Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	Sema	SEMA6C PLXNA4 PLXNA1 SEMA4G	1.14e-05	31	85	4	SM00630
Domain	Semap_dom	SEMA6C PLXNA4 PLXNA1 SEMA4G	1.14e-05	31	85	4	IPR001627
Domain	Sema	SEMA6C PLXNA4 PLXNA1 SEMA4G	1.14e-05	31	85	4	PF01403
Domain	SEMA	SEMA6C PLXNA4 PLXNA1 SEMA4G	1.14e-05	31	85	4	PS51004
Domain	PSI	SEMA6C PLXNA4 PLXNA1 SEMA4G	1.30e-05	32	85	4	PF01437
Domain	Plexin_repeat	SEMA6C PLXNA4 PLXNA1 SEMA4G	1.30e-05	32	85	4	IPR002165
Domain	-	CLEC18A CLEC18B CLEC18C	3.98e-05	15	85	3	3.40.33.10
Domain	CAP	CLEC18A CLEC18B CLEC18C	3.98e-05	15	85	3	PF00188
Domain	CAP_domain	CLEC18A CLEC18B CLEC18C	3.98e-05	15	85	3	IPR014044
Domain	SCP	CLEC18A CLEC18B CLEC18C	3.98e-05	15	85	3	SM00198
Domain	Allrgn_V5/Tpx1	CLEC18A CLEC18B CLEC18C	3.98e-05	15	85	3	IPR001283
Domain	PSI	SEMA6C PLXNA4 PLXNA1 SEMA4G	4.72e-05	44	85	4	IPR016201
Domain	PSI	SEMA6C PLXNA4 PLXNA1 SEMA4G	5.64e-05	46	85	4	SM00423
Domain	C_TYPE_LECTIN_1	CLEC18A CLEC18B CLEC18C PKD1L2	4.86e-04	80	85	4	PS00615
Domain	Znf_FYVE_PHD	SYTL3 KDM4C ZBTB4 RNF34 EEA1	5.58e-04	147	85	5	IPR011011
Domain	Lectin_C	CLEC18A CLEC18B CLEC18C PKD1L2	5.84e-04	84	85	4	PF00059
Domain	CLECT	CLEC18A CLEC18B CLEC18C PKD1L2	5.84e-04	84	85	4	SM00034
Domain	C_TYPE_LECTIN_2	CLEC18A CLEC18B CLEC18C PKD1L2	6.11e-04	85	85	4	PS50041
Domain	C-type_lectin-like	CLEC18A CLEC18B CLEC18C PKD1L2	6.39e-04	86	85	4	IPR001304
Domain	EGF_3	CLEC18A FBLN7 CLEC18B MEGF6 CLEC18C F12	7.11e-04	235	85	6	PS50026
Domain	EGF	CLEC18A FBLN7 CLEC18B MEGF6 CLEC18C F12	7.11e-04	235	85	6	SM00181
Domain	Plexin_cytopl	PLXNA4 PLXNA1	7.22e-04	9	85	2	PF08337
Domain	Plexin_cytoplasmic_RasGAP_dom	PLXNA4 PLXNA1	7.22e-04	9	85	2	IPR013548
Domain	Plexin	PLXNA4 PLXNA1	7.22e-04	9	85	2	IPR031148
Domain	EGF-like_dom	CLEC18A FBLN7 CLEC18B MEGF6 CLEC18C F12	9.60e-04	249	85	6	IPR000742
Domain	C-type_lectin_CS	CLEC18A CLEC18B CLEC18C	9.84e-04	43	85	3	IPR018378
Domain	-	CLEC18A CLEC18B CLEC18C PKD1L2	1.00e-03	97	85	4	3.10.100.10
Domain	C-type_lectin-like/link	CLEC18A CLEC18B CLEC18C PKD1L2	1.08e-03	99	85	4	IPR016186
Domain	EGF_1	CLEC18A FBLN7 CLEC18B MEGF6 CLEC18C F12	1.09e-03	255	85	6	PS00022
Domain	EGF-like_CS	CLEC18A FBLN7 CLEC18B MEGF6 CLEC18C F12	1.22e-03	261	85	6	IPR013032
Domain	DUF4599	SPATA31D4 SPATA31D3	1.31e-03	12	85	2	PF15371
Domain	DUF4599	SPATA31D4 SPATA31D3	1.31e-03	12	85	2	IPR027970
Domain	EGF_2	CLEC18A FBLN7 CLEC18B MEGF6 CLEC18C F12	1.32e-03	265	85	6	PS01186
Domain	CTDL_fold	CLEC18A CLEC18B CLEC18C PKD1L2	1.44e-03	107	85	4	IPR016187
Domain	Wnt	WNT1 WNT10A	3.33e-03	19	85	2	IPR005817
Domain	Wnt_CS	WNT1 WNT10A	3.33e-03	19	85	2	IPR018161
Domain	wnt	WNT1 WNT10A	3.33e-03	19	85	2	PF00110
Domain	WNT1	WNT1 WNT10A	3.33e-03	19	85	2	SM00097
Domain	WNT1	WNT1 WNT10A	3.33e-03	19	85	2	PS00246
Domain	Semaphorin	SEMA6C SEMA4G	3.69e-03	20	85	2	IPR027231
Pubmed	Human CLEC18 Gene Cluster Contains C-type Lectins with Differential Glycan-binding Specificity.	CLEC18A CLEC18B CLEC18C	1.51e-08	3	87	3	26170455
Pubmed	The C-type lectin-like domain superfamily.	CLEC18A CLEC18B CLEC18C	1.51e-08	3	87	3	16336259
Pubmed	Endosomal TLR3 co-receptor CLEC18A enhances host immune response to viral infection.	CLEC18A CLEC18B CLEC18C	1.51e-08	3	87	3	33603190
Pubmed	The mannose receptor mediates uptake of soluble but not of cell-associated antigen for cross-presentation.	CLEC18A CLEC18B CLEC18C	6.04e-08	4	87	3	16709836
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	VWA5B2 SEMA6C RHBDF1 MEGF6 KIF26A XPO6 SGSM2 MCM3AP KSR2 ZBTB4 MCM5 PLA2G6 DEPDC5 ZFPM1 PLXNA1	9.58e-08	1105	87	15	35748872
Pubmed	Control of species-dependent cortico-motoneuronal connections underlying manual dexterity.	SEMA6C PLXNA4 PLXNA1	1.26e-06	9	87	3	28751609
Pubmed	Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.	VWA5B2 SPATA31D4 SPATA31D3 KIF26A YTHDC2 SYBU ZFPM1	2.05e-06	233	87	7	37704626
Pubmed	On and off retinal circuit assembly by divergent molecular mechanisms.	SEMA6C PLXNA4 PLXNA1	3.27e-06	12	87	3	24179230
Pubmed	A midline switch of receptor processing regulates commissural axon guidance in vertebrates.	WNT1 PLXNA4 PLXNA1	5.39e-06	14	87	3	20159958
Pubmed	TrkB-dependent EphrinA reverse signaling regulates callosal axon fasciculate growth downstream of Neurod2/6.	SEMA6C PLXNA4 PLXNA1 SEMA4G	6.00e-06	47	87	4	35462405
Pubmed	The lurcher gene induces apoptotic death in cerebellar Purkinje cells.	CLU GRID2	6.19e-06	2	87	2	7743930
Pubmed	Analysis of protein variations in adult and postnatal day 11 staggerer and lurcher mutant mice.	RORA GRID2	6.19e-06	2	87	2	8513552
Pubmed	Discrimination learning in Rora(sg) and Grid2(ho) mutant mice.	RORA GRID2	6.19e-06	2	87	2	18583162
Pubmed	Abnormal IL-1beta cytokine expression in the cerebellum of the ataxic mutant mice staggerer and lurcher.	RORA GRID2	6.19e-06	2	87	2	9813341
Pubmed	Rotorod sensorimotor learning in cerebellar mutant mice.	RORA GRID2	6.19e-06	2	87	2	7478307
Pubmed	Identification of plexin A4 as a novel clusterin receptor links two Alzheimer's disease risk genes.	CLU PLXNA4	6.19e-06	2	87	2	27378688
Pubmed	Stunted morphologies of cerebellar Purkinje cells in lurcher and staggerer mice are cell-intrinsic effects of the mutant genes.	RORA GRID2	6.19e-06	2	87	2	7673468
Pubmed	Spatial and temporal changes in natural and target deprivation-induced cell death in the mouse inferior olive.	WNT1 GRID2	6.19e-06	2	87	2	10756063
Pubmed	Differential IL-6 mRNA expression by stimulated peripheral macrophages of Staggerer and Lurcher cerebellar mutant mice.	RORA GRID2	6.19e-06	2	87	2	1804324
Pubmed	Purkinje cell dendrites in staggerer<-->wild type mouse chimeras lack the aberrant morphologies found in lurcher<-->wild type chimeras.	RORA GRID2	6.19e-06	2	87	2	8509510
Pubmed	Optic chiasm presentation of Semaphorin6D in the context of Plexin-A1 and Nr-CAM promotes retinal axon midline crossing.	SEMA6C PLXNA4 PLXNA1	8.27e-06	16	87	3	22632726
Pubmed	An extracellular biochemical screen reveals that FLRTs and Unc5s mediate neuronal subtype recognition in the retina.	SEMA6C PLXNA4 PLXNA1 SEMA4G	9.02e-06	52	87	4	26633812
Pubmed	Structural Basis for Plexin Activation and Regulation.	PLXNA4 PLXNA1	1.85e-05	3	87	2	27397516
Pubmed	Spatial learning in a Z-maze by cerebellar mutant mice.	RORA GRID2	1.85e-05	3	87	2	8848495
Pubmed	Repulsive and attractive semaphorins cooperate to direct the navigation of cardiac neural crest cells.	PLXNA4 PLXNA1	1.85e-05	3	87	2	18625214
Pubmed	The Tec kinase ITK is essential for ILC2 survival and epithelial integrity in the intestine.	RORA ITK	1.85e-05	3	87	2	30770814
Pubmed	Sensorimotor learning in three cerebellar mutant mice.	RORA GRID2	1.85e-05	3	87	2	8833100
Pubmed	Staggerer mutant mouse Purkinje cells do not contain detectable calmodulin mRNA.	RORA GRID2	1.85e-05	3	87	2	2355223
Pubmed	A semaphorin code defines subpopulations of spinal motor neurons during mouse development.	SEMA6C PLXNA4 PLXNA1	2.95e-05	24	87	3	15869472
Pubmed	Multiple developmental programs are altered by loss of Zic1 and Zic4 to cause Dandy-Walker malformation cerebellar pathogenesis.	LHX2 WNT1 RORA	3.34e-05	25	87	3	21307096
Pubmed	Chromosome assignment of four plexin A genes (Plxna1, Plxna2, Plxna3, Plxna4) in mouse, rat, Syrian hamster and Chinese hamster.	PLXNA4 PLXNA1	3.70e-05	4	87	2	11306810
Pubmed	PlexinA polymorphisms mediate the developmental trajectory of human corpus callosum microstructure.	PLXNA4 PLXNA1	3.70e-05	4	87	2	25518740
Pubmed	Dependence of parvalbumin expression on Purkinje cell input in the deep cerebellar nuclei.	RORA GRID2	3.70e-05	4	87	2	9514513
Pubmed	WNT10A and WNT6, clustered in human chromosome 2q35 region with head-to-tail manner, are strongly coexpressed in SW480 cells.	WNT1 WNT10A	3.70e-05	4	87	2	11350055
Pubmed	The Purkinje cell class may extend beyond the cerebellum.	RORA GRID2	3.70e-05	4	87	2	2077109
Pubmed	Semaphorins guide the entry of dendritic cells into the lymphatics by activating myosin II.	SEMA6C PLXNA1	6.16e-05	5	87	2	20512151
Pubmed	Evolutionary conservation of sequence and expression of the bHLH protein Atonal suggests a conserved role in neurogenesis.	LHX2 WNT1	6.16e-05	5	87	2	8872459
Pubmed	Spatial rearrangement of Purkinje cell subsets forms the transverse and longitudinal compartmentalization in the mouse embryonic cerebellum.	SKOR2 RORA	6.16e-05	5	87	2	28542916
Pubmed	The ciliogenic transcription factor Rfx3 is required for the formation of the thalamocortical tract by regulating the patterning of prethalamus and ventral telencephalon.	LHX2 PLXNA4 LHX6	8.55e-05	34	87	3	25631876
Pubmed	Expression of the metabotropic glutamate receptor mGluR1 alpha and the ionotropic glutamate receptor GluR1 in the brain during the postnatal development of normal mouse and in the cerebellum from mutant mice.	RORA GRID2	9.22e-05	6	87	2	8230318
Pubmed	Ectopic myelinating oligodendrocytes in the dorsal spinal cord as a consequence of altered semaphorin 6D signaling inhibit synapse formation.	SEMA6C PLXNA1	9.22e-05	6	87	2	21831918
Pubmed	WNT5A is transported via lipoprotein particles in the cerebrospinal fluid to regulate hindbrain morphogenesis.	CLU WNT1 WNT10A	9.34e-05	35	87	3	30940800
Pubmed	Sema6D acts downstream of bone morphogenetic protein signalling to promote atrioventricular cushion development in mice.	SEMA6C PLXNA4 PLXNA1	9.34e-05	35	87	3	28172500
Pubmed	Comparison of the gene expression profiles from normal and Fgfrl1 deficient mouse kidneys reveals downstream targets of Fgfrl1 signaling.	CLEC18A CLEC18B CLEC18C	1.10e-04	37	87	3	22432025
Pubmed	Semaphorin-6A controls guidance of corticospinal tract axons at multiple choice points.	PLXNA4 PLXNA1	1.29e-04	7	87	2	19063725
Pubmed	Increased proximal bifurcation of CA1 pyramidal apical dendrites in sema3A mutant mice.	PLXNA4 PLXNA1	1.29e-04	7	87	2	19655386
Pubmed	Single-Cell Multiomic Approaches Reveal Diverse Labeling of the Nervous System by Common Cre-Drivers.	WNT1 WNT10A	1.29e-04	7	87	2	33935652
Pubmed	The expression of plexins during mouse embryogenesis.	PLXNA4 PLXNA1	1.72e-04	8	87	2	15661641
Pubmed	Behavioral effects of neonatal lesions on the cerebellar system.	RORA GRID2	1.72e-04	8	87	2	25907855
Pubmed	Analysis of epithelial-mesenchymal interactions in the initial morphogenesis of the mammalian tooth.	WNT1 WNT10A	1.72e-04	8	87	2	9769173
Pubmed	Comparative Transcriptomic and Epigenomic Analyses Reveal New Regulators of Murine Brown Adipogenesis.	PIM1 RREB1	1.72e-04	8	87	2	27923061
Pubmed	Integration of opposing semaphorin guidance cues in cortical axons.	PLXNA4 PLXNA1	1.72e-04	8	87	2	22368082
Pubmed	Postmitotic Nkx2-1 controls the migration of telencephalic interneurons by direct repression of guidance receptors.	PLXNA4 LHX6	1.72e-04	8	87	2	18786357
Pubmed	Interleukin-1 hyperproduction by in vitro activated peripheral macrophages from cerebellar mutant mice.	RORA GRID2	1.72e-04	8	87	2	2230805
Pubmed	PlexinA1 signaling directs the segregation of proprioceptive sensory axons in the developing spinal cord.	SEMA6C PLXNA4 PLXNA1 SEMA4G	2.18e-04	117	87	4	17145500
Pubmed	PlexinA4-Semaphorin3A-mediated crosstalk between main cortical interneuron classes is required for superficial interneuron lamination.	PLXNA4 LHX6	2.20e-04	9	87	2	33503438
Pubmed	Genome-wide interrogation of germline genetic variation associated with treatment response in childhood acute lymphoblastic leukemia.	DGKB MAML2	2.20e-04	9	87	2	19176441
Pubmed	Spontaneous and induced mouse mutations with cerebellar dysfunctions: behavior and neurochemistry.	RORA GRID2	2.20e-04	9	87	2	16499884
Pubmed	The role of neuropilins in cell signalling.	PLXNA4 PLXNA1	2.20e-04	9	87	2	19909241
Pubmed	Plexin A3 and plexin A4 convey semaphorin signals during facial nerve development.	PLXNA4 PLXNA1	2.75e-04	10	87	2	18804103
Pubmed	Peripheral macrophage abnormalities in mutant mice with spinocerebellar degeneration.	RORA GRID2	2.75e-04	10	87	2	1565842
Pubmed	The isthmic neuroepithelium is essential for cerebellar midline fusion.	WNT1 RORA	2.75e-04	10	87	2	14507778
Pubmed	Roof plate and dorsal spinal cord dl1 interneuron development in the dreher mutant mouse.	LHX2 WNT1	2.75e-04	10	87	2	15183721
Pubmed	Oncogenic Mutations Rewire Signaling Pathways by Switching Protein Recruitment to Phosphotyrosine Sites.	PDGFRB ITK	3.35e-04	11	87	2	31585087
Pubmed	Neuronal patterning by BMPs: a requirement for GDF7 in the generation of a discrete class of commissural interneurons in the mouse spinal cord.	LHX2 WNT1	4.02e-04	12	87	2	9808626
Pubmed	Functional loss of semaphorin 3C and/or semaphorin 3D and their epistatic interaction with ret are critical to Hirschsprung disease liability.	PLXNA4 PLXNA1	4.02e-04	12	87	2	25839327
Pubmed	PLXNA1 and PLXNA3 cooperate to pattern the nasal axons that guide gonadotropin-releasing hormone neurons.	PLXNA4 PLXNA1	4.02e-04	12	87	2	31690636
Pubmed	Deletion of Sema3a or plexinA1/plexinA3 causes defects in sensory afferent projections of statoacoustic ganglion neurons.	PLXNA4 PLXNA1	4.02e-04	12	87	2	23991118
Pubmed	Molecular dynamics of Dkk4 modulates Wnt action and regulates meibomian gland development.	WNT1 WNT10A	4.02e-04	12	87	2	27864382
Pubmed	Transcriptome profiling reveals expression signatures of cranial neural crest cells arising from different axial levels.	PLXNA4 PLXNA1	4.02e-04	12	87	2	28407732
Pubmed	Transmembrane semaphorin signalling controls laminar stratification in the mammalian retina.	PLXNA4 PLXNA1	4.02e-04	12	87	2	21270798
Pubmed	Functional assembly of accessory optic system circuitry critical for compensatory eye movements.	PLXNA4 PLXNA1	4.74e-04	13	87	2	25959730
Pubmed	CbGRiTS: cerebellar gene regulation in time and space.	RORA PCSK9	4.74e-04	13	87	2	25446528
Pubmed	Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored semaphorins in vertebrates.	PLXNA4 PLXNA1	4.74e-04	13	87	2	10520995
Pubmed	Plexin signaling via off-track and rho family GTPases.	PLXNA4 PLXNA1	4.74e-04	13	87	2	11604131
Pubmed	Wnt signaling plays an essential role in neuronal specification of the dorsal spinal cord.	LHX2 WNT1	4.74e-04	13	87	2	11877374
Pubmed	Identification of a novel transcriptional corepressor, Corl2, as a cerebellar Purkinje cell-selective marker.	SKOR2 RORA	4.74e-04	13	87	2	18522874
Pubmed	Opposing roles of hepatic stellate cell subpopulations in hepatocarcinogenesis.	LHX2 PDGFRB	4.74e-04	13	87	2	36198802
Pubmed	Semaphorin3A, Neuropilin-1, and PlexinA1 are required for lymphatic valve formation.	PLXNA4 PLXNA1	4.74e-04	13	87	2	22723296
Pubmed	LIM genes parcellate the embryonic amygdala and regulate its development.	LHX2 LHX6	4.74e-04	13	87	2	15295034
Pubmed	β3GnT2 maintains adenylyl cyclase-3 signaling and axon guidance molecule expression in the olfactory epithelium.	PLXNA4 PLXNA1	5.52e-04	14	87	2	21525298
Pubmed	AUTS2 Governs Cerebellar Development, Purkinje Cell Maturation, Motor Function and Social Communication.	RORA GRID2	5.52e-04	14	87	2	33305180
Pubmed	Altered proliferative ability of neuronal progenitors in PlexinA1 mutant mice.	LHX6 PLXNA1	5.52e-04	14	87	2	25975775
Pubmed	Expression patterns of Wnt genes in mouse gut development.	WNT1 WNT10A	6.36e-04	15	87	2	11429295
Pubmed	Expression and estradiol regulation of Wnt genes in the mouse blastocyst identify a candidate pathway for embryo-maternal signaling at implantation.	WNT1 WNT10A	6.36e-04	15	87	2	15044261
Pubmed	Vascular-Derived Vegfa Promotes Cortical Interneuron Migration and Proximity to the Vasculature in the Developing Forebrain.	PDGFRB LHX6	6.36e-04	15	87	2	29901792
Pubmed	Genome-wide association study of advanced age-related macular degeneration identifies a role of the hepatic lipase gene (LIPC).	HTRA1 RREB1	6.36e-04	15	87	2	20385826
Pubmed	Integrated microarray and ChIP analysis identifies multiple Foxa2 dependent target genes in the notochord.	HTRA1 CLCN2 CLU ZBTB4	6.49e-04	156	87	4	22008794
Pubmed	Molecular genetic studies of Wnt signaling in the mouse.	WNT1 WNT10A	7.26e-04	16	87	2	10585256
Pubmed	Allocation of paraventricular and supraoptic neurons requires Sim1 function: a role for a Sim1 downstream gene PlexinC1.	PLXNA4 PLXNA1	7.26e-04	16	87	2	17356169
Pubmed	The Wnts.	WNT1 WNT10A	7.26e-04	16	87	2	9889131
Pubmed	Delineation of multiple subpallial progenitor domains by the combinatorial expression of transcriptional codes.	LHX2 LHX6	7.26e-04	16	87	2	17804629
Pubmed	Genetic ablation reveals that the roof plate is essential for dorsal interneuron specification.	LHX2 WNT1	7.26e-04	16	87	2	10693795
Pubmed	Forced expression of platelet-derived growth factor B in the mouse cerebellar primordium changes cell migration during midline fusion and causes cerebellar ectopia.	PDGFRB WNT1	7.26e-04	16	87	2	15207855
Pubmed	Expression of the semaphorins Sema 3D and Sema 3F in the developing parathyroid and thymus.	PLXNA4 PLXNA1	7.26e-04	16	87	2	18489001
Pubmed	Expression of LIM-homeodomain transcription factors in the developing and mature mouse retina.	LHX2 LHX6	7.26e-04	16	87	2	24333658
Pubmed	Balance between BDNF and Semaphorins gates the innervation of the mammary gland.	PLXNA4 SEMA4G	7.26e-04	16	87	2	30628891
Pubmed	Genome-wide association of body fat distribution in African ancestry populations suggests new loci.	LHX2 RREB1	7.26e-04	16	87	2	23966867
Pubmed	Socs1 binds to multiple signalling proteins and suppresses steel factor-dependent proliferation.	PDGFRB ITK	7.26e-04	16	87	2	10022833
Pubmed	The roof plate regulates cerebellar cell-type specification and proliferation.	LHX2 WNT1	7.26e-04	16	87	2	16790481
GeneFamily	Plexins	PLXNA4 PLXNA1	4.10e-04	9	62	2	683
GeneFamily	C-type lectin domain family	CLEC18A CLEC18B CLEC18C	5.59e-04	47	62	3	494
GeneFamily	LIM class homeoboxes	LHX2 LHX6	7.47e-04	12	62	2	522
GeneFamily	Wnt family\|Endogenous ligands	WNT1 WNT10A	1.91e-03	19	62	2	360
GeneFamily	Immunoglobulin like domain containing\|Semaphorins	SEMA6C SEMA4G	2.11e-03	20	62	2	736
Coexpression	NABA_ECM_AFFILIATED	SEMA6C CLEC18A CLEC18B PLXNA4 CLEC18C MUC2 PLXNA1 SEMA4G	4.74e-08	158	85	8	MM17063
Coexpression	NABA_ECM_AFFILIATED	SEMA6C CLEC18A CLEC18B PLXNA4 CLEC18C MUC2 PLXNA1 SEMA4G	8.35e-08	170	85	8	M5880
Coexpression	NABA_MATRISOME_ASSOCIATED	SEMA6C CLEC18A HTRA1 CLEC18B MEGF6 WNT1 PLXNA4 WNT10A CLEC18C MUC2 F12 PLXNA1 SEMA4G	7.20e-07	738	85	13	MM17058
Coexpression	NABA_MATRISOME	VWA5B2 SEMA6C CLEC18A FBLN7 HTRA1 CLEC18B MEGF6 WNT1 PLXNA4 WNT10A CLEC18C MUC2 F12 PLXNA1 SEMA4G	7.77e-07	1008	85	15	MM17056
Coexpression	NABA_MATRISOME_ASSOCIATED	SEMA6C CLEC18A HTRA1 CLEC18B MEGF6 WNT1 PLXNA4 WNT10A CLEC18C MUC2 F12 PLXNA1 SEMA4G	8.75e-07	751	85	13	M5885
Coexpression	NABA_MATRISOME	VWA5B2 SEMA6C CLEC18A FBLN7 HTRA1 CLEC18B MEGF6 WNT1 PLXNA4 WNT10A CLEC18C MUC2 F12 PLXNA1 SEMA4G	9.70e-07	1026	85	15	M5889
CoexpressionAtlas	Ectoderm Differentiated Cells_vs_Pluripotent Stem Cells-Confounder_removed-fold2.0_adjp0.05	SEMA6C CLEC18A FBLN7 EXD3 CLCN2 RHBDF1 CLEC18B MEGF6 CLU PDGFRB WNT1 CPT1C SGSM2 ZBTB4 CLEC18C PLA2G6 EDA2R PLXNA1	1.36e-05	1466	84	18	PCBC_ratio_ECTO_vs_SC_cfr-2X-p05
ToppCell	facs-Lung-18m-Hematologic-Lymphocytic_NK_ILC-Alox5+_lymphocyte-Alox5+_lymphocyte\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TRAF1 TAFA3 RORA GRID2 LAX1 ITK	1.32e-06	177	87	6	b7cfa3776f58377e35830780650d236b5cceecee
ToppCell	facs-Lung-18m-Hematologic-Lymphocytic_NK_ILC-Alox5+_lymphocyte\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TRAF1 TAFA3 RORA GRID2 LAX1 ITK	1.32e-06	177	87	6	1730e640986e50943bd781b7d949bcc5b7c12dde
ToppCell	facs-Lung-EPCAM-18m-Lymphocytic-Alox5+_Lymphocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRAF1 TAFA3 RORA GRID2 LAX1 ITK	1.46e-06	180	87	6	b28363626f4d2a552abde3434cc1df2e2121aba5
ToppCell	facs-Lung-EPCAM-18m-Lymphocytic-lymphocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRAF1 TAFA3 RORA GRID2 LAX1 ITK	1.46e-06	180	87	6	67b062f2ef7e20f392e00c646f4985c415d40de9
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m-Lymphocytic-T_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRAF1 SYTL3 MCM5 LHX6 ZNF367 ITK	1.50e-06	181	87	6	8a8061725e718c89a4c751a415120c5312acc757
ToppCell	Fetal_29-31_weeks-Mesenchymal-chondrocyte-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CLEC18A FBLN7 CLEC18B CLU PDGFRB CLEC18C	1.71e-06	185	87	6	8ed10ba581849c9c4ac4397226be2b62b4b3b900
ToppCell	Fetal_29-31_weeks-Mesenchymal-chondrocyte\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CLEC18A FBLN7 CLEC18B CLU PDGFRB CLEC18C	1.71e-06	185	87	6	b8052cebb73f41abe6faf0aa847be7c8ef23ae94
ToppCell	Bronchial-10x5prime-Immune_Lymphocytic-T-T_CD8-MAIT\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	TRAF1 SYTL3 WNT1 RORA LAX1 ITK	2.18e-06	193	87	6	9aeb34d7a24f84abff38d7b8cf0ec707c08eb27f
ToppCell	10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-Reg_T\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FBLN7 TRAF1 WNT10A RORA LAX1 ITK	2.38e-06	196	87	6	157e98bd079e0217c3380e245775794c5ba5c8bd
ToppCell	mLN-T_cell\|mLN / Region, Cell class and subclass	FBLN7 TRAF1 SYTL3 PIM1 RORA ITK	2.60e-06	199	87	6	caa37ec509b54e842564d754f100ab1b2a77a7c1
ToppCell	mLN-(1)_T_cell\|mLN / shred on region, Cell_type, and subtype	FBLN7 TRAF1 SYTL3 PIM1 RORA ITK	2.60e-06	199	87	6	4bf2641409c543c2167bff71efa95b00dd7bfe19
ToppCell	Hippocampus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Nxph3-Excitatory_Neuron.Slc17a7.Nxph3-Cplx3-Hs6st2_(Entorhinal_cortex)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	NLRP10 MUC2 F12 PCSK9	9.66e-06	68	87	4	75e81b353ef313d5e98d5c98d584335f1d1fa658
ToppCell	Hippocampus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Nxph3-Excitatory_Neuron.Slc17a7.Nxph3-Cplx3-Hs6st2_(Entorhinal_cortex)-\|Hippocampus / BrainAtlas - Mouse McCarroll V32	NLRP10 MUC2 F12 PCSK9	9.66e-06	68	87	4	01ba0ccc5732189a5c0c32cb7819289102711b93
ToppCell	10x5'-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8\|bone_marrow / Manually curated celltypes from each tissue	TRAF1 SYTL3 RORA MAML2 ITK	1.38e-05	156	87	5	1545169694f686d28648a68b552c2ae606599d66
ToppCell	PND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TRAF1 TAFA3 RORA LAX1 ITK	1.71e-05	163	87	5	476e94e1d132eaaecb9e376bd32748a75ad22081
ToppCell	T_cells-TFH-like_cells\|World / Immune cells in Kidney/Urine in Lupus Nephritis	FBLN7 TRAF1 KSR2 WNT10A BBS12	1.76e-05	164	87	5	b10cf59f4cc37ca6cd0ecf71d7de278cc2bdd8b5
ToppCell	390C-Lymphocytic-NK_cells-NK_cell_B0\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	FBLN7 EXD3 RHBDF1 ZNF532 FRMPD1	1.81e-05	165	87	5	ebd668e87e5961a124d1d6fc25d1f03e4af05cd4
ToppCell	10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-CD4_INF-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FBLN7 FBXL8 PIM1 LAX1 ITK	1.86e-05	166	87	5	000faacc79b0bd279ddce4e692d801e7e2063ab6
ToppCell	facs-Brain_Non-Myeloid-Striatum-3m-Lymphocytic\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRAF1 SYTL3 PIM1 LAX1 ITK	1.97e-05	168	87	5	dc1143bd8db70c490167d73a525fd9b783eba960
ToppCell	facs-Brain_Non-Myeloid-Striatum-3m-Lymphocytic-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRAF1 SYTL3 PIM1 LAX1 ITK	1.97e-05	168	87	5	a75d63ae8ad64b5560853775f6df398feb314ce8
ToppCell	droplet-Fat-Bat-18m\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MEGF6 FBXL8 EVA1A SYBU BBS12	2.09e-05	170	87	5	c720d81bc29a8fd1f1249c6af408471d561f1d5d
ToppCell	droplet-Fat-Bat\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MEGF6 FBXL8 EVA1A SYBU BBS12	2.09e-05	170	87	5	c4ecdfc2b4710da0a5fbb20e9df02536023badb1
ToppCell	E16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	LHX2 MEGF6 SYTL3 LHX6 MUC2	2.09e-05	170	87	5	af8b56555cbd5a1016ab9ec2ce88225c58c89648
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	TRAF1 SYTL3 RORA YTHDC2 ITK	2.15e-05	171	87	5	2e9a20f8980b78325c52065a9c14ab3656267c05
ToppCell	facs-GAT-Fat-18m-Lymphocytic-T_cell\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRAF1 PIM1 RORA LAX1 ITK	2.21e-05	172	87	5	17a486c5d0430abb133eab9f087e2ef8b60f7d25
ToppCell	E16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MEGF6 SYTL3 LHX6 MUC2 EDA2R	2.21e-05	172	87	5	9a1743abcd5fbd38253ea84d88ad716cfb71de36
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Lymphocytic\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRAF1 SYTL3 PIM1 LAX1 ITK	2.34e-05	174	87	5	ecee7e012ccd7876fb9df8aa939f8eb05b0c2b13
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Lymphocytic-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRAF1 SYTL3 PIM1 LAX1 ITK	2.34e-05	174	87	5	693fc31bed0f560644e419fa70ef09f863425416
ToppCell	356C-Myeloid-Dendritic-cDC_proliferating_2\|Dendritic / Donor, Lineage, Cell class and subclass (all cells)	RNF34 ZFPM1 RAB3IL1 SH3RF3 ZNF367	2.40e-05	175	87	5	7de1023161233b64f11e130881c742f4cf2bff65
ToppCell	10x3'2.3-week_14-16-Lymphocytic_T-T_NK-Treg\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	FBLN7 TRAF1 RORA LAX1 ITK	2.47e-05	176	87	5	2eb1827171e9c19f945e87824215721f8cf22258
ToppCell	T_cells-TFH-like_cells\|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis	FBLN7 TRAF1 KSR2 WNT10A BBS12	2.60e-05	178	87	5	e2ae43e5ec31de6197f2cbd6089f944adbf0a163
ToppCell	BAL-Control-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	FBLN7 TRAF1 WNT10A RORA SYBU	2.67e-05	179	87	5	a634ca46ffc394c5f5215fc5d8eae4a77819af9c
ToppCell	Mild-Lymphoid-T-Treg\|Mild / Condition, Lineage, Cell class and cell subclass	FBLN7 TRAF1 RORA LAX1 ITK	2.67e-05	179	87	5	a7c01df7623aa6cee4ed4a341545ba240194ca8b
ToppCell	BAL-Control-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	FBLN7 TRAF1 WNT10A RORA SYBU	2.67e-05	179	87	5	35f014b6e752626909d829c5ab9bb761c1f3e3dc
ToppCell	droplet-Lung-3m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HTRA1 MEGF6 ACRBP CLU PLXNA4	2.82e-05	181	87	5	2c44c41b4e8a75ebdbaeb0c6cc5a03f17c44758c
ToppCell	facs-GAT-Fat-3m-Lymphocytic-T_cell\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRAF1 SYTL3 TAFA3 RORA ITK	2.90e-05	182	87	5	751bd3e3b49de961523e98197688a05c998c121a
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	TRAF1 SYTL3 RORA MAML2 ITK	2.97e-05	183	87	5	f2ef110bf29b1a8276ef216238363e542db262c1
ToppCell	wk_15-18-Epithelial-Distal_epithelial_progenitor-epi-tip_intermediate\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	NOP9 FBXL8 SGSM2 PLA2G6 SEMA4G	3.13e-05	185	87	5	636505a3d96f75d951ab42bcf8af6ae07abc732d
ToppCell	Fetal_29-31_weeks-Immune-natural_killer_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	TRAF1 SYTL3 XPO6 ZFPM1 ITK	3.38e-05	188	87	5	6686dbba990066568aa7573e70a7db8b4758f457
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_T-T4_reg\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	FBLN7 TRAF1 PIM1 RORA ITK	3.38e-05	188	87	5	e5c480b9a030536578f1cc91fb61738f752525b3
ToppCell	droplet-Limb_Muscle-nan-3m-Endothelial-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRIM46 ACRBP RECQL SYBU LHX6	3.47e-05	189	87	5	16a4c92dd7a0d60f3691bd3130a091a9a54730f1
ToppCell	severe_COVID-19-CD4+_Tcm\|World / disease group, cell group and cell class (v2)	FBLN7 FBXL8 PIM1 RORA ITK	3.47e-05	189	87	5	8037fd4d799d95d9ca633a3efaf698539f696893
ToppCell	normal_Lymph_Node-B_lymphocytes-Undetermined\|B_lymphocytes / Location, Cell class and cell subclass	FBLN7 SYTL3 RORA SH3RF3 ITK	3.56e-05	190	87	5	85cf147f2baf2e575073b4edab57c7809475268a
ToppCell	metastatic_Lymph_Node-T/NK_cells-Treg\|metastatic_Lymph_Node / Location, Cell class and cell subclass	FBLN7 TRAF1 RORA LAX1 ITK	3.56e-05	190	87	5	0523f1039b39a45a23f2f4444e5b47ed581fc4bb
ToppCell	COVID-19-Heart-T_cell\|Heart / Disease (COVID-19 only), tissue and cell type	SYTL3 ABCA13 KSR2 GRID2 ITK	3.56e-05	190	87	5	e6c3a6e01fef6c5b49f72661d4fb0414ba9046bf
ToppCell	droplet-Pancreas-PANCREAS-30m-Endothelial-nan\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MEGF6 KIF26A EVA1A PLXNA4 LHX6	3.65e-05	191	87	5	471205494b91be69926dc8159376132bcea0d9b5
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_T-T4_reg-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	FBLN7 TRAF1 PIM1 RORA ITK	3.65e-05	191	87	5	c5e22df4a8741b8096cdd1618271fd48d6265846
ToppCell	Control-Lymphoid-ILC_A\|Control / Disease state, Lineage and Cell class	SYTL3 XPO6 PLXNA4 ZFPM1 ITK	3.65e-05	191	87	5	1ca73582dc3d28322b5ee841010067589d848acc
ToppCell	BAL-Severe-Lymphocyte-T/NK-CD4+_T-Treg-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	FBLN7 SYTL3 RORA LAX1 ITK	3.74e-05	192	87	5	d85a785a12076e34c404171363a647f318926b18
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	TRAF1 SYTL3 RORA MAML2 ITK	3.74e-05	192	87	5	47646d7e4990be85072987f92bf18d52f8da752e
ToppCell	ILEUM-non-inflamed-(1)_Cytotoxic_CD8_Trm\|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	TRAF1 SYTL3 PIM1 RORA LAX1	3.74e-05	192	87	5	cc9287803cd979e4b81f0649527f1b3bf54d0b83
ToppCell	Control-Lymphoid-T\|World / Disease state, Lineage and Cell class	SYTL3 XPO6 RORA LAX1 ITK	3.74e-05	192	87	5	253cf4d2cf88ad8c45b73779336180840bef054b
ToppCell	Healthy_Control-Lymphoid-T-CCR7+_T\|Healthy_Control / Condition, Lineage, Cell class and cell subclass	FBLN7 PIM1 RORA LAX1 ITK	3.74e-05	192	87	5	5b197f65a87c315e4f50c77a7fdec3b342a863ad
ToppCell	normal_Pleural_Fluid-B_lymphocytes-Undetermined\|B_lymphocytes / Location, Cell class and cell subclass	FBLN7 SYTL3 PIM1 RORA ITK	3.74e-05	192	87	5	c13a438c46ee240e5832ec76880207451155c8df
ToppCell	BAL-Severe-Lymphocyte-T/NK-CD4+_T-Treg\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	FBLN7 SYTL3 RORA LAX1 ITK	3.74e-05	192	87	5	230f3090607a62bb6d1e1f4b0341ee96d93f1c00
ToppCell	moderate-Lymphoid-CTL\|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	TRAF1 SYTL3 RORA LAX1 ITK	3.83e-05	193	87	5	3fce0807631811da1cff5ca9db23ff1ad36020e7
ToppCell	Control-Lymphoid-T\|Control / Disease state, Lineage and Cell class	SYTL3 XPO6 RORA LAX1 ITK	3.83e-05	193	87	5	af928046ccd1ca874be1534aef6ca7f27d90bc46
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	FBLN7 HTRA1 PLXNA4 MCM5 ZNF367	3.83e-05	193	87	5	bbdfda6665941cfa1965418bb91ef9ff43b1326f
ToppCell	3'-Distal_airway-Immune_Lymphocytic-Lymphocytic_T/NK-CD4-positive,_alpha-beta_T_cell-CD4_T_cells\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FBLN7 SYTL3 PIM1 RORA ITK	3.83e-05	193	87	5	7022b3ce6220d6d1722a4e2947630a8da002cdce
ToppCell	3'-Distal_airway-Immune_Lymphocytic-Lymphocytic_T/NK-CD4-positive,_alpha-beta_T_cell-CD4_T_cells-CD4_T_cells_L.1.1.1.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FBLN7 SYTL3 PIM1 RORA ITK	3.83e-05	193	87	5	3083305b7ae09a37d7f45b915d49b2b396276822
ToppCell	3'-Distal_airway-Immune_Lymphocytic-Lymphocytic_T/NK-CD4-positive,_alpha-beta_T_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FBLN7 SYTL3 PIM1 RORA ITK	3.83e-05	193	87	5	1218e74ee5e00d230222b10acc50cb96201016b4
ToppCell	NS-moderate-d_16-33-Lymphoid-CTL\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	TRAF1 SYTL3 RORA LAX1 ITK	3.93e-05	194	87	5	6b2bb3dd11fd53fa9ab4d66c18b0714f96f99288
ToppCell	(1)_T_cells\|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)	TRAF1 SYTL3 PIM1 RORA ITK	3.93e-05	194	87	5	f9639f57976bbfff1d6140a542cd50a8b1ded2dc
ToppCell	3'-Pediatric_IBD-SmallIntestine-Hematopoietic-T_cells-Tfh\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FBLN7 TRAF1 KSR2 RORA ITK	4.02e-05	195	87	5	ea83c3c93ec4e09029185508bdbd6d9cc5e441d5
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_T_CD4-Trm_Th1/Th17\|lymph-node_spleen / Manually curated celltypes from each tissue	TRAF1 SYTL3 PIM1 RORA ITK	4.02e-05	195	87	5	c60982804a74dbe6607c021799ca74af2204aba8
ToppCell	COVID-19-Lymphoid-Tregs\|COVID-19 / Condition, Lineage and Cell class	FBLN7 SYTL3 RORA LAX1 ITK	4.02e-05	195	87	5	284cfff4d59ecc1430997b118de17fee167dcbb1
ToppCell	10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-Reg_T-Z\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FBLN7 TRAF1 WNT10A RORA LAX1	4.12e-05	196	87	5	9a28571e01d020e2ebe77690619182f4e4ffe696
ToppCell	Tracheal-10x5prime-Immune_Lymphocytic-T-T_CD4-T_reg\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	TRIM46 TRAF1 SYTL3 LAX1 ITK	4.12e-05	196	87	5	c0028307cf5dddfc4b5db1445fa83b74019a20bd
ToppCell	Bronchial-10x5prime-Immune_Lymphocytic-T-T_CD4-T_reg\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	FBLN7 TRAF1 WNT10A RORA ITK	4.12e-05	196	87	5	b60e5bf9a45c08e0ca12c7e2ac2009ea53e04f4e
ToppCell	Tracheal-10x5prime-Immune_Lymphocytic-T-T_CD4-CD4\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	TRAF1 SYTL3 RORA LAX1 ITK	4.22e-05	197	87	5	53b20c439b9473b49011cd175d2770f12c472fc3
ToppCell	T_cells-Treg_cells\|World / Immune cells in Kidney/Urine in Lupus Nephritis	FBLN7 TRAF1 KSR2 WNT10A ITK	4.22e-05	197	87	5	de5448fcdf4e433fc167496413abe5d0c8a5c6d8
ToppCell	5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD4-positive,_alpha-beta_T_cell-CD4_T_cells-CD4_T_cells_L.1.1.1.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FBLN7 TRAF1 PIM1 RORA ITK	4.33e-05	198	87	5	f6472649cf000918b98126cf02821d6779643292
ToppCell	Tracheal-10x5prime-Immune_Lymphocytic-T-T_CD4\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	TRAF1 SYTL3 RORA LAX1 ITK	4.33e-05	198	87	5	12cd44bc02c7577fbcf230957a1fecc1e5bfde37
ToppCell	Bronchial-10x5prime-Immune_Lymphocytic-T-T_CD4\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	FBLN7 TRAF1 SYTL3 RORA ITK	4.33e-05	198	87	5	8d86b5c875d4663ea4d61f50a4eaff1883d97641
ToppCell	systemic_lupus_erythematosus-managed-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	ACRBP CLU SYTL3 RORA ITK	4.33e-05	198	87	5	d51b255f8d5069232031d4825e0707fddf67d0a2
ToppCell	mild-Treg\|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	FBLN7 TRAF1 MEGF6 RORA ITK	4.33e-05	198	87	5	0269617c0628003d2a13dab98abfd2d15775d16a
ToppCell	Bronchus_Control_(B.)-Stromal-TX-Smooth_muscle-1\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	PDGFRB VSIG10L DGKB GRID2 EDA2R	4.33e-05	198	87	5	0f1feed8a37293ae02465909f99548ab58dc7ce5
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_T_CD4\|lymph-node_spleen / Manually curated celltypes from each tissue	FBLN7 PIM1 RORA MAML2 ITK	4.33e-05	198	87	5	2cbafcb03df3c9aca68371df500d18ab8dcc416c
ToppCell	Parenchymal-10x5prime-Immune_Lymphocytic-T-T_CD4-CD4\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	FBLN7 TRAF1 SYTL3 RORA ITK	4.33e-05	198	87	5	cdb4d65a125a57a98287761d049cc34e6ae1d6bf
ToppCell	10x5'v1-week_12-13-Myeloid_neutrophil-granulo-eo/baso/mast\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	EXD3 CLU SYTL3 KDM4C LAX1	4.33e-05	198	87	5	a1247a5efd92f95c6227c0e71dc8a0427eb54b7f
ToppCell	Parenchymal-10x5prime-Immune_Lymphocytic-T-T_CD4\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	FBLN7 TRAF1 SYTL3 RORA ITK	4.43e-05	199	87	5	e655cb92fe674b07096bb697d6befe0314ccbc5f
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW26\|fetalBrain_Zhong_nature / Sample Type, Dataset, Time_group, and Cell type.	EXD3 HTRA1 CLU SYBU LHX6	4.54e-05	200	87	5	61d7dd0a78942b069c3f5e75044368dc00e6e8e6
ToppCell	Neuronal-Inhibitory-iB-iB_2(PVALB)-SCUBE3\|Neuronal / cells hierarchy compared to all cells using T-Statistic	FBLN7 HTRA1 FRMPD1 RORA LHX6	4.54e-05	200	87	5	2441a36d363b799a4692aa697f969cda056c2d60
ToppCell	Bronchial-10x5prime-Immune_Lymphocytic-T-T_CD8\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	TRAF1 SYTL3 RORA LAX1 ITK	4.54e-05	200	87	5	8b8c07a16c91bd6e0d276fba1472d0d314e03416
ToppCell	10x5'-GI_large-bowel-Lymphocytic_T_CD4\|GI_large-bowel / Manually curated celltypes from each tissue	FBLN7 TRAF1 KSR2 RORA ITK	4.54e-05	200	87	5	42403d59b65d4b3ba6aa4aaf2d7252176067fba5
ToppCell	Sepsis-ICU-SEP-Lymphocyte-T/NK-CD4+_Tem\|ICU-SEP / Disease, condition lineage and cell class	CLEC18B MEGF6 FRMPD2 RORA ITK	4.54e-05	200	87	5	859d736dd29ce2dfcb51455e2343c18b87d9cd7a
ToppCell	Neuronal-Inhibitory-iB-iB_2(PVALB)-SCUBE3-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	FBLN7 HTRA1 FRMPD1 RORA LHX6	4.54e-05	200	87	5	c7bca638229bd4fd2414171e73fa949e36a10a92
ToppCell	Neuronal-Inhibitory-iB-iB_2(PVALB)-SCUBE3--L2-5\|Neuronal / cells hierarchy compared to all cells using T-Statistic	FBLN7 HTRA1 FRMPD1 RORA LHX6	4.54e-05	200	87	5	d841dbe2297c3bf62f49bae5921662cd6a47e5c2
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW26\|organoid_Tanaka_cellReport / Sample Type, Dataset, Time_group, and Cell type.	EXD3 HTRA1 CLU SYBU LHX6	4.54e-05	200	87	5	5c7263c862093ad9dbc81d06b16b6f74e8a6b634
ToppCell	droplet-Trachea-nan-3m-Mesenchymal-mesenchymal_cell\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBLN7 HTRA1 CLU PDGFRB	1.09e-04	126	87	4	c3261ea8726400de87f1c8a5a5134ba2b2884f66
ToppCell	TCGA-Prostate-Solid_Tissue_Normal-Prostate_normal_tissue-Prostate_normal_tissue-3\|TCGA-Prostate / Sample_Type by Project: Shred V9	VWA5B2 PATE3 EVA1A PKD1L2	1.34e-04	133	87	4	3e0e37dfb07a2de72e2b49f32ff201c3ec56f247
ToppCell	PBMC-Mild-cDC_2\|Mild / Compartment, Disease Groups and Clusters	PDGFRB PLXNA4 SYBU EDA2R	1.42e-04	135	87	4	cb9d834f8301cf53f20e09c3f4cb6a148690196a
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-4M-Neuronal-cortical_neurons_1\|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.	CLEC18A SLC26A8 SYBU SEMA4G	1.68e-04	141	87	4	73b3e967357cba7585d97ec9e9d48d3e94ebe31e
ToppCell	COVID-19-kidney-Technical/muscle_(PCT)\|kidney / Disease (COVID-19 only), tissue and cell type	SLC26A8 ABCA13 DGKB GRID2	1.92e-04	146	87	4	c55f1bdb6ac43b4118cb27ea7c879527e1afcbab
ToppCell	LPS-antiTNF-Hematopoietic_Mast-Mast_cells-T-cells\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SYTL3 WNT1 RORA ITK	1.97e-04	147	87	4	1ecd7c084e73eb6fae1ab1f9aae17115d3d62cbd
ToppCell	LPS-antiTNF-Hematopoietic_Mast-Mast_cells\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SYTL3 WNT1 RORA ITK	2.08e-04	149	87	4	59aa1f2a5cbeba64c4529fb05f544db17fd8b188
ToppCell	LPS-antiTNF-Hematopoietic_Mast\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SYTL3 WNT1 RORA ITK	2.08e-04	149	87	4	1527cdd98a2734cbf8ce4c6170557280b71c55cb
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-high_Fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PDGFRB CPT1C SH3RF3 LAX1	2.13e-04	150	87	4	1270f33f9d7e46e55adf1a96e8beee858b95589d
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-high_Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PDGFRB CPT1C SH3RF3 LAX1	2.13e-04	150	87	4	156118ce1d69522624196410cba18b8354cd0bb4
ToppCell	3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_T/NK-CD4-positive,_alpha-beta_T_cell-CD4_T_cells-CD4_T_cells_L.1.1.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TRAF1 SYTL3 RORA ITK	2.13e-04	150	87	4	207fc230d7721149c7afc7970dd56817f52801d8
Disease	bone morphogenetic protein 7 measurement	F12 ZNF367	3.38e-04	10	82	2	EFO_0020187
Disease	Impaired cognition	HTRA1 CLU	6.79e-04	14	82	2	C0338656
Disease	chemokine (C-C motif) ligand 27 measurement	KDM4C RORA F12	9.90e-04	70	82	3	EFO_0008082
Disease	acute lymphoblastic leukemia, response to antineoplastic agent	DGKB MAML2	1.27e-03	19	82	2	EFO_0000220, GO_0097327
Disease	HIV-1 infection, Susceptibility to viral and mycobacterial infections	KDM4C FRMPD1	1.55e-03	21	82	2	EFO_0000180, Orphanet_391311
Disease	proprotein convertase subtilisin/kexin type 9 measurement	KSR2 PCSK9	1.70e-03	22	82	2	EFO_0009312
Disease	Abnormality of refraction	CLU FRMPD2 KSR2 ZBTB4 WNT10A PLA2G6 RORA	2.70e-03	673	82	7	HP_0000539

Protein segments in the cluster

Peptide	Gene	Start	Entry
RCVAALARVECTHFL	ACOT7L	21	Q6ZUV0
RVSVRVCLSHLRCFE	ADCK2	6	Q7Z695
SRVVSRAAVHCALRS	AKR7A2	6	O43488
AETTCRLRATHGCRN	ACRBP	56	Q8NEB7
SDRVAVLQHGRLRCC	ABCA13	4041	Q86UQ4
RRFLQGRRCEHSTDC	DIPK1B	326	Q5VUD6
LADTCCRQSILIHSR	BBS12	221	Q6ZW61
TCALSGLTRTCRHRI	RAB3IL1	301	Q8TBN0
AALVIRISCHTDCRR	EVA1A	51	Q9H8M9
QCLTTCRSVRERESH	DEPDC5	476	O75140
SRAPRCAQVERAQHC	FBLN7	191	Q53RD9
SNLRTVACHRCGVHV	NOP9	131	Q86U38
VRAKATRISIQCRSC	MCM5	161	P33992
CSELSRHRVLRSLCS	NLRP10	401	Q86W26
CARLNASLSCLRNVH	KSR2	141	Q6VAB6
QRVRVARCCEDVCAH	MCM3AP	1201	O60318
QRCFRGNHRISSTLC	GRID2	296	O43424
AVTAVAICCRSRHLA	PCSK9	671	Q8NBP7
AICCRSRHLAQASQE	PCSK9	676	Q8NBP7
VLHSICSRRDACERA	PLXNA1	536	Q9UIW2
VLHNTCTRKERCERS	PLXNA4	531	Q9HCM2
RLRALNTCVSHICAV	OR51G1	236	Q8NGK1
RLHCRQIRLIGQSCT	MUC2	746	Q02817
SRTLCEACNIRFSRH	ZFPM1	681	Q8IX07
IFCRHRVKRVSGACI	KDM4C	811	Q9H3R0
AHCINVRASRDCASI	LAX1	171	Q8IWV1
CTVQTRAVACTRRRL	LINGO3	31	P0C6S8
SVQRCARCHLGISAS	LHX2	111	P50458
HVRCLECSVCRTSLR	LHX6	91	Q9UPM6
AERRCDVCATHLQQL	KIF26A	121	Q9ULI4
TCSKGTRTRRRACNH	CFP	151	P27918
RCARSSFTRVQRVSC	PKD1L2	1541	Q7Z442
LQCITCHLRTRTDRC	PATE3	21	B3GLJ2
RARIAVCRQHHLSCE	MAML2	41	Q8IZL2
TVRSCTREACNFVRA	CPT1C	601	Q8TCG5
SVTVRRHHCRQCGNI	EEA1	1366	Q15075
CSSHLLLRRAAVACL	HEATR5B	1076	Q9P2D3
VRRRAQAGLCVCASS	HTRA1	101	Q92743
RCAALREVHCFCVVS	FBXL8	326	Q96CD0
QFTDCSRCSARHREA	FRMPD1	1506	Q5SYB0
HRRCTLQSVLEACRV	FRMPD2	146	Q68DX3
RRSQDLHCGACRALV	CNPY2	21	Q9Y2B0
AGRRLAQCSCVVIRT	DGKB	736	Q9Y6T7
RCASGRCTVRDFIHR	SDE2	21	Q6IQ49
NCVHRDLAARNVLIC	PDGFRB	821	P09619
ACVIHRDLAARNCLV	ITK	476	Q08881
HCVQLTITRHRCQCR	MEGF6	216	O75095
RQRVSSECQHLIRWC	PIM1	256	P11309
RRNHSCEPCQTLAVR	F12	431	P00748
RVCAQCRVFLRGTHA	SYTL3	86	Q4VX76
AHRCCNRNRIEERSQ	TAFA3	51	Q7Z5A8
CQRLVCQLCRVRRTH	TRIM46	241	Q7Z4K8
CQLCRVRRTHSGHKI	TRIM46	246	Q7Z4K8
INITTFRHHVQCRCS	SLC26A8	51	Q96RN1
VQHRRRSVHLCCTKV	PRAMEF19	171	Q5SWL8
SAREREKHSACCVRN	RHBDF1	491	Q96CC6
ACARECVESLHQNSR	SGSM2	241	O43147
VCRVCNRATADIQRL	SPATA31D4	126	Q6ZUB0
IRECFHHSRIISCAN	PLA2G6	131	O60733
QVRCSLQCVHGRFRE	CLEC18A	261	A5D8T8
QVRCSLQCVHGRFRE	CLEC18B	261	Q6UXF7
QVRCSLQCVHGRFRE	CLEC18C	261	Q8NCF0
RCRVCSVRCHKFLVS	CLCN2	71	P51788
DRTVCREIRHNSTGC	CLU	281	P10909
RRFTRIAVDEVHCCS	RECQL	211	P46063
VCRVCNRATADIQRL	SPATA31D3	126	P0C874
ILITNVVCVFRTRCH	TBPL1	11	P62380
DRRSVRIEVTCNHCT	ZNF532	636	Q9HCE3
QSRSSHRVARVARVC	SEMA4G	256	Q9NTN9
HIRPVCRNARCTSIS	PIGT	221	Q969N2
LRRCSTCHLLQETAF	RNF34	96	Q969K3
LRRCISEQHRFVCDT	RREB1	306	Q92766
LIDRTSRNRCQHCRL	RORA	116	P35398
CCVVALHSLRRTAFR	SYBU	646	Q9NX95
TFCRRCLESIVCSRH	SH3RF3	76	Q8TEJ3
RTERRHRCGDCAQTF	ZBTB4	721	Q9P1Z0
VTRRCHESACGRTVS	TRAF1	276	Q13077
SGLLVSCACRRAHRR	SEMA6C	621	Q9H3T2
HNRRVALGITCVQCT	SKOR2	81	Q2VWA4
ACGRACSRLSTLIQH	ZNF517	456	Q6ZMY9
ECGRCFRQRTTLVNH	ZNF133	386	P52736
FCAAVRISQERLCRA	VWA5B2	1076	Q8N398
TRAHRIANIRCCSAV	YTHDC2	1041	Q9H6S0
TRTQRVTERCNCTFH	WNT1	336	P04628
CLARHLVATRTCTVT	VSIG10L	561	Q86VR7
HNILRQTRSERCHCR	WNT10A	381	Q9GZT5
ITAENDCRRLHCSLR	XPO6	541	Q96QU8
EHSSSRIRCNICNRV	ZNF367	161	Q7RTV3
HRCQSCITCAVINRV	EDA2R	56	Q9HAV5
VRVTHADIFSRCQAC	EXD3	716	Q8N9H8