Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
CoexpressionLIAN_NEUTROPHIL_GRANULE_CONSTITUENTS

MMP13 MAN2C1

2.44e-052582M1478
CoexpressionLIAN_NEUTROPHIL_GRANULE_CONSTITUENTS

MMP13 MAN2C1

2.64e-052682MM639
CoexpressionMORI_MATURE_B_LYMPHOCYTE_DN

RNASEH2B DESI1

2.30e-047682M15847
CoexpressionMORI_MATURE_B_LYMPHOCYTE_DN

RNASEH2B DESI1

2.74e-048382MM596
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Fam19a1_Tmem182|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SLC9A4 DOCK10

2.09e-0412482690595d710b57b7cff8029a3bb06a8dd7e3c03c1
ToppCellLPS_only-Epithelial_airway-Ciliated_cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SLC9A4 CCDC180

3.22e-041548258072ce422d09f2de602580325eaac6c4ec6c136
ToppCellLPS_only-Epithelial_airway-Ciliated_cells-Ciliated|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SLC9A4 CCDC180

3.22e-04154829ca71d440c4f87781e6525b8141e7d8d470b6a8e
ToppCellLPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SLC9A4 CCDC180

3.26e-04155825f1e2195a6b831e1b636f5cc3a282ca423721822
ToppCellLPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells-Ciliated|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SLC9A4 CCDC180

3.26e-04155820944429459f642a1bcc56edc1ec28aaecde3e2dc
ToppCellPND07-28-samps-Myeloid-Macrophage-macrophage-B|PND07-28-samps / Age Group, Lineage, Cell class and subclass

SLC9A4 DOCK10

3.47e-0416082694bf1f1952bd8ab444819f533da24fa2b73f701
ToppCellLPS-IL1RA+antiTNF-Epithelial_airway|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SLC9A4 CCDC180

3.64e-0416482e4d4c59aebe5cacd4ecdb907facd044dc82a831d
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Proliferating-cycling_ventral_progenitors|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

SLC9A4 RNASEH2B

3.92e-041708273601c873b177d5d134618d8e228c51381119f7d
ToppCellfacs-Lung-EPCAM-18m-Myeloid-Myeloid_Dendritic_Type_2|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC9A4 DOCK10

4.24e-04177823cb96d7d56c9ff90f1f8a6caaf49e580e2524c7d
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-4M-Neuronal-ventral_progenitors_and_neurons_2|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.

SLC9A4 RNASEH2B

4.34e-0417982d95367d689732ab2653e8d70d8d8e5eb15ae6eef
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC9A4 DOCK10

4.39e-0418082023ec0b080c8a5cd0f36e83c6b17d4be3c01edb5
ToppCellCOVID-19-kidney-NK|COVID-19 / Disease (COVID-19 only), tissue and cell type

DOCK10 SACM1L

4.44e-04181828906ee8a7a1616dfe8c3b5c73988416641213629
ToppCelldroplet-Lung-nan-3m-Myeloid-alveolar_macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC9A4 DOCK10

4.58e-04184823261d767d5e3d9e9fbac22ad73ca14e44beed89c
ToppCelldroplet-Lung-LUNG-1m-Myeloid|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC9A4 DOCK10

4.63e-041858253a5218c1e6eb12daccde3d6e02f337e2586d74c
ToppCell343B-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0.5|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

RNASEH2B SACM1L

4.68e-0418682bbb8edea8d8bdc1a469faec1563e40b1f62d7f3d
ToppCelldroplet-Lung-nan-18m-Myeloid-Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC9A4 DOCK10

4.73e-0418782f20e7a1751694390f535ffb27b97e887220f8695
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_GGH|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DOCK10 CCDC180

4.73e-0418782eb011a3d8a3025cebb0fba36d403be906305372c
ToppCelldroplet-Lung-nan-18m-Myeloid-alveolar_macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC9A4 DOCK10

4.73e-0418782f0c6e53035b00772377c4d5f761b4d11026b911a
ToppCelldroplet-Lung-LUNG-1m-Myeloid-alveolar_macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC9A4 DOCK10

4.83e-04189826d24414ac6bd4f03f7a5ad3a6eba51d549a7b112
ToppCelldroplet-Lung-1m-Hematologic-myeloid-alveolar_macrophage-alveolar_macrophage|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SLC9A4 DOCK10

4.83e-0418982b2542b6fcf7bc10d29158d42b03182a939ff135a
ToppCelldroplet-Lung-LUNG-1m-Myeloid-Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC9A4 DOCK10

4.83e-0418982287e59104687fe1665232c52993889f0f2c97f17
ToppCelldroplet-Lung-1m-Hematologic-myeloid-alveolar_macrophage|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SLC9A4 DOCK10

4.89e-0419082da58227565ad6a690828dd8554dd3670222f8582
ToppCelldroplet-Marrow-BM-1m-Hematologic-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RNASEH2B DESI1

4.99e-041928219b8675ed8a99bd3d08ad043e4ec9f006426c22f
ToppCelldroplet-Thymus-nan-3m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RNASEH2B DESI1

4.99e-0419282041124dd5c24c1eb188d2560ba606422c0b215c5
ToppCelldroplet-Marrow-BM-1m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RNASEH2B DESI1

4.99e-0419282ced2fdbcb181ac250ff50cd4d5d886e568924203
ToppCelldroplet-Thymus-nan-3m|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RNASEH2B DESI1

4.99e-0419282d9e61b2722aa81e4f6e11865a04f2f1e75b794ab
ToppCelldroplet-Lung-1m|Lung / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SLC9A4 DOCK10

5.09e-0419482d16ab5f0cfe73afe6c551fd3123d14784a082f56
ToppCelldroplet-Lung-LUNG-1m|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC9A4 DOCK10

5.09e-0419482621e0e8fe77ff0be83ea9287ce46e97c47e2b3b9
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Macroglial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK10 DESI1

5.20e-0419682f068ce40bf35021baf1468ae9ce30a92162eb14d
ToppCellLPS_IL1RA_TNF-Hematopoietic_Myeloid-Dendritic_cells-pDC|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

DOCK10 RNASEH2B

5.25e-04197828fa38fb95e285f9cc756ec4f32009be4ede09d3c
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Macroglial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK10 DESI1

5.25e-04197827b12f9d4ad1e84df58e86591a491c84d4f36eac5
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Macroglial-oligodendrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK10 DESI1

5.30e-041988297ae237f955fd5fbd01d06aafe89ef9e6f777a9a
ToppCellLPS_only-Epithelial_airway-airway_epithelial-Ciliated|LPS_only / Treatment groups by lineage, cell group, cell type

SLC9A4 CCDC180

5.30e-04198826d90b541fde357fbb40f8f7d4e8628a48b679718
ToppCellParenchymal-NucSeq-Epithelial-Epi_submucosal-gland|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SLC9A4 MMP13

5.30e-0419882fab3135f03cf23a9f04f0eed543a9dc181f39f5f
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Macroglial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK10 DESI1

5.30e-0419882fef9a4c96450078527b94d25e681410e4ea01b13
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Macroglial-oligodendrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK10 DESI1

5.30e-0419882a183afe4c2034323f77abfa080f359d67da35e8f
ToppCellLPS_only-Epithelial_airway-airway_epithelial|LPS_only / Treatment groups by lineage, cell group, cell type

SLC9A4 CCDC180

5.30e-0419882e035380578c01b0243bfef29ca9b50cc17cce771
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Macroglial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK10 DESI1

5.30e-041988227f0654fb0857e93f030e1a4b1c307b31576bbcd
ToppCellLPS_only-Epithelial_airway|LPS_only / Treatment groups by lineage, cell group, cell type

SLC9A4 CCDC180

5.30e-0419882ba090210392e001a3f7bdf09371b3f0e0c8c7ef3
ToppCellLPS_IL1RA-Hematopoietic_Myeloid-Dendritic_cells-mDC|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

DOCK10 RNASEH2B

5.30e-0419882e8002972410e4803d85263ba2642e6855cef83e9
ToppCellLPS_IL1RA-Hematopoietic_Myeloid-Dendritic_cells|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

DOCK10 RNASEH2B

5.30e-0419882ba3b97bb3e1533df758e845bde7d82eb1525b057
ToppCellLPS_anti-TNF-Epithelial_airway-airway_epithelial-Ciliated|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

SLC9A4 CCDC180

5.36e-041998215f7814b7074170eee7ccacaa670b1d128fc68bb
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Macroglial-oligodendrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK10 DESI1

5.36e-041998267d8c7e5356f5d409d4f98e8338cf6c499fd7aee
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Macroglial-oligodendrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK10 DESI1

5.41e-0420082e5b4821fff40566c4a7dc3f74a14e27eb06b165d
ToppCellLPS_IL1RA-Epithelial_airway-airway_epithelial-Ciliated|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

SLC9A4 CCDC180

5.41e-04200824992dbf0514d674017315dbd20d91dfec0c608e9
ToppCellLPS_IL1RA_TNF-Epithelial_airway-airway_epithelial-Ciliated|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

SLC9A4 CCDC180

5.41e-042008296701a4d57753f5ec0dd5c7550054bbcc946bc5f
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Macroglial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK10 DESI1

5.41e-042008256f1f007ba8c9188a4b10e52744f1e50dc0f155a
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Macroglial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK10 DESI1

5.41e-04200820e85c90719d9ec51a566e230c9dd2909d8df1f52
Drugalendronate

MMP13 MAN2C1

4.26e-049082CID000002088
Drugtroglitazone; Down 200; 10uM; PC3; HT_HG-U133A

MMP13 DOCK10

1.86e-03189821232_DN
DrugLY 294002; Down 200; 10uM; PC3; HT_HG-U133A

DOCK10 DESI1

1.90e-03191824451_DN
Drugpioglitazone HCl; Down 200; 10uM; PC3; HT_HG-U133A

MMP13 DOCK10

1.92e-03192825930_DN
DrugLY 294002; Down 200; 10uM; PC3; HT_HG-U133A

DOCK10 DESI1

1.94e-03193824460_DN
DrugL(-)-vesamicol hydrochloride [112709-59-8]; Up 200; 13.6uM; PC3; HT_HG-U133A

MMP13 DOCK10

1.96e-03194825056_UP
DrugCP-690334-01 [459212-38-5]; Down 200; 1uM; PC3; HT_HG-U133A

MMP13 DOCK10

1.96e-03194823826_DN
DrugDiprophylline [479-18-5]; Up 200; 15.8uM; PC3; HT_HG-U133A

MMP13 DOCK10

2.00e-03196825063_UP
DrugThiamphenicol [15318-45-3]; Up 200; 11.2uM; HL60; HT_HG-U133A

DOCK10 MAN2C1

2.00e-03196821867_UP
DrugEtilefrine hydrochloride [534-87-2]; Up 200; 18.4uM; MCF7; HT_HG-U133A

MMP13 DOCK10

2.00e-03196824415_UP
Drug0173570-0000 [211245-44-2]; Down 200; 1uM; PC3; HT_HG-U133A

RNASEH2B MAN2C1

2.00e-03196827391_DN
DrugChloroquine diphosphate [50-63-5]; Up 200; 7.8uM; PC3; HT_HG-U133A

DOCK10 RNASEH2B

2.00e-03196827251_UP
DrugN6,2-O-dibutyryladenosine 3,5-cyclic monophosphate sodium salt; Up 200; 2uM; MCF7; HT_HG-U133A_EA

RNASEH2B MAN2C1

2.02e-0319782959_UP
DrugICI182,780; Up 200; 1uM; PC3; HT_HG-U133A

MMP13 RNASEH2B

2.02e-03197827495_UP
DrugMethylatropine nitrate [52-88-0]; Up 200; 11uM; PC3; HT_HG-U133A

MMP13 RNASEH2B

2.02e-03197827253_UP
DrugKetorolac tromethamine [74103-07-4]; Down 200; 10.6uM; PC3; HT_HG-U133A

RNASEH2B DESI1

2.02e-03197827286_DN
DrugMethylhydantoin-5-(D) [55147-68-7]; Up 200; 35uM; MCF7; HT_HG-U133A

MMP13 DOCK10

2.02e-03197824113_UP
DrugAmiloride hydrochloride dihydrate [17440-83-4]; Up 200; 13.2uM; PC3; HT_HG-U133A

MMP13 DOCK10

2.02e-03197823990_UP
DrugDyclonine hydrochloride [536-43-6]; Up 200; 12.2uM; PC3; HT_HG-U133A

MMP13 DOCK10

2.04e-03198827261_UP
DrugMianserine hydrochloride [21535-47-7]; Down 200; 13.2uM; PC3; HT_HG-U133A

MMP13 DESI1

2.04e-03198822068_DN
DrugMeclofenamic acid sodium salt monohydrate [6385-02-0]; Up 200; 11.8uM; PC3; HT_HG-U133A

MMP13 DOCK10

2.04e-03198827280_UP
Drug0225151-0000 [351320-15-5]; Down 200; 10uM; PC3; HT_HG-U133A

MMP13 DESI1

2.04e-03198826426_DN
DrugLevonordefrin [829-74-3]; Up 200; 21.8uM; MCF7; HT_HG-U133A

MMP13 RNASEH2B

2.04e-03198823450_UP
DiseaseLiver Cirrhosis, Experimental

MMP13 DOCK10

1.73e-0277482C0023893
Diseasesystemic lupus erythematosus

SLC9A4 DOCK10

1.84e-0279982MONDO_0007915
Diseaseserum metabolite measurement

CCDC180 SACM1L

2.52e-0294582EFO_0005653

Protein segments in the cluster

PeptideGeneStartEntry
MENFKEHHWKKFFTS

CCDC180

1461

Q9P1Z9
EHHWKKFFTSVKEIR

CCDC180

1466

Q9P1Z9
HSEVEKAFKKAFKVW

MMP13

131

P45452
TTVKHVLKHSWFFFA

DOCK10

981

Q96BY6
IWHTSIVVHKDEFFF

DESI1

36

Q6ICB0
EVHWHEAHKFLKVEF

MAN2C1

801

Q9NTJ4
TKKIKVGEFFSHVVW

SACM1L

76

Q9NTJ5
HWSHYQVRDKFKKFD

SLC9A4

511

Q6AI14
FEVKVFKEKHHSWFI

RNASEH2B

61

Q5TBB1