Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiondynein light intermediate chain binding

CCDC88B DNAH17 DNAH8 DNAH11

3.82e-05281374GO:0051959
GeneOntologyMolecularFunctionglutamine N-acyltransferase activity

GLYATL1 GLYATL1B

4.67e-0521372GO:0047946
GeneOntologyMolecularFunctiondynein intermediate chain binding

DNAH17 DNAH8 HTT DNAH11

1.17e-04371374GO:0045505
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNAH17 DNAH8 DNAH11

2.39e-04181373GO:0008569
GeneOntologyMolecularFunctionglycine N-acyltransferase activity

GLYATL1 GLYATL1B

4.61e-0451372GO:0047961
DomainTPR-like_helical_dom

IFT140 FEM1C TRANK1 HELZ STIP1 LONRF3 FEM1A SMG6 WDTC1

4.74e-052331349IPR011990
DomainDVL-1

DVL1P1 DVL1

5.11e-0521342IPR008340
DomainUbiquitin-rel_dom

UBQLN1 UBL3 FRMPD2 USP24 DVL1 DGKQ SACS TP53BP2

5.52e-051841348IPR029071
Domain-

FEM1C TRANK1 HELZ STIP1 LONRF3 FEM1A SMG6 WDTC1

1.26e-0420713481.25.40.10
DomainSTPPase_N

PPP1CA PPP1CC

1.53e-0431342IPR031675
DomainSTPPase_N

PPP1CA PPP1CC

1.53e-0431342PF16891
DomainARM-type_fold

UBQLN1 USP24 TSC2 CTIF HEATR1 XPO5 FHOD1 AP3D1 TBCD HTT

1.70e-0433913410IPR016024
DomainTPR_REGION

IFT140 FEM1C TRANK1 STIP1 LONRF3 FEM1A WDTC1

1.90e-041651347PS50293
DomainTPR

IFT140 FEM1C TRANK1 STIP1 LONRF3 FEM1A WDTC1

1.90e-041651347PS50005
DomainDishevelled

DVL1P1 DVL1

3.04e-0441342PF02377
DomainDishevelled_fam

DVL1P1 DVL1

3.04e-0441342IPR008339
DomainPBC

PBX1 PBX2

3.04e-0441342PF03792
DomainDishevelled_protein_dom

DVL1P1 DVL1

3.04e-0441342IPR003351
DomainPBX

PBX1 PBX2

3.04e-0441342IPR005542
DomainRhoGAP

ARHGAP10 ARHGAP35 CHN1 FAM13B

1.02e-03621344SM00324
DomainDIX

DVL1P1 DVL1

1.05e-0371342PF00778
DomainDIX

DVL1P1 DVL1

1.05e-0371342IPR001158
DomainDIX

DVL1P1 DVL1

1.05e-0371342PS50841
DomainDAX

DVL1P1 DVL1

1.05e-0371342SM00021
DomainRhoGAP

ARHGAP10 ARHGAP35 CHN1 FAM13B

1.09e-03631344PF00620
Domain-

TSC2 HEATR1 XPO5 FHOD1 AP3D1 TBCD HTT

1.12e-0322213471.25.10.10
DomainRhoGAP_dom

ARHGAP10 ARHGAP35 CHN1 FAM13B

1.15e-03641344IPR000198
DomainRHOGAP

ARHGAP10 ARHGAP35 CHN1 FAM13B

1.15e-03641344PS50238
Domain-

ARHGAP10 ARHGAP35 CHN1 FAM13B

1.15e-036413441.10.555.10
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

IFT140 ANK3 MYO1E ARHGAP10 RBMS1 ATG2B CDH23 MCM3 TSC2 HEATR1 EIF3CL PPP1CA DHX9 PPP1CC CNNM4 XPO5 HELZ VPS51 SNRNP200 TP53BP2 TBCD CDK4 WDTC1

2.87e-0913211392327173435
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

ZC3H14 ANK3 RBM10 ATG2B USP24 DVL1 MCM3 HEATR1 ARHGAP35 PPP1CA PEAK1 SNRNP200 TP53BP2 HTT

4.88e-085491391438280479
Pubmed

A human MAP kinase interactome.

IFT140 ANK3 CNTRL NEB CCDC88B FAM13B CDC42BPB FHOD1 MCM3AP HELZ MAPK7 SLC4A4 SNRNP200

8.70e-084861391320936779
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

PDE2A UBQLN1 ANK3 MYO1E PPRC1 RHOBTB3 MCF2L2 HECTD4 APBB2 TSC2 CACHD1 CDC42BPB SACS UBE3A ZNF197 DNM3 PBX1 PBX2 SNRNP200 SCAI

2.11e-0712851392035914814
Pubmed

CTDP1 regulates breast cancer survival and DNA repair through BRCT-specific interactions with FANCI.

RNF213 TSC2 FHOD1 MCM3AP HELZ TBCD HTT

2.15e-07104139731240132
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

ATP6V1E1 PDE2A ANK3 MYO1E ARHGAP35 CDC42BPB EIF3CL PPP1CA DHX9 PPP1CC SACS STON2 STIP1 PEAK1 SLC4A4 VPS51 SNRNP200 AP3D1 TP53BP2 SCAI DNAH11

2.68e-0714311392137142655
Pubmed

Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.

IFT140 MCF2L2 CACHD1 BAHD1 MCM3AP SNRNP200 WDTC1

9.81e-07130139712421765
Pubmed

Molecular mechanisms underlying the interaction of protein phosphatase-1c with ASPP proteins.

PPP1CA PPP1CC TP53BP2

1.24e-066139323088536
Pubmed

Inhibitory member of the apoptosis-stimulating proteins of the p53 family (iASPP) interacts with protein phosphatase 1 via a noncanonical binding motif.

PPP1CA PPP1CC TP53BP2

1.24e-066139321998301
Pubmed

Mutations in DNAH17, Encoding a Sperm-Specific Axonemal Outer Dynein Arm Heavy Chain, Cause Isolated Male Infertility Due to Asthenozoospermia.

DNAH17 DNAH8 DNAH11

2.16e-067139331178125
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

PDE2A MYO1E PPRC1 HECTD4 DVL1 DGKQ TSC2 ARHGAP35 CDC42BPB BAHD1 PLEKHG1 MCM3AP FEM1A AP3D1 TBCD HTT SMG6

2.18e-0611051391735748872
Pubmed

Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.

POLB USP24 DVL1 HEATR1 ARHGAP35 CDC42BPB DHX9 SACS XPO5 STIP1 TBCD

5.60e-064981391136634849
Pubmed

FEM1 proteins are ancient regulators of SLBP degradation.

CTIF FEM1C FEM1A

7.34e-0610139328118078
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

PDE2A ANK3 HECTD4 MCM3 TSC2 CDC42BPB PPP1CA PPP1CC UBE3A STON2 DNM3 STIP1 SLC4A4 TP53BP2 SMG6

7.76e-069631391528671696
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

ANK3 ARHGAP10 FRMPD2 INSR HECTD4 APBB2 RNF213 CTIF AHCYL2 FOXN3 ARHGAP35 CDC42BPB F7 CNNM4 PBX1 PBX2 TBCD HTT SMG6

7.94e-0614891391928611215
Pubmed

Identification of the human testis protein phosphatase 1 interactome.

PPP1CA PPP1CC SPOCD1 TP53BP2 SMG6

8.08e-0668139521382349
Pubmed

Enhancer Activity Requires CBP/P300 Bromodomain-Dependent Histone H3K27 Acetylation.

MCM3 PPP1CA PPP1CC XPO5 DNM3 STIP1 SNRNP200

8.50e-06180139730110629
Pubmed

A directed protein interaction network for investigating intracellular signal transduction.

IFT140 ATP6V1E1 DVL1 MYOZ3 MCM3 TSC2 CHN1 BAHD1 SERPINA4 MID1IP1 UBE3A MCM3AP FGB VPS51 TP53BP2 CDK4

1.17e-0511241391621900206
Pubmed

Comprehensive proteomic analysis of interphase and mitotic 14-3-3-binding proteins.

PDE3A ARHGAP10 HECTD4 MCM3 TSC2 DHX9 TP53BP2

1.21e-05190139715161933
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

ANK3 ATG2B USP24 DVL1 AHCYL2 ARHGAP35 CDC42BPB EIF3CL PPP1CA PPP1CC UBE3A HELZ STIP1 PEAK1 SLC4A4 VPS51

1.37e-0511391391636417873
Pubmed

Interaction proteome of human Hippo signaling: modular control of the co-activator YAP1.

DVL1 PPP1CA PPP1CC MOB1B STIP1 PEAK1 AP3D1 TP53BP2

1.39e-05270139824366813
Pubmed

Ubiquitination, localization, and stability of an anti-apoptotic BCL2-like protein, BCL2L10/BCLb, are regulated by Ubiquilin1.

UBQLN1 BCL2L10

1.59e-052139222233804
Pubmed

Epigenetic Regulation of Phosphodiesterases 2A and 3A Underlies Compromised β-Adrenergic Signaling in an iPSC Model of Dilated Cardiomyopathy.

PDE2A PDE3A

1.59e-052139226095046
Pubmed

E3 ubiquitin ligase E6AP-mediated TSC2 turnover in the presence and absence of HPV16 E6.

TSC2 UBE3A

1.59e-052139218298802
Pubmed

MCM3AP, a novel acetyltransferase that acetylates replication protein MCM3.

MCM3 MCM3AP

1.59e-052139211258703
Pubmed

Protein phosphatase 1 interacts with p53BP2, a protein which binds to the tumour suppressor p53.

PPP1CC TP53BP2

1.59e-05213928549741
Pubmed

Fibrinogen and factor VII promoter polymorphisms in women with preeclampsia.

F7 FGB

1.59e-052139212151156
Pubmed

Spermiogenesis is impaired in mice bearing a targeted mutation in the protein phosphatase 1cgamma gene.

PPP1CA PPP1CC

1.59e-05213929882500
Pubmed

Human homologue sequences to the Drosophila dishevelled segment-polarity gene are deleted in the DiGeorge syndrome.

DVL1P1 DVL1

1.59e-05213928644734
Pubmed

Coagulation gene polymorphisms as risk factors for myocardial infarction in young Indian Asians.

F7 FGB

1.59e-052139216049588
Pubmed

Identification of a novel MCM3-associated protein that facilitates MCM3 nuclear localization.

MCM3 MCM3AP

1.59e-05213929712829
Pubmed

Fusion with E2A converts the Pbx1 homeodomain protein into a constitutive transcriptional activator in human leukemias carrying the t(1;19) translocation.

PBX1 PBX2

1.59e-05213927910944
Pubmed

Identification of human FEM1A, the ortholog of a C. elegans sex-differentiation gene.

FEM1C FEM1A

1.59e-052139211733146
Pubmed

PP-1α and PP-1γ display antagonism and differential roles in tumorigenicity of lung cancer cells.

PPP1CA PPP1CC

1.59e-052139223176181
Pubmed

Ubiquilin interacts and enhances the degradation of expanded-polyglutamine proteins.

UBQLN1 HTT

1.59e-052139217603015
Pubmed

Differential ubiquitination and degradation of huntingtin fragments modulated by ubiquitin-protein ligase E3A.

UBE3A HTT

1.59e-052139224706802
Pubmed

Differential regulation of human platelet responses by cGMP inhibited and stimulated cAMP phosphodiesterases.

PDE2A PDE3A

1.59e-052139212038792
Pubmed

A novel nuclear phosphoprotein, GANP, is up-regulated in centrocytes of the germinal center and associated with MCM3, a protein essential for DNA replication.

MCM3 MCM3AP

1.59e-052139210733502
Pubmed

Pbx1 is required for adult subventricular zone neurogenesis.

PBX1 PBX2

1.59e-052139227226325
Pubmed

Structure, expression, and chromosomal localization of the human gene encoding a germinal center-associated nuclear protein (GANP) that associates with MCM3 involved in the initiation of DNA replication.

MCM3 MCM3AP

1.59e-052139211024281
Pubmed

The MCM3 acetylase MCM3AP inhibits initiation, but not elongation, of DNA replication via interaction with MCM3.

MCM3 MCM3AP

1.59e-052139212226073
Pubmed

Genetic polymorphisms modify the response of factor VII to oral contraceptive use: an example of gene-environment interaction.

F7 FGB

1.59e-052139212616980
Pubmed

A high-throughput approach for measuring temporal changes in the interactome.

ATP6V1E1 PDE3A UBQLN1 MYO1E USP24 MCM3 EIF3CL PPP1CA DHX9 PPP1CC XPO5 UBE3A STIP1 HERC4 SNRNP200 AP3D1 TBCD HTT

2.12e-0514551391822863883
Pubmed

Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.

DNAH17 DNAH8 DNAH11

2.20e-051413939373155
Pubmed

Oocyte-expressed yes-associated protein is a key activator of the early zygotic genome in mouse.

BCL2L10 SLC39A4 CNNM4 ALPP

3.21e-0545139426902285
Pubmed

New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing.

RBM10 ATG2B MCM3 ARHGAP35 NEB DHX9 PPP1CC NBPF14 SNRNP200 SMG6

4.36e-055131391025798074
Pubmed

Topoisomerase 1 inhibitor topotecan delays the disease progression in a mouse model of Huntington's disease.

UBE3A HTT

4.75e-053139228007908
Pubmed

The TALE homeodomain protein Pbx2 is not essential for development and long-term survival.

PBX1 PBX2

4.75e-053139215169896
Pubmed

Mutually exclusive binding of PP1 and RNA to AKAP149 affects the mitochondrial network.

PPP1CA PPP1CC

4.75e-053139219074462
Pubmed

1E7-03, a low MW compound targeting host protein phosphatase-1, inhibits HIV-1 transcription.

PPP1CA PPP1CC

4.75e-053139225073485
Pubmed

The direct binding of the catalytic subunit of protein phosphatase 1 to the PKR protein kinase is necessary but not sufficient for inactivation and disruption of enzyme dimer formation.

PPP1CA PPP1CC

4.75e-053139212138106
Pubmed

Chromosomal localization of human, rat, and mouse protein phosphatase type 1 beta catalytic subunit genes (PPP1CB) by fluorescence in situ hybridization.

PPP1CA PPP1CC

4.75e-05313927857673
Pubmed

Differential regulation of endothelial cell permeability by cGMP via phosphodiesterases 2 and 3.

PDE2A PDE3A

4.75e-053139217704206
Pubmed

Dynamic targeting of protein phosphatase 1 within the nuclei of living mammalian cells.

PPP1CA PPP1CC

4.75e-053139211739654
Pubmed

A novel pbx family member expressed during early zebrafish embryogenesis forms trimeric complexes with Meis3 and Hoxb1b.

PBX1 PBX2

4.75e-053139210679934
Pubmed

Human papillomavirus 16 E6 oncoprotein interferences with insulin signaling pathway by binding to tuberin.

TSC2 UBE3A

4.75e-053139215175323
Pubmed

Characterization of protein phosphatases in mouse oocytes.

PPP1CA PPP1CC

4.75e-05313929882488
Pubmed

Homeodomain proteins MEIS1 and PBXs regulate the lineage-specific transcription of the platelet factor 4 gene.

PBX1 PBX2

4.75e-053139212609849
Pubmed

FEM1A and FEM1B: novel candidate genes for polycystic ovary syndrome.

FEM1C FEM1A

4.75e-053139218757445
Pubmed

Iloprost- and isoproterenol-induced increases in cAMP are regulated by different phosphodiesterases in erythrocytes of both rabbits and humans.

PDE2A PDE3A

4.75e-053139219252089
Pubmed

Association of beta-fibrinogen and factor VII polymorphism with plasma fibrinogen and factor VII levels, and no association of PAI-1 polymorphism with plasma PAI-1 levels in hemodialysis patients.

F7 FGB

4.75e-053139212141403
Pubmed

Protein phosphatase 1 (PP1) is a post-translational regulator of the mammalian circadian clock.

PPP1CA PPP1CC

4.75e-053139221712997
Pubmed

NOM1 targets protein phosphatase I to the nucleolus.

PPP1CA PPP1CC

4.75e-053139217965019
Pubmed

Minichromosome maintenance protein 2 and 3 promote osteosarcoma progression via DHX9 and predict poor patient prognosis.

MCM3 DHX9

4.75e-053139228460433
Pubmed

The Hox cofactor and proto-oncogene Pbx1 is required for maintenance of definitive hematopoiesis in the fetal liver.

PBX1 PBX2

4.75e-053139211468159
Pubmed

Prep1, a novel functional partner of Pbx proteins.

PBX1 PBX2

4.75e-05313929482739
Pubmed

Myr 8, a novel unconventional myosin expressed during brain development associates with the protein phosphatase catalytic subunits 1alpha and 1gamma1.

PPP1CA PPP1CC

4.75e-053139211588169
Pubmed

MCM3-binding GANP DNA-primase is associated with a novel phosphatase component G5PR.

MCM3 MCM3AP

4.75e-053139212167160
Pubmed

Global genetic analysis in mice unveils central role for cilia in congenital heart disease.

IFT140 PDE2A CNTRL MAPK7 DNAH11

5.27e-05100139525807483
Pubmed

Selected reaction monitoring mass spectrometry reveals the dynamics of signaling through the GRB2 adaptor.

PIK3AP1 PPP1CA PPP1CC DNM3 PEAK1

6.06e-05103139521706016
Pubmed

Mapping brain gene coexpression in daytime transcriptomes unveils diurnal molecular networks and deciphers perturbation gene signatures.

CHN1 PPP1CA TRANK1 HTT

6.15e-0553139436265442
Pubmed

A quantitative atlas of mitotic phosphorylation.

RBM10 RNF213 EIF3CL

6.78e-0520139318669648
Pubmed

SLFN11 promotes CDT1 degradation by CUL4 in response to replicative DNA damage, while its absence leads to synthetic lethality with ATR/CHK1 inhibitors.

RBM10 HECTD4 RNF213 CTIF DHX9 XPO5 HELZ

6.95e-05250139733536335
Pubmed

Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells.

ATP6V1E1 RBM10 MCM3 EIF3CL DHX9 PPP1CC UBE3A STIP1 HERC4 SNRNP200 TBCD

7.88e-056651391130457570
Pubmed

Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.

ZC3H14 ARHGAP10 MCF2L2 MCM3 AHCYL2 HEATR1 ARHGAP35 CHN1 FAM13B PLEKHG1 DNM3 STIP1 PEAK1

8.30e-059161391332203420
Pubmed

Dephosphorylation of the RNA sensors RIG-I and MDA5 by the phosphatase PP1 is essential for innate immune signaling.

PPP1CA PPP1CC

9.47e-054139223499489
Pubmed

Nuclear targeting of protein phosphatase-1 by HIV-1 Tat protein.

PPP1CA PPP1CC

9.47e-054139216131488
Pubmed

Identification of the spermatogenic zip protein Spz1 as a putative protein phosphatase-1 (PP1) regulatory protein that specifically binds the PP1cgamma2 splice variant in mouse testis.

PPP1CA PPP1CC

9.47e-054139215226296
Pubmed

Regulation of ENaC in mice lacking renal insulin receptors in the collecting duct.

INSR SCNN1G

9.47e-054139223558339
Pubmed

Nuclear protein phosphatase-1 regulates HIV-1 transcription.

PPP1CA PPP1CC

9.47e-054139212788939
Pubmed

Protein phosphatase 1 inhibits p53 signaling by dephosphorylating and stabilizing Mdmx.

PPP1CA PPP1CC

9.47e-054139223277204
Pubmed

The neuronal actin-binding proteins, neurabin I and neurabin II, recruit specific isoforms of protein phosphatase-1 catalytic subunits.

PPP1CA PPP1CC

9.47e-054139212016225
Pubmed

Inhibitor-2 regulates protein phosphatase-1 complexed with NimA-related kinase to induce centrosome separation.

PPP1CA PPP1CC

9.47e-054139212221103
Pubmed

Regulation of insulin-like growth factor receptors by Ubiquilin1.

UBQLN1 INSR

9.47e-054139229054976
Pubmed

Phosphorylation of protein phosphatase 1 by cyclin-dependent protein kinase 5 during nerve growth factor-induced PC12 cell differentiation.

PPP1CA PPP1CC

9.47e-054139217202132
Pubmed

Synphilin-1A is a phosphoprotein phosphatase 1-interacting protein and affects PPP1 sorting to subcellular compartments.

PPP1CA PPP1CC

9.47e-054139224902662
Pubmed

cDNA characterization and chromosomal mapping of two human homologues of the Drosophila dishevelled polarity gene.

DVL1P1 DVL1

9.47e-05413928817329
Pubmed

Characterization of the neuronal targeting protein spinophilin and its interactions with protein phosphatase-1.

PPP1CA PPP1CC

9.47e-054139210194355
Pubmed

Human dishevelled genes constitute a DHR-containing multigene family.

DVL1P1 DVL1

9.47e-05413929192851
Pubmed

PBX1 acts as terminal selector for olfactory bulb dopaminergic neurons.

PBX1 PBX2

9.47e-054139232156753
Pubmed

Role of the ubiquitin ligase E6AP/UBE3A in controlling levels of the synaptic protein Arc.

SACS UBE3A

9.47e-054139223671107
Pubmed

Non-canonical Wnt signaling induces ubiquitination and degradation of Syndecan4.

DVL1P1 DVL1

9.47e-054139220639201
Pubmed

Combined effect of hemostatic gene polymorphisms and the risk of myocardial infarction in patients with advanced coronary atherosclerosis.

F7 FGB

9.47e-054139218253477
Pubmed

NIMA-related kinase 2 (Nek2), a cell-cycle-regulated protein kinase localized to centrosomes, is complexed to protein phosphatase 1.

PPP1CA PPP1CC

9.47e-054139210880350
Pubmed

Small molecules targeted to a non-catalytic "RVxF" binding site of protein phosphatase-1 inhibit HIV-1.

PPP1CA PPP1CC

9.47e-054139222768081
Pubmed

E6AP AZUL interaction with UBQLN1/2 in cells, condensates, and an AlphaFold-NMR integrated structure.

UBQLN1 UBE3A

9.47e-054139236827983
Pubmed

Interaction of inhibitor-2 with the catalytic subunit of type 1 protein phosphatase. Identification of a sequence analogous to the consensus type 1 protein phosphatase-binding motif.

PPP1CA PPP1CC

9.47e-054139210807923
Pubmed

Pbx/Meis deficiencies demonstrate multigenetic origins of congenital heart disease.

PBX1 PBX2

9.47e-054139218723445
Pubmed

Automated phosphoproteome analysis for cultured cancer cells by two-dimensional nanoLC-MS using a calcined titania/C18 biphasic column.

RNF213 EIF3CL

9.47e-054139218187866
Pubmed

PBX2 and PBX3, new homeobox genes with extensive homology to the human proto-oncogene PBX1.

PBX1 PBX2

9.47e-05413921682799
GeneFamilyDyneins, axonemal

DNAH17 DNAH8 DNAH11

9.35e-0517963536
GeneFamilyRho GTPase activating proteins|BCH domain containing

ARHGAP10 ARHGAP35 CHN1 FAM13B

1.43e-0450964721
GeneFamilyAnkyrin repeat domain containing

ANK3 FEM1C POTEC TRANK1 FEM1A TP53BP2

1.84e-03242966403
GeneFamilyProtein phosphatase catalytic subunits|EF-hand domain containing

PPP1CA PPP1CC

2.09e-0313962693
CoexpressionPARENT_MTOR_SIGNALING_UP

IFT140 RBM10 KLF3 TSC2 KLHL20 DHX9 TRANK1 CATSPER2 CPQ FGB HELZ SLC4A4 ENPEP SERPIND1

1.73e-0656713714M16909
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

ZC3H14 GALNT1 UBL3 RBMS1 RHOBTB3 USP24 APBB2 CTIF FOXN3 ARHGAP35 KLHL20 SACS UBE3A HELZ NBPF14 HERC4 TP53BP2

2.52e-0685613717M4500
CoexpressionGSE7764_IL15_NK_CELL_24H_VS_SPLENOCYTE_DN

INSR AHCYL2 MEFV EVA1B CPQ HERC4 MXI1 WDTC1

1.04e-051991378M5726
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PDE2A PCDH12 CHN1 PLEKHG1 FAR2 RBMS3 DNM3 PBX1 TBCD

9.45e-091911399f663131a4810584c5854bd64ee7991a237b7707f
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PDE2A CHN1 PLEKHG1 FAR2 RBMS3 DNM3 PEAK1 PBX1 TBCD

1.08e-081941399f76808666fb875fc787751cbfd924d9be20a8192
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PDE2A CHN1 PLEKHG1 FAR2 RBMS3 DNM3 PEAK1 PBX1 TBCD

1.08e-081941399a52c5906fce43c2f72cf7e463a3d15cde06431f6
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PDE2A POLB PCDH12 CHN1 FAR2 DNM3 PBX1 TBCD

1.80e-071941398ad6c04ad0621689e3bf4c94ccd6e60653bbd02c7
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PDE2A CHN1 PLEKHG1 FAR2 RBMS3 DNM3 PEAK1 PBX1

1.80e-071941398f5706ab6bc803606c4640ddd606617e4e797ccc9
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PDE2A CHN1 PLEKHG1 FAR2 RBMS3 DNM3 PBX1 TBCD

1.80e-071941398fa6d51f36a3dae8763a595c20892987ed454c0f0
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PDE2A CHN1 PLEKHG1 FAR2 DNM3 PEAK1 PBX1 TBCD

1.94e-071961398ab7be3858deabbd1fc44e8b9da8ff49a50bf1fb1
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PDE2A CHN1 PLEKHG1 FAR2 RBMS3 DNM3 PEAK1 PBX1

2.10e-0719813980a172c6d997c7cfbad34b56e80121bd104dee67d
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell_prolif|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PDE2A GALNT1 POLB FAR2 RBMS3 PBX1 TBCD

1.18e-061721397c056d44e2e130ceccadfcdceb192a7f095d779c8
ToppCellPBMC-Convalescent-Hematopoietic-Platelet-Platelet-plt_1|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

PDE2A PDE3A ACRBP STON2 DNM3 PBX1 SPOCD1

1.60e-0618013973c605d6adb4199963532f3639f2c768f7e575152
ToppCellPBMC-Convalescent-Hematopoietic-Platelet-Platelet-plt_1|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PDE2A PDE3A ACRBP STON2 DNM3 PBX1 SPOCD1

1.60e-0618013973d52ca0568f9c0d6359b302ff5ff41b075f78597
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

BRINP3 ANK3 MYO1E RHOBTB3 MOB1B SCNN1G SLC4A4

1.66e-061811397aa233b652921848af2257cc3687a7a09c3acfb67
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

BRINP3 ANK3 MYO1E CDC42BPB MOB1B SCNN1G SLC4A4

1.92e-061851397a0a629e5d2b65f670ea907bd3f5e3caf17687d8f
ToppCell10x5'-GI_small-bowel-Myeloid_Monocytic-Nonclassical_monocytes|GI_small-bowel / Manually curated celltypes from each tissue

PIK3AP1 ACRBP INSR CDH23 MEFV EVA1B XPO5

1.99e-061861397a16ecf70271894a842925f232009e2623d16947e
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOK6 PDE3A ARHGAP10 CACHD1 RBMS3 ANGPT4 DNAH11

2.06e-061871397ec4b694487cc446999c7b27b119950a4f252c4b3
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOK6 PDE3A ARHGAP10 CACHD1 RBMS3 ANGPT4 DNAH11

2.06e-061871397530e4e6d91b5c0d9aa4543caa2b734a1674c5788
ToppCellremission-Platelet|World / disease stage, cell group and cell class

PDE3A ACRBP MOB1B STON2 DNM3 PBX1 SPOCD1

2.13e-061881397fa69f20ef6b8ce620ba342f0984d40ddf259bc3f
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PDE2A CDH23 CHN1 FAR2 RBMS3 DNM3 TBCD

2.45e-0619213971ee4783051ec94ea94600f040edcb385fc4289f1
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PDE2A CACHD1 CHN1 PLEKHG1 DNM3 PBX1 TBCD

2.45e-061921397c0e59e642b42c055cf73d029cf54d07d9b719359
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PDE2A CACHD1 CHN1 PLEKHG1 DNM3 PBX1 TBCD

2.54e-06193139752e918884877b6659cdca0496390e440f73694a9
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PDE2A CACHD1 PLEKHG1 DNM3 PEAK1 PBX1 TBCD

2.62e-06194139774a9fdb73f279bebb6337510deab9aaaf9f7e957
ToppCell10x5'-blood-Hematopoietic_Erythro-Mega-Megakaryocyte_early|blood / Manually curated celltypes from each tissue

PDE3A ACRBP MOB1B STON2 DNM3 PBX1 SPOCD1

2.62e-06194139763dea7d630962761a70aa88e720ee35c22cbc81a
ToppCell10x5'-blood-Hematopoietic_Erythro-Mega|blood / Manually curated celltypes from each tissue

PDE3A ACRBP MOB1B STON2 DNM3 PBX1 SPOCD1

2.62e-061941397d0e7d35b5086834929c4bd39d4c6719b2d5fc71e
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PDE2A CHN1 PLEKHG1 FAR2 DNM3 PBX1 TBCD

2.62e-061941397b490fffc94f005dff9a34ce34d80ca776e3a1387
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PDE2A CHN1 PLEKHG1 FAR2 RBMS3 DNM3 TBCD

2.81e-0619613978ad8efb631164b46f0c082572270188e5ead20bf
ToppCellCOVID-19-kidney-VWF+PLVAP+VCAM1+EC|kidney / Disease (COVID-19 only), tissue and cell type

PDE2A CHN1 PLEKHG1 FAR2 RBMS3 DNM3 PBX1

2.81e-061961397ac2c4a325efa8497a755cd31fb6a9d94d8e3bf42
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PDE2A CACHD1 CHN1 PLEKHG1 RBMS3 DNM3 PBX1

2.81e-06196139722767bcf0095d9eb0cbed7cdc74e4d32d9357e1b
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PDE2A CHN1 PLEKHG1 FAR2 RBMS3 PBX1 TBCD

2.81e-061961397b8f89a50114932c08fc5daac4b549adfe9df8e66
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PDE2A CHN1 PLEKHG1 FAR2 RBMS3 DNM3 TBCD

2.81e-0619613979606ea7e42f707e69ea891b3521037613b9675f5
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Endothelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PDE2A CACHD1 CHN1 PLEKHG1 RBMS3 DNM3 PBX1

2.81e-061961397adee900dcd16dbaba15c58bdcace09ba20214950
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PDE2A CHN1 PLEKHG1 FAR2 RBMS3 PBX1 TBCD

2.81e-061961397d0ff1082898d2db47c88d2678466514e9e9193d3
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PDE2A INSR CACHD1 CHN1 PLEKHG1 DNM3 PBX1

2.90e-061971397c10dd1aaec01fb662eac83dfde90e3e426665d65
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PDE2A INSR CACHD1 CHN1 PLEKHG1 DNM3 PBX1

2.90e-0619713972844dbcd0a673ed81c99920aa45858651a00736d
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PDE2A CHN1 PLEKHG1 FAR2 RBMS3 DNM3 PBX1

3.00e-06198139707701c73137947ed4a27e225975329235bbb8734
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PDE2A CHN1 PLEKHG1 FAR2 RBMS3 DNM3 PBX1

3.00e-061981397fa84bf8533d1b91d2c2bcf06b710670605072b89
ToppCell(09)_Interm._secr.>cil.-(2)_GFP_FOXI1|(09)_Interm._secr.>cil. / shred by cell type by condition

GALNT1 UBL3 CNTRL INSR KLF3 PBX1 AP3D1

3.10e-061991397fc680f85ebd3bab4c72876a19a461b0afb5f51ce
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Th|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

FAM184A PDE2A SLC39A4 NEB CNNM4 PBX1

1.38e-0516613966a6ed5c7a43fee9a8a9be42dfa99303815b8e8ef
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PDE3A MYO1E RBMS1 MCF2L2 APBB2 RBMS3

1.58e-051701396876b84740e15399bfff2b9c7f0b80fd759bbdb3f
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PDE3A MYO1E RBMS1 MCF2L2 APBB2 RBMS3

1.58e-0517013961f8738acf439d893880db7e1fdc9b3615ca00c39
ToppCell10x5'-lymph-node_spleen-Hematopoietic_Erythro-Mega|lymph-node_spleen / Manually curated celltypes from each tissue

PDE3A ACRBP STON2 DNM3 PBX1 SPOCD1

1.86e-0517513965ca3369ce2c2bb88ba097260195aecd67cec1a3a
ToppCell10x5'-lymph-node_spleen-Hematopoietic_Erythro-Mega-Megakaryocyte_early|lymph-node_spleen / Manually curated celltypes from each tissue

PDE3A ACRBP STON2 DNM3 PBX1 SPOCD1

1.92e-05176139650fe3fd862dd6a6550ebb8c27f337cde468efedc
ToppCell(9)_Platelet|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)

PDE3A ACRBP STON2 DNM3 PBX1 SPOCD1

1.98e-0517713960830944c43de300815831a9e2b2fce40965e7d12
ToppCell(9)_Platelet|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)

PDE3A ACRBP STON2 DNM3 PBX1 SPOCD1

1.98e-051771396e63d01c7fce4fa1256212fa7e95f74281edb3a01
ToppCellPBMC-Convalescent-Hematopoietic-Platelet|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

PDE3A ACRBP STON2 DNM3 PBX1 SPOCD1

2.05e-051781396f5d83ad082e31d5601890d245b9fb4f9ef6a062b
ToppCellPBMC-Convalescent-Hematopoietic-Platelet-Platelet|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

PDE3A ACRBP STON2 DNM3 PBX1 SPOCD1

2.05e-051781396a2a8fc14f492a4695e6991a357b6626145f1bf7f
ToppCellPBMC-Convalescent-Hematopoietic-Platelet-Platelet|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PDE3A ACRBP STON2 DNM3 PBX1 SPOCD1

2.11e-051791396510927794bbd21814eba75286e0801eb1fd2e8a6
ToppCellPBMC-Convalescent-Hematopoietic|Convalescent / Location, Disease Group, Cell group, Cell class (2021.03.09)

PDE3A ACRBP STON2 DNM3 PBX1 SPOCD1

2.11e-0517913963b1616e974ea7792ff5c37da3b0281f28edfbb56
ToppCellPBMC-Convalescent-Hematopoietic|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PDE3A ACRBP STON2 DNM3 PBX1 SPOCD1

2.11e-05179139635271a4396a533f6d960ce55d171a32d9d2fd1a4
ToppCellPBMC-Convalescent-Hematopoietic-Platelet|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PDE3A ACRBP STON2 DNM3 PBX1 SPOCD1

2.11e-051791396906a5ebbbac660b6fd498ced09d0ada40a3e64af
ToppCellCOVID-19_Convalescent-Hematopoietic_Mega-Platelet|COVID-19_Convalescent / Disease group, lineage and cell class

PDE3A ACRBP STON2 DNM3 PBX1 SPOCD1

2.18e-051801396deed53167504c91220b35a63366ed7d8f02a5254
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CABP1 ONECUT2 BRINP3 ARHGAP10 CHN1 ENPEP

2.18e-0518013965391d23817f5cc88a0871ddb98968897c839f464
ToppCellCOVID-19_Convalescent-Hematopoietic_Mega|COVID-19_Convalescent / Disease group, lineage and cell class

PDE3A ACRBP STON2 DNM3 PBX1 SPOCD1

2.18e-05180139617323d382ae322e388e230fdad13e3464ea73e8e
ToppCellInfluenza_Severe-Platelet|Influenza_Severe / Disease group and Cell class

PDE3A ACRBP STON2 DNM3 PBX1 SPOCD1

2.25e-0518113964d037b098bb6f780ed8b15c0ec23a6f4d86bf45a
ToppCellremission-Platelet|remission / disease stage, cell group and cell class

PDE3A ACRBP STON2 DNM3 PBX1 SPOCD1

2.32e-05182139665e2798aacd670cbc3a8c8e9d1a2f7768513bb70
ToppCell10x5'-bone_marrow-Hematopoietic_Erythro-Mega-Megakaryocyte_early|bone_marrow / Manually curated celltypes from each tissue

PDE3A ACRBP STON2 DNM3 PBX1 SPOCD1

2.39e-0518313963cc9f3dc3bc4bde1d3408b0a6ba58e135a11036d
ToppCellCOVID-19-Heart-EC_3|COVID-19 / Disease (COVID-19 only), tissue and cell type

CABP1 APBB2 CHN1 PLEKHG1 DNM3 TBCD

2.39e-051831396ff95382cfed592190d0636d2b750328471f82e0d
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PDE2A CHN1 PLEKHG1 FAR2 DNM3 PBX1

2.47e-051841396688428103e8b19f45f2f65d70a0f30c904c8411c
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CABP1 ONECUT2 BRINP3 ARHGAP10 CHN1 ENPEP

2.47e-0518413966475a43201b136dcc9b113d2ca4cfa154ed9d65d
ToppCellcontrol-Others-Megakaryocytes|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

PDE3A ACRBP STON2 DNM3 PBX1 SPOCD1

2.47e-051841396213915f2889ce8ecbe5f7b19bc2b24ed8c5efe1d
ToppCellmegakaryocytic|World / Lineage and Cell class

PDE3A ACRBP STON2 DNM3 PBX1 SPOCD1

2.47e-051841396b1c630ca2189d9d49402a5621b57618976fbea5c
ToppCellCOVID-19-Endothelial_cells-Systemic_venous_endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

PDE2A MYO1E CACHD1 CHN1 PLEKHG1 DNM3

2.54e-051851396f5e14181f45c37d13ee9e017a4c8bc248c353676
ToppCellPBMC-Control-Hematopoietic-Platelet-Platelet-plt_1|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PDE3A ACRBP STON2 DNM3 PBX1 SPOCD1

2.62e-051861396107bc473f5e57238390f8e0ab9f7263a8f93948c
ToppCellPBMC-Control-Hematopoietic-Platelet-Platelet-plt_1|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

PDE3A ACRBP STON2 DNM3 PBX1 SPOCD1

2.62e-05186139613a9ddcf93b0c4319ab9d484af5e2056e9754caa
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PDE2A PCDH12 CHN1 PLEKHG1 DNM3 TBCD

2.70e-05187139635c382c0aabd46906113e5db30ea24bb8e658899
ToppCellControl-Fibroblasts-Other_FB|Control / group, cell type (main and fine annotations)

DOK6 BRINP3 PDE3A ARHGAP10 CHN1 RBMS3

2.70e-051871396bd3739c4a52aa1ba5deffd778e113a9800f7e158
ToppCellT_cells-ISG-high_CD4+_T_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

FAM184A ANK3 RNF213 TRANK1 FAR2 MASTL

2.78e-0518813966f8946d4710f6e32c937213f99b790b098b8819c
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

BRINP3 ANK3 AHCYL2 MOB1B SCNN1G SLC4A4

2.78e-05188139658ccb31cdf43167872ef0fc737e6f9c51ee2e060
ToppCellCOVID-19-kidney-VWF+PLVAP+VCAM1+EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

PDE2A INSR CHN1 PLEKHG1 DNM3 PBX1

2.87e-051891396c121817ddad164e9cfe382c43d0cbc9215508d02
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

BRINP3 ANK3 MYO1E MOB1B SCNN1G SLC4A4

2.87e-051891396fc88c51ace7d883c01617f3f9b5fab70cc91cc09
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PDE2A CHN1 PLEKHG1 FAR2 DNM3 PBX1

2.95e-051901396656483751e4bf137e4e4bfb2a03a478a8f7fcb63
ToppCellnucseq-Mesenchymal-Myocytic-Myocytic_1-Pericyte|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

DOK6 PDE3A ARHGAP10 APBB2 CHN1 RBMS3

2.95e-0519013964eb92aef1ee868f4537483d19014d947b7684612
ToppCellMegakaryocytic-erythropoietic-Megakaryo-cells|World / Lineage, cell class and subclass

PDE3A ACRBP STON2 DNM3 PBX1 SPOCD1

2.95e-05190139672b61a12ccea506272ce9cef9051aa2612e6ce57
ToppCellCOVID-19-Heart-EC_3|Heart / Disease (COVID-19 only), tissue and cell type

APBB2 CACHD1 CHN1 PLEKHG1 DNM3 TBCD

2.95e-05190139678e7c502b0450c0b37652b1896a2a752fd8a2111
ToppCellnucseq-Mesenchymal-Myocytic-Myocytic_1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

DOK6 PDE3A ARHGAP10 APBB2 CHN1 RBMS3

2.95e-0519013967be4341e2909101d756f14031c21e705eb45e69a
ToppCelldroplet-Lung-immune-endo-depleted-3m-Mesenchymal-fibroblast_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COLQ CPQ RBMS3 FHOD1 PBX1 ENPEP

3.04e-051911396a261f0738d974784bbdd60f23092bfbcca464459
ToppCellLAM-Epithelial-AT1|Epithelial / Condition, Lineage and Cell class

UBL3 RHOBTB3 APBB2 RBMS3 PEAK1 ALPP

3.04e-0519113963457e15d1e9b36a78363d46b320c4ec46b40290a
ToppCelldroplet-Lung-immune-endo-depleted-3m-Mesenchymal-Alveolar_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COLQ CPQ RBMS3 FHOD1 PBX1 ENPEP

3.04e-0519113966594398cc8151c73696391a43ac110c10283dab1
ToppCell10x3'2.3-week_17-19-Hematopoietic-MK-early_MK|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

DOK6 PDE3A SLC39A4 EVA1B DNM3 PBX1

3.04e-0519113963839bf57419d3ec3d4464277bb33301d2b7d701f
ToppCellCOVID-19-kidney-VWF+PLVAP+EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

PDE2A INSR PCDH12 PLEKHG1 DNM3 TBCD

3.04e-0519113962f00d0b7b2ffce8eb3eb5bbae49a0d425b23c982
ToppCellPBMC-Severe-Hematopoietic-Platelet-Platelet-plt_0|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ACRBP MOB1B STON2 DNM3 PBX1 SPOCD1

3.13e-0519213965bf420b03c32d7bbc919616bcb7d69f3e3a459ed
ToppCellCOVID-19-kidney-AQP1+PLVAP+EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

PDE2A INSR CHN1 PLEKHG1 DNM3 PBX1

3.13e-05192139627ff3621e177e7932dd44dd6baa81551ea75a874
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DOK6 BRINP3 CHN1 PLEKHG1 SLC4A4 PBX1

3.13e-05192139672881b280a415e65f87a80ca1369cbb0b722a0c4
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

MYO1E PPRC1 RBMS1 FGB PEAK1 LONRF3

3.13e-0519213968b86db2ebe0199fee0e9800566a619a24bfdeed5
ToppCellPBMC-Severe-Hematopoietic-Platelet-Platelet-plt_0|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ACRBP MOB1B STON2 DNM3 PBX1 SPOCD1

3.13e-05192139697975340f9ab3ab6e0aa7751b10e008ff3d21bf2
ToppCellCOVID-19-Fibroblasts-Other_FB|COVID-19 / group, cell type (main and fine annotations)

DOK6 BRINP3 APBB2 CHN1 RBMS3 PBX1

3.22e-051931396e6b75be08e33c1de079fb5c02f0b4468128b369c
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PDE2A RBMS1 FAR2 RBMS3 DNM3 PBX1

3.22e-051931396456aa8a8f1f9cbba0bd618a5f623909079c0f56b
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PDE2A INSR PCDH12 CHN1 PLEKHG1 PBX1

3.22e-0519313961f978e102a029a6beb10913052cd0a20c7253e8e
ToppCell10x_3'_v3-blood_(10x_3'_v3)-hematologic-thrombocytic|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

PDE3A ACRBP STON2 DNM3 PBX1 SPOCD1

3.32e-0519413967c38ead538695db1fb1c329ff67d2874aa83c8d2
ToppCellLPS_only-Endothelial|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYO1E APBB2 CACHD1 PCDH12 CHN1 PLEKHG1

3.32e-05194139658f069efdefa0366033764446b9d6ffd4a17807e
ToppCellPND07-28-samps-Mesenchymal|PND07-28-samps / Age Group, Lineage, Cell class and subclass

RHOBTB3 CPQ RBMS3 PEAK1 PBX1 ENPEP

3.32e-05194139668bcc1fe8dc8d5f23a12154fc9b41362fdef0b1d
ToppCell10x_3'_v3-blood_(10x_3'_v3)-hematologic-thrombocytic-platelet|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

PDE3A ACRBP STON2 DNM3 PBX1 SPOCD1

3.32e-0519413964531639974e363a6ff7ea688325a11407c3efd87
ToppCellLPS_only-Endothelial-Endothelial|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYO1E APBB2 CACHD1 PCDH12 CHN1 PLEKHG1

3.32e-051941396bfd92ec75facb0ba55c31e5f2e089d983b3d0169
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PDE2A CHN1 PLEKHG1 FAR2 DNM3 PBX1

3.32e-051941396e55dc30e200c9f576804acb642175eb4fa9146b5
ToppCellCOVID-19-kidney-PLVAP+EC|kidney / Disease (COVID-19 only), tissue and cell type

PDE2A INSR PCDH12 PLEKHG1 RBMS3 TBCD

3.42e-051951396a436483fec137584611f86b7a498a4dc2aa19cd3
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EVA1B RBMS3 FHOD1 PEAK1 PBX1 ENPEP

3.42e-051951396598b69032a8441a23749b27863d80f7a1fc82a96
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PDE2A PCDH12 FAR2 RBMS3 DNM3 PBX1

3.42e-05195139623ced69fd904f1d4114b1a7f99f4b5f65ea8824b
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CABP1 BRINP3 PDE3A ARHGAP10 CHN1 SCAI

3.42e-051951396787e95fb59c40bba784544b662fac37606ae1427
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PDE2A CHN1 PLEKHG1 FAR2 DNM3 PBX1

3.52e-051961396023312af38f816a44b407e0daa32590d953caf99
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PDE2A CHN1 PLEKHG1 FAR2 RBMS3 TBCD

3.52e-051961396145fcf73deba9638b391a1af6c39fa205dc9829f
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PDE2A INSR CACHD1 CHN1 PLEKHG1 PBX1

3.52e-051961396e224338490691d92c1f70b57112fabdcc92b06a9
DrugMerbromin [129-16-8]; Down 200; 5uM; HL60; HT_HG-U133A

MYO1E MYOZ3 CTIF PCDH12 COLQ CRYGC EVA1B FGB MAPK7 WDTC1

3.17e-07199135102577_DN
DrugMegestrol acetate [595-33-5]; Up 200; 10.4uM; HL60; HT_HG-U133A

ONECUT2 IFT140 ANK3 TRANK1 UBE3A MCM3AP DNAH17 FGB ENPEP

2.54e-0619513593091_UP
DrugHomatropine hydrobromide (R,S) [51-56-9]; Down 200; 11.2uM; MCF7; HT_HG-U133A

FAM184A ANK3 MYO1E ARHGAP35 FHOD1 DNAH17 LONRF3 MAPK7 WDTC1

2.65e-0619613591684_DN
DrugAcetylsalicylsalicylic acid [530-75-6]; Up 200; 13.4uM; PC3; HT_HG-U133A

IFT140 SCN11A ANK3 MFSD6 MYOZ3 KLF3 CTIF PCDH12 SLC4A4

2.77e-0619713592061_UP
DrugEthisterone [434-03-7]; Down 200; 12.8uM; MCF7; HT_HG-U133A

ONECUT2 IFT140 SCN11A ANK3 CTIF ARHGAP35 NEB MAPK7 WDTC1

2.77e-0619713592326_DN
Drug2bub

SERPINA4 SALL1 FGB PBX1 PBX2

3.79e-06401355CID005494422
Drugwortmannin from Penicillium funiculosum; Up 200; 0.01uM; MCF7; HT_HG-U133A_EA

CNTRL KLF3 CTIF FOXN3 ARHGAP35 MAPK7 MXI1 WDTC1

1.69e-0518813581023_UP
DrugTolazamide [1156-19-0]; Up 200; 12.8uM; HL60; HT_HG-U133A

CABP1 PDE2A ANK3 KLF3 NEB COLQ FGB MAPK7

2.04e-0519313582482_UP
DrugClenbuterol hydrochloride [21898-19-1]; Down 200; 12.8uM; PC3; HT_HG-U133A

IFT140 ANK3 ARHGAP10 MYOZ3 ARHGAP35 PCDH12 DNM3 TBCD

2.04e-0519313584671_DN
DrugChicago sky blue 6B [2610-05-1]; Down 200; 4uM; PC3; HT_HG-U133A

ONECUT2 ARHGAP10 MYOZ3 CTIF KLHL20 MAPK7 SMG6 WDTC1

2.20e-0519513586626_DN
DrugSulfinpyrazone [57-96-5]; Down 200; 9.8uM; MCF7; HT_HG-U133A

ONECUT2 IFT140 CNTRL CTIF ARHGAP35 EVA1B ENPEP WDTC1

2.28e-0519613583192_DN
DrugEstropipate [7280-37-7]; Up 200; 9.2uM; MCF7; HT_HG-U133A

SCN11A MFSD6 DGKQ FOXN3 CPQ ANGPT4 ZNF197 SMG6

2.36e-0519713586068_UP
DrugAminohippuric acid [61-78-9]; Up 200; 20.6uM; HL60; HT_HG-U133A

IFT140 BCL2L10 APBB2 CTIF F7 MCM3AP SNRNP200 WDTC1

2.36e-0519713583076_UP
DrugCephapirin sodium salt [24356-60-3]; Down 200; 9uM; HL60; HT_HG-U133A

IFT140 FAM184A RHOBTB3 KLF3 CTIF ARHGAP35 NEB TBCD

2.45e-0519813582730_DN
DrugMethimazole [60-56-0]; Down 200; 35uM; HL60; HT_HG-U133A

ANK3 MYOZ3 CTIF PCDH12 CRYGC FGB MAPK7 SLC4A4

2.45e-0519813582570_DN
DrugPyridoxine hydrochloride [58-56-0]; Up 200; 19.4uM; MCF7; HT_HG-U133A

IFT140 APBB2 DGKQ ARHGAP35 PCDH12 NEB ENPEP WDTC1

2.54e-0519913587171_UP
DrugGliclazide [21187-98-4]; Up 200; 12.4uM; MCF7; HT_HG-U133A

SCN11A BCL2L10 CTIF KLHL20 CPQ DNM3 PEAK1 WDTC1

2.54e-0519913582870_UP
DrugTheobromine [83-67-0]; Up 200; 22.2uM; HL60; HT_HG-U133A

MYOZ3 DGKQ ARHGAP35 F7 TRANK1 PEAK1 TBCD SMG6

2.54e-0519913582995_UP
DrugOxalamine citrate salt [1949-20-8]; Down 200; 9.2uM; PC3; HT_HG-U133A

SCN11A FAM184A INSR APBB2 CTIF BAHD1 DNAH17 MAPK7

2.54e-0519913586624_DN
DrugBenzylpenicillin sodium [69-57-8]; Up 200; 11.2uM; MCF7; HT_HG-U133A

BCL2L10 CTIF AHCYL2 NEB ZNF197 FGB SLC4A4 WDTC1

2.63e-0520013586839_UP
DrugCDK2 Inhibitor II

POLB MYOZ3 SCNN1G SMG6 WDTC1

4.22e-05651355CID005858639
DrugT-C-T

INSR SALL1 SACS FGB SERPIND1 ALPP

5.84e-051131356CID000447409
Drugwortmannin; Up 200; 1uM; MCF7; HT_HG-U133A_EA

ANK3 MYO1E CNTRL INSR ATG2B FAM13B MXI1

8.52e-051751357869_UP
DrugHexetidine [141-94-6]; Up 200; 11.8uM; HL60; HT_HG-U133A

IFT140 BCL2L10 INSR KLF3 DNAH17 SNRNP200 SENP7

1.20e-0418513572457_UP
DrugGly-pro-arg-pro

SALL1 FGB MLN SERPIND1

1.22e-04431354CID000123681
DrugSR-202

PPRC1 INSR MAPK7

1.30e-04171353CID000060910
DrugAmpyrone [83-07-8]; Down 200; 19.6uM; PC3; HT_HG-U133A

ANK3 APBB2 AHCYL2 DHX9 CNNM4 SLC4A4 HERC4

1.42e-0419013574507_DN
DrugYohimbinic acid monohydrate [27801-27-2]; Up 200; 11.2uM; PC3; HT_HG-U133A

ONECUT2 SCN11A RHOBTB3 MCF2L2 RBMS3 PBX1 SNRNP200

1.62e-0419413574082_UP
DrugL(-)-vesamicol hydrochloride [112709-59-8]; Up 200; 13.6uM; PC3; HT_HG-U133A

CABP1 ONECUT2 CTIF ARHGAP35 FGB PEAK1 SLC4A4

1.62e-0419413575056_UP
Drug(-)-Isoproterenol hydrochloride [5984-95-2]; Up 200; 16.2uM; MCF7; HT_HG-U133A

ONECUT2 BCL2L10 MYOZ3 CTIF CPQ PEAK1 SLC4A4

1.62e-0419413576833_UP
DrugMebendazole [31431-39-7]; Down 200; 13.6uM; PC3; HT_HG-U133A

FAM184A MFSD6 APBB2 AHCYL2 CATSPER2 ZNF197 LONRF3

1.62e-0419413573671_DN
Drug(R)-Propranolol hydrochloride [13071-11-9]; Up 200; 13.6uM; MCF7; HT_HG-U133A

CTIF AHCYL2 PCDH12 NEB CRYGC EVA1B FGB

1.67e-0419513573553_UP
DrugFluocinonide [356-12-7]; Up 200; 8uM; PC3; HT_HG-U133A

CABP1 APBB2 KLF3 UBE3A DNAH17 MLN ALPP

1.67e-0419513573757_UP
DrugPicrotoxinin [17617-45-7]; Down 200; 13.6uM; PC3; HT_HG-U133A

FAM184A ARHGAP10 APBB2 ARHGAP35 DNM3 TBCD WDTC1

1.67e-0419513574260_DN
DrugLansoprazole [103577-45-3]; Up 200; 10.8uM; MCF7; HT_HG-U133A

ARHGAP10 APBB2 CTIF FOXN3 NEB KLHL20 DNAH17

1.67e-0419513573529_UP
DrugProadifen hydrochloride [62-68-0]; Down 200; 10.2uM; HL60; HT_HG-U133A

IFT140 KLF3 CTIF COLQ CRYGC CPQ AP3D1

1.67e-0419513572707_DN
Drugrotenone; Up 200; 1uM; MCF7; HT_HG-U133A

MYO1E CTIF ARHGAP35 CPQ ZNF197 DNM3 WDTC1

1.67e-0419513575943_UP
DrugFluvoxamine maleate [61718-82-9]; Up 200; 9.2uM; HL60; HT_HG-U133A

IFT140 PDE2A ANK3 BCL2L10 APBB2 DNM3 WDTC1

1.72e-0419613572913_UP
Drugalpha-estradiol; Up 200; 0.01uM; HL60; HT_HG-U133A

ONECUT2 SCN11A ANK3 F7 CNNM4 ENPEP SMG6

1.72e-0419613572670_UP
Drug(-)-Cinchonidine [485-71-2]; Up 200; 13.6uM; PC3; HT_HG-U133A

IFT140 SCN11A INSR REL ARHGAP35 NEB SLC4A4

1.72e-0419613575833_UP
DrugBenoxinate hydrochloride [5987-82-6]; Up 200; 11.6uM; PC3; HT_HG-U133A

CABP1 ONECUT2 IFT140 RHOBTB3 ARHGAP35 FGB SLC4A4

1.72e-0419613573996_UP
DrugTerconazole [67915-31-5]; Down 200; 7.6uM; MCF7; HT_HG-U133A

ONECUT2 APBB2 AHCYL2 ARHGAP35 CPQ MAPK7 SLC4A4

1.72e-0419613574407_DN
DrugPentetic acid [67-43-6]; Down 200; 10.2uM; HL60; HT_HG-U133A

FAM184A APBB2 AHCYL2 ARHGAP35 NEB EVA1B ENPEP

1.72e-0419613573049_DN
DrugPHA-00767505E [723337-45-9]; Down 200; 10uM; PC3; HT_HG-U133A

ONECUT2 CTIF ARHGAP35 DNM3 MLN SLC4A4 TBCD

1.78e-0419713576545_DN
DrugPentylenetetrazole [54-95-5]; Up 200; 29uM; HL60; HG-U133A

APBB2 KLF3 DENND2D ARHGAP35 FAM13B DHX9 SERPINA4

1.78e-0419713571408_UP
DrugKawain [500-64-1]; Down 200; 17.4uM; MCF7; HT_HG-U133A

IFT140 INSR APBB2 CTIF FEM1C MAPK7 ENPEP

1.78e-0419713574693_DN
DrugCP-319743 [172078-87-4]; Down 200; 10uM; MCF7; HT_HG-U133A

ONECUT2 APBB2 CTIF AHCYL2 EVA1B LONRF3 MAPK7

1.78e-0419713577486_DN
DrugPyrilamine maleate [59-33-6]; Up 200; 10uM; MCF7; HT_HG-U133A

SCN11A BCL2L10 DGKQ ARHGAP35 CATSPER2 UBE3A FGB

1.78e-0419713577223_UP
DrugIoversol [87771-40-2]; Up 200; 5uM; PC3; HT_HG-U133A

CABP1 INSR FOXN3 NEB FGB SLC4A4 SENP7

1.78e-0419713576726_UP
DrugKhellin [82-02-0]; Down 200; 15.4uM; PC3; HT_HG-U133A

CTIF ARHGAP35 NEB F7 DNAH17 ZNF197 FGB

1.83e-0419813576641_DN
DrugIdazoxan hydrochloride [79944-56-2]; Down 200; 16.6uM; HL60; HT_HG-U133A

MYO1E RHOBTB3 KLF3 COLQ DNM3 MAPK7 WDTC1

1.83e-0419813573088_DN
DrugIopamidol [60166-93-0]; Up 200; 5.2uM; HL60; HT_HG-U133A

RHOBTB3 ARHGAP35 F7 EVA1B DNAH17 MLN SNRNP200

1.83e-0419813572732_UP
Drugalpha-estradiol; Up 200; 0.01uM; MCF7; HG-U133A

ZC3H14 CNTRL ATG2B USP24 APBB2 CDC42BPB AP3D1

1.83e-041981357762_UP
DrugHyoscyamine (L) [101-31-5]; Down 200; 13.8uM; PC3; HT_HG-U133A

FAM184A ARHGAP10 KLHL20 RBMS3 SLC4A4 TBCD WDTC1

1.83e-0419813575099_DN
DrugCinnarizine [298-57-7]; Down 200; 10.8uM; MCF7; HT_HG-U133A

IFT140 CNTRL APBB2 CDC42BPB EVA1B HELZ MAPK7

1.83e-0419813573175_DN
Drug15(S)-15-methyl Prostaglandin E2; Down 200; 10uM; MCF7; HT_HG-U133A

ONECUT2 MFSD6 APBB2 CTIF AHCYL2 CATSPER2 MAPK7

1.83e-0419813577489_DN
DrugKynurenine, 3-hydroxy (R,S) [2147-61-7]; Down 200; 17.8uM; PC3; HT_HG-U133A

IFT140 FAM184A MYOZ3 KLF3 CTIF ARHGAP35 SLC4A4

1.83e-0419813574681_DN
DrugFuraltadone hydrochloride [3759-92-0]; Up 200; 11uM; HL60; HT_HG-U133A

ANK3 APBB2 KLF3 AHCYL2 KLHL20 CPQ ANGPT4

1.83e-0419813572554_UP
DrugPentamidine isethionate [140-64-7]; Up 200; 6.8uM; HL60; HT_HG-U133A

MYOZ3 KLF3 ARHGAP35 NEB CHN1 COLQ CNNM4

1.83e-0419813572473_UP
DrugDantrolene sodium salt [14663-23-1]; Up 200; 11.8uM; PC3; HT_HG-U133A

ONECUT2 DENND2D ARHGAP35 DHX9 PBX1 HERC4 AP3D1

1.83e-0419813574343_UP
DrugRolipram [61413-54-5]; Down 200; 14.6uM; HL60; HT_HG-U133A

KLF3 CTIF FOXN3 COLQ EVA1B DNM3 WDTC1

1.83e-0419813573072_DN
DrugBenoxinate hydrochloride [5987-82-6]; Up 200; 11.6uM; MCF7; HT_HG-U133A

ARHGAP10 RBM10 NEB KLHL20 EVA1B PEAK1 SLC4A4

1.83e-0419813571476_UP
Drug2-propylpentanoic acid; Up 200; 1000uM; HL60; HT_HG-U133A

ANK3 RHOBTB3 APBB2 KLF3 PCDH12 RBMS3 UBE3A

1.83e-0419813576168_UP
DrugTiratricol, 3,3',5-triiodothyroacetic acid [51-24-1]; Up 200; 6.4uM; MCF7; HT_HG-U133A

CABP1 ONECUT2 APBB2 AHCYL2 ARHGAP35 NEB ENPEP

1.83e-0419813577011_UP
DrugPhenacetin [62-44-2]; Up 200; 22.4uM; HL60; HT_HG-U133A

MYO1E MYOZ3 KLF3 CTIF COLQ MCM3AP MLN

1.89e-0419913572471_UP
DrugPiretanide [55837-27-9]; Down 200; 11uM; PC3; HT_HG-U133A

ARHGAP10 CRYGC TRANK1 CATSPER2 ZNF197 DNM3 SLC4A4

1.89e-0419913574490_DN
Drugcox-2 inhibitor I; Down 200; 10uM; MCF7; HG-U133A

ZC3H14 ARHGAP10 APBB2 CTIF SERPINA4 EVA1B MLN

1.89e-041991357207_DN
DrugLaudanosine (R,S) [1699-51-0]; Down 200; 11.2uM; MCF7; HT_HG-U133A

IFT140 ARHGAP10 KLF3 FOXN3 KLHL20 PBX1 AP3D1

1.89e-0419913577030_DN
Drugsemustine; Down 200; 100uM; MCF7; HT_HG-U133A

ONECUT2 CNTRL MFSD6 CTIF EVA1B LONRF3 SLC4A4

1.89e-0419913577487_DN
DrugCytisine (-) [485-35-8]; Up 200; 21uM; MCF7; HT_HG-U133A

BCL2L10 CNTRL INSR DGKQ FOXN3 NEB MCM3AP

1.89e-0419913576217_UP
DrugTiabendazole [148-79-8]; Up 200; 19.8uM; PC3; HT_HG-U133A

CNTRL INSR APBB2 MYOZ3 AHCYL2 ARHGAP35 TRANK1

1.95e-0420013574579_UP
DrugPirlindole mesylate [60762-57-4]; Up 200; 12.4uM; MCF7; HT_HG-U133A

IFT140 PDE2A CNTRL CRYGC MCM3AP HERC4 AP3D1

1.95e-0420013575497_UP
DrugTofisopam

PDE2A PDE3A

2.08e-0441352DB08811
Drugmethiin

SERPINA4 SACS

2.08e-0441352CID000082142
DiseaseCiliopathies

CDH23 TSC2 SCNN1G DNAH8 DNAH11

1.55e-041101355C4277690
DiseaseDiGeorge syndrome (is_implicated_in)

DVL1P1 DVL1

2.06e-0451352DOID:11198 (is_implicated_in)
Diseaseneurodegenerative disease (implicated_via_orthology)

DVL1P1 UBQLN1 DVL1 SCNN1G HTT

5.55e-041451355DOID:1289 (implicated_via_orthology)
Diseasemean platelet volume

MYO1E KLF3 MCM3 DENND2D CDC42BPB TRANK1 FAR2 DNM3 STIP1 PBX1 TBCD HTT CDK4

8.36e-04102013513EFO_0004584
Diseasecerebral cavernous malformation (implicated_via_orthology)

RNF213 CDC42BPB

1.11e-03111352DOID:0060669 (implicated_via_orthology)
Diseaseprogression free survival, urinary bladder cancer

DOK6 IFT140

1.33e-03121352EFO_0004920, MONDO_0001187
Diseasetype 2 diabetes mellitus (implicated_via_orthology)

INSR F7 PPP1CA PPP1CC

1.40e-031051354DOID:9352 (implicated_via_orthology)
DiseaseAntihypertensive use measurement

MFSD6 INSR MCM3 PLEKHG1 ENPEP SMG6

1.42e-032651356EFO_0009927
Diseasewaist-hip ratio

ANK3 RBMS1 INSR HECTD4 DGKQ MEFV MEP1A DNAH17 DNM3 PBX1 AP3D1 HTT SCAI SMG6

1.51e-03122613514EFO_0004343
Diseasebreast cancer (is_marker_for)

INSR REL TSC2 F7 CDK4

1.65e-031851355DOID:1612 (is_marker_for)
Diseasefree androgen index

PDE2A ARHGAP10 INSR FOXN3 DENND2D CATSPER2 RBMS3

1.72e-033741357EFO_0007005
Diseasereceptive language perception, parental genotype effect measurement

PLEKHG1 SCNN1G

1.82e-03141352EFO_0005686, EFO_0005939
DiseaseDrug habituation

FAM184A INSR PBX1 DNAH8

1.96e-031151354C0013170
DiseaseDrug abuse

FAM184A INSR PBX1 DNAH8

1.96e-031151354C0013146
DiseasePrescription Drug Abuse

FAM184A INSR PBX1 DNAH8

1.96e-031151354C4316881
DiseaseSubstance-Related Disorders

FAM184A INSR PBX1 DNAH8

1.96e-031151354C0236969
DiseaseDrug Use Disorders

FAM184A INSR PBX1 DNAH8

1.96e-031151354C0013222
DiseaseDrug Dependence

FAM184A INSR PBX1 DNAH8

1.96e-031151354C1510472
DiseaseSubstance Dependence

FAM184A INSR PBX1 DNAH8

1.96e-031151354C0038580
DiseaseSubstance Use Disorders

FAM184A INSR PBX1 DNAH8

1.96e-031151354C0038586
DiseaseOrganic Mental Disorders, Substance-Induced

FAM184A INSR PBX1 DNAH8

1.96e-031151354C0029231
DiseaseSubstance abuse problem

FAM184A INSR PBX1 DNAH8

2.02e-031161354C0740858
DiseaseIschemic stroke, tissue plasminogen activator measurement

HECTD4 FGB

2.10e-03151352EFO_0004791, HP_0002140
DiseaseIschemic stroke, plasminogen activator inhibitor 1 measurement

HECTD4 FGB

2.39e-03161352EFO_0004792, HP_0002140
Diseasemultiple myeloma (is_implicated_in)

BCL2L10 MEFV XPO5

2.53e-03591353DOID:9538 (is_implicated_in)
Diseasefactor XI measurement, Ischemic stroke

HECTD4 FGB

2.70e-03171352EFO_0004694, HP_0002140
Diseasesystolic blood pressure, alcohol drinking

PDE3A INSR HECTD4 PLEKHG1

2.89e-031281354EFO_0004329, EFO_0006335
Diseaselymphocyte count

PIK3AP1 RBMS1 HECTD4 CDH23 KLF3 PPP1CC TAF8 MCM3AP DNAH17 HELZ STIP1 PBX1 AP3D1 HTT SMG6

2.92e-03146413515EFO_0004587
Diseasemigraine disorder, systolic blood pressure

RNF213 SMG6

3.03e-03181352EFO_0006335, MONDO_0005277
Diseasetransitional cell carcinoma (is_marker_for)

REL XPO5 CDK4

3.04e-03631353DOID:2671 (is_marker_for)
Diseaseserum gamma-glutamyl transferase measurement

PIK3AP1 CABP1 ARHGAP10 HECTD4 ARHGAP35 CDC42BPB TRANK1 SALL1 CATSPER2 RBMS3 MXI1

3.26e-0391413511EFO_0004532
Diseasecerebral infarction (is_marker_for)

BRINP3 F7

3.38e-03191352DOID:3526 (is_marker_for)
Diseasecup-to-disc ratio measurement

ANK3 ARHGAP35 SALL1 RBMS3 HELZ HERC4 MXI1

3.73e-034301357EFO_0006939
DiseaseIschemic stroke

PDE3A GALNT1 FOXN3 FGB ENPEP DNAH11

3.85e-033241356HP_0002140
Diseaseinsomnia measurement

PDE2A BRINP3 ARHGAP10 MFSD6 SALL1 MLN DNAH11

4.38e-034431357EFO_0007876
Diseaseprogranulin measurement

UBQLN1 CDH23

4.52e-03221352EFO_0004625
DiseaseBronchiectasis

SCNN1G DNAH11

4.52e-03221352C0006267
Diseasebody weight loss

FOXN3 SALL1

4.52e-03221352EFO_0005245

Protein segments in the cluster

PeptideGeneStartEntry
EDHSQMRQMELEIRP

SMG6

1231

Q86US8
CPSMDIQAMEENLLR

BRINP3

291

Q76B58
MEPDEQLRNDHMNLR

CNTRL

416

Q7Z7A1
ARAIMEEVMSLLQPL

CPQ

381

Q9Y646
NDMLSLVDPMDRSVL

APBB2

476

Q92870
ELAPAELEMLSRSLM

CCDC88B

196

A6NC98
ENLPGLMEMDQDDRV

CATSPER2

476

Q96P56
TGRLLEEQLPEMMTE

CTIF

531

O43310
EEQLPEMMTELLASA

CTIF

536

O43310
MVDQLRERTTMADPL

BCL2L10

1

Q9HD36
ESTPMIMENIQELIR

ACRBP

276

Q8NEB7
TLNRDINMMDILTTP

MASTL

181

Q96GX5
PLAAQEMSVRMSNLE

CACHD1

1131

Q5VU97
VQRTMLMDEQPLLDR

DGKQ

456

P52824
ALEEEMLQMQESTRL

DNAH11

1291

Q96DT5
LEEFMNPSLTEDELM

DNAH11

4161

Q96DT5
DMMTNQRDEELPTLL

PIK3AP1

326

Q6ZUJ8
PTEMELIELSQQINM

CABP1

261

Q9NZU7
VRLPDDMSALQMAII

CDH23

3056

Q9H251
LMRESKPEDIQMITE

FAM184A

981

Q8NB25
SPRMDLTLAELQEMA

TP53BP2

121

Q13625
LPEADQQMLRDLMSD

ATG2B

1401

Q96BY7
PDLARDLANDIMTLM

AP3D1

141

O14617
VMLRMLPQAATEDDI

RBM10

131

P98175
SNLPLSMDEQELENM

RBMS1

146

P29558
NLPISMDEQELENML

RBMS3

146

Q6XE24
LLEMLLEQRSSMPVE

PCDH12

1116

Q9NPG4
DALENIDPATQMMIL

SERPIND1

276

P05546
DLLSQAVMMVENSRP

KIAA0895L

246

Q68EN5
TLMRPQEETVAALMD

ARHGAP10

541

A1A4S6
LIADPDEMRMQALLI

FEM1C

311

Q96JP0
TEMLMSELSPEDQRV

FAR2

406

Q96K12
DIESLQREIQMDSPM

MAPK7

791

Q13164
QREIQMDSPMLLADL

MAPK7

796

Q13164
TDPQLMRLDNMLLAE

PBX1

101

P40424
LMDLETPEEMQARSL

C19orf81

26

C9J6K1
NLMLELETSQSPCMQ

COLQ

81

Q9Y215
VDPQLMRLDNMLLAE

PBX2

111

P40425
LQQPLMVSLSEEMEN

KLF3

161

P57682
SDLARDMLMQERITP

LEXM

386

Q3ZCV2
NNMDQTVMVPSLLRD

MID1IP1

26

Q9NPA3
MPEVVQLRMTENILE

FAM13B

261

Q9NYF5
SPQSDMMREQLQLSE

MCM3AP

1926

O60318
MGNREMEELIPLVNR

DNM3

1

Q9UQ16
DEIMQQEVRPLMAVE

MCF2L2

26

Q86YR7
QLTRMGPTELLIEME

FGB

331

P02675
EDDMLDMAPLLQENS

FDX2

136

Q6P4F2
PEDDTSMAILSMLQD

PDE2A

611

O00408
PLVMDNLDSIMEQLN

PDE3A

676

Q14432
DEELLAMEIRMRGQP

PEAK1

256

Q9H792
MIPSLDDIQQAINRM

DNAH8

896

Q96JB1
ELMPDVGRSMQQLLD

HERC4

836

Q5GLZ8
IIRPQKQEMTDDMDS

GLYATL1

56

Q969I3
TLMRDERGLPAMNNL

ONECUT2

196

O95948
ETLRSEMEMFNVPEL

MEFV

576

O15553
LRMAVMLPEGEDLNE

MOB1B

41

Q7L9L4
MRDQMLLEDVLPVQE

ENPEP

436

Q07075
PTLQEMIQMAAEIAD

INSR

1131

P06213
EMLRDPELRSKMISN

CDC42BPB

1571

Q9Y5S2
QLLTMLSPLEMELRT

HECTD4

3851

Q9Y4D8
LQPQTGEITNRMMDL

MFSD6

226

Q6ZSS7
LEPVLMQRVMIDAAS

HELZ

371

P42694
DQMRSAEQTRLMPAE

PASD1

751

Q8IV76
MVRILIMDINDNAPE

PCDHB4

226

Q9Y5E5
LLFIMLDQMDPEQDR

MCM3

481

P25205
LDPSLMEMTEAALRL

ALPP

306

P05187
MEMTEAALRLLSRNP

ALPP

311

P05187
LSPDLQSMEQIRRIM

PPP1CA

176

P62136
PLMVSDRMDLDTLAR

ITPRIPL1

26

Q6GPH6
LMASEMIALNRSLPD

GALNT1

86

Q10472
MIINEELMASLDQPT

EIF3CL

826

B5ME19
MDAPRRDMELLSNSL

EVA1B

1

Q9NVM1
SSMAQLPMEELNRIQ

HTT

2026

P42858
MESEEFMLLPANQLI

KLHL20

201

Q9Y2M5
MEDEVENIISSMRPQ

DNAH17

2886

Q9UFH2
MEQKARLQTSLTEPM

DOK6

241

Q6PKX4
VPEMEESGAQLLLEM

CDK4

261

P11802
MAVRMIQNSPDNIEL

FRMPD2

841

Q68DX3
LLQDPDIDAASAMML

FOXN3

246

O00409
EALITDPDEMRMQAL

FEM1A

361

Q9BSK4
IIRPQKQEMTDDMDS

GLYATL1B

56

A0A0U1RQE8
LTGRREPLQMEDSNM

BAHD1

16

Q8TBE0
LLNQTSRMDAQMPET

ANGPT4

156

Q9Y264
DLMRMTAILQTDVPE

ANK3

1911

Q12955
SRMEPMNLLVDDPNE

DUXB

161

A0A1W2PPF3
LMMELSEDCPSIQDR

CRYGC

101

P07315
VMQLPDSGLEIRDRM

DVL1

421

O14640
AEALMMPLVDQLENR

HEATR1

2016

Q9H583
LLTMMPTEEERQKIE

FHOD1

736

Q9Y613
LMRSPELDAMAALND

CHN1

426

P15882
VMQLPDSGLEIRDRM

DVL1P1

396

P54792
IMESPANSIEMLLSN

SCNN1G

516

P51170
LPLEMSSIAALENQM

SALL1

856

Q9NSC2
RNMDIRENLLDPGMA

SACS

1501

Q9NZJ4
PREEMLQMQDIVLNE

POLB

151

P06746
MNLALLSSPEDMIEA

IFT140

1056

Q96RY7
EELMLQDETLLGTMQ

PPRC1

81

Q5VV67
ISQLDPVNERMLNMI

DHX9

1121

Q08211
EVMDSPMEEVLLVNL

DENND2D

316

Q9H6A0
MPSRELASMNLDIVD

RHOBTB3

521

O94955
DLLRENSMLQEEIAM

POTEC

521

B2RU33
ALLPSELEMQQMEET

TAF8

226

Q7Z7C8
NISSIMPSNEMDLQL

SENP7

506

Q9BQF6
IEIAEQEMPALMALR

AHCYL2

201

Q96HN2
QQIMSDPAMRLILEQ

STIP1

496

P31948
RLNSMLMEVEEPEVL

NBPF14

841

Q5TI25
ELMVLNVPRLMTQDC

F7

356

P08709
DENTTVRVPMMLQDQ

SERPINA4

236

P29622
LDQEPDVRNRMSSSM

MEP1A

511

Q16819
EVPMTLAELSALMQR

SLC39A4

216

Q6P5W5
NMENERIPFDLMDTV

ARHGAP35

396

Q9NRY4
QDRLMDLPVLSMDLS

STON2

546

Q8WXE9
LMALDPMELRIVQNC

CNNM4

206

Q6P4Q7
DTMLLNIPLVMNNER

RNF213

3671

Q63HN8
CPLAQLMDSETDMVR

VPS51

81

Q9UID3
NQRRMNADPLEVMLL

WDTC1

631

Q8N5D0
RMAEDTSPNMNDNIL

SUN5

36

Q8TC36
EENPRNQLMALMLLT

ZNF197

196

O14709
ALVRLEMIAMENPAD

UBE3A

536

Q05086
APLEIGMRMNSRQLE

MLN

81

P12872
MSSNVPADMINLRLI

UBL3

1

O95164
DLVRMSSMQLAPQEL

SPOCD1

691

Q6ZMY3
RQTLELARNPAMMQE

UBQLN1

236

Q9UMX0
PESQEMLEEQLVRML

XPO5

951

Q9HAV4
LQALEREPMNLASQM

SCAI

301

Q8N9R8
MQLRRPSDQEVSESM

REL

261

Q04864
MGETDNPRLLSMNLE

REL

506

Q04864
LSPDLQSMEQIRRIM

PPP1CC

176

P36873
PSMQDLLEEASSRDM

ZNF333

86

Q96JL9
MEMEDEERNALLQLT

SNRNP200

1986

O75643
EMEQLRISPATMLED

USP24

1526

Q9UPU5
MLDREASSLPQLVEM

SLC4A4

171

Q9Y6R1
QFLVMDLPMVSEDRL

SCN11A

1666

Q9UI33
PIQLMDRLSNESIML

STRCP1

1266

A6NGW2
MMNLLLDIVQDQTSP

TBCD

81

Q9BTW9
LESRLDLIAQQMMPE

ATP6V1E1

196

P36543
LNRLSLASEMPLMDN

PLEKHG1

931

Q9ULL1
REIESRLQLMSMDCP

TRANK1

2546

O15050
RLQIDPVMAETLQMS

ZC3H14

436

Q6PJT7
EELDMDVMRPLINEQ

SLC36A4

16

Q6YBV0
MPLQELSNALMAAER

TSC2

1226

P49815
MESVRIEQMLSLPAE

LONRF3

1

Q496Y0
QLQGPQEMERIRMDS

MXI1

146

P50539
LFMDLIELMQSSELP

MYO1E

526

Q12965
SVPQDLMMEELSLRN

MYOZ3

31

Q8TDC0
LLPDAMNIELTRNMN

NEB

2146

P20929