Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionextracellular matrix structural constituent

RELN TECTA EFEMP1 LTBP2 BMPER FGG MUC2 MUC5AC

3.43e-051881318GO:0005201
GeneOntologyMolecularFunctionalpha-L-arabinofuranosidase activity

OTOGL OTOG

4.27e-0521312GO:0046556
GeneOntologyMolecularFunctiontransmembrane receptor protein kinase activity

ERBB4 ACVR1B ACVR2B EFEMP1 EPHA10

2.43e-04851315GO:0019199
GeneOntologyMolecularFunctionepidermal growth factor receptor activity

ERBB4 EFEMP1

2.54e-0441312GO:0005006
GeneOntologyMolecularFunctioninhibin binding

ACVR1B ACVR2B

4.22e-0451312GO:0034711
GeneOntologyMolecularFunctionthiol oxidase activity

ERO1B ERO1A

6.30e-0461312GO:0016972
GeneOntologyBiologicalProcessarabinose metabolic process

OTOGL OTOG

4.06e-0521322GO:0019566
GeneOntologyBiologicalProcessvibrational conductance of sound to the inner ear

OTOGL OTOG

4.06e-0521322GO:0055127
GeneOntologyBiologicalProcessL-arabinose metabolic process

OTOGL OTOG

4.06e-0521322GO:0046373
GeneOntologyCellularComponentextracellular matrix

RELN MUC5B TECTA PLXNB2 F3 EFEMP1 IGFALS OTOGL LOX LPA LTBP2 BMPER FGG MUC2 USH2A MUC5AC PLSCR1 OTOG

1.33e-0765613018GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

RELN MUC5B TECTA PLXNB2 F3 EFEMP1 IGFALS OTOGL LOX LPA LTBP2 BMPER FGG MUC2 USH2A MUC5AC PLSCR1 OTOG

1.40e-0765813018GO:0030312
GeneOntologyCellularComponentmucus layer

MUC2 MUC5AC

1.15e-0431302GO:0070701
GeneOntologyCellularComponentcollagen-containing extracellular matrix

RELN PLXNB2 F3 EFEMP1 LOX LPA LTBP2 BMPER FGG MUC2 USH2A PLSCR1

1.19e-0453013012GO:0062023
GeneOntologyCellularComponentactivin receptor complex

ACVR1B ACVR2B

5.66e-0461302GO:0048179
GeneOntologyCellularComponentGolgi lumen

ERO1A MUC19 MUC5B MUC2 MUC5AC

6.00e-041091305GO:0005796
GeneOntologyCellularComponentclathrin adaptor complex

AP3B1 AP1G1 AP3M2

9.30e-04311303GO:0030131
MousePhenoabnormal olfactory bulb granule cell layer morphology

RELN PLXNB2 TSHZ1

1.71e-0571123MP:0009949
DomainC8

MUC19 MUC5B TECTA BMPER MUC2 MUC5AC OTOG

4.90e-13121297PF08742
DomainTIL

MUC19 MUC5B TECTA BMPER MUC2 MUC5AC OTOG

4.90e-13121297PF01826
DomainUnchr_dom_Cys-rich

MUC19 MUC5B TECTA BMPER MUC2 MUC5AC OTOG

1.05e-12131297IPR014853
DomainC8

MUC19 MUC5B TECTA BMPER MUC2 MUC5AC OTOG

1.05e-12131297SM00832
DomainTIL_dom

MUC19 MUC5B TECTA BMPER MUC2 MUC5AC OTOG

2.10e-12141297IPR002919
DomainVWF_type-D

MUC19 MUC5B TECTA BMPER MUC2 MUC5AC OTOG

6.91e-12161297IPR001846
DomainVWFD

MUC19 MUC5B TECTA BMPER MUC2 MUC5AC OTOG

6.91e-12161297PS51233
DomainVWD

MUC19 MUC5B TECTA BMPER MUC2 MUC5AC OTOG

6.91e-12161297SM00216
DomainVWD

MUC19 MUC5B TECTA BMPER MUC2 MUC5AC OTOG

6.91e-12161297PF00094
DomainVWC_out

MUC19 MUC5B TECTA NELL1 MUC2 MUC5AC OTOG

2.99e-11191297SM00215
DomainVWF_dom

MUC19 MUC5B TECTA NELL1 BMPER MUC2 MUC5AC OTOG

4.03e-10421298IPR001007
DomainVWFC_2

MUC19 MUC5B TECTA NELL1 BMPER MUC2 MUC5AC

6.72e-09381297PS50184
DomainVWC

MUC19 MUC5B TECTA NELL1 BMPER MUC2 MUC5AC

6.72e-09381297SM00214
DomainCT

MUC19 MUC5B MUC2 MUC5AC OTOG

3.48e-07221295SM00041
DomainCys_knot_C

MUC19 MUC5B MUC2 MUC5AC OTOG

6.91e-07251295IPR006207
DomainCTCK_2

MUC19 MUC5B MUC2 MUC5AC OTOG

6.91e-07251295PS01225
DomainVWFC_1

MUC5B NELL1 BMPER MUC2 MUC5AC

4.62e-06361295PS01208
DomainCTCK_1

MUC19 MUC5B MUC2 MUC5AC

6.17e-06181294PS01185
DomainWxxW_domain

MUC5B MUC2 MUC5AC

6.34e-0661293IPR025155
DomainMucin2_WxxW

MUC5B MUC2 MUC5AC

6.34e-0661293PF13330
DomainVWC

MUC5B NELL1 BMPER MUC5AC

3.91e-05281294PF00093
DomainERO1

ERO1B ERO1A

4.73e-0521292PF04137
DomainEro1

ERO1B ERO1A

4.73e-0521292IPR007266
DomainEGF-like_dom

RELN TECTA NELL1 EFEMP1 UMODL1 LTBP2 NOTCH3 OTOG SORL1

5.88e-052491299IPR000742
DomainSBF2

SBF1 SBF2

1.41e-0431292PF12335
DomainSBF1/SBF2

SBF1 SBF2

1.41e-0431292IPR022096
DomainEGF

RELN TECTA NELL1 EFEMP1 UMODL1 LTBP2 NOTCH3 SORL1

2.30e-042351298SM00181
DomainEGF_3

RELN NELL1 EFEMP1 UMODL1 LTBP2 NOTCH3 OTOG SORL1

2.30e-042351298PS50026
DomainEGF_CA

NELL1 EFEMP1 UMODL1 LTBP2 NOTCH3

3.24e-04861295PF07645
DomainZnf_C2H2-like

ZKSCAN2 ZMAT4 RLF HINFP ZNF544 ZNF684 ZNF436 HELZ2 ZNF479 ZNF431 TSHZ1 DHX34 ZNF714 ZNF426 ZNF639

3.97e-0479612915IPR015880
DomainZnF_C2H2

ZKSCAN2 ZMAT4 RLF HINFP ZNF544 ZNF684 ZNF436 HELZ2 ZNF479 ZNF431 TSHZ1 DHX34 ZNF714 ZNF426 ZNF639

4.64e-0480812915SM00355
DomainEGF-like_CS

RELN NELL1 EFEMP1 UMODL1 LTBP2 EPHA10 NOTCH3 SORL1

4.65e-042611298IPR013032
DomainScramblase

PLSCR5 PLSCR1

4.67e-0451292PF03803
DomainScramblase

PLSCR5 PLSCR1

4.67e-0451292IPR005552
DomainEGF_2

RELN NELL1 EFEMP1 UMODL1 LTBP2 EPHA10 NOTCH3 SORL1

5.14e-042651298PS01186
DomainEGF_Ca-bd_CS

NELL1 EFEMP1 UMODL1 LTBP2 NOTCH3

5.64e-04971295IPR018097
DomainEGF_CA

NELL1 EFEMP1 UMODL1 LTBP2 NOTCH3

6.19e-04991295PS01187
DomainASX_HYDROXYL

NELL1 EFEMP1 UMODL1 LTBP2 NOTCH3

6.48e-041001295PS00010
DomainPectin_lyas_fold

SHCBP1 PKHD1

6.97e-0461292IPR012334
DomainPbH1

SHCBP1 PKHD1

6.97e-0461292SM00710
Domain-

SHCBP1 PKHD1

6.97e-04612922.160.20.10
DomainPbH1

SHCBP1 PKHD1

6.97e-0461292IPR006626
DomainGrowth_fac_rcpt_

ERBB4 NELL1 EFEMP1 UMODL1 LTBP2 NOTCH3

7.54e-041561296IPR009030
DomainEGF_extracell

RELN NELL1 LTBP2 NOTCH3

7.85e-04601294IPR013111
DomainEGF_2

RELN NELL1 LTBP2 NOTCH3

7.85e-04601294PF07974
DomainEGF-type_Asp/Asn_hydroxyl_site

NELL1 EFEMP1 UMODL1 LTBP2 NOTCH3

8.44e-041061295IPR000152
DomainIRF-3

IRF7 IRF9

9.72e-0471292PF10401
DomainIRF-3

IRF7 IRF9

9.72e-0471292SM01243
DomainInterferon_reg_factor-3

IRF7 IRF9

9.72e-0471292IPR019471
DomainPectin_lyase_fold/virulence

SHCBP1 PKHD1

1.29e-0381292IPR011050
DomainZnf_C2H2

ZKSCAN2 ZMAT4 TRIM23 RLF HINFP ZNF544 ZNF684 ZNF436 ZNF479 ZNF431 TSHZ1 ZNF714 ZNF426 ZNF639

1.35e-0380512914IPR007087
DomainEGF_CA

NELL1 EFEMP1 UMODL1 LTBP2 NOTCH3

1.58e-031221295SM00179
DomainIRF

IRF7 IRF9

1.65e-0391292SM00348
DomainIRF

IRF7 IRF9

1.65e-0391292PF00605
DomainInterferon_reg_fac_CS

IRF7 IRF9

1.65e-0391292IPR019817
DomainSialidases

RELN SORL1

1.65e-0391292IPR011040
DomainInterferon_reg_fact_DNA-bd_dom

IRF7 IRF9

1.65e-0391292IPR001346
DomainIRF_1

IRF7 IRF9

1.65e-0391292PS00601
DomainIRF_2

IRF7 IRF9

1.65e-0391292PS51507
DomainEGF-like_Ca-bd_dom

NELL1 EFEMP1 UMODL1 LTBP2 NOTCH3

1.70e-031241295IPR001881
DomainEGF_1

RELN NELL1 EFEMP1 UMODL1 LTBP2 USH2A NOTCH3

1.98e-032551297PS00022
DomainActivin_recp

ACVR1B ACVR2B

2.05e-03101292PF01064
DomainActivin_recp

ACVR1B ACVR2B

2.05e-03101292IPR000472
DomainZINC_FINGER_C2H2_2

ZKSCAN2 RLF HINFP ZNF544 ZNF684 ZNF436 HELZ2 ZNF479 ZNF431 TSHZ1 ZNF714 ZNF426 ZNF639

2.75e-0377512913PS50157
DomainZINC_FINGER_C2H2_1

ZKSCAN2 RLF HINFP ZNF544 ZNF684 ZNF436 HELZ2 ZNF479 ZNF431 TSHZ1 ZNF714 ZNF426 ZNF639

2.81e-0377712913PS00028
DomainTGFB_receptor

ACVR1B ACVR2B

2.99e-03121292IPR000333
DomainKRAB

ZKSCAN2 ZNF544 ZNF684 ZNF436 ZNF479 ZNF431 ZNF714 ZNF426

3.45e-033581298PS50805
DomainMyotubularin-like_Pase_dom

SBF1 SBF2

4.08e-03141292IPR010569
DomainZP_2

TECTA UMODL1

4.08e-03141292PS51034
DomainZP_1

TECTA UMODL1

4.08e-03141292PS00682
DomainuDENN

SBF1 SBF2

4.08e-03141292SM00800
DomainPPASE_MYOTUBULARIN

SBF1 SBF2

4.08e-03141292PS51339
DomainMyotubularin_fam

SBF1 SBF2

4.08e-03141292IPR030564
DomainMyotub-related

SBF1 SBF2

4.08e-03141292PF06602
DomainKRAB

ZKSCAN2 ZNF544 ZNF684 ZNF436 ZNF479 ZNF431 ZNF714 ZNF426

4.13e-033691298SM00349
DomainKRAB

ZKSCAN2 ZNF544 ZNF684 ZNF436 ZNF479 ZNF431 ZNF714 ZNF426

4.20e-033701298IPR001909
DomainClathrin/coatomer_adapt-like_N

AP3B1 AP1G1

4.69e-03151292IPR002553
DomainuDENN

SBF1 SBF2

4.69e-03151292PF03456
DomainAdaptin_N

AP3B1 AP1G1

4.69e-03151292PF01602
DomainGlyco_hormone_CN

MUC5B MUC5AC

4.69e-03151292IPR006208
DomainCys_knot

MUC5B MUC5AC

4.69e-03151292PF00007
DomainZP

TECTA UMODL1

4.69e-03151292SM00241
DomainGRAM

SBF1 SBF2

5.33e-03161292SM00568
DomainDENN

SBF1 SBF2

5.33e-03161292SM00799
DomainDENN

SBF1 SBF2

5.33e-03161292PF02141
DomaindDENN

SBF1 SBF2

5.33e-03161292PF03455
DomainSMAD_dom-like

IRF7 IRF9

5.33e-03161292IPR017855
Domain-

IRF7 IRF9

5.33e-031612922.60.200.10
DomainUDENN

SBF1 SBF2

5.33e-03161292PS50946
DomainDDENN

SBF1 SBF2

5.33e-03161292PS50947
DomaindDENN

SBF1 SBF2

5.33e-03161292SM00801
DomaindDENN_dom

SBF1 SBF2

5.33e-03161292IPR005112
DomainuDENN_dom

SBF1 SBF2

5.33e-03161292IPR005113
DomainDENN

SBF1 SBF2

5.33e-03161292PS50211
DomainDENN_dom

SBF1 SBF2

5.33e-03161292IPR001194
DomainDUF1605

DHX35 DHX34

6.02e-03171292IPR011709
DomainZP_dom

TECTA UMODL1

6.02e-03171292IPR001507
DomainZona_pellucida

TECTA UMODL1

6.02e-03171292PF00100
DomainOB_NTP_bind

DHX35 DHX34

6.02e-03171292PF07717
DomainHA2

DHX35 DHX34

6.74e-03181292SM00847
PathwayREACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS

MUC19 MUC5B MUC2 MUC5AC

1.35e-05211014MM15706
Pubmed

Expression of Muc19/Smgc gene products during murine sublingual gland development: cytodifferentiation and maturation of salivary mucous cells.

MUC19 MUC5B MUC2 MUC5AC

3.14e-096134419110483
Pubmed

Mucin gene polymorphisms in otitis media patients.

MUC5B MUC2 MUC5AC

5.59e-083134319718741
Pubmed

Increased expression of MUC5AC and MUC5B promoting bacterial biofilm formation in chronic rhinosinusitis patients.

MUC5B MUC2 MUC5AC

2.23e-074134325638393
Pubmed

Expression of MUC1, MUC2, MUC5AC and MUC5B in mucinous lesions of the breast.

MUC5B MUC2 MUC5AC

2.23e-074134322269464
Pubmed

Notch3 and Jagged2 contribute to gastric cancer development and to glandular differentiation associated with MUC2 and MUC5AC expression.

MUC2 MUC5AC NOTCH3

2.23e-074134322691042
Pubmed

Expression of MUC2, MUC5AC, MUC5B, and MUC6 mucins in colorectal cancers and their association with the CpG island methylator phenotype.

MUC5B MUC2 MUC5AC

2.23e-074134323807779
Pubmed

Epigenetic regulation (DNA methylation, histone modifications) of the 11p15 mucin genes (MUC2, MUC5AC, MUC5B, MUC6) in epithelial cancer cells.

MUC5B MUC2 MUC5AC

2.23e-074134317471237
Pubmed

The mouse secreted gel-forming mucin gene cluster.

MUC5B MUC2 MUC5AC

2.23e-074134314984930
Pubmed

Effects of the Helicobacter pylori Virulence Factor CagA and Ammonium Ion on Mucins in AGS Cells.

MUC5B MUC2 MUC5AC

2.23e-074134329869461
Pubmed

Characterization of mouse muc6 and evidence of conservation of the gel-forming mucin gene cluster between human and mouse.

MUC5B MUC2 MUC5AC

2.23e-074134312676567
Pubmed

The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.

PLXNB2 EFEMP1 LOX LPA LTBP2 BMPER FGG MUC2

2.98e-07167134822159717
Pubmed

Polymorphism of human mucin genes in chest disease: possible significance of MUC2.

MUC5B MUC2 MUC5AC

5.56e-075134311062147
Pubmed

Differential expression of MUC genes in endometrial and cervical tissues and tumors.

MUC5B MUC2 MUC5AC

5.56e-075134316188033
Pubmed

Mucin gene expression in human laryngeal epithelia: effect of laryngopharyngeal reflux.

MUC19 MUC5B MUC2 MUC5AC

6.18e-0718134418834073
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

ERO1B MAP1B MBOAT7 ERO1A ACP1 PLXNB2 FOXRED2 EFEMP1 CNIH4 LOX PIGX LTN1 LTBP2 LTBR BMPER PLSCR1 NOTCH3 SORL1

8.98e-0712011341835696571
Pubmed

Otogelin, otogelin-like, and stereocilin form links connecting outer hair cell stereocilia to each other and the tectorial membrane.

TECTA OTOGL OTOG

9.02e-0611134331776257
Pubmed

Cloning and analysis of cDNA encoding a major airway glycoprotein, human tracheobronchial mucin (MUC5).

MUC5B MUC5AC

1.47e-05213427513696
Pubmed

The association between MUC5AC and MUC5B genes expression and remodeling progression in severe neutrophilic asthma: A direct relationship.

MUC5B MUC5AC

1.47e-052134237146737
Pubmed

MUC5AC and MUC5B Mucins Are Decreased in Cystic Fibrosis Airway Secretions.

MUC5B MUC5AC

1.47e-052134214988081
Pubmed

Mucin glycosylation changes in cystic fibrosis lung disease are not manifest in submucosal gland secretions.

MUC5B MUC5AC

1.47e-052134215563276
Pubmed

The expression of MUC5AC and MUC5B mucin genes in the mucosa of chronic rhinosinusitis and nasal polyposis.

MUC5B MUC5AC

1.47e-052134217621824
Pubmed

Muc5b is required for airway defence.

MUC5B MUC5AC

1.47e-052134224317696
Pubmed

Macrophages are related to goblet cell hyperplasia and induce MUC5B but not MUC5AC in human bronchus epithelial cells.

MUC5B MUC5AC

1.47e-052134222391959
Pubmed

Mucins MUC5AC and MUC5B Are Variably Packaged in the Same and in Separate Secretory Granules.

MUC5B MUC5AC

1.47e-052134235776514
Pubmed

The ocular surface phenotype of Muc5ac and Muc5b null mice.

MUC5B MUC5AC

1.47e-052134224327612
Pubmed

Defective function of GABA-containing synaptic vesicles in mice lacking the AP-3B clathrin adaptor.

AP3B1 AP3M2

1.47e-052134215492041
Pubmed

Notch3 signaling is associated with MUC5AC expression and favorable prognosis in patients with small intestinal adenocarcinomas.

MUC5AC NOTCH3

1.47e-052134224810798
Pubmed

Gel-forming mucins form distinct morphologic structures in airways.

MUC5B MUC5AC

1.47e-052134228607090
Pubmed

Mucolytic activity of bacterial and human chitinases.

MUC2 MUC5AC

1.47e-052134217321686
Pubmed

Muc5b is mainly expressed and sialylated in the nasal olfactory epithelium whereas Muc5ac is exclusively expressed and fucosylated in the nasal respiratory epithelium.

MUC5B MUC5AC

1.47e-052134231030254
Pubmed

Altered expression of MUC2 and MUC5AC in progression of colorectal carcinoma.

MUC2 MUC5AC

1.47e-052134220731025
Pubmed

The idiopathic pulmonary fibrosis honeycomb cyst contains a mucocilary pseudostratified epithelium.

MUC5B MUC5AC

1.47e-052134223527003
Pubmed

Up-regulation of MUC5AC and MUC5B mucin genes in nasopharyngeal respiratory mucosa and selective up-regulation of MUC5B in middle ear in pediatric otitis media with effusion.

MUC5B MUC5AC

1.47e-052134216540890
Pubmed

Blocking Notch3 Signaling Abolishes MUC5AC Production in Airway Epithelial Cells from Individuals with Asthma.

MUC5AC NOTCH3

1.47e-052134231922915
Pubmed

Abnormalities in MUC5AC and MUC5B Protein in Airway Mucus in Asthma.

MUC5B MUC5AC

1.47e-052134227845589
Pubmed

The cellular oxygen tension regulates expression of the endoplasmic oxidoreductase ERO1-Lalpha.

ERO1B ERO1A

1.47e-052134212752442
Pubmed

Contribution of mucus concentration and secreted mucins Muc5ac and Muc5b to the pathogenesis of muco-obstructive lung disease.

MUC5B MUC5AC

1.47e-052134227435107
Pubmed

Mucins MUC5B and MUC5AC in Distal Airways and Honeycomb Spaces: Comparison among Idiopathic Pulmonary Fibrosis/Usual Interstitial Pneumonia, Fibrotic Nonspecific Interstitial Pneumonitis, and Control Lungs.

MUC5B MUC5AC

1.47e-052134226871672
Pubmed

Studies of mucus in mouse stomach, small intestine, and colon. II. Gastrointestinal mucus proteome reveals Muc2 and Muc5ac accompanied by a set of core proteins.

MUC2 MUC5AC

1.47e-052134223832517
Pubmed

Studies of mucus in mouse stomach, small intestine, and colon. III. Gastrointestinal Muc5ac and Muc2 mucin O-glycan patterns reveal a regiospecific distribution.

MUC2 MUC5AC

1.47e-052134223832516
Pubmed

Distinct roles for the Charcot-Marie-Tooth disease-causing endosomal regulators Mtmr5 and Mtmr13 in axon radial sorting and Schwann cell myelination.

SBF1 SBF2

1.47e-052134234718573
Pubmed

In silico cloning of mouse Muc5b gene and upregulation of its expression in mouse asthma model.

MUC5B MUC5AC

1.47e-052134211587997
Pubmed

Pathophysiological relevance of sputum MUC5AC and MUC5B levels in patients with mild asthma.

MUC5B MUC5AC

1.47e-052134234656442
Pubmed

Intestinal MUC2 and gastric M1/MUC5AC in preneoplastic lesions induced by 1,2-dimethylhydrazine in rat: a sequential analysis.

MUC2 MUC5AC

1.47e-052134217203232
Pubmed

Airway mucin MUC5AC and MUC5B concentrations and the initiation and progression of chronic obstructive pulmonary disease: an analysis of the SPIROMICS cohort.

MUC5B MUC5AC

1.47e-052134234058148
Pubmed

Endoplasmic reticulum oxidoreductin 1-lbeta (ERO1-Lbeta), a human gene induced in the course of the unfolded protein response.

ERO1B ERO1A

1.47e-052134210818100
Pubmed

C-Mannosylation of MUC5AC and MUC5B Cys subdomains.

MUC5B MUC5AC

1.47e-052134214718370
Pubmed

Methylation status of promoters and expression of MUC2 and MUC5AC mucins in pancreatic cancer cells.

MUC2 MUC5AC

1.47e-052134212527922
Pubmed

Mucin production during prenatal and postnatal murine lung development.

MUC5B MUC5AC

1.47e-052134221653907
Pubmed

MUC5B mobilizes and MUC5AC spatially aligns mucociliary transport on human airway epithelium.

MUC5B MUC5AC

1.47e-052134236427316
Pubmed

Transcription factor redundancy ensures induction of the antiviral state.

IRF7 IRF9

1.47e-052134220943654
Pubmed

Oxidative protein folding by an endoplasmic reticulum-localized peroxiredoxin.

ERO1B ERO1A

1.47e-052134221145486
Pubmed

Association of FHL5 and LPA genetic polymorphisms with diabetes mellitus risk: a case-control study.

LPA FHL5

1.47e-052134237452735
Pubmed

Mucin deficiency causes functional and structural changes of the ocular surface.

MUC5B MUC5AC

1.47e-052134223272068
Pubmed

Younger patients with COME are more likely to have mucoid middle ear fluid containing mucin MUC5B.

MUC5B MUC5AC

1.47e-052134227729120
Pubmed

De novo NUF2 variant in a novel inherited bone marrow failure syndrome including microcephaly and renal hypoplasia.

MUC5B MUC5AC

1.47e-052134236111525
Pubmed

In vivo glycosylation of mucin tandem repeats.

MUC2 MUC5AC

1.47e-052134211445551
Pubmed

Glutathione limits Ero1-dependent oxidation in the endoplasmic reticulum.

ERO1B ERO1A

1.47e-052134215161913
Pubmed

Stimulation of P2 (P2X7) receptors in human dendritic cells induces the release of tissue factor-bearing microparticles.

F3 P2RX7

1.47e-052134217314141
Pubmed

[Interleukin-1beta induces MUC2/MUC5B gene expression in human nasal epithelial cells].

MUC5B MUC2

1.47e-052134220873538
Pubmed

Similar phenotypes caused by mutations in OTOG and OTOGL.

OTOGL OTOG

1.47e-052134224378291
Pubmed

Temporal analysis of goblet cells and mucin gene expression in murine models of allergic asthma.

MUC2 MUC5AC

1.47e-052134214594655
Pubmed

Normal murine respiratory tract has its mucus concentrated in clouds based on the Muc5b mucin.

MUC5B MUC5AC

1.47e-052134232348677
Pubmed

Reassessment of the importance of mucins in determining sputum properties in cystic fibrosis.

MUC5B MUC5AC

1.47e-052134224332705
Pubmed

Abnormal subcellular distribution of mature MUC2 and de novo MUC5AC mucins in adenomas of the rectum: immunohistochemical detection using non-VNTR antibodies to MUC2 and MUC5AC peptide.

MUC2 MUC5AC

1.47e-052134212820724
Pubmed

Foxp1/4 control epithelial cell fate during lung development and regeneration through regulation of anterior gradient 2.

MUC5B MUC2 MUC5AC NOTCH3

1.91e-0541134422675208
Pubmed

Cell type-specific Rab32 and Rab38 cooperate with the ubiquitous lysosome biogenesis machinery to synthesize specialized lysosome-related organelles.

AP3B1 AP1G1 AP3M2

3.02e-0516134323247405
Pubmed

High-Mobility Group Box 1 Upregulates MUC5AC and MUC5B Expression in Primary Airway Epithelial Cells.

MUC5B MUC5AC

4.41e-053134229286856
Pubmed

Lack of plasminogen leads to milk stasis and premature mammary gland involution during lactation.

LPA FGG

4.41e-053134216949567
Pubmed

Nebulized Menthol Impairs Mucociliary Clearance via TRPM8 and MUC5AC/MUC5B in Primary Airway Epithelial Cells.

MUC5B MUC5AC

4.41e-053134236675209
Pubmed

Correlation of D dimer and factor VIII levels with histopathology in patients with breast carcinoma.

F3 FGG

4.41e-053134221694469
Pubmed

Differences in the expression of mucins in various forms of cystitis glandularis.

MUC2 MUC5AC

4.41e-053134217659847
Pubmed

Th2 cytokines orchestrate the secretion of MUC5AC and MUC5B in IL-5-positive chronic rhinosinusitis with nasal polyps.

MUC5B MUC5AC

4.41e-053134229802623
Pubmed

Cadherin-catenin adhesion system and mucin expression: a comparison between young and older patients with gastric carcinoma.

MUC2 MUC5AC

4.41e-053134218825309
Pubmed

DHX34 and NBAS form part of an autoregulatory NMD circuit that regulates endogenous RNA targets in human cells, zebrafish and Caenorhabditis elegans.

NBAS DHX34

4.41e-053134223828042
Pubmed

Adenomatous and foveolar gastric dysplasia: distinct patterns of mucin expression and background intestinal metaplasia.

MUC2 MUC5AC

4.41e-053134218300795
Pubmed

Resistin upregulates MUC5AC/B mucin gene expression in human airway epithelial cells.

MUC5B MUC5AC

4.41e-053134229604272
Pubmed

Tissue factor deficiency causes cardiac fibrosis and left ventricular dysfunction.

F3 FGG

4.41e-053134212426405
Pubmed

Expression of aberrant mucins in lobular carcinoma with histiocytoid feature of the breast.

MUC2 MUC5AC

4.41e-053134217333267
Pubmed

Aquaporin 5 expression increases mucin production in lung adenocarcinoma.

MUC5B MUC5AC

4.41e-053134221455588
Pubmed

Expression of leptin receptor in nasal polyps: leptin as a mucosecretagogue.

MUC5B MUC5AC

4.41e-053134220422702
Pubmed

Plasmin-driven fibrinolysis facilitates skin tumor growth in a gender-dependent manner.

LPA FGG

4.41e-053134222815383
Pubmed

Interleukin-33 induces mucin gene expression and goblet cell hyperplasia in human nasal epithelial cells.

MUC5B MUC5AC

4.41e-053134227776277
Pubmed

Lifetime imaging of a fluorescent protein sensor reveals surprising stability of ER thiol redox.

ERO1B ERO1A

4.41e-053134223589496
Pubmed

Manipulation of oxidative protein folding and PDI redox state in mammalian cells.

ERO1B ERO1A

4.41e-053134211707400
Pubmed

Autophagy of mucin granules contributes to resolution of airway mucous metaplasia.

MUC5B MUC5AC

4.41e-053134234158522
Pubmed

Gene expression profiling of colorectal mucinous adenocarcinomas.

MUC2 MUC5AC

4.41e-053134220485009
Pubmed

An activin mutant with disrupted ALK4 binding blocks signaling via type II receptors.

ACVR1B ACVR2B

4.41e-053134215123686
Pubmed

IL-8 regulates mucin gene expression at the posttranscriptional level in lung epithelial cells.

MUC5B MUC5AC

4.41e-053134219596978
Pubmed

The neuronal form of adaptor protein-3 is required for synaptic vesicle formation from endosomes.

AP3B1 AP3M2

4.41e-053134211588176
Pubmed

Regulation of neuregulin 1beta1-induced MUC5AC and MUC5B expression in human airway epithelium.

MUC5B MUC5AC

4.41e-053134219556605
Pubmed

Clinicopathological and prognostic significance of MUC-2, MUC-4 and MUC-5AC expression in japanese gastric carcinomas.

MUC2 MUC5AC

4.41e-053134223464473
Pubmed

Endoplasmic reticulum thiol oxidase deficiency leads to ascorbic acid depletion and noncanonical scurvy in mice.

ERO1B ERO1A

4.41e-053134222981861
Pubmed

Meconium ileus in cystic fibrosis is not linked to central repetitive region length variation in MUC1, MUC2, and MUC5AC.

MUC2 MUC5AC

4.41e-053134224920497
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

MAP1B AP3B1 HNRNPU LIG4 EFEMP1 SBF1 AP1G1 SHCBP1 PRKAA1 DHX34 SORL1

4.61e-056501341138777146
Pubmed

Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.

RELN PLXNB2 EFEMP1 LPA LTBP2 FGG

6.28e-05175134628071719
Pubmed

A role of MAP1B in Reelin-dependent neuronal migration.

RELN MAP1B

8.80e-054134215590913
Pubmed

Lefty blocks a subset of TGFbeta signals by antagonizing EGF-CFC coreceptors.

ACVR1B ACVR2B

8.80e-054134214966532
Pubmed

NODAL secreted by male germ cells regulates the proliferation and function of human Sertoli cells from obstructive azoospermia and nonobstructive azoospermia patients.

ACVR1B ACVR2B

8.80e-054134226289399
Pubmed

ERO1-beta, a pancreas-specific disulfide oxidase, promotes insulin biogenesis and glucose homeostasis.

ERO1B ERO1A

8.80e-054134220308425
InteractionZNF408 interactions

KIAA0232 TRIM23 SMYD2 EFEMP1 SHCBP1 LTBP2 FHL5 NOTCH3 SORL1

3.71e-071451289int:ZNF408
Cytoband11p15.5

IRF7 MUC5B TSPAN4 MUC2 MUC5AC

2.64e-05118134511p15.5
Cytoband22q13.33

PLXNB2 TTLL8 SBF1

1.90e-0438134322q13.33
CytobandEnsembl 112 genes in cytogenetic band chr11p15

IRF7 MUC5B NELL1 SBF2 TSPAN4 MUC2 MUC5AC OTOG

2.66e-045641348chr11p15
Cytoband12q12

ASIC1 MUC19 RND1

3.59e-0447134312q12
GeneFamilyCD molecules|Mucins

MUC19 MUC5B MUC2 MUC5AC

3.67e-0621934648
GeneFamilyPhospholipid scramblases

PLSCR5 PLSCR1

2.59e-045932954
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZKSCAN2 RLF HINFP ZNF544 ZNF684 ZNF436 ZNF479 ZNF431 TSHZ1 ZNF714 ZNF426 ZNF639

3.07e-04718931228
GeneFamilyMyotubularins|Phosphoinositide phosphatases

SBF1 SBF2

2.63e-0315932903
GeneFamilyDEAH-box helicases

DHX35 DHX34

3.00e-0316932500
CoexpressionNABA_ECM_GLYCOPROTEINS

RELN TECTA NELL1 EFEMP1 IGFALS OTOGL LTBP2 BMPER FGG OTOG

5.18e-0819113310MM17059
CoexpressionNABA_ECM_GLYCOPROTEINS

RELN TECTA NELL1 EFEMP1 IGFALS LTBP2 BMPER FGG USH2A OTOG

6.61e-0819613310M3008
CoexpressionNABA_CORE_MATRISOME

RELN TECTA NELL1 EFEMP1 IGFALS OTOGL LTBP2 BMPER FGG OTOG

1.26e-0627013310MM17057
CoexpressionNABA_CORE_MATRISOME

RELN TECTA NELL1 EFEMP1 IGFALS LTBP2 BMPER FGG USH2A OTOG

1.49e-0627513310M5884
CoexpressionNABA_MATRISOME

RELN MUC19 MUC5B TECTA PLXNB2 NELL1 EFEMP1 IGFALS OTOGL LOX LPA LTBP2 BMPER FGG SEMA4A MUC2 MUC5AC OTOG

3.58e-06100813318MM17056
CoexpressionNABA_MATRISOME

RELN MUC19 MUC5B TECTA PLXNB2 NELL1 EFEMP1 IGFALS LOX LPA LTBP2 BMPER FGG SEMA4A MUC2 USH2A MUC5AC OTOG

4.57e-06102613318M5889
CoexpressionGSE3982_DC_VS_NEUTROPHIL_LPS_STIM_DN

ERO1B ZMAT4 IRF9 KCTD20 MUC5AC FHL5 ZNF639 SORL1

6.93e-061941338M5393
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Igfbp6_Pltp|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

RELN ERBB4 PENK ZMAT4 F3 NELL1 TSHZ1 BMPER

1.02e-0813913489e9f29f92dbe65b26cc78b3a1c00778c6a701f5b
ToppCellLPS_only-Unknown-Endothelial|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ZMAT4 TLR8 SLCO1C1 SLC28A1 REPS2 FHL5 NOTCH3

5.95e-081151347ad5298c2ad8bf94fa13c2e50b0799e929473ef59
ToppCellLPS_only-Unknown|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ZMAT4 TLR8 SLCO1C1 SLC28A1 REPS2 FHL5 NOTCH3

5.95e-0811513477a733f6987b40ec497a03734b79ed5355ad3a2fc
ToppCellLPS_only-Unknown-Endothelial-Pericyte_2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ZMAT4 TLR8 SLCO1C1 SLC28A1 REPS2 FHL5 NOTCH3

5.95e-081151347c67145d3cd9243994a141749b426ff2a6dcc8d93
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN MUC5B OTOGL PKHD1 SPAG17 USH2A EPHA10 OTOG

9.02e-0818413482cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN MUC5B OTOGL PKHD1 SPAG17 USH2A EPHA10 OTOG

9.02e-081841348ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN MUC5B OTOGL PKHD1 SPAG17 USH2A EPHA10 OTOG

9.02e-0818413482b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellLPS-IL1RA-Unknown-Endothelial-Pericyte_2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RELN CPE RND1 SHCBP1 FHL5 NOTCH3 WDR72

1.06e-0712513472938a1d62afe1e0a3abba5eb92f07b886cc0accd
ToppCell3'-GW_trimst-2-SmallIntestine-Mesenchymal-Pericytes-angiogenic_pericyte|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RERG MAP1B TMEM74 CPE LTBP2 FHL5 NOTCH3 OTOG

1.06e-0718813480a5b93c131ce8514e996b0c2f39e0fc98636c122
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MAP1B ASIC1 CPE F3 SSPN EFEMP1 LOX LTBP2

1.25e-071921348f88aba74d6e8c594c32fe2bc095b5da28b4b28e9
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-Degenerative_Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MAP1B ASIC1 CPE F3 SSPN EFEMP1 LOX LTBP2

1.25e-07192134841a8326cd5bc19ad5041068501bab4c72399222e
ToppCellCOVID-19-kidney-Epi_(Mes)|COVID-19 / Disease (COVID-19 only), tissue and cell type

RERG RELN ERBB4 TSPAN5 CFAP54 PKHD1 WDR72

1.16e-061781347544379f5a6145429762258d426b876bb36c112f5
ToppCell10x3'2.3-week_12-13-Mesenchymal_osteo-stroma-osteoblast|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

RERG MAP1B CPE LOX TRIM17 BMPER WDR72

1.34e-061821347193cb2df3d7ea4cb9a11390b92955e7d9b0a053a
ToppCell3'-Child04-06-SmallIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RELN ABLIM3 TSPAN5 SMYD2 EFEMP1 LOX TSPAN4

1.55e-06186134730dd4164c101006c8d95922d89652b82dbe4b5ea
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RERG RELN SHISA2 F3 TSPAN5 CLIC5 LOX

2.06e-06194134743eb677a76634bb9a48a40e0d607c4936ae64bcc
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MAP1B CPE F3 SSPN EFEMP1 LOX LTBP2

2.13e-06195134747762d9e442fb1f6f0033e3e10f4c6e498d2c081
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MAP1B PENK CPE PLXNB2 F3 EFEMP1 LOX

2.20e-061961347b8b9801181d7604871b48aebacb295d0a57a5eaf
ToppCelltumor_Lung-Endothelial_cells-Lymphatic_ECs|Endothelial_cells / Location, Cell class and cell subclass

RELN MAP1B TSPAN5 SMYD2 EFEMP1 LOX TSPAN4

2.28e-061971347a05237ee6d31d9eab491dd7007859d6285cf1424
ToppCell10x3'2.3-week_12-13-Mesenchymal_osteo-stroma|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

MAP1B CPE SSPN EFEMP1 LOX TRIM17 NOTCH3

2.28e-06197134763b63c6b2f842adb87bc83222ff86796bd9b58f6
ToppCell10x3'2.3-week_12-13-Mesenchymal_osteo|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

MAP1B CPE SSPN EFEMP1 LOX TRIM17 NOTCH3

2.28e-061971347fb50903b87498b400c8e16e6a561b6d9458e5d97
ToppCell5'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RELN HSPA12B ABLIM3 TSPAN5 EFEMP1 LOX TSPAN4

2.35e-0619813475d42f4fda2081ea3e9f62a00e7eea702e0d0be7d
ToppCell10x5'v1-week_14-16-Mesenchymal_osteo-stroma-osteoblast_precursor|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

LRRC8E MAP1B CPE SSPN EFEMP1 LOX NOTCH3

2.35e-061981347bc9c9f2c87282b5ef8514773e065d2a6b5dde338
ToppCell3'-Broncho-tracheal-Mesenchymal|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RERG MAP1B PENK CPE SSPN LTBP2 NOTCH3

2.35e-0619813474961a3e9b953679648586afed04869ff36b81820
ToppCell5'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC6_(ADAMTS4+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RELN HSPA12B ABLIM3 TSPAN5 EFEMP1 LOX TSPAN4

2.35e-06198134799d6a64f3410dae3019161feef20a8f06081a24b
ToppCellParenchymal-10x5prime-Endothelial-Endothelia_lymphatic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

RELN MAP1B HSPA12B ABLIM3 TSPAN5 EFEMP1 LOX

2.43e-0619913471587d24b19f5bb64a3b6cc1df87c7c472cf41672
ToppCellParenchymal-10x5prime-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

RELN MAP1B HSPA12B ABLIM3 TSPAN5 EFEMP1 LOX

2.43e-061991347a9c2041e54899cb8ccc026758647f3ae3ca457dd
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-Pericytes-angiogenic_pericyte|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RERG MAP1B TMEM74 CPE LTBP2 FHL5 NOTCH3

2.43e-0619913479e32644b93fb1c4946dbe388fd5c357304d14e36
ToppCellproximal-3-mesenchymal|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

RERG MAP1B CPE SSPN LTBP2 FHL5 NOTCH3

2.52e-06200134794250991f78ea56810412d00a4bb645eb975478c
ToppCellmedial-2-mesenchymal|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

RERG MAP1B EFEMP1 LTBP2 BMPER FHL5 NOTCH3

2.52e-062001347a9d8aa5bcf383d98a9e2eaf4b1f8466982d6b088
ToppCelldistal-mesenchymal|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

RERG MAP1B SSPN EFEMP1 LTBP2 FHL5 NOTCH3

2.52e-062001347b54137a4545690f51e154bb05964eaa650c3ca8e
ToppCell10x5'v1-week_14-16-Mesenchymal_osteo-stroma-early_osteoblast|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

LRRC8E MAP1B SHISA2 CPE LOX TRIM17 NOTCH3

2.52e-06200134716a7c398626b6e82b394eb3ef013bda3a788659d
ToppCelldistal-2-mesenchymal|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

RERG MAP1B EFEMP1 LTBP2 BMPER FHL5 NOTCH3

2.52e-06200134765a50f03b0027ccefb51b8f77afa283d4a3b3567
ToppCellproximal-mesenchymal|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

RERG MAP1B CPE SSPN LTBP2 FHL5 NOTCH3

2.52e-06200134729f3a5c85404c6537d6405d599ebae281e0d4d4f
ToppCelldistal-3-mesenchymal|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

RERG MAP1B SSPN EFEMP1 LTBP2 FHL5 NOTCH3

2.52e-0620013477a79a2de78325d4f1c4535969106a0a44249028c
ToppCellmedial-mesenchymal|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

RERG MAP1B EFEMP1 LTBP2 BMPER FHL5 NOTCH3

2.52e-0620013474f19e1e40966e27779bf77e8c170ed3ecc24353e
ToppCellBiopsy_Other_PF-Mesenchymal|Biopsy_Other_PF / Sample group, Lineage and Cell type

RERG MAP1B SSPN LOX LTBP2 FHL5 NOTCH3

2.52e-062001347d6fcdd48858b53b5a8d18ae14b2dc4d9af41b070
ToppCelldistal-2-mesenchymal-Pericyte|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

RERG MAP1B EFEMP1 LTBP2 BMPER FHL5 NOTCH3

2.52e-0620013474ee0b2f56c2652435fa78bf6b3c90cea28df74e0
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERBB4 TECTA OTOGL PKHD1 SLC28A1 USH2A

5.16e-06145134696712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ERBB4 TECTA OTOGL PKHD1 SLC28A1 USH2A

9.75e-061621346bf886e22ff2a20353499004b53f25fb9e6574896
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L3-5_THEMIS_UBE2F|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PIWIL4 ANKRD18B SMYD2 OTOGL GLIPR1L1 DNAH6

1.20e-051681346bfa1491e8d433933003778b274710d3a16d973cb
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OTOGL PKHD1 WDR89 LTBP2 USH2A DNAH6

1.24e-05169134612bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCellControl-Fibroblasts-Pericytes|Control / group, cell type (main and fine annotations)

RERG MAP1B SLCO1C1 BMPER FHL5 NOTCH3

1.33e-051711346080003f698f867935c2bfc55d241d3650f45a0ab
ToppCellfacs-Marrow-B-cells-24m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MUC19 CPE PKHD1 WDR89 USH2A WDR72

1.51e-051751346887e75fc90e59a6394d62f3c048a9cfdf6707725
ToppCellChildren_(3_yrs)-Mesenchymal-pericyte_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

RERG SLCO1C1 LTBP2 BMPER FHL5 NOTCH3

1.66e-051781346185b44700f06ec58b3c09c80520502166c965fd6
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_ZNF322P1|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RERG RELN ERBB4 PLSCR5 ASIC1 EFEMP1

1.66e-0517813462a36475c260088f69f3b8c282d910e5eaa5c5c2d
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

RERG MAP1B SHISA2 F3 CLIC5 LOX

1.66e-051781346edc7143dc9959d36057cb9471681a23afcbc8cce
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RERG MAP1B SHISA2 F3 CLIC5 LOX

1.77e-051801346d685fa2b013bc085dbef7c40956ed3043f83e483
ToppCellChildren_(3_yrs)-Mesenchymal-pericyte_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

RERG MAP1B OTOGL BMPER FHL5 NOTCH3

1.83e-051811346451b87ac95154bb80018b8dd245b4a6389d81411
ToppCell10x5'v1-week_12-13-Mesenchymal_osteo-stroma-osteoblast|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

RERG CPE LOX TRIM17 BMPER WDR72

1.89e-051821346ba066ff9029cc052b76e2330ec168cb2e9b7e498
ToppCellCOVID-19-kidney-Podocyte|kidney / Disease (COVID-19 only), tissue and cell type

RERG MAP1B SHISA2 F3 CLIC5 LOX

1.95e-051831346fb5e2a31b560126e1c04a386c24c365901c60ad7
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RERG MAP1B CPE EFEMP1 FHL5 NOTCH3

2.01e-051841346689a8af81a79a4bb3123cfa01958c953eab5de98
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-Pericytes-angiogenic_pericyte|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RERG MAP1B TMEM74 CPE FHL5 NOTCH3

2.07e-05185134635d39a1d04c871edcfb749653538dc5fd0054281
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MUC19 GPRC6A OTOGL PKHD1 SPAG17 USH2A

2.13e-05186134623b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCellChildren_(3_yrs)-Mesenchymal-pericyte_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

RERG SLCO1C1 OTOGL BMPER FHL5 NOTCH3

2.20e-05187134686250acf088ec0c4800a0dfa031b0d4f7e52c342
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.0.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RERG ACVR2B LIG4 MUC5AC DAGLA SORL1

2.20e-051871346f5a202d5f8eb57b57d80815ce98774e04c387383
ToppCellFetal_29-31_weeks-Mesenchymal-pericyte_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

RERG MAP1B SLCO1C1 ZNF479 FHL5 NOTCH3

2.26e-051881346ccddc08121caff958a2b6f9e278a018858af6b4d
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RERG MAP1B SHISA2 F3 CLIC5 LOX

2.26e-051881346047c4e0b03fc8334e38c48977e41d26dbe229d47
ToppCellnucseq-Mesenchymal-Myocytic-Myocytic_1-Pericyte|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

RERG MAP1B SLCO1C1 BMPER FHL5 NOTCH3

2.40e-0519013464eb92aef1ee868f4537483d19014d947b7684612
ToppCellnucseq-Mesenchymal-Myocytic-Myocytic_1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

RERG MAP1B SLCO1C1 BMPER FHL5 NOTCH3

2.40e-0519013467be4341e2909101d756f14031c21e705eb45e69a
ToppCellfacs-Pancreas-Endocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERO1B MAP1B CPE TSPAN5 NELL1 IGFALS

2.47e-051911346f76f3f5c7902a3659d8cbe470f96ce57c8a6744d
ToppCell3'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC6_(ADAMTS4+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RELN HSPA12B ABLIM3 EFEMP1 LOX TSPAN4

2.55e-051921346ee9a23a4f00424a50bd7907cf3b12dc50027877e
ToppCell3'-Distal_airway-Mesenchymal-Mesenchymal_Myocytic|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RERG MAP1B EFEMP1 BMPER FHL5 NOTCH3

2.62e-05193134687ce81ff5b27d9c4300826d76ff5a62e9c408d5d
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERO1B KIAA0232 CPE PLXNB2 IGFALS TSHZ1

2.62e-051931346471e65f02937bc18d7c5facdacdf1df58cf0f839
ToppCell10x5'v1-week_17-19-Mesenchymal_osteo-stroma-early_osteoblast|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

SHISA2 CPE TRIM17 BMPER NOTCH3 WDR72

2.62e-0519313465e46a9f65e85aca78f825fdef88a95b97eec8743
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MAP1B CPE F3 SSPN LOX NOTCH3

2.62e-0519313467fc3ab7261c88c1df71744bf5b17e8e46c4300e0
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERO1B KIAA0232 CPE PLXNB2 IGFALS TSHZ1

2.62e-051931346fe451b3295d77b2bd1ac25cf29310c85835a45fe
ToppCellnucseq-Mesenchymal-Myocytic|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

RERG MAP1B LTBP2 BMPER FHL5 NOTCH3

2.70e-0519413462d66091097e106c7bee22e5281f50724700bdf8d
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAAF4 ANKRD18B CFAP54 SLFN13 SPAG17 DNAH6

2.70e-0519413464a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCell(6)_Endothelial_cells-(6)_Endothelial-F_(Lymphatics)|(6)_Endothelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)

RELN MAP1B TSPAN5 SMYD2 EFEMP1 LOX

2.70e-0519413469441202d6fa2ffbef9277d48ae9bc98876c26ec5
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

RERG RELN F3 TSPAN5 SSPN CLIC5

2.70e-0519413461374600957c7d7f0b05fd2c1186f521b9096d4ef
ToppCell3'-Distal_airway-Mesenchymal|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RERG MAP1B EFEMP1 BMPER FHL5 NOTCH3

2.70e-051941346f5e3e675187afb6efa774f2a8d685efcf813de82
ToppCell3'-Broncho-tracheal-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-Smooth_muscle-Smooth_muscle_L.2.3.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RERG MAP1B CPE SLCO1C1 FHL5 NOTCH3

2.78e-051951346bbafea2262074beede78e286276a1927ecb80582
ToppCell343B-Endothelial_cells-Endothelial-F_(Lymphatics)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

RELN MAP1B TSPAN5 SMYD2 EFEMP1 LOX

2.78e-051951346fc75f04eb475c8139cc5c35e6be22e73fb2be9e6
ToppCell3'-Broncho-tracheal-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-Smooth_muscle|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RERG MAP1B CPE SLCO1C1 FHL5 NOTCH3

2.78e-051951346145c50fa60d9df162152be0a6c070213ebdb8119
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN ERO1B MAP1B CPE KDM5D TSHZ1

2.78e-0519513463e519cffa6144a62b06124642a14c9ff39b76554
ToppCelltumor_Lung-Fibroblasts-Smooth_muscle_cells|tumor_Lung / Location, Cell class and cell subclass

RERG MAP1B CPE LTBP2 FHL5 NOTCH3

2.78e-051951346ea9ff25020c2fcd1bab80e1829af0f4e4777de8b
ToppCellE18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RERG MAP1B PENK LOX TSHZ1 LTBP2

2.78e-0519513462414b158dc7bdec43a9671544bfb7ffc5f5168fd
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN ERO1B MAP1B CPE KDM5D TSHZ1

2.78e-0519513467796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell343B-Endothelial_cells-Endothelial-F_(Lymphatics)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

RELN MAP1B TSPAN5 SMYD2 EFEMP1 LOX

2.78e-05195134683d45ff5e5bc704448431149fffb2e4c1278f279
ToppCelldistal-Endothelial-Lymphatic-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

RELN MAP1B ABLIM3 TSPAN5 EFEMP1 LOX

2.78e-051951346f45c1349932ee7eb419cced8a4fdedae3610953f
ToppCellcellseq-Mesenchymal-Myocytic-Myocytic_1|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

RERG MAP1B EFEMP1 BMPER FHL5 NOTCH3

2.86e-051961346c373465e34e2dd581247962d59e0477aae877079
ToppCell356C-Fibroblasts-Fibroblast-K_(Pericytes)|356C / Donor, Lineage, Cell class and subclass (all cells)

RERG MAP1B SSPN LTBP2 FHL5 NOTCH3

2.86e-051961346a5cc4f76e1a3825aaccba9a686d7da6f7e4300ff
ToppCell5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-Pericytes-Immature_pericyte|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RERG SHISA2 ZMAT4 AP3M2 FHL5 NOTCH3

2.86e-051961346c16fbd23d9e117831b55ab3da5b08b22dd972432
ToppCell3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SHISA2 ABLIM3 F3 EFEMP1 SLCO1C1 BMPER

2.86e-05196134685507488f83d8f71b3ee2ad5e5aa0b6ad6193873
ToppCell356C-Fibroblasts-Fibroblast-K_(Pericytes)-|356C / Donor, Lineage, Cell class and subclass (all cells)

RERG MAP1B SSPN LTBP2 FHL5 NOTCH3

2.86e-051961346476812fc1422aca8010d771eff11fa6081f15a2d
ToppCellcellseq-Mesenchymal-Myocytic-Myocytic_1-Pericyte|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

RERG MAP1B EFEMP1 BMPER FHL5 NOTCH3

2.86e-0519613468b5337ccf74de90e8b89a02ac00671af1de2cfff
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RERG RELN F3 TSPAN5 CLIC5 LOX

2.86e-051961346545d2e4469924d333e3f655f559c899fa1260196
ToppCellParenchymal-NucSeq-Stromal-Pericyte-Muscle_pericyte_pulmonary|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

RERG MAP1B SLCO1C1 BMPER FHL5 NOTCH3

2.94e-051971346f66945f9007d59d4208849c7fd727f8519713fbc
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RERG MAP1B LTBP2 BMPER FHL5 NOTCH3

2.94e-05197134601249bd485a3734de87ae6ed9c749597f39c6335
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MAP1B PENK CPE TSPAN5 SSPN LOX

2.94e-0519713462744cc94883c5d0424677cf5093bbab622933e9b
ToppCellnormal_Lung-Endothelial_cells-Lymphatic_ECs|Endothelial_cells / Location, Cell class and cell subclass

RELN MAP1B TSPAN5 SMYD2 EFEMP1 LOX

2.94e-051971346c838d0f64e3b43a616a9e381b8139bfe9aa32da7
ToppCellParenchymal-NucSeq-Stromal-Pericyte|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

RERG MAP1B SLCO1C1 BMPER FHL5 NOTCH3

2.94e-05197134641dd312f46a2b983c8d864adeb6970c0ca4a8048
ToppCell390C-Endothelial_cells-Endothelial-F_(Lymphatics)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

RELN MAP1B TSPAN5 SMYD2 EFEMP1 LOX

2.94e-051971346c84e988c2ad06087aafda9e3b68e9e72fd0e75f1
ToppCell5'-Adult-SmallIntestine-Endothelial-lymphatic_endothelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RELN HSPA12B ABLIM3 TSPAN5 EFEMP1 TSPAN4

2.94e-051971346407231542fa1ffd540dcb61435c0575e71f59725
ToppCell390C-Endothelial_cells-Endothelial-F_(Lymphatics)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

RELN MAP1B TSPAN5 SMYD2 EFEMP1 LOX

2.94e-0519713466195f945b3fd6da07907619267d49e96d1044f8f
ToppCelldistal-3-mesenchymal-Vascular_Smooth_Muscle|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

RERG MAP1B CPE SSPN FHL5 NOTCH3

3.03e-05198134637ce7b485ffb207e75afd1b576b486c6d59fc136
ToppCelldistal-mesenchymal-Vascular_Smooth_Muscle-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

RERG MAP1B CPE SSPN FHL5 NOTCH3

3.03e-0519813465080767ff55326b7d94fca27d398237c4a15c1ed
ToppCellTransplant_Alveoli_and_parenchyma-Endothelial-Lymphatic|Endothelial / Tissue, Lineage and Cell class of Lung Cells from 10X

RELN MAP1B TSPAN5 SMYD2 EFEMP1 TSPAN4

3.03e-0519813467a99c341736a4a2ac48ef8e2f7951f21a7378946
ToppCellcellseq-Mesenchymal-Myocytic-Myocytic_2|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

RERG MAP1B SSPN LTBP2 FHL5 NOTCH3

3.03e-051981346c7075dce915ab8387309fcb12c5f6a17d4100cda
ToppCelldistal-2-mesenchymal-Vascular_Smooth_Muscle|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

RERG MAP1B SSPN LTBP2 FHL5 NOTCH3

3.03e-051981346ce05ede69c167b2294630709bb0c223483a6ef75
Drugtranexamic acid

ACVR1B ACVR2B F3 LPA TRIM17 FGG

2.01e-06641336CID000005526
Diseasebringing up phlegm, sputum or mucus on most days, self-reported

NELL1 MUC2 MUC5AC

6.57e-0691283EFO_0009824
Diseasecystitis (is_marker_for)

MUC2 MUC5AC

1.87e-0521282DOID:1679 (is_marker_for)
Diseasesputum mucin-5B amount

MUC2 MUC5AC

5.59e-0531282OBA_2050332
Diseasemucinous adenocarcinoma (is_marker_for)

MUC2 MUC5AC

1.85e-0451282DOID:3030 (is_marker_for)
Diseasechronic kidney disease, APOL1 risk genotype carrier status

OTOGL LPA

1.85e-0451282EFO_0003884, EFO_0009324
DiseaseOpioid abuse

PENK BMPER

2.77e-0461282C0029095
DiseaseOpiate Abuse

PENK BMPER

2.77e-0461282C4551628
DiseaseNarcotic Dependence

PENK BMPER

2.77e-0461282C1527402
DiseaseOpiate Addiction

PENK BMPER

2.77e-0461282C0524662
DiseaseNarcotic Abuse

PENK BMPER

2.77e-0461282C0524661
DiseaseOpioid-Related Disorders

PENK BMPER

2.77e-0461282C0027412
Diseasemigraine disorder, endometriosis

ERBB4 NELL1 SBF2 FHL5

2.92e-04731284EFO_0001065, MONDO_0005277
Disease6-bromotryptophan measurement

ERO1A FOXRED2

6.59e-0491282EFO_0800099
DiseaseAlzheimer disease, language impairment

ERBB4 KIAA0232

6.59e-0491282EFO_0005425, MONDO_0004975
DiseaseMalignant neoplasm of breast

ERBB4 TECTA F3 RXRB EFEMP1 OTOGL ZNF436 PRKAA1 TSPAN4 SLC28A1 REPS2 NOTCH3 SORL1

8.13e-04107412813C0006142
Diseaseautosomal dominant nonsyndromic deafness (is_implicated_in)

MAP1B EPHA10

1.00e-03111282DOID:0050564 (is_implicated_in)
Diseasepulmonary fibrosis

MUC5B MUC5AC

1.00e-03111282EFO_0009448
Diseasepneumonia

HELZ2 MUC2 MUC5AC

1.12e-03471283EFO_0003106
Diseaselevel of Phosphatidylinositol (18:0_20:3) in blood serum

MBOAT7 DAGLA

1.20e-03121282OBA_2045157
Diseasemood disorder

RELN SORL1

1.41e-03131282EFO_0004247
DiseaseMigraine Disorders

FHL5 NOTCH3

1.41e-03131282C0149931
DiseaseCharcot-Marie-Tooth disease type 4

SBF1 SBF2

1.41e-03131282cv:C4082197
Diseasemonokine induced by gamma interferon measurement

LIG4 UMODL1 LPA

1.51e-03521283EFO_0008236
Disease1-stearoyl-2-dihomo-linolenoyl-GPI (18:0/20:3n3 or 6) measurement

MBOAT7 DAGLA

1.64e-03141282EFO_0022085
DiseaseImpaired cognition

NOTCH3 SORL1

1.64e-03141282C0338656
Diseaseankle brachial index

NBAS LPA

2.15e-03161282EFO_0003912
DiseaseInsulin Resistance

CPE IGFALS PRKAA1

2.28e-03601283C0021655
DiseaseInsulin Sensitivity

CPE IGFALS PRKAA1

2.28e-03601283C0920563
Diseasecystic fibrosis (is_marker_for)

MUC5B MUC2 MUC5AC

2.50e-03621283DOID:1485 (is_marker_for)
Diseaseserum hepcidin measurement

F3 NELL1

2.73e-03181282EFO_0004504
Diseasecholangiocarcinoma (is_marker_for)

MUC5B MUC2 MUC5AC

2.74e-03641283DOID:4947 (is_marker_for)
Diseasecortical surface area change measurement, age at assessment

F3 BMPER

3.04e-03191282EFO_0008007, EFO_0021503
DiseaseColorectal Carcinoma

MAP1B CPE NELL1 OSBP EFEMP1 P2RX7 PKHD1 SPAG17 SORL1

3.60e-037021289C0009402
DiseaseDeep Vein Thrombosis

F3 LPA

3.71e-03211282C0149871
DiseaseVenous Thrombosis

F3 LPA

3.71e-03211282C0042487

Protein segments in the cluster

PeptideGeneStartEntry
NECFYEELNACSGRE

UMODL1

266

Q5DID0
CICAFASDETLAQEF

C2orf42

251

Q9NWW7
RNCSCSADIRDCDYS

C21orf62

41

Q9NYP8
ICIESCNLYDGEFRE

ERBB4

531

Q15303
QLYGTRCDSCRDFIT

ABLIM3

76

O94929
CTFLYQNDDVCDSAD

CFAP54

2771

Q96N23
ACAFCVYESLIEQSL

BLACE

146

A4D250
SSEDLRNTHCCYTDY

ACVR1B

86

P36896
DCLCDIDSIDNFNTY

ERO1B

41

Q86YB8
AEDYAFCCDLRSIQQ

ANKRD18B

236

A2A2Z9
VCSYDDDADELSVFC

IGFALS

46

P35858
SLISYTFVCRQEDFC

CD177

96

Q8N6Q3
YARDEFTNTCAADSE

CLIC5

381

Q9NZA1
CVYLLEAEASACTTD

ARMC12

96

Q5T9G4
IDFCDSTQTASFQLC

AP3B1

951

O00203
ERSEDCLCAALSSYV

MUC5B

656

Q9HC84
ECAVQFYFLCTVETA

OR5K2

96

Q8NHB8
DCCLLTFSVDDSQSF

RAB9A

81

P51151
RFCCQFITSVTALYD

INTS15

176

Q96N11
VSCDLACDLSAFFDS

LTN1

1276

O94822
TVRAECSQDCATCSY

PENK

21

P01210
CAAIRSSFREEDNTY

AP1G1

31

O43747
RSVCDYFFEAQERAT

AP3M2

26

P53677
LSNLCRFCDDILSSY

MTX3

226

Q5HYI7
ARQDVDLCLVSSCEY

MAP1B

2076

P46821
ECYDRSLCANTSLND

HHIPL1

446

Q96JK4
TDIDSDRHYCSCLTF

SBF2

71

Q86WG5
TCDYLCINFDFNTIR

KCTD20

201

Q7Z5Y7
FIDSYICQVCSRGDE

KDM5D

311

Q9BY66
GQRVYFAAEDTDCCT

PLSCR1

136

O15162
AVEESICFNRTFCST

PLSCR5

101

A0PG75
SRCVYEALCNTTSEC

PLXNB2

786

O15031
TDAELFSADVNNYCC

KIAA0232

846

Q92628
TCDTYSELSRLCASD

MUC19

686

Q7Z5P9
FCSAVASYAQECTKE

MUC2

1091

Q02817
DTCYFVNCSLSCTLE

MUC2

4356

Q02817
EHFDDTVVCLDTYNC

HNRNPU

281

Q00839
FTGTYCEVDIDECQS

NOTCH3

461

Q9UM47
NIDCYSTDFCVRVRD

MBOAT7

301

Q96N66
CRVETSEVTGYASFC

LRRC8E

286

Q6NSJ5
AYSTQTCFCNVADRL

MUC5AC

4776

P98088
CLSSANSLYDDIECF

IRF7

481

Q92985
NASTFCVCQDSYARS

EPHA10

311

Q5JZY3
ENCLDTDLRSFYAES

FOXRED2

586

Q8IWF2
INLYCCAAEDARFIT

HSPA12B

606

Q96MM6
TCLDSDACYEIFTES

NBAS

1111

A2RRP1
DACYEIFTESLLCSS

NBAS

1116

A2RRP1
CENSLEQLCYVAAFT

OSBP

466

P22059
YIRVDDFSCTEHDEC

NELL1

466

Q92832
ECAVQFYFLCTVETA

OR5K1

96

Q8NHB7
DFAASCSVTDSCYAI

RELN

2381

P78509
TDINSERHYCACLTF

SBF1

71

O95248
NCSRETVEFKCDYSS

GPRC6A

121

Q5T6X5
IDFLIDTYSSNCCRS

P2RX7

351

Q99572
SSTCVAYVATRDNCC

FGG

21

P02679
NICYEFNDSDRECAL

DNAH6

3711

Q9C0G6
ERLLCTECYSNECSS

FHL5

86

Q5TD97
FLYDNCTACTCRDST

BMPER

251

Q8N8U9
EDSDLQTCYCVFDVL

LIG4

356

P49917
DCADFHTYLSRCNSI

CRYGS

26

P22914
EVGYCIRFDDCTDQL

DHX35

131

Q9H5Z1
YLSSNCFEITVELSC

CPE

331

P16870
YCCEERSSFERNAFK

C1orf100

131

Q5SVJ3
EYCNLTRCSDTEGTV

LPA

1686

P08519
CTCDVETIDRFNNYR

ERO1A

46

Q96HE7
SFRCSCEQGYEVTSD

LTBP2

1031

Q14767
TSSRACDCVEVYLQS

FBXO24

216

O75426
LRCAAEENCLASTAY

LOX

236

P28300
VCVRDTDVFCTENYL

DNAAF4

26

Q8WXU2
FLCCTRTKDSQSDAY

DAGLA

201

Q9Y4D2
SNECVELFRTAYFCR

IRF9

316

Q00978
TQFYDFDSLSCSRVC

GLIPR1L1

121

Q6UWM5
SVDACVVAACYFSRL

HELZ2

1481

Q9BYK8
AYRCDFENCTFSARS

HINFP

311

Q9BQA5
CLTNDTDLYSDCLRT

DHX34

1051

Q14147
EQIVTYVADTCRCFF

SLFN13

786

Q68D06
TYSLRCHDCAVINDF

GML

26

Q99445
LDALENCCFDTSLEY

FOCAD

1121

Q5VW36
CSILYSDIFASCRNV

OTOGL

1136

Q3ZCN5
FLCSSDSTYQACVTA

OTOG

2371

Q6ZRI0
AECSQYLDETCTCFV

ISL2

56

Q96A47
NCEDIDECRTSSYLC

EFEMP1

291

Q12805
AVYSIECTCNFLSDI

RTTN

546

Q86VV8
QCDTCRENFYGLDVT

USH2A

776

O75445
VVSNCSCTREDYECD

SORL1

671

Q92673
CYSDSDAVLLCFDIS

RND1

81

Q92730
DSDFETVYQQCVRCC

ACP1

136

P24666
NCSVYESCVDCVLAR

SEMA4A

496

Q9H3S1
CSDRTEYVAESFLNC

PIWIL4

491

Q7Z3Z4
ALRYCCSSAEARLDQ

SHISA2

71

Q6UWI4
CVSYQVDERTCIQFS

SSPN

106

Q14714
EDSCEAARHTYVQCD

PKHD1

1806

P08F94
LFQDEDSCSDCSYRD

SHCBP1

36

Q8NEM2
SRYATVIANCEDSSC

SPAG17

1496

Q6Q759
LATELACAFYECSAC

RERG

136

Q96A58
DLTYSCRDNKDCTVD

RXRB

236

P28702
FECSEEEVLSCLYNR

PRKAA1

311

Q13131
FFDSYSITACRIDCE

ASIC1

301

P78348
DFNCYDRQECVATEE

ACVR2B

81

Q13705
TLSDLECDYINARSC

CNIH4

26

Q9P003
CQSTTYCRKDEFDNA

TEPP

121

Q6URK8
FVHSCVYDLCSVRDN

TECTA

546

O75443
SCELCAEENFSRSYP

TLR8

21

Q9NR97
CEECDKAFNRFSYLT

ZNF431

346

Q8TF32
RSYTVENAYECSECG

ZNF684

151

Q5T5D7
RCYSLCTESEQQEFL

TTLL8

191

A6PVC2
CEECDKAFNRFSYLT

ZNF714

286

Q96N38
QEEATCAICLDYFTD

TRIM11

11

Q96F44
YECTECEKSFSRSSA

ZNF436

446

Q9C0F3
CEQCDVQFSSSSELY

ZNF639

291

Q9UID6
CIFSAIDAVYCARFV

THOC2

986

Q8NI27
YARRDSQCIDCFQAF

PIGX

131

Q8TBF5
SEGEQQCYSELFARC

REPS2

31

Q8NFH8
SEVSSLNYCRSFCQT

RLF

66

Q13129
VYDITERKSFCSNFC

RPAP2

126

Q8IXW5
EQTLCVVCFSDFEAR

RNF44

376

Q7L0R7
LADTSDSCFLQFESC

TP53INP1

76

Q96A56
CVLFACNEASYLAEV

SERINC4

351

A6NH21
SYHERALFSDCNSRC

SLCO1C1

466

Q9NYB5
ESLNCQTIRFCTYTE

WDR72

211

Q3MJ13
CFYTTDTECDLTDEI

F3

81

P13726
SCDDFSSQELEIFIC

SLF1

656

Q9BQI6
SSFEIYQCCREAFQS

SLC28A1

611

O00337
YTCEECGQDFRRSSA

ZNF479

381

Q96JC4
RDTVCATCAENSYNE

LTBR

76

P36941
QEEATCSICLDYFTD

TRIM17

11

Q9Y577
IQTDFRCCGVSNYTD

TSPAN4

141

O14817
IYFNCTDSNASRERC

TSPAN5

166

P62079
SQYECDECRETCSES

ZNF544

296

Q6NX49
SETFRKCFRQFCYED

ZKSCAN2

41

Q63HK3
EYFTCALQHRADVSC

TTC37

701

Q6PGP7
VRFANSCDSVYSACT

WDR89

76

Q96FK6
NCCSQELETSFTYVD

TMEM74

101

Q96NL1
RCDEDEAHLASVYCT

TRIM23

126

P36406
NDRLRDSYFFTCECQ

SMYD2

251

Q9NRG4
DSYFFTCECQECTTK

SMYD2

256

Q9NRG4
IDQDLFTDSYCKVCS

ZMAT4

6

Q9H898
ADCLTDCYQDSVTFD

ZNF426

31

Q9BUY5
DSRAEACFVNCVERF

TIMM8A

56

O60220
FRCKDCSAAYDTLVE

TSHZ1

246

Q6ZSZ6
SSLQVLDADTFAFCC

WDR73

181

Q6P4I2