Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	histone H3K9me/H3K9me2 demethylase activity	KDM3B HR	1.89e-05	5	28	2	GO:0140683
GeneOntologyMolecularFunction	histone H3K9 demethylase activity	KDM3B HR	1.71e-04	14	28	2	GO:0032454
GeneOntologyMolecularFunction	histone H3 demethylase activity	KDM3B HR	7.01e-04	28	28	2	GO:0141052
GeneOntologyMolecularFunction	histone demethylase activity	KDM3B HR	8.60e-04	31	28	2	GO:0032452
GeneOntologyMolecularFunction	protein demethylase activity	KDM3B HR	9.16e-04	32	28	2	GO:0140457
GeneOntologyMolecularFunction	nuclear thyroid hormone receptor binding	ARID5A HR	1.03e-03	34	28	2	GO:0046966
GeneOntologyMolecularFunction	chromatin DNA binding	KDM3B REPIN1 HR	1.61e-03	167	28	3	GO:0031490
GeneOntologyMolecularFunction	demethylase activity	KDM3B HR	1.73e-03	44	28	2	GO:0032451
Domain	-	RELN NEU2	2.01e-05	5	27	2	2.120.10.10
Domain	Sialidases	RELN NEU2	7.20e-05	9	27	2	IPR011040
Domain	JmjC	KDM3B HR	5.45e-04	24	27	2	PF02373
Domain	JMJC	KDM3B HR	9.72e-04	32	27	2	PS51184
Domain	JmjC_dom	KDM3B HR	9.72e-04	32	27	2	IPR003347
Domain	JmjC	KDM3B HR	1.03e-03	33	27	2	SM00558
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	KDM3B SHROOM3 INTS5 GRIN2D IDUA ADAMTS7 RGL2 REPIN1 HR	1.28e-07	1105	28	9	35748872
Pubmed	A novel nuclear protein, 5qNCA (LOC51780) is a candidate for the myeloid leukemia tumor suppressor gene on chromosome 5 band q31.	KDM3B HR	6.25e-07	2	28	2	11687974
Pubmed	Ethanol potentiates HIV-1 gp120-induced apoptosis in human neurons via both the death receptor and NMDA receptor pathways.	NLRP1 GRIN2D	5.65e-05	14	28	2	15749123
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	KDM3B SHROOM3 RGL2 NEK9 ARHGEF5	5.63e-04	861	28	5	36931259
Pubmed	Defects During Mecp2 Null Embryonic Cortex Development Precede the Onset of Overt Neurological Symptoms.	RELN GRIN2D	6.06e-04	45	28	2	25979088
Pubmed	Identification of Jmjd3 as an Essential Epigenetic Regulator of Hox Gene Temporal Collinear Activation for Body Axial Patterning in Mice.	KDM3B HR	7.18e-04	49	28	2	34368113
GeneFamily	PDZ domain containing	SHROOM3 FRMPD2	5.98e-03	152	14	2	1220
Coexpression	GSE6269_HEALTHY_VS_E_COLI_INF_PBMC_UP	NLRP1 GAK RGL2 NEK9	3.63e-05	177	28	4	M5641
Coexpression	THAKAR_PBMC_INACTIVATED_INFLUENZA_AGE_21_30YO_RESPONDERS_7DY_DN	MFSD14A NLRP1 GAK IDUA SHFL REPIN1	4.68e-05	634	28	6	M40866
Coexpression	GSE20151_CTRL_VS_FUSOBACT_NUCLEATUM_NEUTROPHIL_DN	KDM3B RGL2 SHFL REPIN1	5.72e-05	199	28	4	M4310
Drug	Famprofazone [22881-35-2]; Up 200; 10.6uM; MCF7; HT_HG-U133A	NEU2 IDUA ADAMTS7 SHFL HR	4.15e-06	200	28	5	6029_UP
Disease	Situs ambiguus	SHROOM3 PKD1L1	7.19e-05	15	25	2	C0266642
Disease	alpha-L-iduronidase measurement	GAK IDUA	9.30e-05	17	25	2	EFO_0020139
Disease	schizophrenia (is_marker_for)	RELN GRIN2D	6.38e-04	44	25	2	DOID:5419 (is_marker_for)
Disease	Moderate albuminuria	SHROOM3 SKIL	2.09e-03	80	25	2	HP_0012594
Disease	cortical thickness	RELN MYEOV SHROOM3 IDUA ADAMTS7	2.14e-03	1113	25	5	EFO_0004840
Disease	ovarian carcinoma	NLRP1 FRMPD2 PKD1L1	2.46e-03	321	25	3	EFO_0001075
Disease	albuminuria	SHROOM3 SKIL	2.87e-03	94	25	2	EFO_0004285
Disease	corneal topography	ADAMTS7 PKD1L1	3.84e-03	109	25	2	EFO_0004345
Disease	creatinine measurement, glomerular filtration rate	SHROOM3 SKIL	4.41e-03	117	25	2	EFO_0004518, EFO_0005208
Disease	triglycerides:total lipids ratio, intermediate density lipoprotein measurement	IRGC SHROOM3	5.17e-03	127	25	2	EFO_0008595, EFO_0020947
Disease	bone mineral content measurement	NLRP1 SKIL	5.41e-03	130	25	2	EFO_0007621

Protein segments in the cluster

Peptide	Gene	Start	Entry
SALRHRLCPASSAWH	ARID5A	561	Q03989
HLHLEKASSWPHRRD	ARHGEF5	996	Q12774
RRCHLRPCATWHSGN	ADAMTS7	1456	Q9UKP4
GRWEHSILCHSPDHT	LRRTM2	331	O43300
SLHHVPDLSCRGWHT	NEK9	706	Q8TD19
HSPHSRLWHSGRCDL	MST1L	91	Q2TV78
SRCHHGLFNTHWRCP	HR	601	O43593
HHHPWEPSVRESLCS	NLRP1	251	Q9C000
LDPHTSHSWLCDGRL	KDM3B	1376	Q7LBC6
CLTLHRHPTPHCSTW	MYEOV	236	Q96EZ4
TWLHTCLAHHDPSLR	IL17C	11	Q9P0M4
TWEHDLPSHRRHAGL	IRGC	231	Q6NXR0
LRSSSWRKHCGSHSH	MFSD14A	456	Q96MC6
NHGRSWSLLHTECLP	RELN	596	P78509
SLPRALHCWDRSLHD	NOTUM	406	Q6P988
CFLSHDHGRTWARGH	NEU2	196	Q9Y3R4
ECGWAARRAPHLHTL	GAK	471	O14976
EPHWSTLTHSHCSLL	FRMPD2	246	Q68DX3
SPLSWGLLRHCHDGT	IDUA	231	P35475
WSSGGPRFHHRRLCA	PKD1L1	146	Q8TDX9
LWGHRDRPGHSHLCP	RGL2	271	O15211
HSHRSPDKRTCHWGF	SKIL	306	P12757
HRRSEPAGRPHSWHT	SHROOM3	151	Q8TF72
LGHWEASRHPDTTHS	INTS5	886	Q6P9B9
AHRCAHCRRHFPGWV	REPIN1	56	Q9BWE0
WDRDPDRRSTHTHSC	SHFL	191	Q9NUL5
SLDTCWGRGPERHVH	ZNF619	51	Q8N2I2
SRHARRCPHAAHWGP	GRIN2D	1291	O15399