Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ATP hydrolysis activity	MYO1E MCM7 CHD3 KIF7 IFIH1 CHTF18 ATP11C ABCD1 POLQ KIF13A DNAH11	3.51e-05	441	111	11	GO:0016887
GeneOntologyMolecularFunction	ATP-dependent activity	MYO1E MYO7A MYO9A MCM7 CHD3 KIF7 IFIH1 CHTF18 ATP11C ABCD1 POLQ KIF13A DNAH11	3.68e-05	614	111	13	GO:0140657
GeneOntologyMolecularFunction	cytoskeletal motor activity	MYO1E MYO7A MYO9A KIF7 KIF13A DNAH11	5.12e-05	118	111	6	GO:0003774
GeneOntologyMolecularFunction	high voltage-gated calcium channel activity	CACNB1 CACNB3 CACNB4	5.82e-05	14	111	3	GO:0008331
GeneOntologyMolecularFunction	single-stranded DNA helicase activity	MCM7 CHTF18 POLQ	2.73e-04	23	111	3	GO:0017116
GeneOntologyMolecularFunction	actin filament binding	VIL1 MYO1E MYO7A MYO9A SPTB ACTN2 ACTN3	2.79e-04	227	111	7	GO:0051015
GeneOntologyMolecularFunction	1-phosphatidylinositol-4-phosphate 3-kinase activity	PIK3C2A PIK3CG	6.32e-04	7	111	2	GO:0035005
GeneOntologyMolecularFunction	1-phosphatidylinositol-4,5-bisphosphate 3-kinase activity	PIK3C2A PIK3CG	6.32e-04	7	111	2	GO:0046934
GeneOntologyMolecularFunction	phospholipase D activity	GPLD1 FAM83B	8.39e-04	8	111	2	GO:0004630
GeneOntologyCellularComponent	microtubule associated complex	NME8 KIF7 NDEL1 KIF13A FBXW11 DNAH11	2.32e-04	161	112	6	GO:0005875
GeneOntologyCellularComponent	condensed chromosome	CENPF ESRRB NUP98 SIN3A TEX11 NDEL1 MTBP FBXW11	2.51e-04	307	112	8	GO:0000793
GeneOntologyCellularComponent	kinetochore	CENPF NUP98 SIN3A NDEL1 MTBP FBXW11	4.34e-04	181	112	6	GO:0000776
GeneOntologyCellularComponent	chromosomal region	CENPF NUP98 MCM7 SIN3A NDEL1 MTBP TNKS TNKS2 FBXW11	4.42e-04	421	112	9	GO:0098687
GeneOntologyCellularComponent	supramolecular fiber	COL6A3 ANK1 MYO9A KRT81 KRT83 KRT86 STYXL2 ACTN2 ACTN3 KIF7 JUP RADIL NDEL1 KIF13A FBXW11 DNAH11	5.41e-04	1179	112	16	GO:0099512
GeneOntologyCellularComponent	supramolecular polymer	COL6A3 ANK1 MYO9A KRT81 KRT83 KRT86 STYXL2 ACTN2 ACTN3 KIF7 JUP RADIL NDEL1 KIF13A FBXW11 DNAH11	5.83e-04	1187	112	16	GO:0099081
GeneOntologyCellularComponent	condensed chromosome, centromeric region	CENPF NUP98 SIN3A NDEL1 MTBP FBXW11	6.10e-04	193	112	6	GO:0000779
GeneOntologyCellularComponent	cortical cytoskeleton	ANK1 MYO1E SPTB ACTN2 ACTN3	6.55e-04	129	112	5	GO:0030863
GeneOntologyCellularComponent	spectrin-associated cytoskeleton	ANK1 SPTB	9.99e-04	9	112	2	GO:0014731
GeneOntologyCellularComponent	polymeric cytoskeletal fiber	MYO9A KRT81 KRT83 KRT86 ACTN2 ACTN3 KIF7 JUP RADIL NDEL1 KIF13A FBXW11 DNAH11	1.05e-03	899	112	13	GO:0099513
GeneOntologyCellularComponent	microtubule organizing center	CCDC14 CEP104 RAN CENPF CHD3 CCDC141 TRIP4 KIF7 NDEL1 TNKS TNKS2 KIF13A FBXW11	1.28e-03	919	112	13	GO:0005815
GeneOntologyCellularComponent	unconventional myosin complex	MYO7A MYO9A	1.52e-03	11	112	2	GO:0016461
GeneOntologyCellularComponent	cortical actin cytoskeleton	MYO1E SPTB ACTN2 ACTN3	1.58e-03	93	112	4	GO:0030864
GeneOntologyCellularComponent	L-type voltage-gated calcium channel complex	CACNB1 CACNB3	1.81e-03	12	112	2	GO:1990454
GeneOntologyCellularComponent	voltage-gated calcium channel complex	CACNB1 CACNB3 CACNB4	1.92e-03	46	112	3	GO:0005891
HumanPheno	Perifollicular hyperkeratosis	KRT81 KRT83 KRT86	3.12e-06	4	48	3	HP:0007468
HumanPheno	Abnormal perifollicular morphology	KRT81 KRT83 KRT86	1.54e-05	6	48	3	HP:0031285
Domain	VDCC_L_bsu	CACNB1 CACNB3 CACNB4	8.36e-07	4	112	3	IPR000584
Domain	VGCC_beta4Aa_N	CACNB1 CACNB3 CACNB4	8.36e-07	4	112	3	PF12052
Domain	P-loop_NTPase	RAN CACNB1 CACNB3 CACNB4 MYO1E MYO7A MYO9A SPEF2 MCM7 CHD3 PFKFB1 KIF7 IFIH1 CHTF18 ABCD1 POLQ KIF13A DNAH11	2.85e-06	848	112	18	IPR027417
Domain	Spectrin	SPTB ACTN2 ACTN3 CCDC141	9.94e-06	23	112	4	PF00435
Domain	Spectrin_repeat	SPTB ACTN2 ACTN3 CCDC141	2.59e-05	29	112	4	IPR002017
Domain	-	RAN CACNB1 CACNB3 CACNB4 MYO1E MYO7A SPEF2 MCM7 CHD3 PFKFB1 IFIH1 CHTF18 ABCD1 POLQ DNAH11	3.90e-05	746	112	15	3.40.50.300
Domain	Oest-rel_rcp	ESRRB ESRRG	1.07e-04	3	112	2	IPR027289
Domain	SH3	CACNB1 CACNB3 CACNB4 MYO1E MYO7A ASAP2 DNMBP	3.26e-04	216	112	7	SM00326
Domain	SH3	CACNB1 CACNB3 CACNB4 MYO1E MYO7A ASAP2 DNMBP	3.26e-04	216	112	7	PS50002
Domain	ACTININ_2	SPTB ACTN2 ACTN3	3.41e-04	23	112	3	PS00020
Domain	ACTININ_1	SPTB ACTN2 ACTN3	3.41e-04	23	112	3	PS00019
Domain	Actinin_actin-bd_CS	SPTB ACTN2 ACTN3	3.41e-04	23	112	3	IPR001589
Domain	Oest_rcpt/oest-rel_rcp	ESRRB ESRRG	3.52e-04	5	112	2	IPR024178
Domain	SH3_domain	CACNB1 CACNB3 CACNB4 MYO1E MYO7A ASAP2 DNMBP	3.64e-04	220	112	7	IPR001452
Domain	Keratin_2_head	KRT81 KRT83 KRT86	3.88e-04	24	112	3	IPR032444
Domain	Keratin_2_head	KRT81 KRT83 KRT86	3.88e-04	24	112	3	PF16208
Domain	Guanylate_kin	CACNB1 CACNB3 CACNB4	4.94e-04	26	112	3	PF00625
Domain	Keratin_II	KRT81 KRT83 KRT86	4.94e-04	26	112	3	IPR003054
Domain	GK/Ca_channel_bsu	CACNB1 CACNB3 CACNB4	4.94e-04	26	112	3	IPR008145
Domain	Guanylate_kin-like_dom	CACNB1 CACNB3 CACNB4	4.94e-04	26	112	3	IPR008144
Domain	GuKc	CACNB1 CACNB3 CACNB4	4.94e-04	26	112	3	SM00072
Domain	EFhand_Ca_insen	ACTN2 ACTN3	5.26e-04	6	112	2	PF08726
Domain	EF-hand_Ca_insen	ACTN2 ACTN3	5.26e-04	6	112	2	IPR014837
Domain	PI3K_Ras-bd_dom	PIK3C2A PIK3CG	7.34e-04	7	112	2	IPR000341
Domain	PI3K_rbd	PIK3C2A PIK3CG	7.34e-04	7	112	2	SM00144
Domain	PI3K_rbd	PIK3C2A PIK3CG	7.34e-04	7	112	2	PF00794
Domain	PI3K_RBD	PIK3C2A PIK3CG	7.34e-04	7	112	2	PS51546
Domain	Ubiquitin-rel_dom	MYO7A MYO9A RADIL UBTD1 PIK3C2A PIK3CG	8.50e-04	184	112	6	IPR029071
Domain	FN3	FNDC3B COL6A3 FSD2 PTPRG PRLR EPHA1	8.74e-04	185	112	6	SM00060
Domain	SPEC	SPTB ACTN2 ACTN3	9.17e-04	32	112	3	SM00150
Domain	Spectrin/alpha-actinin	SPTB ACTN2 ACTN3	9.17e-04	32	112	3	IPR018159
Domain	CH	SPEF2 SPTB ACTN2 ACTN3	9.70e-04	73	112	4	PS50021
Domain	PI3K_C2	PIK3C2A PIK3CG	9.75e-04	8	112	2	SM00142
Domain	PI3K_C2_dom	PIK3C2A PIK3CG	9.75e-04	8	112	2	IPR002420
Domain	PI3K_C2	PIK3C2A PIK3CG	9.75e-04	8	112	2	PF00792
Domain	PI3K_C2	PIK3C2A PIK3CG	9.75e-04	8	112	2	PS51547
Domain	CH-domain	SPEF2 SPTB ACTN2 ACTN3	1.07e-03	75	112	4	IPR001715
Domain	PI3Ka	PIK3C2A PIK3CG	1.25e-03	9	112	2	PF00613
Domain	PI3Ka	PIK3C2A PIK3CG	1.25e-03	9	112	2	SM00145
Domain	-	PIK3C2A PIK3CG	1.25e-03	9	112	2	1.25.40.70
Domain	FN3	FNDC3B COL6A3 FSD2 PTPRG PRLR EPHA1	1.27e-03	199	112	6	PS50853
Domain	Myosin_head_motor_dom	MYO1E MYO7A MYO9A	1.52e-03	38	112	3	IPR001609
Domain	MYOSIN_MOTOR	MYO1E MYO7A MYO9A	1.52e-03	38	112	3	PS51456
Domain	Myosin_head	MYO1E MYO7A MYO9A	1.52e-03	38	112	3	PF00063
Domain	MYSc	MYO1E MYO7A MYO9A	1.52e-03	38	112	3	SM00242
Domain	PI_Kinase	PIK3C2A PIK3CG	1.55e-03	10	112	2	IPR015433
Domain	PInositide-3_kin_accessory_dom	PIK3C2A PIK3CG	1.55e-03	10	112	2	IPR001263
Domain	Retinoid-X_rcpt/HNF4	ESRRB ESRRG	1.55e-03	10	112	2	IPR000003
Domain	Ank_3	ANK1 TNKS	1.55e-03	10	112	2	PF13606
Domain	PIK_HELICAL	PIK3C2A PIK3CG	1.55e-03	10	112	2	PS51545
Domain	FN3_dom	FNDC3B COL6A3 FSD2 PTPRG PRLR EPHA1	1.63e-03	209	112	6	IPR003961
Domain	fn3	FNDC3B FSD2 PTPRG PRLR EPHA1	2.94e-03	162	112	5	PF00041
Domain	SH3_1	CACNB1 CACNB4 MYO1E ASAP2 DNMBP	3.10e-03	164	112	5	PF00018
Domain	PI3/4_kinase_CS	PIK3C2A PIK3CG	3.56e-03	15	112	2	IPR018936
Domain	-	PIK3C2A PIK3CG	4.05e-03	16	112	2	1.10.1070.11
Domain	Laminin_N	LAMB4 LAMA1	4.05e-03	16	112	2	IPR008211
Domain	PI3Kc	PIK3C2A PIK3CG	4.05e-03	16	112	2	SM00146
Domain	LamNT	LAMB4 LAMA1	4.05e-03	16	112	2	SM00136
Domain	LAMININ_NTER	LAMB4 LAMA1	4.05e-03	16	112	2	PS51117
Domain	Laminin_N	LAMB4 LAMA1	4.05e-03	16	112	2	PF00055
Domain	Poly(ADP-ribose)pol_cat_dom	TNKS TNKS2	4.57e-03	17	112	2	IPR012317
Domain	PARP_CATALYTIC	TNKS TNKS2	4.57e-03	17	112	2	PS51059
Domain	PARP	TNKS TNKS2	4.57e-03	17	112	2	PF00644
Domain	-	TNKS TNKS2	4.57e-03	17	112	2	3.90.228.10
Domain	PI3_PI4_kinase	PIK3C2A PIK3CG	5.12e-03	18	112	2	PF00454
Domain	PI3_4_KINASE_1	PIK3C2A PIK3CG	5.12e-03	18	112	2	PS00915
Domain	PI3_4_KINASE_2	PIK3C2A PIK3CG	5.12e-03	18	112	2	PS00916
Domain	PI3/4_kinase_cat_dom	PIK3C2A PIK3CG	5.12e-03	18	112	2	IPR000403
Domain	PI3_4_KINASE_3	PIK3C2A PIK3CG	5.12e-03	18	112	2	PS50290
Pathway	KEGG_ARRHYTHMOGENIC_RIGHT_VENTRICULAR_CARDIOMYOPATHY_ARVC	CACNB1 CACNB3 CACNB4 ACTN2 ACTN3 JUP	7.01e-06	74	89	6	M16376
Pathway	WP_ARRHYTHMOGENIC_RIGHT_VENTRICULAR_CARDIOMYOPATHY	CACNB1 CACNB3 CACNB4 ACTN2 ACTN3 JUP	7.01e-06	74	89	6	M39462
Pathway	KEGG_FOCAL_ADHESION	COL6A3 LAMB4 LAMA1 BIRC3 ACTN2 ACTN3 PIK3CG MAPK9	3.64e-05	199	89	8	M7253
Pathway	REACTOME_PRESYNAPTIC_DEPOLARIZATION_AND_CALCIUM_CHANNEL_OPENING	CACNB1 CACNB3 CACNB4	3.87e-05	11	89	3	MM14498
Pathway	REACTOME_PRESYNAPTIC_DEPOLARIZATION_AND_CALCIUM_CHANNEL_OPENING	CACNB1 CACNB3 CACNB4	3.87e-05	11	89	3	M26913
Pathway	REACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH	COL6A3 CACNB1 CACNB3 CACNB4 SPTB	4.72e-05	63	89	5	M11187
Pathway	REACTOME_NERVOUS_SYSTEM_DEVELOPMENT	COL6A3 CACNB1 CACNB3 CACNB4 CLTCL1 ARHGEF28 ANK1 SPTB LAMA1 RPL10A AP2S1 SEMA6D EPHA1	6.16e-05	575	89	13	M29853
Pathway	REACTOME_DEVELOPMENTAL_BIOLOGY	COL6A3 ARHGEF28 ANK1 KRT81 KRT83 KRT86 SPTB SIN3A JUP AP2S1 SEMA6D EPHA1	7.14e-05	502	89	12	MM14537
Pathway	REACTOME_NCAM1_INTERACTIONS	COL6A3 CACNB1 CACNB3 CACNB4	1.38e-04	42	89	4	M7169
Pathway	KEGG_MEDICUS_REFERENCE_CARDIAC_TYPE_VGCC_RYR_SIGNALING	CACNB1 CACNB3 CACNB4	2.98e-04	21	89	3	M47950
Pathway	KEGG_MEDICUS_REFERENCE_SKELETAL_TYPE_VGCC_RYR_SIGNALING	CACNB1 CACNB3 CACNB4	2.98e-04	21	89	3	M47949
Pathway	KEGG_MEDICUS_REFERENCE_DNA_REPLICATION_LICENSING	MCM7 DBF4 MTBP	4.47e-04	24	89	3	M47857
Pathway	REACTOME_DEVELOPMENTAL_BIOLOGY	COL6A3 CACNB1 CACNB3 CACNB4 CLTCL1 ARHGEF28 ANK1 KRT81 KRT83 KRT86 SPTB LAMA1 CHD3 SIN3A RPL10A JUP AP2S1 SEMA6D TRPM1 EPHA1	5.00e-04	1432	89	20	M509
Pathway	KEGG_MEDICUS_REFERENCE_CA2_ENTRY_VOLTAGE_GATED_CA2_CHANNEL	CACNB1 CACNB3 CACNB4	5.06e-04	25	89	3	M47948
Pubmed	Large-scale mapping of human protein-protein interactions by mass spectrometry.	VIL1 SPTLC1 NUP98 NASP MCM7 GPATCH8 MEST IBTK JUP RADIL ASAP2 AP2S1 GANAB RHPN2 POLR1E MTR POLQ FBXW11 HDLBP	3.29e-08	1284	113	19	17353931
Pubmed	Novel KRT83 and KRT86 mutations associated with monilethrix.	KRT81 KRT83 KRT86	3.34e-08	3	113	3	25557232
Pubmed	Regional expression and subcellular localization of the voltage-gated calcium channel β subunits in the developing mouse brain.	CACNB1 CACNB3 CACNB4	3.34e-08	3	113	3	22737983
Pubmed	Structure and site of expression of a murine type II hair keratin.	KRT81 KRT83 KRT86	3.34e-08	3	113	3	1372089
Pubmed	Transient expression of mouse hair keratins in transfected HeLa cells: interactions between "hard" and "soft" keratins.	KRT81 KRT83 KRT86	3.34e-08	3	113	3	1712823
Pubmed	Reciprocal interactions regulate targeting of calcium channel beta subunits and membrane expression of alpha1 subunits in cultured hippocampal neurons.	CACNB1 CACNB3 CACNB4	1.33e-07	4	113	3	19996312
Pubmed	Mutations of calcium channel beta subunit genes in mice.	CACNB1 CACNB3 CACNB4	1.33e-07	4	113	3	10494839
Pubmed	Keratins of the human hair follicle.	KRT81 KRT83 KRT86	1.33e-07	4	113	3	15797458
Pubmed	Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.	ARHGEF28 MYO9A KRT81 KRT86 SPTLC1 NUP98 NASP MCM7 CCNT2 RADIL ASAP2 GANAB TNKS TNKS2 DNMBP	2.98e-07	916	113	15	32203420
Pubmed	Role of the beta(2) subunit of voltage-dependent calcium channels in the retinal outer plexiform layer.	CACNB1 CACNB3 CACNB4	3.32e-07	5	113	3	11980879
Pubmed	Diversity and developmental expression of L-type calcium channel beta2 proteins and their influence on calcium current in murine heart.	CACNB1 CACNB3 CACNB4	3.32e-07	5	113	3	19723630
Pubmed	beta subunit reshuffling modifies N- and P/Q-type Ca2+ channel subunit compositions in lethargic mouse brain.	CACNB1 CACNB3 CACNB4	6.63e-07	6	113	3	10328888
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	FNDC3B COL6A3 SPTB ESRRG FSD2 ACTN2 ACTN3 CCDC141 PIK3C2A TNKS TNKS2	7.13e-07	497	113	11	23414517
Pubmed	The parafibromin tumor suppressor protein interacts with actin-binding proteins actinin-2 and actinin-3.	CLTCL1 ACTN2 ACTN3	1.85e-06	8	113	3	18687124
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	RAN CACNB4 MYO1E MYO7A MYO9A SPTB CHD3 ACTN2 ACTN3 RPL10A JUP AP2S1 NDEL1 MTMR2 TMED9 DNAH11 HDLBP	3.81e-06	1431	113	17	37142655
Pubmed	The protein network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1.	CENPF MCM7 GPATCH8 CCNT2 GANAB TNKS ABCD1	3.91e-06	197	113	7	20811636
Pubmed	A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies.	CEP104 KRT81 KRT83 KRT86 JUP ASAP2 HOXC9 CHTF18	4.37e-06	284	113	8	29459677
Pubmed	NCAM induces CaMKIIalpha-mediated RPTPalpha phosphorylation to enhance its catalytic activity and neurite outgrowth.	CACNB1 CACNB3 CACNB4	5.41e-06	11	113	3	18809727
Pubmed	Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.	DENND5B ARHGEF28 ESRRG RALGAPB SPTLC1 NASP GPATCH8 RPL10A CCNT2 AP2S1 GANAB POLR1E DBF4 TMED9 MTBP HDLBP	6.28e-06	1327	113	16	32694731
Pubmed	Characterization of a 300 kbp region of human DNA containing the type II hair keratin gene domain.	KRT81 KRT83 KRT86	7.19e-06	12	113	3	10692104
Pubmed	The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.	USP34 FNDC3B SPTLC1 MCM7 SIN3A GPATCH8 RPL10A CCNT2 JUP AP2S1 GANAB ZNF644 TMED9 TNKS ABCD1	8.46e-06	1203	113	15	29180619
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	RALGAPB NUP98 NASP CHD3 SIN3A GPATCH8 CCNT2 DBF4 CHTF18 ZNF644 DNMBP HDLBP	8.61e-06	774	113	12	15302935
Pubmed	Quantitative nanoproteomics for protein complexes (QNanoPX) related to estrogen transcriptional action.	RAN CLTCL1 SIN3A JUP	9.75e-06	41	113	4	19805454
Pubmed	Critical role for the beta regulatory subunits of Cav channels in T lymphocyte function.	CACNB3 CACNB4	1.05e-05	2	113	2	17028169
Pubmed	Tankyrase is necessary for canonical Wnt signaling during kidney development.	TNKS TNKS2	1.05e-05	2	113	2	20549720
Pubmed	Expression of estrogen-related receptors in ovarian cancer and impact on survival.	ESRRB ESRRG	1.05e-05	2	113	2	34089362
Pubmed	Ba2+ currents in inner and outer hair cells of mice lacking the voltage-dependent Ca2+ channel subunits beta3 or beta4.	CACNB3 CACNB4	1.05e-05	2	113	2	19755851
Pubmed	Tankyrase Requires SAM Domain-Dependent Polymerization to Support Wnt-β-Catenin Signaling.	TNKS TNKS2	1.05e-05	2	113	2	27494558
Pubmed	Mutational characteristics of ANK1 and SPTB genes in hereditary spherocytosis.	ANK1 SPTB	1.05e-05	2	113	2	26830532
Pubmed	A missense mutation in the type II hair keratin hHb3 is associated with monilethrix.	KRT83 KRT86	1.05e-05	2	113	2	15744029
Pubmed	Strength, power, fiber types, and mRNA expression in trained men and women with different ACTN3 R577X genotypes.	ACTN2 ACTN3	1.05e-05	2	113	2	19150855
Pubmed	Spectrin and ankyrin-based pathways: metazoan inventions for integrating cells into tissues.	ANK1 SPTB	1.05e-05	2	113	2	11427698
Pubmed	α-Actinin-2 deficiency results in sarcomeric defects in zebrafish that cannot be rescued by α-actinin-3 revealing functional differences between sarcomeric isoforms.	ACTN2 ACTN3	1.05e-05	2	113	2	22253474
Pubmed	Regulation of tankyrase activity by a catalytic domain dimer interface.	TNKS TNKS2	1.05e-05	2	113	2	30055800
Pubmed	alpha-actinin-3 and performance.	ACTN2 ACTN3	1.05e-05	2	113	2	19696509
Pubmed	Negative regulation of prolactin receptor stability and signaling mediated by SCF(beta-TrCP) E3 ubiquitin ligase.	PRLR FBXW11	1.05e-05	2	113	2	15082796
Pubmed	A variable monilethrix phenotype associated with a novel mutation, Glu402Lys, in the helix termination motif of the type II hair keratin hHb1.	KRT81 KRT86	1.05e-05	2	113	2	9665406
Pubmed	Differential regulation of Actn2 and Actn3 expression during unfolded protein response in C2C12 myotubes.	ACTN2 ACTN3	1.05e-05	2	113	2	32451822
Pubmed	Cloning and characterization of two human skeletal muscle alpha-actinin genes located on chromosomes 1 and 11.	ACTN2 ACTN3	1.05e-05	2	113	2	1339456
Pubmed	Molecular insights on TNKS1/TNKS2 and inhibitor-IWR1 interactions.	TNKS TNKS2	1.05e-05	2	113	2	24291818
Pubmed	A new mutation in the type II hair cortex keratin hHb1 involved in the inherited hair disorder monilethrix.	KRT81 KRT86	1.05e-05	2	113	2	9402962
Pubmed	Tankyrase 1 and tankyrase 2 are essential but redundant for mouse embryonic development.	TNKS TNKS2	1.05e-05	2	113	2	18612384
Pubmed	Ankyrin binds to two distinct cytoplasmic domains of Na,K-ATPase alpha subunit.	ANK1 SPTB	1.05e-05	2	113	2	8159688
Pubmed	Proteomic Analysis of the Human Tankyrase Protein Interaction Network Reveals Its Role in Pexophagy.	TNKS TNKS2	1.05e-05	2	113	2	28723574
Pubmed	Human skeletal muscle-specific alpha-actinin-2 and -3 isoforms form homodimers and heterodimers in vitro and in vivo.	ACTN2 ACTN3	1.05e-05	2	113	2	9675099
Pubmed	Human tankyrases are aberrantly expressed in colon tumors and contain multiple epitopes that induce humoral and cellular immune responses in cancer patients.	TNKS TNKS2	1.05e-05	2	113	2	18026951
Pubmed	Structural insights into SAM domain-mediated tankyrase oligomerization.	TNKS TNKS2	1.05e-05	2	113	2	27328430
Pubmed	Discovery of tankyrase inhibiting flavones with increased potency and isoenzyme selectivity.	TNKS TNKS2	1.05e-05	2	113	2	24116873
Pubmed	[Clinical characteristics and genetic analysis of hereditary spherocytosis caused by mutations of ANK1 and SPTB genes].	ANK1 SPTB	1.05e-05	2	113	2	31014431
Pubmed	Structures of the murine genes for the beta1- and beta4-subunits of the voltage-dependent calcium channel.	CACNB1 CACNB4	1.05e-05	2	113	2	14500989
Pubmed	Identification of two hERR2-related novel nuclear receptors utilizing bioinformatics and inverse PCR.	ESRRB ESRRG	1.05e-05	2	113	2	10072763
Pubmed	Inhibition of Epstein-Barr virus OriP function by tankyrase, a telomere-associated poly-ADP ribose polymerase that binds and modifies EBNA1.	TNKS TNKS2	1.05e-05	2	113	2	15795250
Pubmed	An ERRbeta/gamma agonist modulates GRalpha expression, and glucocorticoid responsive gene expression in skeletal muscle cells.	ESRRB ESRRG	1.05e-05	2	113	2	19631715
Pubmed	Structural insight into an ankyrin-sensitive lipid-binding site of erythroid beta-spectrin.	ANK1 SPTB	1.05e-05	2	113	2	17520478
Pubmed	Whole proteome analysis of human tankyrase knockout cells reveals targets of tankyrase-mediated degradation.	TNKS TNKS2	1.05e-05	2	113	2	29263426
Pubmed	Tankyrases inhibit innate antiviral response by PARylating VISA/MAVS and priming it for RNF146-mediated ubiquitination and degradation.	IFIH1 TNKS TNKS2	1.18e-05	14	113	3	35733260
Pubmed	Identification and overlapping expression of multiple unconventional myosin genes in vertebrate cell types.	MYO1E MYO7A MYO9A	1.18e-05	14	113	3	8022818
Pubmed	Voltage-activated calcium channel expression profiles in mouse brain and cultured hippocampal neurons.	CACNB1 CACNB3 CACNB4	1.48e-05	15	113	3	20188150
Pubmed	Differential expression of the actin-binding proteins, alpha-actinin-2 and -3, in different species: implications for the evolution of functional redundancy.	ACTN2 ACTN3 MTR	1.48e-05	15	113	3	11440986
Pubmed	Differential neuronal targeting of a new and two known calcium channel β4 subunit splice variants correlates with their regulation of gene expression.	CACNB1 CACNB3 CACNB4	1.48e-05	15	113	3	24453333
Pubmed	Comprehensive analysis of keratin gene clusters in humans and rodents.	KRT81 KRT83 KRT86	1.81e-05	16	113	3	15085952
Pubmed	Macrophage activation through CCR5- and CXCR4-mediated gp120-elicited signaling pathways.	PIK3C2A PIK3CG MAPK9	2.20e-05	17	113	3	12960231
Pubmed	The CCND1 c.870G>A polymorphism is a risk factor for t(11;14)(q13;q32) multiple myeloma.	TNKS POLQ DNAH11	2.20e-05	17	113	3	23502783
Pubmed	TIF1γ inhibits lung adenocarcinoma EMT and metastasis by interacting with the TAF15/TBP complex.	COL6A3 NASP MCM7 JUP GANAB HDLBP	2.74e-05	179	113	6	36261009
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	RAN CENPF KRT86 NUP98 MCM7 CHD3 KIF7 FAM83B RPL10A JUP GANAB TMED9 HDLBP	2.94e-05	1024	113	13	24711643
Pubmed	PERP regulates enamel formation via effects on cell-cell adhesion and gene expression.	KRT81 KRT83 KRT86	3.12e-05	19	113	3	21285247
Pubmed	Developmentally Programmed Tankyrase Activity Upregulates β-Catenin and Licenses Progression of Embryonic Genome Activation.	TNKS TNKS2	3.13e-05	3	113	2	32442396
Pubmed	Alternative splicing of the voltage-gated Ca2+ channel beta4 subunit creates a uniquely folded N-terminal protein binding domain with cell-specific expression in the cerebellar cortex.	CACNB3 CACNB4	3.13e-05	3	113	2	16525042
Pubmed	Estrogen-Related Receptors Mediate the Adaptive Response of Brown Adipose Tissue to Adrenergic Stimulation.	ESRRB ESRRG	3.13e-05	3	113	2	29888756
Pubmed	The human non-muscle alpha-actinin protein encoded by the ACTN4 gene suppresses tumorigenicity of human neuroblastoma cells.	ACTN2 ACTN3	3.13e-05	3	113	2	10656685
Pubmed	Cenp-F links kinetochores to Ndel1/Nde1/Lis1/dynein microtubule motor complexes.	CENPF NDEL1	3.13e-05	3	113	2	17600710
Pubmed	The association between the IFIH1 locus and type 1 diabetes.	IFIH1 FAP	3.13e-05	3	113	2	18071670
Pubmed	Role for the related poly(ADP-Ribose) polymerases tankyrase 1 and 2 at human telomeres.	TNKS TNKS2	3.13e-05	3	113	2	11739745
Pubmed	Expression and functional study of estrogen receptor-related receptors in human prostatic cells and tissues.	ESRRB ESRRG	3.13e-05	3	113	2	15598686
Pubmed	Disruption of Wnt/β-Catenin Signaling and Telomeric Shortening Are Inextricable Consequences of Tankyrase Inhibition in Human Cells.	TNKS TNKS2	3.13e-05	3	113	2	25939383
Pubmed	Arpin Regulates Migration Persistence by Interacting with Both Tankyrases and the Arp2/3 Complex.	TNKS TNKS2	3.13e-05	3	113	2	33923443
Pubmed	TANK2, a new TRF1-associated poly(ADP-ribose) polymerase, causes rapid induction of cell death upon overexpression.	TNKS TNKS2	3.13e-05	3	113	2	11454873
Pubmed	Factor-inhibiting hypoxia-inducible factor (FIH) catalyses the post-translational hydroxylation of histidinyl residues within ankyrin repeat domains.	TNKS TNKS2	3.13e-05	3	113	2	21251231
Pubmed	Mice with cardiac-specific sequestration of the beta-subunit of the L-type calcium channel.	CACNB1 CACNB3	3.13e-05	3	113	2	12054671
Pubmed	Spectrin's E2/E3 ubiquitin conjugating/ligating activity is diminished in sickle cells.	ANK1 SPTB	3.13e-05	3	113	2	15929114
Pubmed	Changing patterns in cytoskeletal mRNA expression and protein synthesis during murine erythropoiesis in vivo.	ANK1 SPTB	3.13e-05	3	113	2	1385865
Pubmed	Tankyrase inhibitors attenuate WNT/β-catenin signaling and inhibit growth of hepatocellular carcinoma cells.	TNKS TNKS2	3.13e-05	3	113	2	26246473
Pubmed	Inherited hemolytic disease in mice: a review and update.	ANK1 SPTB	3.13e-05	3	113	2	6763106
Pubmed	Sequence data and chromosomal localization of human type I and type II hair keratin genes.	KRT81 KRT86	3.13e-05	3	113	2	7556444
Pubmed	Mapping the binding sites of human erythrocyte ankyrin for the anion exchanger and spectrin.	ANK1 SPTB	3.13e-05	3	113	2	2141335
Pubmed	A clinical and experimental study of adult hereditary spherocytosis in the Chinese population.	ANK1 SPTB	3.13e-05	3	113	2	32133777
Pubmed	Class II phosphoinositide 3-kinases contribute to endothelial cells morphogenesis.	PIK3C2A PIK3CG	3.13e-05	3	113	2	23320105
Pubmed	Dissecting the molecular determinants of clinical PARP1 inhibitor selectivity for tankyrase1.	TNKS TNKS2	3.13e-05	3	113	2	33361107
Pubmed	Sequences and differential expression of three novel human type-II hair keratins.	KRT83 KRT86	3.13e-05	3	113	2	9084137
Pubmed	Tankyrase inhibition aggravates kidney injury in the absence of CD2AP.	TNKS TNKS2	3.13e-05	3	113	2	27441654
Pubmed	Structural basis of the alpha1-beta subunit interaction of voltage-gated Ca2+ channels.	CACNB3 CACNB4	3.13e-05	3	113	2	15170217
Pubmed	Dynamic expression of Lgr6 in the developing and mature mouse cochlea.	MYO7A LGR6	3.13e-05	3	113	2	26029045
Pubmed	Activation of human neutrophils induces an interaction between the integrin beta 2-subunit (CD18) and the actin binding protein alpha-actinin.	ACTN2 ACTN3	3.13e-05	3	113	2	8104223
Pubmed	ALL-1 is a histone methyltransferase that assembles a supercomplex of proteins involved in transcriptional regulation.	RAN CHD3 SIN3A	4.26e-05	21	113	3	12453419
Pubmed	HENA, heterogeneous network-based data set for Alzheimer's disease.	CENPF ACTN2 NDEL1 TNKS TNKS2	4.69e-05	120	113	5	31413325
Pubmed	An interactome perturbation framework prioritizes damaging missense mutations for developmental disorders.	CCDC14 FNDC3B KRT81 KRT83 FSD2 ACTN3 AP2S1 NDEL1 MAPK9	4.81e-05	514	113	9	29892012
Pubmed	DISC1 (Disrupted-In-Schizophrenia 1) is a centrosome-associated protein that interacts with MAP1A, MIPT3, ATF4/5 and NUDEL: regulation and loss of interaction with mutation.	ACTN2 CCDC141 NDEL1	4.92e-05	22	113	3	12812986
Pubmed	The light peak of the electroretinogram is dependent on voltage-gated calcium channels and antagonized by bestrophin (best-1).	CACNB1 CACNB4	6.25e-05	4	113	2	16636205
Pubmed	PARP5A and RNF146 phase separation restrains RIPK1-dependent necroptosis.	TNKS TNKS2	6.25e-05	4	113	2	38272024
Pubmed	Calmodulin-dependent gating of Ca(v)1.2 calcium channels in the absence of Ca(v)beta subunits.	CACNB1 CACNB3	6.25e-05	4	113	2	18535142
Cytoband	12q13	CACNB3 KRT81 KRT83 KRT86	2.98e-05	71	113	4	12q13
Cytoband	11q22	BIRC3 MTMR2	3.26e-04	11	113	2	11q22
GeneFamily	Actinins	ACTN2 ACTN3	1.24e-04	4	83	2	1112
GeneFamily	Calcium voltage-gated channel subunits	CACNB1 CACNB3 CACNB4	2.25e-04	26	83	3	253
GeneFamily	Calcium voltage-gated channel subunits\|Membrane associated guanylate kinases	CACNB1 CACNB3 CACNB4	2.25e-04	26	83	3	904
GeneFamily	Keratins, type II	KRT81 KRT83 KRT86	2.52e-04	27	83	3	609
GeneFamily	Phosphatidylinositol 3-kinase subunits	PIK3C2A PIK3CG	5.73e-04	8	83	2	831
GeneFamily	Laminin subunits	LAMB4 LAMA1	1.33e-03	12	83	2	626
GeneFamily	Zinc fingers\|Zinc fingers PARP-type\|Poly(ADP-ribose) polymerases	TNKS TNKS2	2.71e-03	17	83	2	684
GeneFamily	Ankyrin repeat domain containing	ANK1 IBTK ASAP2 TNKS TNKS2	5.13e-03	242	83	5	403
CoexpressionAtlas	skeletal muscle	CACNB1 CLTCL1 ANK1 SPTB ESRRB STYXL2 FSD2 PFKFB1 ACTN2 ACTN3 HOXC9	1.04e-06	320	112	11	skeletal muscle
CoexpressionAtlas	DevelopingKidney_e15.5_Cap mesenchyme_emap-27738_k-means-cluster#5_top-relative-expression-ranked_1000	NASP EFCAB14 IBTK PIK3C2A ATP11C TNKS TNKS2	1.25e-05	146	112	7	gudmap_developingKidney_e15.5_Cap mesenchyme_1000_k5
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k-means-cluster#3_top-relative-expression-ranked_1000	NASP IBTK PTPRG PIK3C2A ATP11C TNKS TNKS2 MAPK9 DNMBP FBXW11	2.61e-05	369	112	10	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k3_1000
CoexpressionAtlas	DevelopingKidney_e15.5_Medullary collecting duct_emap-28063_k-means-cluster#4_top-relative-expression-ranked_1000	ARHGEF28 CCDC141 CCNT2 IBTK PIK3C2A TNKS2 DNMBP HDLBP	7.40e-05	261	112	8	gudmap_developingKidney_e15.5_Medullary collecting duct_1000_k4
ToppCell	facs-Heart-LA-24m-Mesenchymal-ventricular_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK1 SPTB ESRRB FSD2 ACTN2 CCDC141 LGR6 RNF207	2.42e-08	186	112	8	337f768cc43db2db96ba6495b076006b1a5b0331
ToppCell	facs-Heart-LA-24m-Mesenchymal-ventricular_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK1 SPTB ESRRB FSD2 ACTN2 CCDC141 LGR6 RNF207	2.42e-08	186	112	8	e378c82ef6d6cb24751515aa499a01372b3e7ccf
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ARHGEF28 SPEF2 FAP NECAB1 PIK3CG RTN4RL2 PRLR	2.95e-07	174	112	7	bc978a2148a0261a4f9d1ca5479b707e224566be
ToppCell	droplet-Marrow-nan-24m-Lymphocytic-late_pro-B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DENND5B LARGE2 TMPRSS6 POU2AF1 SEMA6D RHPN2 PRLR	2.95e-07	174	112	7	cdfc50e5383c8670ce5109736aff36406f46c03d
ToppCell	droplet-Thymus-nan-18m-Myeloid-Plasma_cells_and_B_cells\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DENND5B LARGE2 FNDC3B TMPRSS6 SEMA6D RHPN2 PRLR	4.15e-07	183	112	7	ffb1bbbccb34d1a7e99872611f497450039d5019
ToppCell	10x5'-Liver-Lymphocytic_B-Naive_B_cells\|Liver / Manually curated celltypes from each tissue	DENND5B LARGE2 MYO1E POU2AF1 BIRC3 JUP STEAP1B	4.63e-07	186	112	7	23efdcedbe67f5e6c59106e052f570cd0338f1c1
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CACNB4 ESRRB ESRRG LAMA1 GSAP FAM83B SEMA6D	4.80e-07	187	112	7	b93cf4dfe8ffb89348ee7bccc9f284189f7240a2
ToppCell	facs-Heart-Unknown-3m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK1 SPTB ESRRB FSD2 ACTN2 CCDC141 RNF207	4.80e-07	187	112	7	0ffb988e0da2c7205c3515eca8e9851739bff5c5
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	LAMB4 CACNB4 ESRRB ESRRG FAM83B MEST SEMA6D	4.80e-07	187	112	7	77886f99c229610abd28c4c370d2c7d1536c9782
ToppCell	facs-Heart-Unknown\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK1 SPTB ESRRB FSD2 ACTN2 CCDC141 RNF207	4.80e-07	187	112	7	362e56426a568423a81e8a30e3ecf99b76135843
ToppCell	facs-Heart-Unknown-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK1 SPTB ESRRB FSD2 ACTN2 CCDC141 RNF207	4.80e-07	187	112	7	c004567767b89f3d89f5c7b28d952f3445957e1e
ToppCell	facs-Heart-Unknown-3m-Mesenchymal-ventricular_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK1 SPTB ESRRB FSD2 ACTN2 CCDC141 RNF207	4.98e-07	188	112	7	4db566f3f708e66730aa9e16f4d73d91dc534177
ToppCell	facs-Heart-Unknown-3m-Mesenchymal-ventricular_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK1 SPTB ESRRB FSD2 ACTN2 CCDC141 RNF207	4.98e-07	188	112	7	6704b92991ad8c0a910e9f36cd33d00bd26dcb8f
ToppCell	facs-Heart-RA-24m-Mesenchymal-ventricular_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK1 ESRRG FSD2 ACTN2 CCDC141 LGR6 RNF207	5.16e-07	189	112	7	e758b264c0a47127e33e66c395cf5a3224c7305b
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FNDC3B CACNB4 ESRRB ESRRG LAMA1 ASAP2 SEMA6D	5.16e-07	189	112	7	975c0f079903ae36b0ffa54e86294d42ec7697de
ToppCell	facs-Brain_Non-Myeloid-Striatum_-18m-Epithelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LARGE2 CACNB3 TMPRSS6 BIRC3 FAM83B HOXC9 PRLR	5.16e-07	189	112	7	6f0fc5271a7d3682f145e734abc3be6473dda2e2
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FNDC3B CACNB4 ESRRB ESRRG LAMA1 ASAP2 SEMA6D	5.16e-07	189	112	7	7eb8f5a951e80f1cfac4d7c9eb169f4eb100c917
ToppCell	facs-Heart-RA-24m-Mesenchymal-ventricular_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK1 ESRRG FSD2 ACTN2 CCDC141 LGR6 RNF207	5.16e-07	189	112	7	b98f60875b1a12b2ec9dc91889298ae57f98602f
ToppCell	facs-Brain_Non-Myeloid-Striatum_-18m-Epithelial-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LARGE2 CACNB3 TMPRSS6 BIRC3 FAM83B HOXC9 PRLR	5.16e-07	189	112	7	3b9ce8964b16cb2200d30cbb0bfc711dcad2380e
ToppCell	facs-Brain_Non-Myeloid-Striatum_-18m-Epithelial-neuroepithelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LARGE2 CACNB3 TMPRSS6 BIRC3 FAM83B HOXC9 PRLR	5.16e-07	189	112	7	38acb307907fde68b992057714448c1561d69ee3
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FNDC3B MYO9A ESRRB ESRRG LAMA1 FAM83B PTPRG	5.34e-07	190	112	7	bf4511395fa97efd1c1cd17cc9bebb0271ee7f0e
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FNDC3B MYO9A ESRRB ESRRG LAMA1 FAM83B PTPRG	5.34e-07	190	112	7	b6b8964b4910083499681b5fdf554e127b6a4c4e
ToppCell	facs-Heart-LV-24m-Mesenchymal-ventricular_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK1 CENPF SPTB ESRRB FSD2 ACTN2 RNF207	5.54e-07	191	112	7	543da1197c7e62f2c9cbd4a51414bbaaa6d1a92f
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FNDC3B MYO9A ESRRB ESRRG LAMA1 FAM83B PTPRG	5.54e-07	191	112	7	2fa1b9e76a0ed2d2f0de74349e266cf4a5f51aad
ToppCell	facs-Heart-LV-24m-Mesenchymal-ventricular_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK1 CENPF SPTB ESRRB FSD2 ACTN2 RNF207	5.54e-07	191	112	7	9d7d680da3979e256191b534ebd14c5383e0cf93
ToppCell	droplet-Heart-nan-3m-Mesenchymal-atrial_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK1 SPTB ESRRB FSD2 ACTN2 CCDC141 RNF207	5.54e-07	191	112	7	97fb4232417a39801e87725755fd16a57c250209
ToppCell	droplet-Heart-nan-3m-Mesenchymal-cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK1 SPTB ESRRB FSD2 ACTN2 CCDC141 RNF207	5.54e-07	191	112	7	64070a309d7e3f6001272409ab9ce206d0e7d73f
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	GPLD1 CACNB4 ST7 CCDC141 UBTD1 PTPRG NECAB1	6.15e-07	194	112	7	97534c8bba895a7913665e03ae4e5c4a6ad71daf
ToppCell	Substantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1-Endothelial_Tip.Dcn.Alcam_(Alcam)\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	CCDC14 COL6A3 SPTLC1 BIRC3 KIF7 CHTF18	1.62e-06	142	112	6	6a656d28c9f5dfb03a3a2d908cf2edbe0a5b1206
ToppCell	Substantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	CCDC14 COL6A3 SPTLC1 BIRC3 KIF7 CHTF18	1.62e-06	142	112	6	671ba8869db7a6dc69fd1caf0e561f15a312b170
ToppCell	Substantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_2\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	CCDC14 COL6A3 SPTLC1 BIRC3 KIF7 CHTF18	1.62e-06	142	112	6	3557084150670fd2e2634fc674f228ab85181b59
ToppCell	Substantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1-Endothelial_Tip.Dcn.Alcam_(Alcam)-\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	CCDC14 COL6A3 SPTLC1 BIRC3 KIF7 CHTF18	1.62e-06	142	112	6	a3d1f4b570b75402171e38c5a7c88e2896520c8f
ToppCell	droplet-Lung-nan-3m-Lymphocytic-Proliferating_NK\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCDC14 CENPF ULK3 DBF4 CHTF18 MTBP	3.00e-06	158	112	6	ee8ce3cd202807df692b28bb1a81827d49d73862
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A3 CENPF CHD3 FAP CHTF18 POLQ	3.35e-06	161	112	6	a7e09cf2ca6cd70d40d08440fe9c5ab9befa1b79
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A3 CENPF CHD3 FAP CHTF18 POLQ	3.35e-06	161	112	6	08920a716f6ec62538e361211455a30ad726d7be
ToppCell	ICU-SEP-Lymphocyte-B-B_intermediate\|ICU-SEP / Disease, Lineage and Cell Type	DENND5B POU2AF1 BIRC3 CCDC141 HTR3B STEAP1B	4.73e-06	171	112	6	2e44bf6f3d90193e7cadcac48bb852bd632a81bc
ToppCell	facs-Heart-Unknown-3m-Mesenchymal-atrial_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK1 SPTB FSD2 ACTN2 CCDC141 RNF207	4.89e-06	172	112	6	ee8ce9e8c9a6d3ee2be113f77743958005f4b3f0
ToppCell	facs-Heart-Unknown-3m-Mesenchymal-atrial_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK1 SPTB FSD2 ACTN2 CCDC141 RNF207	4.89e-06	172	112	6	bd468a7ea6ec832dcf6a816a1e0c03fa0f176dad
ToppCell	systemic_lupus_erythematosus-managed-Lymphocytic_B-plasmablast-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	DENND5B GPLD1 MYO1E CENPF POU2AF1 POLQ	5.40e-06	175	112	6	89bf89466191da14896ed8928027f5b911436c22
ToppCell	390C-Lymphocytic-CD4_T-cell-Proliferating_T_cell\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	ANK1 MYO1E SPTB MCM7 ASAP2 PTPRG	5.58e-06	176	112	6	941e8724b6f680719ef2a4f190f943b205bb9e78
ToppCell	droplet-Limb_Muscle-nan-18m-Mesenchymal-skeletal_muscle_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNB1 ANK1 FSD2 PFKFB1 ACTN2 ACTN3	5.77e-06	177	112	6	f6ff1b035fa2418f2448c99d81faa927ece93dfa
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ARHGEF28 ACTN2 NECAB1 PIK3CG RTN4RL2 PRLR	6.15e-06	179	112	6	1ac79c82c52fa95bb4e170ab20fec0f648db2134
ToppCell	FF-Differ-KC\|World / shred by cell class for mouse tongue	KRT81 KRT83 KRT86 FSD2 FIBCD1 DNAH11	6.15e-06	179	112	6	1526a130565a97c291a25a7a988089bffc1515c1
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CACNB4 ESRRB ESRRG LAMA1 SEMA6D PROM2	6.35e-06	180	112	6	eee71184ebed2694d3e60f579a44b3cf7dd2cd35
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CACNB4 ESRRB ESRRG LAMA1 SEMA6D PROM2	6.35e-06	180	112	6	a17dbe03597b81e7a1fe2bf2d23e59e55c615a2a
ToppCell	droplet-Marrow-nan-21m-Lymphocytic-late_pro-B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DENND5B FNDC3B TMPRSS6 POU2AF1 SEMA6D PRLR	6.56e-06	181	112	6	97022416d0f5a5ba9c9bd5e70ce95cf4cb19af89
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	LAMB4 ESRRB ESRRG FAM83B MEST SEMA6D	6.77e-06	182	112	6	a8cc56f32efe180e8fb5d69dbe606a794b3db700
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CACNB4 ESRRB ESRRG PFKFB1 ASAP2 SEMA6D	6.77e-06	182	112	6	5f513bbb7125956eb528e3120de3fd776770a7c3
ToppCell	droplet-Limb_Muscle-nan-3m-Mesenchymal-skeletal_muscle_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNB1 ANK1 ESRRG FSD2 ACTN2 ACTN3	6.77e-06	182	112	6	edfc598b7199ca1d8a399b264ab863c299b1eede
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CACNB4 ESRRB ESRRG LAMA1 FAM83B SEMA6D	6.77e-06	182	112	6	041bc819e6cf2618bf86bce8dfe2df673f392ba3
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CACNB4 ESRRB ESRRG LAMA1 FAM83B SEMA6D	6.98e-06	183	112	6	31ab55d5f3639f5964541d5eae23044dbda3356e
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CACNB4 ESRRB ESRRG PFKFB1 ASAP2 SEMA6D	6.98e-06	183	112	6	2e831a4d99c6f983793df71c0994124c943c6da9
ToppCell	droplet-Marrow-nan-3m-Lymphocytic-late_pro-B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DENND5B TMPRSS6 POU2AF1 SEMA6D PRLR HDLBP	7.20e-06	184	112	6	42cadfdb5d29a50bd7e901ddd14d42b39e8474f0
ToppCell	3'-Child04-06-SmallIntestine-Hematopoietic-Plasma_cells-IgA_plasma_cell\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GPLD1 FNDC3B CENPF POU2AF1 PIK3CG TMED9	7.43e-06	185	112	6	ff598af88c7f9d7224cc4ed96b1c3463ef76b550
ToppCell	10x3'2.3-week_14-16-Myeloid_macrophage-stroma-osteoclast\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	MYO1E SLC39A1 BIRC3 ACTN2 FIBCD1 RNF207	7.43e-06	185	112	6	5ed49b6d8214c6119355a6d3ee4e25d40bcc0c53
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CACNB4 ESRRB ESRRG LAMA1 FAM83B SEMA6D	7.43e-06	185	112	6	898a093757f86be3e18d2ef1f16a71f50ef81dc3
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CACNB4 ESRRB ESRRG LAMA1 SEMA6D PROM2	7.90e-06	187	112	6	85e58a312fc325e4063a2d250666b99b8f99beb6
ToppCell	facs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l20-23\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ANK1 GSAP ACTN3 MEST MTR RTN4RL2	7.90e-06	187	112	6	69b47f00598d647e2a99427ebddf42c339428e47
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ARHGEF28 MYO9A KRT81 TSPEAR GSAP RNF207	7.90e-06	187	112	6	58d48128547ee3513d0bf7f78e61b76b1c472ca9
ToppCell	facs-Heart-LA/RA-3m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK1 SPTB FSD2 ACTN2 CCDC141 RNF207	8.14e-06	188	112	6	90dc0e15798d0b984518ad58c7e416e30aff687a
ToppCell	facs-Heart-LA/RA-3m-Mesenchymal-atrial_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK1 SPTB FSD2 ACTN2 CCDC141 RNF207	8.14e-06	188	112	6	f63dfd076ced81013918363282ae25cbbd8948ae
ToppCell	facs-Heart-LA/RA-3m-Mesenchymal-atrial_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK1 SPTB FSD2 ACTN2 CCDC141 RNF207	8.14e-06	188	112	6	0554d542149cef654ff1e5e32dfbffd8990b52bd
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LAMB4 CACNB4 ESRRB ESRRG LAMA1 SEMA6D	8.39e-06	189	112	6	f51cdc9a47371cab8ed9ae63a6f14da07ede446c
ToppCell	facs-Heart-LA/RA-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK1 SPTB FSD2 ACTN2 CCDC141 RNF207	8.39e-06	189	112	6	a08b2d0fa35ffa510050ecffdc68e1b79bbe1632
ToppCell	renal_medulla_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	MYO9A ESRRB ESRRG LAMA1 SEMA6D STEAP1B	8.39e-06	189	112	6	830d9cd0dd706bce22eb2416f07b2c31c870a05a
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CACNB4 ESRRB ESRRG LAMA1 RPL10A SEMA6D	8.39e-06	189	112	6	55420853f730b433ef58ac9337ac84ac78a247a0
ToppCell	facs-Heart-LA/RA\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK1 SPTB FSD2 ACTN2 CCDC141 RNF207	8.39e-06	189	112	6	efa913d9c16fc32166b484d92b6449e8a0c59e03
ToppCell	NS-critical-d_07-13-Epithelial-FOXN4+\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CCDC14 CENPF ST7 MCM7 ASAP2 FIBCD1	8.65e-06	190	112	6	7be0f2ff86ca8500a43e0d44e5e292530f9ba0bb
ToppCell	NS-moderate-d_16-33-Epithelial-FOXN4+\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CCDC14 CENPF ST7 MCM7 ASAP2 FIBCD1	8.65e-06	190	112	6	250ca4a605c1cccd77d23383e4fe6f91cf3609ba
ToppCell	droplet-Heart-nan-18m-Mesenchymal-cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK1 SPTB FSD2 ACTN2 LGR6 RNF207	9.18e-06	192	112	6	0bf99e029a06151092db1e8a0dcb45f4e688e771
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CCDC14 CACNB1 CACNB4 CCDC141 PTPRG NECAB1	9.18e-06	192	112	6	cc9911e182a289779a2612bc213daae5607689e7
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CACNB4 MYO9A ESRRB ESRRG LAMA1 SEMA6D	9.18e-06	192	112	6	ee27d27e3d269764dbe8711d0b37ff9331a298a9
ToppCell	droplet-Heart-nan-18m-Mesenchymal-atrial_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK1 SPTB FSD2 ACTN2 LGR6 RNF207	9.18e-06	192	112	6	d766221acfce30cbf2c60b3ae40f6744968b952c
ToppCell	P07-Endothelial-proliferative_endothelial_cell\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	RAN CENPF NASP MCM7 MEST DBF4	9.46e-06	193	112	6	1e95ef29357969ee385b4717c0b5a497390ac260
ToppCell	10x5'v1-week_17-19-Mesenchymal_osteo-stroma-early_osteoblast\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	COL6A3 FAP HOXC9 SEMA6D PTPRG ASCL1	9.46e-06	193	112	6	5e46a9f65e85aca78f825fdef88a95b97eec8743
ToppCell	PSB-critical-LOC-Epithelial-FOXN4+\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CCDC14 CENPF ST7 MCM7 ASAP2 DBF4	9.46e-06	193	112	6	b7d9c5bed524423e92f01496a9f8fad11b33a3f7
ToppCell	P07-Endothelial-proliferative_endothelial_cell-proliferative_endothelial_cell\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	RAN CENPF NASP MCM7 MEST DBF4	9.46e-06	193	112	6	0f21fb8b35f89f4c1c8109d1a4d3d08a452f9edd
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CACNB4 MYO1E ESRRG FAM83B JUP ASAP2	9.74e-06	194	112	6	46070fbb0ee0eb9e1801c43b73a15707471056dc
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CACNB4 MYO1E ESRRG FAM83B JUP ASAP2	9.74e-06	194	112	6	abacb6a8d7a9003f2f6c2be0305507f1c1c50347
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_B_plasma-Plasmablasts\|lymph-node_spleen / Manually curated celltypes from each tissue	FNDC3B CENPF POU2AF1 TMED9 POLQ HDLBP	1.00e-05	195	112	6	1390728b9a514db534e8bc6dcf72cf51a1065780
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ARHGEF28 MYO9A ESRRB ESRRG LAMA1 MTR	1.03e-05	196	112	6	eea66711a16134f86e6c533a5a837ff2e0d7ca7f
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CACNB4 ESRRB ESRRG MEST SEMA6D PROM2	1.09e-05	198	112	6	688b0eb5534dde40b8630ab8a3252c816711e02e
ToppCell	wk_15-18-Mesenchymal-Fibroblast-Early_fibro\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	RAN CENPF NASP MCM7 RPL10A MEST	1.09e-05	198	112	6	ecf0a8f2e07f336e23b6f32a2c48d3c7eb66572b
ToppCell	PBMC-Severe-Lymphocyte-B-Plasmablast-Plasmablast-Developping_Plasmablast\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	DENND5B CENPF POU2AF1 MCM7 POLQ HDLBP	1.09e-05	198	112	6	2d8d4eb21b4fe3cc178b3518b3ea39c2d9650f24
ToppCell	10x3'2.3-week_12-13-Lymphocytic_B-B_lineage-pre_pro_B_progenitor\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	RAN CENPF NASP POU2AF1 MCM7 JUP	1.13e-05	199	112	6	8e7f9312dec1e3a92b6a0ccc7baa2d46e89c11f3
ToppCell	Tracheal-NucSeq\|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations	USP34 FNDC3B ARHGEF28 PTBP2 ESRRG TNKS	1.13e-05	199	112	6	94b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCell	5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CCDC14 CACNB4 MYO9A CCDC141 PTPRG NECAB1	1.13e-05	199	112	6	2dc33804f6691d7c9682e6c9b885e945fb97fc36
ToppCell	Parenchymal-10x3prime_v2-Epithelial-Epi_airway_basal-Dividing_Basal\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	CACNB4 CENPF CHTF18 FIBCD1 POLQ RTN4RL2	1.13e-05	199	112	6	f0c289523957258d16135c04679db379d43d28d9
ToppCell	Transverse-(2)_B_cell-(24)_B_cell_cycling\|Transverse / shred on region, Cell_type, and subtype	CCDC14 GPLD1 MYO1E ESRRG POLQ DNMBP	1.16e-05	200	112	6	e3f9736227151f23f0e331eec0a7a15ce464b517
ToppCell	Transverse-B_cell-B_cell_cycling\|Transverse / Region, Cell class and subclass	CCDC14 GPLD1 MYO1E ESRRG POLQ DNMBP	1.16e-05	200	112	6	0e270f8019d9f22068ca426d661937262a5cd331
ToppCell	critical-Epithelial-FOXN4+\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	CCDC14 CENPF ST7 MCM7 ASAP2 DBF4	1.16e-05	200	112	6	f39db4250ce220a3eb58edee3f7fc3671701d46f
ToppCell	COVID-19-Heart-CM_5_(RYR2-)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CACNB1 CLTCL1 SPTB FSD2 ACTN3	3.19e-05	144	112	5	f92e03dd784e31a9e5dbd4f4c3a6517ea19210cf
ToppCell	367C-Lymphocytic-NK_cells-NK_cell_D2\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	ARHGEF28 KRT81 TMPRSS6 KRT86 ACTN3	4.00e-05	151	112	5	09405a450af3ea246d9685a6d3137dfaec80e9bf
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ESRRB ESRRG LAMA1 SEMA6D PROM2	4.26e-05	153	112	5	0307f10e772021ae68a42690634df458672a6df9
ToppCell	367C-Lymphocytic-CD4_T-cell-Treg_cell_2\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	MYO1E BIRC3 CCDC141 PROM2 TNKS	4.40e-05	154	112	5	9200e2f1783e54cbc5dfc3b485b57c761af74a46
ToppCell	COVID-19-Heart-CM_5_(RYR2-)\|Heart / Disease (COVID-19 only), tissue and cell type	CACNB1 CLTCL1 SPTB PFKFB1 ACTN3	4.53e-05	155	112	5	d7e26696fd9c0a759524f331243db43059b33ed9
ToppCell	367C-Lymphocytic-NK_cells-NK_cell_C\|367C / Donor, Lineage, Cell class and subclass (all cells)	KRT81 KRT86 GSAP GPATCH8 NME8	4.68e-05	156	112	5	a1b9e7621b646d354c2ccd850ce6a4fa9ff8a026
ToppCell	droplet-Kidney-KIDNEY-30m-Lymphocytic-Epcam____proximal_tube_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NASP POU2AF1 CHTF18 MTR KIF13A	4.97e-05	158	112	5	1d78578dc1f8ba43dacdccae1082c0b9d749f64d
ToppCell	3'-Pediatric_IBD-SmallIntestine-Hematopoietic-T_cells-ILC3\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MYO7A KRT81 KRT86 BIRC3 RNF207	5.43e-05	161	112	5	584e44e6048c2678eb72cd23a86f48f2466c5da4
ToppCell	PND01-03-samps\|World / Age Group, Lineage, Cell class and subclass	DENND5B SLC39A1 TEX11 JUP TRPM1	5.43e-05	161	112	5	1973b112d8d67aacc02751797d0148e7b53bfa66
Drug	Morantel tartrate [26155-31-7]; Down 200; 10.8uM; PC3; HT_HG-U133A	DENND5B USP34 CACNB3 MYO1E CHD3 GSAP IFIH1 TNKS EPHA1	5.77e-07	197	112	9	1798_DN
Drug	Nimodipine	CACNB1 CACNB3 CACNB4	9.53e-06	9	112	3	DB00393
Drug	gluconate	CLTCL1 ESRRB ESRRG SPTLC1 GSAP PIK3C2A PIK3CG ABCD1 PRLR	1.25e-05	287	112	9	CID000000604
Drug	Mibefradil	CACNB1 CACNB3 CACNB4	1.86e-05	11	112	3	DB01388
Drug	melicopicine	KRT81 KRT83	2.40e-05	2	112	2	CID000101253
Drug	N'-((1E)-(4-(diethylamino)phenyl)methylene)-4-hydroxybenzohydrazide	ESRRB ESRRG	2.40e-05	2	112	2	ctd:C501618
Drug	tebuquine	KRT81 KRT83	2.40e-05	2	112	2	CID000071991
Drug	3,5-di-O-galloylquinic acid	KRT81 KRT83	2.40e-05	2	112	2	CID000460896
Disease	Beaded hair	KRT81 KRT83 KRT86	5.18e-08	3	111	3	cv:C0546966
Disease	MONILETHRIX	KRT81 KRT83 KRT86	5.18e-08	3	111	3	158000
Disease	monilethrix (is_implicated_in)	KRT81 KRT83 KRT86	5.18e-08	3	111	3	DOID:0050472 (is_implicated_in)
Disease	Monilethrix	KRT81 KRT83 KRT86	2.07e-07	4	111	3	C0546966
Disease	hair disease (is_implicated_in)	KRT81 KRT86	1.40e-05	2	111	2	DOID:421 (is_implicated_in)
Disease	Anemia, hereditary spherocytic hemolytic	ANK1 SPTB	1.39e-04	5	111	2	C0221409
Disease	hereditary spherocytosis (is_implicated_in)	ANK1 SPTB	1.39e-04	5	111	2	DOID:12971 (is_implicated_in)
Disease	Hereditary spherocytosis	ANK1 SPTB	1.39e-04	5	111	2	cv:C0037889
Disease	focal segmental glomerulosclerosis 1 (implicated_via_orthology)	ACTN2 ACTN3	1.39e-04	5	111	2	DOID:0111128 (implicated_via_orthology)
Disease	bilirubin measurement	ANK1 TMPRSS6 SPTB CHD3 LGR6 STEAP1B DNMBP DNAH11	2.74e-04	442	111	8	EFO_0004570
Disease	Primary ciliary dyskinesia	CENPF NME8 DNAH11	3.38e-04	36	111	3	cv:C0008780
Disease	AUTISM, SUSCEPTIBILITY TO, 15	SIN3A FBXW11	3.87e-04	8	111	2	C2677504
Disease	Hereditary spherocytosis	ANK1 SPTB	3.87e-04	8	111	2	C0037889
Disease	response to clopidogrel, response to acetylsalicylate, major adverse cardiovascular event measurement	TSPEAR NECAB1	4.96e-04	9	111	2	EFO_0020863, GO_1903492, GO_1903493
Disease	response to carboplatin, response to antineoplastic agent	SPEF2 ULK3	6.19e-04	10	111	2	GO_0097327, GO_0097328
Disease	creatinine measurement	DENND5B VIL1 CENPF NASP POU2AF1 FSD2 SIN3A TEX11 FAM83B ULK3 FAP	1.33e-03	995	111	11	EFO_0004518
Disease	Colorectal Carcinoma	CACNB1 LAMA1 TSPEAR HPS3 HOXC9 RHPN2 ATP11C LGR6 EPHA1	1.36e-03	702	111	9	C0009402
Disease	Ischemic stroke	COL6A3 CHD3 PTPRG RHPN2 HTR3B DNAH11	1.44e-03	324	111	6	HP_0002140
Disease	colorectal mucinous adenocarcinoma	CCDC141 TRPM1	1.63e-03	16	111	2	EFO_0009361
Disease	blood urea nitrogen measurement	VIL1 ESRRG FAM83B JUP PIK3CG LGR6 PRLR	1.64e-03	452	111	7	EFO_0004741
Disease	Mental Retardation, Psychosocial	LAMA1 SIN3A KIF7 ASCL1	1.91e-03	139	111	4	C0025363
Disease	Profound Mental Retardation	LAMA1 SIN3A KIF7 ASCL1	1.91e-03	139	111	4	C0020796
Disease	Mental deficiency	LAMA1 SIN3A KIF7 ASCL1	1.91e-03	139	111	4	C0917816
Disease	FEV/FEC ratio	USP34 FNDC3B COL6A3 ARHGEF28 SPEF2 ESRRG NASP MCM7 FAM83B ASAP2 KIF13A HDLBP	2.28e-03	1228	111	12	EFO_0004713
Disease	lung carcinoma	GPLD1 COL6A3 LAMA1 SEMA6D STEAP1B RTN4RL2 DNAH11	2.35e-03	482	111	7	EFO_0001071
Disease	Malignant neoplasm of breast	FNDC3B ANK1 CENPF TMPRSS6 SPTLC1 NUP98 NME8 ZNF644 MTR LGR6 HDLBP	2.43e-03	1074	111	11	C0006142
Disease	Bronchiectasis	NME8 DNAH11	3.08e-03	22	111	2	C0006267
Disease	Nonsyndromic Deafness	MYO7A ESRRB TSPEAR	3.57e-03	81	111	3	C3711374
Disease	Hodgkins lymphoma	ARHGEF28 POU2AF1 RTN4RL2	3.70e-03	82	111	3	EFO_0000183

Protein segments in the cluster

Peptide	Gene	Start	Entry
EEQYIFIHDALLEAI	PTPRG	1106	P23470
HDFILEATQDDYVLE	PTPRG	1296	P23470
EEAQAYLAAGQHDLV	BARGIN	646	Q6ZT62
HNQFAAELEVLAELE	CHTF18	16	Q8WVB6
EVNYQPLDEELDSHL	PFKFB1	201	P16118
GANLTYELHVLNQDE	EPHA1	476	P21709
ETLDLDVRDHYIAAQ	CCNT2	446	O60583
IAAIAQELNELDYHD	ACTN2	461	P35609
ENQLEDACEHLAEYL	CACNB1	391	Q02641
QLEDACEHLAEYLEV	CACNB3	341	P54284
LDLFVHAILDVDAEN	HTR3B	61	O95264
QYDAEIDDITLDHLT	ANK1	326	P16157
LHAALYNFDQDTLEI	DNAH11	4056	Q96DT5
RNSLQEAEAVLYEHL	BIRC3	511	Q13489
EAEAVLYEHLFVQQD	BIRC3	516	Q13489
QNHDEAIALLEIYEK	DNMBP	871	Q6XZF7
EIAAASYLQDDALHL	CCM2L	136	Q9NUG4
ENDLEELRVDHYKCN	DBF4	471	Q9UBU7
ENQLEDACEHLGEYL	CACNB4	381	O00305
ALIEDEHNLDNTIYI	CCDC14	766	Q49A88
DILYLHNSLEEVNSA	EFCAB14	266	O75071
VDVNDNNLAYLEAIH	AP2S1	71	P53680
YLQENSLLHLQDDLF	RTN4RL2	161	Q86UN3
PALAAQYEHDLEVAQ	RAN	191	P62826
VAHIVELDAQEYELL	LARGE2	641	Q8N3Y3
DLEANCLDDSIYQHL	RADIL	786	Q96JH8
YSEQDLEAILDVVHL	ABCD1	571	P33897
GELDLQLQEYQHSLE	ARHGEF28	1491	Q8N1W1
EDLNNYCAELIEHPL	GGT3P	251	A6NGU5
QIYDAQLEEREHAIE	MAPK9	336	P45984
YVDSLISHDNEDLLA	HOXC9	11	P31274
IRHLASDAIINENYD	NUP98	1651	P52948
ARQAENHYDQDLDEL	LGR6	516	Q9HBX8
IEEHAIQDLLVFYEA	IBTK	1311	Q9P2D0
LAHVENEEQYTQALE	ASAP2	66	O43150
LASELNHVQEVLEGY	KRT86	176	O43790
LEDLCFILQEEYHLN	DDX58	611	O95786
AIDILIEHGLEAYQE	FAM83B	31	Q5T0W9
QYEEGHLEIEQASLD	GPATCH8	21	Q9UKJ3
EELLDSYHNQVELAL	PIK3C2A	551	O00443
QGLDHIAENILSYLD	FBXW11	126	Q9UKB1
IDENDLLDCLVHVSY	KIF7	131	Q2M1P5
ILAVNNDVVEHEDYA	PDZD3	161	Q86UT5
DAYQNAELVFLDIHN	MTMR2	341	Q13614
AIVHLINYQDDAELA	JUP	126	P14923
LQEQYLEAHDRLLAE	NASP	571	P49321
AHREQVALYVDLDDV	MCM7	41	P33993
LLEEEDSDAYALNHT	POU2AF1	236	Q16633
ADVLENDYESLHVLN	GSAP	36	A4D1B5
AEVYEQLELHSLLDA	CEP104	281	O60308
QEATDLAQHLYGLEE	CCDC141	1071	Q6ZP82
HEALYLEADLEVVQT	CENPF	1916	P49454
YIRALQQLLDEHDAV	ASCL1	166	P50553
SVIHYDNEAIARLLD	CHD3	1251	Q12873
HAAEDIVYTLQLEDR	FNDC3B	986	Q53EP0
LQDVLHEALQDYEAG	ESRRG	391	P62508
LQLHDELLYEVAEED	POLQ	2536	O75417
LDLDYELAEQLDNIA	COL6A3	2011	P12111
SFENAHDEYLQLLNL	IFIH1	106	Q9BYX4
LHCEEAELRDYQLNV	DENND5B	486	Q6ZUT9
QAAYELHVDLEDFEN	FIBCD1	326	Q8N539
DLDEYQLHNCVEIAS	LAMB4	726	A4D0S4
LQDLLHEALQDYELS	ESRRB	366	O95718
INLLSHDYGDIVAQE	MEST	141	Q5EB52
LASELNHVQEVLEGY	KRT83	181	P78385
ADLYEEAAENLHQLS	MTBP	141	Q96DY7
LELNELGEYAAVELH	KIF13A	996	Q9H1H9
SDAIHNDLQDDSLYL	POLR1E	186	Q9GZS1
EQEIYEAQLHDLLQL	RNF207	506	Q6ZRF8
AHEAQEEAYREEQLI	SPEF2	321	Q9C093
VEEAIQALIDLHNYN	PTBP2	501	Q9UKA9
NHSLYENLDEELNEE	HPS3	611	Q969F9
NIDDQYLLGDALLVH	GANAB	741	Q14697
HYNIQSLIEESEELA	LAMA1	1906	P25391
DLQEEVDELVHLYGL	FSD2	66	A1L4K1
QDDIHLYAEAAVPQA	MTR	1041	Q99707
HLSLAYEDKQILEDA	SIN3A	776	Q96ST3
ENLLEALLELQAYAD	ST7	336	Q9NRC1
RLTYAQHQEEDDLLN	RHPN2	451	Q8IUC4
EHYGINIDDIDLISA	SPTLC1	291	O15269
NLEDNDYLQTAHADE	STEAP1B	21	Q6NZ63
EHIAALAQELNELDY	ACTN3	466	Q08043
LAQELNELDYHEAAS	ACTN3	471	Q08043
ALNHLLTEEEDYQGL	CLTCL1	1466	P53675
EIEEYELLHTLNFDA	ATP11C	531	Q8NB49
LEDDDVLHYLLQLVQ	PIK3CG	651	P48736
LDIQVGEHANDYAEI	TMED9	141	Q9BVK6
NVDYLLIHGTADDNV	FAP	691	Q12884
TQDLLSHEDCYILDQ	VIL1	276	P09327
EYLERQHLAQLCDIE	NME8	276	Q8N427
QLNDSYDLEEHLDIN	PROM2	561	Q8N271
DYLAAIDEALAALHV	SLC39A1	91	Q9NY26
EEDEANVRAVQAHYL	STYXL2	16	Q5VZP5
EVAEYLLEHGADVNA	TNKS	851	O95271
LVEYLEVDDSEDQHL	PRLR	311	P16471
ELLLEHQDAYQAGIV	GPLD1	51	P80108
ALEYLAQHSEDQEQV	TEX11	561	Q8IYF3
EDTIDQELEQLYLSH	PPP1R3F	481	Q6ZSY5
RLTYAQHQEDDDLLN	RHPN2P1	366	A8MT19
LEDLAQELEKENYHD	SPTB	481	P11277
YAAEANDHELAQAIL	UBTD1	76	Q9HAC8
AYEIHLEQQSEEELQ	RALGAPB	1071	Q86X10
DDELVYNIHLAVNFL	RPL10A	176	P62906
NLEVAEYLLQHGADV	TNKS2	691	Q9H2K2
LELLDQSYKHDEQIA	TRPM1	681	Q7Z4N2
DEDLESVDAFQHLIY	ZNF644	351	Q9H582
LAAKERLDYVEEHQN	TSPEAR	306	Q8WU66
LEEENSLAEYHSRLD	TRIP4	336	Q15650
AIDHILNLEEEYLAD	HDLBP	1186	Q00341
FNYILADHDDQDVVL	USP34	2831	Q70CQ2
NDSVLLEEIEAYNHA	SEMA6D	461	Q8NFY4
EEDSHDYDVALLQLD	TMPRSS6	661	Q8IU80
EQDALDLYQHSLGEL	ULK3	396	Q6PHR2
LASELNHVQEVLEGY	KRT81	176	Q14533
DDIFILHEQEYDSLL	MYO1E	831	Q12965
LLYHDDEGDQLAALA	MYO7A	1026	Q13402
DAESVNLDDYNIHVI	MYO9A	2116	B2RTY4
LHKYVRELEQANDDL	NDEL1	111	Q9GZM8
QHLGEYENVLAALED	NECAB1	91	Q8N987