b54ce55a298e5eff690
ToppCell	Transplant_Alveoli_and_parenchyma-Epithelial-Type_1_alveolar\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	PDC RIMKLA DST PXDN PLEC ANKS1A	6.48e-05	160	190	6	58ed3a074932ccc951e07868dfdc61b99ae1cc2b
ToppCell	Endothelial-endothelial_cell_of_bronchial_vessel\|World / Lineage, Cell type, age group and donor	ADCY4 COL15A1 UACA KCNC4 TANC1 MCF2L	7.68e-05	165	190	6	84e553d699ac56df89a77248f7308b9133e1b683
ToppCell	TCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Squamous_Cell_Carcinoma-4\|TCGA-Lung / Sample_Type by Project: Shred V9	COL6A1 COL15A1 PDGFRB HEPH PXDN GFPT2	8.48e-05	168	190	6	aefea14b8b1c1b6a05f827effd22ba15274fddc9
ToppCell	10x_3'_v2v3-Neoplastic-Stem-like-OPC-like-OPC-like_Prolif-E\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	UACA FRYL FAT1 MEX3A PXDN ABCD2	8.77e-05	169	190	6	2833a8a7094e4d407eb923f2bc59b9b112c6bae4
ToppCell	facs-Diaphragm-Limb_Muscle-24m\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TPO ZAN ADGRV1 MYO3B C4B HYDIN	8.77e-05	169	190	6	12bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCell	367C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)\|367C / Donor, Lineage, Cell class and subclass (all cells)	MEX3D LAD1 EVPL ADGRV1 DHCR24 PCSK9	9.66e-05	172	190	6	26006967d0c82f7bd9b36a18e97a1b93e856aa67
ToppCell	Control-Endothelial_cells-Systemic_venous_endothelial_cells\|Control / group, cell type (main and fine annotations)	ADCY4 COL15A1 PKD1L1 EPB41L4A MCF2L NOS3	9.66e-05	172	190	6	c55dce1ed3ed7312394b4e050e1de852a994e130
ToppCell	367C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-\|367C / Donor, Lineage, Cell class and subclass (all cells)	MEX3D LAD1 EVPL ADGRV1 DHCR24 PCSK9	9.66e-05	172	190	6	a9e65201ad9ab4f64251aba2c0bb3d8f9e0193b6
ToppCell	tumor_Lymph_Node_/_Brain-T/NK_cells-CD8+/CD4+_Mixed_Th\|T/NK_cells / Location, Cell class and cell subclass	CMBL EXO5 ADGRV1 NKIRAS1 WDFY3 NOS3	9.97e-05	173	190	6	42c911ed16fabdabef063830e8407192d8bde950
ToppCell	facs-Liver-Liver_non-hepato/SCs_st-18m-Lymphocytic-B_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPL31 IER5 BLK ARHGDIB SLC4A11 TREML2	1.10e-04	176	190	6	0f056597bc9e53176ce8670924ac925c801964b5
ToppCell	facs-Liver-Liver_non-hepato/SCs_st-18m-Lymphocytic-B_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPL31 IER5 BLK ARHGDIB SLC4A11 TREML2	1.10e-04	176	190	6	d04be5acf0be46adc3d2055f6f21358c02792817
ToppCell	Thalamus-Macroglia-OLIGODENDROCYTE-O1-Trf\|Thalamus / BrainAtlas - Mouse McCarroll V32	PKD1L1 ADGRV1 PCOLCE2 MUC4 SEC14L5	1.19e-04	112	190	5	cb351e57c99aaaf9ae6c7ff7e8ce5375552b1639
ToppCell	Thalamus-Macroglia-OLIGODENDROCYTE-O1-Trf-Oligodendrocyte.Trf.Il33_(Il33)\|Thalamus / BrainAtlas - Mouse McCarroll V32	PKD1L1 ADGRV1 PCOLCE2 MUC4 SEC14L5	1.19e-04	112	190	5	999b5eeed4305e1a1385aadbaf017b64f21c1ee0
ToppCell	Thalamus-Macroglia-OLIGODENDROCYTE-O1-Trf-Oligodendrocyte.Trf.Il33_(Il33)-\|Thalamus / BrainAtlas - Mouse McCarroll V32	PKD1L1 ADGRV1 PCOLCE2 MUC4 SEC14L5	1.19e-04	112	190	5	004cd69b66c3b26b9a61f03279b48230da351574
ToppCell	Thalamus-Macroglia-OLIGODENDROCYTE-O1\|Thalamus / BrainAtlas - Mouse McCarroll V32	PKD1L1 ADGRV1 PCOLCE2 MUC4 SEC14L5	1.19e-04	112	190	5	502e3f356f6e1c959bff0a39c98f33f863ce8265
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ADGRV1 LENG8 TANC1 MCF2L MUC4 SLC4A11	1.20e-04	179	190	6	6e965e424eebef50f0202cff75f458be395cfca1
ToppCell	droplet-Limb_Muscle-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPL31 RPL35A PTGS2 C4B PCOLCE2 GFPT2	1.20e-04	179	190	6	013818e173101efca7625ccd4258e60655815d73
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-venous_capillary\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ADCY4 COL15A1 UACA PLXND1 ARHGDIB MCF2L	1.24e-04	180	190	6	97e0dcb7cfbba60a782824c5e23995058609fcd4
ToppCell	Fetal_29-31_weeks-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	TPO PLXND1 EPB41L4A PXDN CASKIN2 HELZ2	1.24e-04	180	190	6	d8ef44710a77ad0fc03243428e5e1dc4d41200cb
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-Pecam____fenestrated_capillary_endothelial\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL15A1 PDGFRB PXDN SACS TDP1 ABCD2	1.24e-04	180	190	6	79c5725f02e038d0187f4a1e1591f2492538aa57
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-DN4_thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RIMKLA MFSD6 SRC DNAJC27 LRRK1 POLR3A	1.24e-04	180	190	6	be10fe5bf7c3a671c42704ce7dd8226ab6896794
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-DN4_thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RIMKLA MFSD6 SRC DNAJC27 LRRK1 POLR3A	1.24e-04	180	190	6	3b747a517ce75ef2ff09011c037dad7b01ed3e03
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Epithelial-neuroepithelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADCY10 COL6A1 IER5 C4B GFPT2 MPP7	1.28e-04	181	190	6	c26d3cbbc592299786d79d1b15fc6bead2aafb9a
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Endothelial-blood_vessel_EC-cycling_EC\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL15A1 PLXND1 ZWINT ARHGDIB LOXHD1 SLC4A11	1.28e-04	181	190	6	4a225d9a6d113396c6b1d0a839bb4ca9c339a260
ToppCell	5'-Airway_Nasal-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells-\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MAOB SEMA7A PM20D1 VWDE KCNC4 ABCB8	1.32e-04	182	190	6	4cd5eb13f78f4f377932c50ac2acb4ac0cd14c12
ToppCell	droplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l19\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ADCY4 SEMA7A UACA FRYL PLXND1 NOS3	1.32e-04	182	190	6	840427d1c23d60482c943ff006b14007ed44d247
ToppCell	COVID-19-Heart-Fib_+_EC_+_Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	TPO COL6A1 COL15A1 PDGFRB PXDN GFPT2	1.32e-04	182	190	6	fbd5e332df73bf7141c822fa67b76367dc962017
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.1.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ZDHHC5 CASKIN2 DHCR24 WDFY3 PLK4 PCSK9	1.36e-04	183	190	6	91079a11685dd466bd27a0cf5afbf3734c08a05e
ToppCell	COVID-19-Heart-EC_3\|COVID-19 / Disease (COVID-19 only), tissue and cell type	TPO ADCY4 COL15A1 EPB41L4A MCF2L NOS3	1.36e-04	183	190	6	ff95382cfed592190d0636d2b750328471f82e0d
ToppCell	3'-GW_trimst-2-SmallIntestine-Endothelial-blood_vessel_EC-cycling_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL15A1 PLXND1 ZWINT CASKIN2 NOS3 SLC4A11	1.40e-04	184	190	6	fa38d6a8709f520a027ad7e3ff783c84187ec467
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZAN ADGRV1 FREM1 FAT1 LOXHD1 HYDIN	1.40e-04	184	190	6	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Skin-Skin_Anagen-18m-Mesenchymal-fibroblast\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDGFRB RIMKLA PLXND1 RUSC2 PCOLCE2 GFPT2	1.40e-04	184	190	6	fea4fe648e9749177d0783443dc26a7df5807883
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZAN ADGRV1 FREM1 FAT1 LOXHD1 HYDIN	1.40e-04	184	190	6	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	facs-Skin-Skin_Anagen-18m-Mesenchymal-nan\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDGFRB RIMKLA PLXND1 RUSC2 PCOLCE2 GFPT2	1.40e-04	184	190	6	96a8a0a190bc293655fe7d80cbed8119c0da25f2
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZAN ADGRV1 FREM1 FAT1 LOXHD1 HYDIN	1.40e-04	184	190	6	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Skin-Skin_Anagen-18m-Mesenchymal\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDGFRB RIMKLA PLXND1 RUSC2 PCOLCE2 GFPT2	1.40e-04	184	190	6	780eb72da43527f0c72effac3423ec7384f05f20
ToppCell	3'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-venous_capillary\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL15A1 UACA PLXND1 LOXHD1 KCNC4 NOS3	1.44e-04	185	190	6	a987dbf6adf533c5f8a0a8a465a6c8e67e0ffcc8
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ADCY4 COL15A1 UACA IER5 PLXND1 LOXHD1	1.44e-04	185	190	6	602536a3308a848f106adcb0a83530997440c8f4
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L3-4_RORB_RPS3P6\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	COL6A1 PDGFRB ADGRV1 PXDNL EFCAB12 TANC1	1.44e-04	185	190	6	10da5c2a92bfb3248d3f6f94a0933996326cf590
ToppCell	COVID-19-Heart-Fib_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	COL6A1 COL15A1 PXDN PXDNL PCOLCE2 GFPT2	1.44e-04	185	190	6	8f95d8e591bf7379d13f5a0545b0cb49e2b1ab5d
ToppCell	10x3'2.3-week_12-13-Mesenchymal_myocytic-stroma-muscle\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	COL15A1 FAT1 DQX1 PCOLCE2 BSCL2 TANC1	1.44e-04	185	190	6	0094f9baddb20214d2a2c166f1637d1a9cf1169a
ToppCell	10x_5'_v1-Non-neoplastic-Myeloid-Mono-Mono_anti-infl-Z\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	COL6A1 ITSN1 PLXND1 LPIN3 PCOLCE2 TDRD6	1.48e-04	186	190	6	f73cb91e74a806858650ae97f543fc779ba4cff8
ToppCell	droplet-Mammary_Gland-nan-21m-Mesenchymal-nan\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL6A1 COL15A1 PDGFRB PCOLCE2 GFPT2 ABCD2	1.48e-04	186	190	6	cc94e0c5d1665d2ea2bb871ad79d8e1ec2249fb5
ToppCell	10x_5'_v1-Non-neoplastic-Myeloid-Mono-Mono_anti-infl\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	COL6A1 ITSN1 PLXND1 LPIN3 PCOLCE2 TDRD6	1.48e-04	186	190	6	8694ca16c9780729f4fba67ba20e35745f1eb4e9
ToppCell	Globus_pallidus-Macroglia-OLIGODENDROCYTE-O1\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	KRT28 ADGRV1 PCOLCE2 MUC4 SEC14L5	1.52e-04	118	190	5	d0dd5c882cd9e0a5eb0cb08e47877292126bd4ae
ToppCell	Globus_pallidus-Macroglia-OLIGODENDROCYTE-O1-Trf\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	KRT28 ADGRV1 PCOLCE2 MUC4 SEC14L5	1.52e-04	118	190	5	4283699cb3ca7a112faa07727dfdc0b0a67fb779
ToppCell	LV-10._Endothelium_II\|World / Chamber and Cluster_Paper	TPO ADCY4 PLXND1 EPB41L4A ADD1 NOS3	1.52e-04	187	190	6	7876dcb4800c2e54874df3d933efb79307a64a97
ToppCell	facs-Trachea-3m-Endothelial\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ADCY4 SEMA7A PLXND1 CASKIN2 MCF2L NOS3	1.57e-04	188	190	6	dd817059e1b4225e84733559f7839cc973b7dfd6
ToppCell	facs-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ADCY4 SEMA7A PLXND1 CASKIN2 MCF2L NOS3	1.57e-04	188	190	6	6ab5ce8569f896a0fe7a76b8b4a83661e5499b8c
ToppCell	facs-Trachea-3m-Endothelial-endothelial_cell_of_trachea\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ADCY4 SEMA7A PLXND1 CASKIN2 MCF2L NOS3	1.57e-04	188	190	6	20072a2a3f9ecbe727c850629f19420cf60e4bc5
ToppCell	5'-Adult-Appendix-Endothelial-blood_vessel_EC-arterial_capillary\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TPO ADCY4 COL15A1 PLXND1 CASKIN2 MCF2L	1.57e-04	188	190	6	a11b12f1857953bcdbfb5f25e127f2350c39567d
ToppCell	5'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ADCY4 COL15A1 UACA PLXND1 CASKIN2 NOS3	1.62e-04	189	190	6	db09d591b885ce2bc9e353f08b6694e2192582e1
ToppCell	facs-Heart-RA-18m-Endothelial-endothelial_cell_of_coronary_artery\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADCY4 SEMA7A UACA PLXND1 MCF2L NOS3	1.62e-04	189	190	6	30dc1725d43a60017fb12d706f1f85a33de4947e
ToppCell	PBMC-Mild-cDC_12\|Mild / Compartment, Disease Groups and Clusters	ABCC11 ZWINT DHCR24 UTP20 TANC1 PLK4	1.62e-04	189	190	6	946c95d2ecc36b241f58e8c4ad6455fe47c762fa
ToppCell	droplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l10\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ADCY4 SEMA7A PLXND1 CASKIN2 MCF2L NOS3	1.62e-04	189	190	6	28b9e96a5206b7fdae9b17daf05c8f5d24b6c5ec
ToppCell	10x3'2.3-week_17-19-Mesenchymal_osteo-stroma-osteochondral_precursor\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	COL6A1 UACA PDGFRB HEPH OR51E1 FAT1	1.62e-04	189	190	6	1ff4f8da572bdc6356e9df9f41a7f62c81d4c570
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ADCY4 COL15A1 UACA HEPH CASKIN2 NOS3	1.62e-04	189	190	6	e60a3d6aa84788c29f23439f1c747431ea581bc3
Drug	Althiazide [5588-16-9]; Down 200; 10.4uM; PC3; HT_HG-U133A	COL6A1 CCDC186 SRC LRRK1 PLXND1 TMBIM1 TRIM23 BFSP1 RUSC2 ABCB8 PLK4	7.07e-07	196	187	11	4491_DN
Disease	vision disorder	TPO PXDN CCDC42	1.20e-04	16	181	3	MONDO_0021084
Disease	Chediak-Higashi syndrome (implicated_via_orthology)	WDFY3 NSMAF	2.23e-04	4	181	2	DOID:2935 (implicated_via_orthology)
Disease	Cerebrooculofacioskeletal Syndrome 1	ERCC5 ERCC6	2.23e-04	4	181	2	C0220722
Disease	Achilles tendon injury	CHAF1B MPP7	3.70e-04	5	181	2	EFO_0600078
Disease	response to placebo	TPO PXDN	3.70e-04	5	181	2	EFO_0008344
Disease	larynx cancer (is_implicated_in)	ERCC5 ERCC6	5.52e-04	6	181	2	DOID:2596 (is_implicated_in)
Disease	Fuchs' endothelial dystrophy (is_implicated_in)	LOXHD1 SLC4A11	5.52e-04	6	181	2	DOID:11555 (is_implicated_in)
Disease	Cockayne syndrome (implicated_via_orthology)	ERCC5 ERCC6	5.52e-04	6	181	2	DOID:2962 (implicated_via_orthology)
Disease	white matter hyperintensity measurement	AHCYL1 ZAN CYP20A1 EVPL ZNF106 CARF KIF2A NOS3	5.82e-04	302	181	8	EFO_0005665
Disease	antioxidant measurement	CHAF1B MYO3B MPP7	5.96e-04	27	181	3	EFO_0005119
Disease	Coronary Arteriosclerosis	PTGS2 NOS3 PCSK9 ANKS1A	6.93e-04	65	181	4	C0010054
Disease	Coronary Artery Disease	PTGS2 NOS3 PCSK9 ANKS1A	6.93e-04	65	181	4	C1956346
Disease	Cerebral ventriculomegaly	CRPPA HYDIN	7.70e-04	7	181	2	C1531647
Disease	Hydrocephalus Ex-Vacuo	CRPPA HYDIN	7.70e-04	7	181	2	C0270720
Disease	Communicating Hydrocephalus	CRPPA HYDIN	7.70e-04	7	181	2	C0009451
Disease	epidermolysis bullosa simplex (is_implicated_in)	DST PLEC	7.70e-04	7	181	2	DOID:4644 (is_implicated_in)
Disease	Headache, HOMA-B	BLK ZNF106	7.70e-04	7	181	2	EFO_0004469, HP_0002315
Disease	Fetal Cerebral Ventriculomegaly	CRPPA HYDIN	7.70e-04	7	181	2	C2936718
Disease	Post-Traumatic Hydrocephalus	CRPPA HYDIN	7.70e-04	7	181	2	C0477432
Disease	Obstructive Hydrocephalus	CRPPA HYDIN	7.70e-04	7	181	2	C0549423
Disease	Microcephaly	ERCC6 IARS1 KIF2A PLK4	7.77e-04	67	181	4	C0025958
Disease	visceral adipose tissue measurement	GRIA1 DNAJC27 ARMH2 YEATS2 STX4 MYO3B TNRC6A CRYBG1 THNSL2 ANKS1A	8.19e-04	481	181	10	EFO_0004765
Disease	Severe Congenital Microcephaly	ERCC6 KIF2A PLK4	8.99e-04	31	181	3	C3853041
Disease	Lupus Erythematosus, Systemic	PTGS2 BLK C4A C4B	9.66e-04	71	181	4	C0024141
Disease	Congenital Hydrocephalus	CRPPA HYDIN	1.02e-03	8	181	2	C0020256
Disease	Aqueductal Stenosis	CRPPA HYDIN	1.02e-03	8	181	2	C2936786
Disease	Microlissencephaly	ERCC6 KIF2A PLK4	1.08e-03	33	181	3	C1956147
Disease	brain ischemia (implicated_via_orthology)	SRC PTGS2 NOS3	1.29e-03	35	181	3	DOID:2316 (implicated_via_orthology)
Disease	Tendinopathy	CHAF1B MPP7	1.31e-03	9	181	2	EFO_1001434
Disease	Hydrocephalus	CRPPA HYDIN	1.31e-03	9	181	2	C0020255
Disease	Prostatic Neoplasms	CUL3 RGMB COL15A1 ITSN1 PTGS2 VPS52 USP7 SPEN MUC4 PCDH8 NOS3	1.55e-03	616	181	11	C0033578
Disease	Malignant neoplasm of prostate	CUL3 RGMB COL15A1 ITSN1 PTGS2 VPS52 USP7 SPEN MUC4 PCDH8 NOS3	1.55e-03	616	181	11	C0376358
Disease	Essential hypertension	ADD1 NOS3	1.63e-03	10	181	2	cv:C0085580
Disease	Essential hypertension, genetic	ADD1 NOS3	1.63e-03	10	181	2	cv:CN305331
Disease	Asthma, Occupational	PTGS2 HERC2	1.63e-03	10	181	2	C0264423
Disease	HYPERTENSION, ESSENTIAL	ADD1 NOS3	1.63e-03	10	181	2	145500
Disease	Dystonia	ERCC6 PDGFRB CHRNA4 SUOX	1.97e-03	86	181	4	C0013421
Disease	Huntington Disease, Late Onset	MAOB FAAH	2.37e-03	12	181	2	C0393574
Disease	Oligospermia	BSCL2 NOS3	2.37e-03	12	181	2	C0028960
Disease	Mouth Diseases	CHAF1B PTGS2	2.37e-03	12	181	2	C0026636
Disease	Essential Hypertension	ADD1 NOS3	2.37e-03	12	181	2	C0085580
Disease	Akinetic-Rigid Variant of Huntington Disease	MAOB FAAH	2.37e-03	12	181	2	C0751207
Disease	Juvenile Huntington Disease	MAOB FAAH	2.37e-03	12	181	2	C0751208
Disease	glioblastoma (is_marker_for)	CHAF1B RPL35A PTGS2	2.50e-03	44	181	3	DOID:3068 (is_marker_for)
Disease	very low density lipoprotein cholesterol measurement, cholesterol:total lipids ratio	PGS1 CRPPA MSRA ZNF106 HELZ2 PCSK9	2.56e-03	222	181	6	EFO_0008317, EFO_0020943
Disease	Malignant neoplasm of breast	RPL31 ERCC6 SRC MAGEE1 PKDREJ PTGS2 FAAH PHKB RGL1 ABCB8 UTP20 HERC2 SPEN PCDH8 NOS3	2.66e-03	1074	181	15	C0006142
Disease	shigellosis	CHAF1B MPP7	4.24e-03	16	181	2	EFO_0005585
Disease	atherosclerosis (is_implicated_in)	ADD1 NOS3	4.24e-03	16	181	2	DOID:1936 (is_implicated_in)
Disease	Uveal Melanoma	THNSL2 HERC2 TDP1	4.25e-03	53	181	3	EFO_1000616
Disease	mean platelet volume	ZAN AAMDC FRYL PLXND1 TNRC6A USP7 KIF28P KIF2A PLEC MCF2L NOS3 ALOX12 SEC14L5 ANKS1A	4.27e-03	1020	181	14	EFO_0004584
Disease	body mass index, osteoarthritis	SEMA7A CYP20A1 CARF	4.48e-03	54	181	3	EFO_0004340, MONDO_0005178
Disease	Eye Abnormalities	CRPPA FREM1	4.79e-03	17	181	2	C0015393
Disease	Huntington Disease	MAOB FAAH	4.79e-03	17	181	2	C0020179
Disease	Alzheimer disease, psychotic symptoms	CHAF1B MPP7	4.79e-03	17	181	2	EFO_0005940, MONDO_0004975
Disease	Mental Depression	MAOB GRIA1 PTGS2 CHRNA4 CRY1 NOS3	4.93e-03	254	181	6	C0011570
Disease	taurochenodeoxycholate measurement	CHAF1B MPP7	5.37e-03	18	181	2	EFO_0010537
Disease	Gastric ulcer	PTGS2 NOS3	5.37e-03	18	181	2	C0038358
Disease	essential hypertension (is_implicated_in)	ADD1 NOS3	5.37e-03	18	181	2	DOID:10825 (is_implicated_in)
Disease	Drug habituation	FAAH MSRA OR51E1 MPP7	5.58e-03	115	181	4	C0013170
Disease	Drug abuse	FAAH MSRA OR51E1 MPP7	5.58e-03	115	181	4	C0013146
Disease	Prescription Drug Abuse	FAAH MSRA OR51E1 MPP7	5.58e-03	115	181	4	C4316881
Disease	Substance-Related Disorders	FAAH MSRA OR51E1 MPP7	5.58e-03	115	181	4	C0236969
Disease	Drug Use Disorders	FAAH MSRA OR51E1 MPP7	5.58e-03	115	181	4	C0013222
Disease	Drug Dependence	FAAH MSRA OR51E1 MPP7	5.58e-03	115	181	4	C1510472
Disease	Substance Dependence	FAAH MSRA OR51E1 MPP7	5.58e-03	115	181	4	C0038580
Disease	Substance Use Disorders	FAAH MSRA OR51E1 MPP7	5.58e-03	115	181	4	C0038586
Disease	Organic Mental Disorders, Substance-Induced	FAAH MSRA OR51E1 MPP7	5.58e-03	115	181	4	C0029231
Disease	Substance abuse problem	FAAH MSRA OR51E1 MPP7	5.75e-03	116	181	4	C0740858
Disease	very low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio	PGS1 CRPPA MSRA ZNF106 HELZ2 PCSK9	5.93e-03	264	181	6	EFO_0008317, EFO_0020944
Disease	portal hypertension (implicated_via_orthology)	PTGS2 NOS3	5.97e-03	19	181	2	DOID:10762 (implicated_via_orthology)
Disease	hydrocephalus (implicated_via_orthology)	ADD1 HYDIN	5.97e-03	19	181	2	DOID:10908 (implicated_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
VEHILKIGYLNDRVD	NT5C3A	291	Q9H0P0
TVEYLKKHGIDVRVL	AAMDC	81	Q9H7C9
IHIYRLVSGNSIEEK	EP400	2016	Q96L91
RAVEGVQYIADHLKA	CHRNA4	566	P43681
HQLYETKEGETTRLI	CCDC186	361	Q7Z3E2
TAVITKGDRHLYIVT	CCIN	416	Q13939
IGEIKTQLRTHYDVN	CCDC7	1246	Q96M83
DLQIEVTVKGHVEYT	C4B	1396	P0C0L5
GIYKRTAVIQESESH	ABCD2	436	Q9UBJ2
TYFHEEKIVVLGQVL	ARMH2	51	H3BNL8
ARIVYIISSQKELHG	GOT1L1	126	Q8NHS2
YVIKEGESVELHIIR	ADGRV1	786	Q8WXG9
VVKTLRGHLEDVYDI	CHAF1B	121	Q13112
VKRHQGVSVLYADIV	ADCY4	266	Q8NFM4
GRHIQYAKISQIVKE	ADAD1	201	Q96M93
AAQYGHTEVVKVLLE	ANKS1A	156	Q92625
NYHISAIVEKVLIFG	ADCY10	76	Q96PN6
RHEYTVIGQKVNLAA	ADCY10	401	Q96PN6
EEIHEVIARYKTLVS	CCDC42	166	Q96M95
SIYLAGKVEEQHLRT	CCNQ	76	Q8N1B3
YHGVNLDQTVKEFIV	C2orf76	26	Q3KRA6
EVEDIVIYLSSLGKH	EFCAB12	236	Q6NXP0
EREVYLAILAGIHSK	ADNP2	836	Q6IQ32
EGAVYHVTLKRVQIQ	RGL1	21	Q9NZL6
YVKESHGKDIRVVVV	RIMKLA	191	Q8IXN7
IATEAGQLAHYTKRV	H2BW2	96	P0C1H6
KYQHKRISLVEAGVT	CRPPA	111	A4D126
EKTGHAEVVRVVYQP	MSRA	111	Q9UJ68
KRIHGVNEKISVQAY	PM20D1	461	Q6GTS8
GLETYKVNEVERLIH	MAOB	76	P27338
KIEYIHQETATVLGT	EXO5	291	Q9H790
NIDSRYDGINHVIVK	ERCC6	1011	P0DP91
GHLRTYKEVVVSVPQ	NUP210	1541	Q8TEM1
KVDTEVGHVIRYVTA	FAT1	2091	Q14517
IGLHTREVSKNYEQA	MUC4	4931	Q99102
HKSTYERLGEVVELL	LPIN3	801	Q9BQK8
QVRTETEGQKLEYEH	KRT28	361	Q7Z3Y7
TVKLGEKLERYHTAI	LAD1	401	O00515
AYDTQLVLGNRKHTI	TMBIM1	266	Q969X1
ARTLNHVYGTELVVL	MAGEE1	791	Q9HCI5
EHINIKLSDYGISRQ	LRRK1	1401	Q38SD2
IDYGVTKVHVRDREI	DNAJC27	51	Q9NZQ0
LIKTHQEQGRSYKEV	HERC2	1491	O95714
RLDHDNIVKVYEVLG	MAPK4	71	P31152
EDVISHKGDLRYITI	DST	3971	Q03001
TVKQTRQEEIFYVGH	LIPJ	126	Q5W064
SVETDRGVKEQLHLY	NKIRAS1	46	Q9NYS0
IEHLYIVEGEKTVES	KIAA1109	1476	Q2LD37
VEVYETHARIALEKG	LENG8	621	Q96PV6
SEARGKILHYQVTLQ	IL12RB2	351	Q99665
NVGLIYKVRIEHDNT	LOXHD1	101	Q8IVV2
IHEVQKSLRNGDTVY	CARF	476	Q8N187
TKEYHVVVSGDTIKL	FAM135A	741	Q9P2D6
GTYVVVLKEETHLSQ	PCSK9	76	Q8NBP7
LGLQSHEYRVKIGQV	PLXND1	1206	Q9Y4D7
LKITTIVVHIYEDGI	PDC	131	P20941
VLGNLTIIYIVRTEH	OR51E1	41	Q8TCB6
VIYGVRTKHIRETVL	OR52E6	291	Q96RD3
TVGLQSVYEKVLHRD	PCDH8	1011	O95206
RFNETIGLQHIKVYL	PGS1	211	Q32NB8
HITIGTVLQIKVYRD	PDZD9	96	Q8IXQ8
DAVYQEARKVVGALH	TPO	431	P07202
YHAVGDQLDLREKVV	EVPL	731	Q92817
YAHKLEVQRTDGVLS	FRYL	1241	O94915
GVSRHLVVKETEVAY	FREM1	646	Q5H8C1
LKVRYQHDGTEVLQD	FREM1	846	Q5H8C1
QRDVISEAVTYKHTG	FREM1	951	Q5H8C1
RKLLISDTQHYGVTV	MPP7	386	Q5T2T1
LRGKTVVLVTHQLQY	ABCC11	681	Q96J66
HKVGTVVTPDNDIYI	KBTBD2	306	Q8IY47
QRTHTYIVTPGRDKE	MEX3D	301	Q86XN8
TIKIVIEDYVQHLSG	PTGS2	326	P35354
REDKHLIGTVRYASI	CSNK1A1L	176	Q8N752
SLHATVSIINIYKEG	PCOLCE2	331	Q9UKZ9
EGIVHLFYQRDDIVK	ALOX12	476	P18054
GAISSEEIIKYAHRI	MED4	141	Q9NPJ6
VTIVDTVTLQYLGKH	MFSD6	306	Q6ZSS7
LSEAEKVYIVHGVQE	EXOSC7	6	Q15024
KVYIVHGVQEDLRVD	EXOSC7	11	Q15024
IQGALHSYKEIIIEA	EXOC8	551	Q8IYI6
EYVGKRIVDLQHTEV	NATD1	46	Q8N6N6
HEAALYGKTEVVRLL	CASKIN2	226	Q8WXE0
IQHVIDSGLELRSVY	DQX1	336	Q8TE96
GEIHLTVAVLAYRTQ	NOS3	951	P29474
TLIKAYGIRIDVIVH	P2RX2	316	Q9UBL9
IGIYVEIKRSDGRIH	KIF2A	11	O00139
IAVVVVYLIHIGRSK	OTOP1	326	Q7RTM1
ARKIVGAELQHITYS	PXDNL	1001	A1KZ92
VQGDVLIVIYHARST	GAK	636	O14976
FGYIILGEVRTHIIK	HYDIN	1601	Q4G0P3
SGHVEYQILVVTRLA	HS1BP3	36	Q53T59
RIGIINYSHKVEKVA	COL28A1	836	Q2UY09
VVIHNGIITNYKDLR	GFPT2	116	O94808
LHYSDEVEIIQGLTR	COL6A1	91	P12109
VQHTYRTGVKVDKAT	ARHGDIB	126	P52566
GETLRKLYEQHHVVQ	DHCR24	371	Q15392
IDKRYVESQRHTIQG	FMO5	416	P49326
DVTTQGELIKHYKIR	BLK	166	P51451
EKLYTGLREVVTEHL	CUL3	71	Q13618
TKERHVLVTGDANYV	BFSP1	466	Q12934
VHREVIFKYLATQGI	C3orf38	66	Q5JPI3
RKRQGYIHELIVTEE	ITSN1	1236	Q15811
GVEVIVRISHTLYDL	CRY1	121	Q16526
EQLIGNKHYAVDSIR	MCF2L	416	O15068
YKIHKEAVTGITVSR	NSMAF	626	Q92636
HHVRILGTKIYTEQQ	CCDC196	256	A0A1B0GTZ2
ELQHEIEVYRKTVIA	FAAH	446	O00519
KPVVIGSIRHVVQDY	CRYBG1	1106	Q9Y4K1
HLLSVEGQVIETKYE	CYP20A1	431	Q6UW02
ILSDTYTVEKVEVHR	HAUS4	286	Q9H6D7
NEKGRRTNYTLHVIE	GRIA1	356	P42261
ITKVLQKYHTELGRV	HELZ2	1316	Q9BYK8
TGAIIEIHSKRIQLY	BSCL2	196	Q96G97
QKAHLVIEGTFIYLR	COL15A1	1146	P39059
YTKIETQGDPIRIRH	EPB41L4A	576	Q9HCS5
QYTANVKRGKEVIEH	SEC14L5	151	O43304
HLGTEDIISTKQYVE	SACS	3841	Q9NZJ4
KEEVYRHEEGITVIS	PKD1L1	1436	Q8TDX9
LKQICREDGHTYVEV	HELB	301	Q8NG08
RGYDLQKEVLVKVTH	KIF28P	571	B7ZC32
DLQIEVTVKGHVEYT	C4A	1396	P0C0L4
ITKEGTVSDHIERVY	PHKB	756	Q93100
LTLVRVKVAEAGHYT	PDGFRB	381	P09619
QLVEVVAKYTRDHVG	ABCB8	171	Q9NUT2
LDEIHTEVSKYLGRV	FBXL21P	411	Q9UKT6
HRDVVELLIKYGADV	GABPB2	116	Q8TAK5
EAHRIVSISLGKIYN	IER5	6	Q5VY09
EDQKILTLTEYRLHG	RUSC2	836	Q8N2Y8
IDHYVGIARDQTKSI	RTN3	1001	O95197
KELQTTLVRGYQVHV	UTP20	1886	O75691
QREHTALLKIEGVYA	RPL35A	21	P18077
KSLRIVERESGHYVE	RGMB	256	Q6NW40
GHIYDTIVNVKETRL	SLC4A11	726	Q8NBS3
RHEKLVQLYAVVSEE	SRC	321	P12931
THTRGIYQKAIEVLS	XAB2	646	Q9HCS7
IRHQDVYSTVLGVVL	TREML2	261	Q5T2D2
AQVLHVDYGRKELVS	TDRD6	341	O60522
HVDYVVDQVVGKLIE	TOP2B	346	Q02880
GVEIRTIYAAHKQAK	SYNJ1	186	O43426
EHLRITVGVDGTLYK	HKDC1	851	Q2TB90
EDGRNQEVHTLIKYT	PUS7L	81	Q9H0K6
IVEESVTGVHRLYQL	AHCYL1	251	O43865
ENVHIYLIGKESSRT	KBTBD4	236	Q9NVX7
YKIIVSDLHSVGEIS	PKDREJ	596	Q9NTG1
NVTRKDAGTYTLHII	PSG9	111	Q00887
TGKVRQYFIEAHEIQ	HEPH	376	Q9BQS7
VVSEDTSHYILIKGI	ERCC5	281	P28715
LTSVHAVYKVETIGD	GUCY1B2	426	O75343
AQELKYGDIVERHLI	POLR3A	441	O14802
YFLEKREKHVTVVVG	THNSL2	126	Q86YJ6
TVLYLVEKGAVIEHV	TANC1	1226	Q9C0D5
AGTIKDIVTRYAHQS	IARS1	61	P41252
YVERGQEHVKTALEN	STX4	251	Q12846
VYRAESIHTGLEVAI	PLK4	26	O00444
ERLVAVLQGKHSTYD	AARS2	271	Q5JTZ9
IEKEYQPHVIVSTTG	ADD1	546	P35611
LGREVQVEHIKAYVT	CMBL	21	Q96DG6
VYRHLKDLEEGIQTL	GH2	136	P01242
TGVDLRHYSKQVELE	VPS52	76	Q8N1B4
TLVREINKHTSPEEY	VWDE	676	Q8N2E2
YEEGLRVVIHTSNLI	TDP1	271	Q9NUW8
ATYREHVEAIKIGLT	ZWINT	101	O95229
LIEHQRIHSGEKTYE	ZNF197	861	O14709
IKKLTGITERYDQSH	ZNF761	116	Q86XN6
YVLTRDGRVHALQEK	VPS11	341	Q9H270
DSYKLIIHQRVHTGE	ZNF749	651	O43361
TISRHGLSVNVVKYI	WDFY3	241	Q8IZQ1
VTREYTINIHKRIHG	RPL31	21	P62899
IYVTKEHLQETDVVR	TCEANC	36	Q8N8B7
EEKIGIDIDHTQSYR	SPEN	1156	Q96T58
HLLEVDRKTGAVYVA	NHLRC3	311	Q5JS37
LVKQDGSTIHIRYRE	MRPL55	56	Q7Z7F7
THIAVRTGKILEYNN	MEX3A	286	A1L020
YETRKIVGAEIQHIT	PXDN	1016	Q92626
VLYLTTDRGTIHKVV	SEMA7A	426	O75326
VVVAVAYAIVGHLIK	SMIM44	46	A0A286YF18
NQRLYVHEAVKAGVV	PLEC	3541	Q15149
YVDISRGKHERLVVV	TBCK	56	Q8TEA7
ANYRKGQEEIVTLHA	UACA	951	Q9BZF9
VLYHIEELSGVRTAV	ZDHHC5	171	Q9C0B5
KISEEVHSYKVRVGR	ZNF655	61	Q8N720
SHVRELLAQYKIGEL	SUOX	146	P51687
DYSRKLVGIVQHIEG	TRIM23	246	P36406
YKLRHIVDEVNGLIS	EFTUD2	276	Q15029
REYKSVKERGVHIVS	TOPBP1	956	Q92547
LLEIVSYKIIGVHQE	USP7	941	Q93009
ATYDTTLVEKEGIHV	PTP4A1	51	Q93096
ELVRIYKGHNHAVTV	ZNF106	1731	Q9H2Y7
HGNALVRYSSKEEVV	TNRC6A	1816	Q8NDV7
IDIIHNLKLDRTYTG	YEATS2	301	Q9ULM3
YDAQVTLQKGHRVLI	ZAN	1996	Q9Y493
EKIIINVGGTRHETY	KCNC4	36	Q03721
HAYGIISISRVDKLE	JKAMP	261	Q9P055
KTVEYLHSQGVVHRD	RPS6KA1	521	Q15418
DKEVHSVYRILAGIL	MYO3B	596	Q8WXR4