Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	cytoskeletal motor activity	MYH15 KIFC2 KIFC3	1.82e-04	118	19	3	GO:0003774
GeneOntologyMolecularFunction	microtubule motor activity	KIFC2 KIFC3	1.99e-03	70	19	2	GO:0003777
GeneOntologyMolecularFunction	microtubule binding	KIFC2 CEP295NL KIFC3	2.93e-03	308	19	3	GO:0008017
GeneOntologyMolecularFunction	cytoskeletal protein binding	CACNA1D MYH15 KIFC2 CEP295NL KIFC3	3.04e-03	1099	19	5	GO:0008092
Domain	Kinesin_motor_CS	KIFC2 KIFC3	6.26e-04	41	17	2	IPR019821
Domain	Kinesin-like_fam	KIFC2 KIFC3	6.89e-04	43	17	2	IPR027640
Domain	KINESIN_MOTOR_1	KIFC2 KIFC3	7.21e-04	44	17	2	PS00411
Domain	Kinesin	KIFC2 KIFC3	7.21e-04	44	17	2	PF00225
Domain	-	KIFC2 KIFC3	7.21e-04	44	17	2	3.40.850.10
Domain	Kinesin_motor_dom	KIFC2 KIFC3	7.21e-04	44	17	2	IPR001752
Domain	KISc	KIFC2 KIFC3	7.21e-04	44	17	2	SM00129
Domain	KINESIN_MOTOR_2	KIFC2 KIFC3	7.21e-04	44	17	2	PS50067
Pubmed	Lunatic fringe potentiates Notch signaling in the developing brain.	NEUROG2 RORA	4.81e-05	19	19	2	20510365
Pubmed	The SSX gene family: characterization of 9 complete genes.	SSX4 SSX9P	5.90e-05	21	19	2	12216073
Pubmed	Identification and classification of 16 new kinesin superfamily (KIF) proteins in mouse genome.	KIFC2 KIFC3	8.42e-05	25	19	2	9275178
Pubmed	Sonic hedgehog signaling controls thalamic progenitor identity and nuclei specification in mice.	NEUROG2 RORA	8.42e-05	25	19	2	19357274
Pubmed	Identification, partial characterization, and genetic mapping of kinesin-like protein genes in mouse.	KIFC2 KIFC3	9.12e-05	26	19	2	9339368
Pubmed	Novel interactors and a role for supervillin in early cytokinesis.	HMMR KIFC3	1.06e-04	28	19	2	20309963
Pubmed	Genome-wide characterisation of Foxa1 binding sites reveals several mechanisms for regulating neuronal differentiation in midbrain dopamine cells.	NEUROG2 RORA	1.22e-04	30	19	2	25804738
Pubmed	Developmental trajectories of thalamic progenitors revealed by single-cell transcriptome profiling and Shh perturbation.	NEUROG2 RORA	1.30e-04	31	19	2	36476860
Pubmed	Molecular mapping of developing dorsal horn-enriched genes by microarray and dorsal/ventral subtractive screening.	RORA CYRIA	1.39e-04	32	19	2	16516881
Pubmed	Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing.	NSRP1 CYRIA TXLNA CSTF2T	1.64e-04	523	19	4	11256614
Pubmed	Chromatin Remodeling BAF155 Subunit Regulates the Genesis of Basal Progenitors in Developing Cortex.	NEUROG2 SMARCC1	1.96e-04	38	19	2	30240734
Pubmed	Tissue-Specific Actions of Pax6 on Proliferation and Differentiation Balance in Developing Forebrain Are Foxg1 Dependent.	NEUROG2 RORA	2.07e-04	39	19	2	30529950
Pubmed	Dynamic spatiotemporal gene expression in embryonic mouse thalamus.	NEUROG2 RORA	2.29e-04	41	19	2	21192082
Pubmed	Network-based prediction of protein interactions.	TXLNA KIFC3	2.64e-04	44	19	2	30886144
Pubmed	Wnt/β-catenin signaling regulates sequential fate decisions of murine cortical precursor cells.	NEUROG2 RORA	2.88e-04	46	19	2	25182747
Pubmed	The Brd4 extraterminal domain confers transcription activation independent of pTEFb by recruiting multiple proteins, including NSD3.	SMARCC1 NSRP1	4.43e-04	57	19	2	21555454
Pubmed	Histone-binding of DPF2 mediates its repressive role in myeloid differentiation.	SMARCC1 NSRP1 CSTF2T	4.69e-04	283	19	3	28533407
Pubmed	ATG5 is required for B cell polarization and presentation of particulate antigens.	SMARCC1 NSRP1 TXLNA CSTF2T	4.98e-04	701	19	4	30196744
Interaction	CCDC146 interactions	MIPOL1 TXLNA KIFC3	6.00e-05	82	19	3	int:CCDC146
Interaction	SMARCE1 interactions	MIPOL1 SMARCC1 TXLNA KIFC3	1.32e-04	287	19	4	int:SMARCE1
Interaction	ANKRD23 interactions	MIPOL1 KIFC3	1.75e-04	21	19	2	int:ANKRD23
Interaction	NDC80 interactions	NSRP1 TXLNA HMMR KIFC3	1.82e-04	312	19	4	int:NDC80
Interaction	CDK18 interactions	MIPOL1 NSRP1 KIFC3	2.41e-04	131	19	3	int:CDK18
Interaction	OLIG2 interactions	NEUROG2 TXLNA	2.49e-04	25	19	2	int:OLIG2
Interaction	CDR2 interactions	SSX4 TXLNA KIFC3	2.75e-04	137	19	3	int:CDR2
Cytoband	Xp11.23	SSX4 SSX9P	7.08e-04	95	19	2	Xp11.23
Cytoband	Ensembl 112 genes in cytogenetic band chr3p21	SMARCC1 CACNA1D	7.48e-03	316	19	2	chr3p21
Cytoband	Ensembl 112 genes in cytogenetic band chrXp11	SSX4 SSX9P	1.05e-02	377	19	2	chrXp11
GeneFamily	Kinesins\|Pleckstrin homology domain containing	KIFC2 KIFC3	4.11e-04	46	12	2	622
Coexpression	TURASHVILI_BREAST_DUCTAL_CARCINOMA_VS_LOBULAR_NORMAL_UP	RORA CSTF2T HMMR	2.03e-05	74	19	3	M4479
Disease	eosinophilic esophagitis	RORA CEP295NL ADGRL3	8.79e-05	163	16	3	EFO_0004232
Disease	late-onset Alzheimers disease	CYRIA CEP295NL KIFC3	4.88e-04	292	16	3	EFO_1001870
Disease	lifestyle measurement, anxiety disorder measurement	SMARCC1 RORA	2.46e-03	137	16	2	EFO_0007795, EFO_0010724
Disease	Stuttering	RORA CYRIA	2.68e-03	143	16	2	HP_0025268
Disease	respiratory system disease	RORA CEP295NL	2.75e-03	145	16	2	EFO_0000684
Disease	brain measurement, neuroimaging measurement	NEUROG2 RORA CYRIA	3.01e-03	550	16	3	EFO_0004346, EFO_0004464
Disease	refractive error, age at onset, Myopia	CACNA1D CYRIA	4.81e-03	193	16	2	EFO_0004847, HP_0000545, MONDO_0004892
Disease	Abnormality of refraction	CACNA1D RORA ADGRL3	5.30e-03	673	16	3	HP_0000539
Disease	cognitive function measurement	MIPOL1 CACNA1D MYH15 CYRIA	6.32e-03	1434	16	4	EFO_0008354
Disease	cortical surface area measurement, neuroimaging measurement	RORA CYRIA	6.59e-03	227	16	2	EFO_0004346, EFO_0010736
Disease	Liver Cirrhosis, Experimental	DIO1 SMARCC1 CYRIA	7.80e-03	774	16	3	C0023893
Disease	obsolete aging	SMARCC1 CYRIA	9.80e-03	279	16	2	GO_0007568

Protein segments in the cluster

Peptide	Gene	Start	Entry
DDDRHSQMIRDQQQQ	CEP295NL	581	Q96MC4
NNHERSSEQNRNLMN	ADGRL3	1251	Q9HAR2
REDQHQQKQSRDQEN	NSRP1	316	Q9H0G5
RINNMHLDIENEVNN	CYRIA	166	Q9H0Q0
KANNRERNRMHNLNA	NEUROG2	116	Q9H2A3
NNMRHLTAENNQERA	MIPOL1	296	Q8TD10
RNREHNENLNAEMQN	HMMR	306	O75330
KNNMDIRNHQNLQDR	DIO1	166	P49895
VQNSHQEARNMLLQN	CSTF2T	151	Q9H0L4
AMRDNNQINRNNNFQ	CACNA1D	1376	Q01668
QETEQNCRRELQQMH	KIFC2	316	Q96AC6
QARNQHLQEQVAMQR	KIFC3	276	Q9BVG8
ANNAFQDMLHNRENQ	MYH15	176	Q9Y2K3
ELRARQQMEQQQHGQ	SMARCC1	951	Q92922
QKHRMQQQQRDHQQQ	RORA	161	P35398
NDRNHRNQVERPQMT	SSX4	86	O60224
NDRNHRNQVERSQMT	SSX9P	86	Q7RTT3
ENQNIDDQHQNLRRN	ZNF44	96	P15621
LNDIQLQMEQHNERN	TXLNA	281	P40222