Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	structural constituent of cytoskeleton	KRT6A KRT6B KRT14 KRT16 PLS1	7.79e-07	130	27	5	GO:0005200
GeneOntologyMolecularFunction	structural constituent of skin epidermis	KRT6A KRT6B KRT6C	2.62e-05	43	27	3	GO:0030280
GeneOntologyMolecularFunction	structural molecule activity	KRT6A KRT6B KRT14 KRT16 KRT6C PLS1 NUP54	1.39e-04	891	27	7	GO:0005198
GeneOntologyBiologicalProcess	intermediate filament organization	KRT6A KRT6B KRT14 KRT16 KRT6C	4.21e-08	75	27	5	GO:0045109
GeneOntologyBiologicalProcess	intermediate filament cytoskeleton organization	KRT6A KRT6B KRT14 KRT16 KRT6C	1.71e-07	99	27	5	GO:0045104
GeneOntologyBiologicalProcess	intermediate filament-based process	KRT6A KRT6B KRT14 KRT16 KRT6C	1.80e-07	100	27	5	GO:0045103
GeneOntologyBiologicalProcess	epidermal cell differentiation	KRT6A KRT6B KRT14 KRT16 KRT6C PLS1	1.50e-06	284	27	6	GO:0009913
GeneOntologyBiologicalProcess	keratinocyte differentiation	KRT6A KRT6B KRT14 KRT16 KRT6C	4.20e-06	189	27	5	GO:0030216
GeneOntologyBiologicalProcess	keratinization	KRT6A KRT6B KRT16 KRT6C	4.81e-06	87	27	4	GO:0031424
GeneOntologyBiologicalProcess	epidermis development	KRT6A KRT6B KRT14 KRT16 KRT6C PLS1	2.40e-05	461	27	6	GO:0008544
GeneOntologyBiologicalProcess	homophilic cell adhesion via plasma membrane adhesion molecules	PCDHGB6 DSG1 PCDHGA11 CDH8	9.75e-05	187	27	4	GO:0007156
GeneOntologyBiologicalProcess	epithelial cell differentiation	KLF15 KRT6A KRT6B KRT14 KRT16 KRT6C PLS1	9.81e-05	870	27	7	GO:0030855
GeneOntologyBiologicalProcess	skin development	KRT6A KRT6B KRT14 KRT16 KRT6C	1.10e-04	373	27	5	GO:0043588
GeneOntologyBiologicalProcess	cell-cell adhesion via plasma-membrane adhesion molecules	PCDHGB6 DSG1 PCDHGA11 CDH8	6.93e-04	313	27	4	GO:0098742
GeneOntologyCellularComponent	keratin filament	KRT6A KRT6B KRT14 KRT16 KRT6C	1.44e-07	97	27	5	GO:0045095
GeneOntologyCellularComponent	intermediate filament	KRT6A KRT6B KRT14 KRT16 KRT6C	9.60e-06	227	27	5	GO:0005882
GeneOntologyCellularComponent	intermediate filament cytoskeleton	KRT6A KRT6B KRT14 KRT16 KRT6C	1.95e-05	263	27	5	GO:0045111
GeneOntologyCellularComponent	cornified envelope	KRT14 KRT16 DSG1	9.51e-05	69	27	3	GO:0001533
GeneOntologyCellularComponent	polymeric cytoskeletal fiber	KRT6A KRT6B KRT14 KRT16 KRT6C PLS1	8.47e-04	899	27	6	GO:0099513
GeneOntologyCellularComponent	supramolecular fiber	KRT6A KRT6B KRT14 KRT16 KRT6C PLS1	3.38e-03	1179	27	6	GO:0099512
GeneOntologyCellularComponent	supramolecular polymer	KRT6A KRT6B KRT14 KRT16 KRT6C PLS1	3.50e-03	1187	27	6	GO:0099081
GeneOntologyCellularComponent	stereocilium	PKHD1L1 PLS1	3.57e-03	69	27	2	GO:0032420
GeneOntologyCellularComponent	stereocilium bundle	PKHD1L1 PLS1	4.66e-03	79	27	2	GO:0032421
HumanPheno	Palmoplantar blistering	KRT6A KRT6B KRT14 KRT16 DSG1	4.06e-12	11	10	5	HP:0007446
HumanPheno	Blistering by anatomical location	KRT6A KRT6B KRT14 KRT16 DSG1	5.71e-10	26	10	5	HP:0033800
HumanPheno	Palmoplantar keratoderma	KRT6A KRT6B KRT14 KRT16 KRT6C DSG1	2.15e-08	114	10	6	HP:0000982
HumanPheno	Eruptive vellus hair cyst	KRT6A KRT6B KRT16	2.18e-08	4	10	3	HP:0025248
HumanPheno	Steatocystoma multiplex	KRT6A KRT6B KRT16	2.18e-08	4	10	3	HP:0012035
HumanPheno	Palmoplantar hyperkeratosis	KRT6A KRT6B KRT14 KRT16 KRT6C DSG1	4.54e-08	129	10	6	HP:0000972
HumanPheno	Palmar hyperkeratosis	KRT6A KRT6B KRT14 KRT16 KRT6C DSG1	4.98e-08	131	10	6	HP:0010765
HumanPheno	Plantar hyperkeratosis	KRT6A KRT6B KRT14 KRT16 KRT6C DSG1	5.22e-08	132	10	6	HP:0007556
HumanPheno	Linear arrays of macular hyperkeratoses in flexural areas	KRT6A KRT6B KRT16	5.44e-08	5	10	3	HP:0007490
HumanPheno	Hyperplastic callus formation	KRT6A KRT6B KRT16	5.44e-08	5	10	3	HP:0030268
HumanPheno	White lesion of the oral mucosa	KRT6A KRT6B KRT16 KRT6C	1.50e-07	28	10	4	HP:0025125
HumanPheno	Oral leukoplakia	KRT6A KRT6B KRT16 KRT6C	1.50e-07	28	10	4	HP:0002745
HumanPheno	Onychogryposis	KRT6A KRT6B KRT14 KRT16	1.74e-07	29	10	4	HP:0001805
HumanPheno	Onychogryposis of toenails	KRT6A KRT6B KRT16	1.90e-07	7	10	3	HP:0008401
HumanPheno	Onychogryposis	KRT6A KRT6B KRT16	1.90e-07	7	10	3	HP:0001819
HumanPheno	Abnormality of the plantar skin of foot	KRT6A KRT6B KRT14 KRT16 KRT6C DSG1	2.46e-07	171	10	6	HP:0100872
HumanPheno	Onychogryposis of fingernail	KRT6A KRT6B KRT16	4.55e-07	9	10	3	HP:0040036
HumanPheno	Lower limb pain	KRT6A KRT6B KRT14 KRT16	7.33e-07	41	10	4	HP:0012514
HumanPheno	Angular cheilitis	KRT6A KRT6B KRT16	1.19e-06	12	10	3	HP:0030318
HumanPheno	Abnormal blistering of the skin	KRT6A KRT6B KRT14 KRT16 DSG1	1.24e-06	115	10	5	HP:0008066
HumanPheno	Hyperkeratosis	KRT6A KRT6B KRT14 KRT16 KRT6C DSG1	1.55e-06	233	10	6	HP:0000962
HumanPheno	Palmoplantar hyperhidrosis	KRT6A KRT6B KRT16	1.96e-06	14	10	3	HP:0007410
HumanPheno	Abnormality of keratinization	KRT6A KRT6B KRT14 KRT16 KRT6C DSG1	2.03e-06	244	10	6	HP:0001035
HumanPheno	Ear pain	KRT6A KRT6B KRT16	2.45e-06	15	10	3	HP:0030766
HumanPheno	Limb pain	KRT6A KRT6B KRT14 KRT16	2.82e-06	57	10	4	HP:0009763
HumanPheno	Fingernail dysplasia	KRT6A KRT6B KRT16	3.01e-06	16	10	3	HP:0100798
HumanPheno	Palmar hyperhidrosis	KRT6A KRT6B KRT16	3.01e-06	16	10	3	HP:0006089
HumanPheno	Paronychia	KRT6A KRT6B KRT16	3.01e-06	16	10	3	HP:0001818
HumanPheno	Nail dystrophy	KRT6A KRT6B KRT14 KRT16 DSG1	5.63e-06	156	10	5	HP:0008404
HumanPheno	Hyperhidrosis	KRT6A KRT6B KRT14 KRT16 DSG1	7.87e-06	167	10	5	HP:0000975
HumanPheno	Abnormality of the periungual region	KRT6A KRT6B KRT16	8.23e-06	22	10	3	HP:0100803
HumanPheno	Supernumerary tooth	KRT6A KRT6B KRT14 KRT16	1.41e-05	85	10	4	HP:0011069
HumanPheno	Follicular hyperkeratosis	KRT6A KRT6B KRT16	2.15e-05	30	10	3	HP:0007502
HumanPheno	Epidermal thickening	KRT6A KRT6B KRT14 KRT16 KRT6C DSG1	2.65e-05	379	10	6	HP:0011368
HumanPheno	Hypohidrosis or hyperhidrosis	KRT6A KRT6B KRT14 KRT16 DSG1	4.17e-05	235	10	5	HP:0007550
HumanPheno	Abnormal skin morphology of the palm	KRT6A KRT6B KRT14 KRT16 KRT6C DSG1	4.34e-05	413	10	6	HP:0040211
HumanPheno	Natal tooth	KRT6A KRT6B KRT16	4.43e-05	38	10	3	HP:0000695
HumanPheno	Pain in head and neck region	KRT6A KRT6B KRT16	5.18e-05	40	10	3	HP:0046506
HumanPheno	Abnormality of skin adnexa physiology	KRT6A KRT6B KRT14 KRT16 DSG1	5.52e-05	249	10	5	HP:0025276
HumanPheno	Thickened skin	KRT6A KRT6B KRT14 KRT16 KRT6C DSG1	5.55e-05	431	10	6	HP:0001072
HumanPheno	Abnormal sweat gland morphology	KRT6A KRT6B KRT14 KRT16 DSG1	6.80e-05	260	10	5	HP:0000971
HumanPheno	Nail dysplasia	KRT6A KRT6B KRT14 KRT16 DSG1	7.32e-05	264	10	5	HP:0002164
HumanPheno	Epidermoid cyst	KRT6A KRT6B KRT16	7.41e-05	45	10	3	HP:0200040
HumanPheno	Advanced eruption of teeth	KRT6A KRT6B KRT16	7.91e-05	46	10	3	HP:0006288
HumanPheno	Cutaneous cyst	KRT6A KRT6B KRT16	1.08e-04	51	10	3	HP:0025245
HumanPheno	Epidermal acanthosis	KRT16 KRT6C DSG1	1.28e-04	54	10	3	HP:0025092
HumanPheno	Cheilitis	KRT6A KRT6B KRT16	1.59e-04	58	10	3	HP:0100825
HumanPheno	Abnormal palm morphology	KRT6A KRT6B KRT14 KRT16 KRT6C DSG1	1.63e-04	521	10	6	HP:0100871
HumanPheno	Hoarse voice	KRT6A KRT6B KRT14 KRT16	1.66e-04	159	10	4	HP:0001609
HumanPheno	Regional abnormality of skin	KRT6A KRT6B KRT14 KRT16 KRT6C DSG1	2.02e-04	541	10	6	HP:0011356
HumanPheno	Abnormal oral mucosa morphology	KRT6A KRT6B KRT14 KRT16 KRT6C	4.19e-04	381	10	5	HP:0011830
HumanPheno	Abnormal epidermal morphology	KRT16 KRT6C DSG1	6.65e-04	94	10	3	HP:0011124
HumanPheno	Abnormal number of teeth	KRT6A KRT6B KRT14 KRT16 CNOT1	6.69e-04	421	10	5	HP:0006483
HumanPheno	Abnormal fingernail morphology	KRT6A KRT6B KRT14 KRT16	6.86e-04	230	10	4	HP:0001231
HumanPheno	Onycholysis	KRT14 DSG1	7.14e-04	21	10	2	HP:0001806
HumanPheno	Hypergranulosis	KRT16 DSG1	7.85e-04	22	10	2	HP:0025114
HumanPheno	Congenital nystagmus	KRT14 NUP54	7.85e-04	22	10	2	HP:0006934
HumanPheno	Abnormal nail attachment	KRT14 DSG1	9.36e-04	24	10	2	HP:0025756
HumanPheno	Alopecia	KRT6A KRT6B KRT14 KRT16	1.11e-03	261	10	4	HP:0001596
HumanPheno	Abnormal nail morphology	KRT6A KRT6B KRT14 KRT16 DSG1	1.71e-03	516	10	5	HP:0001597
HumanPheno	Sparse or absent hair	KRT6A KRT6B KRT14 KRT16 DSG1	1.85e-03	525	10	5	HP:0002115
HumanPheno	Neoplasm of the skin	KRT6A KRT6B KRT14 KRT16	3.89e-03	366	10	4	HP:0008069
MousePheno	abnormal filiform papillae morphology	KRT6A KRT6B KRT16	1.18e-07	7	22	3	MP:0000763
MousePheno	abnormal tongue epithelium morphology	KRT6A KRT6B KRT16	9.66e-06	27	22	3	MP:0000764
MousePheno	abnormal keratinocyte morphology	KRT6A KRT6B KRT14	7.97e-05	54	22	3	MP:0002655
MousePheno	abnormal esophagus morphology	KRT6A KRT6B KRT14	1.45e-04	66	22	3	MP:0000467
MousePheno	abnormal digestive system morphology	MUC19 KRT6A MLLT6 KRT6B KRT14 KRT16 PLS1 FDX2	3.71e-04	1233	22	8	MP:0000462
Domain	Intermediate_filament_CS	KRT6A KRT6B KRT14 KRT16 KRT6C	2.83e-08	63	27	5	IPR018039
Domain	Filament	KRT6A KRT6B KRT14 KRT16 KRT6C	5.20e-08	71	27	5	SM01391
Domain	IF	KRT6A KRT6B KRT14 KRT16 KRT6C	5.59e-08	72	27	5	PS00226
Domain	Filament	KRT6A KRT6B KRT14 KRT16 KRT6C	5.99e-08	73	27	5	PF00038
Domain	IF	KRT6A KRT6B KRT14 KRT16 KRT6C	7.35e-08	76	27	5	IPR001664
Domain	Keratin_2_head	KRT6A KRT6B KRT6C	5.34e-06	24	27	3	IPR032444
Domain	Keratin_2_head	KRT6A KRT6B KRT6C	5.34e-06	24	27	3	PF16208
Domain	Keratin_II	KRT6A KRT6B KRT6C	6.85e-06	26	27	3	IPR003054
Domain	Cadherin_CS	PCDHGB6 DSG1 PCDHGA11 CDH8	1.74e-05	109	27	4	IPR020894
Domain	Cadherin	PCDHGB6 DSG1 PCDHGA11 CDH8	2.00e-05	113	27	4	PF00028
Domain	CADHERIN_1	PCDHGB6 DSG1 PCDHGA11 CDH8	2.00e-05	113	27	4	PS00232
Domain	-	PCDHGB6 DSG1 PCDHGA11 CDH8	2.07e-05	114	27	4	2.60.40.60
Domain	CADHERIN_2	PCDHGB6 DSG1 PCDHGA11 CDH8	2.07e-05	114	27	4	PS50268
Domain	CA	PCDHGB6 DSG1 PCDHGA11 CDH8	2.15e-05	115	27	4	SM00112
Domain	Cadherin-like	PCDHGB6 DSG1 PCDHGA11 CDH8	2.22e-05	116	27	4	IPR015919
Domain	Cadherin	PCDHGB6 DSG1 PCDHGA11 CDH8	2.37e-05	118	27	4	IPR002126
Domain	Cadherin_C	DSG1 CDH8	5.92e-04	25	27	2	PF01049
Domain	Cadherin_cytoplasmic-dom	DSG1 CDH8	5.92e-04	25	27	2	IPR000233
Domain	Catenin_binding_dom	DSG1 CDH8	7.98e-04	29	27	2	IPR027397
Domain	-	DSG1 CDH8	7.98e-04	29	27	2	4.10.900.10
Domain	Cadherin_tail	PCDHGB6 PCDHGA11	1.30e-03	37	27	2	PF15974
Domain	Cadherin_CBD	PCDHGB6 PCDHGA11	1.30e-03	37	27	2	IPR031904
Domain	Cadherin_C_2	PCDHGB6 PCDHGA11	1.67e-03	42	27	2	PF16492
Domain	Cadherin_C	PCDHGB6 PCDHGA11	1.67e-03	42	27	2	IPR032455
Domain	Keratin_I	KRT14 KRT16	1.83e-03	44	27	2	IPR002957
Domain	Cadherin_N	PCDHGB6 PCDHGA11	3.96e-03	65	27	2	IPR013164
Domain	Cadherin_2	PCDHGB6 PCDHGA11	3.96e-03	65	27	2	PF08266
Pathway	REACTOME_FORMATION_OF_THE_CORNIFIED_ENVELOPE	KRT6A KRT6B KRT14 KRT16 KRT6C DSG1	8.86e-09	129	18	6	M27649
Pathway	REACTOME_FORMATION_OF_THE_CORNIFIED_ENVELOPE	KRT6A KRT6B KRT14 KRT16 DSG1	6.41e-08	87	18	5	MM15351
Pathway	REACTOME_KERATINIZATION	KRT6A KRT6B KRT14 KRT16 KRT6C DSG1	1.98e-07	217	18	6	M27640
Pathway	REACTOME_KERATINIZATION	KRT6A KRT6B KRT14 KRT16 DSG1	1.08e-06	153	18	5	MM15343
Pathway	REACTOME_DEVELOPMENTAL_BIOLOGY	KRT6A KRT6B KRT14 KRT16 DSG1	3.27e-04	502	18	5	MM14537
Pathway	REACTOME_DEVELOPMENTAL_BIOLOGY	KRT6A KRT6B KRT14 KRT16 KRT6C DSG1 CNOT1	1.28e-03	1432	18	7	M509
Pubmed	Pachyonychia Congenita	KRT6A KRT6B KRT16 KRT6C	1.44e-12	5	27	4	20301457
Pubmed	Suppression of DDX39B sensitizes ovarian cancer cells to DNA-damaging chemotherapeutic agents via destabilizing BRCA1 mRNA.	KRT6A KRT6B KRT14 KRT16 KRT6C DSG1	2.07e-10	107	27	6	32989256
Pubmed	Activated Braf induces esophageal dilation and gastric epithelial hyperplasia in mice.	KRT6A KRT6B KRT14 KRT16 DSG1	2.28e-10	45	27	5	28973166
Pubmed	Cloning and characterization of multiple human genes and cDNAs encoding highly related type II keratin 6 isoforms.	KRT6A KRT6B KRT6C	4.17e-10	3	27	3	7543104
Pubmed	Genetic variants in pachyonychia congenita-associated keratins increase susceptibility to tooth decay.	KRT6A KRT6B KRT6C	4.17e-10	3	27	3	29357356
Pubmed	A role for keratins in supporting mitochondrial organization and function in skin keratinocytes.	KRT6A KRT6B KRT16	4.17e-10	3	27	3	32213122
Pubmed	Loss of keratin 6 (K6) proteins reveals a function for intermediate filaments during wound repair.	KRT6A KRT6B KRT14	4.17e-10	3	27	3	14568992
Pubmed	New consensus nomenclature for mammalian keratins.	KRT6A KRT6B KRT14 KRT16 KRT6C	1.30e-09	63	27	5	16831889
Pubmed	A review of the clinical phenotype of 254 patients with genetically confirmed pachyonychia congenita.	KRT6A KRT6B KRT16	1.67e-09	4	27	3	22264670
Pubmed	Mouse models in preclinical studies for pachyonychia congenita.	KRT6A KRT6B KRT16	1.67e-09	4	27	3	16250208
Pubmed	Nuclear control of lung cancer cells migration, invasion and bioenergetics by eukaryotic translation initiation factor 3F.	KRT6A KRT6B KRT14 KRT16 KRT6C	3.17e-09	75	27	5	31527668
Pubmed	Three epidermal and one simple epithelial type II keratin genes map to human chromosome 12.	KRT6A KRT6B KRT14	4.17e-09	5	27	3	1713141
Pubmed	Role for keratins 6 and 17 during wound closure in embryonic mouse skin.	KRT6A KRT6B KRT16	4.17e-09	5	27	3	12557214
Pubmed	Reactive-site-centric chemoproteomics identifies a distinct class of deubiquitinase enzymes.	KRT6A KRT6B KRT14 KRT16 DSG1	5.64e-09	84	27	5	29563501
Pubmed	Stage- and subunit-specific functions of polycomb repressive complex 2 in bladder urothelial formation and regeneration.	KRT6A KRT6B KRT14 KRT16	6.75e-09	29	27	4	28049658
Pubmed	Identification of 14-3-3sigma mutation causing cutaneous abnormality in repeated-epilation mutant mouse.	KRT6A KRT6B KRT14	8.33e-09	6	27	3	16239341
Pubmed	TRIM25 and DEAD-Box RNA Helicase DDX3X Cooperate to Regulate RIG-I-Mediated Antiviral Immunity.	KRT6A KRT6B KRT14 KRT16 DSG1	8.46e-09	91	27	5	34445801
Pubmed	An in vivo comparative study of sonic, desert and Indian hedgehog reveals that hedgehog pathway activity regulates epidermal stem cell homeostasis.	KRT6A KRT6B KRT14	2.33e-08	8	27	3	15371305
Pubmed	Identification of trichoplein, a novel keratin filament-binding protein.	KRT6A KRT14 KRT16	2.33e-08	8	27	3	15731013
Pubmed	Topical Aminosalicylic Acid Improves Keratinocyte Differentiation in an Inducible Mouse Model of Harlequin Ichthyosis.	KRT6A KRT6B KRT14	2.33e-08	8	27	3	33294854
Pubmed	A mutant mouse with severe anemia and skin abnormalities controlled by a new allele of the flaky skin (fsn) locus.	KRT6A KRT6B KRT14	3.49e-08	9	27	3	16093647
Pubmed	RIP4 regulates epidermal differentiation and cutaneous inflammation.	KRT6A KRT6B KRT14	3.49e-08	9	27	3	19626033
Pubmed	Type II keratins precede type I keratins during early embryonic development.	KRT6A KRT6B KRT14	3.49e-08	9	27	3	16180309
Pubmed	Periderm Fate during Palatogenesis: TGF-β and Periderm Dedifferentiation.	KRT6A KRT6B KRT14	3.49e-08	9	27	3	36751050
Pubmed	PHGDH Inhibits Ferroptosis and Promotes Malignant Progression by Upregulating SLC7A11 in Bladder Cancer.	KRT6A KRT6B KRT14 KRT16	4.60e-08	46	27	4	36147463
Pubmed	Charting the molecular network of the drug target Bcr-Abl.	KRT6A KRT6B KRT14 KRT16 KRT6C CNOT1	4.89e-08	266	27	6	19380743
Pubmed	A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies.	KRT6A KRT6B KRT14 KRT16 DSG1 CNOT1	7.21e-08	284	27	6	29459677
Pubmed	EGFR suppresses p53 function by promoting p53 binding to DNA-PKcs: a noncanonical regulatory axis between EGFR and wild-type p53 in glioblastoma.	KRT6B KRT14 KRT16 DSG1	8.87e-08	54	27	4	35474131
Pubmed	RNF208, an estrogen-inducible E3 ligase, targets soluble Vimentin to suppress metastasis in triple-negative breast cancers.	KRT6A KRT6B KRT14 KRT6C	1.11e-07	57	27	4	31862882
Pubmed	Altered keratinocyte differentiation is an early driver of keratin mutation-based palmoplantar keratoderma.	KRT6A KRT6B KRT14 KRT16	1.36e-07	60	27	4	31220272
Pubmed	Lymphotoxin-beta regulates periderm differentiation during embryonic skin development.	KRT6A KRT6B KRT14	1.51e-07	14	27	3	17673451
Pubmed	Defects in Stratum Corneum Desquamation Are the Predominant Effect of Impaired ABCA12 Function in a Novel Mouse Model of Harlequin Ichthyosis.	KRT14 KRT16 DSG1	1.51e-07	14	27	3	27551807
Pubmed	An investigation into the human serum "interactome".	KRT6A KRT6B KRT14 KRT16 CNOT1	1.53e-07	162	27	5	15174051
Pubmed	hnRNPA1 couples nuclear export and translation of specific mRNAs downstream of FGF-2/S6K2 signalling.	KRT6A KRT6B KRT14 KRT16 KRT6C DSG1	2.30e-07	346	27	6	25324306
Pubmed	Adenomatous polyposis coli (APC) is required for normal development of skin and thymus.	KRT6A KRT6B KRT14	4.01e-07	19	27	3	17002498
Pubmed	Ephrin-As, Eph receptors and integrin α3 interact and colocalise at membrane protrusions of U251MG glioblastoma cells.	KRT6A KRT6B KRT14 KRT16 KRT6C	4.04e-07	197	27	5	23686814
Pubmed	Suppression of ACE2 SUMOylation protects against SARS-CoV-2 infection through TOLLIP-mediated selective autophagy.	KRT6B KRT14 KRT16 KRT6C DSG1 CNOT1 PLS1	4.51e-07	641	27	7	36057605
Pubmed	Bcl11b/Ctip2 is required for development of lingual papillae in mice.	KRT6A KRT6B KRT14	5.50e-07	21	27	3	27287879
Pubmed	AP-2 factors act in concert with Notch to orchestrate terminal differentiation in skin epidermis.	KRT6A KRT6B KRT14	5.50e-07	21	27	3	18824566
Pubmed	The functional diversity of epidermal keratins revealed by the partial rescue of the keratin 14 null phenotype by keratin 16.	KRT14 KRT16	5.80e-07	2	27	2	10477769
Pubmed	Aberrant heterodimerization of keratin 16 with keratin 6A in HaCaT keratinocytes results in diminished cellular migration.	KRT6A KRT16	5.80e-07	2	27	2	20403371
Pubmed	A reporter transgene based on a human keratin 6 gene promoter is specifically expressed in the periderm of mouse embryos.	KRT6A KRT6B	5.80e-07	2	27	2	11118885
Pubmed	Mutations of KRT6A are more frequent than those of KRT16 in pachyonychia congenita type 1: report of a novel and a recently reported mutation in two unrelated Chinese families.	KRT6A KRT16	5.80e-07	2	27	2	18489596
Pubmed	Discovery of a novel murine keratin 6 (K6) isoform explains the absence of hair and nail defects in mice deficient for K6a and K6b.	KRT6A KRT6B	5.80e-07	2	27	2	11489919
Pubmed	The two functional keratin 6 genes of mouse are differentially regulated and evolved independently from their human orthologs.	KRT6A KRT6B	5.80e-07	2	27	2	9790766
Pubmed	Delayed wound healing in keratin 6a knockout mice.	KRT6A KRT6B	5.80e-07	2	27	2	10866680
Pubmed	Pachyonychia congenita patients with mutations in KRT6A have more extensive disease compared with patients who have mutations in KRT16.	KRT6A KRT16	5.80e-07	2	27	2	22098151
Pubmed	Introducing a null mutation in the mouse K6alpha and K6beta genes reveals their essential structural role in the oral mucosa.	KRT6A KRT6B	5.80e-07	2	27	2	10953016
Pubmed	The complete cDNA and deduced amino acid sequence of a type II mouse epidermal keratin of 60,000 Da: analysis of sequence differences between type I and type II keratins.	KRT6A KRT6B	5.80e-07	2	27	2	6207530
Pubmed	Expression of MK6a dominant-negative and C-terminal mutant transgenes in mice has distinct phenotypic consequences in the epidermis and hair follicle.	KRT6A KRT6B	5.80e-07	2	27	2	10550543
Pubmed	The mouse keratin 6 isoforms are differentially expressed in the hair follicle, footpad, tongue and activated epidermis.	KRT6A KRT6B	5.80e-07	2	27	2	10550545
Pubmed	cDNA cloning, expression, and assembly characteristics of mouse keratin 16.	KRT14 KRT16	5.80e-07	2	27	2	9822705
Pubmed	Collapse of the keratin filament network through the expression of mutant keratin 6c observed in a case of focal plantar keratoderma.	KRT6A KRT6C	5.80e-07	2	27	2	23662636
Pubmed	Two novel de novo mutations of KRT6A and KRT16 genes in two Chinese pachyonychia congenita pedigrees with fissured tongue or diffuse plantar keratoderma.	KRT6A KRT16	5.80e-07	2	27	2	22668561
Pubmed	Cytokeratins mediate epithelial innate defense through their antimicrobial properties.	KRT6A KRT6B	5.80e-07	2	27	2	23006328
Pubmed	High proliferation and delamination during skin epidermal stratification.	KRT6A KRT6B KRT14	6.36e-07	22	27	3	34050161
Pubmed	A functional reference map of the RNF8 interactome in cancer.	KRT6A KRT6B KRT14 KRT16 DSG1	6.67e-07	218	27	5	35831895
Pubmed	Barx2 functions through distinct corepressor classes to regulate hair follicle remodeling.	KRT6A KRT6B KRT16	8.35e-07	24	27	3	15728386
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	KRT6A KRT6B KRT14 KRT16 KRT6C PCDHGB6 PCDHGA11 PLS1 NUP54	8.41e-07	1442	27	9	35575683
Pubmed	SARS-CoV-2 N Protein Antagonizes Stress Granule Assembly and IFN Production by Interacting with G3BPs to Facilitate Viral Replication.	KRT6A KRT6B KRT14 KRT16 DSG1	1.18e-06	245	27	5	35652658
Pubmed	Mapping Extracellular Protein-Protein Interactions Using Extracellular Proximity Labeling (ePL).	KRT6A KRT6B KRT14 KRT16 DSG1	1.23e-06	247	27	5	39238192
Pubmed	Inhibition of calpain 1 restores plasma membrane stability to pharmacologically rescued Phe508del-CFTR variant.	KRT6A KRT6B KRT14 KRT16 KRT6C DSG1	1.71e-06	488	27	6	31324722
Pubmed	Novel and recurrent mutations in the genes encoding keratins K6a, K16 and K17 in 13 cases of pachyonychia congenita.	KRT6A KRT16	1.74e-06	3	27	2	11886499
Pubmed	Keratin expression provides novel insight into the morphogenesis and function of the companion layer in hair follicles.	KRT6A KRT6B	1.74e-06	3	27	2	17170733
Pubmed	Identification of a cloned sequence activated during multi-stage carcinogenesis in mouse skin.	KRT6A KRT6B	1.74e-06	3	27	2	1713533
Pubmed	Keratin 16 expression defines a subset of epithelial cells during skin morphogenesis and the hair cycle.	KRT14 KRT16	1.74e-06	3	27	2	12445204
Pubmed	A spectrum of mutations in keratins K6a, K16 and K17 causing pachyonychia congenita.	KRT6A KRT16	1.74e-06	3	27	2	17719747
Pubmed	Overcoming functional redundancy to elicit pachyonychia congenita-like nail lesions in transgenic mice.	KRT6A KRT6B	1.74e-06	3	27	2	15601842
Pubmed	Mice expressing a mutant Krt75 (K6hf) allele develop hair and nail defects resembling pachyonychia congenita.	KRT6A KRT6B	1.74e-06	3	27	2	17851587
Pubmed	A group of type I keratin genes on human chromosome 17: characterization and expression.	KRT14 KRT16	1.74e-06	3	27	2	2451124
Pubmed	Cytokeratin 5/6 expression in bladder cancer: association with clinicopathologic parameters and prognosis.	KRT6A KRT6B	1.74e-06	3	27	2	29587848
Pubmed	Onset of re-epithelialization after skin injury correlates with a reorganization of keratin filaments in wound edge keratinocytes: defining a potential role for keratin 16.	KRT14 KRT16	1.74e-06	3	27	2	8636216
Pubmed	A small deletion hotspot in the type II keratin gene mK6irs1/Krt2-6g on mouse chromosome 15, a candidate for causing the wavy hair of the caracul (Ca) mutation.	KRT6A KRT6B	1.74e-06	3	27	2	14573483
Pubmed	Keratin and filaggrin expression in keratoacanthoma.	KRT14 KRT16	1.74e-06	3	27	2	18005116
Pubmed	ACAA2 is a ligand-dependent coactivator for thyroid hormone receptor β1.	KRT6A KRT6B KRT14 KRT16	1.75e-06	113	27	4	34474245
Pubmed	Ets1 blocks terminal differentiation of keratinocytes and induces expression of matrix metalloproteases and innate immune mediators.	KRT6A KRT6B KRT14	1.85e-06	31	27	3	20930145
Pubmed	ZFP750 affects the cutaneous barrier through regulating lipid metabolism.	KRT6A KRT6B KRT14	1.85e-06	31	27	3	37115925
Pubmed	EZH2 interacts with HP1BP3 to epigenetically activate WNT7B that promotes temozolomide resistance in glioblastoma.	APEH KRT6A KRT6B KRT14 KRT16 KRT6C DSG1	2.02e-06	803	27	7	36517590
Pubmed	Transcriptome and phenotypic analysis reveals Gata3-dependent signalling pathways in murine hair follicles.	KRT6A KRT6B KRT14	3.19e-06	37	27	3	17151017
Pubmed	Phosphorylation of human keratin 8 in vivo at conserved head domain serine 23 and at epidermal growth factor-stimulated tail domain serine 431.	KRT6A KRT6C	3.48e-06	4	27	2	9054461
Pubmed	Keratin 6 regulates collective keratinocyte migration by altering cell-cell and cell-matrix adhesion.	KRT6A KRT6B	3.48e-06	4	27	2	30389720
Pubmed	E3 Ligase Trim21 Ubiquitylates and Stabilizes Keratin 17 to Induce STAT3 Activation in Psoriasis.	KRT14 KRT16 KRT6C DSG1	3.55e-06	135	27	4	29859926
Pubmed	Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways.	KRT6A KRT6B KRT14 KRT16 KRT6C DSG1	3.92e-06	564	27	6	21565611
Pubmed	Use of monospecific antisera and cRNA probes to localize the major changes in keratin expression during normal and abnormal epidermal differentiation.	KRT14 KRT16	5.80e-06	5	27	2	2458356
Pubmed	Changes in keratin and filaggrin expression in the skin of chronic proliferative dermatitis (cpdm) mutant mice.	KRT14 KRT16	5.80e-06	5	27	2	9873228
Pubmed	Airway hillocks are injury-resistant reservoirs of unique plastic stem cells.	KRT6A KRT6B	5.80e-06	5	27	2	38693267
Pubmed	The diagnostic utility of D2-40, calretinin, CK5/6, desmin and MOC-31 in the differentiation of mesothelioma from adenocarcinoma in pleural effusion cytology.	KRT6A KRT6B	5.80e-06	5	27	2	23075894
Pubmed	Hair follicle stem cells regulate retinoid metabolism to maintain the self-renewal niche for melanocyte stem cells.	KRT6A KRT6B	5.80e-06	5	27	2	31898934
Pubmed	Skin Barrier Development Depends on CGI-58 Protein Expression during Late-Stage Keratinocyte Differentiation.	KRT14 DSG1	5.80e-06	5	27	2	27725204
Pubmed	CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.	KRT6A KRT6B KRT14 KRT16 KRT6C DSG1	5.86e-06	605	27	6	28977666
Pubmed	Keratin 17 modulates hair follicle cycling in a TNFalpha-dependent fashion.	KRT14 KRT16	8.69e-06	6	27	2	16702408
Pubmed	p63(+)Krt5(+) distal airway stem cells are essential for lung regeneration.	KRT6A KRT6B	8.69e-06	6	27	2	25383540
Pubmed	Keratin 6 is not essential for mammary gland development.	KRT6A KRT6B	8.69e-06	6	27	2	16790075
Pubmed	Identification of functional variants for cleft lip with or without cleft palate in or near PAX7, FGFR2, and NOG by targeted sequencing of GWAS loci.	KRT6A KRT6B	8.69e-06	6	27	2	25704602
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	KRT6A KRT14 KRT16 KRT6C DSG1 CNOT1 NUP54	9.96e-06	1024	27	7	24711643
Pubmed	TRIM26 Induces Ferroptosis to Inhibit Hepatic Stellate Cell Activation and Mitigate Liver Fibrosis Through Mediating SLC7A11 Ubiquitination.	KRT6B KRT14 KRT16	1.13e-05	56	27	3	33869196
Pubmed	Frizzled6 deficiency disrupts the differentiation process of nail development.	KRT6A KRT6B	1.22e-05	7	27	2	23439395
Pubmed	Mouse homologue of skin-specific retroviral-like aspartic protease involved in wrinkle formation.	KRT14 DSG1	1.22e-05	7	27	2	16837463
Pubmed	Prediction of local recurrence, distant metastases, and death after breast-conserving therapy in early-stage invasive breast cancer using a five-biomarker panel.	KRT6A KRT6B	1.22e-05	7	27	2	19720911
Pubmed	Deciphering TGF-β3 function in medial edge epithelium specification and fusion during mouse secondary palate development.	KRT6A KRT6B	1.22e-05	7	27	2	25104574
Interaction	KRT84 interactions	KRT6A KRT6B KRT14 KRT16 KRT6C	5.34e-09	49	27	5	int:KRT84
Interaction	KRT7 interactions	KRT6A KRT6B KRT14 KRT16 KRT6C	6.55e-08	80	27	5	int:KRT7
Interaction	EFNA1 interactions	KRT6A KRT6B KRT14 KRT16 KRT6C	2.33e-07	103	27	5	int:EFNA1
Interaction	EFNA3 interactions	KRT6A KRT6B KRT14 KRT16 KRT6C	2.96e-07	108	27	5	int:EFNA3
Interaction	KRT17 interactions	KRT6A KRT6B KRT14 KRT16 KRT6C DSG1	8.55e-07	252	27	6	int:KRT17
Interaction	KRT19 interactions	KRT6A MLLT6 KRT6B KRT14 KRT16 KRT6C	1.65e-06	282	27	6	int:KRT19
Interaction	DES interactions	KRT6A KRT6B KRT14 KRT16 KRT6C	1.95e-06	158	27	5	int:DES
Interaction	KRT6A interactions	KRT6A KRT6B KRT14 KRT16 KRT6C	2.08e-06	160	27	5	int:KRT6A
Interaction	EIF3F interactions	KRT6A KRT6B KRT14 KRT16 KRT6C NUP54	2.18e-06	296	27	6	int:EIF3F
Interaction	PHTF1 interactions	KRT6A KRT6B KRT6C	2.41e-06	20	27	3	int:PHTF1
Interaction	RNF208 interactions	KRT6A KRT6B KRT14 KRT6C	2.91e-06	75	27	4	int:RNF208
Interaction	KRT6C interactions	KRT6A KRT14 KRT16 KRT6C	3.07e-06	76	27	4	int:KRT6C
Interaction	ZUP1 interactions	KRT6A KRT6B KRT14 KRT16 DSG1	3.13e-06	174	27	5	int:ZUP1
Interaction	KRT75 interactions	KRT6A KRT6B KRT14 KRT16 KRT6C	3.80e-06	181	27	5	int:KRT75
Interaction	KRT5 interactions	KRT6A KRT6B KRT14 KRT16 KRT6C	5.20e-06	193	27	5	int:KRT5
Interaction	PRPH interactions	KRT6A KRT6B KRT14 KRT16 KRT6C	6.81e-06	204	27	5	int:PRPH
Interaction	IQCB1 interactions	KRT6A KRT6B KRT14 KRT16 KRT6C DSG1	7.86e-06	370	27	6	int:IQCB1
Interaction	KRT28 interactions	KRT6A KRT6B KRT6C	8.50e-06	30	27	3	int:KRT28
Interaction	KRT26 interactions	KRT6A KRT6B KRT6C	1.36e-05	35	27	3	int:KRT26
Interaction	KRT25 interactions	KRT6A KRT6B KRT6C	1.36e-05	35	27	3	int:KRT25
Interaction	EFNA4 interactions	KRT6A KRT6B KRT14 KRT16 KRT6C	1.47e-05	239	27	5	int:EFNA4
Interaction	KRT18 interactions	KRT6A KRT6B KRT14 KRT16 KRT6C CNOT1	1.59e-05	419	27	6	int:KRT18
Interaction	KIFC3 interactions	KRT6A KRT6B KRT14 KRT16 KRT6C	1.89e-05	252	27	5	int:KIFC3
Interaction	KRT8 interactions	KRT6A KRT6B KRT14 KRT16 KRT6C CNOT1	2.13e-05	441	27	6	int:KRT8
Interaction	TCHP interactions	KRT6A KRT14 KRT16 NUP54	2.66e-05	131	27	4	int:TCHP
Interaction	KRT6B interactions	KRT6A KRT6B KRT14 KRT16	2.75e-05	132	27	4	int:KRT6B
Interaction	TIMP2 interactions	KRT6A KRT6B KRT14 KRT16 DSG1	2.98e-05	277	27	5	int:TIMP2
Interaction	PUS10 interactions	KRT14 KRT16	3.61e-05	7	27	2	int:PUS10
Interaction	KRT81 interactions	KRT14 KRT16 PLS1	4.80e-05	53	27	3	int:KRT81
Interaction	CBL interactions	KRT6A KRT6B KRT14 KRT16 KRT6C PLS1	5.12e-05	516	27	6	int:CBL
Interaction	UBASH3B interactions	KRT6A KRT6B KRT14 KRT16	5.41e-05	157	27	4	int:UBASH3B
Interaction	KRT72 interactions	KRT6A KRT14 KRT16	6.63e-05	59	27	3	int:KRT72
Interaction	KRT79 interactions	KRT6A KRT14 KRT16	6.63e-05	59	27	3	int:KRT79
Interaction	KRT20 interactions	KRT6A KRT6B KRT6C	8.07e-05	63	27	3	int:KRT20
Interaction	KRT15 interactions	KRT6A KRT6B KRT6C NUP54	8.81e-05	178	27	4	int:KRT15
Interaction	DDX39B interactions	KRT6A KRT6B KRT14 KRT16 KRT6C DSG1	8.89e-05	570	27	6	int:DDX39B
Interaction	THRB interactions	KRT6A KRT14 KRT16 CNOT1	1.04e-04	186	27	4	int:THRB
Interaction	CRK interactions	KLF15 KRT6A KRT6B KRT14 KRT16	1.18e-04	370	27	5	int:CRK
Interaction	KRT14 interactions	KRT6A KRT6B KRT14 KRT6C	1.18e-04	192	27	4	int:KRT14
Interaction	WTAP interactions	KRT6A KRT6B KRT14 KRT16	1.23e-04	194	27	4	int:WTAP
Interaction	KRT16 interactions	KRT6A KRT6B KRT16 KRT6C	1.30e-04	197	27	4	int:KRT16
Interaction	KRT36 interactions	KRT6A KRT6B KRT6C	1.30e-04	74	27	3	int:KRT36
Interaction	KRT27 interactions	KRT6A KRT6B KRT6C NUP54	1.44e-04	202	27	4	int:KRT27
Interaction	ALB interactions	KRT6A KRT6B KRT14 KRT16 CNOT1	1.52e-04	391	27	5	int:ALB
Interaction	FGD5 interactions	KRT6A KRT6B KRT14 KRT16	1.58e-04	207	27	4	int:FGD5
Interaction	TTC23 interactions	KRT6A KRT14 KRT16 CNOT1	1.61e-04	208	27	4	int:TTC23
Interaction	INPPL1 interactions	KRT6B KRT14 KRT16 KRT6C	1.79e-04	214	27	4	int:INPPL1
Interaction	DDX3X interactions	KRT6A KRT6B KRT14 KRT16 DSG1 CNOT1	1.84e-04	651	27	6	int:DDX3X
Interaction	HNRNPA1 interactions	KRT6A KRT6B KRT14 KRT16 KCNA6 KRT6C DSG1	1.90e-04	945	27	7	int:HNRNPA1
Interaction	KRT76 interactions	KRT6A KRT14 KRT16	1.90e-04	84	27	3	int:KRT76
Interaction	EPS15 interactions	KRT6A MLLT6 KRT14 KRT16	1.99e-04	220	27	4	int:EPS15
Interaction	RNF8 interactions	KRT6A KRT6B KRT14 KRT16 DSG1	2.15e-04	421	27	5	int:RNF8
Interaction	KRT3 interactions	KRT6A KRT14 KRT16	2.18e-04	88	27	3	int:KRT3
Interaction	KRT33B interactions	KRT6B KRT6C NUP54	2.57e-04	93	27	3	int:KRT33B
Interaction	KRT77 interactions	KRT6A KRT14 KRT16	2.82e-04	96	27	3	int:KRT77
Interaction	ZBTB22 interactions	MLLT6 ZBTB22	3.24e-04	20	27	2	int:ZBTB22
Interaction	CHD3 interactions	KRT6A KRT6B KRT14 KRT16 KRT6C DSG1	4.14e-04	757	27	6	int:CHD3
Interaction	KRT35 interactions	KRT6A KRT6B KRT6C	4.32e-04	111	27	3	int:KRT35
Interaction	KRT12 interactions	KRT6A KRT6B	4.68e-04	24	27	2	int:KRT12
Interaction	KRT13 interactions	KRT6A KRT6B KRT6C	4.91e-04	116	27	3	int:KRT13
Interaction	ACE2 interactions	KRT6B KRT14 KRT16 KRT6C DSG1 CNOT1 PLS1	4.95e-04	1106	27	7	int:ACE2
Interaction	METTL3 interactions	KRT6A KRT14 KRT16 DSG1	5.46e-04	287	27	4	int:METTL3
Interaction	GAS8 interactions	KRT14 KRT16 ZBTB22	6.11e-04	125	27	3	int:GAS8
Interaction	CIBAR1 interactions	KRT6A KRT14 KRT16	7.98e-04	137	27	3	int:CIBAR1
Interaction	TRIM54 interactions	KRT6A KRT6B KRT6C NUP54	8.30e-04	321	27	4	int:TRIM54
Interaction	MKS1 interactions	KRT6A KRT14 KRT16	8.32e-04	139	27	3	int:MKS1
Interaction	PCDHA9 interactions	PCDHGB6 PCDHGA11	8.36e-04	32	27	2	int:PCDHA9
Interaction	CYLD interactions	MUC19 KRT6A KRT6B KRT14 KRT16 DSG1	8.53e-04	868	27	6	int:CYLD
Interaction	CUL2 interactions	KRT6A KRT14 KRT16 KRT6C DSG1	1.01e-03	591	27	5	int:CUL2
Interaction	HEXIM1 interactions	KRT6A KRT6B KRT14 KRT16 KRT6C PLS1	1.11e-03	913	27	6	int:HEXIM1
Interaction	KRT74 interactions	KRT6A KRT16	1.12e-03	37	27	2	int:KRT74
Interaction	PIAS1 interactions	KRT6A KRT14 KRT16 RNF19A	1.18e-03	353	27	4	int:PIAS1
Interaction	AIRIM interactions	KLF15 KRT16 NUP54	1.23e-03	159	27	3	int:AIRIM
Interaction	CHD4 interactions	KRT6A KRT6B KRT14 KRT16 KRT6C DSG1	1.28e-03	938	27	6	int:CHD4
Interaction	NUP43 interactions	MUC19 MLLT6 DSG1 CNOT1 NUP54	1.29e-03	625	27	5	int:NUP43
Interaction	KRT71 interactions	KRT6A KRT16	1.51e-03	43	27	2	int:KRT71
Interaction	KRT38 interactions	KRT6A KRT6B KRT6C	1.54e-03	172	27	3	int:KRT38
Interaction	PCDHGB2 interactions	PCDHGB6 PCDHGA11	1.58e-03	44	27	2	int:PCDHGB2
Interaction	CCDC8 interactions	KRT6A KRT14 KRT16 DSG1 CNOT1	1.60e-03	656	27	5	int:CCDC8
Interaction	PHGDH interactions	KRT6A KRT6B KRT14 KRT16	1.63e-03	385	27	4	int:PHGDH
Interaction	RLIM interactions	KRT6A KRT14 KRT16 DSG1	1.74e-03	392	27	4	int:RLIM
Interaction	KRT10 interactions	KRT6A KRT6B KRT16	1.95e-03	187	27	3	int:KRT10
Interaction	NEFM interactions	MLLT6 KRT14 KRT16	2.04e-03	190	27	3	int:NEFM
Interaction	DIRAS2 interactions	KRT6A KRT16	2.20e-03	52	27	2	int:DIRAS2
Interaction	DSP interactions	KRT6A KRT14 KRT16 DSG1	2.29e-03	423	27	4	int:DSP
Interaction	TRIM26 interactions	KRT6B KRT14 KRT16	2.33e-03	199	27	3	int:TRIM26
Interaction	KRT24 interactions	KRT6B KRT6C	2.37e-03	54	27	2	int:KRT24
Interaction	AP2M1 interactions	KRT6A KRT6B KRT14 KRT16	2.43e-03	430	27	4	int:AP2M1
Interaction	TFCP2 interactions	KRT6A KRT6B KRT14 KRT16	2.56e-03	436	27	4	int:TFCP2
Interaction	TEDC2 interactions	KRT6A KRT14 KRT16	2.57e-03	206	27	3	int:TEDC2
Interaction	LATS1 interactions	KRT6A KRT16 KRT6C DSG1	2.64e-03	440	27	4	int:LATS1
Interaction	YAP1 interactions	KLF15 KRT6A KRT6B KRT14 KRT16 CNOT1	2.81e-03	1095	27	6	int:YAP1
Interaction	COPS5 interactions	KRT6A KRT6B KRT14 KRT16 KRT6C DSG1	2.90e-03	1102	27	6	int:COPS5
Interaction	KRT31 interactions	KRT6A KRT6B KRT6C PLS1	2.93e-03	453	27	4	int:KRT31
Interaction	OIP5 interactions	KRT6B KRT14 NUP54	2.98e-03	217	27	3	int:OIP5
Interaction	KRT85 interactions	KRT14 KRT16	3.01e-03	61	27	2	int:KRT85
Interaction	LARP7 interactions	KRT6A KRT6B KRT14 KRT16 KRT6C DSG1	3.04e-03	1113	27	6	int:LARP7
Interaction	KRT4 interactions	KRT14 KRT16	3.11e-03	62	27	2	int:KRT4
Interaction	KRT73 interactions	KRT6A KRT16	3.31e-03	64	27	2	int:KRT73
Cytoband	12q13.13	KRT6A KRT6B KRT6C	8.47e-06	67	27	3	12q13.13
Cytoband	Ensembl 112 genes in cytogenetic band chr12q13	KRT6A KRT6B HOXC6 KRT6C	1.05e-04	423	27	4	chr12q13
Cytoband	Ensembl 112 genes in cytogenetic band chr16q21	CNOT1 CDH8	9.98e-04	79	27	2	chr16q21
Cytoband	5q31	PCDHGB6 PCDHGA11	2.10e-03	115	27	2	5q31
Cytoband	Ensembl 112 genes in cytogenetic band chr17q21	KRT14 KRT16 UBE2Z	2.64e-03	473	27	3	chr17q21
Cytoband	Ensembl 112 genes in cytogenetic band chr3q21	KLF15 SLC12A8	4.00e-03	160	27	2	chr3q21
Cytoband	Ensembl 112 genes in cytogenetic band chr5q31	PCDHGB6 PCDHGA11	1.32e-02	298	27	2	chr5q31
GeneFamily	Keratins, type II	KRT6A KRT6B KRT6C	3.88e-06	27	21	3	609
GeneFamily	Keratins, type I	KRT14 KRT16	4.77e-04	28	21	2	608
GeneFamily	Clustered protocadherins	PCDHGB6 PCDHGA11	2.48e-03	64	21	2	20
Coexpression	DESCARTES_MAIN_FETAL_SQUAMOUS_EPITHELIAL_CELLS	KRT6A KRT6B KRT14 KRT16 KRT6C	1.98e-07	129	27	5	M40122
Coexpression	TABULA_MURIS_SENIS_TONGUE_KERATINOCYTE_AGEING	KRT6A KRT6B KRT14 KRT16	3.16e-07	56	27	4	MM3852
Coexpression	DESCARTES_FETAL_STOMACH_SQUAMOUS_EPITHELIAL_CELLS	KRT6A KRT6B KRT16 KRT6C	6.55e-07	67	27	4	M40299
Coexpression	RICKMAN_TUMOR_DIFFERENTIATED_WELL_VS_MODERATELY_DN	KRT6B KRT14 KRT16 DSG1	5.32e-06	113	27	4	M9524
Coexpression	JAEGER_METASTASIS_DN	KRT6A KRT6B KRT14 KRT16 DSG1	6.24e-06	260	27	5	M10702
Coexpression	GU_PDEF_TARGETS_DN	KRT6A KRT6B KRT6C	9.39e-06	40	27	3	M10480
Coexpression	BUSSLINGER_ESOPHAGEAL_LATE_SUPRABASAL_CELLS	KRT6A KRT6B KRT6C DSG1	1.24e-05	140	27	4	M40004
Coexpression	SMID_BREAST_CANCER_RELAPSE_IN_BONE_DN	KRT6A KRT6B KRT14 KRT16 DSG1	1.81e-05	324	27	5	M2700
Coexpression	HUPER_BREAST_BASAL_VS_LUMINAL_UP	KRT6A KRT16 DSG1	2.21e-05	53	27	3	M13422
Coexpression	HOLLERN_SQUAMOUS_BREAST_TUMOR	KRT6A KRT14 KRT16 KRT6C	2.86e-05	173	27	4	M650
Coexpression	HOLLERN_SQUAMOUS_BREAST_TUMOR	KRT6A KRT6B KRT14 KRT16	5.43e-05	204	27	4	MM966
Coexpression	JI_CARCINOGENESIS_BY_KRAS_AND_STK11_UP	KRT6A KRT6B	7.91e-05	13	27	2	MM743
Coexpression	MURAKAMI_UV_RESPONSE_1HR_UP	KRT14 DSG1	1.06e-04	15	27	2	M13308
Coexpression	ONDER_CDH1_TARGETS_2_DN	KRT6A KRT6B SLC12A8 KRT14 KRT16	1.09e-04	473	27	5	M4306
Coexpression	TABULA_MURIS_SENIS_GONADAL_ADIPOSE_TISSUE_B_CELL_AGEING	KRT6A KRT6B KRT14	1.47e-04	100	27	3	MM3697
Coexpression	MURAKAMI_UV_RESPONSE_24HR	KRT14 DSG1	1.92e-04	20	27	2	M17175
Coexpression	PECE_MAMMARY_STEM_CELL_UP	KRT6B KRT14 KRT16	3.89e-04	139	27	3	M2534
Coexpression	SMID_BREAST_CANCER_BASAL_UP	KRT6A KRT6B KRT14 KRT16 DSG1	5.15e-04	662	27	5	M8124
Coexpression	TABULA_MURIS_SENIS_TONGUE_BASAL_CELL_OF_EPIDERMIS_AGEING	KRT6A KRT6B KRT16	5.65e-04	158	27	3	MM3851
Coexpression	OUELLET_CULTURED_OVARIAN_CANCER_INVASIVE_VS_LMP_DN	KRT6A CDH8	5.95e-04	35	27	2	M13220
Coexpression	RICKMAN_TUMOR_DIFFERENTIATED_WELL_VS_POORLY_DN	KRT6A KRT6B KRT14 KRT16	6.10e-04	384	27	4	M12527
CoexpressionAtlas	AravindRamakr_EmbryoidBody-LF_top-relative-expression-ranked_500_k-means-cluster#4	KRT6A KRT6B KRT14 KRT16 KRT6C	1.07e-08	59	27	5	Arv_EB-LF_500_K4
CoexpressionAtlas	Progenitor-Cell-Biology-Consortium_reference_BronchioEpithel_top-relative-expression-ranked_100	KRT6A KRT6B KRT14 KRT16 KRT6C	1.41e-07	98	27	5	PCBC_ctl_BronchioEpithel_100
CoexpressionAtlas	Progenitor-Cell-Biology-Consortium_reference_SmallAirwayEpithel_top-relative-expression-ranked_100	KRT6A KRT6B KRT14 KRT16 KRT6C	1.41e-07	98	27	5	PCBC_ctl_SmallAirwayEpithel_100
CoexpressionAtlas	AravindRamakr_EmbryoidBody-LF_top-relative-expression-ranked_1000_k-means-cluster#5	KRT6A KRT6B KRT14 KRT16 KRT6C	4.38e-07	123	27	5	Arv_EB-LF_1000_K5
CoexpressionAtlas	Progenitor-Cell-Biology-Consortium_induced-Mesoderm_fromBlastocyst-derived-humanEmbryonicStemCells_top-relative-expression-ranked_1000	KLF15 KRT6A KRT6B SLC12A8 KRT14 MARVELD3 KRT16 KRT6C CDH8	1.84e-06	969	27	9	PCBC_MESO-5_blastocyst_1000
CoexpressionAtlas	AravindRamakr_EmbryoidBody-LF_top-relative-expression-ranked_2500_k-means-cluster#3	KRT6A KRT6B SLC12A8 KRT14 KRT16 KRT6C	2.77e-06	325	27	6	Arv_EB-LF_2500_K3
CoexpressionAtlas	AravindRamakr_EmbryoidBody-LF_top-relative-expression-ranked_1000	KRT6A KRT6B SLC12A8 KRT14 HOXC6 KRT16 KRT6C PCDHGB6	2.04e-05	981	27	8	Arv_EB-LF_1000
CoexpressionAtlas	Progenitor-Cell-Biology-Consortium_reference_BronchioEpithel_top-relative-expression-ranked_500	KRT6A KRT6B KRT14 MARVELD3 KRT16 KRT6C	3.07e-05	496	27	6	PCBC_ctl_BronchioEpithel_500
CoexpressionAtlas	AravindRamakr_EmbryoidBody-LF_top-relative-expression-ranked_500	KRT6A KRT6B KRT14 HOXC6 KRT16 KRT6C	3.07e-05	496	27	6	Arv_EB-LF_500
CoexpressionAtlas	BM Top 100 - vagina	KRT6A KRT6B KRT14	1.21e-04	76	27	3	BM Top 100 - vagina
CoexpressionAtlas	BM Top 100 - tongue superior part w_papillae	KRT6A KRT6B KRT14	1.36e-04	79	27	3	BM Top 100 - tongue superior part w_papillae
CoexpressionAtlas	BM Top 100 - oral mucosa	KRT6B KRT16 DSG1	1.57e-04	83	27	3	BM Top 100 - oral mucosa
CoexpressionAtlas	BM Top 100 - nipple cross-section	KRT6B HOXC6 DSG1	1.63e-04	84	27	3	BM Top 100 - nipple cross-section
CoexpressionAtlas	BM Top 100 - esophagus	KRT6A KRT6B KRT14	1.75e-04	86	27	3	BM Top 100 - esophagus
CoexpressionAtlas	esophagus	KRT6A KRT6B KRT16 KRT6C	2.54e-04	247	27	4	esophagus
CoexpressionAtlas	Progenitor-Cell-Biology-Consortium_reference_SmallAirwayEpithel_top-relative-expression-ranked_500	KRT6A KRT6B KRT14 KRT16 KRT6C	3.50e-04	493	27	5	PCBC_ctl_SmallAirwayEpithel_500
CoexpressionAtlas	DevelopingLowerUrinaryTract_e15.5_ureteral tissue_emap-8234_k-means-cluster#3_top-relative-expression-ranked_500	KRT6A KRT14	4.59e-04	25	27	2	gudmap_developingLowerUrinaryTract_e15.5_ureteral tissue_500_k3
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ Genital tubercle_emap-6706_k-means-cluster#3_top-relative-expression-ranked_100	KRT6A KRT14	5.36e-04	27	27	2	gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle_100_k3
CoexpressionAtlas	ratio_induced-DefinitiveEndoderm_vs_StemCell_top-relative-expression-ranked_1000_k-means-cluster#3	KRT14 KRT16 RNF19A PKHD1L1	6.68e-04	319	27	4	ratio_DE_vs_SC_1000_K3
CoexpressionAtlas	ratio_induced-Mesoderm_vs_StemCell_top-relative-expression-ranked_1000_k-means-cluster#4	KRT6A KRT14 RNF19A	1.00e-03	156	27	3	ratio_MESO_vs_SC_1000_K4
CoexpressionAtlas	Progenitor-Cell-Biology-Consortium_reference_BronchSmoothMuscl_top-relative-expression-ranked_1000	KRT6A KRT6B KRT14 KRT16 KRT6C PCDHGA11	1.23e-03	981	27	6	PCBC_ctl_BronchSmoothMuscl_1000
CoexpressionAtlas	DevelopingLowerUrinaryTract_e13.5_bladder neck-urethr epithel_emap-30875_top-relative-expression-ranked_200	KRT6A KRT14 MARVELD3	1.24e-03	168	27	3	gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr epithel_200
CoexpressionAtlas	Progenitor-Cell-Biology-Consortium_reference_SmallAirwayEpithel_top-relative-expression-ranked_1000	KRT6A KRT6B KRT14 MARVELD3 KRT16 KRT6C	1.27e-03	987	27	6	PCBC_ctl_SmallAirwayEpithel_1000
CoexpressionAtlas	Progenitor-Cell-Biology-Consortium_reference_BronchioEpithel_top-relative-expression-ranked_1000	KRT6A KRT6B KRT14 MARVELD3 KRT16 KRT6C	1.29e-03	990	27	6	PCBC_ctl_BronchioEpithel_1000
ToppCell	TCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Non-Papillary_Muscle_Invasive_Urothelial_Carcinoma-6\|TCGA-Bladder / Sample_Type by Project: Shred V9	KRT6A KRT6B KRT14 KRT16 KRT6C DSG1	7.65e-10	171	27	6	0e78389f8f3d54570a6deb3dd307b865b46307e9
ToppCell	TCGA-Head_and_Esophagus\|World / Sample_Type by Project: Shred V9	KRT6A KRT6B KRT14 KRT16 KRT6C DSG1	7.92e-10	172	27	6	eb18aa179db1818f408c38e442ecfed8582d7dbc
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)-Club_(nasal)_L.0.2.3.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	BRINP2 KRT6A KRT6B KRT14 KRT16 KRT6C	1.31e-09	187	27	6	a6a112689d1c9049f57935ad9d2f4955538427de
ToppCell	TCGA-Skin-Primary_Tumor\|TCGA-Skin / Sample_Type by Project: Shred V9	KRT6A KRT6B KRT14 KRT16 KRT6C DSG1	1.44e-09	190	27	6	e2b26a03c6ab24d9b0f4150c47597be37767d86e
ToppCell	TCGA-Skin-Primary_Tumor-Melanoma-Skin_Cutaneous_Melanoma\|TCGA-Skin / Sample_Type by Project: Shred V9	KRT6A KRT6B KRT14 KRT16 KRT6C DSG1	1.44e-09	190	27	6	3188c7bd225cbcf46a21e2fb784336cdd9665995
ToppCell	TCGA-Skin-Primary_Tumor-Melanoma\|TCGA-Skin / Sample_Type by Project: Shred V9	KRT6A KRT6B KRT14 KRT16 KRT6C DSG1	1.44e-09	190	27	6	01fb45add4661bc86cd0a34fac35177907152dbb
ToppCell	Smart-seq2-tissue-resident_(Smart-seq2)-myeloid-myeloid_monocytic\|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	KRT6A KRT6B KRT14 KRT16 KRT6C DSG1	1.74e-09	196	27	6	03de28e1c963e99623e8b0e33bf2e8ef67dc3baa
ToppCell	Smart-seq2-tissue-resident_(Smart-seq2)-myeloid-myeloid_monocytic-leukocyte\|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	KRT6A KRT6B KRT14 KRT16 KRT6C DSG1	1.79e-09	197	27	6	e621d4f9d4ba5e3ef17d2b477e5e14ea0251147e
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid-myeloid_monocytic-leukocyte\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	KRT6A KRT6B KRT14 KRT16 KRT6C RNF19A	1.79e-09	197	27	6	d968d7d5608b175bb567ea3a315bf473ec3be459
ToppCell	distal-1-Epithelial-Proliferating_Basal\|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	KRT6A KRT6B KRT14 MARVELD3 KRT16 KRT6C	1.90e-09	199	27	6	93450257180d918c310bca7b5defc74390c48091
ToppCell	distal-Epithelial-Proliferating_Basal-1\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	KRT6A KRT6B KRT14 MARVELD3 KRT16 KRT6C	1.96e-09	200	27	6	cc31e8c28d01e6757c5dd7f485db6acf7409a47e
ToppCell	distal-Epithelial-Proliferating_Basal\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	KRT6A KRT6B KRT14 MARVELD3 KRT16 KRT6C	1.96e-09	200	27	6	25cc494ef831511840d8c02ec1bd086635cc7edd
ToppCell	TCGA-Cervix-Primary_Tumor-Cervical_Carcinoma-Keratinizing_Cervical_Squamous_Cell_Carcinoma\|TCGA-Cervix / Sample_Type by Project: Shred V9	KRT6A KRT6B KRT14 KRT16 KRT6C	4.58e-08	164	27	5	de1646dbcf2a10b48e021acf7dc63e803e6a47ce
ToppCell	TCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Squamous_Cell_Carcinoma-5\|TCGA-Lung / Sample_Type by Project: Shred V9	KRT6A KRT6B KRT14 KRT16 KRT6C	6.70e-08	177	27	5	a0c7d08469c513cecf87777c19876884f1511570
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KRT6A KRT6B KRT14 KRT16 KRT6C	7.70e-08	182	27	5	007fa56ed8b91f9af0df2114c00410b2f6cec8b6
ToppCell	TCGA-Skin-Primary_Tumor-Melanoma-Skin_Cutaneous_Melanoma-6\|TCGA-Skin / Sample_Type by Project: Shred V9	KRT6A KRT6B KRT16 KRT6C DSG1	8.81e-08	187	27	5	2ca7928baf0c5e61f7294ed05e6e6f0e0adf9d3f
ToppCell	TCGA-Cervix-Primary_Tumor-Cervical_Carcinoma\|TCGA-Cervix / Sample_Type by Project: Shred V9	KRT6A KRT6B KRT14 KRT16 KRT6C	9.29e-08	189	27	5	533c302df467d13ab639232daf4f8cafb808260b
ToppCell	TCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Squamous_Cell_Carcinoma\|TCGA-Lung / Sample_Type by Project: Shred V9	KRT6A KRT6B KRT14 KRT16 KRT6C	9.29e-08	189	27	5	aa4f7d7a5196e5ae481ebc2549de8e3f0ef6e6be
ToppCell	5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KRT6A KRT6B KRT14 KRT16 KRT6C	1.14e-07	197	27	5	fb272c9c60ee3d980e528044dc567b4925a23da6
ToppCell	5'-Airway_Nasal-Epithelial-Airway_epithelium\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KRT6A KRT6B KRT14 KRT16 KRT6C	1.14e-07	197	27	5	61c0d78b29dc4ad8a84172cbfcdab03f31351d0e
ToppCell	distal-1-Epithelial-Basal\|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	KRT6A KRT6B KRT14 KRT16 KRT6C	1.14e-07	197	27	5	25a2ccc98b973611de0d920b1b455d0b40f0d37f
ToppCell	5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KRT6A KRT6B KRT14 KRT16 KRT6C	1.14e-07	197	27	5	dcabea5c50c133c9a4e294e447462d0393174ea7
ToppCell	distal-Epithelial-Basal-1\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	KRT6A KRT6B KRT14 KRT16 KRT6C	1.14e-07	197	27	5	75b4292ce2ad7f9c8b6a4781e1cb71f5b18b74e3
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KRT6A KRT6B KRT14 KRT16 KRT6C	1.14e-07	197	27	5	2430f31d9312338e0ca23bfc6bdb0365340860fd
ToppCell	5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.2.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KRT6A KRT6B KRT14 KRT16 KRT6C	1.17e-07	198	27	5	e06d41a7254a09e037ec404be2d8c352d5cbd7f4
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-Plasma_B\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	KRT6A KRT6B KRT16 KRT6C PKHD1L1	1.17e-07	198	27	5	96236fa22545f6f4ff3aa8dc002963db8a3468ce
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-Plasma_B-Plasma_B-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	KRT6A KRT6B KRT16 KRT6C PKHD1L1	1.17e-07	198	27	5	9e0fdd63069d17430cdc25bf4ffc762afd5e1728
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-Plasma_B-Plasma_B\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	KRT6A KRT6B KRT16 KRT6C PKHD1L1	1.17e-07	198	27	5	7eb521af938c2609a85d27e2aa7d4317ad6e1e44
ToppCell	Smart-seq2-tissue-resident_(Smart-seq2)\|Smart-seq2 / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	KRT6A KRT6B KRT14 KRT16 KRT6C	1.20e-07	199	27	5	8be7cb9d8b4f9707efb69c681c40e683fcd810e5
ToppCell	390C-Epithelial_cells-Epithelial-H_(AT1)-\|390C / Donor, Lineage, Cell class and subclass (all cells)	KRT6A KRT6B KRT16 ERVW-1	2.54e-06	160	27	4	18ae6822915d16699beb9047baeef9b006901a35
ToppCell	390C-Epithelial_cells-Epithelial-H_(AT1)\|390C / Donor, Lineage, Cell class and subclass (all cells)	KRT6A KRT6B KRT16 ERVW-1	2.54e-06	160	27	4	830f17bad94de05612fe6d53d39e42a4b3f3e2f3
ToppCell	facs-Heart-LA-24m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT6A KRT6B KRT14 KRT16	2.60e-06	161	27	4	248487415a0601d57ef2a6692e22a61368d0b9c8
ToppCell	(00)_Basal-(1)_24hpi\|(00)_Basal / shred by cell type and Timepoint	KRT6A KRT6B KRT14 KRT16	3.46e-06	173	27	4	a8e62e7d8baf6af691acd5c50deedbadc119ceba
ToppCell	PND07-Epithelial-Epithelial_Airway-Basal-Basal-Basal_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KRT6A KRT6B KRT14 HOXC6	3.46e-06	173	27	4	1b2508cc890430bd4b2cf232c633928edb86c57e
ToppCell	wk_20-22-Epithelial-Proximal_epithelial-Squamous\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	KRT6A KRT6B KRT14 KRT16	3.54e-06	174	27	4	0a4721248ec89bc98ebe119de6e19fbfca8b5098
ToppCell	wk_15-18-Epithelial-Proximal_epithelial-SMG_basal_1\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	KRT6A KRT6B KRT14 KRT6C	3.54e-06	174	27	4	aceca0a22bb1e380835e792681cfc9b752fb5496
ToppCell	facs-Marrow-T-cells-24m-Hematologic-hematopoietic_stem_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BRINP2 KRT6A KRT14 PLS1	3.62e-06	175	27	4	0a01e0104cfa3091bc05b0f1d087c941688169a5
ToppCell	facs-Trachea-18m\|Trachea / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KRT6A KRT6B KRT14 KRT16	3.79e-06	177	27	4	68c9a8a82c956cbfdf03b44984c97f978aaaf80f
ToppCell	facs-Trachea-nan-18m\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT6A KRT6B KRT14 KRT16	3.79e-06	177	27	4	fc30276903bcb1e95ae76f6cee3d17408158941a
ToppCell	PND07-Epithelial-Epithelial_Airway-Basal\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KRT6A KRT6B KRT14 HOXC6	4.14e-06	181	27	4	f50561fdacfb83ba85fe6476e7cbc2bad1ebc826
ToppCell	PND07-Epithelial-Epithelial_Airway-Basal-Basal\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KRT6A KRT6B KRT14 HOXC6	4.14e-06	181	27	4	6b43dcaeeb02ad5900772b6f16f1581847050e38
ToppCell	droplet-Heart-4Chambers-21m-Neuronal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT6A KRT14 MARVELD3 KCNA6	4.32e-06	183	27	4	a046b569bc10083d471b420eb2c6fee93437602d
ToppCell	droplet-Heart-4Chambers-21m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT6A KRT14 MARVELD3 KCNA6	4.32e-06	183	27	4	4de2082dca2569d3aac3c9b466f27971c82d302b
ToppCell	droplet-Tongue-nan-24m-Epithelial-suprabasal\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT6A KRT6B KRT14 KRT16	4.61e-06	186	27	4	2913b5fd0617d024d600ba7015ec7b1961dade83
ToppCell	facs-Trachea-nan-18m-Epithelial\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT6A KRT6B KRT14 KRT16	4.71e-06	187	27	4	8882a638af7165b2910ba8e932d55475d7bfb003
ToppCell	wk_08-11-Epithelial-Proximal_epithelial-Proximal_secretory_2\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	KRT6A KRT6B KRT16 KRT6C	4.81e-06	188	27	4	07705bed928683470a52c8ccfa40ffb9a0971318
ToppCell	facs-Tongue-nan-24m-Epithelial-suprabasal\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT6A KRT6B KRT14 KRT16	4.81e-06	188	27	4	ed35e438796cef302b6787c111753425922792dc
ToppCell	droplet-Tongue-Unstain-18m-Epithelial-keratinocyte\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT6A KRT6B KRT14 KRT16	4.91e-06	189	27	4	7ee9b00a8bd46f2da9218623bb2617b2e585f9d5
ToppCell	facs-Trachea-18m-Epithelial-airway_epithelial\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KRT6A KRT6B KRT14 KRT16	5.12e-06	191	27	4	cd4e2e883c4955fb2d875e41bb6ebc680994dc8c
ToppCell	facs-Trachea-nan-18m-Epithelial-new-cluster\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT6A KRT6B KRT14 KRT16	5.22e-06	192	27	4	e4fb3f18da7dc6a835023db69a8d99737c39ef86
ToppCell	facs-Trachea-18m-Epithelial\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KRT6A KRT6B KRT14 KRT16	5.22e-06	192	27	4	c5823c5d4c58a4e9121a4b7d7256481d6d9e9b7f
ToppCell	facs-Trachea-nan-18m-Epithelial-keratinocyte\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT6A KRT6B KRT14 KRT16	5.22e-06	192	27	4	4530b3028928d089b3a71eb19a4df237f58a50ae
ToppCell	droplet-Tongue-Unstain-18m-Epithelial-suprabasal\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT6A KRT6B KRT14 KRT16	5.33e-06	193	27	4	f074ebf9c5c53d8589d66b0109505f30baa1af81
ToppCell	droplet-Tongue-nan-3m-Epithelial-suprabasal\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT6A KRT6B KRT14 KRT16	5.33e-06	193	27	4	a7002acf3be76b2cc6fc9364176f6b0d3bd27d9c
ToppCell	NS-critical-d_0-4-Epithelial-Squamous\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	KRT6A KRT6B KRT14 KRT16	5.44e-06	194	27	4	614d0c25b56957c70f397abb169fd2a860eb1c06
ToppCell	facs-Trachea-18m-Epithelial-airway_epithelial-keratinocyte-new-cluster\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KRT6A KRT6B KRT14 KRT16	5.44e-06	194	27	4	b847c5b4e8914b1c306bfff3d7119c32063784a8
ToppCell	facs-Trachea-18m-Epithelial-airway_epithelial-keratinocyte\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KRT6A KRT6B KRT14 KRT16	5.44e-06	194	27	4	bd94d30584128628b34ed8c3857ce103586cfe2e
ToppCell	AT1\|World / shred by cell class for parenchyma	KRT6A KRT6B KRT14 KRT16	5.67e-06	196	27	4	2bc487f8a109a6961ebff111dec79c2227ea60ac
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KRT6A KRT6B KRT16 KRT6C	5.67e-06	196	27	4	279f43deeba4528cd63f5217a8441b5452bf0b16
ToppCell	NS-control-d_0-4-Epithelial-Squamous\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	KRT6A KRT6B KRT14 KRT16	5.78e-06	197	27	4	ab965a0ba87efd3329d24a1ec123985f46fc17c0
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-Reg_T-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	KRT6A KRT6B KRT16 KRT6C	5.78e-06	197	27	4	9ee927d005eb17843e2516c8006eb192c6ad2af8
ToppCell	control-Epithelial-Squamous\|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	KRT6A KRT6B KRT14 KRT16	5.90e-06	198	27	4	6ba669ac1ed275ae309054941b1457e315766faa
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KRT6A KRT6B KRT14 KRT16	5.90e-06	198	27	4	89ec1e760a193441092571475cc66a3b425f232e
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-Reg_T\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	KRT6A KRT6B KRT16 KRT6C	5.90e-06	198	27	4	3371276410dba693c238b383d990b89371b14d8d
ToppCell	control-Epithelial-Squamous\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	KRT6A KRT6B KRT14 KRT16	6.02e-06	199	27	4	e13dca7a055cdca53dd6c26c04b2a46d58b419b6
ToppCell	Lung_Parenchyma-Severe-Epithelial-Epithelial-Basal_2\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	KRT6A KRT6B KRT16 KRT6C	6.14e-06	200	27	4	c7668e26c6b8cfa6d174b0634e43c230425faba9
ToppCell	distal-Epithelial-Basal\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	KRT6A KRT14 KRT16 KRT6C	6.14e-06	200	27	4	5c14f0c09bb8b3daf6d649032e888a7880c52b73
ToppCell	Lung_Parenchyma-Severe-Epithelial-Epithelial-Basal_2-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	KRT6A KRT6B KRT16 KRT6C	6.14e-06	200	27	4	621dd6438ef6e71811d3644b75209535b7c0f8f7
ToppCell	Parenchyma_COVID-19-Epithelial-TX-Basal_2\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	KRT6A KRT6B KRT16 KRT6C	6.14e-06	200	27	4	bce9bce9eb622bc6514708d49ca4a6604043c22a
ToppCell	droplet-Skin-nan-18m-Epithelial-basal_cell_of_epidermis\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT6A KRT6B KRT16	4.21e-05	112	27	3	32c6ab8e9b71c6c3df7e3e119b88e6ad1b895d50
ToppCell	droplet-Skin-nan-18m-Epithelial-nan\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT6A KRT6B KRT16	5.43e-05	122	27	3	c7e81504e62d132624ec15b7d38dc5b6493a37a4
ToppCell	droplet-Skin-nan-18m-Epithelial\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT6A KRT6B KRT16	5.43e-05	122	27	3	8f675dc341b3f6e22f7e52c34d167d9e37df0982
ToppCell	droplet-Skin-nan-18m\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT6A KRT6B KRT16	5.83e-05	125	27	3	5a309ce803d2b8efd791eb21808121bf5fc3ea8e
ToppCell	droplet-Skin-nan-18m-Epithelial-epidermal_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT6A KRT6B KRT16	6.55e-05	130	27	3	4c8b931987432e8bcd39029d4fa124dc383ea355
ToppCell	facs-Marrow-T-cells-24m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT6A KRT6B KRT16	9.06e-05	145	27	3	4f8b188a93a038afbc7a446df8467ad544f5b1cb
ToppCell	facs-Marrow-T-cells-24m-Myeloid-monocyte_+_promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT6A KRT6B KRT16	1.04e-04	152	27	3	d279592c501fca9cb474ad916fea32282e6969cb
ToppCell	facs-Marrow-T-cells-24m-Myeloid-promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT6A KRT6B KRT16	1.04e-04	152	27	3	3b59143b2b4ee24eb6378f87ff568124193256e9
ToppCell	facs-Marrow-Granulocytes-3m-Lymphocytic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT6A KRT14 KRT16	1.21e-04	160	27	3	8590281165eab6514a9f6a022b900d4c222c1044
ToppCell	TCGA-Skin-Primary_Tumor-Melanoma-Skin_Cutaneous_Melanoma-4\|TCGA-Skin / Sample_Type by Project: Shred V9	KRT14 KRT16 FDX2	1.24e-04	161	27	3	047901a314c079ad19814beca33922a001960ad8
ToppCell	facs-Lung-24m\|Lung / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KRT6A KRT6B KRT16	1.26e-04	162	27	3	4e418bea07e35038b32a78a1e6632b6ec1208cdc
ToppCell	TCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_NOS-4\|TCGA-Stomach / Sample_Type by Project: Shred V9	KRT6A KRT14 KRT6C	1.28e-04	163	27	3	6a12b802cb181f979ebc72674f3626fb855024e3
ToppCell	facs-Lung-Endomucin-24m-Lymphocytic-B_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT6A KRT14 KRT16	1.38e-04	167	27	3	4520ee71e2b119c1dfa0e342fe57eda5f3598650
ToppCell	facs-Marrow-B-cells-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BRINP2 PCDHGB6 PKHD1L1	1.40e-04	168	27	3	17fb9426eeea407b26fb895b8397faca95b7552d
ToppCell	PND07-Epithelial-Epithelial_Airway-Basal-Basal-Basal_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KRT6A KRT6B KRT14	1.40e-04	168	27	3	f150beee37e0252951a88adcd9e3f0a22e5cfdd9
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Myeloid-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT6A KRT14 KRT16	1.40e-04	168	27	3	29a6c3ba69e03ccb19efb8ac177b9a162dc1ea43
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Myeloid\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT6A KRT14 KRT16	1.40e-04	168	27	3	4297be958a4754677df7cf73feba19b0d76f1b4a
ToppCell	facs-Marrow-B-cells-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BRINP2 PCDHGB6 PKHD1L1	1.40e-04	168	27	3	a61b39884851384cffd430079040546d125b2b40
ToppCell	droplet-Skin-nan-18m-Epithelial-keratinocyte_stem_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT6A KRT6B KRT16	1.45e-04	170	27	3	10e0912dd0beab5d0bbe2bd49e477b5962687925
ToppCell	facs-Heart-RV-18m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT6A KRT14 KRT16	1.50e-04	172	27	3	a26a73c41e5a05c9dd47a99f3320295f684c5e54
ToppCell	facs-Marrow-B-cells-24m-Hematologic-hematopoietic_stem_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BRINP2 PLS1 CDH8	1.50e-04	172	27	3	a7fd4d61fb5017dce001d69d6b9a01e6cdf58828
ToppCell	facs-Marrow-B-cells-24m-Hematologic-Unknown_Progenitor\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BRINP2 PLS1 CDH8	1.50e-04	172	27	3	65b8935a972bf00b7a10dc2d442128fc0ed78bcb
ToppCell	facs-Marrow-KLS-18m-Hematologic-Unknown_Progenitor\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BRINP2 MARVELD3 PLS1	1.53e-04	173	27	3	295bfe1efa648173c2d5981025bc61c576baf53f
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Myeloid-macrophage\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT6A KRT14 KRT16	1.55e-04	174	27	3	84f2ffe867f22d2fa79f28737a0aa42bdf2f4804
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KRT6A KRT14 KRT16	1.55e-04	174	27	3	207aa0118633cbe9a65839bbb1bb3ba9f8118ad2
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Epithelial-nan\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT6A KRT6B KRT16	1.58e-04	175	27	3	9a96794df049d8228fea57c1584c160191d36b56
ToppCell	facs-Heart-RV-18m-Myeloid\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT6A KRT14 KRT16	1.58e-04	175	27	3	bde002379088c0407afd0f3dae60b6a166683957
ToppCell	facs-Marrow-Granulocytes-3m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT6A KRT14 KRT16	1.66e-04	178	27	3	6d9ecfaeb50d562899380de379ebf7b99fd8adc9
ToppCell	facs-Marrow-Granulocytes-3m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT6A KRT14 KRT16	1.66e-04	178	27	3	d3f518cd75b02e85d45cbb9b2eff30f0272512a8
ToppCell	TCGA-Head_and_Esophagus-Primary_Tumor-Head_and_Neck_Carcinoma\|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9	KRT6A KRT14 KRT16	1.69e-04	179	27	3	252328c9ce9bf61f741a4ebe170c93733c8747b6
ToppCell	facs-Marrow-T-cells-24m-Hematologic-Unknown_Progenitor\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BRINP2 KRT14 PLS1	1.69e-04	179	27	3	3f2934c5f8816a7b7a6aef8d2f83ebf7b2b693bf
Computational	Keratin.	KRT6A KRT6B KRT14 KRT16	1.57e-07	26	21	4	MODULE_298
Computational	Genes in the cancer module 68.	KRT6A KRT6B KRT14 KRT16	1.57e-07	26	21	4	MODULE_68
Computational	Genes in the cancer module 153.	KRT6A KRT6B KRT14 KRT16	4.81e-07	34	21	4	MODULE_153
Computational	Genes upregulated in subsets of cells of a given type within various tumors	KRT6A KRT6B KRT16 KRT6C	2.34e-06	50	21	4	GAVISH_3CA_METAPROGRAM_EPITHELIAL_EPI3
Computational	Genes upregulated in subsets of cells of a given type within various tumors	KRT6A KRT6B KRT16 KRT6C	2.34e-06	50	21	4	GAVISH_3CA_METAPROGRAM_EPITHELIAL_EPISEN
Computational	Genes upregulated in subsets of cells of a given type within various tumors	KRT6A KRT6B KRT16	1.19e-04	50	21	3	GAVISH_3CA_MALIGNANT_METAPROGRAM_19_EPITHELIAL_SENESCENCE
Computational	Intermediate filaments and MT.	KRT6A KRT6B KRT14	2.97e-04	68	21	3	MODULE_438
Computational	Genes in the cancer module 297.	KRT6A KRT6B KRT14	4.79e-04	80	21	3	MODULE_297
Computational	Intermediate filaments and keratins.	KRT6A KRT6B KRT14	4.79e-04	80	21	3	MODULE_357
Computational	Developmental processes.	KRT6A KRT6B KRT14 KRT16	3.57e-03	333	21	4	MODULE_220
Computational	Genes in the cancer module 325.	BRINP2 UBE2Z	4.72e-03	53	21	2	MODULE_325
Drug	clobestasol propionate	KRT6A KRT6B KRT16 KRT6C	3.69e-09	17	27	4	CID000002791
Drug	dithranol	KRT6A KRT6B KRT16 KRT6C	4.74e-09	18	27	4	CID000002202
Drug	Olux	KRT6A KRT6B KRT16 KRT6C	7.50e-09	20	27	4	CID000032797
Drug	Divonex	KRT6A KRT6B KRT14 KRT16 KRT6C	1.69e-08	69	27	5	CID000002522
Drug	SC-791	KRT6A KRT6B KRT6C	2.97e-08	6	27	3	CID010291510
Drug	phenyl isocyanate	KRT6B KRT14 KRT16	2.97e-08	6	27	3	ctd:C025319
Drug	betamethasone valerate	KRT6A KRT6B KRT16 KRT6C	3.15e-08	28	27	4	CID000016533
Drug	AC1L1KPQ	KRT6A KRT6B KRT14 KRT16 KRT6C	3.15e-08	78	27	5	CID000005602
Drug	plakin	KRT6A KRT6B KRT16 KRT6C DSG1	4.06e-08	82	27	5	CID000018752
Drug	chrysarobin	KRT6A KRT6B KRT14 KRT6C	1.01e-07	37	27	4	CID000068111
Drug	teleocidin B	KRT6A KRT6B KRT14 KRT16 KRT6C	3.11e-07	123	27	5	CID000072425
Drug	mant-GTP	KRT6A KRT6B KRT14 KRT6C	3.48e-07	50	27	4	CID000128647
Drug	sulfur mustard	KRT6A KRT6B KRT14 KRT16 KRT6C	4.10e-07	130	27	5	CID000010461
Drug	homocysteine thiolactone	KRT6A KRT6B KRT14 KRT16 KRT6C	4.26e-07	131	27	5	CID000107712
Drug	cignolin	KRT6A KRT6B KRT16 KRT6C	5.52e-07	56	27	4	CID000010187
Drug	benzalkonium	KRT6A KRT6B KRT14 KRT16 KRT6C	7.80e-07	148	27	5	CID000007681
Drug	1-2q	KRT6A KRT6B KRT14 KRT16 KRT6C DSG1	9.39e-07	289	27	6	CID000011820
Drug	al-Badry	KRT6A KRT6B KRT14 KRT16 KRT6C	1.33e-06	165	27	5	CID000004545
Drug	N1-acetylspermidine	KRT6A KRT6B KRT6C	1.67e-06	20	27	3	CID000000496
Drug	4-hydroxytestosterone	KRT6A KRT6B KRT14 KRT6C	2.11e-06	78	27	4	CID000160615
Drug	AC1L9LMC	KRT6A KRT6B KRT14 KRT6C	2.70e-06	83	27	4	CID000448113
Drug	AC1L9MJT	KRT6A KRT6B KRT14 KRT16 KRT6C	2.81e-06	192	27	5	CID000448959
Drug	MK-6	KRT6A KRT6B KRT6C	2.96e-06	24	27	3	CID005283547
Drug	Bhg-(2-1)fuc	KRT6A KRT6B KRT6C	3.36e-06	25	27	3	CID005287784
Drug	sodium dodecyl sulfate	KRT6A KRT6B KRT16 KRT6C	3.91e-06	91	27	4	CID000008778
Drug	2-Formyl-Protoporphryn Ix	KRT6A KRT6B KRT6C	6.54e-06	31	27	3	CID011963946
Drug	AGN 193109	KRT6A KRT6B KRT6C	6.54e-06	31	27	3	CID000177238
Drug	4,4'-thiodiphenol	KRT6A KRT6B KRT6C	7.21e-06	32	27	3	CID000017570
Drug	M50054	KRT6A KRT6B KRT14 KRT6C	1.06e-05	117	27	4	CID002748618
Drug	tsuwabukinonol	KRT6A KRT6B KRT6C	1.12e-05	37	27	3	CID006440419
Drug	CaLam	KRT6A KRT6B KRT6C	1.32e-05	39	27	3	CID004126474
Drug	PD153035	KRT6A KRT6B KRT14 KRT6C	1.47e-05	127	27	4	CID000004705
Drug	CD-III	KRT6A KRT6B KRT6C	3.35e-05	53	27	3	CID000066693
Drug	DIMIT	KRT6A KRT6B KRT6C	3.95e-05	56	27	3	CID000006624
Drug	CK17	KRT14 KRT16 DSG1	4.17e-05	57	27	3	CID000128831
Drug	Calcein AM	KRT6A KRT6B KRT6C	5.37e-05	62	27	3	CID000390986
Drug	AC1O3H1D	KRT14 KRT16 DSG1	6.77e-05	67	27	3	CID006328166
Drug	Velcade (bortezomib	KRT6A KRT6B KRT14 KRT16 KRT6C	6.98e-05	374	27	5	CID000093860
Drug	bromodeoxyuridine	KRT6A KRT6B KRT16 KRT6C DSG1	7.16e-05	376	27	5	CID000006035
Drug	sulfosuccinimidobiotin	KRT6A KRT6C	8.87e-05	12	27	2	CID000083894
Drug	perylene	APEH PLS1	8.87e-05	12	27	2	CID000009142
Drug	1,4-pentanediamine	KRT6A KRT6B KRT6C	9.49e-05	75	27	3	CID000550880
Drug	Ro 13-6298	KRT14 KRT16	1.05e-04	13	27	2	CID006437076
Drug	AC1L1GT5	KRT14 KRT16 DSG1	1.91e-04	95	27	3	CID000003829
Drug	NSC339663	KRT6A KRT6B KRT14 KRT6C	2.04e-04	250	27	4	CID000003892
Drug	AC1L1JLU	KRT6A KRT6B KRT6C	2.50e-04	104	27	3	CID000005098
Drug	Sudan BB	KRT14 DSG1	3.08e-04	22	27	2	CID005379611
Drug	Lh 1	KRT14 KRT16	3.08e-04	22	27	2	CID000191841
Drug	E-Em	PLS1 CDH8	3.37e-04	23	27	2	CID000021313
Drug	AC1L71LN	KRT6B KRT14 KRT16	4.60e-04	128	27	3	CID000327966
Drug	olomoucine II	KRT14 KRT16	4.67e-04	27	27	2	CID005494414
Drug	Pa-5	APEH KRT14	5.39e-04	29	27	2	CID000191445
Drug	AC1NQZM2	KRT14 KRT16	5.39e-04	29	27	2	CID005282177
Drug	pirfenidone	KRT6A KRT6B KRT6C	5.73e-04	138	27	3	CID000040632
Drug	N-(4-methoxyphenyl)retinamide	KRT6B KRT16	6.17e-04	31	27	2	ctd:C058346
Disease	Pachyonychia congenita syndrome	KRT6A KRT6B KRT16	2.73e-09	4	27	3	cv:C0265334
Disease	Pachyonychia Congenita, Type 2 (disorder)	KRT6A KRT6B KRT16	2.73e-09	4	27	3	C1721007
Disease	Pachyonychia Congenita, Jadassohn Lewandowsky Type	KRT6A KRT6B KRT16	2.73e-09	4	27	3	C1706595
Disease	pachyonychia congenita (is_implicated_in)	KRT6A KRT6B KRT16	2.73e-09	4	27	3	DOID:0050449 (is_implicated_in)
Disease	Pachyonychia Congenita	KRT6A KRT6B KRT16	6.82e-09	5	27	3	C0265334
Disease	Keratoderma, Palmoplantar	KRT14 KRT6C DSG1	3.80e-07	16	27	3	C4551675
Disease	childhood trauma measurement, alcohol consumption measurement	PCDHGB6 PCDHGA11	1.93e-03	71	27	2	EFO_0007878, EFO_0007979
Disease	Squamous cell carcinoma	KRT6B KRT14	5.74e-03	124	27	2	C0007137
Disease	insomnia, total blood protein measurement	KLF15 DSG1	8.08e-03	148	27	2	EFO_0004536, EFO_0004698

Protein segments in the cluster

Peptide	Gene	Start	Entry
GGSLVSSGLGGLSSR	MLLT6	516	P55198
SSTLGGGAGTMGLSA	PCDHGA11	866	Q9Y5H2
SSTLGGGAGTMGLSA	PCDHGB6	861	Q9Y5F9
GGGLSSVGGGSSTIK	KRT6C	536	P48668
GGGLSSVGGGSSTIK	KRT6A	536	P02538
GGGIGGGSSRISSVL	KRT14	21	P02533
GGTSGSGEGVALGTT	FDX2	31	Q6P4F2
GITAIGGTSTISSEG	PLS1	101	Q14651
GGGLSSVGGGSSTIK	KRT6B	536	P04259
GSGTTGPTSAGLGTT	MUC19	2286	Q7Z5P9
RLSVIGSGTTGTSSG	MUC19	2391	Q7Z5P9
SGGLSTTISSVGGTG	MUC19	3001	Q7Z5P9
TTGKALIGSGTTGLS	MUC19	3066	Q7Z5P9
GITGSSPGVTGTTGS	MUC19	3246	Q7Z5P9
AGVTGITGLSAGVTG	MUC19	3531	Q7Z5P9
ITGLSAGVTGTTGLS	MUC19	3536	Q7Z5P9
AGVTGTTGLSTEVTG	MUC19	3541	Q7Z5P9
AGATGTTGLSVGVTG	MUC19	3561	Q7Z5P9
TTGLSVGVTGITGLS	MUC19	3566	Q7Z5P9
GGTGTTGILAGVTGT	MUC19	3641	Q7Z5P9
GVTGTTGLSAGETGK	MUC19	3651	Q7Z5P9
TGLSAGVTGTTGLSP	MUC19	3696	Q7Z5P9
GVTGTTGLSPGVTGT	MUC19	3701	Q7Z5P9
GVTGTTGSLAGGTGT	MUC19	3741	Q7Z5P9
TGSLAGGTGTIGLSA	MUC19	3746	Q7Z5P9
GGTGTIGLSAGVTGT	MUC19	3751	Q7Z5P9
GVTGTTGLSAGVTGI	MUC19	3771	Q7Z5P9
GVTGTTGLSAGVTET	MUC19	3831	Q7Z5P9
GVTGITGLSAGVTGT	MUC19	3861	Q7Z5P9
GVTGTTRSSGGVTGI	MUC19	3911	Q7Z5P9
TRSSGGVTGITGLSA	MUC19	3916	Q7Z5P9
GVTGITGLSAGVTGT	MUC19	3921	Q7Z5P9
GSSTGVTGITGLSAG	MUC19	4046	Q7Z5P9
VTGITGLSAGVTGTT	MUC19	4051	Q7Z5P9
TGTTGLSAGVTGTVG	MUC19	4161	Q7Z5P9
TGTTGLSAGVTGTTG	MUC19	4181	Q7Z5P9
TGITGLSAEVTGTTG	MUC19	4271	Q7Z5P9
TGTTGLSAGVTGITG	MUC19	4281	Q7Z5P9
TRTTGLSAGVTGTIG	MUC19	4301	Q7Z5P9
TGTIGLSAGVTGTTR	MUC19	4311	Q7Z5P9
TGTTVLSAGVTGITG	MUC19	4391	Q7Z5P9
GTTGISAGVTGTTGL	MUC19	4471	Q7Z5P9
GTTGLSAGVTGTIGS	MUC19	4481	Q7Z5P9
GTTGPSAGVTGTTGL	MUC19	4661	Q7Z5P9
GTTGLSAGVTGTAGL	MUC19	4671	Q7Z5P9
GTTGLSAGVTGTTGP	MUC19	4701	Q7Z5P9
GTTGLSAGVTETIGS	MUC19	4881	Q7Z5P9
GTTGLSAGVTGTTGP	MUC19	4921	Q7Z5P9
GTNGLSAGVTGTTGL	MUC19	4941	Q7Z5P9
GTTGLSAGVTGTIGS	MUC19	5021	Q7Z5P9
GTIGSSAVVTGTTGL	MUC19	5031	Q7Z5P9
GTTGLSAGITGTNGL	MUC19	5041	Q7Z5P9
GTTGLSAGVTGTTGL	MUC19	5071	Q7Z5P9
GTTGPSGGVTGTSVL	MUC19	5151	Q7Z5P9
GISGLSGEVTGTTGL	MUC19	5211	Q7Z5P9
GTTGLSAGVTGIGGL	MUC19	5221	Q7Z5P9
SAGVTGIGGLSAGVT	MUC19	5226	Q7Z5P9
GIGGLSAGVTGTIGS	MUC19	5231	Q7Z5P9
GTTGPSAGVTGTTGL	MUC19	5261	Q7Z5P9
GTTGLSAGVTGTTGL	MUC19	5271	Q7Z5P9
GTTGLSAGVTGTIRS	MUC19	5281	Q7Z5P9
GTTGLSAGMTGTTGL	MUC19	5331	Q7Z5P9
GTTGLSTGVTGIAGH	MUC19	5541	Q7Z5P9
GTTTVSAGVTGTIGL	MUC19	5571	Q7Z5P9
GTTGPSAGVTGTTGL	MUC19	5671	Q7Z5P9
GTTGLSAGVTGIAGL	MUC19	5681	Q7Z5P9
GTTGLSAGVTGIAGL	MUC19	5741	Q7Z5P9
GTTGLSAGVTGTTGL	MUC19	5791	Q7Z5P9
GTIGSSAGVKGTTGQ	MUC19	5821	Q7Z5P9
GTTRSSGGVTGITGL	MUC19	5851	Q7Z5P9
AGVTGTIGSSAGVTG	MUC19	5926	Q7Z5P9
TGSGMNTGTTGVVSG	MUC19	7901	Q7Z5P9
GGGIGGGSSRISSVL	KRT16	21	P08779
VSGAGVTGISGTTGI	DSG1	956	Q02413
VTGISGTTGISGGIG	DSG1	961	Q02413
GTTGISGGIGSSGLV	DSG1	966	Q02413
NLTSTLSGGGGGATA	HOXC6	201	P09630
TGTSTGLGTGLGTGL	NUP54	71	Q7Z3B4
GEMGTGGSSSLSTLG	KCNA6	241	P17658
SSTGGYTGITSLGGI	MARVELD3	221	Q96A59
LSQATLGSGGGSGSS	KLF15	81	Q9UIH9
GHSGGLSGTTTLTVT	CDH8	251	P55286
SGIGVGERSSIGSGG	SLC12A8	91	A0AV02
GALGTGIGGITTSTQ	ERVW-1	331	Q9UQF0
GTVTSLTAGGSGGSW	APEH	396	P13798
TETTGGASIIGGSGN	BRINP2	171	Q9C0B6
LGTGSLTGIGTGALG	CNOT1	781	A5YKK6
GSVGGLTGSLSASGS	RNF19A	506	Q9NV58
LSPTSGSIGGGTTLV	PKHD1L1	1836	Q86WI1
GSIGGGTTLVITGNG	PKHD1L1	1841	Q86WI1
GSTAGGTRLTVVGSG	PKHD1L1	2101	Q86WI1
ASSVAGVVGVSGSGG	UBE2Z	21	Q9H832
HGAVTVGGTSVGSLG	ZBTB22	451	O15209