Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ATP hydrolysis activity	ABCC3 KIF23 VWA8 MYO19 CHD9 INO80 SRCAP ABCA8 ABCB1 CLPB ATAD2B ATP13A3 DNA2 DNAH8	4.55e-06	441	146	14	GO:0016887
GeneOntologyMolecularFunction	ATP-dependent activity	ABCC3 KIF23 VWA8 MYO7A MYO19 CHD9 INO80 SRCAP ABCA8 ABCB1 ACSL1 CLPB ATAD2B ATP13A3 DNA2 DNAH8	1.13e-05	614	146	16	GO:0140657
GeneOntologyMolecularFunction	dystroglycan binding	CLASP1 DMD VCL	8.03e-05	12	146	3	GO:0002162
GeneOntologyMolecularFunction	cytoskeletal protein binding	TPR KIF23 DCDC1 CLASP1 MYO7A SYNE1 MYO19 SPTAN1 SPTBN2 INO80 TUBGCP4 TUBGCP6 SSH1 MED28 SYNE2 SSH2 DNAI7 DMD TTLL13 VCL	1.50e-04	1099	146	20	GO:0008092
GeneOntologyMolecularFunction	ABC-type xenobiotic transporter activity	ABCC3 ABCA8 ABCB1	1.63e-04	15	146	3	GO:0008559
GeneOntologyMolecularFunction	actin binding	MYO7A SYNE1 MYO19 SPTAN1 SPTBN2 INO80 SSH1 MED28 SYNE2 SSH2 DMD VCL	2.13e-04	479	146	12	GO:0003779
GeneOntologyMolecularFunction	protein-membrane adaptor activity	AKAP6 TPR SYNE1 SYNE2	3.24e-04	45	146	4	GO:0043495
GeneOntologyMolecularFunction	ABC-type transporter activity	ABCC3 ABCA8 ABCB1 ATP13A3	4.50e-04	49	146	4	GO:0140359
GeneOntologyMolecularFunction	cytoskeleton-nuclear membrane anchor activity	SYNE1 SYNE2	5.23e-04	5	146	2	GO:0140444
GeneOntologyBiologicalProcess	spindle assembly	TPR KIF23 CLASP1 INO80 TUBGCP4 SPICE1 TUBGCP6 ASPM	1.16e-05	153	143	8	GO:0051225
GeneOntologyBiologicalProcess	organelle assembly	TPR KIF23 CLASP1 MYO7A SYNE1 SPTBN2 GRB7 SPG11 ODAD4 INO80 TUBGCP4 SPICE1 TUBGCP6 CCDC42 ZMYND10 CEP250 SYNE2 SEC23IP TBC1D14 ASPM DNAH8 IQUB	1.20e-05	1138	143	22	GO:0070925
GeneOntologyBiologicalProcess	microtubule-based process	TPR KIF23 CATSPERE CLASP1 SPG11 APOB ODAD4 INO80 TUBGCP4 SPICE1 TUBGCP6 CCDC42 ZMYND10 CEP250 SYNE2 VPS13A ASPM DNAI7 DNAH8 IQUB TTLL13	1.31e-05	1058	143	21	GO:0007017
Domain	SPEC	AKAP6 SYNE1 SPTAN1 SPTBN2 SYNE2 DMD	1.39e-07	32	143	6	SM00150
Domain	Spectrin/alpha-actinin	AKAP6 SYNE1 SPTAN1 SPTBN2 SYNE2 DMD	1.39e-07	32	143	6	IPR018159
Domain	Spectrin	SYNE1 SPTAN1 SPTBN2 SYNE2 DMD	7.39e-07	23	143	5	PF00435
Domain	Spectrin_repeat	SYNE1 SPTAN1 SPTBN2 SYNE2 DMD	2.51e-06	29	143	5	IPR002017
Domain	ACTININ_2	SYNE1 SPTBN2 SYNE2 DMD	2.61e-05	23	143	4	PS00020
Domain	ACTININ_1	SYNE1 SPTBN2 SYNE2 DMD	2.61e-05	23	143	4	PS00019
Domain	Actinin_actin-bd_CS	SYNE1 SPTBN2 SYNE2 DMD	2.61e-05	23	143	4	IPR001589
Domain	P-loop_NTPase	ABCC3 KIF23 VWA8 MYO7A MTHFD1L MYO19 CHD9 IQCN INO80 SRCAP ABCA8 ABCB1 NWD2 CLPB ATAD2B ASPM DNA2 DNAH8	8.59e-05	848	143	18	IPR027417
Domain	AAA	ABCC3 VWA8 ABCA8 ABCB1 CLPB ATAD2B DNAH8	1.22e-04	144	143	7	SM00382
Domain	AAA+_ATPase	ABCC3 VWA8 ABCA8 ABCB1 CLPB ATAD2B DNAH8	1.22e-04	144	143	7	IPR003593
Domain	CH	SYNE1 SPTBN2 SYNE2 ASPM DMD	1.40e-04	65	143	5	SM00033
Domain	CH	SYNE1 SPTBN2 SYNE2 ASPM DMD	1.99e-04	70	143	5	PF00307
Domain	-	SYNE1 SPTBN2 SYNE2 ASPM DMD	2.13e-04	71	143	5	1.10.418.10
Domain	CH	SYNE1 SPTBN2 SYNE2 ASPM DMD	2.43e-04	73	143	5	PS50021
Domain	CH-domain	SYNE1 SPTBN2 SYNE2 ASPM DMD	2.75e-04	75	143	5	IPR001715
Domain	HEAT_type_2	CLASP1 PPP4R4 MROH1	2.76e-04	17	143	3	IPR021133
Domain	KASH	SYNE1 SYNE2	3.46e-04	4	143	2	IPR012315
Domain	KASH	SYNE1 SYNE2	3.46e-04	4	143	2	PS51049
Domain	DEK_C	SSH1 SSH2	3.46e-04	4	143	2	PF08766
Domain	KASH	SYNE1 SYNE2	3.46e-04	4	143	2	SM01249
Domain	DEK_C	SSH1 SSH2	3.46e-04	4	143	2	IPR014876
Domain	KASH	SYNE1 SYNE2	3.46e-04	4	143	2	PF10541
Domain	Spc97_Spc98	TUBGCP4 TUBGCP6	5.73e-04	5	143	2	PF04130
Domain	GCP	TUBGCP4 TUBGCP6	5.73e-04	5	143	2	IPR007259
Domain	-	ABCC3 VWA8 MYO7A MTHFD1L MYO19 CHD9 INO80 SRCAP ABCA8 ABCB1 NWD2 CLPB ATAD2B DNA2 DNAH8	6.07e-04	746	143	15	3.40.50.300
Domain	IQ	MYO7A MYO19 IQCN ASPM IQUB	7.43e-04	93	143	5	PS50096
Domain	SNF2_N	CHD9 INO80 SRCAP	1.85e-03	32	143	3	IPR000330
Domain	SNF2_N	CHD9 INO80 SRCAP	1.85e-03	32	143	3	PF00176
Domain	HEAT_REPEAT	CLASP1 HEATR1 PPP4R4 MROH1	2.04e-03	70	143	4	PS50077
Domain	IQ	MYO7A MYO19 IQCN ASPM	3.47e-03	81	143	4	SM00015
Domain	ATPase_dyneun-rel_AAA	VWA8 DNAH8	4.99e-03	14	143	2	IPR011704
Domain	TUDOR	TDRD3 TDRD6	4.99e-03	14	143	2	PF00567
Domain	AAA_5	VWA8 DNAH8	4.99e-03	14	143	2	PF07728
Domain	IQ_motif_EF-hand-BS	MYO7A MYO19 IQCN ASPM	5.06e-03	90	143	4	IPR000048
Domain	ABC_tran	ABCC3 ABCA8 ABCB1	5.91e-03	48	143	3	PF00005
Domain	HEAT	CLASP1 HEATR1 MROH1	5.91e-03	48	143	3	PF02985
Domain	ABC_TRANSPORTER_2	ABCC3 ABCA8 ABCB1	5.91e-03	48	143	3	PS50893
Domain	-	POGK GSC2 DNAJC2 HOXC9 SSH1 SSH2 MYBL1	6.20e-03	283	143	7	1.10.10.60
Domain	ABC_TRANSPORTER_1	ABCC3 ABCA8 ABCB1	6.26e-03	49	143	3	PS00211
Domain	ABC_transporter-like	ABCC3 ABCA8 ABCB1	6.62e-03	50	143	3	IPR003439
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	VWA8 TEX2 MTHFD1L SYNE1 SPTAN1 SPTBN2 CCDC18 SPG11 RRP8 HEATR1 NDUFS1 DNAJC2 SPICE1 TUBGCP6 FAM120A CLPB PRCC SYNE2 POP1 VPS13A ASPM PALM PLCH1 DNA2 MTDH VCL	1.17e-09	1487	150	26	33957083
Pubmed	Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.	TEX2 INPP4A SPTAN1 SMG5 INO80 TUBGCP4 DNAJC2 TUBGCP6 TDRD3 NWD2 FAM120A CLPB TRMT1L MTDH	2.15e-08	475	150	14	31040226
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	TTC16 SYNE1 SPTAN1 SPTBN2 SPG11 APOB HEATR1 SRCAP NDUFS1 PPP4R4 ABCB1 CCDC148 MIA2 SYNE2 SEC23IP VPS13A ASPM PALM EEA1 DMD PLCH1 DNAH8 MTDH	6.37e-08	1442	150	23	35575683
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	TPR KIF23 MTHFD1L SPTAN1 SPTBN2 RRP8 PSMD12 HEATR1 NDUFS1 FAM120A ATAD2B SYNE2 POP1 VCL	1.01e-06	653	150	14	22586326
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	KIF23 VWA8 MTHFD1L MYO19 SPTAN1 PSMA5 SPTBN2 RRP8 PSMD12 HEATR1 TUBGCP4 NDUFS1 ANKRD13A FAM120A CLPB SYNE2 POP1 ATP13A3 TRMT1L MTDH ALPI	1.08e-06	1440	150	21	30833792
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	TPR KIF23 CLASP1 SPTAN1 PSMA5 SIN3A IQCN RPRD1B SPICE1 TUBGCP6 STK10 TBC1D4 SSH1 POP1 ALPI	1.43e-06	774	150	15	15302935
Pubmed	Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy.	DCDC1 CLASP1 SYNE1 SPTAN1 SYNE2 SSH2 DMD DNAH8	1.65e-06	187	150	8	26460568
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	VWA8 TEX2 MTHFD1L SYNE1 MYO19 PSMA5 MRPL54 RRP8 HEATR1 LARP1B NDUFS1 TDRD3 FAM120A MIA2 CLPB SYNE2 SEC23IP VPS13A MRPL34 PRAME MTDH	1.97e-06	1496	150	21	32877691
Pubmed	Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.	TPR ABCC3 KIF23 INPP4A SPG11 EXT1 HEATR1 NDUFS1 PPP4R4 RPRD1B ACSL1 TP53TG5 UBE2T CLPB ASPM ATP13A3 SSH2 CLSPN RBM18	4.78e-06	1327	150	19	32694731
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	TPR SYNE1 CEP250 POP1 ASPM EEA1 DMD PLCH1	8.62e-06	234	150	8	36243803
Pubmed	Quantitative Assessment of the Association between ABC Polymorphisms and Osteosarcoma Response: a Meta-analysis.	ABCC3 ABCB1	1.85e-05	2	150	2	26107220
Pubmed	Effect of ABCB1 and ABCC3 polymorphisms on osteosarcoma survival after chemotherapy: a pharmacogenetic study.	ABCC3 ABCB1	1.85e-05	2	150	2	22016816
Pubmed	Nesprins: a novel family of spectrin-repeat-containing proteins that localize to the nuclear membrane in multiple tissues.	SYNE1 SYNE2	1.85e-05	2	150	2	11792814
Pubmed	Nesprin-1 and nesprin-2 regulate endothelial cell shape and migration.	SYNE1 SYNE2	1.85e-05	2	150	2	24931616
Pubmed	Cancer-related SRCAP and TPR mutations in colon cancers.	TPR SRCAP	1.85e-05	2	150	2	33307343
Pubmed	Genetics of alkaline phosphatase of the small intestine of the house mouser (Mus musculus).	IDH1 ALPI	1.85e-05	2	150	2	6626138
Pubmed	Multiple novel nesprin-1 and nesprin-2 variants act as versatile tissue-specific intracellular scaffolds.	SYNE1 SYNE2	1.85e-05	2	150	2	22768332
Pubmed	Modulation of MDR1 and MRP3 gene expression in lung cancer cells after paclitaxel and carboplatin exposure.	ABCC3 ABCB1	1.85e-05	2	150	2	23443122
Pubmed	Molecular mechanism of chemoresistance by astrocyte elevated gene-1.	ABCB1 MTDH	1.85e-05	2	150	2	20388796
Pubmed	Characterization of a new beta-spectrin gene which is predominantly expressed in brain.	SPTAN1 SPTBN2	1.85e-05	2	150	2	9675416
Pubmed	Syne-1 and Syne-2 play crucial roles in myonuclear anchorage and motor neuron innervation.	SYNE1 SYNE2	1.85e-05	2	150	2	17267447
Pubmed	Nesprins: tissue-specific expression of epsilon and other short isoforms.	SYNE1 SYNE2	1.85e-05	2	150	2	24718612
Pubmed	Targeted ablation of nesprin 1 and nesprin 2 from murine myocardium results in cardiomyopathy, altered nuclear morphology and inhibition of the biomechanical gene response.	SYNE1 SYNE2	1.85e-05	2	150	2	24586179
Pubmed	Effect of variation of ABCB1 and ABCC3 genotypes on the survival of bone tumor cases after chemotherapy.	ABCC3 ABCB1	1.85e-05	2	150	2	24083708
Pubmed	Nesprin-1 and -2 are involved in the pathogenesis of Emery Dreifuss muscular dystrophy and are critical for nuclear envelope integrity.	SYNE1 SYNE2	1.85e-05	2	150	2	17761684
Pubmed	Nesprin-1-alpha2 associates with kinesin at myotube outer nuclear membranes, but is restricted to neuromuscular junction nuclei in adult muscle.	SYNE1 SYNE2	1.85e-05	2	150	2	31578382
Pubmed	Purification and assay of the human INO80 and SRCAP chromatin remodeling complexes.	INO80 SRCAP	1.85e-05	2	150	2	17101442
Pubmed	alphaII-betaV spectrin bridges the plasma membrane and cortical lattice in the lateral wall of the auditory outer hair cells.	MYO7A SPTAN1 SPTBN2	2.18e-05	13	150	3	18796539
Pubmed	HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.	VWA8 TEX2 MTHFD1L SYNE1 SPTAN1 LENG1 APOB PSMD12 HEATR1 CLPB SYNE2 DMD MTDH	2.54e-05	754	150	13	35906200
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	POGK MYO19 GRB7 SIN3A TUBGCP4 DENND3 FAM120A PRCC POP1 PLCH1 CLSPN DNA2	2.72e-05	650	150	12	38777146
Pubmed	Interactomes of Glycogen Synthase Kinase-3 Isoforms.	CLASP1 TEX2 LARP1B TDRD3 TBC1D4 FAM120A VCL	3.64e-05	209	150	7	36779422
Pubmed	Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods.	CLASP1 TUBGCP4 SPICE1 TUBGCP6 CEP250 LRRCC1	4.30e-05	146	150	6	21399614
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	TPR KIF23 MTHFD1L SYNE1 SPTAN1 PSMA5 APOB PSMD12 HEATR1 NDUFS1 RPRD1B FAM120A CLPB SEC23IP EEA1 TDRD6 MTDH VCL	4.53e-05	1425	150	18	30948266
Pubmed	Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.	KIF23 COL12A1 MTHFD1L SPTAN1 APOB PSMD12 NDUFS1 RPRD1B TDRD3 TBC1D4 FAM120A SYNE2 POP1 MRPL34 TRMT1L EEA1 ALPI	4.75e-05	1297	150	17	33545068
Pubmed	BS69 undergoes SUMO modification and plays an inhibitory role in muscle and neuronal differentiation.	ZMYND11 UBE2I	5.53e-05	3	150	2	19766626
Pubmed	TANGO1 and Mia2/cTAGE5 (TALI) cooperate to export bulky pre-chylomicrons/VLDLs from the endoplasmic reticulum.	APOB MIA2	5.53e-05	3	150	2	27138255
Pubmed	Vectorial transport of fexofenadine across Caco-2 cells: involvement of apical uptake and basolateral efflux transporters.	ABCC3 ABCB1	5.53e-05	3	150	2	21780830
Pubmed	Differential activities, subcellular distribution and tissue expression patterns of three members of Slingshot family phosphatases that dephosphorylate cofilin.	SSH1 SSH2	5.53e-05	3	150	2	14531860
Pubmed	The inner nuclear membrane protein Sun1 mediates the anchorage of Nesprin-2 to the nuclear envelope.	SYNE1 SYNE2	5.53e-05	3	150	2	16079285
Pubmed	Genotype Phenotype Correlation and Variability in Microcephaly Associated With Chorioretinopathy or Familial Exudative Vitreoretinopathy.	TUBGCP4 TUBGCP6	5.53e-05	3	150	2	33137195
Pubmed	Fxr1 knockout mice show a striated muscle phenotype: implications for Fxr1p function in vivo.	DMD VCL	5.53e-05	3	150	2	15128702
Pubmed	Combination analysis of three polymorphisms for predicting the risk for steroid-induced osteonecrosis of the femoral head.	APOB ABCB1	5.53e-05	3	150	2	18696186
Pubmed	[Expression of ATP-binding Cassette Proteins Pgp, MRP1, and MRP3 in Malignant and Benign Ovarian Lesions].	ABCC3 ABCB1	5.53e-05	3	150	2	27739315
Pubmed	Syne-1, a dystrophin- and Klarsicht-related protein associated with synaptic nuclei at the neuromuscular junction.	SYNE1 SYNE2	5.53e-05	3	150	2	10878022
Pubmed	Predictive potential of ABCB1, ABCC3, and GSTP1 gene polymorphisms on osteosarcoma survival after chemotherapy.	ABCC3 ABCB1	5.53e-05	3	150	2	24996541
Pubmed	The nesprins are giant actin-binding proteins, orthologous to Drosophila melanogaster muscle protein MSP-300.	SYNE1 SYNE2	5.53e-05	3	150	2	12408964
Pubmed	MRP3, BCRP, and P-glycoprotein activities are prognostic factors in adult acute myeloid leukemia.	ABCC3 ABCB1	5.53e-05	3	150	2	16278398
Pubmed	Distinct functional domains in nesprin-1alpha and nesprin-2beta bind directly to emerin and both interactions are disrupted in X-linked Emery-Dreifuss muscular dystrophy.	SYNE1 SYNE2	5.53e-05	3	150	2	17462627
Pubmed	Expression analysis of MDR1, BCRP and MRP3 transporter proteins in different in vitro and ex vivo cornea models for drug absorption studies.	ABCC3 ABCB1	5.53e-05	3	150	2	23069916
Pubmed	Archvillin, a muscle-specific isoform of supervillin, is an early expressed component of the costameric membrane skeleton.	DMD VCL	5.53e-05	3	150	2	12711699
Pubmed	[Genetic analysis for prevention of steroid-induced osteonecrosis of the femoral head].	APOB ABCB1	5.53e-05	3	150	2	17548929
Pubmed	Structures of FHOD1-Nesprin1/2 complexes reveal alternate binding modes for the FH3 domain of formins.	SYNE1 SYNE2	5.53e-05	3	150	2	33472039
Pubmed	Nesprins anchor kinesin-1 motors to the nucleus to drive nuclear distribution in muscle cells.	SYNE1 SYNE2	5.53e-05	3	150	2	25516977
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SPTBN2 ABCA8 DENND3 PPP4R4 FAM120A SSH1 POP1 LRRCC1 SSH2 PLCH1	5.97e-05	493	150	10	15368895
Pubmed	SARS-CoV-2 uses Spike glycoprotein to control the host's anaerobic metabolism by inhibiting LDHB.	TPR MTHFD1L SPTAN1 GRB7 PSMD12 IDH1 RPRD1B CLPB EEA1 MTDH VCL	7.00e-05	607	150	11	39147351
Pubmed	Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	TEX2 SYNE1 IQCN LRRCC1 SSH2	8.30e-05	102	150	5	11214970
Pubmed	Centrosome-related genes, genetic variation, and risk of breast cancer.	KIF23 CLASP1 TUBGCP4 CEP250 ASPM	8.30e-05	102	150	5	20508983
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	KIF23 CLASP1 TEX2 SPG11 PSMD12 NDUFS1 TDRD3 FAM120A SEC23IP PLCH1 CLSPN VCL	8.58e-05	733	150	12	34672954
Pubmed	A protein interaction landscape of breast cancer.	TPR VWA8 MYO19 SPTBN2 LENG1 FADD SMG5 IDH1 TRMT1L MTDH SENP5	1.03e-04	634	150	11	34591612
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	TPR ANKRD35 KIF23 SPTAN1 PSMA5 CHD9 PSMD12 IDH1 TUBGCP4 NDUFS1 SPICE1 TBC1D4 FAM120A POP1 TRMT1L VCL	1.03e-04	1247	150	16	27684187
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	ZMYND11 DCDC1 VWA8 POGK CHD9 SIN3A INO80 SRCAP ABCA8 TUBGCP6 FAM120A ASPM CLSPN DNA2 TENT2	1.03e-04	1116	150	15	31753913
Pubmed	SUN1 interacts with nuclear lamin A and cytoplasmic nesprins to provide a physical connection between the nuclear lamina and the cytoskeleton.	SYNE1 SYNE2	1.10e-04	4	150	2	16648470
Pubmed	The slingshot family of phosphatases mediates Rac1 regulation of cofilin phosphorylation, laminin-332 organization, and motility behavior of keratinocytes.	SSH1 SSH2	1.10e-04	4	150	2	17848544
Pubmed	Regulation of mRNA expression of MDR1, MRP1, MRP2 and MRP3 by prototypical microsomal enzyme inducers in primary cultures of human and rat hepatocytes.	ABCC3 ABCB1	1.10e-04	4	150	2	16946557
Pubmed	Loss of β2-spectrin prevents cardiomyocyte differentiation and heart development.	SPTBN2 DMD	1.10e-04	4	150	2	24064296
Pubmed	Outer nuclear membrane protein Kuduk modulates the LINC complex and nuclear envelope architecture.	SYNE1 SYNE2	1.10e-04	4	150	2	28716842
Pubmed	The Organic Anion-Transporting Peptide 2B1 Is Localized in the Basolateral Membrane of the Human Jejunum and Caco-2 Monolayers.	ABCC3 ABCB1	1.10e-04	4	150	2	28408210
Pubmed	Polymorphisms of the drug transporters ABCB1, ABCG2, ABCC2 and ABCC3 and their impact on drug bioavailability and clinical relevance.	ABCC3 ABCB1	1.10e-04	4	150	2	25162314
Pubmed	LINC complexes mediate the positioning of cone photoreceptor nuclei in mouse retina.	SYNE1 SYNE2	1.10e-04	4	150	2	23071752
Pubmed	Nesprins, but not sun proteins, switch isoforms at the nuclear envelope during muscle development.	SYNE1 SYNE2	1.10e-04	4	150	2	20108321
Pubmed	Distinct expression of type XIII collagen in neuronal structures and other tissues during mouse development.	COL13A1 VCL	1.10e-04	4	150	2	11470398
Pubmed	Inhibition of tetramethylpyrazine on P-gp, MRP2, MRP3 and MRP5 in multidrug resistant human hepatocellular carcinoma cells.	ABCC3 ABCB1	1.10e-04	4	150	2	19956884
Pubmed	Nesprin-2 interacts with meckelin and mediates ciliogenesis via remodelling of the actin cytoskeleton.	SYNE1 SYNE2	1.10e-04	4	150	2	19596800
Pubmed	Impact of genetic variants of ABCB1, APOB, CAV1, and NAMPT on susceptibility to pancreatic ductal adenocarcinoma in Chinese patients.	APOB ABCB1	1.10e-04	4	150	2	32243098
Pubmed	Systematic analysis of human protein complexes identifies chromosome segregation proteins.	TPR KIF23 CLASP1 POGK SYNE1 TUBGCP4 SPICE1 TUBGCP6 FAM120A UBE2I POP1 ASPM EEA1 VCL MYBL1	1.50e-04	1155	150	15	20360068
Pubmed	GCP5 and GCP6: two new members of the human gamma-tubulin complex.	TUBGCP4 TUBGCP6	1.83e-04	5	150	2	11694571
Pubmed	Role of dystrophins and utrophins in platelet adhesion process.	DMD VCL	1.83e-04	5	150	2	16803572
Pubmed	LINC complexes form by binding of three KASH peptides to domain interfaces of trimeric SUN proteins.	SYNE1 SYNE2	1.83e-04	5	150	2	22632968
Pubmed	Structural requirements for the assembly of LINC complexes and their function in cellular mechanical stiffness.	SYNE1 SYNE2	1.83e-04	5	150	2	18396275
Pubmed	Efflux protein expression in human stem cell-derived retinal pigment epithelial cells.	ABCC3 ABCB1	1.83e-04	5	150	2	22272278
Pubmed	Mutational analysis of mononucleotide repeats in dual specificity tyrosine phosphatase genes in gastric and colon carcinomas with microsatellite instability.	SSH1 SSH2	1.83e-04	5	150	2	20477815
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	SPTAN1 SPTBN2 CCDC18 PSMD12 PPP4R4 SPICE1 TDRD3 TBC1D4 SSH1 SYNE2 VPS13A PALM SSH2 DMD	1.90e-04	1049	150	14	27880917
Pubmed	Centrosomal proteins CG-NAP and kendrin provide microtubule nucleation sites by anchoring gamma-tubulin ring complex.	CLASP1 TUBGCP4 TUBGCP6 CEP250	1.95e-04	66	150	4	12221128
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	CLASP1 MYO7A MYO19 PSMD12 HEATR1 TUBGCP4 NDUFS1 ACSL1 ANKRD13A TBC1D4 ZMYND10 PRCC SEC23IP EEA1 PRAME VCL	1.98e-04	1321	150	16	27173435
Pubmed	Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.	COL13A1 SYNE1 SPTAN1 PSMA5 PSMD12 IQCN IDH1 SRCAP SLC13A4 POP1 EEA1 VCL	2.09e-04	807	150	12	30575818
Pubmed	Replication of a genome-wide case-control study of esophageal squamous cell carcinoma.	SYNE1 DNAH8 FLACC1	2.13e-04	27	150	3	18649358
Pubmed	Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.	CLASP1 MTHFD1L PSMA5 SPG11 APOB EXT1 PSMD12 IDH1 MROH1 SEC23IP VPS13A PALM ATP13A3 EEA1	2.13e-04	1061	150	14	33845483
Pubmed	A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.	KIF23 CLASP1 PSMD12 HEATR1 DNAJC2 STK10 PRCC ASPM TRMT1L	2.22e-04	472	150	9	38943005
Pubmed	The protein network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1.	SYNE1 SPTAN1 CLPB SYNE2 TDRD6 DMD	2.23e-04	197	150	6	20811636
Pubmed	WWP1 upregulation predicts poor prognosis and promotes tumor progression by regulating ubiquitination of NDFIP1 in intrahepatic cholangiocarcinoma.	TUBGCP4 TUBGCP6 FAM120A MCTP2	2.31e-04	69	150	4	35264565
Pubmed	Interaction of Daxx, a Fas binding protein, with sentrin and Ubc9.	FADD UBE2I	2.74e-04	6	150	2	11112409
Pubmed	ST3GAL1 and βII-spectrin pathways control CAR T cell migration to target tumors.	SPTAN1 SPTBN2	2.74e-04	6	150	2	37069398
Pubmed	Control of actin reorganization by Slingshot, a family of phosphatases that dephosphorylate ADF/cofilin.	SSH1 SSH2	2.74e-04	6	150	2	11832213
Pubmed	Structural Analysis of Different LINC Complexes Reveals Distinct Binding Modes.	SYNE1 SYNE2	2.74e-04	6	150	2	33058875
Pubmed	TorsinA binds the KASH domain of nesprins and participates in linkage between nuclear envelope and cytoskeleton.	SYNE1 SYNE2	2.74e-04	6	150	2	18827015
Pubmed	Parathyroid hormone mediates hematopoietic cell expansion through interleukin-6.	PTH VCL	2.74e-04	6	150	2	21048959
Pubmed	Phospholipase Cε hydrolyzes perinuclear phosphatidylinositol 4-phosphate to regulate cardiac hypertrophy.	AKAP6 PLCH1	2.74e-04	6	150	2	23540699
Pubmed	Chromosomal assignment of three novel mouse genes expressed in testicular cells.	TEX2 IDH1	2.74e-04	6	150	2	8088835
Pubmed	In vivo assembly of the axon initial segment in motor neurons.	SPTAN1 SPTBN2	2.74e-04	6	150	2	23728480
Pubmed	Spectrins and ankyrinB constitute a specialized paranodal cytoskeleton.	SPTAN1 SPTBN2	2.74e-04	6	150	2	16687515
GeneFamily	Slingshot protein phosphatases	SSH1 SSH2	8.52e-05	3	97	2	898
GeneFamily	Spectrin repeat containing nuclear envelope family	SYNE1 SYNE2	1.70e-04	4	97	2	1252
GeneFamily	EF-hand domain containing\|Spectrins	SPTAN1 SPTBN2	5.88e-04	7	97	2	1113
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	ZMYND11 KIF23 CLASP1 CHD9 SPG11 EXT1 DNAJC2 STK10 TDRD3 FCHSD2 MIA2 ATAD2B SYNE2 VPS13A ATP13A3 DMD VCL MYBL1	2.10e-06	856	150	18	M4500
Coexpression	GSE27786_CD8_TCELL_VS_NKCELL_UP	AKAP6 TPR MTHFD1L NTHL1 PSMD12 HEATR1 FCHSD2 DNAH8 PDE11A	2.31e-06	199	150	9	M4836
Coexpression	GSE3982_DC_VS_NKCELL_DN	AKAP6 SYNE1 SPTBN2 SH2D3C SYNE2 MCTP2 SEC14L5 MYBL1	1.87e-05	197	150	8	M5480
CoexpressionAtlas	dev gonad_e13.5_F_MeioticGermCell_Oct_top-relative-expression-ranked_1000	KIF23 TEX2 STRA8 CCDC18 HEATR1 LARP1B TUBGCP4 ZNF235 PPP4R4 SPICE1 ACSL1 NEK3 UBE2T VPS13A SSH2 CLSPN DNA2 DNAH8 MYBL1	3.28e-06	820	145	19	gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_1000
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	AKAP6 DCDC1 ANKUB1 SYNE1 ODAD4 SYNE2 DNAI7 DMD FLACC1 IQUB	1.42e-09	197	150	10	74a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCell	COPD-Myeloid-cMonocyte\|COPD / Disease state, Lineage and Cell class	EXT1 ACSL1 FAM157C TBC1D14 HRH2 FAM157A ATP13A3 MCTP2	2.64e-07	189	150	8	d29f3a0bd23e6eb46389e6eb7ef21851c7b57545
ToppCell	IPF-Epithelial-Ciliated\|Epithelial / Disease state, Lineage and Cell class	AKAP6 DCDC1 SYNE1 ODAD4 ZMYND10 DNAI7 DMD PLCH1	3.10e-07	193	150	8	ad58f5080e0ba65c845056ea6b79037b636e9c64
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC3 TRABD2B DCDC1 TAS1R3 STRA8 RYR3 SYNE2	1.43e-06	164	150	7	1cb5fbd7050650047ad6f2ca792118e98d58d22b
ToppCell	lung-Ciliated_Epithelia\|lung / shred on tissue and cell subclass	DCDC1 TTC16 ODAD4 ZMYND10 DNAI7 FLACC1 IQUB	1.61e-06	167	150	7	26cf1cfa58ee74794449a87eb19cd896e1ec8892
ToppCell	PND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD4_T-CD4_T_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CCDC18 NEK3 UBE2T ASPM CLSPN DNAH8 MYBL1	1.61e-06	167	150	7	754e6412d3b9cc0b126e59593df2f5956b4712ef
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	KIF23 CCDC18 UBE2T ZMYND10 ASPM DNA2 MYBL1	1.75e-06	169	150	7	b253a4a50c06d36228fcd5d856c57202cbac158f
ToppCell	droplet-Thymus-nan-24m-Lymphocytic-DN_to_DP_transition_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination__)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TTC16 POGK MYO19 STRA8 DENND3 PNCK MCTP2	1.89e-06	171	150	7	d1e87478d8c0329e662849823f5c7604f20e1b1a
ToppCell	367C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	KIF23 CCDC18 UBE2T ASPM IL1RL1 CLSPN MYBL1	1.89e-06	171	150	7	e3cab55f39879e2bd3e8bda91802181075839bc4
ToppCell	367C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	KIF23 CCDC18 UBE2T ASPM IL1RL1 CLSPN MYBL1	1.89e-06	171	150	7	52fdc2a4ec36fb91583b1215362548ceb6740ae1
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c08-IL2RB\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	MYO7A SYNE1 ZSCAN9 CHD9 ABCB1 MCTP2 MYBL1	1.96e-06	172	150	7	e3a8891694343b6b01e80a200ae338d24797e417
ToppCell	facs-Trachea-24m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l28\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ANKRD35 NTHL1 CCDC18 RRP8 SPICE1 TUBGCP6 FCHSD2	2.20e-06	175	150	7	aa168aeb9ad71aa6c0c28a0657c9eb92a0b28183
ToppCell	facs-Skin-Anagen-24m-Epithelial-actively_dividing_stem_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF23 MYO7A UBE2T ASPM DNAH8 TTLL13 MYBL1	2.37e-06	177	150	7	8a0f0fbb06cdacb99a3fdba0da3e0494b891db4f
ToppCell	facs-Skin-Anagen-24m-Epithelial-keratinocyte_stem_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF23 MYO7A UBE2T ASPM DNAH8 TTLL13 MYBL1	2.37e-06	177	150	7	e9d7682517fb30fd2ad535d59779d718a7024c13
ToppCell	facs-Marrow-Granulocytes-18m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF23 SYNE1 LARP1B ACSL1 SYNE2 ASPM VCL	2.46e-06	178	150	7	15a99080e9f669572ab6d82934f324e6714846c1
ToppCell	facs-Marrow-Granulocytes-18m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF23 SYNE1 LARP1B ACSL1 SYNE2 ASPM VCL	2.46e-06	178	150	7	200308e109abb7e6f8816a6f8cce6d56862d4098
ToppCell	COVID-19_Mild-gd_T\|COVID-19_Mild / Disease condition and Cell class	TTC16 SYNE1 ABCB1 STK10 SYNE2 VCL MYBL1	2.96e-06	183	150	7	f593a89b0aa8fffdfa403769916facfd30358521
ToppCell	COPD-Myeloid-cMonocyte\|World / Disease state, Lineage and Cell class	EXT1 ACSL1 FAM157C HRH2 FAM157A ATP13A3 MCTP2	3.07e-06	184	150	7	ceec41ed5636032aaf7716d1203816ea58bd39bd
ToppCell	Control-T_cells-NK_cells\|Control / group, cell type (main and fine annotations)	CLASP1 INPP4A ABCB1 STK10 TMC8 MCTP2 MYBL1	3.18e-06	185	150	7	755c0998c729f462399f1d5e88adf4bfae31be30
ToppCell	facs-Skin-Telogen-3m-Epithelial-actively_dividing_stem_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF23 UBE2T ASPM PLCH1 CLSPN DNAH8 MYBL1	3.29e-06	186	150	7	9feef5936985e936b3d88f9d1bb012abb6468570
ToppCell	facs-Skin-Telogen-3m-Epithelial-keratinocyte_stem_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF23 UBE2T ASPM PLCH1 CLSPN DNAH8 MYBL1	3.29e-06	186	150	7	89f5b06bc56674af304912d481ac697c7c870904
ToppCell	LA-13._Vascular_Smooth_Muscle\|LA / Chamber and Cluster_Paper	AKAP6 MTHFD1L EXT1 RYR3 PLD5 DMD VCL	3.54e-06	188	150	7	34e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCell	COPD-Multiplet-Multiplet\|World / Disease state, Lineage and Cell class	SYNE1 SYNE2 ASPM IL1RL1 CLSPN MCTP2 MYBL1	3.54e-06	188	150	7	186fe1ea328c942910190a4240262c0d8642ea3b
ToppCell	COVID-19-T_cells-NK_cells\|COVID-19 / group, cell type (main and fine annotations)	SYNE1 ABCB1 STK10 SYNE2 TMC8 MCTP2 MYBL1	3.66e-06	189	150	7	b699152dfbb8cd8ed724e1e5a51838f29b681b62
ToppCell	Nasal_Brush-Epithelial-Ciliated_2\|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X	DCDC1 ANKUB1 SYNE1 ODAD4 ZMYND10 DNAI7 IQUB	3.79e-06	190	150	7	9ce7df056bfb24d70db4c3c4a2c57d89115de877
ToppCell	5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.4.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TTC16 SYNE1 SYNE2 TMC8 SSH2 MCTP2 MYBL1	3.79e-06	190	150	7	d153a0bdedcd6865e6ee19575234a78b5d859ff1
ToppCell	Nasal_Brush-Epithelial-Ciliated_2\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	DCDC1 ANKUB1 SYNE1 ODAD4 ZMYND10 DNAI7 IQUB	3.79e-06	190	150	7	833481ace2800354712e2ce709d5cdfd0aed3d42
ToppCell	Bronchial_Biopsy-Epithelial-Ciliated_1\|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X	DCDC1 ANKUB1 SYNE1 ODAD4 ZMYND10 DNAI7 IQUB	4.06e-06	192	150	7	be592e661367affced9ebe80849b466e6adb3a34
ToppCell	droplet-Skin-nan-21m-Epithelial-stem_cell_of_epidermis\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF23 CCDC18 UBE2T ASPM CLSPN DNAH8 MYBL1	4.06e-06	192	150	7	96f23d6e8604d1cb24910d3118d8171b57c93e14
ToppCell	Control-Myeloid-cMonocyte\|Control / Disease state, Lineage and Cell class	EXT1 ACSL1 FAM157C HRH2 FAM157A ATP13A3 MCTP2	4.06e-06	192	150	7	ad04c9c4bdebf94615cee1904ca48197e62c923b
ToppCell	Bronchial_Biopsy-Epithelial-Ciliated_1\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	DCDC1 ANKUB1 SYNE1 ODAD4 ZMYND10 DNAI7 IQUB	4.20e-06	193	150	7	0b62a6ddd7c42efd9f39781971d1438501e1fa8d
ToppCell	Control-Myeloid-cMonocyte\|World / Disease state, Lineage and Cell class	ACSL1 STK10 FAM157C HRH2 FAM157A ATP13A3 MCTP2	4.35e-06	194	150	7	f852f5258617a66a4fbd56d64c7b47272e7b8b60
ToppCell	Control-Lymphoid-pDC\|Lymphoid / Condition, Lineage and Cell class	SPIB TEX2 NEK3 FCHSD2 HRH2 DMD VCL	4.35e-06	194	150	7	5f95a5a35f73222dbe2ca52cc580f4774f641403
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c05-ZNF683\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	ANKRD35 TTC16 SYNE1 ABCB1 SYNE2 CLSPN MYBL1	4.35e-06	194	150	7	24837a27b0041fe8c348225fa8b09b127d743603
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC3 DCDC1 SYNE1 TBC1D4 SYNE2 SSH2 PLCH1	4.35e-06	194	150	7	e577d9e88390b36b5a09b97fe1026089892275a3
ToppCell	Bronchial_Brush-Epithelial-Ciliated_1\|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X	DCDC1 ANKUB1 SYNE1 ODAD4 ZMYND10 DNAI7 IQUB	4.35e-06	194	150	7	b4ce60c06568123008b1081d644733cb91c28f51
ToppCell	COVID-19-lung-NK_cells\|COVID-19 / Disease (COVID-19 only), tissue and cell type	TTC16 STK10 SYNE2 DEF6 TMC8 MCTP2 MYBL1	4.35e-06	194	150	7	4c92f18e0a34fb50630d4b260eaf179202508b6d
ToppCell	Bronchial_Brush-Epithelial-Ciliated_1\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	DCDC1 ANKUB1 SYNE1 ODAD4 ZMYND10 DNAI7 IQUB	4.35e-06	194	150	7	7a7ddccfe72a4a0dc4d1a5c809988f0069f9f1a3
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	AKAP6 DCDC1 ANKUB1 SYNE1 ODAD4 DNAI7 IQUB	4.35e-06	194	150	7	4a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCell	Control-Myeloid-ncMonocyte\|World / Disease state, Lineage and Cell class	SH2D3C EXT1 DENND3 ACSL1 STK10 FAM157C FAM157A	4.50e-06	195	150	7	b4444b67a709e82b8e2ee510924c3152cb88b051
ToppCell	COPD-Multiplet-Multiplet\|COPD / Disease state, Lineage and Cell class	DCDC1 SYNE1 SYNE2 ASPM PLCH1 CLSPN MCTP2	4.65e-06	196	150	7	af4cdc61830685a888a1209826c23bcf54a43084
ToppCell	COPD-Multiplet\|COPD / Disease state, Lineage and Cell class	DCDC1 SYNE1 SYNE2 ASPM PLCH1 CLSPN MCTP2	4.65e-06	196	150	7	6d02d494196e3f857d53eea46d9419690d43beca
ToppCell	COVID-19_Severe-NK\|World / disease group, cell group and cell class	COL13A1 SYNE1 ABCB1 SYNE2 KIR3DL3 MCTP2 MYBL1	4.65e-06	196	150	7	f46ca7cc2d8407d0dcaa77c4b16a2c1f2a23734d
ToppCell	COVID_non-vent-Lymphocytic-T_cell-CD8+_Memory_T_cell\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	TTC16 SYNE1 SPG11 STK10 SYNE2 TMC8 MYBL1	4.81e-06	197	150	7	836061acd7f0d5de89b16f52ec679bdf09eac9db
ToppCell	PSB-critical-LOC-Epithelial-Ciliated\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DCDC1 ANKUB1 SYNE1 DNAI7 PLCH1 FLACC1 IQUB	4.81e-06	197	150	7	6865f4831eb23794fb88a8649d48d497bbae3f44
ToppCell	Parenchymal-10x3prime_v2-Epithelial-Epi_airway_ciliated-Deuterosomal\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	KIF23 DCDC1 ODAD4 SLC13A4 UBE2T ASPM DNAI7	4.81e-06	197	150	7	861e8df9bd74dc5e17bafdc1fb3fef546753c73a
ToppCell	T_cells-CTLs\|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis	TTC16 SYNE1 SPG11 STK10 SYNE2 VCL MYBL1	4.81e-06	197	150	7	28117cf300e169182571fbad0de1681a484a435a
ToppCell	LPS_only-Epithelial_airway-airway_epithelial-Ciliated\|LPS_only / Treatment groups by lineage, cell group, cell type	MYO7A TTC16 ODAD4 CCDC148 SLC13A4 ZMYND10 PLCH1	4.97e-06	198	150	7	6d90b541fde357fbb40f8f7d4e8628a48b679718
ToppCell	(09)_Interm._secr.>cil.-(2)_GFP_FOXI1\|(09)_Interm._secr.>cil. / shred by cell type by condition	TPR ZMYND11 PSMA5 PSMD12 FAM120A SYNE2 EEA1	5.14e-06	199	150	7	fc680f85ebd3bab4c72876a19a461b0afb5f51ce
ToppCell	LPS_IL1RA-Endothelial-Endothelial-FOXM1\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	KIF23 CCDC18 UBE2T SYNE2 ASPM CLSPN MYBL1	5.14e-06	199	150	7	be2276c9a1994579ba1d2998b49bf549c1324d44
ToppCell	(01)_IL1RL1+-(2)_GFP_FOXI1\|(01)_IL1RL1+ / shred by cell type by condition	TPR PSMA5 PSMD12 FAM120A SYNE2 EEA1 VCL	5.14e-06	199	150	7	a2f7d0cabf35b80fe239fae34a77bf9344d5d743
ToppCell	Bronchus_Control_(B.)-Epithelial-TX-Ciliated\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	DCDC1 ANKUB1 SYNE1 ODAD4 ZMYND10 DNAI7 IQUB	5.31e-06	200	150	7	6a2ccc71a0cbe04a542c379b28b5006de53981c3
ToppCell	Lung_Parenchyma-Control-Epithelial-Epithelial-Ciliated\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	DCDC1 TTC16 ANKUB1 ODAD4 ZMYND10 DNAI7 IQUB	5.31e-06	200	150	7	ddd39b754bfaa98249d497dfb7e97ec58617a11a
ToppCell	Parenchyma_Control_(B.)-Epithelial-TX-Ciliated\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	DCDC1 TTC16 ANKUB1 ODAD4 ZMYND10 DNAI7 IQUB	5.31e-06	200	150	7	a521cf837cadf280505ff9d7e641a205af7d6513
ToppCell	Lung_Parenchyma-Control-Epithelial-Epithelial-Ciliated-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	DCDC1 TTC16 ANKUB1 ODAD4 ZMYND10 DNAI7 IQUB	5.31e-06	200	150	7	918b576fd9491d23c2bb9d663fa5fb3505cb1c7e
ToppCell	COVID-19-COVID-19_Severe-Lymphocyte-T/NK-gd_T\|COVID-19_Severe / Disease, condition lineage and cell class	TTC16 INPP4A SYNE1 ABCB1 STK10 SYNE2 MYBL1	5.31e-06	200	150	7	f72bc3f6606ae77fe1b0a972e35b3ce0727804d9
ToppCell	(24)_B_cell_cycling\|World / shred on Cell_type and subtype	KIF23 ZNF695 UBE2T ASPM DMD CLSPN DNA2	5.67e-06	202	150	7	a7c9b6b173701348ba35fbb975e0bdd3c1f1d5fe
ToppCell	facs-MAT-Fat-24m-Lymphocytic-NK_cell\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DNAJC2 CCDC148 NEK3 CEP250 TMC8 MYBL1	1.29e-05	152	150	6	fa03262e2853b7d35ef8cdbb652930abad90563c
ToppCell	Globus_pallidus-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocyte.Tnr.Cyth3_(Cyth3)-\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	MYO19 SPG11 SIN3A TUBGCP4 STK10 TRMT1L	1.34e-05	153	150	6	553dff9688a1996d8f4ba16e60c683593d781389
ToppCell	Globus_pallidus-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocyte.Tnr.Cyth3_(Cyth3)\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	MYO19 SPG11 SIN3A TUBGCP4 STK10 TRMT1L	1.34e-05	153	150	6	88ca2d2c2ab19fbee13e18951b993ee05dd30f67
ToppCell	Control-Epithelial_airway-Ciliated_cells-Ciliated\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TTC16 ANKUB1 ODAD4 CCDC148 ZMYND10 FLACC1	1.39e-05	154	150	6	4e3bc24043144143842627cacf6f90dda2228910
ToppCell	Control-Epithelial_airway-Ciliated_cells\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TTC16 ANKUB1 ODAD4 CCDC148 ZMYND10 FLACC1	1.39e-05	154	150	6	7556a4b2b062da5ae7ec2bbb66e745e7662db628
ToppCell	COVID-19_Moderate-multiplets\|World / disease group, cell group and cell class	ENOX1 TTC16 SYNE1 SYNE2 TMC8 MYBL1	1.50e-05	156	150	6	afdc025fa75e7926b1cc182c4a33654a2186abb1
ToppCell	facs-Trachea-nan-3m-Myeloid-lymphocyte_of_B_lineage\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF23 SPIB PRND ASPM MCTP2 DNAH8	1.55e-05	157	150	6	0fecc14959c4c9efc19d5c06475a890e0a30f148
ToppCell	390C-Lymphocytic-CD4_T-cell-Proliferating_T_cell\|390C / Donor, Lineage, Cell class and subclass (all cells)	KIF23 MYRFL UBE2T CCDC42 ASPM KEL	1.67e-05	159	150	6	0fbfdb18b7ed4bde077add13f2b3636e144b254f
ToppCell	PND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_G2M\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KIF23 SPIB CCDC18 UBE2T ASPM CLSPN	1.98e-05	164	150	6	249d8f75a64bce7db52ce0c563f496b9edf602a6
ToppCell	367C-Lymphocytic-CD4_T-cell-Proliferating_T_cell\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	KIF23 ZNF695 UBE2T ASPM KEL CLSPN	1.98e-05	164	150	6	fb18b863152fb3109e2224c791c84c6371680a4e
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c07-TYROBP\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	SYNE1 RRP8 C3orf49 ABCA8 SYNE2 MYBL1	2.20e-05	167	150	6	ded4d6cccd3660662f12cf5a512de31d26325f1b
ToppCell	droplet-Lung-nan-18m-Myeloid-Plasmacytoid_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPIB TEX2 INPP4A STRA8 PNCK MCTP2	2.43e-05	170	150	6	749144a1a869a6bf9acdd227184319083367dc3f
ToppCell	droplet-Lung-nan-18m-Myeloid-plasmacytoid_dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPIB TEX2 INPP4A STRA8 PNCK MCTP2	2.43e-05	170	150	6	25d60a62e8f99c31ab64fe6a0c07ccca3df1a7ee
ToppCell	Globus_pallidus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Col15a1_(Col15a1)-\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	COL12A1 COL13A1 TAS1R3 SLC13A4 SEC14L5	2.47e-05	102	150	5	0bbc6344d0baee47326a16a89773bb5c68a7b040
ToppCell	Globus_pallidus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Col15a1_(Col15a1)\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	COL12A1 COL13A1 TAS1R3 SLC13A4 SEC14L5	2.47e-05	102	150	5	11fbdb428824023603e9d4ee41e957ba84e7c29e
ToppCell	droplet-Lung-18m-Hematologic-myeloid-plasmacytoid_dendritic_cell-plasmacytoid_dendritic\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SPIB TEX2 INPP4A STRA8 PNCK MCTP2	2.59e-05	172	150	6	422d311bba2dd5d8bece4e96ee8c86e78086b62d
ToppCell	E18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-PMP-PMP_G2M\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KIF23 COL12A1 COL13A1 UBE2T ASPM CLSPN	2.59e-05	172	150	6	c06ca5d075937747952ed915c9db39a9f62072f9
ToppCell	CTRL-Myeloid-Neutrophil\|CTRL / Disease state, Lineage and Cell class	DENND3 ACSL1 SYNE2 HRH2 FAM157A MCTP2	2.59e-05	172	150	6	ef3a6fe3b7300959f9f71130200c7fb8741c42b0
ToppCell	droplet-Lung-18m-Hematologic-myeloid-plasmacytoid_dendritic_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SPIB TEX2 INPP4A STRA8 PNCK MCTP2	2.59e-05	172	150	6	1abb6fbb28c8aff384540493d0f70eeacaa751f4
ToppCell	droplet-Lung-nan-3m-Myeloid-plasmacytoid_dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPIB TEX2 MYO19 STRA8 PNCK MCTP2	2.68e-05	173	150	6	1b9b4e165121b08ef15a93fca6bea875cae69f19
ToppCell	droplet-Lung-nan-3m-Myeloid-Plasmacytoid_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPIB TEX2 MYO19 STRA8 PNCK MCTP2	2.68e-05	173	150	6	c25f24d7b672c9686d31ebc8d263042282f520fd
ToppCell	Club-club-15\|World / Class top	KIF23 ZNF235 CCDC148 UBE2T ASPM CLSPN	2.86e-05	175	150	6	ca9d012f520f697c7450ec6958a015e20538a6a8
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_NK-T_mait-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	SYNE1 GRB7 ABCB1 SYNE2 IL1RL1 MYBL1	2.86e-05	175	150	6	cc2428150987911d0d382e8177918724aa69f85c
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c07-TYROBP\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	SYNE1 CHD9 DENND3 ABCB1 MCTP2 MYBL1	2.86e-05	175	150	6	8fb8c4b9e2d9b7d737f59cd9bd3dc2bca5a8dfc4
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_B-B_cell-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	AKAP6 SPIB CHD9 IQCN RPRD1B FAM157A	2.86e-05	175	150	6	69ed3c7c45df6bef70f5f2ff003531160bf3b32b
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_NK-T_mait\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	SYNE1 GRB7 ABCB1 SYNE2 IL1RL1 MYBL1	2.95e-05	176	150	6	003076f1a983409ddf31b9c19e61c1facdd72566
ToppCell	facs-Trachea-3m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell-ciliated_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ANKUB1 ODAD4 CCDC148 ZMYND10 PLCH1 IQUB	3.05e-05	177	150	6	3cfde67b93f3986312f5e74e42504214d966e7dc
ToppCell	facs-Trachea-3m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ANKUB1 ODAD4 CCDC148 ZMYND10 PLCH1 IQUB	3.05e-05	177	150	6	12a52a12a87a31e501ced611f46a90d172ca7e35
ToppCell	droplet-Marrow-nan-3m-Lymphocytic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPIB TEX2 CHD9 TBC1D4 PNCK MCTP2	3.25e-05	179	150	6	dcaf2191134a586d50ebaf67dcf5b815b54a722b
ToppCell	droplet-Marrow-nan-3m-Lymphocytic-nan\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPIB TEX2 CHD9 TBC1D4 PNCK MCTP2	3.25e-05	179	150	6	87a69f9f83b8f0c028a4874acb238f2e079bf51f
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KIF23 NEK3 UBE2T ASPM CLSPN MYBL1	3.35e-05	180	150	6	5e1680088065be14447d5d5465f91f7edd071a1e
ToppCell	facs-Trachea-nan-3m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANKUB1 ODAD4 CCDC148 ZMYND10 PLCH1 IQUB	3.35e-05	180	150	6	cf6e9f757afeb342c5023f6e6152a1b4d0d164b4
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CCDC18 UBE2T ASPM CLSPN DNA2 MYBL1	3.35e-05	180	150	6	401df9cddcbca1eb8f0d2687bcacd98e95dc1493
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF23 SYNE1 LARP1B ACSL1 SYNE2 VCL	3.45e-05	181	150	6	566249e04dd491e6287ad2101b7b1ab11031ed8b
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF23 SYNE1 LARP1B ACSL1 SYNE2 VCL	3.45e-05	181	150	6	db9528dc7cb0230e4c36cb27da69102c588c7ee9
ToppCell	Adult-Epithelial-ciliated_cell-D122\|Adult / Lineage, Cell type, age group and donor	ENOX1 DCDC1 TTC16 ODAD4 ZMYND10 DNAI7	3.56e-05	182	150	6	7ded554a4b441e6496db673ba206c0d76ccad7d9
ToppCell	NS-moderate-d_16-33-Epithelial-Ciliated\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	AKAP6 DCDC1 ANKUB1 DNAI7 FLACC1 IQUB	3.90e-05	185	150	6	5e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCell	Control-T_cells-Cycling_NK/T_cells\|Control / group, cell type (main and fine annotations)	KIF23 CCDC18 ASPM CLSPN DNA2 MYBL1	3.90e-05	185	150	6	9766216b41ee62bbac4caa25cb98ec5627a24075
ToppCell	(05)_Ciliated-(3)_72hpi\|(05)_Ciliated / shred by cell type and Timepoint	CCDC18 DENND3 UBE2T ASPM DNAH8	4.05e-05	113	150	5	eaa5bc8f8183b353ee1e7618e99220eb3684cd60
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	SYNE1 ZNF688 SSH1 SYNE2 MYBL1 SENP5	4.14e-05	187	150	6	b426a67b5669019115b58295ce7d304beeb75825
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRABD2B KIF23 CCDC148 SYNE2 MCTP2 VCL	4.27e-05	188	150	6	af740fa78542438fdff627ea1f74f4eee43316be
ToppCell	COPD-Myeloid-cMonocyte\|Myeloid / Disease state, Lineage and Cell class	EXT1 FAM157C HRH2 FAM157A ATP13A3 MCTP2	4.40e-05	189	150	6	6294691231c7d38707323cf31578a107d3b2c622
ToppCell	LA-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	AKAP6 MTHFD1L EXT1 RYR3 PLD5 DMD	4.40e-05	189	150	6	6b3e88751b95fc2173f2c3d5061ed632d0c5f01c
Drug	tiapamil	SYNE1 ABCB1 DMD	5.31e-06	6	148	3	CID000042106
Drug	prostaglandin E2; Down 200; 10uM; PC3; HT_HG-U133A	COL13A1 SYNE1 DENND3 NEK3 CEP250 DEF6 SEC23IP PALM EEA1	5.89e-06	197	148	9	6547_DN
Disease	Colorectal Carcinoma	AKAP6 ABCC3 MTHFD1L NTHL1 SYNE1 SPTBN2 APOB IDH1 ABCA8 ABCB1 HOXC9 VPS13A DMD DNAH8 MTDH IQUB	4.39e-07	702	146	16	C0009402
Disease	Microcephaly and chorioretinopathy	TUBGCP4 TUBGCP6	7.27e-05	3	146	2	cv:CN263236
Disease	Autosomal recessive chorioretinopathy-microcephaly syndrome	TUBGCP4 TUBGCP6	7.27e-05	3	146	2	cv:C3502492
Disease	Microcephaly with Chorioretinopathy, Autosomal Recessive	TUBGCP4 TUBGCP6	7.27e-05	3	146	2	C3502492
Disease	Autosomal dominant Emery-Dreifuss muscular dystrophy	SYNE1 SYNE2	1.45e-04	4	146	2	cv:CN293514
Disease	Autosomal Recessive Emery-Dreifuss Muscular Dystrophy	SYNE1 SYNE2	2.41e-04	5	146	2	C1450051
Disease	Autosomal Dominant Emery-Dreifuss Muscular Dystrophy (disorder)	SYNE1 SYNE2	2.41e-04	5	146	2	C0410190
Disease	Emery-Dreifuss muscular dystrophy	SYNE1 SYNE2	3.60e-04	6	146	2	cv:C0410189
Disease	Muscular Dystrophy, Emery-Dreifuss	SYNE1 SYNE2	3.60e-04	6	146	2	C0410189
Disease	X-Linked Emery-Dreifuss Muscular Dystrophy	SYNE1 SYNE2	5.02e-04	7	146	2	C0751337
Disease	familial hyperlipidemia (is_implicated_in)	APOB ABCB1	6.68e-04	8	146	2	DOID:1168 (is_implicated_in)
Disease	Neoplasm Metastasis	FADD ABCB1 MED28 HRH2 DMD MTDH	7.61e-04	217	146	6	C0027627
Disease	Malignant neoplasm of breast	AKAP6 CATSPERE SYNE1 SPTAN1 GRB7 ABCB1 MIA2 MED28 SYNE2 POP1 DMD CLSPN MTDH FLACC1	9.22e-04	1074	146	14	C0006142
Disease	Arthritis, Collagen-Induced	ABCB1 ACSL1 IL1RL1	1.03e-03	40	146	3	C0971858
Disease	Arthritis, Experimental	ABCB1 ACSL1 IL1RL1	1.03e-03	40	146	3	C0993582
Disease	Arthritis, Adjuvant-Induced	ABCB1 ACSL1 IL1RL1	1.03e-03	40	146	3	C0003865
Disease	Emery-Dreifuss muscular dystrophy (implicated_via_orthology)	SYNE1 SYNE2	1.55e-03	12	146	2	DOID:11726 (implicated_via_orthology)
Disease	Hematologic Neoplasms	IDH1 ABCB1	1.55e-03	12	146	2	C0376545
Disease	end stage renal disease (biomarker_via_orthology)	ABCC3 PTH ABCB1	1.64e-03	47	146	3	DOID:783 (biomarker_via_orthology)
Disease	acute myeloid leukemia (is_marker_for)	ABCC3 FADD PRAME	1.85e-03	49	146	3	DOID:9119 (is_marker_for)
Disease	vision disorder	TRABD2B CCDC42	2.79e-03	16	146	2	MONDO_0021084
Disease	Post-Traumatic Osteoporosis	PSMA5 PTH VCL	3.46e-03	61	146	3	C0751406
Disease	Osteoporosis, Senile	PSMA5 PTH VCL	3.46e-03	61	146	3	C0029459
Disease	Osteoporosis, Age-Related	PSMA5 PTH VCL	3.46e-03	61	146	3	C0001787
Disease	Osteoporosis	PSMA5 PTH VCL	3.79e-03	63	146	3	C0029456
Disease	Sarcomatoid Renal Cell Carcinoma	GRB7 PRCC SYNE2 PRAME	3.82e-03	128	146	4	C1266043
Disease	Chromophobe Renal Cell Carcinoma	GRB7 PRCC SYNE2 PRAME	3.82e-03	128	146	4	C1266042
Disease	Collecting Duct Carcinoma of the Kidney	GRB7 PRCC SYNE2 PRAME	3.82e-03	128	146	4	C1266044
Disease	Papillary Renal Cell Carcinoma	GRB7 PRCC SYNE2 PRAME	3.82e-03	128	146	4	C1306837
Disease	Renal Cell Carcinoma	GRB7 PRCC SYNE2 PRAME	3.82e-03	128	146	4	C0007134
Disease	coagulation factor measurement	ENOX1 ASPM	4.36e-03	20	146	2	EFO_0004634
Disease	common carotid intimal medial thickness	APOB EXT1 RYR3	4.51e-03	67	146	3	EFO_0004860
Disease	nose morphology measurement, mouth morphology measurement	DNA2 TTLL13	4.80e-03	21	146	2	EFO_0007843, EFO_0007955
Disease	mean platelet volume	TEX2 CHD9 SIN3A SRCAP ACSL1 TBC1D4 SSH1 ATAD2B SYNE2 TBC1D14 ATP13A3 SEC14L5	4.87e-03	1020	146	12	EFO_0004584

Protein segments in the cluster

Peptide	Gene	Start	Entry
DLKAKVRQWRAHQEE	CCDC148	366	Q8NFR7
KINTRDAVKLHLWTN	CATSPERE	521	Q5SY80
IRNNSLWDRLIFHKV	ACSL1	406	P33121
KLTWHKVQNISRDAI	ATP13A3	696	Q9H7F0
EHVKRALQKDEQLRW	H2AL3	81	A0A3B3IU63
EKEKQSRQRLTKWNH	ANKRD36BP1	101	Q96IX9
SWHRLKNKRDLNSIL	TENT2	461	Q6PIY7
DKALWRHLQQALSRR	ANKRD35	231	Q8N283
EKLNLHSADWQRKID	DMD	2916	P11532
RWAHIQNTAAKKTLL	CCDC42	241	Q96M95
KEGRAHRRSWQQKLN	DENND3	341	A2RUS2
QWKTRQLQSKLHEAD	MTHFD1L	251	Q6UB35
KERQKLRNSCKTWNH	DNAJC2	351	Q99543
WHLRKQAKEENSAII	ASPM	1456	Q8IZT6
RDKWPHSLRVQKLDT	ADAT1	451	Q9BUB4
ERHVKNVTLLVWANR	NWD2	721	Q9ULI1
SKKLVVRWAHAQVKR	RBM18	96	Q96H35
TGRKNQEQWHVVSRK	NPFFR2	356	Q9Y5X5
QLQHLKSKALRERWL	PALM	41	O75781
KAIQEAWRRFNKRHI	IQCN	131	Q9H0B3
NPHDRKVIRRFWSQK	INO80	601	Q9ULG1
VHARKNKNVDILWQA	INPP4A	866	Q96PE3
LLEAWRKQEKQTARH	ABCC3	256	O15438
WCLAAGRQIHKIRKQ	ABCB1	136	P08183
LRHKADVTKENRQGW	ANKRD13A	61	Q8IZ07
SARNWQKLSQRHKLQ	DCDC1	156	M0R2J8
NPVANWIHARSTRKK	HOXC9	181	P31274
LQEVRHWLEKNFSKR	DIO2	251	Q92813
RAHQALVIWKTQSNK	LRRD1	806	A4D1F6
LNLVVKQGDFKRHRW	MCTP2	311	Q6DN12
KTKEVPWRRDQINRH	FLACC1	311	Q96Q35
QAAIRSWLTRKHIQR	MYO19	791	Q96H55
KKSWHVRNKDNVARV	LENG1	6	Q96BZ8
KARKHILQIHTRDWN	ATAD2B	576	Q9ULI0
SLWPRKQKRRKTEQH	FAM157A	96	C9JC47
NRSKWEELHQKRLLA	PDE11A	901	Q9HCR9
NVAHSKLLKNWRDLD	DNAH8	206	Q96JB1
FLLHRWCANKKNAVV	KIR3DL3	341	Q8N743
DQAKRINHISSWKAA	HRH2	211	P25021
LWPRKQKRRKTEQHS	FAM157C	101	P0CG43
HQRRWSEDKSKSVLA	MYRFL	736	Q96LU7
KSNQTDAIKWRLRNH	TUBGCP4	506	Q9UGJ1
QKALWRIQRHRLESA	TUBGCP6	776	Q96RT7
DALVQKHLTKLRHWQ	MED28	126	Q9H204
EKARLHEWVKRQGNE	FAM120A	101	Q9NZB2
KTLIDKARVETQNHW	PSMA5	86	P28066
WKDLKNRVVEHNIRI	PSMD12	351	O00232
VRDWRKVKPQLQNAH	POGK	231	Q9P215
VLFHQWLQSREAKLR	MROH1	226	Q8NDA8
LEEAQAWRKKTNHRL	GRB7	396	Q14451
RKASSPNLHRRQWEK	NEK3	351	P51956
EQIRKNFARTHWKRA	PNCK	286	Q6P2M8
WNRQAAEALDAAKKL	ALPI	31	P09923
EFNRRQKKNIWLETH	POP1	191	Q99575
SLQIKHTQALNRKWA	EEA1	1336	Q15075
TKNQKIRWKNEVRIH	APOB	3626	P04114
WRCVIIDEAHRLKNK	CHD9	991	Q3L8U1
KWREDHIANKRSLNS	IL1RL1	511	Q01638
WTRGLAHRAKLDNNK	IDH1	336	O75874
NRRAKWRHQKRASAS	GSC2	176	O15499
ERWHRAVSTNLLKQN	C3orf49	41	Q96BT1
QDRIFKHISRNSLIW	EXT1	431	Q16394
WQLNAHRDKKSLLQA	COL12A1	1251	Q99715
RNWELKQRAAQVTHL	CCDC18	1016	Q5T9S5
HKLHQDLWKTQQTRD	CEP250	1246	Q9BV73
RIWKNTEKENATVAH	FADD	146	Q13158
WANLKKNPRHRSVRF	DNAI7	216	Q6TDU7
RKLRQASTNVKHWNV	DEF6	531	Q9H4E7
AWETKISHREKRQQR	MTDH	191	Q86UE4
QWHAKIFVENLRRQK	IQUB	351	Q8NA54
FWAKRAKQRHNITLL	CLPB	586	Q9H078
AKQRHNITLLWDREV	CLPB	591	Q9H078
RVIQLLKINNSKHRW	HEATR1	146	Q9H583
LWKREQARLKAHVVD	ENDOV	16	Q8N8Q3
RVNQLLDEKWKLHSR	COL13A1	91	Q5TAT6
EHSLNKEARKWATRV	FCHSD2	321	O94868
DWRRLNVAITRAKHK	DNA2	996	P51530
AAAVEKWNLHKRIAL	SLC13A4	96	Q9UKG4
RQSLSWRKQHQVDLL	SEC14L5	286	O43304
SKAQRKNIDIWRKHS	ENOX1	366	Q8TC92
KNIDIWRKHSEELRN	ENOX1	371	Q8TC92
RERWHNHLNPEVKKS	MYBL1	126	P10243
SSNQRKRANKHKWVP	LARP1B	66	Q659C4
WRGQKKRRIANTHLN	KIF23	281	Q02241
KKAHDNWLAARNAER	MIA2	1066	Q96PC5
FHKRQEATRSLLQAW	TSGA10IP	376	Q3SY00
KLRRHLQNLHWKVSV	TRMT1L	136	Q7Z2T5
VSVWHRELRKAKSNR	RPRD1B	41	Q9NQG5
EKWELQRSLSKHNRS	TDRD3	66	Q9H7E2
VKNPSEFWIRLRKHN	TDRD6	496	O60522
EQRAAASLKWRTHEK	PPP4R4	491	Q6NUP7
ASVWLRRKDKLEHSQ	PLD5	51	Q8N7P1
RWKLQVLDLRKNSHQ	PRAME	116	P78395
IHQAKERELELKNTW	PRCC	461	Q92733
ERHKLKRQDADAWTL	SMG5	931	Q9UPR3
TWFETQEKRLKQQHR	SYNE1	7036	Q8NF91
DHRNLRKWLTNQEEK	SYNE2	1951	Q8WXH0
WLASAKNRRQKAHVT	SYNE2	6676	Q8WXH0
ARIRKSWLHNDLKVA	NDUFS1	416	P28331
HVHRIANRLRWTKKA	NTHL1	241	P78549
QEKWLRDHKRRPSQT	ODAD4	256	Q96NG3
RVSKRLHQRFQAWVD	SIN3A	1201	Q96ST3
KKAVTTNQWHRRLEF	SEC23IP	371	Q9Y6Y8
SSKHKELLARRWGQQ	SPIB	201	Q01892
KLVLQDHQAFRRKNW	SRCAP	726	Q6ZRS2
WRRQLDKNLRFHKLV	NOX3	91	Q9HBY0
HKSKNRALVHWELQE	SPICE1	56	Q8N0Z3
ERKASLRQAWAQKHR	STRA8	191	Q7Z7C7
ILDASKQRHNKLWRQ	SSH1	446	Q8WYL5
KQRHNKLWRQQTDSS	SSH1	451	Q8WYL5
SRHQVWNLLKERKTD	ABCA8	651	O94911
SQWKELQRQIKRQHS	AKAP6	866	Q13023
IKQWILRAQSHSLHK	ANKUB1	316	A6NFN9
RELEALKQRFWKHAN	CLSPN	526	Q9HAW4
HDWEQRVNALKKIRS	CLASP1	336	Q7Z460
NRRIQELHKLAKRCW	TP53TG5	56	Q9Y2B4
KHIEQWSLKQARIDF	SPG11	1716	Q96JI7
RKQSARLDKHNDLGW	TBC1D14	246	Q9P2M4
RKAQRSWVQKVTGDH	SENP5	261	Q96HI0
ERLKIRWHTSDNQKP	TAS1R3	481	Q7RTX0
GKQWDKNSNKRHLRV	nan	181	Q6ZTK2
NARAIHRLRKQLVWQ	TMC8	621	Q8IU68
RKEPWNVNTEKTARH	ZNF695	71	Q8IW36
NWREARKLSVSTQHI	VPS13A	726	Q96RL7
LSRLAQERKAWRKDH	UBE2I	6	P63279
LIKRHEAFQKSAVAW	SPTBN2	2051	O15020
LLASKQRHNKLWRSH	SSH2	446	Q76I76
LRKQNIWRHNRLSKN	MRPL54	121	Q6P161
DVKRWKARNQHLVSQ	TPR	1331	P12270
SQLEEFGRQRKWHKR	TRABD2B	416	A6NFA1
LAENAHNVWAKDRIK	RYR3	986	Q15413
HWKELKQLAAARGQR	SPTAN1	1851	Q13813
HRIKWNRKALPSTAQ	PRND	31	Q9UKY0
HNQNLKEWRDKLRPR	STK10	906	O94804
AARQLHDEARKWSSK	VCL	901	P18206
KNARQWTEKHARQKQ	UBE2T	141	Q9NPD8
SNIKRKNKHGWVRRL	MRPL34	56	Q9BQ48
HTLSRKQWRNRQKNK	RRP8	181	O43159
SKELRSLWRKAIHQQ	TBC1D4	836	O60343
LAKRQRTHDQWVKQT	PLCH1	136	Q4KWH8
KRKFAVEAHQWIHRS	ZNF688	221	P0C7X2
KRRQADTKAIQHLWA	ZMYND11	6	Q15326
CRWRNQALHFKINKV	SH2D3C	256	Q8N5H7
ERQKALALQHSWKQG	TTC16	531	Q8NEE8
LERENRGKWQAIAKH	ZMYND10	341	O75800
KVEAKSHLQWQESRL	ZSCAN9	26	O15535
RVEWLRKKLQDVHNF	PTH	51	P01270
KLHKNLRHWNTRSLD	TEX2	526	Q8IWB9
LQAKGKERQWLRHQA	VWA8	1661	A3KMH1
WQIKRHIASKLARSQ	ZNF235	106	Q14590
CRQKASLNWHQRKHA	ZNF692	426	Q9BU19
KRKLSTLNIWLQEHS	TTLL13	311	A6NNM8
KNRLRRILEVQNSWH	KEL	126	P23276
SKHALIWAQRKENES	LRRCC1	671	Q9C099
KLKNAATLIQRHWRG	MYO7A	766	Q13402