Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcesslong-chain fatty-acyl-CoA catabolic process

ACOT1 ACOT2

1.59e-053482GO:0036116
DomainBile_Hydr_Trans

ACOT1 ACOT2

3.55e-054462PF04775
DomainThio_Ohase/aa_AcTrfase

ACOT1 ACOT2

3.55e-054462IPR006862
DomainAcyl-CoA_thioEstase_long-chain

ACOT1 ACOT2

3.55e-054462IPR016662
DomainBAAT_C

ACOT1 ACOT2

5.91e-055462IPR014940
DomainBAAT_C

ACOT1 ACOT2

5.91e-055462PF08840
DomainbZIP_1

CREB3L4 ATF6B CREB3L1

7.93e-0534463PF00170
DomainTF_DNA-bd

CREB3L4 ATF6B CREB3L1

1.02e-0437463IPR008917
DomainBRLZ

CREB3L4 ATF6B CREB3L1

2.84e-0452463SM00338
DomainBZIP

CREB3L4 ATF6B CREB3L1

3.00e-0453463PS50217
DomainbZIP

CREB3L4 ATF6B CREB3L1

3.18e-0454463IPR004827
DomainS_TKc

PIM2 CDK13 SCYL3 MAP3K14 DAPK1

1.83e-03359465SM00220
DomainPkinase

PIM2 CDK13 SCYL3 MAP3K14 DAPK1

2.37e-03381465PF00069
DomainWW

WWTR1 WWC1

5.98e-0347462PF00397
DomainWW

WWTR1 WWC1

6.23e-0348462SM00456
Domain-

KCNH6 GGCX

6.23e-03484622.60.120.10
DomainProt_kinase_dom

PIM2 CDK13 SCYL3 MAP3K14 DAPK1

6.83e-03489465IPR000719
DomainWW_DOMAIN_2

WWTR1 WWC1

7.01e-0351462PS50020
DomainRmlC-like_jellyroll

KCNH6 GGCX

7.01e-0351462IPR014710
DomainWW_DOMAIN_1

WWTR1 WWC1

7.01e-0351462PS01159
DomainPROTEIN_KINASE_DOM

PIM2 CDK13 SCYL3 MAP3K14 DAPK1

7.06e-03493465PS50011
DomainWW_dom

WWTR1 WWC1

7.28e-0352462IPR001202
DomainBZIP_BASIC

ATF6B CREB3L1

7.55e-0353462PS00036
DomainKinase-like_dom

PIM2 CDK13 SCYL3 MAP3K14 DAPK1

1.04e-02542465IPR011009
DomainSer/Thr_kinase_AS

PIM2 CDK13 MAP3K14 DAPK1

1.14e-02357464IPR008271
DomainPROTEIN_KINASE_ST

PIM2 CDK13 MAP3K14 DAPK1

1.19e-02362464PS00108
PathwayKEGG_MEDICUS_PATHOGEN_HBV_HBX_TO_CREB_MEDIATED_TRANSCRIPTION

CREB3L4 ATF6B CREB3L1

3.94e-0613353M47595
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_CREB_MEDIATED_TRANSCRIPTION

CREB3L4 ATF6B CREB3L1

3.94e-0613353M47674
PathwayKEGG_MEDICUS_REFERENCE_DRD1_GNAS_AC_PKA_SIGNALING_PATHWAY

CREB3L4 ATF6B CREB3L1

7.68e-0616353M47551
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_PRKACA_TO_ACTH_CORTISOL_SIGNALING_PATHWAY

CREB3L4 ATF6B CREB3L1

9.31e-0617353M47514
PathwayKEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PRKAR1A_TO_ACTH_CORTISOL_SIGNALING_PATHWAY

CREB3L4 ATF6B CREB3L1

1.12e-0518353M47516
PathwayKEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PDE11A_PDE8B_TO_ACTH_CORTISOL_SIGNALING_PATHWAY

CREB3L4 ATF6B CREB3L1

1.55e-0520353M47517
PathwayKEGG_MEDICUS_REFERENCE_ACH_CHRN_RAS_ERK_SIGNALING_PATHWAY

CREB3L4 ATF6B CREB3L1

1.81e-0521353M47792
PathwayKEGG_MEDICUS_REFERENCE_E2_ER_RAS_ERK_SIGNALING_PATHWAY

CREB3L4 ATF6B CREB3L1

2.40e-0523353M47799
PathwayKEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_ATP2B3_TO_ANGIOTENSIN_ALDOSTERONE_SIGNALING_PATHWAY

CREB3L4 ATF6B CREB3L1

2.40e-0523353M47512
PathwayKEGG_MEDICUS_REFERENCE_TNF_P38_SIGNALING_PATHWAY

CREB3L4 ATF6B CREB3L1

2.74e-0524353M47568
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_GNAS_TO_CRHR_PKA_ACTH_SIGNALING_PATHWAY

CREB3L4 ATF6B CREB3L1

2.74e-0524353M47520
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_CACNA1D_H_TO_ANGIOTENSIN_ALDOSTERONE_SIGNALING_PATHWAY

CREB3L4 ATF6B CREB3L1

2.74e-0524353M47509
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_KCNJ5_TO_ANGIOTENSIN_ALDOSTERONE_SIGNALING_PATHWAY

CREB3L4 ATF6B CREB3L1

3.11e-0525353M47510
PathwayKEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_ATP1A1_TO_ANGIOTENSIN_ALDOSTERONE_SIGNALING_PATHWAY

CREB3L4 ATF6B CREB3L1

3.11e-0525353M47511
PathwayKEGG_MEDICUS_PATHOGEN_HCMV_UL33_TO_GNAI_AC_PKA_SIGNALING_PATHWAY

CREB3L4 ATF6B CREB3L1

3.51e-0526353M47553
PathwayKEGG_MEDICUS_REFERENCE_CRHR_PKA_ACTH_SIGNALING_PATHWAY

CREB3L4 ATF6B CREB3L1

3.94e-0527353M47518
PathwayKEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_RASD1_TO_CRHR_PKA_ACTH_SIGNALING_PATHWAY

CREB3L4 ATF6B CREB3L1

3.94e-0527353M47519
PathwayKEGG_MEDICUS_REFERENCE_GHRHR_PKA_GH_SIGNALING_PATHWAY

CREB3L4 ATF6B CREB3L1

4.40e-0528353M47647
PathwayKEGG_MEDICUS_REFERENCE_ANGIOTENSIN_ALDOSTERONE_SIGNALING_PATHWAY

CREB3L4 ATF6B CREB3L1

4.40e-0528353M47508
PathwayKEGG_MEDICUS_REFERENCE_PRNP_PI3K_NOX2_SIGNALING_PATHWAY

CREB3L4 ATF6B CREB3L1

4.90e-0529353M47764
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_GNAS_TO_ACTH_CORTISOL_SIGNALING_PATHWAY

CREB3L4 ATF6B CREB3L1

4.90e-0529353M47515
PathwayKEGG_MEDICUS_REFERENCE_TSH_TG_SIGNALING_PATHWAY

CREB3L4 ATF6B CREB3L1

4.90e-0529353M47627
PathwayKEGG_MEDICUS_VARIANT_CYP11B1_CYP11B2_FUSION_TO_ACTH_CORTISOL_SIGNALING_PATHWAY

CREB3L4 ATF6B CREB3L1

6.01e-0531353M47507
PathwayKEGG_MEDICUS_REFERENCE_ACTH_CORTISOL_SIGNALING_PATHWAY

CREB3L4 ATF6B CREB3L1

6.62e-0532353M47506
PathwayKEGG_MEDICUS_PATHOGEN_HCMV_UL33_TO_GNB_G_RHO_SIGNALING_PATHWAY

CREB3L4 ATF6B CREB3L1

7.27e-0533353M47550
PathwayWP_RENINANGIOTENSINALDOSTERONE_SYSTEM_RAAS

CREB3L4 ATF6B CREB3L1

1.73e-0444353M39845
PathwayREACTOME_CREB3_FACTORS_ACTIVATE_GENES

CREB3L4 CREB3L1

2.13e-049352M27773
PathwayWP_CHOLESTEROL_METABOLISM_WITH_BLOCH_AND_KANDUTSCHRUSSELL_PATHWAYS

NR1H3 ACOT1 ACOT2

2.85e-0452353MM15920
PathwayWP_G1_TO_S_CELL_CYCLE_CONTROL

CREB3L4 ATF6B CREB3L1

5.27e-0464353M39627
PathwayWP_OMEGA9_FATTY_ACID_SYNTHESIS

ACOT1 ACOT2

5.35e-0414352MM15840
PathwayWP_OMEGA3_OMEGA6_FATTY_ACID_SYNTHESIS

ACOT1 ACOT2

6.16e-0415352M39789
PathwayWP_OMEGA3_OMEGA6_FATTY_ACID_SYNTHESIS

ACOT1 ACOT2

7.03e-0416352MM15813
PathwayREACTOME_SIGNALING_BY_HIPPO

WWTR1 WWC1

1.11e-0320352MM14813
PathwayREACTOME_SIGNALING_BY_HIPPO

WWTR1 WWC1

1.11e-0320352M591
PathwayKEGG_BIOSYNTHESIS_OF_UNSATURATED_FATTY_ACIDS

ACOT1 ACOT2

1.34e-0322352M11673
PathwayWP_LDL_INFLUENCE_ON_CD14_AND_TLR4

CREB3L4 CREB3L1

1.47e-0323352M45556
PathwayREACTOME_UNFOLDED_PROTEIN_RESPONSE_UPR

CREB3L4 ATF6B CREB3L1

1.56e-0393353M10294
PathwayWP_7OXOC_AND_7BETAHC_PATHWAYS

ACOT1 ACOT2

2.02e-0327352M40054
PathwayWP_CHOLESTEROL_BIOSYNTHESIS_PATHWAY_IN_HEPATOCYTES

NR1H3 ACOT1 ACOT2

2.59e-03111353M48065
PathwayREACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION

ACOT1 ACOT2

3.38e-0335352MM15462
PathwayREACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION

ACOT1 ACOT2

3.78e-0337352M14690
Pubmed

Acyl-CoA thioesterases belong to a novel gene family of peroxisome proliferator-regulated enzymes involved in lipid metabolism.

ACOT1 ACOT2

1.94e-06249211330065
Pubmed

Acyl-CoA thioesterase-2 facilitates mitochondrial fatty acid oxidation in the liver.

ACOT1 ACOT2

1.94e-06249225114170
Pubmed

Acyl-Coa Thioesterases: A Rheostat That Controls Activated Fatty Acids Modulates Dengue Virus Serotype 2 Replication.

ACOT1 ACOT2

5.83e-06349235215835
Pubmed

Peroxisome proliferator-induced long chain acyl-CoA thioesterases comprise a highly conserved novel multi-gene family involved in lipid metabolism.

ACOT1 ACOT2

5.83e-06349210567408
Pubmed

Up-Regulated MicroRNA-27b Promotes Adipocyte Differentiation via Induction of Acyl-CoA Thioesterase 2 Expression.

ACOT1 ACOT2

5.83e-06349231930115
Pubmed

Molecular cloning and characterization of two mouse peroxisome proliferator-activated receptor alpha (PPARalpha)-regulated peroxisomal acyl-CoA thioesterases.

ACOT1 ACOT2

1.16e-05449215007068
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

UBR5 CEP72 SIPA1L3 POFUT1 PCNT

1.64e-0522549512168954
Pubmed

Analysis of the mouse and human acyl-CoA thioesterase (ACOT) gene clusters shows that convergent, functional evolution results in a reduced number of human peroxisomal ACOTs.

ACOT1 ACOT2

1.94e-05549216940157
Pubmed

CREB4, a transmembrane bZip transcription factor and potential new substrate for regulation and cleavage by S1P.

CREB3L4 CREB3L1

1.94e-05549216236796
Pubmed

Multiple mitochondrial thioesterases have distinct tissue and substrate specificity and CoA regulation, suggesting unique functional roles.

ACOT1 ACOT2

1.94e-05549231676684
Pubmed

A revised nomenclature for mammalian acyl-CoA thioesterases/hydrolases.

ACOT1 ACOT2

6.96e-05949216103133
Pubmed

Dchs1-Fat4 regulation of osteogenic differentiation in mouse.

WWTR1 MESP1

1.06e-041149231358536
Pubmed

Hippo/Mst signalling couples metabolic state and immune function of CD8α+ dendritic cells.

MAP3K14 WWTR1

1.06e-041149229849151
Pubmed

WWC proteins mediate LATS1/2 activation by Hippo kinases and imply a tumor suppression strategy.

WWTR1 WWC1

1.27e-041249235429439
Pubmed

Transcription factors, cAMP-responsive element modulator (CREM) and Tisp40, act in concert in postmeiotic transcriptional regulation.

DAPK1 CREB3L4

1.27e-041249216595651
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

CDK13 PCNX4 SIPA1L3 TBC1D25 POFUT1 PPP6R1 ATG2A PCNT

1.44e-04110549835748872
Pubmed

A regulatory T cell Notch4-GDF15 axis licenses tissue inflammation in asthma.

WWTR1 POFUT1

1.50e-041349232929274
Pubmed

Knockout of SRC-1 and SRC-3 in Mice Decreases Cardiomyocyte Proliferation and Causes a Noncompaction Cardiomyopathy Phenotype.

DTNA WWTR1

2.02e-041549226221073
Pubmed

Interactomes of Glycogen Synthase Kinase-3 Isoforms.

UBR5 SIPA1L3 PPP6R1 WWC1

2.17e-0420949436779422
Pubmed

Phosphoproteome analysis of the human mitotic spindle.

UBR5 KMT2A NSL1 PCNT

2.21e-0421049416565220
Pubmed

A census of human transcription factors: function, expression and evolution.

KMT2A SIX5 NR1H3 MESP1 CREB3L4 ATF6B CREB3L1

2.67e-0490849719274049
Pubmed

FEZ1 dimerization and interaction with transcription regulatory proteins involves its coiled-coil region.

TBC1D25 WWC1

2.93e-041849216484223
Pubmed

Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.

KCNH6 SIX5 ACOT1 ACOT2

3.28e-0423349437704626
Pubmed

An Ideal PPAR Response Element Bound to and Activated by PPARα.

ACOT1 ACOT2

3.64e-042049226241474
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

UBR5 CEP72 SIPA1L3 PPP6R1 WWC1

4.06e-0444649524255178
Pubmed

The proteomic reactor facilitates the analysis of affinity-purified proteins by mass spectrometry: application for identifying ubiquitinated proteins in human cells.

HTR1A KMT2A

4.83e-042349217203973
Pubmed

Pofut1 is required for the proper localization of the Notch receptor during mouse development.

POFUT1 MESP1

4.83e-042349218547789
Pubmed

Oncogenic functions of protein kinase D2 and D3 in regulating multiple cancer-related pathways in breast cancer.

GVINP1 UBR5 SLC4A3

5.96e-0411649330652415
Pubmed

PARD3 dysfunction in conjunction with dynamic HIPPO signaling drives cortical enlargement with massive heterotopia.

WWTR1 PCNT

6.18e-042649229899142
Pubmed

Rebalancing gene haploinsufficiency in vivo by targeting chromatin.

KMT2A MESP1

7.18e-042849227256596
Pubmed

The phosphorylation status of T522 modulates tissue-specific functions of SIRT1 in energy metabolism in mice.

ACOT1 ACOT2

7.71e-042949228364022
Pubmed

Decreased Activity of the Ghrhr and Gh Promoters Causes Dominantly Inherited GH Deficiency in Humanized GH1 Mouse Models.

CREB3L4 CREB3L1

7.71e-042949231436800
Pubmed

A transcript map of a 2-Mb BAC contig in the proximal portion of the mouse X chromosome and regional mapping of the scurfy mutation.

PIM2 TBC1D25

1.06e-033449210857745
Pubmed

Large-scale identification of mammalian proteins localized to nuclear sub-compartments.

KMT2A PCNT

1.32e-033849211555636
GeneFamilyBasic leucine zipper proteins

CREB3L4 ATF6B CREB3L1

9.64e-0549333506
GeneFamilyAcyl-CoA thioesterases

ACOT1 ACOT2

1.44e-041033241
ToppCellSevere_COVID-19-Myeloid-TRAM3|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）

HLA-DMB DTNA WWTR1 ACOT1 ACOT2 SPOCD1

6.50e-0819149605867b96199a46a415848409130697c810d18937
ToppCellBAL-Severe-Myeloid-TRAM-TRAM3|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

HLA-DMB DTNA WWTR1 ACOT1 ACOT2 SPOCD1

6.50e-081914962b10a73c5d80e83d67a7121fb004a1aa86a537ef
ToppCellBAL-Severe-Myeloid-TRAM-TRAM3-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

HLA-DMB DTNA WWTR1 ACOT1 ACOT2 SPOCD1

6.50e-0819149602e1ae144da7274171e055356d10e8d175c5347f
ToppCellBAL-Severe-Myeloid-TRAM-TRAM3|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

HLA-DMB DTNA WWTR1 ACOT1 ACOT2 SPOCD1

6.70e-0819249634505a13b8a47c9286c560122fa7861b9c331a08
ToppCellBAL-Severe-Myeloid-TRAM-TRAM3-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

HLA-DMB DTNA WWTR1 ACOT1 ACOT2 SPOCD1

6.70e-0819249657c1410ebf90c230993e065eb78385daa3360960
ToppCellSevere-Myeloid-Macrophages-FABP4+|Severe / Condition, Lineage, Cell class and cell subclass

HLA-DMB NR1H3 WWTR1 ACOT2 SPOCD1

2.20e-0619249530aad927ad40d8abaf9d0539bf8cb9d88d16f24d
ToppCellParenchymal-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DUOXA1 EXPH5 SIPA1L3 DAPK1 WWC1

2.62e-061994955cea0d9e261903e0eaad60c28a07dff72ce65027
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L6_IT-L6_IT_ALM_Tgfb1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SPTBN5 IGFN1 ACOT1 SEMA4A

1.96e-0514549484d50a13b48d50c16e768422908e371a55972d0e
ToppCellCOVID-19-Heart-CM_5_(RYR2-)|Heart / Disease (COVID-19 only), tissue and cell type

IGFN1 KLHL40 GGCX PCNT

2.54e-05155494d7e26696fd9c0a759524f331243db43059b33ed9
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-immature_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIM2 HLA-DMB SLC4A3 WWC1

3.91e-05173494e944ea3a0a368f856efacbda4600605cf751dd9c
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-immature_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIM2 HLA-DMB SLC4A3 WWC1

3.91e-0517349485fa5918e9c1f6bb4757e3350cfc71ee75c55640
ToppCell10x5'-bone_marrow-Myeloid_Mac-Intestinal_macrophages|bone_marrow / Manually curated celltypes from each tissue

SPTBN5 DAPK1 NR1H3 SEMA4A

4.00e-051744940746344d62aa7ab77c378e9d5a9f9238e741a76b
ToppCellfacs-Trachea-24m-Mesenchymal-fibroblast-fibroblast_of_trachea-|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PIM2 DTNA SIX5 ACOT1

4.09e-05175494bb898796662b97f7459b7dda7cecf6a9bde8b055
ToppCellFrontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Nptxr-Excitatory_Neuron.Slc17a7.Nptxr-Drd1_(Deep_layer_pyramidal_cells)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

CDK13 EXPH5 SCYL3 POFUT1

4.18e-051764943c76a5c4ca2b378667cb155fbb9675519572b35d
ToppCell10x3'2.3-week_17-19-Hematopoietic-HSC/MPP_and_pro-pDC_progenitor|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

SIX5 LINC00311 MESP1 SLC4A3

4.37e-05178494dff7a59e53a7329212689ca234931ed4a1b67eee
ToppCell3'_v3-bone_marrow-Myeloid_Dendritic-DC2|bone_marrow / Manually curated celltypes from each tissue

HLA-DMB DTNA SEMA4A SLC4A3

4.86e-05183494f482e4fe011fa450a475034b1e25587233855bdb
ToppCellfacs-Skin-nan-24m-Mesenchymal|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CORO2B DTNA DAPK1 CREB3L1

5.07e-051854948433a337625ff8398520e223ef92bf9bb0beb14c
ToppCellfacs-Skin-nan-24m-Mesenchymal-fibroblast|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CORO2B DTNA DAPK1 CREB3L1

5.07e-05185494049d793d043d5d434f143025de49dd210d18756c
ToppCellfacs-Skin-nan-24m-Mesenchymal-nan|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CORO2B DTNA DAPK1 CREB3L1

5.07e-0518549463200c42565eea596f9b00728e70e544b8d50a7f
ToppCellEpithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|World / Lineage, Cell type, age group and donor

DUOXA1 DAPK1 WWTR1 WWC1

5.29e-0518749481cc8435b2704a9a8287b3f54acaae0f11dd4ac7
ToppCell10x5'-blood-Myeloid_Dendritic-DC2|blood / Manually curated celltypes from each tissue

HLA-DMB DTNA SEMA4A SLC4A3

5.29e-05187494ab9c9930341527122f26fe5544c5c4818d1fd1b5
ToppCellControl-Endothelial-VE_Capillary_A|Endothelial / Disease state, Lineage and Cell class

GVINP1 DTNA EXPH5 XKR6

5.40e-0518849488b3415e33db81726dd29c1f50c886e057af50a0
ToppCellPBMC-Mild-Myeloid-cDC-cDC-cDC_5|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

HLA-DMB DTNA SEMA4A SLC4A3

5.51e-05189494c81b38cda4525254fe4fa137a4c9bc9abe0363bb
ToppCell390C-Myeloid-Macrophage-FABP4+_Macrophage_2|390C / Donor, Lineage, Cell class and subclass (all cells)

HLA-DMB ACOT1 ACOT2 SPOCD1

5.51e-051894943b5e1a8d5c1e1fa2124f64f212e9c6b8f1b7d7da
ToppCellPBMC-Mild-Myeloid-cDC-cDC-cDC_5|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

HLA-DMB DTNA SEMA4A SLC4A3

5.51e-05189494807922b5ea0faddd3abfa9ec1b53f3f2b00e61bf
ToppCellBAL-Severe-Myeloid-TRAM|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

WWTR1 ACOT1 ACOT2 SPOCD1

5.74e-051914944c4f50a502e3f6768a89df686fa2830b83b8b33f
ToppCellChildren_(3_yrs)-Epithelial|Children_(3_yrs) / Lineage, Cell type, age group and donor

DUOXA1 EXPH5 WWTR1 WWC1

5.74e-05191494e432c6e1ae82dddf84314ce73d2b7a991630d905
ToppCellBAL-Severe-Myeloid-TRAM|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

WWTR1 ACOT1 ACOT2 SPOCD1

5.74e-05191494de7c88bb46f794291025ef121a89fcd94dea4ffe
ToppCellPBMC-Severe-Myeloid-cDC-cDC-cDC_5|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

HLA-DMB DTNA SEMA4A SLC4A3

5.74e-0519149492c5a26b90a55831039220341d863cf2940f3c9b
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_5|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

HLA-DMB DTNA SEMA4A SLC4A3

5.86e-05192494dfb9101622f7d2f2c392e850cff07becfc8c655e
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_5|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

HLA-DMB DTNA SEMA4A SLC4A3

5.86e-05192494d39133cf1a20af6f2970188630fc3b27a4cfc9c5
ToppCellPBMC-Severe-Myeloid-cDC-cDC-cDC_5|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

HLA-DMB DTNA SEMA4A SLC4A3

5.86e-051924946184163dbfca882824cb266bb9030d9f79e3acb0
ToppCell390C-Myeloid-Macrophage-FABP4+_Macrophage_2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

HLA-DMB ACOT1 ACOT2 SPOCD1

5.98e-05193494c9cf5a661294a947d06d53d18d47362c0e0b6ef5
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage_2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

WWTR1 ACOT1 ACOT2 SPOCD1

5.98e-05193494aa679fb27f914a931e51cff7153861cde0edfd85
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_3|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

HLA-DMB DTNA SEMA4A SLC4A3

6.10e-05194494b16ed97eb6b7b7a220e943474c0d85c141b6e3a5
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_3|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

HLA-DMB DTNA SEMA4A SLC4A3

6.10e-051944942210f0755882d8f04edb4c109fb17c3f9149f6f7
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MAP3K14 DAPK1 WWTR1 WWC1

6.10e-0519449446070fbb0ee0eb9e1801c43b73a15707471056dc
ToppCellCOVID-19-Myeloid-TRAM2|Myeloid / Condition, Lineage and Cell class

DTNA WWTR1 ACOT2 SPOCD1

6.10e-051944944060a60c0271e7397b07993a1ef47b3291bba6e3
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MAP3K14 DAPK1 WWTR1 WWC1

6.10e-05194494abacb6a8d7a9003f2f6c2be0305507f1c1c50347
ToppCell3'-Adult-Appendix-Endothelial-blood_vessel_EC-Mature_venous_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PIM2 DBF4B DAPK1 WWTR1

6.22e-051954946a0460d949ccda7c9fe76870d3ee6c2f60677d61
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Dendritic|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

HLA-DMB DTNA SEMA4A SLC4A3

6.22e-051954944cbc36fb3ef9aef61367d3b37070a9a85fae1418
ToppCell390C-Myeloid-Macrophage|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

HLA-DMB ACOT1 ACOT2 SPOCD1

6.22e-05195494ba494be431916d43c1d480f65bed674c0722c710
ToppCellCOVID-19_Severe-cDC|COVID-19_Severe / disease group, cell group and cell class

HLA-DMB DTNA SEMA4A SLC4A3

6.22e-051954946419090b19de7b5d5140eaecf231860273da2c0d
ToppCell(010)_cDC|World / immune cells in Peripheral Blood (logTPM normalization)

HLA-DMB DTNA SEMA4A SLC4A3

6.22e-051954944aabb3f5ce70100e4d98d7fa9f8d12e84fb9fe3d
ToppCellPBMC-Control-Myeloid-cDC-cDC|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

HLA-DMB DTNA SEMA4A SLC4A3

6.35e-05196494553c22c7d48f3b4f6f2b2f10d6e668c5ebb09e8c
ToppCellPBMC-Control-Myeloid-cDC|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

HLA-DMB DTNA SEMA4A SLC4A3

6.35e-05196494e1f763fa9c11bf5f4d80e79f70f9485724ac23fe
ToppCellPBMC-Mild-Myeloid-cDC-cDC-cDC_1|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

HLA-DMB DTNA SEMA4A SLC4A3

6.35e-051964940bac14c018487ca67e7f9255b5f186e7ae665774
ToppCellPBMC-Control-Myeloid-cDC|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

HLA-DMB DTNA SEMA4A SLC4A3

6.35e-05196494d376168e15ec1cf618723259966c76be3698b9b0
ToppCellPBMC-Mild-Myeloid-cDC-cDC-cDC_1|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

HLA-DMB DTNA SEMA4A SLC4A3

6.35e-0519649433345338c825484960daa1ed82a19df38ccfc5c0
ToppCellControl-Myeloid-cDC|Control / Disease group, lineage and cell class

HLA-DMB DTNA SEMA4A SLC4A3

6.35e-0519649485d92bc226cc28384c30991cc4ebb02ec2e3ec99
ToppCellPBMC-Control-Myeloid-cDC-cDC|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

HLA-DMB DTNA SEMA4A SLC4A3

6.35e-051964944a9095ba3f6709f88f32bf09184553f4bd211f43
ToppCellPBMC-Severe-Myeloid-cDC|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

HLA-DMB DTNA SEMA4A SLC4A3

6.47e-0519749422e4ffb5de483eaf78f14badf3d08db898e3b3dd
ToppCellPBMC-Mild-Myeloid-cDC-cDC|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

HLA-DMB DTNA SEMA4A SLC4A3

6.47e-051974949162ede5572326c00ede0769fe7f4e0dd14d2340
ToppCellPBMC-Mild-Myeloid-cDC-cDC|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

HLA-DMB DTNA SEMA4A SLC4A3

6.47e-051974940460b6907743a354792b5bc40bff01aac7c41684
ToppCellPBMC-Severe-Myeloid-cDC|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

HLA-DMB DTNA SEMA4A SLC4A3

6.47e-05197494346974c6c5809a3fe88cbf067e2d64c340310a31
ToppCellCOVID-19_Mild-Myeloid-cDC|COVID-19_Mild / Disease group, lineage and cell class

HLA-DMB DTNA SEMA4A SLC4A3

6.47e-051974942901904b8a791fac2668fd737eff7e7144378db4
ToppCellHealthy_donor-cDC|Healthy_donor / disease group, cell group and cell class (v2)

HLA-DMB DTNA SEMA4A SLC4A3

6.47e-05197494b57a27e5b855bbdd1dfa352540599d260dc482aa
ToppCellPBMC-Severe-Myeloid-cDC-cDC|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

HLA-DMB DTNA SEMA4A SLC4A3

6.47e-051974941ae45c1ec3b3f88e0c1f99de58c58b1ec1b968ee
ToppCellPBMC-Mild-Myeloid-cDC|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

HLA-DMB DTNA SEMA4A SLC4A3

6.47e-05197494021c9c48375259b808e1f36a029c4fe6971c00eb
ToppCellHealthy/Control-cDC|World / Disease group and Cell class

HLA-DMB DTNA SEMA4A SLC4A3

6.47e-051974944497d4073f4d3e74de907325fba9eb4af5766bf4
ToppCellCOVID-19_Severe-Myeloid-cDC|COVID-19_Severe / Disease group, lineage and cell class

HLA-DMB DTNA SEMA4A SLC4A3

6.47e-05197494843b0f1cc26864ee635df7938c77552ee06fe00b
ToppCellPBMC-Mild-Myeloid-cDC|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

HLA-DMB DTNA SEMA4A SLC4A3

6.47e-0519749418df0e447bcea2a405a357563f87bacc57466227
ToppCellHealthy/Control-cDC|Healthy/Control / Disease group and Cell class

HLA-DMB DTNA SEMA4A SLC4A3

6.47e-05197494926423aae9fcf654f84b0f7621103a6a22d3aced
ToppCellmild_COVID-19-cDC|World / disease group, cell group and cell class (v2)

HLA-DMB DTNA SEMA4A SLC4A3

6.47e-0519749463e7b040c64f1e28b8db79980c7b580caa7d1b95
ToppCellHealthy_donor-cDC|World / disease group, cell group and cell class (v2)

HLA-DMB DTNA SEMA4A SLC4A3

6.47e-05197494a545fe3a80cd721bf01115bbb645753840ec9f40
ToppCellmild_COVID-19-cDC|mild_COVID-19 / disease group, cell group and cell class (v2)

HLA-DMB DTNA SEMA4A SLC4A3

6.47e-0519749444ebd3f967779bb7753fc6dcd9fde6d682f9ccd6
ToppCellPBMC-Severe-Myeloid-cDC-cDC|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

HLA-DMB DTNA SEMA4A SLC4A3

6.47e-05197494f78f44dcd7855c96f148678c1f416075aef71b4e
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Dendritic-conventional_dendritic_cell-DC_c2-CD1C|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

HLA-DMB DTNA SEMA4A SLC4A3

6.60e-05198494d0371e2ca9e25727b35985940f6228f9d8e49727
ToppCellNS-critical-LOC-Epithelial-Secretory_LYPD2|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

EXPH5 WWTR1 MESP1 CREB3L1

6.60e-051984944a481e1edb80b950c823ed926842cd5132cfb27f
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Dendritic-conventional_dendritic_cell|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

HLA-DMB DTNA SEMA4A SLC4A3

6.60e-0519849408ad0bece508bb4f9cc126d94839b5c89ce21ba8
ToppCellCOVID-19_Severe-cDC|World / disease group, cell group and cell class

HLA-DMB DTNA SEMA4A SLC4A3

6.60e-05198494c452334249f047265ae89dcabe7de446d968cae6
ToppCellMultiple_Sclerosis-Myeloid-cDC|Multiple_Sclerosis / Disease, Lineage and Cell Type

HLA-DMB DTNA SEMA4A SLC4A3

6.60e-05198494ac139bfbf52b2feddb0c05b0708c8c9efbe119c9
ToppCellBronchial-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DUOXA1 EXPH5 DAPK1 WWC1

6.73e-051994945f7da3eab58ace6cddb3179a415cd839d5767958
ToppCellBronchial-NucSeq-Epithelial-Epi_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DUOXA1 EXPH5 DAPK1 WWC1

6.73e-05199494725610310e5c5fd7120c0be9acb55bf152026ddd
ToppCellcontrol-cDC|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

HLA-DMB DTNA SEMA4A SLC4A3

6.73e-0519949431825ba336603fe940dea6022e18ec25af110f4c
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia/MHC|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

DTNA WWTR1 SPOCD1 SLC4A3

6.86e-05200494ac5843142e0f8a5bcd2c3a784ea13b2f955a32fd
ToppCellmild-cDC|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

HLA-DMB DTNA SEMA4A SLC4A3

6.86e-0520049486f585bf9066b179bbcbc703bf43f15da4a07284
ToppCellcontrol-cDC|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

HLA-DMB DTNA SEMA4A SLC4A3

6.86e-052004944a6d17a4225be38537d3dd8a39512051f597f4e0
ToppCellsevere-cDC|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

HLA-DMB DTNA SEMA4A SLC4A3

6.86e-0520049423e3d2fb86a71f62cca32640842fbba5dd163453
ToppCellParenchymal-10x5prime-Epithelial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

DUOXA1 EXPH5 CREB3L1 WWC1

6.86e-052004944e5b6cb014d9bcb58e13c7511c86c43e27c496e4
ToppCellsevere-cDC|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

HLA-DMB DTNA SEMA4A SLC4A3

6.86e-0520049426e04ea276dbca5cde48335c401269c7123b54d2
ToppCellTracheal-NucSeq-Epithelial-Epi_submucosal-gland|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DAPK1 XKR6 CREB3L1 WWC1

6.86e-052004940eb9ad8c0373bcc62029ec21c590ed03aaacd039
ToppCellmild-cDC|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

HLA-DMB DTNA SEMA4A SLC4A3

6.86e-05200494d6409ee5b9067be3dd2f852825e09151b5b22d7c
ToppCellBiopsy_Other_PF-Epithelial|Biopsy_Other_PF / Sample group, Lineage and Cell type

DUOXA1 EXPH5 CREB3L1 WWC1

6.86e-052004941ef4d5ae698fa721e0f510bf0d918bd8d3b00591
ToppCellBronchus_Control_(B.)-Endothelial-TX-Endothelial-2|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

SPTBN5 ACOT2 CREB3L4

9.76e-0581493a1193b2cfb84a6b6593779fef5f54a61567a12d7
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_ALM_Npw|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

EXPH5 ACOT1 XKR6

2.61e-04113493165de4316059222f33d1e51aeff4554037c0b937
ToppCell356C-Epithelial_cells-Epithelial-H_(AT1)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

MAP3K14 MESP1 SLC4A3

2.97e-041184933b077ad5c68c01b3fcc93f203cb130bb90705af9
ToppCell356C-Epithelial_cells-Epithelial-H_(AT1)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

MAP3K14 MESP1 SLC4A3

2.97e-0411849308bdf7bc3c9dcbc0f690658fe14e6cc4b9581698
ToppCelldroplet-Lung-1m-Hematologic-myeloid-intermediate_monocyte-intermediate_monocyte_l14|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PIM2 POFUT1 CENATAC

4.12e-0413249314a512f433315892bf0326419f23d0d5919d01ec
ToppCellPBMC-Mild-cDC_4|Mild / Compartment, Disease Groups and Clusters

EXPH5 DBF4B SLC4A3

4.21e-04133493e53fbd69775a4bff61de82557342f7ac80915c4d
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6_CT-L6_CT_VISp_Gpr139|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SPTBN5 SEMA4A CREB3L1

4.31e-04134493917b8951dd4c870b6b92f2e73e02dac884330c30
ToppCell3'_v3-blood-Lymphocytic_T_CD4-T_CD4/CD8|blood / Manually curated celltypes from each tissue

SIX5 ATG2A CENATAC

4.40e-04135493ae2d3a42e567b5bade304c0caa497eb725be3565
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling-Cycling_Connecting_Tubule_Cell_low-phase|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CORO2B ACOT1 CREB3L1

4.69e-04138493cd2f4682fcfd0275ce0640150bbb18da839e5c0a
ToppCellControl-Epithelial_alveolar-AT_1-Differentiating_AT2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PCNX4 DBF4B CENATAC

4.69e-04138493611fe0fb284e12678f9c47a0bdbfc367a93c52b3
ToppCell10x3'2.3-week_12-13-Myeloid_DC-DC-DC2|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

KCNH6 HLA-DMB DTNA

4.89e-04140493c3331cb7720f93af8bab35d02c6cbe87dd324d91
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L2/3_IT-L2/3_IT_ALM_Macc1_Lrg1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

IGFN1 EXPH5 XKR6

5.10e-04142493d08e1880425d285c4433014fe0242ac7ff7734af
ToppCellCOVID-19-Heart-CM_5_(RYR2-)|COVID-19 / Disease (COVID-19 only), tissue and cell type

IGFN1 KLHL40 PCNT

5.31e-04144493f92e03dd784e31a9e5dbd4f4c3a6517ea19210cf
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L2/3_IT|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SPTBN5 IGFN1 EXPH5

5.75e-04148493d5cace5605bff2bb8248fadb51f2dad7539930ba
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_B-B_cell|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

MAP3K14 KMT2A LINC00311

5.87e-0414949354c9c6282f5f5de43dfaf2972fab3e3dcf9838a3
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_B|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

MAP3K14 KMT2A LINC00311

5.87e-0414949314d2e8cab97108d8fa94e540c1957b73ed32dc73
DrugMemantine Hydrochloride [41100-52-1]; Down 200; 18.6uM; MCF7; HT_HG-U133A

PIM2 CDK13 EXPH5 POFUT1 ATG2A SEMA4A

3.65e-061944967354_DN
DrugChlorambucil [305-03-3]; Down 200; 13.2uM; MCF7; HT_HG-U133A

PIM2 CDK13 DTNA DBF4B POFUT1 SEMA4A

4.11e-061984963869_DN
DrugEtifenin [63245-28-3]; Down 200; 12.4uM; MCF7; HT_HG-U133A

CEP72 DTNA SIPA1L3 MAP3K14 POFUT1 SEMA4A

4.35e-062004962838_DN
DrugAC1L9NDR

HTR1A DUOXA1

1.36e-053492CID000449671
DrugAC1L8V5K

HTR1A UBR5 SEMA4A

4.04e-0531493CID000408611
DrugOxalamine citrate salt [1949-20-8]; Down 200; 9.2uM; MCF7; HT_HG-U133A

PIM2 DTNA SIPA1L3 PPP6R1 SEMA4A

5.57e-051914954969_DN
DrugAndrosterone [53-41-8]; Down 200; 13.8uM; MCF7; HT_HG-U133A

PIM2 DTNA SIPA1L3 POFUT1 SEMA4A

6.00e-051944955696_DN
DrugMoxisylyte hydrochoride [964-52-3]; Up 200; 12.6uM; PC3; HT_HG-U133A

PIM2 DTNA SIPA1L3 MAP3K14 WWC1

6.15e-051954957255_UP
Drug17-AAG; Up 200; 1uM; MCF7; HT_HG-U133A

EXPH5 MAP3K14 KMT2A WWTR1 POFUT1

6.15e-051954951650_UP
DrugProgesterone [57-83-0]; Down 200; 12.8uM; MCF7; HT_HG-U133A

PIM2 DTNA SIPA1L3 WWTR1 POFUT1

6.15e-051954953287_DN
DrugNaringenine [480-41-1]; Up 200; 14.6uM; MCF7; HT_HG-U133A

PIM2 DBF4B POFUT1 ATG2A WWC1

6.15e-051954953278_UP
DrugDipivefrin hydrochloride [64019-93-8]; Down 200; 10.4uM; MCF7; HT_HG-U133A

CDK13 DTNA EXPH5 SIPA1L3 WWTR1

6.30e-051964956766_DN
DrugSulfameter [651-06-9]; Down 200; 14.2uM; MCF7; HT_HG-U133A

SIPA1L3 KMT2A NR1H3 TSR3 GGCX

6.45e-051974956212_DN
DrugAtropine sulfate monohydrate [5908-99-6]; Up 200; 5.8uM; PC3; HT_HG-U133A

KCNH6 DTNA DBF4B SEMA4A SLC4A3

6.61e-051984955865_UP
Drug1,4-butanedithiol

HLA-DMB DTNA

6.77e-056492CID000079148
DrugFlecainide acetate [54143-56-5]; Up 200; 8.4uM; MCF7; HT_HG-U133A

PIM2 CDK13 DTNA EXPH5 SCYL3

6.93e-052004953418_UP
Diseaseshort QT syndrome (implicated_via_orthology)

KCNH6 SLC4A3

7.77e-063482DOID:0050793 (implicated_via_orthology)
DiseaseNonorganic psychosis

KCNH6 WWC1 PCNT

1.96e-0469483C0349204
DiseasePsychotic Disorders

KCNH6 WWC1 PCNT

6.02e-04101483C0033975
Diseasemental development measurement

DTNA WWTR1

7.59e-0425482EFO_0008230
DiseaseAcute Myeloid Leukemia, M1

PIM2 KMT2A DAPK1

1.12e-03125483C0026998
DiseaseAcute Myeloid Leukemia (AML-M2)

PIM2 KMT2A DAPK1

1.12e-03125483C1879321
DiseaseCarcinoma, Transitional Cell

KMT2A DAPK1

2.04e-0341482C0007138
DiseaseLeukemia, Myelocytic, Acute

PIM2 KMT2A DAPK1

2.82e-03173483C0023467
Diseaselymphocyte percentage of leukocytes

UBR5 CDK13 NR1H3 NSL1 XKR6

4.41e-03665485EFO_0007993

Protein segments in the cluster

PeptideGeneStartEntry
NPLDGPTWEVLAMPL

LINC00311

11

Q8N616
PTWEVLAMPLPLGPA

LINC00311

16

Q8N616
EPMGLLWALEPEKPL

ACOT1

76

Q86TX2
LLDPPDPLGKDWCLL

DAPK1

1316

P53355
PTMADDLGEPAPLWP

SLC4A3

466

P48751
TLLPMEPPDGWEINP

CREB3L1

441

Q96BA8
WPSPEEPLRELMENL

GVINP1

141

Q7Z2Y8
GLEPMGLLWALEPEK

ACOT2

136

P49753
EKMPWSQLCGELPPL

CEP72

266

Q9P209
WSLDENGLPLIPMPQ

CC2D2B

626

Q6DHV5
MPPPDLPLWQDCHEL

CDK13

1006

Q14004
LLMWEPADLLPTPDP

ATG2A

841

Q2TAZ0
MSLWLGAPVPDIPPD

NR1H3

1

Q13133
MAGSPELVVLDPPWD

NSL1

1

Q96IY1
MPRPELPLPEGWEEA

WWC1

1

Q8IX03
ASGLWPELLQEMPPR

KCNH6

791

Q9H252
LPPPDALLLWAMEQV

PCNX4

261

Q63HM2
EESGMPPPWDASLLE

EXPH5

191

Q8NEV8
DHLDSEWLGMPPLPS

KLHL40

386

Q2TBA0
WDSLIPDEMPDSPIQ

PCNT

2166

O95613
PIPALLSLTEESMPW

SCYL3

601

Q8IZE3
PSRELGPQDLLWMLD

FCSK

496

Q8N0W3
EPILRDWTPGLSPMQ

HLA-DMB

201

P28068
MTPGTEPALTPDEWL

CORO2B

371

Q9UQ03
ALLPGEWSPAEDMPL

DBF4B

461

Q8NFT6
LISIPPMLGWRTPED

HTR1A

166

P08908
DTLMSDPPPQCLVWL

DTNA

211

Q9Y4J8
FPDDMPTLSALPWEE

KMT2A

1086

Q03164
DLPPAPELDWMETGP

CENATAC

206

Q86UT8
PMPEVTWLKDGLPLP

IGFN1

976

Q86VF2
PMLEWSPEEGGLLSP

DUOXA1

291

Q1HG43
MDLGIPDLLDAWLEP

CREB3L4

1

Q8TEY5
ESGMWEPLPLSSLEP

MAP3K14

736

Q99558
LLLLPLPGMPAGSWD

POFUT1

16

Q9H488
MLEVTWSSLPPDPPE

TBC1D25

426

Q3MII6
MGDLFSLFWEVDPPP

SSMEM1

1

Q8WWF3
LLDPWMQTPAEDVPL

PIM2

281

Q9P1W9
MALPALGLDPWSLLG

SEMA4A

1

Q9H3S1
PGLMPLPDTAAGLEW

SIPA1L3

1636

O60292
PPEGLMLSPAAVPVW

SIX5

651

Q8N196
PLLPGDVLALLETWM

MESP1

241

Q9BRJ9
SEGLWDPLAPMEPLL

SPTBN5

2601

Q9NRC6
GMDVSPSEPPWELLP

ATF6B

66

Q99941
LLWGIPLPPDVEPMA

XKR6

516

Q5GH73
FPLLDALRPLPLDWM

GGCX

101

P38435
LPCLPPWEGVLDMFS

SPOCD1

861

Q6ZMY3
LLEPPKLEPLQMTWG

PPP6R1

331

Q9UPN7
CMGGIRDPDWLDLPP

UBR5

826

O95071
PGPAALPCTLAMWEL

TSR3

51

Q9UJK0
TDELPLPPGWEMTFT

WWTR1

121

Q9GZV5