Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ATP hydrolysis activity	TDRD9 DNAH7 ABCA10 ABCA9 RUVBL1 ABCA5 SMC3 ATP1A1 ATP1A3 TOR3A POLQ	1.94e-04	441	134	11	GO:0016887
GeneOntologyMolecularFunction	lipid transporter activity	APOB ABCA10 ABCA9 PLEKHA8P1 ABCA5 PRELID2 MTTP	3.62e-04	196	134	7	GO:0005319
GeneOntologyMolecularFunction	pyrophosphatase activity	TDRD9 APTX DNAH7 ABCA10 ABCA9 RUVBL1 ABCA5 SMC3 PPA2 GNL2 ATP1A1 ATP1A3 TOR3A ATL2 POLQ	5.16e-04	839	134	15	GO:0016462
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides	TDRD9 APTX DNAH7 ABCA10 ABCA9 RUVBL1 ABCA5 SMC3 PPA2 GNL2 ATP1A1 ATP1A3 TOR3A ATL2 POLQ	5.23e-04	840	134	15	GO:0016817
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	TDRD9 APTX DNAH7 ABCA10 ABCA9 RUVBL1 ABCA5 SMC3 PPA2 GNL2 ATP1A1 ATP1A3 TOR3A ATL2 POLQ	5.23e-04	840	134	15	GO:0016818
GeneOntologyMolecularFunction	lipid transfer activity	APOB PLEKHA8P1 PRELID2 MTTP	5.82e-04	57	134	4	GO:0120013
GeneOntologyMolecularFunction	phospholipid transfer activity	PLEKHA8P1 PRELID2 MTTP	6.86e-04	26	134	3	GO:0120014
GeneOntologyMolecularFunction	glycosyltransferase activity	DPY19L2 DPY19L1 PARP8 PARP1 ST8SIA6 UGT8 UGGT2 DPY19L2P2	7.38e-04	288	134	8	GO:0016757
GeneOntologyMolecularFunction	ATPase-coupled transmembrane transporter activity	ABCA10 ABCA9 ABCA5 ATP1A1 ATP1A3	8.44e-04	109	134	5	GO:0042626
GeneOntologyMolecularFunction	mannosyltransferase activity	DPY19L2 DPY19L1 DPY19L2P2	8.56e-04	28	134	3	GO:0000030
GeneOntologyMolecularFunction	ATP-dependent activity	TDRD9 MYO1B DNAH7 ABCA10 ABCA9 RUVBL1 ABCA5 SMC3 ATP1A1 ATP1A3 TOR3A POLQ	8.93e-04	614	134	12	GO:0140657
GeneOntologyMolecularFunction	ceramide 1-phosphate transfer activity	PLEKHA8P1 MTTP	9.18e-04	7	134	2	GO:1902388
GeneOntologyMolecularFunction	steroid hormone binding	ATP1A1 ATP1A3	9.18e-04	7	134	2	GO:1990239
GeneOntologyMolecularFunction	ceramide transfer activity	PLEKHA8P1 MTTP	1.22e-03	8	134	2	GO:0120017
GeneOntologyBiologicalProcess	peptidyl-tryptophan modification	DPY19L2 DPY19L1 DPY19L2P2	5.05e-06	6	132	3	GO:0018211
GeneOntologyBiologicalProcess	protein C-linked glycosylation via tryptophan	DPY19L2 DPY19L1 DPY19L2P2	5.05e-06	6	132	3	GO:0018317
GeneOntologyBiologicalProcess	protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan	DPY19L2 DPY19L1 DPY19L2P2	5.05e-06	6	132	3	GO:0018406
GeneOntologyBiologicalProcess	protein C-linked glycosylation	DPY19L2 DPY19L1 DPY19L2P2	5.05e-06	6	132	3	GO:0018103
GeneOntologyBiologicalProcess	habituation	SHANK1 DGKI ATP1A3	1.40e-05	8	132	3	GO:0046959
GeneOntologyBiologicalProcess	nonassociative learning	SHANK1 DGKI ATP1A3	6.99e-05	13	132	3	GO:0046958
GeneOntologyBiologicalProcess	response to environmental enrichment	ATP1A3 ALK	1.21e-04	3	132	2	GO:0090648
Domain	ARM-type_fold	USP34 GBF1 APOB HUWE1 TRRAP RYR3 NF1 UTP20 CAB39L NUP188 EIF4G3	2.55e-05	339	130	11	IPR016024
Domain	Vitellinogen_b-sht_N	APOB MTTP	4.81e-05	2	130	2	IPR015816
Domain	Lipid_transp_b-sht_shell	APOB MTTP	4.81e-05	2	130	2	IPR015819
Domain	-	APOB MTTP	4.81e-05	2	130	2	2.30.230.10
Domain	VITELLOGENIN	APOB MTTP	4.81e-05	2	130	2	PS51211
Domain	LPD_N	APOB MTTP	4.81e-05	2	130	2	SM00638
Domain	Lipid_transpt_N	APOB MTTP	4.81e-05	2	130	2	IPR001747
Domain	-	APOB MTTP	4.81e-05	2	130	2	1.25.10.20
Domain	Vitellogenin_N	APOB MTTP	4.81e-05	2	130	2	PF01347
Domain	ABC_A	ABCA10 ABCA9 ABCA5	6.92e-05	12	130	3	IPR026082
Domain	Vitellinogen_superhlx	APOB MTTP	1.44e-04	3	130	2	IPR011030
Domain	FAS1	STAB2 POSTN	2.86e-04	4	130	2	SM00554
Domain	FAS1_domain	STAB2 POSTN	2.86e-04	4	130	2	IPR000782
Domain	Dpy19	DPY19L2 DPY19L1	2.86e-04	4	130	2	PF10034
Domain	Dpy-19/Dpy-19-like	DPY19L2 DPY19L1	2.86e-04	4	130	2	IPR018732
Domain	-	STAB2 POSTN	2.86e-04	4	130	2	2.30.180.10
Domain	FAS1	STAB2 POSTN	2.86e-04	4	130	2	PS50213
Domain	Fasciclin	STAB2 POSTN	2.86e-04	4	130	2	PF02469
Domain	P-type_ATPase_IIC	ATP1A1 ATP1A3	7.08e-04	6	130	2	IPR005775
Domain	USP_CS	USP34 USP25 USP8 USP15	1.16e-03	66	130	4	IPR018200
Domain	USP_1	USP34 USP25 USP8 USP15	1.44e-03	70	130	4	PS00972
Domain	UCH	USP34 USP25 USP8 USP15	1.52e-03	71	130	4	PF00443
Domain	USP_2	USP34 USP25 USP8 USP15	1.52e-03	71	130	4	PS00973
Domain	USP_3	USP34 USP25 USP8 USP15	1.60e-03	72	130	4	PS50235
Domain	USP_dom	USP34 USP25 USP8 USP15	1.60e-03	72	130	4	IPR028889
Domain	Peptidase_C19_UCH	USP34 USP25 USP8 USP15	1.60e-03	72	130	4	IPR001394
Domain	AAA	DNAH7 ABCA10 ABCA9 RUVBL1 ABCA5	3.36e-03	144	130	5	SM00382
Domain	AAA+_ATPase	DNAH7 ABCA10 ABCA9 RUVBL1 ABCA5	3.36e-03	144	130	5	IPR003593
Domain	ConA-like_dom	FAT4 BTNL8 LAMA4 RYR3 LMAN2L ALK	4.34e-03	219	130	6	IPR013320
Domain	ABC_tran	ABCA10 ABCA9 ABCA5	4.53e-03	48	130	3	PF00005
Domain	ABC_TRANSPORTER_2	ABCA10 ABCA9 ABCA5	4.53e-03	48	130	3	PS50893
Domain	ABC_TRANSPORTER_1	ABCA10 ABCA9 ABCA5	4.81e-03	49	130	3	PS00211
Domain	ABC_transporter-like	ABCA10 ABCA9 ABCA5	5.09e-03	50	130	3	IPR003439
Domain	ATPase_P-typ_TM_dom	ATP1A1 ATP1A3	5.41e-03	16	130	2	IPR023298
Domain	-	ATP1A1 ATP1A3	5.41e-03	16	130	2	1.20.1110.10
Domain	-	ADCY10 TDRD9 DNAH7 ABCA10 ABCA9 RUVBL1 ABCA5 SMC3 GNL2 TOR3A ATL2 POLQ	5.89e-03	746	130	12	3.40.50.300
Domain	Poly(ADP-ribose)pol_cat_dom	PARP8 PARP1	6.11e-03	17	130	2	IPR012317
Domain	PARP_CATALYTIC	PARP8 PARP1	6.11e-03	17	130	2	PS51059
Domain	ATPase_P-typ_cation-transptr_C	ATP1A1 ATP1A3	6.11e-03	17	130	2	IPR006068
Domain	Cation_ATPase_C	ATP1A1 ATP1A3	6.11e-03	17	130	2	PF00689
Domain	PARP	PARP8 PARP1	6.11e-03	17	130	2	PF00644
Domain	-	PARP8 PARP1	6.11e-03	17	130	2	3.90.228.10
Domain	P-loop_NTPase	ADCY10 TDRD9 MYO1B DNAH7 ABCA10 ABCA9 RUVBL1 ABCA5 SMC3 GNL2 TOR3A ATL2 POLQ	6.23e-03	848	130	13	IPR027417
Domain	Cation_ATPase_N	ATP1A1 ATP1A3	6.84e-03	18	130	2	PF00690
Domain	Cation_ATPase_N	ATP1A1 ATP1A3	6.84e-03	18	130	2	SM00831
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	USP34 SRRM1 ZC3H14 MAP1B NSD1 MYO1B HUWE1 TRRAP PBRM1 NF1 PHF3 GNL2 UTP20 NUP188 ATP1A1 EIF4G3 HDAC2	7.55e-10	653	135	17	22586326
Pubmed	Dpy19l1, a multi-transmembrane protein, regulates the radial migration of glutamatergic neurons in the developing cerebral cortex.	ZC3H14 DPY19L2 DPY19L1 DCTN4 DPY19L2P2	1.21e-08	20	135	5	22028030
Pubmed	The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.	SHANK1 USP34 GBF1 DPY19L1 C6orf89 GDE1 CCNT2 PARP1 NAA25 CYFIP1 PBRM1 LMAN2L PHF3 UGT8 UQCC1 NUP188 ATP1A1 ATL2 GNPAT	2.21e-07	1203	135	19	29180619
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	ZC3H14 TES MAP1B NSD1 HUWE1 TRRAP BRAP CYFIP1 RUVBL1 PHF3 STEEP1 USP15 HDAC2	2.49e-07	549	135	13	38280479
Pubmed	KAP1 facilitates reinstatement of heterochromatin after DNA replication.	TES MAP1B HUWE1 TRRAP CYFIP1 STXBP1 RUVBL1 SMC3 CCDC47 UTP20 NUP188 ATP1A1 DCTN4 EIF4G3	6.84e-07	704	135	14	29955894
Pubmed	A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome.	USP34 SRRM1 GBF1 APOB DNAH7 PARP1 NF1 STYX KIAA1217 ATP1A1 ALK	8.19e-07	420	135	11	28065597
Pubmed	Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.	SRRM1 DNAJC19 ICE2 SPG11 TRRAP TSEN2 CCNT2 PARP1 SERPINB6 PBRM1 NF1 SMC3 FBXO42 STEEP1 UQCC1 NUP188 ATP1A3 ATL2 PPTC7	9.64e-07	1327	135	19	32694731
Pubmed	Virus-Host Interactome and Proteomic Survey Reveal Potential Virulence Factors Influencing SARS-CoV-2 Pathogenesis.	EXOC6 TES DPY19L2 SERPINB6 LMAN2L UGT8 UTP20 UGGT2 PIBF1	1.86e-06	285	135	9	32838362
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	SRRM1 ZC3H14 MAP1B MYO1B HUWE1 TRRAP PARP1 PBRM1 NF1 RUVBL1 SMC3 GNL2 UTP20 NUP188 ATP1A1 HDAC2	2.48e-06	1024	135	16	24711643
Pubmed	Large-scale mapping of human protein-protein interactions by mass spectrometry.	SRRM1 GBF1 MYO1B RAB11FIP1 TRRAP USP8 NAA25 RUVBL1 SMC3 CCDC47 STEEP1 GNL2 CAB39L NUP188 EIF4G3 POLQ USP15 MOB4	2.57e-06	1284	135	18	17353931
Pubmed	Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.	USP34 SRRM1 RIPK1 UACA MAP1B DPY19L1 MYO1B TRRAP CCNT2 CYFIP1 CCDC198 NF1 NUP188 DCTN4 HDAC2	2.74e-06	910	135	15	36736316
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	SRRM1 MAP1B PARP8 MYO1B SPG11 APOB DCC NEB USP8 PARP1 STXBP1 CCDC47 MTTP UGGT2 ATP1A1 ATP1A3 EIF4G3 POLQ HDAC2	3.25e-06	1442	135	19	35575683
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	USP34 FAT4 MAP1B DPY19L1 LAMA4 GDE1 LMAN2L NF1 RUVBL1 CCDC47 UGT8 UTP20 UGGT2 ATP1A1 TOR3A EIF4G3 USP15	4.40e-06	1201	135	17	35696571
Pubmed	Nuclear lamina genetic variants, including a truncated LAP2, in twins and siblings with nonalcoholic fatty liver disease.	SRRM1 MYO1B APOB HUWE1 PARP1 RUVBL1 MTTP ATP1A1	5.39e-06	244	135	8	28902428
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	SHANK1 UACA SH3GL2 NSD1 HUWE1 PARP1 CYFIP1 PBRM1 NF1 KCNB1 KIAA1217 DGKI PLCL1 MOB4 HDAC2	5.42e-06	963	135	15	28671696
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	USP34 TES ICE2 SPG11 HUWE1 BRAP USP8 CCDC47 PHF3 GNL2 UGGT2 ATL2 USP15	6.04e-06	733	135	13	34672954
Pubmed	The human ATP-binding cassette (ABC) transporter superfamily.	ABCA10 ABCA9 ABCA5	6.73e-06	10	135	3	11435397
Pubmed	A proteomic analysis of ataxia telangiectasia-mutated (ATM)/ATM-Rad3-related (ATR) substrates identifies the ubiquitin-proteasome system as a regulator for DNA damage checkpoints.	USP34 HUWE1 SMC3	6.73e-06	10	135	3	17478428
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	SRRM1 GBF1 MAP1B EXPH5 PARP8 RAB11FIP1 DNAH7 USP8 NF1 PHF3 KIAA1217 CRYBG3 EIF4G3 PIBF1	7.01e-06	861	135	14	36931259
Pubmed	A promiscuous biotin ligase fusion protein identifies proximal and interacting proteins in mammalian cells.	PARP1 RUVBL1 CCDC47 STEEP1 GNL2 USP15	8.15e-06	121	135	6	22412018
Pubmed	Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.	TES RIPK1 UACA DNAJC19 USP25 LMAN2L PRIM1 GNL2 UTP20 UGGT2 UQCC1 PIBF1 HDAC2	8.17e-06	754	135	13	33060197
Pubmed	Combinatorial CRISPR-Cas9 screens for de novo mapping of genetic interactions.	PARP1 PBRM1 NF1 ALK HDAC2	8.67e-06	71	135	5	28319113
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	HUWE1 TRRAP PARP1 PBRM1 NF1 RUVBL1 PHF3 GNL2 NUP188 USP15	9.15e-06	440	135	10	34244565
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	GBF1 MYO1B APOB HUWE1 PARP1 CYFIP1 PBRM1 NF1 RUVBL1 SMC3 CCDC47 PRIM1 PPA2 GNL2 UTP20 NUP188 ATP1A1 ATL2	1.07e-05	1425	135	18	30948266
Pubmed	Sodium transport is modulated by p38 kinase-dependent cross-talk between ENaC and Na,K-ATPase in collecting duct principal cells.	SCNN1G ATP1A1	1.50e-05	2	135	2	24179170
Pubmed	Human placenta secretes apolipoprotein B-100-containing lipoproteins.	APOB MTTP	1.50e-05	2	135	2	15504742
Pubmed	Molecular cloning of Lyt-3, a membrane glycoprotein marking a subset of mouse T lymphocytes: molecular homology to immunoglobulin and T-cell receptor variable and joining regions.	CD8B CD8B2	1.50e-05	2	135	2	3035575
Pubmed	Molecular characterization of the murine cytotoxic T-cell membrane glycoprotein Ly-3 (CD8).	CD8B CD8B2	1.50e-05	2	135	2	3498943
Pubmed	An immunological role for the CD8 beta-chain.	CD8B CD8B2	1.50e-05	2	135	2	1534146
Pubmed	Microsomal triglyceride transfer protein gene expression and ApoB secretion are inhibited by bitter melon in HepG2 cells.	APOB MTTP	1.50e-05	2	135	2	15795421
Pubmed	Duality of the murine CD8 compartment.	CD8B CD8B2	1.50e-05	2	135	2	24594598
Pubmed	Disruption of T lymphocyte positive and negative selection in mice lacking the CD8 beta chain.	CD8B CD8B2	1.50e-05	2	135	2	7889415
Pubmed	All human Na(+)-K(+)-ATPase alpha-subunit isoforms have a similar affinity for cardiac glycosides.	ATP1A1 ATP1A3	1.50e-05	2	135	2	11546672
Pubmed	AKXD recombinant inbred strains: models for studying the molecular genetic basis of murine lymphomas.	CD8B CD8B2	1.50e-05	2	135	2	3025647
Pubmed	Genetic inhibition of Anaplastic Lymphoma Kinase rescues cognitive impairments in Neurofibromatosis 1 mutant mice.	NF1 ALK	1.50e-05	2	135	2	28057529
Pubmed	Gene transfer of the Ly-3 chain gene of the mouse CD8 molecular complex: co-transfer with the Ly-2 polypeptide gene results in detectable cell surface expression of the Ly-3 antigenic determinants.	CD8B CD8B2	1.50e-05	2	135	2	2452747
Pubmed	Distinct methylation states of the CD8 beta gene in peripheral T cells and intraepithelial lymphocytes.	CD8B CD8B2	1.50e-05	2	135	2	9233619
Pubmed	Properties and expression of Na+/K+-ATPase α-subunit isoforms in the brain of the swamp eel, Monopterus albus, which has unusually high brain ammonia tolerance.	ATP1A1 ATP1A3	1.50e-05	2	135	2	24391932
Pubmed	Stalk region of beta-chain enhances the coreceptor function of CD8.	CD8B CD8B2	1.50e-05	2	135	2	12847256
Pubmed	A deficiency of microsomal triglyceride transfer protein reduces apolipoprotein B secretion.	APOB MTTP	1.50e-05	2	135	2	10713055
Pubmed	Na+/K+ ATPase α1 and α3 isoforms are differentially expressed in α- and γ-motoneurons.	ATP1A1 ATP1A3	1.50e-05	2	135	2	23761886
Pubmed	Transcriptional diversity at the duplicated human CD8 beta loci.	CD8B CD8B2	1.50e-05	2	135	2	8436166
Pubmed	Homozygous MTTP and APOB mutations may lead to hepatic steatosis and fibrosis despite metabolic differences in congenital hypocholesterolemia.	APOB MTTP	1.50e-05	2	135	2	24842304
Pubmed	The family of human Na+,K+-ATPase genes. A partial nucleotide sequence related to the alpha-subunit.	ATP1A1 ATP1A3	1.50e-05	2	135	2	3030810
Pubmed	Structure and expression of the Lyt-3a gene of C.AKR mice.	CD8B CD8B2	1.50e-05	2	135	2	3169881
Pubmed	Microsomal triglyceride transfer protein binding and lipid transfer activities are independent of each other, but both are required for secretion of apolipoprotein B lipoproteins from liver cells.	APOB MTTP	1.50e-05	2	135	2	11358959
Pubmed	Esr, a second locus in the house mouse controlling esterase-5.	CD8B CD8B2	1.50e-05	2	135	2	7103930
Pubmed	Dpy19l2-deficient globozoospermic sperm display altered genome packaging and DNA damage that compromises the initiation of embryo development.	DPY19L2 DPY19L2P2	1.50e-05	2	135	2	25354700
Pubmed	Subcellular localization of phospholipase Cζ in human sperm and its absence in DPY19L2-deficient sperm are consistent with its role in oocyte activation.	DPY19L2 DPY19L2P2	1.50e-05	2	135	2	25354701
Pubmed	Ly-C: a third locus specifying alloantigens expressed only on thymocytes and lymphocytes.	CD8B CD8B2	1.50e-05	2	135	2	5558567
Pubmed	Structure-function analyses of microsomal triglyceride transfer protein missense mutations in abetalipoproteinemia and hypobetalipoproteinemia subjects.	APOB MTTP	1.50e-05	2	135	2	27487388
Pubmed	Cloning and modeling of CD8 beta in the amphibian ambystoma Mexicanum. Evolutionary conserved structures for interactions with major histocompatibility complex (MHC) class I molecules.	CD8B CD8B2	1.50e-05	2	135	2	12034498
Pubmed	Identification of patients with abetalipoproteinemia and homozygous familial hypobetalipoproteinemia in Tunisia.	APOB MTTP	1.50e-05	2	135	2	19056372
Pubmed	Immunohistochemical analyses of alpha1 and alpha3 Na+/K+-ATPase subunit expression in medulloblastomas.	ATP1A1 ATP1A3	1.50e-05	2	135	2	21498719
Pubmed	Recurrent deletions in clonal hematopoiesis are driven by microhomology-mediated end joining.	PARP1 POLQ	1.50e-05	2	135	2	33911081
Pubmed	Kinase-independent role of nuclear RIPK1 in regulating parthanatos through physical interaction with PARP1 upon oxidative stress.	RIPK1 PARP1	1.50e-05	2	135	2	28993228
Pubmed	Relationship between Amphipathic β Structures in the β1 Domain of Apolipoprotein B and the Properties of the Secreted Lipoprotein Particles in McA-RH7777 Cells.	APOB MTTP	1.50e-05	2	135	2	28702990
Pubmed	ALK upregulates POSTN and WNT signaling to drive neuroblastoma.	POSTN ALK	1.50e-05	2	135	2	38451815
Pubmed	Requirement for CD8 beta chain in positive selection of CD8-lineage T cells.	CD8B CD8B2	1.50e-05	2	135	2	8108731
Pubmed	PARP and RIP 1 are required for autophagy induced by 11'-deoxyverticillin A, which precedes caspase-dependent apoptosis.	RIPK1 PARP1	1.50e-05	2	135	2	21460625
Pubmed	A common binding site on the microsomal triglyceride transfer protein for apolipoprotein B and protein disulfide isomerase.	APOB MTTP	1.50e-05	2	135	2	9915855
Pubmed	Murine Ly-3 restriction fragment length polymorphism and transcript size differences.	CD8B CD8B2	1.50e-05	2	135	2	2576243
Pubmed	Pharmacological inhibition of Anaplastic Lymphoma Kinase rescues spatial memory impairments in Neurofibromatosis 1 mutant mice.	NF1 ALK	1.50e-05	2	135	2	28629962
Pubmed	Absence of Dpy19l2, a new inner nuclear membrane protein, causes globozoospermia in mice by preventing the anchoring of the acrosome to the nucleus.	DPY19L2 DPY19L2P2	1.50e-05	2	135	2	22764053
Pubmed	The cytoplasmic domain of CD8 beta regulates Lck kinase activation and CD8 T cell development.	CD8B CD8B2	1.50e-05	2	135	2	9647223
Pubmed	Novel mutations in abetalipoproteinaemia and homozygous familial hypobetalipoproteinaemia.	APOB MTTP	1.50e-05	2	135	2	18027103
Pubmed	The IB-peptide marker and the Ly-3 surface alloantigen: structural studies of a V kappa-region polymorphism and a T-cell marker determined by linked genes.	CD8B CD8B2	1.50e-05	2	135	2	408079
Pubmed	Hypobetalipoproteinemia with an apparently recessive inheritance due to a "de novo" mutation of apolipoprotein B.	APOB MTTP	1.50e-05	2	135	2	14732481
Pubmed	Characterization of the mouse CD8 beta chain-encoding gene promoter region.	CD8B CD8B2	1.50e-05	2	135	2	8781121
Pubmed	Interrogating the Significance of PARP1 Expression and PBRM1 Mutation as Biomarkers for Predicting the Response to Atezolizumab plus Bevacizumab or to Sunitinib in Patients with Clear Cell Renal Cell Carcinoma.	PARP1 PBRM1	1.50e-05	2	135	2	35688666
Pubmed	Microsomal triglyceride transfer protein activity is not required for the initiation of apolipoprotein B-containing lipoprotein assembly in McA-RH7777 cells.	APOB MTTP	1.50e-05	2	135	2	17690102
Pubmed	Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.	USP34 GBF1 DPY19L2 SPG11 APOB HUWE1 USP8 LMAN2L NF1 PPA2 UGGT2 NUP188 ATL2 MOB4 GNPAT	1.70e-05	1061	135	15	33845483
Pubmed	Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair.	ADCY10 USP34 MAP1B ICE2 SPG11 HUWE1 TRRAP PARP1 RUVBL1 SMC3 PRIM1 PPA2 STEEP1 NUP188 ATP1A1 USP15 HDAC2	1.73e-05	1335	135	17	29229926
Pubmed	The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.	USP34 SRRM1 TRRAP CYFIP1 SMC3 STEEP1 MOB4	2.03e-05	212	135	7	33853758
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	RIPK1 MAP1B ICE2 MYO1B PARP1 CYFIP1 RUVBL1 SMC3 CCDC47 CRYBG3 ATP1A1 EIF4G3	2.18e-05	708	135	12	39231216
Pubmed	Direct interaction between the PRDM3 and PRDM16 tumor suppressors and the NuRD chromatin remodeling complex.	MAP1B MYO1B PARP1 CYFIP1 GNL2 ATP1A1 HDAC2	2.22e-05	215	135	7	30462309
Pubmed	A trimeric Rab7 GEF controls NPC1-dependent lysosomal cholesterol export.	TES MYO1B HUWE1 GDE1 LMAN2L CCDC47 PLD1 ATP1A1 HDAC2	2.40e-05	392	135	9	33144569
Pubmed	Discovery and Characterization of ZUFSP/ZUP1, a Distinct Deubiquitinase Class Important for Genome Stability.	USP34 UACA USP25 USP8 NF1 USP15	2.47e-05	147	135	6	29576527
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	EXPH5 SPG11 NEB TRRAP RYR3 CYFIP1 SMC3 XIRP2 GNL2 ATP1A1	2.60e-05	497	135	10	36774506
Pubmed	GRWD1 regulates ribosomal protein L23 levels via the ubiquitin-proteasome system.	MYO1B HUWE1 RUVBL1 ALDH1L2 ATP1A1 ATP1A3 EIF4G3	2.64e-05	221	135	7	29991511
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	SRRM1 NSD1 TRRAP LIN9 PARP1 PBRM1 SMC3 PHF3 STEEP1 GNL2 HDAC2	2.70e-05	608	135	11	36089195
Pubmed	Mapping the MOB proteins' proximity network reveals a unique interaction between human MOB3C and the RNase P complex.	MYO1B HUWE1 PARP1 CYFIP1 RUVBL1 SMC3 USP15 MOB4 HDAC2	2.76e-05	399	135	9	37536630
Pubmed	Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.	SRRM1 ZC3H14 MYO1B TRRAP CYFIP1 PBRM1 RUVBL1 SMC3 PHF3 GNL2 UTP20 PLD1 DCTN4	2.76e-05	847	135	13	35850772
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	SRRM1 ZC3H14 UACA MYO1B HUWE1 BRAP CCNT2 PARP1 CYFIP1 RUVBL1 SMC3 PHF3 ATP1A1 ATP1A3 USP15 HDAC2	2.85e-05	1247	135	16	27684187
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	TES SH3GL2 CNTLN DNAH7 RUVBL1 NANS KIAA1217 PRIM1 SLC25A15 ATP1A1 DCTN4 PIBF1 USP15	2.97e-05	853	135	13	28718761
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	SHANK1 MAP1B SH3GL2 HUWE1 SERPINB6 NF1 STXBP1 RUVBL1 KCNB1 KIAA1217 PPA2 CRYBG3 EIF4G3 USP15 HDAC2	3.84e-05	1139	135	15	36417873
Pubmed	Defining the human deubiquitinating enzyme interaction landscape.	MAP1B USP25 HUWE1 TRRAP USP8 PARP1 SMC3 PRIM1 GNL2 UGGT2 NUP188 EIF4G3 USP15 MOB4	3.87e-05	1005	135	14	19615732
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	USP34 SRRM1 ZC3H14 TRRAP CCNT2 PARP1 PBRM1 SMC3 NANS PHF3 PRIM1 STEEP1 MAGEC2 HDAC2	4.26e-05	1014	135	14	32416067
Pubmed	Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.	RIPK1 EXPH5 AOAH LAMA4 NEB DNAH7 EVI5 POSTN SERPINB6 NF1 UGT8 PLCL1 POLQ MAGEC2 HDAC2 TMEM234	4.40e-05	1293	135	16	15342556
Pubmed	Three differentially expressed Na,K-ATPase alpha subunit isoforms: structural and functional implications.	ATP1A1 ATP1A3	4.48e-05	3	135	2	2822726
Pubmed	C-->U editing of neurofibromatosis 1 mRNA occurs in tumors that express both the type II transcript and apobec-1, the catalytic subunit of the apolipoprotein B mRNA-editing enzyme.	APOB NF1	4.48e-05	3	135	2	11727199
Pubmed	Molecular linkage of the Ly-3 and Ly-2 genes. Requirement of Ly-2 for Ly-3 surface expression.	CD8B CD8B2	4.48e-05	3	135	2	3258885
Pubmed	Ly-36: a new mouse lymphocyte alloantigen defined by a Mus musculus molossinus-specific monoclonal antibody and controlled by a gene linked to Ly-2/3 region on chromosome 6.	CD8B CD8B2	4.48e-05	3	135	2	3378837
Pubmed	Evidence for close linkage of a mouse light chain marker with the Ly-2,3 locus.	CD8B CD8B2	4.48e-05	3	135	2	100557
Pubmed	Aquaporin-9 and urea transporter-A gene deletions affect urea transmembrane passage in murine hepatocytes.	POSTN SLC14A1	4.48e-05	3	135	2	23042941
Pubmed	Interaction of the nuclear matrix-associated region (MAR)-binding proteins, SATB1 and CDP/Cux, with a MAR element (L2a) in an upstream regulatory region of the mouse CD8a gene.	CD8B CD8B2	4.48e-05	3	135	2	9218488
Pubmed	Identification of a VxP Targeting Signal in the Flagellar Na+ /K+ -ATPase.	ATP1A1 ATP1A3	4.48e-05	3	135	2	26373354
Pubmed	Phosphatase and tensin homolog (PTEN) regulates hepatic lipogenesis, microsomal triglyceride transfer protein, and the secretion of apolipoprotein B-containing lipoproteins.	APOB MTTP	4.48e-05	3	135	2	19026012
Pubmed	Differential expression of Na+/K+-ATPase alpha-subunits in mouse hippocampal interneurones and pyramidal cells.	ATP1A1 ATP1A3	4.48e-05	3	135	2	17947306
Pubmed	Unraveling a revealing paradox: Why major histocompatibility complex I-signaled thymocytes "paradoxically" appear as CD4+8lo transitional cells during positive selection of CD8+ T cells.	CD8B CD8B2	4.48e-05	3	135	2	12810689
Interaction	EPHA1 interactions	USP34 GBF1 MYO1B HUWE1 NF1 SMC3 NANS GNL2 EIF4G3 ALK	3.46e-06	235	132	10	int:EPHA1
Interaction	SIRT7 interactions	USP34 SRRM1 ZC3H14 MAP1B NSD1 MYO1B HUWE1 TRRAP PBRM1 NF1 PHF3 GNL2 UTP20 NUP188 ATP1A1 EIF4G3 HDAC2	7.46e-06	744	132	17	int:SIRT7
Interaction	MYH9 interactions	GBF1 UACA MAP1B USP25 MYO1B APOB HUWE1 TRRAP CYFIP1 RUVBL1 PHF3 SPATA16 ATP1A1 USP15 CCDC180 ALK HDAC2	8.87e-06	754	132	17	int:MYH9
Interaction	C5AR2 interactions	EXOC6 GBF1 PLD1 ATP1A3 ATL2 TMEM234	1.23e-05	78	132	6	int:C5AR2
Interaction	MECOM interactions	MAP1B MYO1B NEB PARP1 CYFIP1 RUVBL1 SMC3 GNL2 ATP1A1 CCDC180 HDAC2	2.43e-05	358	132	11	int:MECOM
Interaction	AR interactions	USP34 EXPH5 NSD1 MYO1B HUWE1 DCC RAB11FIP1 TRRAP LIN9 PARP1 CYFIP1 PBRM1 RUVBL1 SMC3 PHF3 KIAA1217 NUP188 VAV2 HDAC2	2.52e-05	992	132	19	int:AR
Interaction	TNFRSF8 interactions	DPY19L1 TRRAP NAA25 ALK	4.82e-05	31	132	4	int:TNFRSF8
Interaction	KCNA3 interactions	ADCY10 SRRM1 RIPK1 MAP1B EXPH5 ICE2 MYO1B PARP1 CYFIP1 RUVBL1 SMC3 CCDC47 PHF3 CRYBG3 ATP1A1 EIF4G3 POLQ	5.54e-05	871	132	17	int:KCNA3
Interaction	MYOF interactions	TES GBF1 APOB PARP1 SMC3 ATP1A1	5.67e-05	102	132	6	int:MYOF
Interaction	USP15 interactions	GBF1 RIPK1 HUWE1 BRAP USP8 PARP1 RUVBL1 KCNB1 SMC3 DCTN4 PIBF1 USP15 HDAC2	6.25e-05	546	132	13	int:USP15
Interaction	MILR1 interactions	GBF1 BTNL8 NAA25 PRIM1 UQCC1	7.25e-05	66	132	5	int:MILR1
Interaction	USP8 interactions	SHANK1 HUNK TRRAP TSEN2 USP8 SCNN1G USP15	7.64e-05	156	132	7	int:USP8
GeneFamily	ATP binding cassette subfamily A	ABCA10 ABCA9 ABCA5	3.16e-05	14	82	3	805
GeneFamily	Ubiquitin specific peptidases	USP34 USP25 USP8 USP15	1.21e-04	56	82	4	366
GeneFamily	ATPase Na+/K+ transporting subunits	ATP1A1 ATP1A3	4.20e-04	7	82	2	1208
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	USP34 ZC3H14 GBF1 MAP1B MYO1B SPG11 TRRAP EVI5 ZFYVE9 SMC3 PHF3 UTP20 CRYBG3 EIF4G3 PIBF1 USP15 MOB4	1.66e-06	856	133	17	M4500
ToppCell	NS-critical-d_07-13-Epithelial-Ionocyte\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	STAB2 DPY19L2 LAMA4 POSTN ST8SIA6 SLC14A1 SCNN1G DGKI PLCL1 ALK	2.46e-10	183	135	10	ba43bca2b45be1008eebd3f033cecb061fb3a966
ToppCell	Ionocyte\|World / shred by cell class for nasal brushing	FAT4 DPY19L2 LAMA4 POSTN SLC14A1 DGKI PLCL1 ALK	2.41e-08	154	135	8	6b78fb0c96fc7b5e901c39b3424f4aa8d0a6b9cf
ToppCell	critical-Epithelial-Ionocyte\|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	STAB2 DPY19L2 LAMA4 POSTN SLC14A1 SCNN1G DGKI ALK	9.56e-08	184	135	8	58d36577eff814d46d72f031f3533d71549e3d6e
ToppCell	moderate-Epithelial-Ionocyte\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	STAB2 DPY19L2 LAMA4 POSTN SLC14A1 SCNN1G DGKI PLCL1	1.17e-07	189	135	8	6011b747e27d61d222380a7bffdd921a68e9b657
ToppCell	critical-Epithelial-Ionocyte\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	DPY19L2 POSTN ST8SIA6 SLC14A1 SCNN1G DGKI PLCL1 ALK	1.22e-07	190	135	8	05a2c3549b68f49081723bf35db14974274419d5
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	EXPH5 MYO1B PLEKHD1 ABCA10 ABCA9 ABCA5 PLCL1 ATP1A1	1.49e-07	195	135	8	a38d9dc6192aea673d96fda6b25e81223fda3abf
ToppCell	Tracheal-10x5prime-Epithelial-Epi_airway_neuro-secretory-Ionocyte_n_Brush\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	STAB2 DPY19L2 SH3GL2 POSTN SLC14A1 SCNN1G DGKI ALK	1.55e-07	196	135	8	50aaca81b593ff71790bb75403b2e4c3ab03a6d2
ToppCell	NS-control-d_0-4-Epithelial-Ionocyte\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	STAB2 DPY19L2 POSTN SCNN1G DGKI PLCL1 VAV2	7.63e-07	166	135	7	6d9fb239f69ba519844f593c00d515e1aac4ff50
ToppCell	NS-critical-d_16-33-Epithelial-Ionocyte\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	STAB2 POSTN ST8SIA6 SLC14A1 DGKI PLCL1 ALK	8.27e-07	168	135	7	6a233045638cb83dab64789b996b7598c325001e
ToppCell	NS-moderate-d_16-33-Epithelial-Ionocyte\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	STAB2 DPY19L2 LAMA4 POSTN SLC14A1 SCNN1G DGKI	1.31e-06	180	135	7	8af8b4af2dc72223ac71fc027e0d4280c5dd81f8
ToppCell	5'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte-Ionocyte_L.0.7.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DPY19L2 POSTN SLC14A1 SCNN1G DGKI ATP1A1 ALK	1.36e-06	181	135	7	40df0afcb6848202da54670e84f22d7c3a515d01
ToppCell	5'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DPY19L2 POSTN SLC14A1 SCNN1G DGKI ATP1A1 ALK	1.36e-06	181	135	7	2b53a65ca5616a7b9f64232c3e0b7212d1e2f063
ToppCell	5'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic-ionocyte\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DPY19L2 POSTN SLC14A1 SCNN1G DGKI ATP1A1 ALK	1.36e-06	181	135	7	6aef84616e8d2faf54b7e9e6cd02f33c3066dabc
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DPY19L2 MYO1B PLEKHD1 ABCA10 ABCA9 MAGEB10 ABCA5	1.36e-06	181	135	7	e0abf2707d9e0aa942c657eef7d2cbcd02f060dd
ToppCell	5'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DPY19L2 POSTN SLC14A1 SCNN1G DGKI ATP1A1 ALK	1.36e-06	181	135	7	40d3829ae4aaf81e8616c3499ff8933137fc1cc4
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DPY19L2 EXPH5 MYO1B PLEKHD1 ABCA10 ABCA5 ATP1A1	1.47e-06	183	135	7	2f0ee40e69ad1259e56e8ee4b352736900eb8901
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT4 STAB2 APOB DCC NEB RYR3 XIRP2	1.52e-06	184	135	7	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT4 STAB2 APOB DCC NEB RYR3 XIRP2	1.52e-06	184	135	7	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT4 STAB2 APOB DCC NEB RYR3 XIRP2	1.52e-06	184	135	7	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	moderate-Epithelial-Ionocyte\|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	STAB2 DPY19L2 LAMA4 POSTN SLC14A1 SCNN1G DGKI	1.69e-06	187	135	7	3e3fe2d5712a0ac477cddefe56705d4b8d8f7eac
ToppCell	Children_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FAT4 UACA BTNL8 POSTN SERPINB10 ST8SIA6 KIAA1217	2.16e-06	194	135	7	68004855b23fe1e31e8452d70effabc78a4a0bd3
ToppCell	Tracheal-10x5prime-Epithelial-Epi_airway_neuro-secretory\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	STAB2 DPY19L2 SH3GL2 SLC14A1 SCNN1G DGKI ALK	2.31e-06	196	135	7	a4cc02ea41479d24044bd2ca6441f85d683c0ca9
ToppCell	Somatosensory_Cortex_(S1)-Neuronal\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MAP1B SH3GL2 STXBP1 KCNB1 ABCA5 DGKI ATP1A3	2.47e-06	198	135	7	c01091ef18e096d792ea2a7a715764a5b215355f
ToppCell	primary_auditory_cortex_(A1C)-Neuronal\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MAP1B SH3GL2 STXBP1 KCNB1 ABCA5 DGKI ATP1A3	2.47e-06	198	135	7	6d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCell	Neuronal\|World / cells hierarchy compared to all cells using T-Statistic	MAP1B SH3GL2 STXBP1 KCNB1 ABCA5 DGKI ATP1A3	2.64e-06	200	135	7	48d801219bc771d6c7e151dc88ca4c179988de85
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DPY19L2 MYO1B PLEKHD1 ABCA10 MAGEB10 ABCA5	8.82e-06	158	135	6	7960337d87afecf2692ab65e5991f052ceddfacc
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DPY19L2 EXPH5 MYO1B PLEKHD1 ABCA5 ATP1A1	1.02e-05	162	135	6	36ddebe3bb172c992739353b7b049b2dde98b559
ToppCell	control-Epithelial-Ionocyte\|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	DPY19L2 POSTN SCNN1G DGKI PLCL1 VAV2	1.13e-05	165	135	6	5cfba9a46bd8ceeca74a6493057b4d38af6b06fe
ToppCell	control-Epithelial-Ionocyte\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	DPY19L2 POSTN SCNN1G DGKI PLCL1 VAV2	1.25e-05	168	135	6	327b02f19f4a8607c033203824fdc60a1254331f
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_ETV4\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DPY19L1 EXPH5 LRRC3B KIAA1217 CRYBG3 VAV2	1.29e-05	169	135	6	716e9d4c5fb99c56b76afaa5ed90bfa859fde802
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SHANK1 EXPH5 SH3GL2 PLEKHD1 STXBP1 ATP1A3	1.38e-05	171	135	6	99176a932569fa1c7e1c01009684f5a65244b96e
ToppCell	COVID-19-Heart-T_cell\|COVID-19 / Disease (COVID-19 only), tissue and cell type	DCC NEB RYR3 SPATA16 SEL1L2 ALK	1.38e-05	171	135	6	b2e753e811a7639956994609f73efcdb62d04f82
ToppCell	Nasal_Brush-Epithelial-Ionocytes\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	LAMA4 POSTN ST8SIA6 SLC14A1 SCNN1G DGKI	1.43e-05	172	135	6	04fabb40fa9357d8902f3b04adc15231626cd9f8
ToppCell	Nasal_Brush-Epithelial-Ionocytes\|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X	LAMA4 POSTN ST8SIA6 SLC14A1 SCNN1G DGKI	1.43e-05	172	135	6	dd3a23dc78dc6939f41126f8d7bd23a2e4713647
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FAT4 DPY19L1 LRRC3B KIAA1217 CRYBG3 VAV2	1.53e-05	174	135	6	7d4b860e05b5931f6f9d757a68f75ff35597a47a
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DPY19L2 ST8SIA6 ABCA5 UGT8 DGKI PLCL1	1.58e-05	175	135	6	77c16e615c0fb9c83f29d7e0a547be72635fac81
ToppCell	NS-moderate-d_0-4-Epithelial-Ionocyte\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	LAMA4 POSTN SLC14A1 SCNN1G DGKI PLCL1	1.58e-05	175	135	6	a1e0a15c69211d6db2edeb101476f0f6e08b90c8
ToppCell	3'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	STAB2 DPY19L2 LAMA4 SLC14A1 SCNN1G DGKI	1.68e-05	177	135	6	6d89042bda8e244babb68929e84b25edcb545a77
ToppCell	3'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte-Ionocyte_L.0.7.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	STAB2 DPY19L2 LAMA4 SLC14A1 SCNN1G DGKI	1.68e-05	177	135	6	daaccf1249dcf816df4caca695a944f53078291a
ToppCell	3'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic-ionocyte\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	STAB2 DPY19L2 LAMA4 SLC14A1 SCNN1G DGKI	1.68e-05	177	135	6	338bdda26796bf4e16072878c070212d1006cf57
ToppCell	NS-moderate-d_07-13-Epithelial-Ionocyte\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DPY19L2 POSTN SLC14A1 SCNN1G DGKI PLCL1	1.68e-05	177	135	6	99500aed584f793aaf308f8afbf5d1c6a9b4ee55
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DPY19L2 EXPH5 MYO1B PLEKHD1 CRYBG3 ATP1A1	1.68e-05	177	135	6	c9e8149639551a4c8daa90fcb2b895fdcff2e2ba
ToppCell	3'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	STAB2 DPY19L2 LAMA4 SLC14A1 SCNN1G DGKI	1.68e-05	177	135	6	c5a16f984c836dbf7d0faf061677844167ab612a
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DPY19L1 RYR3 LRRC3B KIAA1217 CRYBG3 VAV2	1.85e-05	180	135	6	e8841ef1239f9ee73ac4f4e11faca0742694f368
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DPY19L2 ABCA5 UGT8 DGKI PLCL1 CRYBG3	1.91e-05	181	135	6	30729f0364f719c044712a51453e22dc2c1a232b
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DPY19L2 ST8SIA6 ABCA5 UGT8 DGKI PLCL1	2.22e-05	186	135	6	a6ef5d5944af5689b5f27bef89cd05645eedbe50
ToppCell	Control-Fibroblasts-Other_FB\|Control / group, cell type (main and fine annotations)	FAT4 UACA LAMA4 ABCA10 ABCA9 CAB39L	2.29e-05	187	135	6	bd3739c4a52aa1ba5deffd778e113a9800f7e158
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	EXPH5 PLEKHD1 ABCA10 ABCA5 PLCL1 ATP1A1	2.43e-05	189	135	6	977a813e5d7a5a561c1fced2bbf21c20056b88d8
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Ascending_Thin_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	EXPH5 USP25 HUNK PLEKHD1 CCDC198 UGT8	2.51e-05	190	135	6	59bbbd2c8d4b7ce46c54ca8022b1557e7e5eee2a
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	EXPH5 PLEKHD1 ABCA10 ABCA5 PLCL1 ATP1A1	2.51e-05	190	135	6	e252e925600e6457fa6e362a55217f4cffa75cdb
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	UACA MAP1B LAMA4 ABCA9 POSTN SLC14A1	2.58e-05	191	135	6	107113b930d9ad171f1b2aa20df4567c94fae7d8
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	UACA MAP1B LAMA4 ABCA9 POSTN SLC14A1	2.58e-05	191	135	6	bc353a79a1d11ca52bba5e3874a80d432e1a7715
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	FAT4 UACA LAMA4 ABCA10 ABCA9 CAB39L	2.58e-05	191	135	6	6688cee34beee4f151ac17fccbc9c26a9aad72e1
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	UACA MAP1B LAMA4 ABCA10 ABCA9 KIAA1217	2.66e-05	192	135	6	bc84b9ce01b4d826a682842ab8a395dac9b91183
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	UACA MAP1B LAMA4 ABCA10 ABCA9 KIAA1217	2.66e-05	192	135	6	0ab1176cfbb0de8dd1f22c6e2c41265cf6c10ee1
ToppCell	COVID-19-Fibroblasts-Other_FB\|COVID-19 / group, cell type (main and fine annotations)	FAT4 UACA MAP1B ABCA9 POSTN DGKI	2.74e-05	193	135	6	e6b75be08e33c1de079fb5c02f0b4468128b369c
ToppCell	PCW_07-8.5-Epithelial-Epithelial_alveolar-distal-epi_CTGF^high_distal_(3)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	TES EXPH5 SH3GL2 RAB11FIP1 CCDC198 CD8B2	2.74e-05	193	135	6	ab78fb1603ea6f720ba2d30148fe65dccf271fe1
ToppCell	Children_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FAT4 UACA BTNL8 POSTN ST8SIA6 KIAA1217	2.82e-05	194	135	6	71ac69cdf7a08ca3ddfb5b492b14ac56b6cd5e5d
ToppCell	5'-GW_trimst-2-LargeIntestine-Epithelial-mature_enterocytic-Enterocyte\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	BTNL8 APOB CCDC198 MTTP UGT8 ATP1A1	2.82e-05	194	135	6	fcbf9c4f3801ab1a34fcd62c752fabc97fc7bde1
ToppCell	PCW_13-14-Epithelial-Epithelial_alveolar-distal-epi_SFTPC^high_distal_(9)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	TES EXPH5 SH3GL2 RAB11FIP1 CCDC198 UGT8	2.82e-05	194	135	6	c47fc3f716ab091a39c20d7639ac783029589ee5
ToppCell	10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-SMC_COL-D\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	UACA MYO1B POSTN ALDH1L2 KIAA1217 CYB5R2	2.90e-05	195	135	6	78cfde21dde4b877fc76c8b0d5ddaabe44b912d7
ToppCell	PCW_13-14-Epithelial-Epithelial_alveolar-distal-epi_CTGF^high_distal_(3)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	TES EXPH5 SH3GL2 RAB11FIP1 CCDC198 UGT8	2.90e-05	195	135	6	62d369a8af2b76a2553bc8ff9cb89a133b060123
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAP1B NSD1 HUWE1 STXBP1 KCNB1 TSHZ1	2.90e-05	195	135	6	3e519cffa6144a62b06124642a14c9ff39b76554
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MAP1B SH3GL2 STXBP1 KCNB1 ABCA5 DGKI	2.98e-05	196	135	6	676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DPY19L2 EXPH5 MYO1B PLEKHD1 ABCA5 ATP1A1	2.98e-05	196	135	6	f40d10ea7714067585493fdc89744714aa427de8
ToppCell	COVID-19_Severe-PLT_4\|World / Disease Group and Platelet Clusters	SRRM1 SMC3 XIRP2 PHF3 USP15 MOB4	2.98e-05	196	135	6	ad43efdd4d73b6615f65f06a315b33576e317473
ToppCell	nucseq-Endothelial-Endothelial_Vascular\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	EXOC6 UACA BTNL8 POSTN ST8SIA6 KIAA1217	2.98e-05	196	135	6	686533fd3fba8e4df96b9dd1307e870e89db4332
ToppCell	10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-Pericyte-C\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	UACA LAMA4 MYO1B ABCA10 ABCA9 ST8SIA6	2.98e-05	196	135	6	12d9028f90c057c6e5cff00301793fa550e86c5a
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Degenerative_Distal_Convoluted_Tubule_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DPY19L2 EXPH5 MYO1B PLEKHD1 ABCA5 ATP1A1	2.98e-05	196	135	6	b8350340d86e4524e9616a427e7f2e116a6fb3be
ToppCell	PCW_10-12-Epithelial-Epithelial_alveolar-distal-epi_SFTPC^high_distal_(9)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	TES EXPH5 SH3GL2 RAB11FIP1 CCDC198 UGT8	3.07e-05	197	135	6	22b26bac3a99b20c73bfa6e6f81026d064eaa9e8
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_alveolar-AT1\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	TES SH3GL2 MYO1B RAB11FIP1 SCNN1G PLCL1	3.07e-05	197	135	6	8d5097898dd01cedb04cb694cb480c931e08462c
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DPY19L2 DNAH7 CFAP65 KCNB1 CCDC180 NEK11	3.07e-05	197	135	6	74a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCell	Bronchus_Control_(B.)-Epithelial-TX-AT1\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	STAB2 DPY19L2 POSTN SLC14A1 SCNN1G DGKI	3.07e-05	197	135	6	f7ef62d78336812573148f8bfce401877ec4e29c
ToppCell	10x3'2.3-week_17-19-Endothelial\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	STAB2 UACA MAP1B LAMA4 MYO1B KIAA1217	3.16e-05	198	135	6	2630a7a6e56febe5c0b0bde70dd7292fa1650c47
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MAP1B SH3GL2 STXBP1 ABCA5 DGKI ATP1A3	3.16e-05	198	135	6	4ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW23-Neuronal-Neurons\|GW23 / Sample Type, Dataset, Time_group, and Cell type.	DPY19L1 HUNK CENPBD1P LRRC3B SCNN1G HDAC2	3.16e-05	198	135	6	90ebefc9ba8dc2a81471e5693384f5ce56f06298
ToppCell	10x3'2.3-week_17-19-Endothelial-stroma\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	STAB2 UACA MAP1B LAMA4 MYO1B KIAA1217	3.16e-05	198	135	6	1e83bec16dcd60460422625f89952ff506d6be51
ToppCell	Tracheal-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Duct\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	EXPH5 RAB11FIP1 KIAA1217 ATP1A1 ATL2 PPTC7	3.25e-05	199	135	6	527aae1d9d37a50deefc01fc0c064a53673681bd
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	USP34 FAT4 UACA LAMA4 STXBP1 KIAA1217	3.34e-05	200	135	6	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FAT4 MAP1B LAMA4 ABCA10 ABCA9 PLCL1	3.34e-05	200	135	6	58b38f9a484ee94191091a0659ed62ebed2d4a14
ToppCell	3'_v3-Lung-Lymphocytic_T_CD8-Trm_gut_CD8\|Lung / Manually curated celltypes from each tissue	DPY19L2 PARP8 LAMA4 APOB CD8B	7.04e-05	141	135	5	7cbe8abdd004430d58ce31e0b613894a4cf6726e
ToppCell	Adult-Immune-mast_cell-D231\|Adult / Lineage, Cell type, age group and donor	PLEKHD1 CD8B ST8SIA6 SLC14A1 PRELID2	1.17e-04	157	135	5	4c63bb91f8708644e6ce2500072a4eeb8e1079dd
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Connecting_Tubule_Intercalated_Cell_Type_A\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DPY19L2 MYO1B ST8SIA6 ABCA5 SCNN1G	1.28e-04	160	135	5	86fde32f096eaf9ea3677f57169cdcc0a57bb8dd
ToppCell	COVID-19-kidney-Technical/muscle_(Imm)\|kidney / Disease (COVID-19 only), tissue and cell type	DCC KCNB1 SPATA16 SEL1L2 ALK	1.39e-04	163	135	5	19c28ce16a588a7f4a035c32726f6ccd67702b5b
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L4\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	EXPH5 LAMA4 XIRP2 TSHZ1 ATP1A1	1.39e-04	163	135	5	1e8ab00ecc2d2ba35aa6745c0ed38663e26312e8
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L4-L4_IT_VISp_Rspo1\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	EXPH5 LAMA4 XIRP2 TSHZ1 ATP1A1	1.39e-04	163	135	5	431221a41d396b09170476179590eaf8a55266d8
ToppCell	facs-Lung-24m-Hematologic-lymphocytic-mature_NK_T_cell-mature_NK_T_cell_l22\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TDRD9 CNTLN LIN9 RYR3 STXBP1	1.52e-04	166	135	5	bcdaab49bde5beba750b76fdcc3781a3c12c4fff
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	EXOC6 MAP1B ST8SIA6 SLC14A1 CRYBG3	1.52e-04	166	135	5	8e5f2afbeffae5e77fcb29e8fe9f5aa49779b619
ToppCell	facs-Lung-24m-Hematologic-lymphocytic-mature_NK_T_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TDRD9 CNTLN LIN9 RYR3 STXBP1	1.52e-04	166	135	5	5e3b998d740b24f790fad37350d704ca0ea10b77
ToppCell	lung-Ciliated_Epithelia\|lung / shred on tissue and cell subclass	PIH1D2 DNAH7 RUVBL1 CCDC180 NEK11	1.56e-04	167	135	5	26cf1cfa58ee74794449a87eb19cd896e1ec8892
ToppCell	PND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	STAB2 TDRD9 PARP1 PRELID2 PRIM1	1.56e-04	167	135	5	53e32d6687a07f486141df9f4ab998af4c03a507
ToppCell	E18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_prolif\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	HUNK POSTN NAA25 ABCA5 PRIM1	1.56e-04	167	135	5	b0eb7a40491dd2432f5282f578ce569df86d21a7
ToppCell	E18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_prolif\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DPY19L1 NEB RYR3 PRIM1 CYB5R2	1.65e-04	169	135	5	16c52a0f6d96ecc1832922fce9b39691849f0d73
ToppCell	BL-critical-LOC-Epithelial-Ionocyte\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	FAT4 POSTN SLC14A1 SCNN1G DGKI	1.69e-04	170	135	5	b465df2dac6b4e98b4ede6ad0c6347656757885c
ToppCell	TCGA-Endometrium-Solid_Tissue_Normal-Endometrium_normal_tissue-Endometrium\|TCGA-Endometrium / Sample_Type by Project: Shred V9	ABCA9 RYR3 KCNB1 PLCL1 SEL1L2	1.69e-04	170	135	5	cdc19013da7c41d1ed8400a6a643e4c684ff9912
ToppCell	TCGA-Endometrium-Solid_Tissue_Normal\|TCGA-Endometrium / Sample_Type by Project: Shred V9	ABCA9 RYR3 KCNB1 PLCL1 SEL1L2	1.69e-04	170	135	5	0bde0a40440c7fdf7ba89cac8831d4014e7a4807
ToppCell	TCGA-Endometrium-Solid_Tissue_Normal-Endometrium_normal_tissue\|TCGA-Endometrium / Sample_Type by Project: Shred V9	ABCA9 RYR3 KCNB1 PLCL1 SEL1L2	1.69e-04	170	135	5	516b38c4ecf6b0b04c5d4f80c510dcc00b328c6f
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	EXPH5 ABCA10 ABCA9 ABCA5 ATP1A1	1.84e-04	173	135	5	0c74bdb40e635d906fd180412c23bf7fed61621e
ToppCell	CV-Mild-7\|Mild / Virus stimulation, Condition and Cluster	DPY19L1 ICE2 MYO1B CAB39L DCTN4	1.84e-04	173	135	5	c9bbca9313a0fdf146c8c995624b94b937e818d8
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DPY19L1 RYR3 LRRC3B KIAA1217 CRYBG3	1.84e-04	173	135	5	95c723b09254ae7131fe5ba0841472502e83269b
Disease	Colorectal Carcinoma	SHANK1 MAP1B PARP8 MYO1B APOB DCC ABCA10 ABCA9 POSTN PARP1 NF1 ABCA5 LRRC3B SCNN1G	3.38e-06	702	132	14	C0009402
Disease	Intellectual Disability	ZC3H14 MAP1B NSD1 DCC TRRAP TSEN2 PARP1 LMAN2L NF1 CCDC47 ATP1A1	5.71e-06	447	132	11	C3714756
Disease	osteoarthritis, hip, osteoarthritis, knee	BTNL8 USP8 NF1 DGKI UQCC1	8.76e-06	62	132	5	EFO_0004616, EFO_1000786
Disease	melanoma	FAT4 MYO1B DCC TRRAP PARP1 NF1 ALK HDAC2	1.67e-05	248	132	8	C0025202
Disease	epilepsy	GBF1 C6orf89 BRAP NAA25	3.41e-05	41	132	4	EFO_0000474
Disease	neuroligin-1 measurement	STAB2 SPATA16	5.94e-05	3	132	2	EFO_0802802
Disease	periostin measurement	STAB2 POSTN	1.18e-04	4	132	2	EFO_0020628
Disease	Flushing	C6orf89 BRAP	1.18e-04	4	132	2	HP_0031284
Disease	Schizophrenia	SHANK1 DCC TRRAP BRAP CFAP65 CYFIP1 PBRM1 LMAN2L STXBP1 KCNB1 ALK HDAC2 GNPAT	1.72e-04	883	132	13	C0036341
Disease	factor VIII measurement, coagulation factor measurement	STAB2 VAV2	1.97e-04	5	132	2	EFO_0004630, EFO_0004634
Disease	alcohol use disorder (implicated_via_orthology)	RYR3 PBRM1 STXBP1 ATP1A1 ATP1A3 HDAC2	2.53e-04	195	132	6	DOID:1574 (implicated_via_orthology)
Disease	Colorectal Neoplasms	DCC ABCA10 ABCA9 POSTN PARP1 ABCA5 LRRC3B	2.59e-04	277	132	7	C0009404
Disease	obsessive-compulsive disorder, attention deficit hyperactivity disorder, Tourette syndrome, unipolar depression, bipolar disorder, autism spectrum disorder, schizophrenia, anorexia nervosa	DCC LMAN2L KCNB1 DGKI PLCL1 MOB4	2.90e-04	200	132	6	EFO_0003756, EFO_0003761, EFO_0003888, EFO_0004242, EFO_0004895, MONDO_0004985, MONDO_0005090, MONDO_0005351
Disease	coffee consumption	C6orf89 BRAP NAA25	3.95e-04	32	132	3	EFO_0004330
Disease	familial hemiplegic migraine (implicated_via_orthology)	ATP1A1 ATP1A3	4.11e-04	7	132	2	DOID:0060178 (implicated_via_orthology)
Disease	fornix volume measurement	EVI5 PLCL1	4.11e-04	7	132	2	EFO_0803381
Disease	Profound Mental Retardation	NSD1 DCC TSEN2 PARP1 NF1	4.13e-04	139	132	5	C0020796
Disease	Mental Retardation, Psychosocial	NSD1 DCC TSEN2 PARP1 NF1	4.13e-04	139	132	5	C0025363
Disease	Mental deficiency	NSD1 DCC TSEN2 PARP1 NF1	4.13e-04	139	132	5	C0917816
Disease	alcohol use disorder measurement	C6orf89 CNTLN BRAP NF1 MTTP CAB39L	4.16e-04	214	132	6	EFO_0009458
Disease	carbohydrate intake measurement	C6orf89 BRAP NAA25	4.73e-04	34	132	3	EFO_0010811
Disease	osteoarthritis, spine, body mass index	PER3 SPATA16	5.46e-04	8	132	2	EFO_0004340, EFO_1000787
Disease	epilepsy (is_implicated_in)	KCNB1 ATP1A3	7.00e-04	9	132	2	DOID:1826 (is_implicated_in)
Disease	Pulmonary Cystic Fibrosis	SCNN1G DCTN4	7.00e-04	9	132	2	C0392164
Disease	Fibrocystic Disease of Pancreas	SCNN1G DCTN4	7.00e-04	9	132	2	C1527396
Disease	visual epilepsy (biomarker_via_orthology)	MAP1B SH3GL2 PLD1 HDAC2	7.26e-04	90	132	4	DOID:11832 (biomarker_via_orthology)
Disease	Inherited neuropathies	APTX SPG11 MTTP	7.66e-04	40	132	3	C0598589
Disease	Cutaneous Melanoma	TRRAP NF1 ALK	8.24e-04	41	132	3	C0151779
Disease	Tetralogy of Fallot	C6orf89 BRAP	8.73e-04	10	132	2	HP_0001636
Disease	platelet glycoprotein ib alpha chain measurement	C6orf89 BRAP	8.73e-04	10	132	2	EFO_0020645
Disease	familial hypercholesterolemia (is_implicated_in)	APOB MTTP	8.73e-04	10	132	2	DOID:13810 (is_implicated_in)
Disease	Adenocarcinoma of large intestine	RIPK1 DCC TRRAP NEK11	9.25e-04	96	132	4	C1319315
Disease	forced expiratory volume, body mass index	C6orf89 BRAP	1.06e-03	11	132	2	EFO_0004314, EFO_0004340
Disease	Cystic Fibrosis	SCNN1G DCTN4	1.06e-03	11	132	2	C0010674
Disease	psychological resilience measurement	SH3GL2 CNTLN	1.27e-03	12	132	2	EFO_0009945
Disease	nervous system disease (implicated_via_orthology)	ATP1A1 ATP1A3	1.27e-03	12	132	2	DOID:863 (implicated_via_orthology)
Disease	blood copper measurement	C6orf89 BRAP NAA25	1.47e-03	50	132	3	EFO_0007578
Disease	idiopathic osteonecrosis of the femoral head	RIPK1 SH3GL2 TSEN2	1.65e-03	52	132	3	EFO_1001930
Disease	insulin metabolic clearance rate measurement, glucose homeostasis measurement	DCC ST8SIA6	1.74e-03	14	132	2	EFO_0006830, EFO_0006896
Disease	BMI-adjusted adiponectin measurement	PBRM1 ALK	2.01e-03	15	132	2	EFO_0007737
Disease	tumor necrosis factor measurement	C6orf89 BRAP	2.01e-03	15	132	2	EFO_0010834
Disease	pro-hydroxy-pro measurement	SERPINB10 ALK	2.29e-03	16	132	2	EFO_0021132
Disease	Rolandic epilepsy	DPY19L2 ALDH1L2	2.29e-03	16	132	2	Orphanet_1945
Disease	Sarcomatoid Renal Cell Carcinoma	SHANK1 PBRM1 LMAN2L ALK	2.66e-03	128	132	4	C1266043
Disease	Chromophobe Renal Cell Carcinoma	SHANK1 PBRM1 LMAN2L ALK	2.66e-03	128	132	4	C1266042
Disease	Collecting Duct Carcinoma of the Kidney	SHANK1 PBRM1 LMAN2L ALK	2.66e-03	128	132	4	C1266044
Disease	Papillary Renal Cell Carcinoma	SHANK1 PBRM1 LMAN2L ALK	2.66e-03	128	132	4	C1306837
Disease	Renal Cell Carcinoma	SHANK1 PBRM1 LMAN2L ALK	2.66e-03	128	132	4	C0007134
Disease	Child Behaviour Checklist assessment	RIPK1 SPATA16	2.90e-03	18	132	2	EFO_0005661
Disease	syndrome (implicated_via_orthology)	NSD1 ZDHHC15	2.90e-03	18	132	2	DOID:225 (implicated_via_orthology)
Disease	Myeloid Leukemia	SMC3 HDAC2	2.90e-03	18	132	2	C0023470
Disease	Leukemia, Monocytic, Chronic	SMC3 HDAC2	2.90e-03	18	132	2	C0023466
Disease	hip bone size	KIAA1217 PLCL1 NEK11	3.12e-03	65	132	3	EFO_0004844
Disease	temporal lobe epilepsy (is_marker_for)	CYFIP1 HDAC2	3.58e-03	20	132	2	DOID:3328 (is_marker_for)
Disease	BMI-adjusted waist-hip ratio, physical activity measurement	TSEN2 PBRM1 UQCC1	3.70e-03	69	132	3	EFO_0007788, EFO_0008002
Disease	Nonorganic psychosis	SHANK1 PBRM1 HDAC2	3.70e-03	69	132	3	C0349204
Disease	platelet crit	SRRM1 C6orf89 EXPH5 APOB BRAP PARP1 NAA25 SERPINB6 NF1 PRIM1 USP15	3.73e-03	952	132	11	EFO_0007985
Disease	stroke, coronary artery disease	C6orf89 BRAP	3.94e-03	21	132	2	EFO_0000712, EFO_0001645
Disease	Obsessive-compulsive trait	SH3GL2 NEK11	3.94e-03	21	132	2	HP_0008770
Disease	hip bone mineral density, fat body mass	TDRD9 NEK11	4.33e-03	22	132	2	EFO_0005409, EFO_0007702
Disease	Conventional (Clear Cell) Renal Cell Carcinoma	SHANK1 PBRM1 LMAN2L ALK	4.47e-03	148	132	4	C0279702

Protein segments in the cluster

Peptide	Gene	Start	Entry
LILISMMHPNKKYEE	ABCA5	46	Q8WWZ7
TKYISKPENLKLMMN	CAB39L	246	Q9H9S4
MKIIRDSTPNQYMVL	BRAP	191	Q7Z569
PIKMKIPIANTEKYM	CCNT2	481	O60583
PSRSMDLEMKQLQYK	CNTLN	1086	Q9NXG0
LKVEMPMNLKVIIYE	CRYBG3	2471	Q68DQ2
LEMKYGNEIMNKDPV	ABCA10	1136	Q8WWZ4
MQMPQYQGRTKLVKD	BTNL8	76	Q6UX41
YLLEMKLKNLAQMEP	ABCA9	1516	Q8IUA7
SKEVNEIMVKMPYQC	ALDH1L2	431	Q3SY69
MVYTSRMPKLSQVNE	FAT4	4861	Q6V0I7
KISMQDPKMQVYKDE	APTX	186	Q7Z2E3
LEMSLQKYVMESILK	ADCY10	261	Q96PN6
LTKEVMEYPAIMLKE	CCDC180	606	Q9P1Z9
DYIKMSINPKKLVMG	CTBS	236	Q01459
KMTQYLENMKIGETI	CYB5R2	101	Q6BCY4
IEPDYKFSTLLMMLK	NSD1	901	Q96L73
MVEYEIDLQKMPLGK	PARP1	686	P09874
MTTPEKLYSNVMQTL	AOAH	386	P28039
LQYVKTLMEVMPKIC	CYFIP1	946	Q7L576
CKPMQMYVLDIKDTK	FBXO42	641	Q6P3S6
KPNTMYEFSVMVTKN	DCC	911	P43146
KSKYMTPMQQKLNEV	PBRM1	651	Q86U86
REMTQAPYLEIKKQM	PARP8	616	Q8N3A8
PYKVVMKQSKLPMSL	GNL2	106	Q13823
MNTEAEKLKSYSMPI	LIN9	366	Q5TKA1
EMYVLNPVKSSKEMQ	MAP1B	421	P46821
YQMKEPITKADMLRN	MAGEB10	126	Q96LZ2
PVTEAEMLMIVIKYK	MAGEC2	161	Q9UBF1
TKFMDQKNSLYLMPI	CFAP65	1716	Q6ZU64
KIMESFKNMVPQQAL	ATP1A1	156	P05023
PLMNMVIYSIDKAKK	CCDC47	381	Q96A33
IMVVQEMKKYFPSER	PER3	56	P56645
DKMVSVLYNVITPML	OR4Q2	266	P0C623
ELPQEMNKYMLAIVQ	MTTP	566	P55157
SMPIKDQYSELLKMT	EVI5	181	O60447
MIMNDKLTEYPLVIN	DPY19L1	86	Q2PZI1
YPKELNAIMESMLNK	NEK11	256	Q8NG66
QTATSLSKPQMIMYK	PIERCE2	46	H3BRN8
QMLKQPLTYRLSKEM	EXPH5	76	Q8NEV8
MTQYIRLTPDMQSKQ	LMAN2L	81	Q9H0V9
NLPKKTTDYAMLVTM	LRRC3B	196	Q96PB8
FLMYMKPKSQETLNS	OR13C5	256	Q8NGS8
PSKFQKIIYMNMISV	DPY19L2	366	Q6NUT2
ESLTKMYSIPKDKQM	HUWE1	241	Q7Z6Z7
LPVLEMYSKLKEQMS	EXOC6	136	Q8TAG9
FDNMPDYMILQELKK	PPTC7	226	Q8NI37
LEKEMQKMNPYKIDI	PRIM1	66	P49642
KLQSTTVMNPYMKLA	APOB	4541	P04114
PAYIKVQTNKMVMLS	CD8B2	26	A6NJW9
KATEALKKMYMEFPQ	GDE1	181	Q9NZC3
VIYINSPLPQKKMTM	ICE2	321	Q659A1
DMYNKMAKTQSQPIL	KCNB1	531	Q14721
YKMELLQIENMVLSP	GNPAT	371	O15228
EVMLLTYKSIPMQVD	DGKI	666	O75912
PAYIKVQTNKMVMLS	CD8B	26	P10966
DDYLVKEQLPDMQMK	POLQ	1496	O75417
ERIMQKYNLLPEKSM	UGT8	216	Q16880
QIVNGTMTLYKEAMK	DNAH7	2151	Q8WXX0
TMTLYKEAMKNLLPT	DNAH7	2156	Q8WXX0
RALYQKMVDKEMNPL	HUNK	271	P57058
LAMEEIYQKPFQTLM	ATL2	226	Q8NHH9
KIMESFKNMVPQQAL	ATP1A3	146	P13637
KLMEIITVENPKMPY	GBF1	501	Q92538
LMSLPIAKKYMSENK	C6orf89	106	Q6UWU4
ISKVMEMYQPSAVVL	HDAC2	246	Q92769
MTNQNTPEYMEKIKQ	HDAC2	351	Q92769
KQVLEKKMQTPMYTS	CCDC198	131	Q9NVL8
IMSIPNLRYMKESQV	DCTN4	311	Q9UJW0
KLHYMNIMAQVPLEK	SCNN1G	231	P51170
KPRMDQYFNQMEKIV	EIF4G3	946	O43432
PSKFQKIIYMNMISV	DPY19L2P2	176	Q6ZN68
MDNEKMKIPFTDIYI	LAMA4	1161	Q16363
LYLPAMKKQMAILDA	PLEKHA8P1	376	O95397
DMKTNMPIITSKRYQ	TSEN2	91	Q8NCE0
KEMQIVDVNYLIPVM	UTP20	1461	O75691
SENLNNEVMMKKYSP	RAB11FIP1	1201	Q6WKZ4
IYTQKQEPPKKVMMT	STEEP1	131	Q9H5V9
ALARQYMQMLPKEKQ	TES	121	Q9UGI8
MLKEKRQQSEKTFMP	SMC3	741	Q9UQE7
MKYNLMSKDNLIVPI	MOB4	196	Q9Y3A3
TLPAVYMAIKMSQLK	TDRD9	826	Q8NDG6
KQLEDYLTKILKMPM	PLD1	181	Q13393
ANILEKEKMYPMALL	SEL1L2	526	Q5TEA6
KNEEKPVQMMFKQST	SERPINB6	191	P35237
QLTMKMLESPSVAIY	KIAA1217	221	Q5T5P2
QMPKEYSQILQLHMK	ST8SIA6	371	P61647
SMDTMKQVYQIVKPL	NANS	161	Q9NR45
PLKNIMDVEMKLVYI	SPATA16	116	Q9BXB7
MEIATKEPMNPIKQY	PPA2	106	Q9H2U2
LMIMKTVYKGPNCIE	RIPK1	41	Q13546
DLSQMLKKMPQYQKE	STXBP1	326	P61764
DTMKVKMQTFPDLYR	SLC25A15	31	Q9Y619
EAIYLAKLTIQMMSP	STYX	171	Q8WUJ0
PSMEKKRTVYQMALN	SHANK1	806	Q9Y566
LQAMQMELQSPEYKL	ALK	1066	Q9UM73
PSNKDMYTEMLKSII	CENPBD1P	161	B2RD01
ISKKYKQHQPTDMVM	SPG11	2381	Q96JI7
RMAKYKLMNQASPEI	XIRP2	1406	A4UGR9
IQVEMKMPAYELKIV	PIH1D2	226	Q8WWB5
PDVQKKMLTAYDLMI	PLCL1	961	Q15111
ELEAKMPVIMKNSVY	PLEKHD1	411	A6NEE1
RKLMMKNEYIIPITS	RYR3	1621	Q15413
AVMEIMTKTIEYLQP	SH3GL2	46	Q99962
IFNQLEVKNPDSKMM	SRRM1	71	Q8IYB3
TMMIDNLKVDYLTKI	PIBF1	71	Q8WXW3
TIELMYSDKSMIQVP	USP25	576	Q9UHP3
VRMDPLTKPMQYKVV	USP15	481	Q9Y4E8
DKLITMTINEKQMYP	NF1	1976	P21359
MTINEKQMYPSIQAK	NF1	1981	P21359
MKEMKVSDIPQYSQL	NUP188	1216	Q5SRE5
AANNMKQVKDMYLIP	PHF3	1301	Q92576
YPNPMDKNVISVKIM	PRELID2	26	Q8N945
NEQTIMTMLQPRYSK	STAB2	516	Q8WWQ8
GVNPYILKKNMILMT	UQCC1	191	Q9NVA1
IMTTKNSNIYKMPLS	SLC14A1	351	Q13336
IRTMLYTPQEMKQII	RUVBL1	361	Q9Y265
LKKMMSNQYVPVKTH	UACA	851	Q9BZF9
METYKHLFLEKMPQL	USP34	1046	Q70CQ2
IKVEVQQPMIRYMQK	VAV2	176	P52735
QKYLIESNKQMMPLK	UGGT2	291	Q9NYU1
MSAPVYDSIKLMKDI	UGGT2	321	Q9NYU1
IAQMMVYVPKEEQLF	TOR3A	366	Q9H497
TKDLKNGMIIPSMYN	POSTN	176	Q15063
TEPLTMEKMSNVVKY	SOHLH2	121	Q9NX45
YVLQAMKHMEPQVKQ	DNAJC19	21	Q96DA6
PDYIMVMVANKKSQD	ZC3H14	31	Q6PJT7
LVTKYSQQMVKGMLQ	TRRAP	301	Q9Y4A5
KELYTMMTDKNISLI	USP8	186	P40818
MMELYEVQLHLPKFK	SERPINB10	281	P48595
QEMKTLFLNTEYLMP	TMEM234	46	Q8WY98
LAMLYKISNSMLDKP	TSHZ1	771	Q6ZSZ6
SIKIPSNRYNEMMKA	ZFYVE9	1136	O95405
IMKPLEYQFKSQIMS	TLE6	451	Q9H808
QKQMLVDMAKKLPVY	ZDHHC15	106	Q96MV8
FMKMPNIVSSKDYLV	LDHAL6A	71	Q6ZMR3
RIVQKYFLEMKNKMP	MYO1B	876	O43795
KMQQAGMALYKIVPK	NAA25	131	Q14CX7
VYEKNKMKIHIVPDM	NEB	4781	P20929