Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	heart development	NCOA6 KAT6A DVL1 APC SAV1 CPE NKX2-6 ECE1 MEF2A TENM4 EFNB2 BBS7 LRRC27 AGTR2 ALPK3 FOXC1 INVS	4.54e-06	757	128	17	GO:0007507
GeneOntologyBiologicalProcess	circulatory system development	NCOA6 CDX2 KAT6A DVL1 APC SAV1 CPE NKX2-6 ECE1 TYMP MEF2A CFD SLC39A12 TENM4 EFNB2 BBS7 LRRC27 ANGPTL4 AGTR2 ALPK3 PPP1R16B C5 FOXC1 INVS	7.94e-06	1442	128	24	GO:0072359
GeneOntologyBiologicalProcess	cardiac muscle tissue development	APC SAV1 NKX2-6 MEF2A TENM4 EFNB2 LRRC27 AGTR2 ALPK3 FOXC1	3.80e-05	327	128	10	GO:0048738
GeneOntologyBiologicalProcess	microtubule cytoskeleton organization	ATRX SUN1 DVL1 APC BBS2 EML2 FSIP2 SLC39A12 CEP250 RP1L1 SYNE2 PKHD1 CEP131 CDC20 UVRAG	4.11e-05	720	128	15	GO:0000226
GeneOntologyBiologicalProcess	embryonic heart tube development	DVL1 NKX2-6 ECE1 BBS7 FOXC1 INVS	4.44e-05	103	128	6	GO:0035050
GeneOntologyBiologicalProcess	striated muscle tissue development	APC SAV1 NKX2-6 MEF2A TENM4 EFNB2 LRRC27 AGTR2 ALPK3 FOXC1	6.56e-05	349	128	10	GO:0014706
GeneOntologyBiologicalProcess	nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration	SUN1 SYNE2	1.14e-04	3	128	2	GO:0021817
GeneOntologyBiologicalProcess	peptide hormone processing	CPE ECE1 ACE2 PCSK7	1.20e-04	41	128	4	GO:0016486
MousePheno	abnormal basal ganglion morphology	SOX1 GPR37 BBS2 TRIM67 SLC25A12 BBS7 SLC20A2 FOXC1	1.57e-06	106	108	8	MP:0006007
MousePheno	small lens	SOX1 NCOA6 POU2F1 FOXC1 MAF	2.67e-05	46	108	5	MP:0001306
Domain	IQ_motif_EF-hand-BS	IQSEC3 IQCN ADGB SCN10A CEP131 INVS	3.74e-05	90	129	6	IPR000048
Domain	IQ	IQSEC3 IQCN ADGB SCN10A CEP131 INVS	4.50e-05	93	129	6	PS50096
Domain	IQ	IQSEC3 IQCN SCN10A CEP131 INVS	1.31e-04	71	129	5	PF00612
Domain	Znf_FYVE_PHD	ATRX JADE3 KAT6A RFFL KMT2D WDFY3	5.52e-04	147	129	6	IPR011011
Domain	Quin_OxRdtase/zeta-crystal_CS	TP53I3 VAT1L	9.72e-04	7	129	2	IPR002364
Domain	QOR_ZETA_CRYSTAL	TP53I3 VAT1L	9.72e-04	7	129	2	PS01162
Domain	WD40_repeat_dom	UBR4 BBS2 EML2 DCAF12L2 WDR91 BBS7 WDFY3 CDC20	1.08e-03	297	129	8	IPR017986
Domain	-	ATRX JADE3 KAT6A MARCHF6 TRIM49D1 SIAH2 RFFL KMT2D TRIM67 WDFY3	1.12e-03	449	129	10	3.30.40.10
Domain	ATP_grasp_subdomain_2	SUCLA2 GSS SYN1	1.26e-03	31	129	3	IPR013816
Domain	Znf_RING/FYVE/PHD	ATRX JADE3 KAT6A MARCHF6 TRIM49D1 SIAH2 RFFL KMT2D TRIM67 WDFY3	1.33e-03	459	129	10	IPR013083
Domain	Znf_RING	ATRX KAT6A MARCHF6 TRIM49D1 SIAH2 RFFL KMT2D TRIM67	1.94e-03	326	129	8	IPR001841
Domain	IQ	IQCN ADGB CEP131 INVS	2.40e-03	81	129	4	SM00015
Domain	ZIP	SLC39A12 SLC39A5	4.08e-03	14	129	2	IPR003689
Domain	Zip	SLC39A12 SLC39A5	4.08e-03	14	129	2	PF02535
Domain	PreATP-grasp_dom	GSS SYN1	4.08e-03	14	129	2	IPR016185
Domain	ZF_PHD_2	ATRX JADE3 KAT6A KMT2D	4.26e-03	95	129	4	PS50016
Domain	ZF_PHD_1	ATRX JADE3 KAT6A KMT2D	4.42e-03	96	129	4	PS01359
Domain	Carbonic_anhydrase_a-class	CA11 CA10	4.69e-03	15	129	2	IPR023561
Domain	ALPHA_CA_1	CA11 CA10	4.69e-03	15	129	2	PS00162
Domain	tRNAsynth_Ia_anticodon-bd	LARS1 CEP131	4.69e-03	15	129	2	IPR009080
Domain	-	SUCLA2 SYN1	4.69e-03	15	129	2	3.30.1490.20
Domain	RING	ATRX KAT6A TRIM49D1 SIAH2 RFFL KMT2D TRIM67	5.31e-03	305	129	7	SM00184
Domain	PKS_ER	TP53I3 VAT1L	5.33e-03	16	129	2	IPR020843
Domain	ADH_N	TP53I3 VAT1L	5.33e-03	16	129	2	PF08240
Domain	PKS_ER	TP53I3 VAT1L	5.33e-03	16	129	2	SM00829
Domain	ADH_N	TP53I3 VAT1L	5.33e-03	16	129	2	IPR013154
Domain	Carb_anhydrase	CA11 CA10	6.02e-03	17	129	2	PF00194
Domain	CarboxyPept-like_regulatory	CPE TENM4	6.02e-03	17	129	2	IPR008969
Domain	Carb_anhydrase	CA11 CA10	6.02e-03	17	129	2	SM01057
Domain	-	CA11 CA10	6.02e-03	17	129	2	3.10.200.10
Domain	ALPHA_CA_2	CA11 CA10	6.02e-03	17	129	2	PS51144
Domain	Carbonic_anhydrase_a	CA11 CA10	6.02e-03	17	129	2	IPR001148
Domain	-	TP53I3 VAT1L	6.74e-03	18	129	2	3.90.180.10
Domain	ATP_grasp_subdomain_1	SUCLA2 SYN1	6.74e-03	18	129	2	IPR013815
Domain	-	SUCLA2 SYN1	6.74e-03	18	129	2	3.30.470.20
Pubmed	Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons.	IRF2BP2 IRS4 UBR4 MARCHF6 ASAP3 ECE1 SUCLA2 SYNE2 SCN10A SYN1	4.32e-07	322	131	10	26514267
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	PRUNE2 NCOA6 IRS4 UBR4 ASAP3 GLIS3 PRDM4 ZNF532 SCN10A NUMB UVRAG	7.63e-07	430	131	11	35044719
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	NCOA6 TMEM158 UBR4 KAT6A DVL1 EML2 SIAH2 ECE1 NHSL1 SEPHS2 KMT2D NADK CEP131 WDFY3 DOT1L UVRAG	4.38e-06	1105	131	16	35748872
Pubmed	The centriolar satellite protein AZI1 interacts with BBS4 and regulates ciliary trafficking of the BBSome.	BBS2 BBS7 CEP131	8.43e-06	11	131	3	24550735
Pubmed	Loss of Usp9x disrupts cell adhesion, and components of the Wnt and Notch signaling pathways in neural progenitors.	SOX1 DVL1 APC NUMB	9.19e-06	35	131	4	28808228
Pubmed	The tumor suppressor CDX2 opposes pro-metastatic biomechanical modifications of colon cancer cells through organization of the actin cytoskeleton.	CDX2 APC	1.41e-05	2	131	2	27816490
Pubmed	Colonic polyposis caused by mTOR-mediated chromosomal instability in Apc+/Delta716 Cdx2+/- compound mutant mice.	CDX2 APC	1.41e-05	2	131	2	14625550
Pubmed	TIMAP-protein phosphatase 1-complex controls endothelin-1 production via ECE-1 dephosphorylation.	ECE1 PPP1R16B	1.41e-05	2	131	2	26806547
Pubmed	Elevated Adipsin and Reduced C5a Levels in the Maternal Serum and Follicular Fluid During Implantation Are Associated With Successful Pregnancy in Obese Women.	CFD C5	1.41e-05	2	131	2	35909516
Pubmed	Colon adenocarcinoma-derived cells possessing stem cell function can be modulated using renin-angiotensin system inhibitors.	ACE2 AGTR2	1.41e-05	2	131	2	34428252
Pubmed	Muscle mTORC1 suppression by IL-6 during cancer cachexia: a role for AMPK.	APC CRTC1	1.41e-05	2	131	2	23531613
Pubmed	cDNA sequence of human carbonic anhydrase-related protein, CA-RP X: mRNA expressions of CA-RP X and XI in human brain.	CA11 CA10	1.41e-05	2	131	2	11311946
Pubmed	Nociceptor-expressed ephrin-B2 regulates inflammatory and neuropathic pain.	EFNB2 SCN10A	1.41e-05	2	131	2	21059214
Pubmed	Long-term physical activity modulates adipsin and ANGPTL4 serum levels, a potential link to exercise-induced metabolic changes.	CFD ANGPTL4	1.41e-05	2	131	2	34309331
Pubmed	CA10 and CA11 negatively regulate neuronal activity-dependent growth of gliomas.	CA11 CA10	1.41e-05	2	131	2	30636076
Pubmed	The Parkinson's disease-associated GPR37 receptor interacts with striatal adenosine A2A receptor controlling its cell surface expression and function in vivo.	GPR37 ADORA2A	1.41e-05	2	131	2	28842709
Pubmed	Inhibition of indoleamine 2,3-dioxygenase 1 expression alters immune response in colon tumor microenvironment in mice.	IDO1 APC	1.41e-05	2	131	2	26033215
Pubmed	Chronic adenosine A2A receptor blockade induces locomotor sensitization and potentiates striatal LTD IN GPR37-deficient mice.	GPR37 ADORA2A	1.41e-05	2	131	2	30578680
Pubmed	A novel IRF2BP2::CDX2 Gene fusion in digital intravascular myoepithelioma of soft tissue: An enigma!	IRF2BP2 CDX2	1.41e-05	2	131	2	36448218
Pubmed	Functional proteomics mapping of a human signaling pathway.	NCOA6 ATRX UBR4 FNBP4 PSMD1 SIAH2 PRDM4 KMT2D PELP1 CEP250 INVS	1.57e-05	591	131	11	15231748
Pubmed	Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.	IRF2BP2 NCOA6 POU2F1 KMT2D FOXC1	1.61e-05	83	131	5	28794006
Pubmed	Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.	UBR4 LARS1 NHSL1 TENM4 RBM27 ALPK3	2.61e-05	153	131	6	10718198
Pubmed	Genomic analysis of mouse retinal development.	LHX4 GPR37 MYO1H DVL1 APC BBS2 RFFL CPE ECE1 MEF2A SLC25A12 BBS7 RP1L1 WDFY3	2.79e-05	1006	131	14	15226823
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	IRS4 UBR4 DVL1 APC PSMD1 CRTC1 KMT2D ZNF532 CEP131	3.12e-05	418	131	9	34709266
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	USP36 NCOA6 JADE3 SUN1 MARCHF6 LARS1 FNBP4 CRTC1 ZNF532 RBM27	3.40e-05	529	131	10	14621295
Pubmed	The Cdx2 homeobox gene suppresses intestinal tumorigenesis through non-cell-autonomous mechanisms.	CDX2 APC	4.21e-05	3	131	2	29439001
Pubmed	De novo point mutations in patients diagnosed with ataxic cerebral palsy.	SPTBN2 KCNC3	4.21e-05	3	131	2	25981959
Pubmed	Suppression of colonic polyposis by homeoprotein CDX2 through its nontranscriptional function that stabilizes p27Kip1.	CDX2 APC	4.21e-05	3	131	2	21224344
Pubmed	Inversin, the gene product mutated in nephronophthisis type II, functions as a molecular switch between Wnt signaling pathways.	DVL1 INVS	4.21e-05	3	131	2	15852005
Pubmed	Identification of a novel Bardet-Biedl syndrome protein, BBS7, that shares structural features with BBS1 and BBS2.	BBS2 BBS7	4.21e-05	3	131	2	12567324
Pubmed	Triallelic inheritance in Bardet-Biedl syndrome, a Mendelian recessive disorder.	BBS2 BBS7	4.21e-05	3	131	2	11567139
Pubmed	The Role of ACE, ACE2, and AGTR2 Polymorphisms in COVID-19 Severity and the Presence of COVID-19-Related Retinopathy.	ACE2 AGTR2	4.21e-05	3	131	2	35885894
Pubmed	miR-23a promotes the transition from indolent to invasive colorectal cancer.	APC MLH3	4.21e-05	3	131	2	22628407
Pubmed	Binding of APC and dishevelled mediates Wnt5a-regulated focal adhesion dynamics in migrating cells.	DVL1 APC	4.21e-05	3	131	2	20224554
Pubmed	The tumor suppressor adenomatous polyposis coli and caudal related homeodomain protein regulate expression of retinol dehydrogenase L.	CDX2 APC	4.21e-05	3	131	2	15190067
Pubmed	The inner nuclear membrane protein Sun1 mediates the anchorage of Nesprin-2 to the nuclear envelope.	SUN1 SYNE2	4.21e-05	3	131	2	16079285
Pubmed	Regulation of the tumor suppressor homeogene Cdx2 by HNF4α in intestinal cancer.	CDX2 APC	4.21e-05	3	131	2	22986531
Pubmed	Fine-tuning and autoregulation of the intestinal determinant and tumor suppressor homeobox gene CDX2 by alternative splicing.	CDX2 APC	4.21e-05	3	131	2	28862703
Pubmed	Dynamics and molecular interactions of linker of nucleoskeleton and cytoskeleton (LINC) complex proteins.	SUN1 SYNE2	4.21e-05	3	131	2	19843581
Pubmed	Histone methyltransferase MLL4 controls myofiber identity and muscle performance through MEF2 interaction.	MEF2A KMT2D	4.21e-05	3	131	2	32544095
Pubmed	Thyroid Carcinomas That Occur in Familial Adenomatous Polyposis Patients Recurrently Harbor Somatic Variants in APC, BRAF, and KTM2D.	APC KMT2D	4.21e-05	3	131	2	32024448
Pubmed	Dental Anomalies in Ciliopathies: Lessons from Patients with BBS2, BBS7, and EVC2 Mutations.	BBS2 BBS7	4.21e-05	3	131	2	36672825
Pubmed	Transcriptional regulation of the intestinal nuclear bile acid farnesoid X receptor (FXR) by the caudal-related homeobox 2 (CDX2).	CDX2 APC	4.21e-05	3	131	2	25138215
Pubmed	Developmental expression of carbonic anhydrase-related proteins VIII, X, and XI in the human brain.	CA11 CA10	4.21e-05	3	131	2	12044474
Pubmed	Mouse model of colonic adenoma-carcinoma progression based on somatic Apc inactivation.	CDX2 APC	4.21e-05	3	131	2	17942902
Pubmed	Possible role of angiotensin-converting enzyme 2 and activation of angiotensin II type 2 receptor by angiotensin-(1-7) in improvement of vascular remodeling by angiotensin II type 1 receptor blockade.	ACE2 AGTR2	4.21e-05	3	131	2	24379178
Pubmed	Regulation of APC and AXIN2 expression by intestinal tumor suppressor CDX2 in colon cancer cells.	CDX2 APC	4.21e-05	3	131	2	23393221
Pubmed	Cdx1 and Cdx2 function as tumor suppressors.	CDX2 APC	4.21e-05	3	131	2	25320087
Pubmed	Molecular architecture of the Bardet-Biedl syndrome protein 2-7-9 subcomplex.	BBS2 BBS7	4.21e-05	3	131	2	31530639
Pubmed	Membrane localization of membrane type 5 matrix metalloproteinase by AMPA receptor binding protein and cleavage of cadherins.	MMP24 SYN1	4.21e-05	3	131	2	16495457
Pubmed	cDNA cloning and developmental expression of murine carbonic anhydrase-related proteins VIII, X, and XI.	CA11 CA10	4.21e-05	3	131	2	12531530
Pubmed	Congenital Hepatic Fibrosis Overview ─ RETIRED CHAPTER, FOR HISTORICAL REFERENCE ONLY	BBS2 BBS7 PKHD1 INVS	4.52e-05	52	131	4	20301743
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	PRUNE2 ATRX KAT6A FNBP4 PSMD1 IQCN SUCLA2 MEF2A ERGIC1 EFNB2 ZNF532 LRRC27 NUMB XYLB INVS PDZD2 MAF	4.61e-05	1489	131	17	28611215
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	NCOA6 IRS4 SPTBN2 DVL1 FNBP4 ADD3 KMT2D RBM27 NUMB DOT1L	4.64e-05	549	131	10	38280479
Pubmed	Synergistic activation of the Wnt signaling pathway by Dvl and casein kinase Iepsilon.	DVL1 APC	8.41e-05	4	131	2	11425858
Pubmed	SUN1 interacts with nuclear lamin A and cytoplasmic nesprins to provide a physical connection between the nuclear lamina and the cytoskeleton.	SUN1 SYNE2	8.41e-05	4	131	2	16648470
Pubmed	IDO1+ Paneth cells promote immune escape of colorectal cancer.	IDO1 APC	8.41e-05	4	131	2	32444775
Pubmed	Axin-dependent phosphorylation of the adenomatous polyposis coli protein mediated by casein kinase 1epsilon.	DVL1 APC	8.41e-05	4	131	2	11487578
Pubmed	SARS-CoV-2 spike protein enhances MAP4K3/GLK-induced ACE2 stability in COVID-19.	UBR4 ACE2	8.41e-05	4	131	2	35894122
Pubmed	Differential renal effects of candesartan at high and ultra-high doses in diabetic mice-potential role of the ACE2/AT2R/Mas axis.	ACE2 AGTR2	8.41e-05	4	131	2	27612496
Pubmed	Coupling of the nucleus and cytoplasm: role of the LINC complex.	SUN1 SYNE2	8.41e-05	4	131	2	16380439
Pubmed	Novel roles for MLH3 deficiency and TLE6-like amplification in DNA mismatch repair-deficient gastrointestinal tumorigenesis and progression.	APC MLH3	8.41e-05	4	131	2	18551179
Pubmed	Multifactorial inheritance of neural tube defects: localization of the major gene and recognition of modifiers in ct mutant mice.	DVL1 TYRP1	8.41e-05	4	131	2	8054974
Pubmed	Outer nuclear membrane protein Kuduk modulates the LINC complex and nuclear envelope architecture.	SUN1 SYNE2	8.41e-05	4	131	2	28716842
Pubmed	Defining the layers of a sensory cilium with STORM and cryoelectron nanoscopy.	BBS2 BBS7	8.41e-05	4	131	2	31690665
Pubmed	LINC complexes mediate the positioning of cone photoreceptor nuclei in mouse retina.	SUN1 SYNE2	8.41e-05	4	131	2	23071752
Pubmed	Nesprins, but not sun proteins, switch isoforms at the nuclear envelope during muscle development.	SUN1 SYNE2	8.41e-05	4	131	2	20108321
Pubmed	A miR-34a-Numb Feedforward Loop Triggered by Inflammation Regulates Asymmetric Stem Cell Division in Intestine and Colon Cancer.	APC NUMB	8.41e-05	4	131	2	26849305
Pubmed	The SUN2-nesprin-2 LINC complex and KIF20A function in the Golgi dispersal.	SUN1 SYNE2	8.41e-05	4	131	2	33686165
Pubmed	Angiotensin-converting enzyme 2 protects from severe acute lung failure.	ACE2 AGTR2	8.41e-05	4	131	2	16001071
Pubmed	POU homeodomain protein Oct-1 functions as a sensor for cyclic AMP.	CDX2 POU2F1	8.41e-05	4	131	2	19617623
Pubmed	Intracellular complement C5a/C5aR1 stabilizes β-catenin to promote colorectal tumorigenesis.	APC C5	8.41e-05	4	131	2	35649359
Pubmed	TRIM67 Activates p53 to Suppress Colorectal Cancer Initiation and Progression.	APC TRIM67	8.41e-05	4	131	2	31239268
Pubmed	Oct1/Pou2f1 is selectively required for colon regeneration and regulates colon malignancy.	APC POU2F1	8.41e-05	4	131	2	31059499
Pubmed	Human transcription factor protein interaction networks.	IRF2BP2 NCOA6 IRS4 LHX4 ATRX UBR4 LARS1 PSMD1 POU2F1 MEF2A KMT2D RBM27 SYNE2 CEP131 DOT1L FOXC1	9.83e-05	1429	131	16	35140242
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	NCOA6 IRS4 APC CRTC1 FSIP2 NHSL1 SYNE2 NADK NUMB CEP131 CDC20 UVRAG	1.06e-04	861	131	12	36931259
Pubmed	Signaling across the synapse: a role for Wnt and Dishevelled in presynaptic assembly and neurotransmitter release.	DVL1 SYN1	1.40e-04	5	131	2	16818724
Pubmed	Mammalian SUN protein interaction networks at the inner nuclear membrane and their role in laminopathy disease processes.	SUN1 SYNE2	1.40e-04	5	131	2	19933576
Pubmed	Direct regulation of FNIP1 and FNIP2 by MEF2 sustains MTORC1 activation and tumor progression in pancreatic cancer.	FNIP2 MEF2A	1.40e-04	5	131	2	37772772
Pubmed	DIX domains of Dvl and axin are necessary for protein interactions and their ability to regulate beta-catenin stability.	DVL1 APC	1.40e-04	5	131	2	10330181
Pubmed	Let-7b-5p inhibits colon cancer progression by prohibiting APC ubiquitination degradation and the Wnt pathway by targeting NKD1.	DVL1 APC	1.40e-04	5	131	2	36445120
Pubmed	LINC complexes form by binding of three KASH peptides to domain interfaces of trimeric SUN proteins.	SUN1 SYNE2	1.40e-04	5	131	2	22632968
Pubmed	Wnt regulates axon behavior through changes in microtubule growth directionality: a new role for adenomatous polyposis coli.	DVL1 APC	1.40e-04	5	131	2	18716223
Pubmed	Activation of the human anaphase-promoting complex by proteins of the CDC20/Fizzy family.	APC CDC20	1.40e-04	5	131	2	9811605
Pubmed	Serotonin reduction in post-acute sequelae of viral infection.	IDO1 ACE2	1.40e-04	5	131	2	37848036
Pubmed	Structural requirements for the assembly of LINC complexes and their function in cellular mechanical stiffness.	SUN1 SYNE2	1.40e-04	5	131	2	18396275
Pubmed	A new autosomal dominant Peters' anomaly phenotype expanding the anterior segment dysgenesis spectrum.	FOXC1 MAF	1.40e-04	5	131	2	18616618
Pubmed	The absence of BBSome function decreases synaptogenesis and causes ectopic synapse formation in the retina.	BBS2 BBS7	1.40e-04	5	131	2	32433491
Pubmed	Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3beta and beta-catenin and promotes GSK-3beta-dependent phosphorylation of beta-catenin.	DVL1 APC	1.40e-04	5	131	2	9482734
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	IRF2BP2 NCOA6 UBR4 DCAF12L2 KMT2D BBS7 CDIPT SYNE2 C5 WDFY3	1.59e-04	638	131	10	31182584
Pubmed	Maps from two interspecific backcross DNA panels available as a community genetic mapping resource.	LHX4 DVL1 CFD C5	1.62e-04	72	131	4	8075499
Pubmed	Analysis of 30 genes (355 SNPS) related to energy homeostasis for association with adiposity in European-American and Yup'ik Eskimo populations.	BBS2 CPE BBS7	1.97e-04	30	131	3	19077438
Pubmed	SPTAN1/NUMB axis senses cell density to restrain cell growth and oncogenesis through Hippo signaling.	SAV1 NUMB	2.09e-04	6	131	2	37843276
Pubmed	BBS proteins interact genetically with the IFT pathway to influence SHH-related phenotypes.	BBS2 BBS7	2.09e-04	6	131	2	22228099
Pubmed	Coactivator as a target gene specificity determinant for histone H3 lysine 4 methyltransferases.	NCOA6 KMT2D	2.09e-04	6	131	2	17021013
Pubmed	Interactions among related genes of renin-angiotensin system associated with type 2 diabetes.	ACE2 AGTR2	2.09e-04	6	131	2	20592051
Pubmed	Tissue-specific regulation of ACE/ACE2 and AT1/AT2 receptor gene expression by oestrogen in apolipoprotein E/oestrogen receptor-alpha knock-out mice.	ACE2 AGTR2	2.09e-04	6	131	2	18192335
Pubmed	The checkpoint protein MAD2 and the mitotic regulator CDC20 form a ternary complex with the anaphase-promoting complex to control anaphase initiation.	APC CDC20	2.09e-04	6	131	2	9637688
Pubmed	Wnt-5a inhibits the canonical Wnt pathway by promoting GSK-3-independent beta-catenin degradation.	APC SIAH2	2.09e-04	6	131	2	12952940
Pubmed	Functional Complexes of Angiotensin-Converting Enzyme 2 and Renin-Angiotensin System Receptors: Expression in Adult but Not Fetal Lung Tissue.	ACE2 AGTR2	2.09e-04	6	131	2	33339432
CoexpressionAtlas	FacebaseRNAseq_e9.5_Mandibular Arch_top-relative-expression-ranked_1000_k-means-cluster#4	ATRX KAT6A BBS2 POU2F1 SUCLA2 SYNE2 NUMB XYLB WDFY3	2.87e-06	203	123	9	Facebase_RNAseq_e9.5_Mandibular Arch_1000_K4
CoexpressionAtlas	FacebaseRNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_500_k-means-cluster#4	CA11 IRS4 GLIS3 VAT1L MAF	5.45e-06	44	123	5	Facebase_RNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_500_K4
CoexpressionAtlas	DevelopingGonad_e16.5_epididymis_emap-29702_top-relative-expression-ranked_1000	CA11 IRS4 ATRX FNBP4 TENT5C ECE1 MEF2A ADD3 ACE2 TENM4 SYNE2 CPEB4 AGTR2 WDFY3 MAF	5.31e-05	790	123	15	gudmap_developingGonad_e16.5_epididymis_1000
ToppCell	NS-critical-d_0-4-Epithelial-unknown_epithelial\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	NCOA6 CA10 ACE2 FAT2 CEP250 ANGPTL4 ALPK3	6.23e-07	166	131	7	dd02bbe4af609c6348dc92417254f4740f2900a8
ToppCell	wk_15-18-Mesenchymal-Chondrocyte-ASPN+_chondrocyte\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	IQSEC3 IQCN SLC25A12 DMKN ANKDD1A WDFY3 FOXC1	9.95e-07	178	131	7	a55130670aa95a87b833dd3cd2de461d779e4c06
ToppCell	COVID-19-kidney-PCT-S1\|kidney / Disease (COVID-19 only), tissue and cell type	PRUNE2 GLIS3 CPE ACE2 SYNE2 PKHD1 XYLB	1.24e-06	184	131	7	51ed1ebfdef45149541917c66cbacad87072e51f
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 CPE WDR91 SYNE2 PKHD1 NOVA1 PDZD2	1.34e-06	186	131	7	f0c8de4f6ae9047b9108a47a2af8c5f42bc103b0
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 GLIS3 WDR91 SYNE2 PKHD1 NOVA1 PDZD2	1.43e-06	188	131	7	af740fa78542438fdff627ea1f74f4eee43316be
ToppCell	facs-Heart-LA-3m-Endothelial-endothelial_cell_of_endocardium\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTX4 TMEM158 CPE ECE1 NHSL1 EFNB2 FOXC1	1.65e-06	192	131	7	14a816ef116aa992f86edab411f043cf7d07fe04
ToppCell	facs-Heart-LA-3m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTX4 TMEM158 CPE ECE1 NHSL1 EFNB2 FOXC1	1.65e-06	192	131	7	847822514d747a21d5eb40e04ba9a023fd32bd65
ToppCell	P15-Endothelial-large_vessel_endothelial_cell\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	TMEM158 CPE ECE1 TM6SF1 EFNB2 FOXC1 PDZD2	1.71e-06	193	131	7	5f9a7cd5f8eb9ac294cdb50518fedf872f3f78f5
ToppCell	Dendritic_Cells-IPF_03\|World / lung cells shred on cell class, cell subclass, sample id	IDO1 TYMP TENM4 ASGR2 RP1L1 SYN1	5.72e-06	151	131	6	e089bf197ed60e7243160521d4390d4b40a3832b
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 ACE2 SYNE2 XYLB SLC39A5 PDZD2	1.37e-05	176	131	6	1595dbeee336a81e581325d63208ec6262664ee9
ToppCell	COVID-19-kidney-PCT-S1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PRUNE2 GLIS3 ACE2 SYNE2 PKHD1 XYLB	1.71e-05	183	131	6	6878d14026c3df6aa12e45dfad94b32fa9d9b0b7
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 ACE2 TENM4 SYNE2 XYLB PDZD2	1.76e-05	184	131	6	9434731f651820b05335085582960f08fbf895de
ToppCell	facs-Large_Intestine-Proximal-24m-Epithelial-enteroendocrine_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CPE ADGB ADORA2A ACE2 GPR142 SYN1	1.82e-05	185	131	6	2a8104f610fa5ce618f8105521616722462a0d42
ToppCell	Smart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte\|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	IRF2BP2 TENM4 ASGR2 CPEB4 SCN10A PKHD1	1.88e-05	186	131	6	23b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCell	droplet-Heart-nan-3m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATRX APC ECE1 EFNB2 SYNE2 PPP1R16B	1.88e-05	186	131	6	0ae5fbe9f210cb25092394267e1d3d6ed05627b8
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 TENM4 SYNE2 ANGPTL4 PKHD1 PDZD2	1.88e-05	186	131	6	b1edc341d6684b347dc9e21b34f62f51d095d735
ToppCell	facs-Lung-ENDOMUCIN-18m-Endothelial-Artery_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 TMEM158 CPE CFD EFNB2 FOXC1	1.88e-05	186	131	6	5302399825f213d105ac70b91366a4513b732838
ToppCell	PBMC-Mild-cDC_5\|Mild / Compartment, Disease Groups and Clusters	ZNF787 MARCHF6 TENT5C TM6SF1 EFNB2 METTL22	1.93e-05	187	131	6	0afef5baf3752314dbfb024790347d5e51f9b84b
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 IQSEC3 PKHD1 PPP1R16B XYLB PDZD2	1.93e-05	187	131	6	3ae3b8de1a195d4d5057cf3c64fcdb5f48681ce5
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 SYNE2 PKHD1 PPP1R16B XYLB PDZD2	1.93e-05	187	131	6	dcf6475ece5b34d9d58a0d1f51c18acedb19c119
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 WDR91 SYNE2 PKHD1 NOVA1 PDZD2	1.93e-05	187	131	6	c31130fc2f9f882944b2ba366a034a03f051c4b9
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 SYNE2 PKHD1 PPP1R16B XYLB PDZD2	1.93e-05	187	131	6	f1356273bd3587b6883295edf15cb9cdb706c057
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 CPE SYNE2 PKHD1 WDFY3 FOXC1	2.05e-05	189	131	6	904b8337e2cabac2f0bf5dad5598fc429581ed81
ToppCell	facs-Lung-3m-Endothelial-arterial_endothelial\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PRUNE2 TMEM158 CPE ECE1 EFNB2 FOXC1	2.18e-05	191	131	6	6e6b2cb390cc5cd0356924a2c36fbe5b5bd5966c
ToppCell	facs-Lung-3m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PRUNE2 TMEM158 CPE ECE1 EFNB2 FOXC1	2.18e-05	191	131	6	482db995930346be69072ace2fd78fd453e97fb5
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 CPE SYNE2 PKHD1 WDFY3 FOXC1	2.38e-05	194	131	6	8ddcaaf24cee6e30d5be52c0cbf778cfba309c53
ToppCell	Control-Myeloid-Migratory_DC\|Myeloid / Condition, Lineage and Cell class	FNIP2 IDO1 TENT5C ADORA2A PPP1R16B SLAMF7	2.45e-05	195	131	6	9f1ad04abc6a6c5e093ea24b60732871b1fad5a4
ToppCell	CV-Moderate-6\|Moderate / Virus stimulation, Condition and Cluster	IRF2BP2 ATRX TENT5C TYMP SLAMF7 MAF	2.45e-05	195	131	6	2b8a72d7e755b9655c7a496000d10ff06e50862b
ToppCell	CV-Moderate-6\|CV / Virus stimulation, Condition and Cluster	IRF2BP2 ATRX TENT5C SIAH2 SLAMF7 MAF	2.52e-05	196	131	6	7bced0cc2112697593c478fa291b8ed3941fb811
ToppCell	5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.1.3\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ECE1 MEF2A ADD3 EFNB2 SYNE2 ANGPTL4	2.67e-05	198	131	6	d5990cab01de6e6f3757f5a50ef70ced711bb1fa
ToppCell	Parenchymal-NucSeq-Endothelial-Endothelia_vascular-VE_pulmonary_arterial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	IDO1 ECE1 TM6SF1 EFNB2 ANGPTL4 FOXC1	2.67e-05	198	131	6	002424b24dacac553e02d0f764a6e8a1e567b9df
ToppCell	356C-Fibroblasts-Fibroblast-F-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	FAM114A1 TP53I3 ADD3 ERGIC1 CFD NOVA1	2.74e-05	199	131	6	beca4c7eb29ac771fd37f30cd23d4dce4afcfff8
ToppCell	356C-Fibroblasts-Fibroblast-F\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	FAM114A1 TP53I3 ADD3 ERGIC1 CFD NOVA1	2.74e-05	199	131	6	cd3ab9a75b40e0d417d53b3d8756fc9bed30ac83
ToppCell	VE-CD4-antiviral_CD4\|VE / Condition, Cell_class and T cell subcluster	ECE1 TYMP SYNE2 PARP9 HERC5 MAF	2.74e-05	199	131	6	056a0538ca5e825ae6195b4c76c208708a014533
ToppCell	ILEUM-inflamed-(8)_Fibroblast-(8)_Fibroblasts\|(8)_Fibroblast / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	ATRX CRTC1 ADD3 CFD NOVA1 MAF	2.74e-05	199	131	6	615f20bf136dfef53b072667cf0e4df6a1017e05
ToppCell	ILEUM-non-inflamed-(8)_Fibroblast-(8)_Fibroblasts\|(8)_Fibroblast / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	IDO1 CRTC1 ADD3 CFD NOVA1 MAF	2.74e-05	199	131	6	56d72da6a5fab9cbb2975fe6f87a631debaba6a8
ToppCell	LPS_only-Endothelial-Endothelial-Activated_Alv_Cap\|LPS_only / Treatment groups by lineage, cell group, cell type	IDO1 KAT6A ECE1 SYNE2 HERC5 NOVA1	2.82e-05	200	131	6	edb64556b3fefe3144f73b6efe23b9ffd34091d2
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial-Activated_Alv_Cap\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	IDO1 KAT6A MEF2A SYNE2 HERC5 NOVA1	2.82e-05	200	131	6	89821a264e872ed53e08e9d3609d5cc5c314503e
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Vein\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	ASAP3 CPE ECE1 CA10 MEF2A FOXC1	2.82e-05	200	131	6	b3f93b71589251197cde96b7bc6d065c106f61cd
ToppCell	Parenchymal-10x3prime_v2-Endothelial-Endothelia_vascular-VE_pulmonary_arterial\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	IDO1 ECE1 TM6SF1 EFNB2 ANGPTL4 CEP131	2.82e-05	200	131	6	e90ca26643f8496bdd6672c327da9855490d1aa8
ToppCell	Severe-Myeloid-Macrophages-FCN1_high\|Severe / Condition, Lineage, Cell class and cell subclass	IDO1 TYMP CFD ASGR2 SLAMF7 HERC5	2.82e-05	200	131	6	449623d6786e30d493f68156b3f1ee8caf9265a6
ToppCell	NS-critical-d_16-33-Myeloid-Monocyte-derived_Macrophage\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	FNIP2 IDO1 TRIM49D1 PARP9 HERC5	8.98e-05	153	131	5	859de35b24c5d7d73be1c213b90b43362ee2e0eb
ToppCell	facs-Marrow-Granulocytes-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TENT5C VAT1L TTC23 CPEB4 SLC39A5	1.11e-04	160	131	5	56e6f4b82b5dc41c45f9d253c2db314a6f702b84
ToppCell	facs-Marrow-Granulocytes-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TENT5C VAT1L TTC23 CPEB4 SLC39A5	1.11e-04	160	131	5	bb1b966fb9e801db15e67d03e49db4609d6f935a
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GLIS3 WDR91 SYNE2 PKHD1 PDZD2	1.24e-04	164	131	5	1cb5fbd7050650047ad6f2ca792118e98d58d22b
ToppCell	Adult-Immune-dendritic_cell\|Adult / Lineage, Cell type, age group and donor	TTC24 IDO1 TEX15 PPP1R16B SLAMF7	1.28e-04	165	131	5	073f52698dac1fe4edd7410865f81b30e1c7196a
ToppCell	droplet-Thymus-nan-21m-Myeloid-Plasma_cells_and_B_cells\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TENT5C ERGIC1 CFD TTC23 SLAMF7	1.28e-04	165	131	5	21a82a975f550080b6674750b06212205cd16742
ToppCell	facs-Marrow-B-cells-18m-Hematologic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TTC24 IDO1 TENT5C CFD SLAMF7	1.28e-04	165	131	5	361a605d8f833d9ec54b120480dce397da35f9c3
ToppCell	normal_Lymph_Node-Myeloid_cells-Pleural_Mac\|Myeloid_cells / Location, Cell class and cell subclass	TYMP RBM27 ASGR2 PARP9 HERC5	1.35e-04	167	131	5	820472887f43b42ae7e44513ca3d5465fb4f71a7
ToppCell	Control-Myeloid-MoAM1,_IL1R2\|Myeloid / Condition, Lineage and Cell class	IDO1 TYMP ANKDD1A SLAMF7 HERC5	1.35e-04	167	131	5	6e5140527437193f441ca96893b9a00d346614f3
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 IQSEC3 XYLB PDZD2 MAF	1.39e-04	168	131	5	fa0d251693935116adf633d02b7ec4a295100865
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c04-ANXA2\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	IRF2BP2 EML2 METTL22 PDZD2 MAF	1.43e-04	169	131	5	01a24a8817628125bd004b2be68ffa62c7111f6e
ToppCell	356C-Myeloid-Dendritic-cDC_activated\|Dendritic / Donor, Lineage, Cell class and subclass (all cells)	IDO1 JADE3 SIAH2 ADORA2A PPP1R16B	1.47e-04	170	131	5	513d9036aa41d4d902da8baa66a66206abb6f3b0
ToppCell	E16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	IDO1 TMEM158 CPE ECE1 FOXC1	1.47e-04	170	131	5	af8b56555cbd5a1016ab9ec2ce88225c58c89648
ToppCell	10x3'2.3-week_12-13-Myeloid_DC-DC-DC1\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	IDO1 PYROXD2 KCNC3 ANKDD1A SLAMF7	1.51e-04	171	131	5	04346d4eb726875e3537e215ea081a0318ca4ddd
ToppCell	PND28-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TMEM158 CPE ECE1 LRRC27 FOXC1	1.55e-04	172	131	5	fc092a0631555d79e00ef9890cbd806e15bca2d4
ToppCell	PND28-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TMEM158 CPE ECE1 LRRC27 FOXC1	1.55e-04	172	131	5	745725bd10c82017d678463b8fef0d2dcf09a8fd
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c12-FOXP3\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	RFFL SYNE2 PPP1R16B HERC5 FOXC1	1.55e-04	172	131	5	eee45759284baa3ed77da6a5fbcc4f8f6c553106
ToppCell	E16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	IDO1 TMEM158 CPE ECE1 FOXC1	1.55e-04	172	131	5	9a1743abcd5fbd38253ea84d88ad716cfb71de36
ToppCell	368C-Endothelial_cells-Endothelial-B_(Artery)-\|368C / Donor, Lineage, Cell class and subclass (all cells)	IDO1 ECE1 ADORA2A EFNB2 ANGPTL4	1.60e-04	173	131	5	ec88e871b49331fca59bc610a8ae58e2d5e76bc1
ToppCell	368C-Endothelial_cells-Endothelial-B_(Artery)\|368C / Donor, Lineage, Cell class and subclass (all cells)	IDO1 ECE1 ADORA2A EFNB2 ANGPTL4	1.60e-04	173	131	5	22200fe74e33e2beae0eed289ca8476bbc0b1b2d
ToppCell	10x5'-lymph-node_spleen-Hematopoietic_progenitors-Cycling_pre-Myeloid-2\|lymph-node_spleen / Manually curated celltypes from each tissue	PRUNE2 TYMP ASGR2 WDFY3 CDC20	1.60e-04	173	131	5	783b8fa08b9d8f597f251793eae164151662f1f9
ToppCell	PND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CPE DCAF12L2 TENM4 DMKN SYNE2	1.60e-04	173	131	5	30d67738633493d47f06ae452424382f069b6c0a
ToppCell	E18.5-Epithelial-Epithelial_Airway-Neurosecretory-PNEC-PNEC_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CELF6 TMEM158 CRTC1 VAT1L TRIM67	1.64e-04	174	131	5	742c73c9e090848b464323cb17579b86658c6792
ToppCell	normal_Lung-T/NK_cells-Exhausted_Tfh\|T/NK_cells / Location, Cell class and cell subclass	TYMP SEPHS2 KCNC3 CDC20 MAF	1.64e-04	174	131	5	e324320b52c904496e26fcecfa179b3431729ec0
ToppCell	E18.5-Epithelial-Epithelial_Airway-Neurosecretory-PNEC\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CELF6 TMEM158 CRTC1 VAT1L TRIM67	1.64e-04	174	131	5	7fed9722e64c60843092f2ba71256e3043011ef6
ToppCell	normal_Pleural_Fluid-Myeloid_cells-CD163+CD14+_DCs\|normal_Pleural_Fluid / Location, Cell class and cell subclass	TMEM158 IQCN FSIP2 LRRC27 WDFY3	1.73e-04	176	131	5	7a74217b7fa1032b918f00a3972dff5fab74671a
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 SYNE2 PKHD1 XYLB PDZD2	1.78e-04	177	131	5	2f81b26be89cc2fd8eafadaf7eae3c6ad6521462
ToppCell	facs-Marrow-B-cells-18m-Hematologic-hematopoietic_stem_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TTC24 TENT5C ERGIC1 CFD SLAMF7	1.78e-04	177	131	5	35d42b07d9c31528bf59199e361bb8a3bfbe3b75
ToppCell	facs-Lung-Endomucin-3m-Endothelial-Vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CPE ECE1 ALPK3 PPP1R16B FOXC1	1.82e-04	178	131	5	5cc182e6faa7ba5b88378d2c953be29bbbb95a7e
ToppCell	facs-Lung-Endomucin-3m-Endothelial-vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CPE ECE1 ALPK3 PPP1R16B FOXC1	1.82e-04	178	131	5	f9a16bc3f09c35c7d30e3809da024bc2dcf746ed
ToppCell	COVID-19-kidney-Epi_(Mes)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PRUNE2 GLIS3 TENM4 SYNE2 PKHD1	1.82e-04	178	131	5	544379f5a6145429762258d426b876bb36c112f5
ToppCell	T_cells-ISG-high_CD4+_T_cells\|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis	ECE1 ASGR2 PARP9 HERC5 MAF	1.87e-04	179	131	5	af35ef8a7768cee0c2af0590e5bec35cee6a4714
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 ACE2 XYLB SLC39A5 PDZD2	1.87e-04	179	131	5	d1ef7e1cb00336118e387b47f4f8120f53584391
ToppCell	COVID-19-Heart-EC_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	TM6SF1 EFNB2 SYNE2 PPP1R16B PDZD2	1.87e-04	179	131	5	2a53d94f6c30bf887dfe88f1693ea057218c852d
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 SYNE2 PPP1R16B XYLB PDZD2	1.92e-04	180	131	5	f8bdfd7bf7b3d52c659a29d8f5f80858e79da83e
ToppCell	droplet-Liver-LIVER-30m-Lymphocytic-B_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CPE VAT1L DCAF12L2 DMKN SCN10A	1.92e-04	180	131	5	3d95232b5785c705f41e01e3ffe0fa8dce1ff0a7
ToppCell	facs-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PRUNE2 TMEM158 CPE CFD EFNB2	1.92e-04	180	131	5	67c5068b660cd5e727a665cefe3bd5f8ae887221
ToppCell	droplet-Liver-LIVER-30m-Lymphocytic-B_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CPE VAT1L DCAF12L2 DMKN SCN10A	1.92e-04	180	131	5	47e345359064dc8ceec982b062e47802e728b43f
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 ACE2 SYNE2 XYLB PDZD2	1.97e-04	181	131	5	9542c19edc9bd2cba68c01c2a8407705398e3011
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CPE KCNC3 PKHD1 WDFY3 FOXC1	1.97e-04	181	131	5	071f9bb5d39070cdc473d9b0e094d196bc702b56
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 ACE2 SYNE2 XYLB PDZD2	1.97e-04	181	131	5	8f04f8cac5d705dc5f6cf6f4516d6e45b0aa4ae5
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Myeloid-Dendritic\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	FNIP2 ZNF787 FKBP15 TYMP KCNC3	2.02e-04	182	131	5	9a68d3bd1cc9139de9e9e711c249d47ade826bb1
ToppCell	facs-Lung-18m-Endothelial-arterial_endothelial\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PRUNE2 TMEM158 CPE EFNB2 FOXC1	2.02e-04	182	131	5	ebc812ed3f25839ea25f76b952c463d79a8325b1
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Myeloid-Dendritic-conventional_dendritic_cell\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	FNIP2 ZNF787 FKBP15 TYMP KCNC3	2.02e-04	182	131	5	d57d18732aa6fb7b2d430601568f9ba525ac6e3c
ToppCell	facs-Lung-Endomucin-3m-Endothelial-Artery_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 TMEM158 CPE ECE1 EFNB2	2.02e-04	182	131	5	aa113a0d2c1d28bda24cbb1221afd21b5628dc6d
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Myeloid-Dendritic-conventional_dendritic_cell-DC_c2-CD1C\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	FNIP2 ZNF787 FKBP15 TYMP KCNC3	2.02e-04	182	131	5	c3fb1460160744144aa31afc76c0a4d42ebdeb91
ToppCell	facs-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PRUNE2 TMEM158 CPE EFNB2 FOXC1	2.02e-04	182	131	5	47ff6b4002a4167412c79210651316d1342503f9
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 CPE PKHD1 WDFY3 FOXC1	2.07e-04	183	131	5	738e94b50c4c08c727d4eed0708dda08aa6891b4
ToppCell	COVID-19-B_cells-Plasma_cells\|COVID-19 / group, cell type (main and fine annotations)	TENT5C FBH1 CPEB4 SLAMF7 POLQ	2.07e-04	183	131	5	130c109f63a5e3c8f83cb96e32f4addf513b6415
ToppCell	COVID-19-B_cells\|COVID-19 / group, cell type (main and fine annotations)	TENT5C FBH1 CPEB4 SLAMF7 POLQ	2.07e-04	183	131	5	2c016bb59f131a0e821853b085289a3583f0a729
ToppCell	Control-Endothelial-Endothelial-Activated_Alv_Cap\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	KAT6A EFNB2 NUMB PARP9 HERC5	2.07e-04	183	131	5	e81c142770f44fd902b0631bc360c5b5339d4c75
ToppCell	droplet-Tongue-nan-24m-Epithelial-keratinocyte\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPTBN2 ACE2 EFNB2 DMKN MAF	2.07e-04	183	131	5	9e6c96ada930e8559246a270dfc69fb3cbb3bdf3
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 CPE PKHD1 WDFY3 FOXC1	2.07e-04	183	131	5	92fbd83a9d13ee91065cbd479fb298f1fd564568
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TMEM158 CPE ECE1 EFNB2 FOXC1	2.07e-04	183	131	5	fc9a7ba148c22d0c8a46f6bc56c772929ac496f7
ToppCell	Control-Myeloid-DC1\|Myeloid / Condition, Lineage and Cell class	TTC24 IDO1 FSIP2 CEP131 SLAMF7	2.13e-04	184	131	5	b5c1f57f0356969cfb0e1dac764684fc5583bc04
ToppCell	droplet-Marrow-nan-3m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATRX KAT6A APC MEF2A UVRAG	2.13e-04	184	131	5	1154a5ad7b8512272b7476f949ddac350910bfb7
ToppCell	COVID-19-kidney-PCT-S1/S2\|kidney / Disease (COVID-19 only), tissue and cell type	PRUNE2 ACE2 XYLB PDZD2 MAF	2.13e-04	184	131	5	dc71f22583fc54b89b242cbb602f4bbe86f576ec
ToppCell	Endothelial-E\|World / shred on cell class and cell subclass (v4)	TMEM158 CPE ECE1 EFNB2 FOXC1	2.13e-04	184	131	5	b4c561924c508536fd2112e91e32176b95fdf63a
ToppCell	facs-Heart-LA-18m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTX4 TMEM158 CPE ECE1 FOXC1	2.18e-04	185	131	5	1ecfca049c0c1110fd1b2256db7cb7abda6afb04
Drug	Lincomycin hydrochloride [859-18-7]; Up 200; 9uM; HL60; HT_HG-U133A	UBR4 SUN1 CRTC1 TEX15 MMP24 EFNB2 XYLB SLAMF7 FOXC1	2.02e-06	197	130	9	2380_UP
Drug	Bepridil hydrochloride [74764-40-2]; Up 200; 10uM; MCF7; HT_HG-U133A	GPR37 ASAP3 TENT5C ADORA2A KMT2D CEP250 XYLB HERC5	1.38e-05	190	130	8	5674_UP
Drug	Nitrofurantoin [67-20-9]; Down 200; 16.8uM; PC3; HT_HG-U133A	CA11 SPTBN2 KAT6A APC TM6SF1 ALPK3 NADK FOXC1	1.61e-05	194	130	8	3674_DN
Drug	Tolmetin sodium salt dihydrate [64490-92-2]; Down 200; 12.6uM; MCF7; HT_HG-U133A	ATRX KAT6A ASAP3 EML2 CRTC1 CEP250 SCN10A NADK	1.67e-05	195	130	8	4167_DN
Drug	Tinidazole [19387-91-8]; Up 200; 16.2uM; MCF7; HT_HG-U133A	SUN1 APC SCN10A XYLB WDFY3 HERC5 FOXC1 MAF	1.73e-05	196	130	8	3896_UP
Drug	Xamoterol hemifumarate [73210-73-8]; Down 200; 5uM; MCF7; HT_HG-U133A	TMEM158 SPTBN2 ASAP3 APC CRTC1 SCN10A WDFY3 HERC5	1.80e-05	197	130	8	3401_DN
Drug	Naringin hydrate [11032-30-7]; Up 200; 6.6uM; MCF7; HT_HG-U133A	MARCHF6 ASAP3 APC TENT5C CRTC1 TYRP1 NADK NOVA1	1.86e-05	198	130	8	3286_UP
Drug	Scopoletin [92-61-5]; Down 200; 20.8uM; HL60; HT_HG-U133A	UBR4 EML2 TYMP MEF2A MLH3 SCN10A NADK WDFY3	1.86e-05	198	130	8	3131_DN
Drug	Clebopride maleate [84370-95-6]; Down 200; 8.2uM; PC3; HT_HG-U133A	ATRX GPR37 ASAP3 APC ECE1 NADK PCSK7 C5	1.93e-05	199	130	8	6311_DN
Disease	Bardet-Biedl syndrome (implicated_via_orthology)	BBS2 BBS7 CEP131	1.28e-05	11	128	3	DOID:1935 (implicated_via_orthology)
Disease	MITOCHONDRIAL DNA DEPLETION SYNDROME 5 (ENCEPHALOMYOPATHIC WITH OR WITHOUT METHYLMALONIC ACIDURIA)	TYMP SUCLA2	1.87e-05	2	128	2	C2749864
Disease	Colorectal Carcinoma	IRS4 SPTBN2 ASAP3 APC EML2 CPE TYMP MLH3 DMKN PKHD1 MAF	2.51e-04	702	128	11	C0009402
Disease	stearoyl sphingomyelin (d18:1/18:0) measurement	SYNE2 ANGPTL4	2.77e-04	6	128	2	EFO_0800611
Disease	Obesity	IDO1 BBS2 CPE SUCLA2 BBS7 ANGPTL4	2.81e-04	205	128	6	C0028754
Disease	intellectual disability (implicated_via_orthology)	IRS4 ATRX UBR4 MEF2A	3.24e-04	75	128	4	DOID:1059 (implicated_via_orthology)
Disease	electrocardiography, PR interval	SCN10A XYLB	3.87e-04	7	128	2	EFO_0004327, EFO_0004462
Disease	Lynch Syndrome	APC MLH3	6.59e-04	9	128	2	C4552100
Disease	breast cancer	ECE1 CEP131	6.59e-04	9	128	2	MONDO_0007254
Disease	level of Sphingomyelin (d34:0) in blood serum	PELP1 SYNE2	1.00e-03	11	128	2	OBA_2045176
Disease	household income, smoking status measurement, educational attainment, protein intake measurement, carbohydrate intake measurement, alcohol consumption measurement, physical activity measurement, body mass index, energy intake measurement	ZNF787 EFNB2	1.00e-03	11	128	2	EFO_0004340, EFO_0006527, EFO_0007878, EFO_0008002, EFO_0009374, EFO_0009695, EFO_0010810, EFO_0010811, EFO_0011015
Disease	triglyceride measurement, high density lipoprotein cholesterol measurement	MYO1H TENM4 RP1L1 ANGPTL4 PCSK7 UVRAG	1.28e-03	274	128	6	EFO_0004530, EFO_0004612
Disease	Ciliopathies	BBS2 BBS7 PKHD1 INVS	1.37e-03	110	128	4	C4277690
Disease	esophageal adenocarcinoma, Barrett's esophagus, sex interaction measurement	CRTC1 RP1L1	1.41e-03	13	128	2	EFO_0000280, EFO_0000478, EFO_0008343
Disease	Bardet-Biedl syndrome (is_implicated_in)	BBS2 BBS7	1.64e-03	14	128	2	DOID:1935 (is_implicated_in)
Disease	cutaneous melanoma	GPR37 ADD3 TYRP1 SYNE2	1.94e-03	121	128	4	EFO_0000389
Disease	Tetralogy of Fallot	NKX2-6 FOXC1	2.15e-03	16	128	2	C0039685
Disease	household income, smoking status measurement, educational attainment, protein intake measurement, carbohydrate intake measurement, alcohol consumption measurement, body mass index, energy intake measurement	ZNF787 EFNB2	2.15e-03	16	128	2	EFO_0004340, EFO_0006527, EFO_0007878, EFO_0009374, EFO_0009695, EFO_0010810, EFO_0010811, EFO_0011015
Disease	Disorder of eye	BBS2 TYRP1 BBS7 FOXC1 INVS	2.36e-03	212	128	5	C0015397
Disease	Bardet-Biedl syndrome 1 (disorder)	BBS2 BBS7	2.43e-03	17	128	2	C2936862
Disease	Antibody Deficiency Syndrome	CFD C5	2.43e-03	17	128	2	C0003257
Disease	cutaneous melanoma, hair color	ADD3 TYRP1 SYNE2	2.50e-03	62	128	3	EFO_0000389, EFO_0003924
Disease	Child Behaviour Checklist assessment	NKX2-6 TENM4	2.73e-03	18	128	2	EFO_0005661
Disease	Bardet-Biedl syndrome	BBS2 BBS7	2.73e-03	18	128	2	cv:C0752166
Disease	cortical thickness	FNIP2 IRF2BP2 SPTBN2 GLIS3 EML2 ECE1 TM6SF1 NHSL1 EFNB2 CPEB4 PKHD1 PDZD2	3.36e-03	1113	128	12	EFO_0004840
Disease	transitional cell carcinoma (is_implicated_in)	APC TYMP	4.07e-03	22	128	2	DOID:2671 (is_implicated_in)
Disease	triglycerides:total lipids ratio, low density lipoprotein cholesterol measurement	ASGR2 SYNE2 ANGPTL4 PCSK7	4.20e-03	150	128	4	EFO_0004611, EFO_0020947

Protein segments in the cluster

Peptide	Gene	Start	Entry
TVLALHNGNGGDSGE	BBS7	191	Q8IWZ6
GRHLASGGNDNLVNV	CDC20	321	Q12834
AAAANAVAHGLNGGS	CDX2	86	Q99626
NGGHLDAKAADGNTA	ASAP3	611	Q8TDY4
DGNAELLQFSVHLGG	ANGPTL4	281	Q9BY76
AHGSDGEQVSLRLNG	ADORA2A	326	P29274
TDFGLGDAHQSDGLN	ADGB	586	Q8N7X0
VQALAGAGGVDNLHV	ADD3	321	Q9UEY8
SEGHGGAQLQAELRS	ASGR2	81	P07307
SGLHFGLVNISGNNE	AGTR2	16	P50052
QHSGLGLINSFASGE	ALPK3	461	Q96L96
LFGARDGAGSEHQIN	CA11	136	O75493
KQIGANAHGAGSRSL	DOT1L	916	Q8TEK3
LDAFDGHAARALNQG	CDIPT	46	O14735
FGSQGEAQAAIRGLH	CELF6	181	Q96J87
DASHLLNQSGGAGED	RBM27	761	Q9P2N5
GGQNATPQGHLAATL	NKX2-6	281	A6NCS4
EAQLNGGHSAEESLG	RAD17	616	O75943
GASNILGLEASGHVA	TP53I3	56	Q53FA7
GNQGNAAGRLATVHE	IQCN	11	Q9H0B3
VNAANEDLLHGGGLA	PARP9	136	Q8IXQ6
AHLSGAAFQGLEGTL	LRRC3C	116	A6NJW4
ASVQLNGAHLCGGVL	CFD	41	P00746
LGNANHDGNDLFLVA	MMP24	266	Q9Y5R2
LLGIQQTAGGGHAAQ	IDO1	276	P14902
ALISNSHQLQGGFDG	MAF	116	O75444
QQLAAAAGAGAGASL	MAF	136	O75444
AGLAQAHQGCGIHAI	DCAF12L2	141	Q5VW00
FANGHLEILGAINDG	FSIP2	1596	Q5CZC0
QADENLGHLGGASGT	NHSL1	366	Q5SYE7
NSAGHSGNNILGSEV	EFNB2	211	P52799
HNGLGENGSQAAGLD	NADK	256	O95544
SIFVVASGNGGQHND	PCSK7	321	Q16549
SEGNGFGSLAALVVH	FAT2	231	Q9NYQ8
NGEAGGNLLVLVDQH	MLH3	1211	Q9UHC1
LLSVNGASLAGLAHG	PDZD2	2671	O15018
DQLVAGGQLGELHNG	PCED1A	76	Q9H1Q7
VQNIHGAFNALGGAD	ERGIC1	161	Q969X5
LASLFGLDQAAAGHG	FKBP15	21	Q5T1M5
GEGLHAAHQAILQQG	MARCHF6	601	O60337
SNLGIIAHAGQGVSQ	LHX4	336	Q969G2
HLGQAALSSLVAGGQ	MEF2A	371	Q02078
HGSVGGAQNLSALGA	PELP1	76	Q8IZL8
QTSQHNSGLGAERGA	IQSEC3	1046	Q9UPP2
GGAISTAQAQAFLGH	POU2F1	36	P14859
AGVQVHQLLAGSGGA	HERC5	71	Q9UII4
NHGGIASESLAGGLV	NCOA6	1936	Q14686
DAQGATLLHIAGANG	PPP1R16B	226	Q96T49
GGSAASGFHQQLRLA	KAT6A	136	Q92794
LDHLTGVGNNSEGGR	ATRX	1851	P46100
TLVGGNHQSGIRGDA	FBH1	726	Q8NFZ0
GRALAQNGSLGEGIH	GPR37	216	O15354
AIIGGNCALQGFNHE	BBS2	136	Q9BXC9
GNRVGEAAHALGNTG	DMKN	96	Q6E0U4
LAANLTHLGIGGAGQ	CRTC1	281	Q6UUV9
NQAGGDLGHLASAAA	FOXC1	476	Q12948
AADIAGQLSHAADLG	FNIP2	806	Q9P278
SQGIQSLGLNAGSEH	POLQ	2026	O75417
AGGGLNNANVFHLAG	C5	636	P01031
SLSNHGSQNGLDLGD	GLIS3	81	Q8NEA6
GDNIAQGSGHENSLE	CEP250	356	Q9BV73
LEASRHLGGEQSQAG	REXO1L1P	26	Q8IX06
FVLSANLHGGDLVAN	CPE	241	P16870
LLRNGANEGFHEAVG	ACE2	391	Q9BYF1
ANNHLESQGVRGTAG	GPR142	91	Q7Z601
HQGGVPAASANNGAL	CPEB4	191	Q17RY0
LVLAEGAHSDAGSQG	DVL1	81	O14640
GGNRITQAVLGAHDG	EML2	281	O95834
GRHTLGENIADNGGL	ECE1	661	P42892
HADGGVAAGVAVLDN	GSS	456	P48637
QGSEHLLNGQAFSGE	CA10	141	Q9NS85
AHGGNDVSNAIGPLV	SLC20A2	501	Q08357
VGDSLHNFADGLAIG	SLC39A12	546	Q504Y0
GTAHQALKANNTGGG	CEP131	386	Q9UPN4
AALILVADNAGGSHA	IRF2BP2	426	Q7Z5L9
VLQAALHGQSSIGNG	JADE3	641	Q92613
SNNLAADAVGHGGVI	PRDM4	241	Q9UKN5
LANAALAGGFVQGAN	PTX4	456	Q96A99
EGHENAAVQGAGAAA	FAM114A1	51	Q8IWE2
SQVHAAAVNGDKGAL	INVS	16	Q9Y283
TAAAAAGLLGHANLA	NOVA1	281	P51513
AGLLGHANLAGVAAF	NOVA1	286	P51513
LARGDNQAGGAAAAA	IRS4	1196	O14654
QHLNGSAAFNGVDDG	NUMB	581	P49757
AEFSDLNLVAHANGG	SYN1	146	P17600
EDLVGSLNGGHANVH	UVRAG	566	Q9P2Y5
DILHGNFQEGGQLAS	PRUNE2	2051	Q8WUY3
GLGDNGATQHEAEAL	SYNE2	4301	Q8WXH0
QSAIATGHQAAGIGN	FNBP4	816	Q8N3X1
TGHQAAGIGNQATGI	FNBP4	821	Q8N3X1
GLELSGDHASNQGAV	LRRC27	201	Q9C0I9
GLQHLVSGAEDQNGG	RFFL	291	Q8WZ73
VAHLLQGGNLHGQAE	LARS1	606	Q9P2J5
KNASNDIVRHGGSLG	PSMD1	466	Q99460
TAIAHLFADNGNLGI	SIAH2	301	O43255
GGIHAAASHGVLLND	PKHD1	3026	P08F94
NIALNSHLAATGGGI	METTL22	246	Q9BUU2
AAAGGAHQNSAVAAA	SOX1	286	O00570
VLGSSGLFNNHGLQV	SUCLA2	31	Q9P2R7
DGLHNLTDGLAIGAA	SLC39A5	391	Q6ZMH5
LNGSAAGHVLVKDNG	TENT5C	71	Q5VWP2
QNAEGLTALHSAAGG	ANKDD1A	221	Q495B1
HGNDKDSVLLGNSRG	APC	361	P25054
DENGHVGGLNLLAAG	SLC25A12	511	O75746
GRVAATSLGNLTNHG	SAV1	181	Q9H4B6
GNGLHNGFLTASSLD	ZNF532	86	Q9HCE3
GLQAGAAAAASLEHD	TRIM67	56	Q6ZTA4
DITGFGILGHSQNLA	SEPHS2	316	Q99611
LHNLAHLFLNGTGGQ	TYRP1	376	P17643
RAGHGALQAGQNHEA	TTC24	41	A2A3L6
NSAGHLNGSARTIGA	WDFY3	1371	Q8IZQ1
VDSANALANGLIAGG	SPTBN2	1751	O15020
ALANGLIAGGHAARA	SPTBN2	1756	O15020
QGSGHEDNLQGEAAA	RP1L1	1806	Q8IWN7
DAVVIGAGHNGLVAA	PYROXD2	36	Q8N2H3
HIAANTARGSSGGLQ	SCN10A	961	Q9Y5Y9
IEHLGLAAGGAQQDL	TMEM158	126	Q8WZ71
FSQVLALSGAGQQHG	XYLB	86	O75191
HGNSGLLATKSNENG	TENM4	1676	Q6N022
ALGQAANESHNGSIL	SLAMF7	166	Q9NQ25
VHSAGGGVGQAVAQL	VAT1L	186	Q9HCJ6
NQNGNIHGEEGLFSL	TRIM49D1	366	C9J1S8
LLGGADLAQGNHSGA	TTC23	361	Q5W5X9
IQGNGDVGAAAATAH	SUN1	166	O94901
GASGHITLNVNQGAE	TEX15	2596	Q9BXT5
SAGQGAGHLQLHNAA	UBR4	1546	Q5T4S7
NHNGNLLVTGAADGV	WDR91	571	A4D1P6
LSGHAGTQAQGAARV	TYMP	316	P19971
QNLSGAAAGEALVGA	XYLT2	121	Q9H1B5
GAGLHNLGNTCFLNA	USP36	121	Q9P275
LATATANGHGLKGND	USP36	586	Q9P275
ANGHGLKGNDESAGL	USP36	591	Q9P275
HAGGLAQAQFSHIGA	TM6SF1	301	Q9BZW5
LAHQRAQHGDGLGAA	ZNF787	296	Q6DD87
ANAANAAGAHDGGLD	KCNC3	211	Q14003
QNHVAAGSGQERSAG	KMT2D	3471	O14686
LNNHFILISGESGAG	MYO1H	96	Q8N1T3