Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiondeoxyguanosine kinase activity

DCK DGUOK

2.90e-0521082GO:0004138
GeneOntologyMolecularFunctiondeoxyadenosine kinase activity

DCK DGUOK

8.66e-0531082GO:0004136
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DYNC2H1 DNAH8 DNAH9

1.18e-04181083GO:0008569
GeneOntologyMolecularFunctiondeoxynucleoside kinase activity

DCK DGUOK

2.87e-0451082GO:0019136
GeneOntologyMolecularFunctiondynein light intermediate chain binding

DYNC2H1 DNAH8 DNAH9

4.57e-04281083GO:0051959
GeneOntologyBiologicalProcessdAMP biosynthetic process

DCK DGUOK

8.27e-0531092GO:0006170
GeneOntologyBiologicalProcessdAMP salvage

DCK DGUOK

8.27e-0531092GO:0106383
GeneOntologyBiologicalProcesspurine deoxyribonucleotide salvage

DCK DGUOK

8.27e-0531092GO:0106381
GeneOntologyBiologicalProcesspurine deoxyribonucleoside monophosphate biosynthetic process

DCK DGUOK

8.27e-0531092GO:0009171
GeneOntologyBiologicalProcesspurine nucleotide salvage

DCK DGUOK GMPR

1.31e-04191093GO:0032261
DomainDHC_N1

DYNC2H1 DNAH8 DNAH9

1.06e-0581093PF08385
DomainDynein_heavy_dom-1

DYNC2H1 DNAH8 DNAH9

1.06e-0581093IPR013594
DomainELM2

RCOR2 RCOR1 RCOR3

5.30e-05131093PF01448
DomainELM2

RCOR2 RCOR1 RCOR3

5.30e-05131093PS51156
DomainELM2_dom

RCOR2 RCOR1 RCOR3

5.30e-05131093IPR000949
DomainELM2

RCOR2 RCOR1 RCOR3

5.30e-05131093SM01189
DomainDynein_heavy_chain_D4_dom

DYNC2H1 DNAH8 DNAH9

6.72e-05141093IPR024317
DomainDynein_HC_stalk

DYNC2H1 DNAH8 DNAH9

6.72e-05141093IPR024743
DomainDynein_heavy_dom-2

DYNC2H1 DNAH8 DNAH9

6.72e-05141093IPR013602
DomainDHC_N2

DYNC2H1 DNAH8 DNAH9

6.72e-05141093PF08393
DomainMT

DYNC2H1 DNAH8 DNAH9

6.72e-05141093PF12777
DomainAAA_8

DYNC2H1 DNAH8 DNAH9

6.72e-05141093PF12780
DomainATPase_dyneun-rel_AAA

DYNC2H1 DNAH8 DNAH9

6.72e-05141093IPR011704
DomainAAA_5

DYNC2H1 DNAH8 DNAH9

6.72e-05141093PF07728
DomainDHC_fam

DYNC2H1 DNAH8 DNAH9

8.36e-05151093IPR026983
DomainDynein_heavy_dom

DYNC2H1 DNAH8 DNAH9

8.36e-05151093IPR004273
DomainDynein_heavy

DYNC2H1 DNAH8 DNAH9

8.36e-05151093PF03028
DomaindNK

DCK DGUOK

2.01e-0441092PF01712
DomainPP2A_PR55

PPP2R2A PPP2R2C

2.01e-0441092IPR000009
DomainDCK/DGK

DCK DGUOK

2.01e-0441092IPR002624
DomainPP2A_PR55_CS

PPP2R2A PPP2R2C

2.01e-0441092IPR018067
DomainDUF4195

ZNF280D ZNF280B

2.01e-0441092PF13836
DomainDNK_dom

DCK DGUOK

2.01e-0441092IPR031314
DomainDUF4195

ZNF280D ZNF280B

2.01e-0441092IPR025243
DomainPR55_2

PPP2R2A PPP2R2C

2.01e-0441092PS01025
DomainPR55_1

PPP2R2A PPP2R2C

2.01e-0441092PS01024
DomainDCN-prot

DCUN1D1 DCUN1D2

3.34e-0451092IPR014764
DomainPONY_dom

DCUN1D1 DCUN1D2

3.34e-0451092IPR005176
DomainDCUN1

DCUN1D1 DCUN1D2

3.34e-0451092PS51229
DomainCullin_binding

DCUN1D1 DCUN1D2

3.34e-0451092PF03556
DomainSANT_dom

RCOR2 RCOR1 RCOR3

4.56e-04261093IPR017884
DomainHaem_d1

EML6 WDR19

4.99e-0461092IPR011048
DomainSANT

RCOR2 RCOR1 RCOR3

5.70e-04281093PS51293
Domain-

PLA2G7 YTHDC2 ACOT1 TG LIPG

6.65e-0411910953.40.50.1820
DomainAB_hydrolase

PLA2G7 YTHDC2 ACOT1 TG LIPG

6.65e-041191095IPR029058
DomainWD40

EML6 WDFY4 WDR19 PPP2R2A PPP2R2C WDR87 DCAF12

8.15e-042591097PF00400
DomainWD40

EML6 WDFY4 WDR19 PPP2R2A PPP2R2C WDR87 DCAF12

9.94e-042681097SM00320
DomainARM-like

ATR STAG1 WDFY4 RIC8B PSME4 MROH2B LTN1

1.04e-032701097IPR011989
DomainWD40_repeat

EML6 WDFY4 WDR19 PPP2R2A PPP2R2C WDR87 DCAF12

1.08e-032721097IPR001680
DomainMyb_DNA-binding

RCOR2 RCOR1 RCOR3

1.10e-03351093PF00249
DomainKRAB

ZNF729 ZNF189 ZNF736 ZNF112 ZNF732 ZNF718 ZNF43 ZNF727

1.19e-033581098PS50805
DomainKRAB

ZNF729 ZNF189 ZNF736 ZNF112 ZNF732 ZNF718 ZNF43 ZNF727

1.19e-033581098PF01352
DomainWD_REPEATS_1

EML6 WDFY4 WDR19 PPP2R2A PPP2R2C WDR87 DCAF12

1.23e-032781097PS00678
DomainWD_REPEATS_2

EML6 WDFY4 WDR19 PPP2R2A PPP2R2C WDR87 DCAF12

1.25e-032791097PS50082
DomainWD_REPEATS_REGION

EML6 WDFY4 WDR19 PPP2R2A PPP2R2C WDR87 DCAF12

1.25e-032791097PS50294
DomainMYB_LIKE

RCOR2 RCOR1 RCOR3

1.41e-03381093PS50090
DomainKRAB

ZNF729 ZNF189 ZNF736 ZNF112 ZNF732 ZNF718 ZNF43 ZNF727

1.44e-033691098SM00349
DomainKRAB

ZNF729 ZNF189 ZNF736 ZNF112 ZNF732 ZNF718 ZNF43 ZNF727

1.47e-033701098IPR001909
DomainWD40_repeat_dom

EML6 WDFY4 WDR19 PPP2R2A PPP2R2C WDR87 DCAF12

1.79e-032971097IPR017986
DomainSANT

RCOR2 RCOR1 RCOR3

3.10e-03501093SM00717
Domain-

EML6 WDFY4 WDR19 PPP2R2A PPP2R2C WDR87 DCAF12

3.39e-0333310972.130.10.10
Domainzf-RING_2

MYCBP2 RNF103 LTN1

3.47e-03521093PF13639
DomainSANT/Myb

RCOR2 RCOR1 RCOR3

3.47e-03521093IPR001005
DomainWD40/YVTN_repeat-like_dom

EML6 WDFY4 WDR19 PPP2R2A PPP2R2C WDR87 DCAF12

3.51e-033351097IPR015943
DomainARM-type_fold

ATR STAG1 WDFY4 RIC8B PSME4 MROH2B LTN1

3.74e-033391097IPR016024
DomainGlobin-like

ATR HECTD2

3.84e-03161092IPR009050
DomainZINC_FINGER_C2H2_2

ZNF729 ZNF137P ZNF280D ZNF189 ZNF280B ZNF736 ZNF112 ZNF732 ZNF718 ZNF43 ZNF727

5.58e-0377510911PS50157
DomainZINC_FINGER_C2H2_1

ZNF729 ZNF137P ZNF280D ZNF189 ZNF280B ZNF736 ZNF112 ZNF732 ZNF718 ZNF43 ZNF727

5.69e-0377710911PS00028
PathwayREACTOME_PURINE_SALVAGE

DCK DGUOK GMPR

5.01e-0513813M814
PathwayREACTOME_PURINE_SALVAGE

DCK DGUOK GMPR

5.01e-0513813MM15438
Pubmed

Regulator of sex-limitation (Rsl) encodes a pair of KRAB zinc-finger genes that control sexually dimorphic liver gene expression.

ZNF729 ZNF736 ZNF718 ZNF43 ZNF727

3.70e-0829113514563677
Pubmed

Antagonistic actions of Rcor proteins regulate LSD1 activity and cellular differentiation.

RCOR2 RCOR1 RCOR3

6.63e-076113324843136
Pubmed

Corepressor Rcor1 is essential for murine erythropoiesis.

RCOR2 RCOR1 RCOR3

6.63e-076113324652990
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

ATR YTHDC2 SMG8 LIG4 SULF2 PSME4 TCERG1 RAD54B PIP5K1A EIF2AK4 CMTR2 ANAPC5

1.46e-066501131238777146
Pubmed

Epigenetic regulation of hematopoietic differentiation by Gfi-1 and Gfi-1b is mediated by the cofactors CoREST and LSD1.

RCOR2 RCOR1 RCOR3

1.85e-068113317707228
Pubmed

Mediator kinase inhibition further activates super-enhancer-associated genes in AML.

CDK8 CDK19

1.05e-052113226416749
Pubmed

CDK8/19 Mediator kinases potentiate induction of transcription by NFκB.

CDK8 CDK19

1.05e-052113228855340
Pubmed

Inhibition of Cyclin-Dependent Kinase 8/Cyclin-Dependent Kinase 19 Suppresses Its Pro-Oncogenic Effects in Prostate Cancer.

CDK8 CDK19

1.05e-052113235181333
Pubmed

Regulatory functions of the Mediator kinases CDK8 and CDK19.

CDK8 CDK19

1.05e-052113230585107
Pubmed

Structure and function of cellular deoxyribonucleoside kinases.

DCK DGUOK

1.05e-052113212363036
Pubmed

Pan-Cancer Analysis of the Mediator Complex Transcriptome Identifies CDK19 and CDK8 as Therapeutic Targets in Advanced Prostate Cancer.

CDK8 CDK19

1.05e-052113227678455
Pubmed

HIV Transcription Is Independent of Mediator Kinases.

CDK8 CDK19

1.05e-052113231044597
Pubmed

CDK8 and CDK19 regulate intestinal differentiation and homeostasis via the chromatin remodeling complex SWI/SNF.

CDK8 CDK19

1.05e-052113236006697
Pubmed

TL1A is an epithelial alarmin that cooperates with IL-33 for initiation of allergic airway inflammation.

TNFSF15 IL33

1.05e-052113238597952
Pubmed

CDK8 and CDK19: positive regulators of signal-induced transcription and negative regulators of Mediator complex proteins.

CDK8 CDK19

1.05e-052113237378433
Pubmed

The histone demethylase KDM3A, and its downstream target MCAM, promote Ewing Sarcoma cell migration and metastasis.

KDM3A MCAM

1.05e-052113228319067
Pubmed

Inorganic tripolyphosphate (PPP(i)) as a phosphate donor for human deoxyribonucleoside kinases.

DCK DGUOK

1.05e-052113212535661
Pubmed

Cyclin-Dependent Kinases 8 and 19 Regulate Host Cell Metabolism during Dengue Virus Serotype 2 Infection.

CDK8 CDK19

1.05e-052113232560467
Pubmed

HIV-1 infection of microglial cells in a reconstituted humanized mouse model and identification of compounds that selectively reverse HIV latency.

RCOR2 RCOR1

1.05e-052113229256041
Pubmed

Epithelial-Mesenchymal Transition in Asthma Airway Remodeling Is Regulated by the IL-33/CD146 Axis.

MCAM IL33

1.05e-052113232793232
Pubmed

RNAi depletion of deoxycytidine and deoxyguanosine kinase in human leukemic CEM cells.

DCK DGUOK

1.05e-052113218600530
Pubmed

[Mechanisms of transcriptional regulation upon protein phosphorylation by mediator complexes].

CDK8 CDK19

1.05e-052113220408451
Pubmed

Identification of target genes for the CDK subunits of the Mediator complex.

CDK8 CDK19

1.05e-052113222117896
Pubmed

Rapid and efficient cloning of cDNAs encoding Krüppel-like zinc finger proteins by degenerate PCR.

ZNF729 ZNF736 ZNF43 ZNF727

2.00e-054911349630514
Pubmed

Molecular mechanisms involved in HIV-1-Tat mediated inhibition of telomerase activity in human CD4(+) T lymphocytes.

PPP2R2A PPP2R2C HSP90AB1

2.63e-0518113323287597
Pubmed

Mediator complex cooperatively regulates transcription of retinoic acid target genes with Polycomb Repressive Complex 2 during neuronal differentiation.

CDK8 CDK19

3.13e-053113226002960
Pubmed

Activation of HIV transcription by the viral Tat protein requires a demethylation step mediated by lysine-specific demethylase 1 (LSD1/KDM1).

RCOR2 RCOR1

3.13e-053113221876670
Pubmed

Cell cycle dependent regulation of deoxycytidine kinase, deoxyguanosine kinase, and cytosolic 5'-nucleotidase I activity in MOLT-4 cells.

DCK DGUOK

3.13e-053113217065091
Pubmed

Phosphoprotein Phosphatase 1 Is Required for Extracellular Calcium-Induced Keratinocyte Differentiation.

PIP5K1A PLCG1

3.13e-053113227340655
Pubmed

Brain protein phosphatase 2A: developmental regulation and distinct cellular and subcellular localization by B subunits.

PPP2R2A PPP2R2C

3.13e-05311329514514
Pubmed

MCAM/CD146 Signaling via PLCγ1 Leads to Activation of β1-Integrins in Memory T-Cells Resulting in Increased Brain Infiltration.

MCAM PLCG1

3.13e-053113233381120
Pubmed

Mediator cyclin-dependent kinases upregulate transcription of inflammatory genes in cooperation with NF-κB and C/EBPβ on stimulation of Toll-like receptor 9.

CDK8 CDK19

3.13e-053113228151579
Pubmed

The functional interactome landscape of the human histone deacetylase family.

STAG1 MYCBP2 RCOR2 PPP2R2A RCOR1 SVIL RCOR3

4.64e-05289113723752268
Pubmed

Mutations of the Transcriptional Corepressor ZMYM2 Cause Syndromic Urinary Tract Malformations.

ZNF280D ZNF280B RCOR2 RCOR1 RCOR3

5.70e-05125113532891193
Pubmed

The co-repressor mSin3A is a functional component of the REST-CoREST repressor complex.

RCOR2 RCOR1

6.25e-054113210734093
Pubmed

Loss of Cyclin C or CDK8 provides ATR inhibitor resistance by suppressing transcription-associated replication stress.

CDK8 ATR

6.25e-054113234329458
Pubmed

Oncogenic exon 2 mutations in Mediator subunit MED12 disrupt allosteric activation of cyclin C-CDK8/19.

CDK8 CDK19

6.25e-054113229440396
Pubmed

p120-catenin regulates REST and CoREST, and modulates mouse embryonic stem cell differentiation.

RCOR2 RCOR1

6.25e-054113225074806
Pubmed

SFMBT1 functions with LSD1 to regulate expression of canonical histone genes and chromatin-related factors.

RCOR2 RCOR1

6.25e-054113223592795
Pubmed

Phospholipase cgamma1 is required for activation of store-operated channels in human keratinocytes.

TRPC1 PLCG1

6.25e-054113215654973
Pubmed

Evolution of KRAB-containing zinc finger proteins and their roles in species evolution.

ZNF732 ZNF727

6.25e-054113227867147
Pubmed

Zinc fingers function cooperatively with KRAB domain for nuclear localization of KRAB-containing zinc finger proteins.

ZNF732 ZNF727

6.25e-054113224647005
Pubmed

Cdk8 is required for establishment of H3K27me3 and gene repression by Xist and mouse development.

CDK8 CDK19

6.25e-054113232439758
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

CDK8 MYCBP2 SPTB CDK19 ZNF189 ARHGAP39 PPP2R2A PPP2R2C RIC8B ZNF718 RALGPS1 PIP5K1A RCOR3 EIF2AK4 PLCG1

9.76e-0514891131528611215
Pubmed

Mammalian telomeres resemble fragile sites and require TRF1 for efficient replication.

ATR LIG4

1.04e-045113219596237
Pubmed

Activation of protein phosphatase-2A1 by HIV-1 Vpr cell death causing peptide in intact CD(4+) T cells and in vitro.

PPP2R2A PPP2R2C

1.04e-045113215578586
Pubmed

CDK8 and CDK19 act redundantly to control the CFTR pathway in the intestinal epithelium.

CDK8 CDK19

1.04e-045113236545778
Pubmed

CoREST/LSD1 control the development of pyramidal cortical neurons.

RCOR2 RCOR1

1.04e-045113221878487
Pubmed

Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.

STAG1 LIPG GMPR

1.27e-0430113319936222
Pubmed

Cys2His2 zinc finger protein family: classification, functions, and major members.

ZNF732 ZNF727

1.56e-046113222803940
Pubmed

Corepressor-dependent silencing of fetal hemoglobin expression by BCL11A.

RCOR2 RCOR1

1.56e-046113223576758
Pubmed

Werner syndrome protein participates in a complex with RAD51, RAD54, RAD54B and ATR in response to ICL-induced replication arrest.

ATR RAD54B

1.56e-046113217118963
Pubmed

The chromatin modifying complex CoREST/LSD1 negatively regulates notch pathway during cerebral cortex development.

RCOR2 RCOR1

1.56e-046113227112428
Pubmed

Isolation of a cDNA encoding thymic shared antigen-1. A new member of the Ly6 family with a possible role in T cell development.

SPTB TG

1.56e-04611328258699
Pubmed

UCHL1 regulates ubiquitination and recycling of the neural cell adhesion molecule NCAM.

SPTB PLCG1

1.56e-046113223061666
Pubmed

Gfi1b regulates the level of Wnt/β-catenin signaling in hematopoietic stem cells and megakaryocytes.

RCOR2 RCOR1 RCOR3

1.86e-0434113330894540
Pubmed

HSF1 transcriptional activity is modulated by IER5 and PP2A/B55.

PPP2R2A PPP2R2C

2.17e-047113225816751
Pubmed

Mammalian homologues of the Drosophila Son of sevenless gene map to murine chromosomes 17 and 12 and to human chromosomes 2 and 14, respectively.

SPTB LAMA1

2.17e-04711328276400
Pubmed

The conserved protein DCN-1/Dcn1p is required for cullin neddylation in C. elegans and S. cerevisiae.

DCUN1D1 DCUN1D2

2.17e-047113215988528
Pubmed

Mediator CDK subunits are platforms for interactions with various chromatin regulatory complexes.

CDK8 CDK19

2.17e-047113222668559
Pubmed

Mutations in DNAH17, Encoding a Sperm-Specific Axonemal Outer Dynein Arm Heavy Chain, Cause Isolated Male Infertility Due to Asthenozoospermia.

DNAH8 DNAH9

2.17e-047113231178125
Pubmed

Regulator of G protein signaling 12 drives inflammatory arthritis by activating synovial fibroblasts through MYCBP2/KIF2A signaling.

MYCBP2 LTN1

2.17e-047113236700049
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

ZNF280D ATR DYNC2H1 TRPC1 YTHDC2 PPA1 URB2 STT3B PPP2R2A RIC8B TCERG1 PLCG1 TALDO1 HSP90AB1

2.19e-0414251131430948266
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

KDM3A STAG1 MYCBP2 SPTB ZNF189 ACOT1 WDR19 USP8 MIA2 TCERG1 HECTD2 PLCG1 HSP90AB1

2.82e-0412851131335914814
Pubmed

The Cdk8/19-cyclin C transcription regulator functions in genome replication through metazoan Sld7.

CDK8 CDK19

2.89e-048113230695077
Pubmed

The role of Vpr in HIV-1 pathogenesis.

PPP2R2A PPP2R2C

2.89e-048113215638722
Pubmed

Type 2A protein phosphatase, the complex regulator of numerous signaling pathways.

PPP2R2A PPP2R2C

2.89e-048113211007961
Pubmed

Mediator complex recruits epigenetic regulators via its two cyclin-dependent kinase subunits to repress transcription of immune response genes.

CDK8 CDK19

2.89e-048113223749998
Pubmed

Cell cycle-related kinase is a crucial regulator for ciliogenesis and Hedgehog signaling in embryonic mouse lung development.

DYNC2H1 WDR19 DNAH9

3.02e-0440113332317081
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

KDM3A ATG2A WDR19 PPP2R2A SULF2 PSME4 RALGPS1 EIF2AK4

3.44e-04529113814621295
Pubmed

Prediction of the coding sequences of unidentified human genes. II. The coding sequences of 40 new genes (KIAA0041-KIAA0080) deduced by analysis of cDNA clones from human cell line KG-1.

USP8 RCOR1 PSME4

3.50e-044211337584044
Pubmed

Akt-dependent Pp2a activity is required for epidermal barrier formation during late embryonic development.

PPP2R2A PPP2R2C

3.71e-049113219762425
Pubmed

Direct binding of CoREST1 to SUMO-2/3 contributes to gene-specific repression by the LSD1/CoREST1/HDAC complex.

RCOR2 RCOR1 RCOR3 HSP90AB1

4.07e-04106113419394292
Pubmed

Chemoproteomics profiling of HDAC inhibitors reveals selective targeting of HDAC complexes.

RCOR2 RCOR1 RCOR3

4.29e-0445113321258344
Pubmed

A PP2A phosphatase high density interaction network identifies a novel striatin-interacting phosphatase and kinase complex linked to the cerebral cavernous malformation 3 (CCM3) protein.

STRIP1 PPP2R2A PPP2R2C

4.58e-0446113318782753
Pubmed

Opposing LSD1 complexes function in developmental gene activation and repression programmes.

KDM3A RCOR2 RCOR1

4.58e-0446113317392792
Pubmed

Foxa2 acts as a co-activator potentiating expression of the Nurr1-induced DA phenotype via epigenetic regulation.

RCOR2 RCOR1

4.63e-0410113224496614
Pubmed

Functional analysis of the SRY-KRAB interaction in mouse sex determination.

ZNF729 ZNF43

4.63e-0410113218588511
Pubmed

Multiple mouse chromosomal loci for dynein-based motility.

DYNC2H1 DNAH8 DNAH9

4.88e-044711338812413
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

ATR MYCBP2 GRAMD1A LAMA1 MCAM STT3B PPP2R2A SULF2 MIA2 SVIL LTN1 DCAF12

5.45e-0412011131235696571
Pubmed

Sry associates with the heterochromatin protein 1 complex by interacting with a KRAB domain protein.

ZNF729 ZNF43

5.65e-0411113215469996
Pubmed

Bipolar I disorder and schizophrenia: a 440-single-nucleotide polymorphism screen of 64 candidate genes among Ashkenazi Jewish case-parent trios.

GRID1 GRM4

5.65e-0411113216380905
Pubmed

REST and its corepressors mediate plasticity of neuronal gene chromatin throughout neurogenesis.

RCOR2 RCOR1

5.65e-0411113215907476
Pubmed

The IFT-A complex regulates Shh signaling through cilia structure and membrane protein trafficking.

DYNC2H1 WDR19

5.65e-0411113222689656
Pubmed

Full-length transcriptome analysis of human retina-derived cell lines ARPE-19 and Y79 using the vector-capping method.

RCOR2 PSME4 CEP250 LTN1

6.49e-04120113421697133
Pubmed

A genome-wide search for loci interacting with known prostate cancer risk-associated genetic variants.

CHL1 ZNF280B ACOXL

6.57e-0452113322219177
Pubmed

The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.

MYCBP2 STRIP1 PSME4 LTN1 PIPSL

6.61e-04212113533853758
Pubmed

A conserved Mediator-CDK8 kinase module association regulates Mediator-RNA polymerase II interaction.

CDK8 CDK19

6.76e-0412113223563140
Pubmed

The human Dcn1-like protein DCNL3 promotes Cul3 neddylation at membranes.

DCUN1D1 DCUN1D2

6.76e-0412113219617556
Pubmed

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.

ATR ZNF189 DCK STT3B PPP2R2A MAP3K9 EIF2AK4 DDX60L PLCG1 ANAPC5

7.85e-049101131036736316
Pubmed

Epigenetic gene silencing by the SRY protein is mediated by a KRAB-O protein that recruits the KAP1 co-repressor machinery.

ZNF729 ZNF43

7.97e-0413113219850934
Pubmed

Structural conservation of distinctive N-terminal acetylation-dependent interactions across a family of mammalian NEDD8 ligation enzymes.

DCUN1D1 DCUN1D2

7.97e-0413113223201271
Pubmed

Bromodomain protein Brd4 regulates human immunodeficiency virus transcription through phosphorylation of CDK9 at threonine 29.

PPP2R2A PPP2R2C

7.97e-0413113218971272
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

WDFY4 RPS6KC1 RCOR1 DCUN1D1 PSME4 UNC5C LTN1 MAP3K9 RCOR3 EIF2AK4 PLCG1

8.24e-0410841131111544199
Pubmed

Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.

DYNC2H1 DNAH8

9.28e-041411329373155
Pubmed

Direct activation of protein phosphatase-2A0 by HIV-1 encoded protein complex NCp7:vpr.

PPP2R2A PPP2R2C

9.28e-041411329013886
Pubmed

Pot1a prevents telomere dysfunction and ATM-dependent neuronal loss.

ATR LIG4

9.28e-0414113224899707
Pubmed

Increasing the ratio of PP2A core enzyme to holoenzyme inhibits Tat-stimulated HIV-1 transcription and virus production.

PPP2R2A PPP2R2C

9.28e-041411329400615
Pubmed

Dephosphorylation of CDK9 by protein phosphatase 2A and protein phosphatase-1 in Tat-activated HIV-1 transcription.

PPP2R2A PPP2R2C

9.28e-0414113216048649
Pubmed

Genome-wide SNP associations with rubella-specific cytokine responses in measles-mumps-rubella vaccine recipients.

CDK8 DNAH9

9.28e-0414113224811271
GeneFamilyWD repeat domain containing

EML6 WDFY4 WDR19 PPP2R2A PPP2R2C WDR87 DCAF12

9.74e-05262747362
GeneFamilyGATA zinc finger domain containing|Myb/SANT domain containing

RCOR2 RCOR1 RCOR3

1.33e-0353743532
GeneFamilyWD repeat domain containing|Protein phosphatase 2 regulatory subunits

PPP2R2A PPP2R2C

1.68e-0315742696
GeneFamilyDyneins, axonemal

DNAH8 DNAH9

2.16e-0317742536
CoexpressionGSE17721_4_VS_24H_CPG_BMDC_DN

CDK8 KDM3A STAG1 GRAMD1A RNF103 DGUOK SMPD2 CMTR2 ANAPC5 PAQR7

1.68e-0820011310M4131
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

CDK8 KDM3A ATR STAG1 MYCBP2 TRPC1 CDK19 RYK PPP2R2A RCOR1 FAM193A MIA2 PSME4 LTN1 PIP5K1A ATP13A3 KAZN

1.57e-0785611317M4500
CoexpressionGSE7568_CTRL_VS_3H_TGFB_TREATED_MACROPHAGES_WITH_IL4_AND_DEXAMETHASONE_DN

YTHDC2 STRIP1 PPP2R2A PSME4 RNF103 SVIL ATP13A3 PLCG1

6.66e-071671138M361
ToppCellfacs-Heart-Unknown-3m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA1 GRID1 COL24A1 TEX26 DNAH9 TNFSF15

1.63e-0614111364aa4b3476dc5abefbd348353cfe711cd5fe3d52f
ToppCellfacs-Heart-Unknown-3m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA1 GRID1 COL24A1 TEX26 DNAH9 TNFSF15

1.63e-061411136e40c6f1b7fbaa46b3eaa55f1b37ef360b04370a8
ToppCelldroplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATR GRAMD1A EML6 BFAR URB2 PLCG1

3.05e-061571136a426c54fd1545093d41426e9620862f71bd06f6b
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-SPN_Neuron_STR|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CAPN9 ANKRD35 SYT6 GRM4 RCOR2 HECTD2

4.06e-0616511361b7dfa173e83aa8c46a3153a3261866c065c3b73
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-medium_spiny_neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CAPN9 ANKRD35 SYT6 GRM4 RCOR2 HECTD2

4.06e-061651136b4f7d33af7d053ec07b01bd67d861600a9c4822e
ToppCellLPS-antiTNF-Hematopoietic_Meg-Ery-Erythroid|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SPTB DCK DCUN1D1 GMPR TALDO1 DCAF12

6.27e-061781136eafacc8cd3e986d6ca309e05b6e241331a584fa5
ToppCellLPS-antiTNF-Hematopoietic_Meg-Ery|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SPTB DCK DCUN1D1 GMPR TALDO1 DCAF12

6.27e-0617811366a5c31e976852edc7d9e899da8e2a1bf23d36759
ToppCellLPS-antiTNF-Hematopoietic_Meg-Ery-Erythroid-Erythroid|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SPTB DCK DCUN1D1 GMPR TALDO1 DCAF12

6.27e-061781136370749834a11d981e9ede26d5f63f0ecb551c015
ToppCelldroplet-Limb_Muscle-nan-21m-Macroglial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHL1 PLA2G7 FAM184A MCAM ARHGAP39 EFHB

7.12e-061821136a512863304fad80acaab60a8c6107eb7c9cbac99
ToppCellrenal_medulla_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

PDE1A STAG1 EML6 LAMA1 MACROD2 KAZN

8.83e-061891136830d9cd0dd706bce22eb2416f07b2c31c870a05a
ToppCellTCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Tubular|TCGA-Stomach / Sample_Type by Project: Shred V9

ATR URB2 ARHGAP39 MAP3K9 HSP90AB1

2.72e-05138113593497c0a5d5e54006653b2dedc7a7041e1a613e6
ToppCellfacs-Heart-Unknown-3m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA1 GRID1 COL24A1 TEX26 TNFSF15

3.11e-051421135759fbbd15b4fb313bd6269b7f087edafebd530ef
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF729 PDE1A LAMA1 ANGPTL8 ASPRV1

4.45e-0515311350307f10e772021ae68a42690634df458672a6df9
ToppCelltumor_Lymph_Node_/_Brain-Myeloid_cells-pDCs|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

DCK WDFY4 COL24A1 SULF2 ZNF43

5.18e-0515811352af7beb48272e5368d9ba6b80f08d47ab8556c08
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PDE1A FAM184A LAMA1 RALGPS1 KAZN

5.50e-05160113503b88dc7ad41c6ae443cab7e77ec666340bf432e
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

ZNF280B SMG8 SULF2 MACROD2 MAP3K9

6.93e-0516811352fb2d916eb5000a637240d38e47a9b4f61f9f83f
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L3_THEMIS_PLA2G7|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PLA2G7 COL24A1 SULF2 RAD54B GMPR

7.75e-0517211351d086e00cd549459d70e1d3b468d5ab6379f3bee
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PDE1A FAM184A LAMA1 RALGPS1 KAZN

8.40e-051751135e5467dacf81f1f913b1719931cf1a7331434a7e7
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D122|Adult / Lineage, Cell type, age group and donor

CAPN9 PDE1A FAM184A MACROD2 ACOXL

8.63e-0517611353fee8a367bb9755aca1b7fcc968b08e51b6e9436
ToppCellLPS-IL1RA+antiTNF-Hematopoietic_Meg-Ery|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SPTB DCK DCUN1D1 TALDO1 DCAF12

9.35e-0517911357329b45376a9e9a4fe34d4aa0b33af6dda0a8e3b
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Macroglial-astrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHL1 CAPN9 PLA2G7 ANKRD35 GRM4

9.35e-0517911357ae67e1c09a4ce9b3bcec4c48ee9cf2b1cb4e339
ToppCellLPS-IL1RA+antiTNF-Hematopoietic_Meg-Ery-Erythroid|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SPTB DCK DCUN1D1 TALDO1 DCAF12

9.35e-0517911356e4740f99f66d3e9348fa5057cf1030454819aa8
ToppCellMultiple_Sclerosis-Other-RBC|Multiple_Sclerosis / Disease, Lineage and Cell Type

SPTB DCUN1D1 WDR87 GMPR DCAF12

9.35e-05179113515763dc59ee6186416e203ffbb450ae4608eba59
ToppCellLPS-IL1RA+antiTNF-Hematopoietic_Meg-Ery-Erythroid-Erythroid|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SPTB DCK DCUN1D1 TALDO1 DCAF12

9.35e-051791135ee60ac43fb62c09967a26bbcf9306ac5ea2bdc1e
ToppCell5'-GW_trimst-2-LymphNode-Hematopoietic-Red_blood_cells|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SPTB DCUN1D1 GMPR TALDO1 DCAF12

9.85e-051811135577bf37a6594fad01251d2c66d8ccda8e949b6cf
ToppCell5'-GW_trimst-2-LymphNode-Hematopoietic-Red_blood_cells-RBC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SPTB DCUN1D1 GMPR TALDO1 DCAF12

9.85e-051811135f5dc7a650afe8837cb424981e50ad2c8b18c7c32
ToppCellControl-Epithelial_cells-Airway_club|Control / group, cell type (main and fine annotations)

CHL1 FAM184A SVIL MACROD2 ACOXL

9.85e-051811135c755d23dd9aabc717dc73e2b3fa99a1f751e6507
ToppCellwk_20-22-Hematologic-Meg-ery-Definitive_erythroblast|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

SPTB ATG2A PSME4 GMPR DCAF12

1.01e-0418211350c77ef4556c1d1512ebe9077df858b28f9e38dd5
ToppCellB_cells-ISG-high_B_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

WDFY4 MACROD2 GMPR DDX60L DNAH8

1.04e-041831135dc2b00e920efa1dcc2a6265cd1024e3249c9974f
ToppCellCF-Myeloid-Neutrophil|CF / Disease state, Lineage and Cell class

TBC1D7 ATG2A TG SVIL DDX60L

1.04e-041831135da43827952e6fdee2ce94648c316182f272b321c
ToppCelldroplet-Lung-21m-Hematologic-myeloid-alveolar_macrophage-alveolar_macrophage|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ACOT1 ARHGAP39 SULF2 GMPR ATP13A3

1.06e-04184113515ea746c77785120f69f9ab370fb7eb9b70692f8
ToppCelldroplet-Lung-21m-Hematologic-myeloid-alveolar_macrophage|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ACOT1 ARHGAP39 SULF2 GMPR ATP13A3

1.06e-041841135bd5e8fc453a6393b8778734a2c3c2f1281769bcd
ToppCellFetal_29-31_weeks-Immune-enucleated_erythrocyte-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SPTB DCUN1D1 GMPR TALDO1 DCAF12

1.09e-041851135c4bf3ac684c1a8876b51f7af4d3a62dc47e961ee
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Adult / Lineage, Cell type, age group and donor

CAPN9 PDE1A FAM184A MACROD2 ACOXL

1.09e-041851135673f0c688ae6984bc8027df2da335787924f4137
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m-Macroglial-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHL1 SPTB MCAM ARHGAP39 PPP2R2C

1.09e-04185113511c147f3f5570c4761d2bcff3bad28146b4a5861
ToppCelldroplet-Limb_Muscle-nan-3m-Macroglial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHL1 PDE1A TBC1D7 MCAM STRIP1

1.09e-041851135554c5d812197fbf66bf279fcc953277e926ade15
ToppCelldroplet-Lung-nan-21m-Myeloid-Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACOT1 ARHGAP39 SULF2 GMPR ATP13A3

1.12e-041861135f1aa0c58336d23bcbe52a59e7af954d20085bdb6
ToppCellLPS_only-Hematopoietic_Meg-Ery-Erythroid-Erythroid|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SPTB DCK DCUN1D1 GMPR DCAF12

1.12e-041861135e5014443e9d6e25943308483e20d48b776ae5373
ToppCelldroplet-Lung-nan-21m-Myeloid-alveolar_macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACOT1 ARHGAP39 SULF2 GMPR ATP13A3

1.12e-0418611358f77e552e613b6e124443c7f6ef5c1316a5ff8db
ToppCellLPS_only-Hematopoietic_Meg-Ery-Erythroid|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SPTB DCK DCUN1D1 GMPR DCAF12

1.12e-041861135affc246a1091e44dc85a5e237c778a7541d5a2b4
ToppCellLPS_only-Hematopoietic_Meg-Ery|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SPTB DCK DCUN1D1 GMPR DCAF12

1.12e-04186113540d1e15402fdfb3b5ae850a2070cd4b68fda3159
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1|TCGA-Pancreas / Sample_Type by Project: Shred V9

STAG1 USP8 DCUN1D1 LTN1 TNFSF15

1.12e-04186113503db813598b67b1e08f759758a1c2023396921fa
ToppCellPND03-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FAM184A ACOT1 USP8 IL33 ACOXL

1.15e-0418711356ab51e17a7782c2ae6394cad813dc3a2cde70c89
ToppCellPCW_10-12-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

FAM184A LAMA1 MACROD2 MAP3K9 ACOXL

1.15e-041871135db2974e2e87ac9f1c2407a371d5ed89af09fc9b7
ToppCellPND03-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FAM184A ACOT1 USP8 IL33 ACOXL

1.15e-041871135e176b5b051690f840f3b12c8f7c4cc10cbe2bbae
ToppCell5'-GW_trimst-2-SmallIntestine-Hematopoietic-Red_blood_cells|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SPTB DCUN1D1 GMPR TALDO1 DCAF12

1.18e-041881135f81099b5b3f1f85a28445bc663efcf73baccb2be
ToppCell5'-GW_trimst-2-SmallIntestine-Hematopoietic-Red_blood_cells-RBC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SPTB DCUN1D1 GMPR TALDO1 DCAF12

1.18e-04188113505b3ade422beeb3db73d350fe192c21bfcfef188
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PDE1A FAM184A LAMA1 RALGPS1 KAZN

1.24e-041901135b94df372bc08de11585b2467dba8c8fffff5cd92
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PDE1A FAM184A LAMA1 RALGPS1 KAZN

1.24e-0419011353dcadabbefe0128a5f30ab51234f049ab4d870c6
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CHL1 EML6 LAMA1 LIPG KAZN

1.27e-041911135d0e9afe7b6334dd515d3e68892efdc76347a55e5
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CHL1 PDE1A SVIL MACROD2 KAZN

1.27e-0419111355a67ff17fb4b9eff641176dff07830c9cd73754e
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PDE1A LAMA1 SVIL MACROD2 KAZN

1.27e-0419111359032aa974aa1b7b1095b8d1b58dcb087358a5001
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CHL1 PDE1A SVIL MACROD2 KAZN

1.27e-04191113555ab2854a02cdcfc395e49870ccb7290b5e5471d
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PDE1A LAMA1 SVIL MACROD2 KAZN

1.27e-0419111355717809a1476c20f65bce722c5a57cff92ee0d7a
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PDE1A FAM184A LAMA1 RALGPS1 KAZN

1.30e-041921135562df5e87038c500dd3a003fe5374cb31946b145
ToppCellNS-moderate-d_0-4|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CHL1 FAM184A DYNC2H1 EFHB DNAH9

1.33e-041931135ea345d34440b25f65358a53dc72831998d1c3620
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CHL1 PDE1A SVIL MACROD2 KAZN

1.33e-041931135f42a0f02ed00fe1bb833ff0a0640d9131bca89bd
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CHL1 PDE1A SVIL MACROD2 KAZN

1.33e-04193113542df7ed37d11fb542b4d1d714b6f87ae8e1396a6
ToppCell343B-Endothelial_cells-Endothelial-B_(Artery)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

CHL1 PPP2R2A LIPG ATP13A3 IL33

1.36e-041941135582db7f7fa9aa08027ae18ed607945b5d1dc908a
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CHL1 PDE1A SVIL MACROD2 KAZN

1.36e-041941135e577d9e88390b36b5a09b97fe1026089892275a3
ToppCelldroplet-Lung-LUNG-1m-Myeloid-Proliferating_Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DCK SULF2 RAD54B GMPR ATP13A3

1.36e-041941135effd38e51062b225ecabc7e1c50154e65495d559
ToppCellPCW_13-14-Epithelial-Epithelial_alveolar-distal-epi_SFTPC^high_distal_(9)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

FAM184A LAMA1 MACROD2 MAP3K9 ACOXL

1.36e-041941135c47fc3f716ab091a39c20d7639ac783029589ee5
ToppCell343B-Endothelial_cells-Endothelial-B_(Artery)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

CHL1 PPP2R2A LIPG ATP13A3 IL33

1.36e-041941135bda89111386398a072b70e8153b2a762298a047a
ToppCellCOVID-19-Heart-Fib_1|Heart / Disease (COVID-19 only), tissue and cell type

DYNC2H1 GASK1B UNC5C KAZN IL33

1.40e-041951135f423baa36ac7cdc383c033e35a7d17e6bf913323
ToppCellPCW_10-12-Epithelial-Epithelial_proliferating-epi_proliferating3_(5)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

FAM184A LAMA1 MACROD2 MAP3K9 ACOXL

1.40e-04195113598dd3b7d5ef587825dac052dea4d4ff883f6d4d6
ToppCellPCW_10-12-Epithelial-Epithelial_proliferating|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

FAM184A LAMA1 MACROD2 MAP3K9 ACOXL

1.40e-041951135ce1ba5911e8a6ddb07434acc37147c38e94245ff
ToppCellTracheal-10x3prime_v2-Epithelial-Epi_submucosal-gland-SMG_Duct|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

ZNF280B URB2 SIX6 MAP3K9 ASPRV1

1.40e-041951135fdbb4abc0c79a6aeace71bfa5a5c5576ca39d758
ToppCellRV-02._Fibroblast_II|World / Chamber and Cluster_Paper

STAG1 DYNC2H1 GASK1B UNC5C KAZN

1.40e-041951135ce90b30dcdb56d4cd925cdb79fd9d7cefd998f48
ToppCellPCW_10-12-Epithelial-Epithelial_alveolar-distal|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

FAM184A LAMA1 MACROD2 MAP3K9 ACOXL

1.43e-0419611350a34a0009f479384f1994c6f977f942699a132c8
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Deep_Layer-37|World / Primary Cells by Cluster

CHL1 PDE1A SYT6 COL24A1 PPP2R2C

1.46e-04197113500d756bc0231e1b3b88430214338c1059cb11106
ToppCellPCW_10-12-Epithelial-Epithelial_alveolar-distal-epi_SFTPC^high_distal_(9)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

FAM184A LAMA1 MACROD2 MAP3K9 ACOXL

1.46e-04197113522b26bac3a99b20c73bfa6e6f81026d064eaa9e8
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

SYT6 COL24A1 HECTD2 UNC5C KAZN

1.46e-0419711350034bae02ee7fcfea520d453ca3c842ab6963b12
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

SYT6 COL24A1 HECTD2 UNC5C KAZN

1.46e-04197113511a4c417f035e554431a8f03be13b5eefa3530c0
ToppCellControl_saline-Hematopoietic_Erythro-Megakary-Erythro-Mega-Erythroid|Control_saline / Treatment groups by lineage, cell group, cell type

SPTB DCUN1D1 PSME4 TALDO1 DCAF12

1.50e-041981135dd80fd9671ee863aebcf4c1023d3e004cc2ee709
ToppCellBiopsy_IPF-Immune-pDCs|Biopsy_IPF / Sample group, Lineage and Cell type

DCK WDFY4 COL24A1 SULF2 EIF2AK4

1.50e-041981135aa8943e6796f619406056cf763b751fe9a9a3e0c
ToppCellCOVID-19-COVID-19_Severe-Myeloid-pDC|COVID-19_Severe / Disease, condition lineage and cell class

DCK WDFY4 COL24A1 SULF2 EIF2AK4

1.50e-041981135033ed362333e1d33f2aeea8da5865d2228d154dc
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

CHL1 MYCBP2 DYNC2H1 LAMA1 UNC5C

1.53e-041991135a7dd94b172c973a131a6792f8ccd9bfe44d984ac
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-DC-DC3-E|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

WDFY4 COL24A1 SULF2 EIF2AK4 TNFSF15

1.53e-0419911357271dbeca9aa838b88ad44d00059263a29c0316b
ToppCellMS-Multiple_Sclerosis-Others-RBC|Multiple_Sclerosis / Disease, condition lineage and cell class

SPTB DCUN1D1 GMPR TALDO1 DCAF12

1.53e-041991135b9e7549f67bc33284bacf9a160b3916651659809
ToppCellBronchial-NucSeq-Stromal-Fibroblastic-Fibro_perichondrial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DYNC2H1 TRPC1 COL24A1 UNC5C KAZN

1.53e-041991135abd6117f8a3d7e798d8471c16d97b34aaf50fc9c
ToppCellBronchial-NucSeq-Stromal-Pericyte|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SPTB MCAM GRID1 ANGPTL8 UNC5C

1.53e-041991135854628ce91068093c14bd4d45ba38c41469f3549
Diseasedevelopmental and epileptic encephalopathy 87 (implicated_via_orthology)

CDK8 CDK19

1.38e-0521102DOID:0112221 (implicated_via_orthology)
DiseaseAlzheimer's disease (implicated_via_orthology)

RCOR2 RCOR1 RCOR3 IL33

6.20e-05571104DOID:10652 (implicated_via_orthology)
DiseaseJeune thoracic dystrophy

DYNC2H1 WDR19

8.22e-0541102cv:C0265275
Diseaseintellectual disability (implicated_via_orthology)

CAPN9 ZNF280D ZNF280B RYK

1.81e-04751104DOID:1059 (implicated_via_orthology)
DiseaseImmediate hypersensitivity

PLA2G7 IL33

3.80e-0481102C0020523
Diseaseurate measurement, bone density

GRID1 DCK FADS2B TG ALKBH3 EIF2AK4 KAZN DNAH8 DNAH9

5.26e-046191109EFO_0003923, EFO_0004531
Diseasereticulocyte count

ATR SPTB GRAMD1A EML6 RCOR1 DCUN1D1 LTN1 GMPR EIF2AK4 ASPRV1 DCAF12 HSP90AB1

5.31e-04104511012EFO_0007986
DiseaseJeune thoracic dystrophy

DYNC2H1 WDR19

7.41e-04111102C0265275
DiseasePathological accumulation of air in tissues

PPP2R2A PPP2R2C

8.87e-04121102C0013990
Diseaseautosomal dominant cerebellar ataxia (implicated_via_orthology)

PPP2R2A PPP2R2C

8.87e-04121102DOID:1441 (implicated_via_orthology)
Diseasenon-alcoholic fatty liver disease, cirrhosis of liver

SVIL MACROD2 DDX60L

1.03e-03531103EFO_0001422, EFO_0003095
Diseaseglycodeoxycholate measurement

SVIL IL33

1.22e-03141102EFO_0010493
Disease2-oxo-hept-3-ene-1,7-dioate hydratase activity

EIF2AK4 ATP13A3

1.22e-03141102C1150929
DiseaseFamilial primary pulmonary hypertension

EIF2AK4 ATP13A3

1.81e-03171102C0340543
Diseaseradiation-induced disorder

TRPC1 PPP2R2A MACROD2

2.03e-03671103EFO_0009565
Diseasefasting blood insulin measurement

SPTB URB2 DCUN1D1

2.21e-03691103EFO_0004466
DiseaseChronic myeloproliferative disorder

ATR LIG4

2.26e-03191102C1292778
DiseaseInfiltrating duct carcinoma of female breast

ATR RPS6KC1

2.76e-03211102C3165106
DiseaseSeckel syndrome

ATR LIG4

3.03e-03221102C0265202
Diseaseinterleukin 10 measurement

DYNC2H1 MACROD2 HSP90AB1

3.13e-03781103EFO_0004750
Diseaseleptin measurement

SPTB DCUN1D1 DNAH8

3.48e-03811103EFO_0005000

Protein segments in the cluster

PeptideGeneStartEntry
ALHWEHELGLAFTKN

TNFSF15

116

O95150
DKLKLAHFAWISHQC

URB2

21

Q14146
KHHLEFEKQRNDSWE

ZNF280B

326

Q86YH2
KHHLELEKQSSESWE

ZNF280D

341

Q6N043
VDAWKQLQTFFHKHL

ACOT1

396

Q86TX2
FTKKILHTAWHPAEN

PPP2R2C

411

Q9Y2T4
FLKLTSIKDHQWHIQ

ARL5A

141

Q9Y689
EHDLWHIIKFHRASK

CDK19

101

Q9BWU1
HAKQKSVISWLLNHD

EIF2AK4

971

Q9P2K8
DSLDFNKKILHTAWH

PPP2R2A

411

P63151
IALAHRKLESKLTWH

ATP13A3

686

Q9H7F0
WEDNFHCKLSRHALK

GRM4

366

Q14833
TWKNKEHHLSDREFV

ALKBH3

41

Q96Q83
LLSDKKLDEWHEHTA

CMTR2

76

Q8IYT2
KLDEWHEHTAFTNKA

CMTR2

81

Q8IYT2
HEAWLIHKTTKLHFE

DGUOK

226

Q16854
IKKWASHHQINDASR

TENT2

311

Q6PIY7
VLKAHADKQSHILWA

ANGPTL8

151

Q6UXH0
DALHYALHTQDKALW

ANKRD35

221

Q8N283
TWELHNKHLFENLVF

FAM193A

66

P78312
KFLDLWNKFLLEHHK

DCUN1D1

191

Q96GG9
NEAHSKTLEELAWKH

FAM184A

476

Q8NB25
PDAHKDHALKWRSDS

ATG2A

1921

Q2TAZ0
HTFESWHSLALAKGK

GRAMD1A

641

Q96CP6
ITHHADNTLKSFCKW

ADAMTS7

306

Q9UKP4
KKEDFFHAWNSCLHH

ACOXL

461

Q9NUZ1
LFWHKHNIEKSLADL

RCOR1

171

Q9UKL0
LLWHKHDVEKSLADL

RCOR2

111

Q8IZ40
FWHKHNIEKSLADLP

RCOR3

66

Q9P2K3
LKQWKHFSGDHLNLT

RAD54B

871

Q9Y620
ETDIENWASKHFNKH

ARHGAP39

691

Q9C0H5
AILWHKHLDDACKSN

RALGPS1

531

Q5JS13
KESTFLHLSALWLKN

LTN1

891

O94822
ALKDSDLLHWKHSLS

ANAPC5

401

Q9UJX4
KSLTNDWEDHLAVKH

HSP90AB1

306

P08238
SALAHLLQAKSEFWH

PAQR7

121

Q86WK9
SLSKAAELDHHWVAK

KAZN

516

Q674X7
DSHLKHSLKLSWSKD

CHL1

541

O00533
HKELWQIHKNLFRHS

RPS6KC1

61

Q96S38
VEADHHFLVHWFKKL

HECTD2

261

Q5U5R9
FKQKTSDELLHWHAQ

DDX60L

476

Q5H9U9
KFLDLWNTFLMEHHK

DCUN1D2

191

Q6PH85
ILHAADISHPAKSWK

PDE1A

361

P54750
WADILNHKSKHVEEA

DNAH8

756

Q96JB1
WLHKLVSALHTREKD

LIPG

101

Q9Y5X9
FVKKLEHSWKALVHD

PIP5K1A

411

Q99755
FLQKHLGLHKDFDQW

PLA2G7

391

Q13093
KLEHSWKALIHDGDT

PIPSL

361

A2A3N6
QHDAGHLSIFRKSKW

FADS2B

216

A8MWK0
HLSIFRKSKWNHVVH

FADS2B

221

A8MWK0
AWELAQFIHHTSKKA

SMPD2

156

O60906
HHEWSKMALFDFLLQ

GASK1B

361

Q6UWH4
LVEKHLFTVHDWEKN

DYNC2H1

871

Q8NCM8
DHLTQWARHKFQALK

ATR

1586

Q13535
DFWLHANNKEHSVEL

IL33

191

O95760
VHHKLNSELWKPESF

KDM3A

981

Q9Y4C1
HDLLVHKAVAKWTAE

BFAR

171

Q9NZS9
EFLDSWRKFHDALHK

LIG4

41

P49917
FHLWKAENTLSKLLS

DCAF12

276

Q5T6F0
VASALHKLHQDLWKT

CEP250

1241

Q9BV73
AIDIIKSTHDHWKAL

PPA1

216

Q15181
EEFENVWNLASKKHH

EFHB

791

Q8N7U6
ANAFHRKLEDRKWHS

GRID1

331

Q9ULK0
KHESWLLHRTLKTNF

DCK

211

P27707
WKDHFLIRLVAKAHT

EML6

1581

Q6ZMW3
KRWSLLFKQHLVDHV

DNAH9

1101

Q9NYC9
IHKHYSLDDWKLFAT

GMPR

76

P36959
HSADHNEFWSALLEK

CAPN9

161

O14815
EHDLWHIIKFHRASK

CDK8

101

P49336
HIFKWITAHAASRIK

RNF103

201

O00237
TNFLHFTWHAKSKVE

RYK

106

P34925
KDSFHCLQDNWKHEI

MAP3K9

416

P80192
IISHEKKAHDNWLAA

MIA2

1061

Q96PC5
NLSHVDWFSVHKEKR

MCAM

56

P43121
ALNTIKEWLAKNHHE

MACROD2

201

A1Z1Q3
HEFWKHQEKLQCLSL

SMG8

186

Q8ND04
AHWHSLVEVKKSFKE

SYT6

491

Q5T7P8
EGINTHTHAAKDFWK

SVIL

1521

O95425
SWKVHKESDSHQFRV

RIC8B

241

Q9NVN3
DHQDKLLLWSAKIRH

LAMA1

1836

P25391
HLFWANKLIQASEHS

SPATA32

156

Q96LK8
DKKWTELDTNQHRTH

STRIP1

111

Q5VSL9
KESHAKLQALWLEAH

SIX6

81

O95475
WSLKFKQSDHQFLHQ

MYCBP2

3681

O75592
LQHWDSALQLAKHLA

WDR19

756

Q8NEZ3
SDAIVSKAIDLWHKH

TBC1D7

271

Q9P0N9
KKNQEILWILHTHSF

MROH2B

1496

Q7Z745
LNHWDHITKLRFLKE

ASPRV1

126

Q53RT3
KIQDGSWHKATFLFH

COL24A1

1666

Q17RW2
HKSFQLIANHEDKEW

TRPC1

646

P48995
TFKWFSDLTNHKRIH

ZNF727

376

A8MUV8
GKAFSWKSHLIEHQR

ZNF189

266

O75820
AFKWSSSLNEHKRIH

ZNF718

291

Q3SXZ3
QHLSHTFLDKKDWTG

ZNF815P

31

A8K554
HHLDSQSRWSKVKDK

TCERG1

806

O14776
IKFKHLEEAFTSEHW

STT3B

751

Q8TCJ2
KALESDFVSANLHHW

WDFY4

2741

Q6ZS81
KVFSLWALHAEHQKI

ZNF137P

191

P52743
STELHSNEKWFHGKL

PLCG1

541

P19174
KRLTSFHNAHDLTKW

STAG1

696

Q8WVM7
SWKDGLAFNALIHKH

SPTB

201

P11277
SYDEARNLHNKWLKH

SPTB

1301

P11277
KWLKHQAFVAELASH

SPTB

1311

P11277
SHKHEFDSRWKSFNL

PSME4

906

Q14997
AFKWSSKLTEHKLTH

ZNF43

406

P17038
FNWSSKLKDHQRVHT

ZNF112

506

Q9UJU3
IWLHKDIDAFAQVFH

YTHDC2

476

Q9H6S0
KIHLDEKSFRWLHNE

TALDO1

286

P37837
KSHKSHLNEDIFLWT

TEX26

96

Q8N6G2
EAHKTSLSSWKHDQD

UNQ5830/PRO19650/PRO19816

21

Q6UY13
AFGWSTDLNKHKIIH

ZNF732

426

B4DXR9
SLSSQKHWLFKHLFS

TG

1871

P01266
IHSKAFHASFELWQL

UHRF1BP1

136

Q6BDS2
HDIAHSLWKSKLLAK

UNC5C

746

O95185
LASKGNLEWLHLAKH

WDR87

2556

Q6ZQQ6
LDDFKAAEHAWQKHK

USP8

901

P40818
DLYKSLQAWKDHKLH

SULF2

616

Q8IWU5
AFKWSSKLTEHKVIH

ZNF729

1056

A6NN14
WFSDLAKHKIIHTGD

ZNF736

296

B4DX44